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These are the user uploaded subtitles that are being translated: 1 00:00:00,600 --> 00:00:07,680 [Music] 2 00:00:07,680 --> 00:00:09,519 the early childhood brain development 3 00:00:09,519 --> 00:00:10,240 story 4 00:00:10,240 --> 00:00:12,799 has been a powerful influence on the 5 00:00:12,799 --> 00:00:14,160 growth of investments 6 00:00:14,160 --> 00:00:16,320 in programs to promote early learning 7 00:00:16,320 --> 00:00:18,480 and enhance school readiness 8 00:00:18,480 --> 00:00:22,720 but the brain does not exist by itself 9 00:00:22,720 --> 00:00:24,640 connecting the brain to the rest of the 10 00:00:24,640 --> 00:00:27,199 body is critically important 11 00:00:27,199 --> 00:00:30,400 early childhood experiences are as much 12 00:00:30,400 --> 00:00:32,719 about lifelong physical and mental 13 00:00:32,719 --> 00:00:34,239 health as they are 14 00:00:34,239 --> 00:00:36,719 about early learning and readiness to 15 00:00:36,719 --> 00:00:38,399 succeed in school 16 00:00:38,399 --> 00:00:40,559 all biological systems all of them are 17 00:00:40,559 --> 00:00:42,160 highly interconnected and 18 00:00:42,160 --> 00:00:45,840 all of these systems are primed to adapt 19 00:00:45,840 --> 00:00:47,440 to whatever the environment they throw 20 00:00:47,440 --> 00:00:49,520 at us think about this 21 00:00:49,520 --> 00:00:52,399 as a team of highly skilled athletes 22 00:00:52,399 --> 00:00:54,879 each has a role to play but they depend 23 00:00:54,879 --> 00:00:56,960 upon each other they influence each 24 00:00:56,960 --> 00:00:58,640 other's responses 25 00:00:58,640 --> 00:01:01,120 like any good team it's how they operate 26 00:01:01,120 --> 00:01:01,920 together that 27 00:01:01,920 --> 00:01:04,879 is the key to their success when we are 28 00:01:04,879 --> 00:01:05,920 stressed 29 00:01:05,920 --> 00:01:08,560 every cell in the body is working 30 00:01:08,560 --> 00:01:09,439 overtime 31 00:01:09,439 --> 00:01:12,000 the brain is the master control system 32 00:01:12,000 --> 00:01:13,119 that detects 33 00:01:13,119 --> 00:01:15,600 threat and then manages the response of 34 00:01:15,600 --> 00:01:16,640 all of the different 35 00:01:16,640 --> 00:01:19,040 systems it sends signals to the 36 00:01:19,040 --> 00:01:21,119 cardiovascular system to increase heart 37 00:01:21,119 --> 00:01:22,720 rate and blood pressure 38 00:01:22,720 --> 00:01:24,880 signals are picked up by metabolic 39 00:01:24,880 --> 00:01:26,000 systems to increase 40 00:01:26,000 --> 00:01:28,320 the availability of blood sugar to 41 00:01:28,320 --> 00:01:30,560 provide more energy stores for the body 42 00:01:30,560 --> 00:01:32,720 the immune system is activated to be on 43 00:01:32,720 --> 00:01:34,960 alert for the possibility of a wound 44 00:01:34,960 --> 00:01:37,280 or the need to protect against infection 45 00:01:37,280 --> 00:01:39,759 the neuroendocrine system is activated 46 00:01:39,759 --> 00:01:40,640 to increase 47 00:01:40,640 --> 00:01:42,240 levels of stress hormones in the 48 00:01:42,240 --> 00:01:43,840 bloodstream all of these 49 00:01:43,840 --> 00:01:46,399 also provide feedback to the brain the 50 00:01:46,399 --> 00:01:47,920 stress response system 51 00:01:47,920 --> 00:01:50,159 was designed to deal with an acute 52 00:01:50,159 --> 00:01:51,600 threat or challenge 53 00:01:51,600 --> 00:01:54,240 but when the stress continues at a very 54 00:01:54,240 --> 00:01:55,280 high level 55 00:01:55,280 --> 00:01:58,640 then these biological responses actually 56 00:01:58,640 --> 00:02:01,280 start to have a wear and tear effect 57 00:02:01,280 --> 00:02:04,399 on the body this is where stress 58 00:02:04,399 --> 00:02:07,360 explains chronic disease the science is 59 00:02:07,360 --> 00:02:08,479 really clear 60 00:02:08,479 --> 00:02:11,360 the most costly chronic diseases in our 61 00:02:11,360 --> 00:02:12,239 society 62 00:02:12,239 --> 00:02:14,080 have their roots in early childhood 63 00:02:14,080 --> 00:02:16,239 cardiovascular disease diabetes 64 00:02:16,239 --> 00:02:19,120 and depression three of many diseases 65 00:02:19,120 --> 00:02:20,400 that are associated with greater 66 00:02:20,400 --> 00:02:22,160 adversity early in life 67 00:02:22,160 --> 00:02:24,400 those three diseases together consume 68 00:02:24,400 --> 00:02:26,720 more than 600 billion dollars 69 00:02:26,720 --> 00:02:29,440 of health care costs a year so if we 70 00:02:29,440 --> 00:02:30,560 want to think about 71 00:02:30,560 --> 00:02:33,840 preventing disease and promoting health 72 00:02:33,840 --> 00:02:36,000 it doesn't begin with exercising more 73 00:02:36,000 --> 00:02:37,760 and eating better when you're 30 or 40 74 00:02:37,760 --> 00:02:38,319 years old 75 00:02:38,319 --> 00:02:40,400 health promotion and preventing disease 76 00:02:40,400 --> 00:02:42,640 begins prenatally and it extends into 77 00:02:42,640 --> 00:02:44,959 the early childhood period 78 00:02:44,959 --> 00:02:46,800 connecting the brain to the rest of the 79 00:02:46,800 --> 00:02:49,280 body has very important implications 80 00:02:49,280 --> 00:02:51,680 for early childhood policy if we look at 81 00:02:51,680 --> 00:02:52,400 the basic 82 00:02:52,400 --> 00:02:54,640 science-based principles focused on 83 00:02:54,640 --> 00:02:55,440 early learning 84 00:02:55,440 --> 00:02:57,519 strengthening relationships building 85 00:02:57,519 --> 00:03:00,239 skills reducing sources of stress 86 00:03:00,239 --> 00:03:02,159 those are the same principles that 87 00:03:02,159 --> 00:03:03,519 increase the likelihood 88 00:03:03,519 --> 00:03:06,319 for lifelong physical and mental health 89 00:03:06,319 --> 00:03:07,680 and when we think about the major 90 00:03:07,680 --> 00:03:09,840 sources of adversity early in life 91 00:03:09,840 --> 00:03:12,239 we talk about poverty discrimination 92 00:03:12,239 --> 00:03:13,599 exposure to violence 93 00:03:13,599 --> 00:03:16,000 maltreatment child abuse and neglect 94 00:03:16,000 --> 00:03:17,440 although each of these 95 00:03:17,440 --> 00:03:19,440 sources of adversity differ from each 96 00:03:19,440 --> 00:03:20,720 other biologically 97 00:03:20,720 --> 00:03:22,879 the effect on the body is the same 98 00:03:22,879 --> 00:03:24,319 systemic racism 99 00:03:24,319 --> 00:03:26,720 the dangers of implicit bias and 100 00:03:26,720 --> 00:03:27,680 everyday 101 00:03:27,680 --> 00:03:30,640 discrimination impose a level of stress 102 00:03:30,640 --> 00:03:32,799 and adversity on families of color 103 00:03:32,799 --> 00:03:33,760 raising children 104 00:03:33,760 --> 00:03:36,560 that is present all the time it's never 105 00:03:36,560 --> 00:03:38,080 too late to make things better 106 00:03:38,080 --> 00:03:41,200 and we are biologically prepared to 107 00:03:41,200 --> 00:03:42,799 adapt to whatever environment 108 00:03:42,799 --> 00:03:46,080 we live in but we need to look upstream 109 00:03:46,080 --> 00:03:48,480 at more systemic issues that are the 110 00:03:48,480 --> 00:03:49,200 sources 111 00:03:49,200 --> 00:03:52,239 of this enormous burden of threat 112 00:03:52,239 --> 00:03:55,920 and hardship we have to connect policies 113 00:03:55,920 --> 00:03:58,319 and resource allocations from the 114 00:03:58,319 --> 00:04:00,480 educational sector and the health sector 115 00:04:00,480 --> 00:04:01,120 and human 116 00:04:01,120 --> 00:04:02,810 services sector 117 00:04:02,810 --> 00:04:04,720 [Music] 118 00:04:04,720 --> 00:04:08,080 pediatric primary care is the one domain 119 00:04:08,080 --> 00:04:10,080 where almost all children are seen from 120 00:04:10,080 --> 00:04:11,200 birth on and 121 00:04:11,200 --> 00:04:14,159 provides a critical opportunity for 122 00:04:14,159 --> 00:04:15,920 engagement with families 123 00:04:15,920 --> 00:04:18,160 and developing relationships promoting 124 00:04:18,160 --> 00:04:19,279 healthy development 125 00:04:19,279 --> 00:04:22,560 and is the ideal frontline opportunity 126 00:04:22,560 --> 00:04:24,960 to connect families to needed services 127 00:04:24,960 --> 00:04:27,040 as early as possible when they can be 128 00:04:27,040 --> 00:04:27,440 most 129 00:04:27,440 --> 00:04:30,720 effective pediatrics alone 130 00:04:30,720 --> 00:04:32,479 is not going to provide all of the 131 00:04:32,479 --> 00:04:34,400 supports that many families need 132 00:04:34,400 --> 00:04:36,800 the opportunity is to move away from 133 00:04:36,800 --> 00:04:38,800 asking how do we connect 134 00:04:38,800 --> 00:04:40,639 pediatric primary care to early 135 00:04:40,639 --> 00:04:42,479 childhood programs and 136 00:04:42,479 --> 00:04:44,560 in a different way change our mindset to 137 00:04:44,560 --> 00:04:46,080 say how do we build 138 00:04:46,080 --> 00:04:48,560 a new early childhood ecosystem in which 139 00:04:48,560 --> 00:04:51,150 pediatrics is an integrated part 140 00:04:51,150 --> 00:04:52,240 [Music] 141 00:04:52,240 --> 00:04:55,040 the brain development story has been a 142 00:04:55,040 --> 00:04:55,680 powerful 143 00:04:55,680 --> 00:04:58,880 influence the same principles the same 144 00:04:58,880 --> 00:04:59,919 concepts 145 00:04:59,919 --> 00:05:02,479 are also affecting the early foundations 146 00:05:02,479 --> 00:05:04,160 of physical and mental health that will 147 00:05:04,160 --> 00:05:10,080 last for a lifetime 148 00:05:10,080 --> 00:05:12,160 you 9495

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