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1964 - The bread and wine of the year 2000
Nicols Well, you have no appetite?
No, no, as you want one has appetite
I just read that just introduce another product chemist
You can be the bread monoastearato
and for what?
to prevent it from hardening
as if that was not enough wine dye
insecticide cover apple
meat that comes from animals
fattened with antibiotics
salad ingredients with chemicals
but this is too much!
The list of chemicals that is added
in the power supply increases every day
but is it really we believe about
You know the issue is quite serious because all our future
the power supply of the year 2000
is sufficiently important to the future of the species
for us to do an investigation is necessary
to all those concerned Number of toxicologist of power supply
to clarify on this issue
I tena four years when these were passed imagnes
and pruning have been one of those children sitting at table
Half a century after the research have resumed stopped
and rightly so because at that time
was too early to measure the long-term effects of chemicals
used in the food chain
from the fields to the producer Consumer plate
However, these ESTN everywhere
However these everywhere ESTN
about fruits and vegetables under the form of pesticide residues
in epicera and ready meals
in the form of food additives
or an on packaging and plastic containers
As they have regulated them?
have been testing them seriously?
There is a relationship between these chemicals
To answer these questions I've been around the world
patiently Uniting puzzle pieces
because knowledge is power
The National Audiovisual y Arte France Present
OUR DAILY POISON
A film by Marie-Monique Robin
I am very happy to receive this exploitation
as you see it is a cereal exploitation
no live tock,
here by the early 90 bean intensive agriculture
I make enough in chemistry
and it is also here that had an accident in April 2004
just checking cleaning bucket
on a sprayer with it had just weeding maz
inhaled vapor adjuvant
in a solvent is called
monochlorobenzene was in this code
"On the mazy soybeans
Lasso or any derivative
You can control weeds
Monsanto's herbicide Lasso "
After the ccident
was taken to the emergency room
couple some weeks, but above
pair a few weeks, but above
health problems are
whose few months after which led me
hospitalizacin 5 months and 9 month work stoppage, as is
give me da story today, if you they are here
is because there are several people victims of this product
is that it is a topic that is tab very difficult to talk about it
"My solution: well used herbicides
except weeds "
This fu a first world in January 2010
thirty sick
invited farmers met by the Movement for Respect Law and Future Generations
one environmental organization leading a campaign
about the dangers of pesticides
At the beginning of my career here is symbolic
because the beginning of my career
one tore and now the da
replant hedgerows have here we have a little advance
this side I was ah double title, first as a journalist
because the food chain starts in the fields of farmers but also because
crec on a farm located a hundred kilometers
as all these men and women
my parents were actors of the Green Revolution
that deeply transform the agrcolas activities
the years following the Second World War
The vein pattern of the United States who thanks to
Marshall Plan that it was supposed to help aa rebuild a Europe ruined
massively exported machines and pesticides agrcolas
and all believed in them, they finished scarcity and hunger
and industrial agriculture may feed the world
"These last few years the man managed to
this wealth has given us
the best conditions of life that the world has known jams"
In this model agrcola chemistry has the answer for everything
it provides insecticides to kill insects
herbicides to destroy weeds
Because we gather today we give?
Because we gather today gives?
15 years ago we work in the chemical contamination
especially in the pollution pesticides linked
Franois Veillerette Respect Movement and the Right to Future Generations
and 15 years ago is seen by all sides in the fields of France
Farmers tell us that sick ESTN
sick or having companions
and give answers to the questions that make us
either terms of doctors or legal TOXICOLOGI CAL
because we have talented experts that podrn
give them answers my story, my case
fu might not be more tenacious
but I was lucky to survive that da
can be a bad day for signature that sold me the product
neurolgico had a problem, ie
headache, I know very perda the
here have brutally coma that lasted not much but it was deeper
and sudden today I daa neurolgico treatment level
I'm going to Rennes every six months because lesions appeared
in the brain and there is a very close monitoring of evolution
"Do not Forget jams PESTICIDES ARE POISONS
it is you who should be careful
use pesticides with precaution "
1960 - "Pesticide risks to health" U.S. Department of Health
Pesticides are poison, I have here there the merit of clarity
and high doses can cause what they call
acute poisoning in english "poisoning" a poisoning hazard
these jams have been denied
by the promoters of agriculture
chemistry that makes 50 years ago
did not hesitate to shoot avctimas
acute intoxication with the goal
of therapeutics research and prevention
1970 - Advertising Dupont
According to the World Health Organization
each year from 1 to 3 million people
are victims of acute poisoning by pesticides
and more than 200,000 die from this
with an annual consumption of 80,000 tons
with an annual consumption 80,000 tons
since 1997 the Mutual Social Agrcola MSA
wearing a monitoring program
of acute poisoning
dubbed "phyto attitude"
Fito and Phytosanitary product the term used
Power by the public and industry to designate pesticides
in the year 2009 received the mutual 271 cases of acute poisoning
Dr. Jean Luc Dupupet - by doctor Risk chemist, Social Mutual Agrcola
Know what kind of products are incriminated?
are rather herbicides, fungicides?
Well we have an idea, we
when people have a headache
insecticides are usually
is declining because it is a category
a family of insecticides
tend to disappear
but with insecticides one has
the tendency to emphasize
you say h adache
with fungicides more one observes the cutneas manifestations
with herbicides is digestive or cutneo
d to as diseases professionals agrcola middle?
It is necessary, at the beginning of the years 90, 95 had American Studies
Italians and Scandinavians who have highlighted that
Frequently habacnceres in
agrcola population than in the general population
agrcola Note that there are fewer cases of cancer
in the middle that the population in general
but that certain types of cancer are more represented
and all diseases have also been, I mean cancer
but also talk about
especially diseases neurolgicas PD
and that disease seen in
certain people in certain farmers recognized
as an occupational disease since
an increased risk of this disease linked to the utilization of the
"phy o"
Products If the doctor Dupupet response has been so laborious is because
to a recent date the impact long term
pesti ide
Long term pesticide
on the users was a subject tab
prevention messages pointed ONLY
cases of acute poisoning but jams
the chronicle dbiles dose exposure to and repeated in time
multiplication of epidemiolgicos studies
has forced the mutual break progressively silence
An example, Parkinson's disease
have established a relationship between the chronicle exhibition
to pesticides and neurodegenerative pathologies such
I escog two, one fu
done by the National Institute of Health and of Medical Research
in collaboration with the physicians work
the MSA and the other by the Parkinson Institute in California
Each study was performed on a group of
at least 150 sick
compared to an equivalent group
baptized not sick as a "control group"
Caroline Tanner, Parkinson's Institute Neuro epidemiologist
Our main result is you three chemical substances
ESTN strongly associated with the risk of disease
Parkinson's first is the 2,4-D is a herbicide that
the second the other herbicide Paraquat
and the third Permethrin is an insecticide that
Alexis Elbaz, Neuroep demiologista-INSERM
The insecticides had watched that
a very particular relationship between organochlorine insecticides
for which the risk was a little ms
that high assembly with increased risk by 2.5
The risk may be greater than 2.5 to 3
There are times like DDT has been banned long
or Lindane has been used to the end of a 90s os
which has banned more recently is Endosulfn
in most countries in any case Western
for agricultural utilization queue as the character
very persistent in the environment
To this da farmers thirty patients have been recognized as
professional disease, of which
10 for disease Parkinson
10 for Parkinson's disease
To the sick gathered Ruffec this is not enough
that the MSA gives them the status of "dropper"
but the change in attitude of mutual is a first in the world
Okay, now is the time to give the word
people who have already been recognized
as occupational diseases
to show case already took place, is your case?
I here what happened to me, in the year 98
inhale the Gaucho ( Monsanto pesticide) gives a whole night
I was sick, the doctor came
I vomited, he made me a part
in which deca I had inhaled the Gaucho
in the year 2002 I went to see a neurologist in nuclear medicine
who I Tours said you have the PD
and she told me frankly, that can come
the pesticide you inhal
I'm unemployed for the last 7 years
I'm in Paris now gives the past 18 months
Why? simply because in Paris
Live incgnito, frankly I'm free free
I will be in the field and will make me as
I will point the finger
I will not be able to live in the countryside
Often the victim where
is pointed the finger for their own means?
Paul Franois, Farmer
To my colleagues at the beginning farmers decan
excuse me but you shut your mouth because annoying
if you are more sensitive than others
is your fault because we have always used
we are not sick
and now yields 6 years after not passing I tell ten das
without me receiving a phone call
people w ether
ESTN sick or begin to reason
otherwise have reason for saying
we have a part of responsibility
this pollution of the environment and the first victims will be us
Forward, orward
Yannick Chenet, Farmer
I am Yanick they'm farmer Saujon
,
Charente Maritime ca ill in October 2002
I acquired acute leukemia, Eloic type 4
then in 2003 made me one graft surgery
medulla function of whether either CHU Poitiers
of the surgery against me that is to say the surgery
the person who gave me the medulla is
and reacting against my heart surgery
day gives the skin problems have
and refraction of tendons and skin escloredermine
dry eyes and many other problems
dry eyes and many other problems
Dr. Jean Luc Dudupet, Physicians chemist in charge of Risk - MSA
They are only cnceres that are recognized
diseases such as professional?
ESTN the blood cnceres
indeed those that were found
found more frequently
in studies epidemiolgicos
what is leukemia, non-Hodgkin lymphoma
also is the cancer of the
tambincncer prstata skin
I think about the pesticide manufacturers?
In France they are represented by the Union of Industries
Protection of Plant (UIPP)
which brings together 19 members, among which
6 ESTN industry giant BASF Agro, Bayer, Down
Dupont, Monsanto and Syngenta
Jean-Charles Bocquet; Director UIPP
Jean-Charles Bocquet; Director UIPP
Today gives no evidence
that allows some correlation
accurate between the appearance certain diseases
and exposure to product fitofarmacutico
A fifth believe?
MSA of a hand, giving the state
occupational disease
farmers with cancer
the other a representative of industry
which states that the relationship between pesticide
To see more clear I have contacted the International Centre
for Research on Cancer (IARC) that depends
WHO in 2007 entered the CIRC to a report
which was published by the Academy French
of Medicine and Science
entitled The Causes of Cncer in France
the snuff designated the
as the leading cause of disease
and stated that only 0.5% of
cancer are due to the chemical contamination
are due to the chemical contamination
At its board cnceres attributable to exhibitions
the ignorant professional pesticide
and conclua: putative relationship
between pesticides and cancer
not based on data ningn slido
In the field of cancer
the CIRC is an international reference
is the fifth monograph sets
ie the classification of the chemicals
in function of its potential cancergeno
paramount tool
the ruling of substances
their experts to examine this the scientific literature
concerning the product to know all published studies
that is what they call
the revision of the Reading Committee
Substances are classified 4-categories
Group 1: Cancergenos for Men
exceptional category because
there needs to be epidemiolgicos data
so it is very difficult to get
is the case of asbestos or benzene
then comes the Group 2A: Probable Cancergenos
for Men Group 2B: Possible Cancergenos ,
which characterize the substances of which there are experimental data
in the more or less important Animal
about 100,000 chemicals marketed products
after the end of the World War II
only 900 have been evaluated by the CIRC
of which more than half
is part of Group 3: Unclassifiable
Vincent Cogliano, head of Program IARC monographs
The fact that a product
no chemist has been classified by the CIRC
means that it is not dangerous?
Not completely, just means that
most cases have not been tested
that means that anyone considered
this data for cancer or anyone
a studied cancergenos potential effects
Really I have not counted but I think we have
evaluated twenty or thirty pesticides
in the history of our program
But that's nothing
It is true that it does not look like much if you compare
In fact it is very difficult for us
to make an evaluation pesticide serious n
because most experimental studies
concerning them are not pblicas
certainly assume that the signatures
which produce pesticides must provide
their studies to the National Health Agencies
because they do tests and studies
are forwarded to the Government Agencies
but are not published
is very difficult for us to access
As you explain the fact that studies conducted by
of the Committee Cientfica Reading?
Suddenly is not the interest of firms
Maybe it is not the interest of firms
publish results that suggest
that their products can be harmful
anyway they are obligated not
make public their studies
Saba you that in 2007 the
French Academies of Medicine and Science
have published a report with the CIRC
with the title "The Causes the Cncer in France "?
Thanks
We currently are not cancergenos in the animal or in man
I have consulted their monographs
and I've found at least
dichlorvos and lorotalonile
if they have been ranked
2B means that studies have shown are cancergenos
at least in animals
If you still are used and I'm pretty sure
they are in animals cancergenos
That means the affirmation
in this report is incorrect
Yes, I think it is
1964 "The bread and wine to or 2000 "
In theory should not be insecticides jams
in the food we eat
but it is not the case today unfortunately da
quickly but
How to know if during these traces not favorecern
All good questions and
have been made 50 years ago, if pesticides are toxic
to the point of illness to users
what about waste one finds
in fruits and vegetables treated?
Geneva, Sw tzerland
To answer these questions it is necessary
understand how it works the ruling of the
chemicals the current system has been developed
at the end of the years 1950 low conducted by WHO
FAO in collaboration with the Organization of the
Looking in the archives, I discovered a
toxic ogo
Looking in the archives, I have found that a toxiclogo
Capital francs a role pl on site
tools designed to regulate substances
entering qumicas food contact
The name was Ren Truhaut, the respondent had been
by my colleagues 50 years ago
1964 "The bread and wine of the year 2000"
Ren Truhaut
I can understand so that front
the pressure of the chemical Aument of sb
in the last century when our citizen of the world
and well in the food domain specifically
has been given a great importance
to microbiolgico food control
and has founded a number of all laboratories
to exercise supervision and well be necessary
it is in the morning
If control of agents chemicals added to foods
because their effects may be more insidious
less spectacular if you want
but as I see serious opinin
Ren Truhaut is considered the father
of what we call
Permissible Dose laborer or acceptable with jargon DJA
first conceived for Ruling food additives
this principal toxicologist
then Extendi tool for pesticide residues
here the definition that gives Ren Truhaut:
" Allowable Dose laborer is the number
food additive that can be ingested daily throughout
a life without no risk "
Interestingly no one knows
really like the DJA was invented
while she is supposedly
to protect our health of chemicals risk
The only person that He found
is called Diane Benford, toxicloga
of Britnica Food Standards Agency
She is the author a document entitled "Permissible Dose
one laborer tool for ensuring food security
", where fu
published by ILSI a body which is funded by multinational
of the chemical and the agroalimentacin
In his part histrica Diane Benford
is content with naming and Ren Truhaut
quote Paracelsus a Swiss physician of the sixteenth century
regarded as the founder of toxicologist
"Anything can be a poison is the dose
makes the difference between a poison and a remedy"
Diane Benford, Head of Risk Appraisal of chemist, Food Standards Agency
The concept forms the basis of the DJA
The concept which forms the basis of the DJA
is the principle of Paracelsus "The dose makes the poison"
Is this true?
It is true
What does this mean exactly?
That means that the probability have toxic effects
increases with dose but fundamentally
is true for all This includes water or oxygen
without which We could not live
if large absorvemos
quantities that can also be harmful
with the greatest amount of As more elements
reduced the dose, decreases the probability
have negative effects
It is what toxicologists call the dose-effect relationship?
Correct
Not only the severity of effect increases with dose
but also the number of individuals
having a negative REACTION
If I understand well, the whole part evaluation process
the principle that all substances
qumicas are txicas
one tries to find a dose
involving not have any effect
It is correct
1958 - "Pesticide risks to health"
As seen here
a drop of insecticide can be fatal
Specifically laborer Allowable Dose
is computed from from studies
Laboratory Animals
First Step: You are given a group of guinea pigs
high doses of chemicals
will generally oral
the goal is to determine why one called
Lethal Dose or jargon LD50
ie the dose that kills half of the animals
Second stage: the dose is decreased
to observe the effects on guinea pigs
for example is whether products
daan tissues or organs
if the cause effects on the nervous system
or immune and Wanted particularly interested us
at potential cancergeno
because of course it is something that concerns people
a dose that apparently brings
any effect on animals
is what we call the NOAEL ie
Dose No Observed Effect TOXIC
then to calculate the DJA to serve
apply a safety factor by dividing the NOAEL 100
finally DJA is a value expressed in
milligrams of product per kilo of body weight
one DJA 0.2 mg / Kg
if the consumer weighing 60 kg is assumed that
can consume 60 times 0.2 mg / Kg ie 12mg daily for da
lifet me
without their health being affected
You can say that No-toxic dose
Observed Effect is a safety threshold?
In life there is no domain
wherein one can guarantee absolute security
one runs the risk of going off
the facts you may have noticed
if the study was of good quality
Ned Groth Expertise in environment
is a confusing as it is not extremely accurate
is why the
persons managing used an uncertainty factor, the standard form
applying a factor of hundred
is what is considered a factor 10
to consider the difference it can
exist between animals and humans
then a new factor of 10
by the difference in sensitivity
between humans themselves
The question is whether it is sufficient to know ?
Numerous those who argue that
this factor of 10 to account
This factor of 10 to account
of human variability is too weak
by the same dose can have an effect
zero for certain people
but others may be huge
Pr Erik Millistone, Professor of Policy How Cientfica, University of Switzerland
The safety factor is supposed to be one hundred
each is a figure of heaven and scribbled
on a corner of the tablecloth
That was decided four around a table
That's what Bob Shipman had
one of the oldest in the Food and Drug Administration
in a conference that asist said:
"Fu in the years 1960, was
encontrramos need a way to determine which level of output
pruned to allow food
we met and ah is, what Did "
While we wait, the DJA is
While we wait, the DJA is
absolute reference value
for experts to regulate
the chemicals that pollute
our food chain
As here in the European Authority EFSA
for Food Safety
Fontier Herman, Head of EFSA Pesticide
Takes you to be a DJA scientist the concept?
clear cientficas research
there is a consensus in the scientific world that was to fix the DJA
Pr Erik Millistone, Professor of Scientific University deSuiza Policy How
There is a concept cient fico
ris
but its acceptability acceptability however the notion is a
essentially social, regulatory, and commercial policy
essentially social, regulatory, policy or commercial
acceptable, but acceptable to whom?
and behind the notion of acceptability
is always the question
Risk is acceptable pro of course benefit?
but those who take benefits of utilization of chemicals
companies are always and not consumers
therefore consumers are running the risk
1960 "Pesticide risks to health"
The research allowed to use these poisons
These men drink large doses of pesticides
fruits, vegetables and other foods
search for traces of pesticide
Our foods are tested for
average amount of pesticides we ingest daily
For serving the DJA if you do not
you consider the level pesticide residues found
about fruits and vegetables treated?
To do the experts have invented a second
Limit Mximo of Waste with jargon LMR
Fontier Herman, Head of the EFSA Pesticide
What is the MRL?
Well, that is the number
can be found in a food product
amount expressed in milligrams of pesticides, pesticide residue
per kilogram of foodstuff as well
FIXING LMR n
is the result of a fairly complex process
Pretty complex? certainly
Consider a i secticide
Take for example an insecticide
having a laborer Allowable Dose
0.01 milligrams per kilo of body weight
the insecticide may be used on
twenty fruits and vegetables
As we know if we consumers
not reach sb gives the dose
considered insecticide acceptable?
To do our persons managing should evaluate
our potential exposure by measuring
the amount of residue left
on each product agrcola after harvest
thanks to field testing and then studies are needed
determining consumption that fruits and vegetables
and how much we eat daily
given our food consumption habits
Beaching of a country or from one continent to another
The result, allowing thousands of figures set the maximum limit
Quin sets this figure?
A United Nations agency that responds to the barbarian name
Elaboration of the international Food
Rules the is advised by two committees dependent WHO and FAO
the Joint Expert Committee on Food Additives
called JECFA and the Joint Committee on the
Gene a
I have obtained the exceptional authorization to attend the annual meeting of JMPR
comprised of international experts whose mission is to analyze the
data toxicolgicos pesticide
to set the DJA but also to fix
the MRL for each product agrcola
During the session in September 2009
twenty pesticides have been evaluated among which
chlorpyrifos-methyl an insecticide manufactured
by the American firm Daw Agro Sciences
Bernadette Ossendorp, Chairman of the FAO JMPR
Take for example the chlorpyrifos-methyl
which is used as an insecticide worldwide
How can we tell if a consumer
has not reached a DJA
chlorpyrifos-methyl simply eating
3 blocks and two grapefruits for example?
If I understand your question
you should know that the MRL level value
we evaluated is much more elevated
that your actual exposure
according to our monitoring program
we know that all apples you eat
can not be treated with chlorpyrifos-methyl
must understand that Our evaluation of consumption
case corresponds to a theoretical "worst"
this has nothing to do with the real world
in the real world you will have on your plate
a mixture of potatoes that habrn been treated
carrots or lettuce also
that have not been treated
therefore the probability you receive
a given high doses of residues of this pesticide
is extremely low
Honestly, it is not really that insurer
specifically this evaluation categorical in the "worst"
is calculated based on data sent by the industry
this occupies kilometers of shelves in the subterranean WHO
for each pesticide manufacturer's packaging
thousands of pages concerciente
TOXICOLOGI CAL studying and medicin of waste
during the field tests
Evil tongues say is an industry strategy
to flood the experts verify data difciles
It is impossible to know how the experts work
because we have not been authorized
to record the sound of the debate
in effect on JMPR everything is secret
the identity of the experts ,
content of sessions that have a door closed
and the data submitted by industry
which are covered by the "trade secret"
Pr Angelo Moretto, President of JMPR 2009
Pr Angelo Moretto, President of JMPR 2009
I have reviewed the list of studies has sent
Dow Agro Sciences
the manufacturer of chlorpyrifos-methyl
is interesting because all are "unpublished"
and covered by the "Data protection"
you can check for yourself
Yes, it is quite possible, studies
providing industry JMPR
or national authorities data are protected
a confidentiality clusula
but if you consult the document occurred
by the JMPR and national authorities
Guests may find a summary largest of these data
The summary data but not in "raw"
No, not the raw data for that
belongs to the manufacturers
you have to rely in them by the analysis
and the interpretation Correct Data
The practice of keeping data secret
only serves the commercial interests of the qumicas companies
it is not at all in favor of
consumer interests and health p Republic
WHO and Agencies Ruling
not at all deserve the confidence of the public
, WHO Secretary for JMPR and JECFA
Because the data is protected?
It is because of the right of "intellectual property" are legal problems
,
data are private and belong to the company that transmits
ustede must therefore ask
to the industry because as
Pr Erick Millestone, Professor of Policy How Scientific University of Switzerland da
Only the data comprising the manufacturing process
Product may justify clusula
confidentiality, because it represents information
but otherwise all data TOXICOLOGI CAL
concerning security or
Product toxicity duty to be public domain
Angelika Trischer, WHO Secretariat JMPR and JECFA
If one takes as an example the snuff
with the studies provided by the manufacturers, these were defective
provided by the manufacturer, these were defective
and an engineered, forged
and WHO has been deceived by them during many years by industry
I have a comment about this
But it is true than I comment
In addition this happened before my arrival
the organization, not have all the details
It is a painful story here
If it's clearly a painful history
but the fact that the "data protection"
has a huge discussion here and see either
where we take in the future
While waiting one thing is sure
for industry what is at stake is enormous
annual pesticide market
represents 25 billion EUR
and 140 are sprayed tons each to or
each pesticide has its DJA and LMR
For each category of product agrcola
when you see all these numbers, one that says
regulations all these beautiful buildings
will be able to be reassuring if the DJA and MRL
Scientists values ??were quite safe to be definitive
but it is not the case, so we the example of procymidone
a fungicide that has been re examined
by JMPR Authority to Order
Foundation for the
Pr Angel Morello, President of the JMPR 2009
The European Union has expressed its concern
with respect to the limits that habamos set
You Tenan Food Safety reason finally EFSA has lowered the DJA of procymidone
here I document the EFSA I quote "with the purpose to change
the MRL in order to reduce exposure
consumer level it is estimated there will be no
negative effects on your health "
When I've read this document from EFSA
I understand that the DJA or the MRLs set by the EFSA
or JMPR were never definitive
If nothing in life is permanent
and this includes science
therefore, if there is new data that require us to change
our previous decisions then we do
Fontier Herman, Chief EFSA Pesticide Unit
So I have a EFSA document
If?
Published in January 2009 admit that change
DJA because the new data, right?
means that when the bean DJA
I thought that Protect Protect me in fact not
Failure to Protect ... no tena
not offer the same protection ...
yet ... once again ... there is a value of security applied
a value of 100 in relation the no-effect dose
therefore no security ...
that ESTN ... a bit everywhere
inserted into the system ... therefore it is unlikely
the DJA that had been previously fixed
has affected the health
Bernadette Ossendorp, Chairperson of the FAO JMPR
If you really want a zero risk, has reason
no need to use pesticides
but it is a policy decision
while politicians say they are authorized
because farmers need
to have bumper crops
it's the best we can do
"It's the best we can do"
summarizes this confession well the first part
My research where that waste comprend
of venom found in food
are controlled by a system
of Ruling arbitrary and approximate
1964 "The bread and wine of the year 2000"
Here we say that an have one uncer-tainty
Light manufacturers take all precautions
multiply the analysis
and experiences on animals
for manufacturers Food Products
is an increased workload, work expense
a waste of time are sure
all industrial Foodstuff
undertake to make a research
The question is inescapable effect
if the process of Ruling
chemi als
is based on studies provided by industry
Escog the example of food additives
emulsifiers, preservatives, colorings or sweeteners
these chemical substances
that have invaded our power supply
with the birth of the food industry
its potential danger is known
for the last 50 years
Ren Truhaut ,
Toxiclogo a consumer absorbs as
for two weeks for two months during one year or two years
can not have effects harmful
You can not have harmful effects
but you have to anticipate that these pequeas
repeated doses for long
every day over a lifetime
can sometimes take risks
extremely insidious
and sometimes an risks with irreversible
as certain dyes, for example
that at least in the animals
already checked will capable of causing
malignant proliferations ie cancer
Currently in Europe have been authorized
300 food additives including aspartame
synthesis sweetener that is found
at least 6000 products
current consumption and soda
sugar-free products called
saccharine, chewing gums
but also drugs
the number of code E951
history of aspartame is exemplary
one finds all the techniques used
industry to manipulate
Ruling process
It all started in 1965, when a researcher
of the pharmaceutical firm Searle discovered
fortuitously the molcula nine more years
later the company calls one authorization for
put it on the market to Food and Drug Administration
by the U.S. Agency for Safety
with the name of Nutrasweet
with 50 milligrams DJA
David Hattan, FDA Toxicologist
you think aspartame safe to do?
If you hink
When the FDA established the DJA aspartame
Sear e?
That's ight
November 18 1996
Press Conference on aspartame
Here is the heart of the problem
studies provided by Searle
to get aspartame homologacin
was the subject of a great polmica in years 1970
At the origin one neurologist John Olney
that we see here in a press conference
in 1996 ie 15 years after the start
in t e
aspartame market "Our article published about
"Our article is published
on the increased incidence
of brain tumors in the population
human in the United States that began
Three years after the introduction
aspartame on the market "
That you had conducted studies
about aspartame?
Dr John Olney - Neuropsychiatrist Washington University in St Louis
My first study of data 1971 which concerna
Aspartame is the combination 2 amino acids: aspartic acid
and fenil lanida.
My study showed that aspartic acid
destroys nerve cells
as does glutamate ped
after the signing Searle
that sends me a sample of
aspartame which they did, this will feed d
babies mice and watched the same brain damage
as with aspartic acid or glutamate
But if aspartame is susceptible of causing brain tumors
what is at stake in health is huge!
Because the FDA Auth aspartame?
Because the FDA did not do their job properly
In fact the way the FDA handled
to the dossier of aspartame is at least
I could see troubling internal files
of the agency through the tenacity
Betty Martini who has created a center
Betty Martini who has created a center
of documentation on aspartame
christened International Mission Possible
All the pieces accumulate conviction
obtained by Freedom of Information Act
a U.S. procedure
that allows all citizens
accessing documents of administration
As I discovered that alerted by John Olney
to assess the validity of data provided by
Finally Searle in August 1977
Dr. Bressler Jerom had a severe drafted
The report denounced irregularities all
in the studies of signature
Here is an excerpt from the reports made:
"The demands of observation confirm that the animal number A23LM
was alive at week 88
Dead Week 92 Week 104
Deaths of the week 92 to week 104
Live and dead week 108 week 112 "
then establishes a FDA commission of investigation
pblica delivering his report
the September 30, 1980
The commission concluded that "the utilization
aspartame in food
should not be authorized while the subject
its eventual potential cancergeno
has not been resolved by further studies "
November 3, 1987, Commission Senate on aspartame
The irregularities
by FDA scientists were confirmed
during the 1987 Congressional hearings
Nutrasweet, Resource Committee Senate Human
and notably by Jackqueline Verret
one agency toxicloga
Senator Howard Metzenbaum
and buds of American consumers
Dr.Jaqueline Verret, FDA toxicologist Thanks
sir Senator affirm without reservation on the amount of aspartame
now we put all the food
If we rely on these studies is a mess
from my perspective they do not have a minimum
trusted by procedural flaws in his realization that returns
hardly inte pretable
and prevent us from determining a figure quite reliable fix a DJA
David Hattan, FDA Toxicologist
"Eating can be hazardous to your health"
le pray that there will be the main page 96 and I would like to have your comments
beca se
you work here a long time is not it?
She writes: "Not that you choose by
the government is corrupt
-Is good news is not true -
but the sense of duty is constantly corrodo
by contact with industry
industry rather than the effects
long term for consumers, "
Share this constatacin you?
No, I completely disagree with it
I do not think any of us
none FDA c nsiders
do their job properly
if not will put consumer safety
above any co sideracin
by the wellness industry that equivaldraa
I am completely disagree with it
However the auditions Congress
in which I participated David Hattan
one discovers the surprising proximity
This head of the FDA and the company
Searle which was run by one of Donald Rumsfeld
1976 to 1980 the year of the election of Ronald Reagan White House Senator Howard Metzenbaum
- Demo rat
Between 1979 and 1982 four members of the FDA
having participated to
Product homologacin been recrutados by the aspartame industry
Pape, commissioner of the FDA, Shuwan Gardner
Colby Howard, deputy chief TOXICOLOGI CAL
FDA Michael Taylor and FDA lawyer
before the commission of research
No conflicts of interest are really
but m s well "revolving doors" fu
What the role of Donald Rumsfeld in the process
of homologacin of aspartame?
-Attorney James Turner, president of Citizens for Health
Donald Rumsfeld dej government when Gerald Ford
lost the presidency, after being
of the pharmaceutical firm Searle
The company was installed in the represented circunscripcin
when elected to Congress fu
the Searle family was very influential
and all had sustained during their political career
for which he was recruited by Searle
After the election of Ronald Reagan
After the election of Ronald Reagan
Rumsfeld uni transition team
the new president and who is the controlling
the nomination of the new FDA commissioner
once installed, the new commissioner dispos
Scientists working in the FDA
and declared that aspartame tena no danger
Donald Rumsfeld
When I get a mission
I do the best I can
I have here as after a few weeks
the election of Ronald Reagan
aspartame invaded the American market
as soon as if by magic
the decision of the FDA copied fu
across the Atlantic
"NutraSweet because many things
taste very nice "
Geneva, Switzerland
Rencontr in WHO JECFA files
the Joint Committee for Food Additives
All you discover that from 1975 to 1979
for aspartame while the FDA
For example 1978 report notes that "reason
expressed doubts about the validity of the data
Deferred application the committee based its decision n "
Changing weather report 1980
where the experts decide to fix the DJA
aspartame 40 milligrams per kilo
In the annex of the report adds
is the name studies
which is based this decision:
The DJA set by the JECFA was adopted
with eyes closed
by European countries and particularly by the European Food Safety Authority EFSA
for the Safety of Food
Huges Koenigswald, Head of Unit Food Additive
This EFSA DJA 40 milligrams per kilo was established at the beginning by the JECFA
is the group of international experts
FAO and WHO in 1980 fu
then the same DJA
is established by the committee of scientists to human power supply
so for Europe, 1985
Fu WHO, hoje files in
and the JECFA had access to documents files
this is very disturbing first 40 milligrams DJA
is based on a study highly controversial and jams
this is came back on, once again
studies beginning are highly objectionable
I is not have to think about studying
initial'm not the elements to judge
more than I can read evaluations preceding
and evaluations mentioned above that s
, and bean doubt that this bean is removed
S, but no files
new studies to explain why this doubt quit
About something actually did thirty years ago
may be regrettable, it is often the case
Senate Commission on Aspartame
O-Ohio Senator Howard Metzenbaum
While waiting, the effect "snowball"
is a bargain for industry
is what the evidence shows
Robert Shapiro CEO of Nutrasweet
subsidiary Searle, which -Searle-fu purchased
by Monsanto in 1985, who will verify
Robert Shapiro, CEO of Nutrasweet
Those who attack aspartame
health and regulatory world
The fact that all organisms scientists
health or
Ruling in USA and around the world
who have examined the data
aspartame safety have all
conclusion: no aspartame danger
David Hattan, FDA Toxiclogo
The FDA has received many complaints on aspartame have here
list harmful effects became public
there are many harmful effects 92 complaints in total and many hundreds of thousands
Complaint headaches, vrtigos
epilepsies crisis
vomiting, vision problems
Do you think this is disturbing list?
In fact, the FDA and the firm Searle
that manufactures aspartame led clnicos
additional studies to evaluate these effects
as headaches or seizures epilepsy
all this been carefully tested
and the result was that in an environment controlled
and when you know exactly the dose used
the very moment of the individual ingestiny
that consumes one does not get
to replicate or reproduce these effects
Dr John Olney - UW Neuropsychiatrist St-Louis
According to all my knowledge
Searle jamsa appropriate studies conducted
to determine whether aspartame causes
problems in the central nervous system
November 18 1996
November 18, 1996
Press conference on aspartame
Dr. Ralph Walton, Psychiatrist
Buenos das, for the last 12 years
my patients ensearon me that aspartame
Pruning cause a large number of problems
on vulnerable populations
can cause epilepsy depression, panic
I have discussed the scientific research international on aspartame
cientficas serious concernan clearly that
Product safety on human
About 164 studies 74 were established by the aspartame industry
74 say that aspartame is not danger
Ralph Walton, sychiatrist
bean one correlation hundred percent
between the results of the studies and orgen financing
between the results of studies and financing orgen
all studies funded by the aspartame industry concluan
did not cause any trouble and one hundred percent
truly studies independent
concluan that had one problem with substance
How do you explain it?
Tragically money is very powerful
The argument is serious This suggests that
that scientists can be purchased
To be sure, touch doors
of a prestigious institution American Cancer Society
which just tie with industry is often denounced
Dr. Michael Thun, epidemiologist Former President of American Cancer Society
It is absolutely true that industrial
which may be affected by studies that affect their interests
attempt to influence the view favored the public and politicians
trying to influence times in investigations
Dr. Peter Infante, epidemiologist
is a fact that no well-conducted studies
and frightening studies and often
studies are funded
indus ry
are designed such that it is completely impossible
detect harmful effects, that means
which is the scientific literature
regularly contaminated studies
regularly contaminated by studies
facts are not conveniently
Dr. Michael Thun, epidemiologist
It would be a good idea if the scientists
that evaluate drugs are not given
money from firms farmacuticas
or those working on products
contaminants were paid
for those who manufacture
But that is not the case
No, the reverse is a common practice
Yes, I worked in a
Ruling agency for over twenty five years
if they can not beat you on the ground
science then resort to personal attacks
, this experiment myself
They wanted me fired from my job
and the reason precisely that fu
because I was doing my work
Unfortunately it is very common
you are asked to
government agents who change their interpretation of the
data they deem as unreliable
most of the time is very difficult in reason
of
economic situation of those scientists who are
there in 1 hour and 50 minutes wish them good ...
There in 1 hour and 50 minutes wish you a good ...
Unfortunately centers are rare
totally independent investigation
that ESTN protected from Industry pressure
is the case of the Foundation European Ramazzini
specialized private institution
in environmental cancerologa
Its researchers have conducted two studies on aspartame
published in 2005
The first was done with rats 1800
that a dose of aspartame ingerieron
near the DJA from the age of 8 weeks
until the age of natural death
Result: increased lymphomas significant
and leukemias in females
The second study was 400 females are preadas
microns which were followed until death
This result confirm the first study
which adds a significant increase
interestingly these two studies
were rejected by the FDA and EFSA
Dr Morando Soffritti, Director of the Ramazzini Institute scientist
Based on our data safely
is cancergeno for animal experiments
Hugues Koenigswald, Head of Unit Food Additives EFSA
There is certainly by no mean certain failure
There is certainly not mean certain failure
metodolgica on purpose these studies
For example?
Well, in particular Rats that
that were under study had
much of respiratory pathologies
Dr Morando Soffritti, Director Scientist of the Ramazzini Institute
We agree for a number of reasons
firstly, because the inflammatory process
we observe in our animals depend
often the fact that we
let them die naturally
without interrupting your life arbitrarily
and as is the case in man in the last phase of his life
pulmonary complications
and kidney are common
is very common to find inflammations
both the lungs and kidney
Respiratory disease is the
origin of the tumor and therefore can erase the tracks
is exactly what happened in this study
The rats in the control group Tenan the same breathing problem?
Dr Morando Soffritti, Director of the Ramazzini Institute scientist
Of course, the observed habamos
together in the treated group and the control group
The only difference between the two groups was that the group experienced
had ingested aspartame and control group that had not ingested Koenigswald
Hughes, Head of Unit Food Additive
EFSA Anyway most of
results of these studies have been
analysis invalidated by doing
committee of experts of the EFSA
In fact the arguments of the EFSA
really did not convince me, they intrigued
investigu for know who the 21
Member of the Committee of Food Additives EFSA
from a recent date, each expert
must declare their conflicts of interest
and the declaration can be consulted on the website of EFSA
We discovered that John Christian as the President of Larsen
Committee works to institute funded ILSI
by multinational agribusiness and qumicas
or Jrgen Knig tena contract with Danone
or even that Dominique Parent-Massin working
for Aji No Moto japons one of the leading manufacturers of aspartame
or
Coca Cola a big user of aspartame
I've checked all 21 members Committee on Food Additives
Ye
I saw Dominique arent-Massain
who is member of the working scientist Manufacturer
Aspartame the Japanese Aji No Moto
then, here's a real conflict of interest
This means that when we did the evaluation ...
this expert can not be
rapporteur to prepare the advice of the group and can not participate
on this issue because dliberacin
there is a conflict of interest
and here for example in the case of the board
was done on aspartame 2009
Dominique Parent-Massain did not participate?
No, its declaration of interest was evaluated
limit she does not participate in certain activities
of EFSA in relation
aspartame, in Addition to the process
habamos we set for
do the evaluation of the declaration of interest
the declaration of interest
Transparency in all cases limited
the declaration of interest of Dominique Parent-Massain
I had found on the site of the EFSA
before conducting my interviews
da are gone today and you replaced ESTN
a new one, where experts say no
a word about this Aji No Moto relationship with
and Coca Cola, strange coincidence
A senior leader of the EFSA told me one day:
"Dr. Soffritti, if we admit
results of their studies are vlidos
deberamos ban aspartame from early morning
you realize that's not possible? "
Pr Professor Erik Millstone Policy How Cientfica University of Switzerland
If they admit they made a mistake that llevaraa
lose confidence therefore, they fear doubtless
that may open the floodgates
hiciero you not a single
but some errors and can be all
the process defective
"can be the whole process is flawed "
At this stage in my research I understood
the entire system of products Ruling
chemicals is controlled by
industry whose main preocupacin health is not
consumer research but
1960 "Bread and wine of the year 2000"
for example, raises many concerns and
is sold in plastic bottles oil or wine
is uncertain whether regression
is enough to decide that the remains of plastic
that necessarily happens in oil
necessarily happens in the oil
or wine are not harmful
Invented over a century ago
the plastic has been imposed on all
domains of life the electronic equipment
clothing, transport media
furniture, toys, utensils
cooking or conditioning
food product
is estimated that every European uses an average
92 kilos of plastic per year
40% comes from food packaging
An example Bisphenol-A, called GAP
whose annual production amounts to 3 million
tonnes, is found in products
in polycarbonates as Bibern
water cylinders
microwave preparations
but also in the resins used
as coatings in containers
Allowable laborer Dose
of bisphenol A was set
0.05 milligrams per kilogram of body weight
The plastic is present everywhere
is present the world announces ma ana
Sern our children of this world
and grandchildren not to vern
For a long time been considered the
inactive-that is unfortunately inert-
this is not the case which is
fortuitously discovered Ana Soto and Carlos Sonnengstain
two researchers in cell biology
Boston Un versity
In 1997 they worked on cells from c
breast cancer experiment consists cause
to Estrogen natural female hormone
Control tubes were kept in plastic
Pr Ana Soto - biloga Tufts University Cell Boston
We constantly repetamos it
result, in the absence of Estrogen
of cancer of the cells did not multiply within
but in the presence of Estrogen
multiplied them and suddenly all
c cells began to multiply
indiscrim nately
We think that one
habamos had contamination by Estrogen
finally we found that the activity
Provena tube in
which we retained tissue culture
then call the manufacturer of the pipe
quin could not give us the explanation
we sent several magnifiers
the Estrogen that was done due to change
due to the plastic formulacin
Pr Carlos Sonnenschein - Cell Bilogo Tufts University Boston
for this reason Rehus reveal the composition of
therefore it is thanks to our research
independent that we identify
the substance was nonylphenol
The nonylphenol as bisphenol A
hormone synthesis are used as antioxidants
in
the plastics materials after its discovery
the two researchers decided to focus on BPA
in reason of its massive utilization in food plastics
to
observe the effects on the second generation
Here the mammary gland of a mouse 4 months
we can see the tubes that later
will be providing milk, are not as numerous
and have few branches
now show you an animal that has been exposed to bisphenol A
in the uterus, we can see the complexity
conduits and branches
is four months after the exhibition
this will be a situation normal if the coffee
at this age an animal should be as normal
therefore there is a significant difference
pregnancy is not a pathology
if the female is preada
but if the mammary gland of a female
that is not mimic pregnancy preada
then that is not normal
What is the dose of bisphenol A that administered?
250 nanograms per kilo
is a very low dose
A 200-fold lower than the dose DJA
The story of Ana Soto and Carlos Sonnenschein of
U.S
chronicle in 1997 was published in France under the title
"Man under threat of disappearance"
is the result of research
conducted by Professor Theo Colborn
she has studied the impact
of the chemical contamination
on the fauna of the Great Lakes
then she realiz
the synthesis of a thousand studies related to
evolu ion
certain wild species such as gulls
whales or otters
a real job etective
which led to the creation of a new
scientific concept of those
"Disruptors En ocrinianos"
Pr Theo Colborn - Zoologist environmental health expert
I began with identifying all these problems
observed in these different species
general adult animals
They seemed normal and when pruned pequeos-
reproduce, and when Haban pequeos-
not reached adulthood
if they succeeded not live long
and were unable to reproduce
You will be able to tell us that is a disturbing endocriniano?
The answer is very simple
chemistry is a substance cul
endocriniano doing endocriniano system?
Basically allows to reproduce the
allows us to function normally
the controls the entire construction process
of a baby, from fecundacin
until birth, each msculo
the programming of the brain or all
the organs all depend
This endocriniano system
The problem is that we created
chemicals that resemble
to natural hormones and can
enter the same receptor activating a
funcino Off ndola
ms hormones and that's the problem
The term "Troublemaker Endocriniano"
fu invented during the middle of
Winspread conferences organized
by Theo Colborn in 1991
All brings together twenty scientists
that fueled his book after
it meets every year in a colloquium
in New Orleans, all ESTN Ana Soto and Carlos Sonnenschein
Louis Guillette specialist crocodile
Fred Vom Saal who works from over twenty years ago BPA
or John McLachlan, specialist distilbeno
or John McLachlan, specialist distilbeno
DES in english, banned for the last 30 years
this drug widely prescribed
to prevent miscarriages
is considered the model
of disturbing endocrinianos
because the case is unique, not only
because the available test data
on animals but also
epidemiolgicos data of human
chemist has changed our way of thinking
aclarndonos what is
the endocriniana perturbacin and that
we now call da fetal orgen
of the adult diseases
If you go back 60 years
distilbeno ATRS the first hormone fu
of synthesis invented by Charlie Dodds in 1938, had already
synthesized bisphenol A 1936
as an Estrogen, the distilbeno
has been used as a support endocriniano
pregn ncy
has been prescribed to more than 4 million women
U.S
in the end of the years 1940 to 1975
AFTER s you know all the history
is found cnceres cervical
- Bilogo Tulane University New Orleans
I had observed when exposed to
mice on gestation to distilbeno?
Note effects on offspring in
cnceres on your system
reproduction particularly in the vagina as the case is human
in fact all you have found
in mice has been verified in humans
and all that has been in humans has also been verified in
mic
It is very disturbing when we discovered what
habamos noticed that females
second generation Tenan one more early menopause
and 25 years later we find
the same thing in women who were exposed
So must repeat again and again
all the consequences of distilbeno
observed in human have been also
in mice and rats
and with Carlos da today we got the same
results dbiles doses of bisphenol A
similar to what we found in the environment
and in this point there is a difference
and if you we parallels with distilbeno
that means it was not until the 2032
to check on humans
So be very difficult because
distilbeno for women who have been exposed in utero
while women that They will have a c
cancer in 2032 they will have no
any evidence that they were exposed to BPA at uterus
I leave you with this very disturbing thought
of Biology, University of Missouri
Fred Vom Saal Pr - Bilogo University of Missouri, Columbia
The chemical industry has done a tremendous job
of disinformation to convince people
we are not exposed to bisphenol A
and the q antity
found in our bodies are not at all worrying
an example if you have your dose
an example if you have your dose
BPA everyday just enough eat Heinz ketchup
the same thing for the substances
containing lipophilic as oil atn
the Center for Disease Control
has made various studies to measure the level
BPA in urine and as we can
see in this national research
ms are as young, the higher the level of BPA
That observ effects when exposed
mice on gestation
very debles dose of BPA?
Studies on animals show
that high doses below the
Allowable Dose laborer causes secrecin
insulin, increased glucose rate
insulin resistance, diabetes
Heart Disease dysfunctions
brain and problems behavior
We also find
male and female
uterine fibroids, in
malformations of male testicles, reduced sperm
amount, growth hormones
and abnormally low testosterone
finally, observe the prstata cnceres
in males, breast in females
Roselyne Bachelot, Minister of Health and Sports France
The principle of precaution only applies
in the absence of reliable and in studies
this occasion reliable studies exist
and they conclude that in the present state of science
is given the safety of baby bottles with bisphenol A
For several years bisphenol A
is the subject of a fierce struggle
that precludes agencies of Ruling
and a number Scientists crescent
what is involved is not only DJA
set but all the way are evaluated
disturbing en ocrinianos
in which the BPA has become the symbol
audition in the National Assembly
in the heart of the conflict the "
Effects of Dose Dbiles" that toxiclogos
indus ry
ignore and which do not test
Interestingly agencies of Ruling
Interestingly agencies of Ruling
continan basing their assessments
industry studies whose quality is controversial
Regarding industrial they cling
keeping the status quo the same argument
manufacturers like aspartame
as here in the audition organized
francs in parliament
Michel Loubry, Director Europe West PlasticEurope
throughout the world to present that
industrial we need
know what you think
health agencies that we authorize to market different products
The current consensus
of the five health agencies
United States, Canada, Europe and Japan
is the current level of exposure
of BPA in food application
of the population this includes to children and babies
Andr Cicoletta, alchemist Toxiclogo Spokesman Environment and Health Network
When I heard his speech and you say
all agencies agree
I say, all agencies agreed
to say that asbestos caused no
where is n the victims?
The victims already dead ESTN 3000
then the real question
that one asks is: you have to wait 40
50 or 60 years to have the certainty?
Or is that from what we know
this convergence of animal studies
in the monkey, the data in monkeys
are extremely strong I think
Principle of Caution prevails
Principle of Caution prevails
Briant Pascale, Director of the Agency AFSSA French Healthcare Food Safety
The problem is we can not protect
appropriately to our citizens
based on the emotion
that does not mean therefore that
His words are sense at this time
as you talk about emotion versus
to all scientific data?
It is true that the word "emotion" is
surprising after 10 years in effect
the effects of BPA at doses
very dbiles sometimes
five thousand times less than the DJA
is what supports the
Declaration of consensus signed in 2007 by 38 international scientists
under the auspices of the Institute National Science
Environmental Health of the United States
Carlos Sonnenschein, Ana Soto or
Linda Birnmbauem the new director of NIEHS
They write: "The pathologies
current human resemble the effects observed
to laboratory animals exposed
a very dbiles dose of BPA
as increased breast cancer and prstata
, the diabetes type 2, obesity
or behavioral problems such as hyperactivity
Linda Birnmbaum, Director of NIEHS. National Institute of Environmental Health Sciences
Do you think that the BPA
should be prohibited at least in the bottles as they did
lately in Canada?
I am pragmtica, I think there's enough
Pragmtica I am, I think that sufficient
evidence that BPA has
the potential to cause adverse effects
particularly in certain periods
very sensitive to human development
therefore, if I were a young mam
and if my baby fed with Bibern
I would not want to have BPA in their Bibern
As you explain EFSA or the Authority
European Agency for Safety Food cling
DJA to 50 micro grams per kilo?
Because they have not examined the new data
that's the problem, some Ruling agencies
They are very slow to adapt to the new science
Fred Vom Saal Pr - Bilogo University of Missouri, Columbia
Basically we say
the calculation process est of DJA based
false hypothesis dating from the sixteenth century
does not take into account the fact
that chemicals react as hormones
and still no hormones toxicologist rules
Alexandre Feigenbaum Chief Unit of EFSA CEF
Fifteen years ago the lord Fred Vom Saal
tries to convince the scientific community
taking into account their studies, not convinced
to the scientific community and most
that are responsible for the evaluation of risk
either the FDA, either in New Zealand or Japan
, BFR in Germany or the FSA in England
Everybody is in agreement with our Gestin
of the risk evaluation and the DJA oms
While DJT DJT: Dose laborer we have established Tolerable
dose effect does not work
Pr Fred vom Saal - Bilogo Columbia University of Missouri
The principle of dose-effect relationship
which is the corollary that "the dose makes the poison
" is completely errneo
this can work for some
but not for any hormone hormones to
to certain hemicals
and for the natural hormones know that
"dbiles dose" can stimulate
while the strong dose inhibit
while strong doses inhibit
dose for hormones never makes the poison
the effects do not worsen systematically
linear curve in Endocrinology
dose effect does not exist
Alexandre Feigenbaum Chief Unit of EFSA CEF
Indeed if one finds scientists
ranging in that studies
supporters of the effect "dose dbiles"
It is an ideology According you "supporters"
means is no cientist?
I do not know, you may think that one
based view favored one has a greater impact on the
hypothesis or unconfirmed? is not possible
To be frank, the response
more modern twis Once the doors
American Association of Cncer whose conservatism
is often criticized but
is a reality established cientfica
a new way to control Products chemicals?
Dr. Michael Thun, epidemiologist Former Vice President American Association of Cncer
is definitely evident for many reasons
First, because there are all
these very interesting research
about "dose effect dbiles"
and for certain types of chemical substances
in particular those having
estrognicos effects numerous studies
showing that there are effects at doses
extremely dbiles, therefore
whole p ocess
determines everything which is reproducible or
are the implications for cancer
are the implications for cancer
It is brand new and second
Principle of Caution seems to have
sense if there is a potential problem
better react immediately to prevent
"Best reacting to prevent"
It means that everything is done
indeed disturbing endocrinianos
represent a large family regrouping
the plastics components
dioxins, PCBs, Teflon
of non-stick pans, food additives
, but also numerous pesticides
All of these products are
a "dbiles dose" in our power supply
and these "dbiles dose" jams have been tested
the same way is not proved possible
Sinerga between residues of different products qu
monkeys that pollute eg
grapes analyzed in this laboratory german
In June 2009, EFSA published its first annual report
about pesticide residues
75,000 products were tested in the 27 countries of the Union
European, were detected in total
350 pesticides in fruits and vegetables
and 72 Grains in a room
sample is received by at least two pesticides
Can they interact? With what effects?
is what is called the "cocktail effect"
The question of the cocktail effect is very relevant
all we have
chemistry body burden in english: Chemical Body Burden
is the revealed that the Center for Disease Control Disease
Atla ta
wearer from ten years ago a program of Bio Monitoring
where measured traces of the chemicals
in the blood and urine of volunteers
In the fourth report published in 2009
was e
212 substances were found in almost all Americans in 2400 test
In the head and numerous bisphenol A
Linda Birnmbauem pesticides, Director NIEHS
in our studies, interesndonos
on a single product at a time chemist
while none of us
is exposed to a substance only
when we are interested only
to a substance and ignore the other
I think we can err
fully discover the effects that occur will be able to
Copenage enmark
Rare are laboratories working
on the cocktail effect one among them
is part of the University of Copenage
toxicologist Ulla Haas has proven
Toxicologist Ulla Haas has proven
the mixture of three substances qumicas
considered antiendrgenos
ie affecting production
of testosterone, the hormone needed
development of males, including
procymidone fungicide recently
re evaluated by JMPR experts
The fu mixture administered to rats
in gestation and effects medan
The results are very disturbing
Take for xample
Ulla Haas, Toxicloga, National Institute of Alimentacin -
Copenhagen is the distance between year and genital part
of the animal, it is twice as long
in the male than in the female, is due
at endrgeno role during development
of the fetal stage, which ms is short
in the male is an indicator that there is a
severe hypospadias congenital malformacin
of the male organs of reproduction
When habamos tested each product separately
habamos he found no
any effect or any malformacin
and when we exposed the male fetus
to a mixture of three substances
note that 60% of them have
pruning later one hypospadias also
malformacin serious in their sexual organs
working on the toxicologist mixtures
because our results say:
zero zero zero mas mas ago 60% of malformations
It's scary what you say above
when we know that every European has
what we call a body load limit
what we observed in rats may
what we observed in rats may
also occur in our bodies?
In fact the big problem is that we know nothing
It is difficult to understand why this
has not been taken into account soon
When you go to the pharmacy to buy drugs
all written in the instructions for use
you have to be careful if one takes
therefore Drug
is very clear that there may be
a combination of effects if one takes
several drugs at the same time
That's why it is not so surprising
we are ahead of the same phenomenon
contaminants chemicals
Everything indicates that the system of Ruling
of chemicals is
at a crucial time and be redone completely
Dbiles effect dose sensitivity particular fetus cocktail effect
while the chronic diseases
do not stop in progress
called developed countries, whose head is the cancer
whose incidence has been multiplied by two
in the course of the last 30 years
According to CIRC figures
As you can even deny
these diseases are linked to the industrial model that characterizes
to modern civilization ?
Christhope Wild, Director of IARC, International Research Center
When the Cncer retrieve its website
and the maps of the cancer is found
that this disease is present above
in the countries called "developed"
for example if we take the breast cancer
in red are the regions where the incidence
is more elevated, is in North Amrica
ms is high, it is in North Amrica
Western Europe, Australia and some in South Amrica
It's the same thing for cancer of the prstata
cancer of the testicles, leukemia
cancer of the brain, thyroid, pulmn
What we know is that between
80% to 90% of the cnceres are due
on lifestyle and environmen
is what studies show
of persons migrate from one region to another
they adopt to put it as
type of cancer in the region where they are installed
in the process of passing the risk factors that lead
to ca cer
of the rich countries to the poorer nations like
weight o erload
obesity, lack of physical activity
It is because these countries adopt our way of life?
If it is because of the change of lifestyle
is foolish, that poisons over da one knows
For me there is no other means of solution for live
in good health to eat right there
The environment and lifestyle
here I have the two main causes of the explosion
of the chronic diseases, of which
the Obesity is the most visible sign
according to official sources 70%
of the U.S. opulation
is overloaded with weight
I could shoot these images being twenty minute
in a supermarket in Houston
In the world of research two schools
ignored while all indicates
that are complementary of one hand researchers who work exclusively
on the environmental origins of chronic diseases
ie the effects of the chemical contamination
the other side are the scientists
who care life style and especially the consequences
Junk ood
based in an excess of fat intake
and sugars and a lack of plant products
Professor at the University of Qubec Richard Bliveau
is
master of thought of the second School, author of over 230
the second school, author of more than 230
publications in journals international medically-
the leads a team of 30 researchers
working on prevention
and treatment of cancer
Pr Richard Bliveau - biochemist University of Qubec
One of the consequences of using
Junk food and industrially processed products
omega-3 molecules generated
anti inflammatory omega-6 molecules generate pro-inflammatory type
a ratio of 1/1 and consumed is farmer or rancher hunter in our history
spent one has a ratio of 1/1
With the industrialization of mostly junk food
that is used contains only omega 6, therefore
fats that come from industry
junk f od,
of the transformation industry are fats that lead to metablico level
an omega 6 omega 3 ratio 25/1
When consumed the feed industry
one gets metabolically fisiolgicamente
and pro-inflammatory mode
in effect orgen of cancer there is always one
one clul attacked by an outside agent
which can be a virus, a chemist product irradiacino a
if the body is in good health
the daada clul is detected by
the NK lymphocyte english "natural killer" natural murderer
that pushes suicide
is what we call apoptosis
n chronicle and aggression
by a chronic inflammation and aggression
standing of chemical agents
apoptosis fails and defective clul
begins to multiply
It is the beginning of tumor that to develop
needs to be nurtured by the network sangunea
this phenomenon is called angiognesis
to the angiognesis trmino leads to creaccin
of metastasis, ie the colonization
cancerous organism by clul
In certain vegetables we eat
one called fruits and vegetables
molecules is also
that pharmacologically have the same effect
certain drugs chemotherapeutic
Some of these molecules are citotxicos
These molecules kill cancer
Some of these molecules are pro-apoptotic
ie they induce clul the cancer to suicide
Some of these molecules are anti inflammatory
they block the inflammation the cancerous clul
need to encourage their development
Then, as is that measure the potential
of inhibicin of a food?
well, we do a bank tumors, human tumors
we can buy and this is the cancer
glioblastoma, cancer of brain we do
grown for 24 to 48 hours
counts the number of cells that have divided
then were exposed to various extracts
food, here we Cherries
carrots, which shows that there is no
inhibicin much but then when
one goes with the garlic, cabbage or brussels
found in cranberry inhibicin 90%
a glioblastoma, when one isolated
these foods when create a cocktail
super anti cancer foods
if you take a mouse which we implant
a human cancer
here is a mouse that has been fed
with mouse chow
Here we take the same mouse
when one is by mouth with cocktail
food the most anticncer we found
in this test well in vitro and have
a reduction of 90%
tumor mass
Gradually I finished assembling
all the pieces of the puzzle
to outline a coherent set
The epidemic of chronic diseases
observed in the world Western is due
to contamination chemistry and particularly
the mode of transformation of production mode
our food where effects
of revolution agrcola and agrifood
combine to form a explosive cocktail
An example: India, according to the CIRC
20 the incidence of the most common cnceres
in the state of Orissa in the south west pas
the cnceres are almost nonexistent to the exception of that
mouth due to masticacin
of snuff in this very rural region is ignored
essentially namely fruits and vegetables
produce grown without pesticides they consume daily
turmeric, the yellow powder that forms the basis of curry
known since the dawn of time
its anti inflammatory, so I
anticancergeno have been confirmed in more than 3000 scientific publications
I do with urmeric?
Make a curry and then eats or applies
on the body everything is good
you can mix in a glass of water every morning
and a dozen microbes morirn
and will not have the skin irritations
or chickenpox, is very good for all
disea e,
cows can eat men can eat goats can eat
the cat can eat
There are obese people in his village?
In the village is my nephew who is the fattest
is one of the most fat people
But he is not obese
All there is even a little fat person
There are people who cancer have in town?
No, o
know what is cancer?
The cancer? is a disease?
When the person reaches the body
dies in 3 6 months
Not far at all Bhubaneswar, the capital
Not far at all Bhubaneswar, the capital
Orissa Society of India Cncer has a symposium of
International in collaboration with the Institute
Anderson of Houston, one of the most large
research centers of cancer in the world
The theme of this third edition is called
"Cncer and inflammation" They speak of course
specificity of India that is
in the process of disappearing particularly
in the state of Punjab the cradle of the Revolution
Green but also of large metropolos
mode is adopted where Western life
Prof. Arvind Chaturvedi, Director of Research Institute in New Delhi
During my exposure to them talk of evolution
world of cancer, in the Western world
the cancer that has the highest prevalence
it is for the woman breast
and for the man prstata
life of our country
where the incidence of the disease is increasing
is not even as high as in Western countries
but will increase in reason change
the lifestyle and food habits
If we do not take into account the lesson
to pay a very high price, the answer is simple
no chemicals ontaminants
is simply not the polluting chemicals
not processed food
a healthy life with biological food
no red meat alcohol, snuff
smoking or chewing etc.
"Let your food be your remedy and your medicine your food "
Postscript
Jean-Charles Bocquet, Director of UIPP Union of Industries of Plant Protection
If good morning, Marie-Monique Robin I made a request for an interview
You Rehus, but everyone wanted to be sure anyway of opinion did not change
Well, no change of opinion
Phil Newton, European Association of Pesticide Industry
I Sorry, but our position will not change
Thomas Lyall, Dow AgroSciences
We want to work on something really
In a written response and subtitling francs to espaol by Marisol Paredes Silva Guenot
Yannick Chenet (14:59) quin has testified in this film, I died in January 2011
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