All language subtitles for Silent Witness - 24x06 - Reputations, Part 2.720p.ORGANiC.English.C.updated.Addic7ed.com

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Would you like to inspect the original subtitles? These are the user uploaded subtitles that are being translated: 1 00:00:00,000 --> 00:00:03,159 Victim is Mr Arnie Rahul. Consultant surgeon. 48 years of age. 2 00:00:03,160 --> 00:00:06,039 Good reputation, though he's fallen out with a few people recently. 3 00:00:06,040 --> 00:00:08,655 He was about to start an operation. He gets a phone call. 4 00:00:08,680 --> 00:00:10,919 Walks out, never comes back. 5 00:00:10,920 --> 00:00:13,580 Single puncture wound to the left chest wall. 6 00:00:15,040 --> 00:00:17,839 - What's that in his hand? - Looks like a syringe and needle. 7 00:00:17,840 --> 00:00:21,079 It's a Hickman line. A long-term vascular access device 8 00:00:21,080 --> 00:00:23,599 for people who need chemotherapy or blood transfusions. 9 00:00:23,600 --> 00:00:26,319 The assailant would have had extensive cross contamination 10 00:00:26,320 --> 00:00:27,799 with the victim's blood. 11 00:00:27,800 --> 00:00:29,959 Stick that in to a big artery and blood will flow out 12 00:00:29,960 --> 00:00:31,519 like a high-pressure hose. 13 00:00:31,520 --> 00:00:33,120 Simi Jacobs. 14 00:00:33,960 --> 00:00:35,320 He's denying everything. 15 00:00:36,400 --> 00:00:39,639 Simi Jacobs is not a match 16 00:00:39,640 --> 00:00:41,279 to the blood spatter at the scene. 17 00:00:41,280 --> 00:00:43,559 So, who is it? It's Wilfred Okoye. 18 00:00:43,560 --> 00:00:44,679 The patient? 19 00:00:44,680 --> 00:00:48,439 Arnie Rahul was murdered by a man who was under general anaesthetic 20 00:00:48,440 --> 00:00:49,839 in a different room? 21 00:00:49,840 --> 00:00:53,479 Blood alcohol level, three times the legal driving limit. 22 00:00:53,480 --> 00:00:55,799 You said he shouldn't be operating. 23 00:00:55,800 --> 00:00:57,799 Not after the Harry Fletcher incident. 24 00:00:57,800 --> 00:01:00,719 Arrested on the table during surgery last week. 25 00:01:00,720 --> 00:01:03,359 I want you to do the postmortem. 26 00:01:03,360 --> 00:01:05,559 Technically that would be a conflict of interest. 27 00:01:05,560 --> 00:01:08,839 Summarising postmortem examination, Harry Fletcher. 28 00:01:08,840 --> 00:01:10,759 What are you doing? My colleagues are here. 29 00:01:10,760 --> 00:01:13,719 - Is that Emily Braithwaite? - She's Adam's godmother. 30 00:01:13,720 --> 00:01:15,839 You'd think he might have mentioned it. 31 00:01:15,840 --> 00:01:18,359 - Are you going to confront him? - Not yet. 32 00:01:18,360 --> 00:01:20,799 Your original stem cell work was brilliant. 33 00:01:20,800 --> 00:01:24,679 But you tried and failed to turn it into a viable cancer treatment. 34 00:01:24,680 --> 00:01:27,239 Wilfred Okoye, still in the hospital. 35 00:01:27,240 --> 00:01:28,919 What's he going to know? 36 00:01:28,920 --> 00:01:31,879 You won't find out unless you ask him. 37 00:01:31,880 --> 00:01:34,759 Mr Fletcher died because of surgical error. 38 00:01:34,760 --> 00:01:38,319 Adam! You have no idea what you've done. 39 00:01:38,320 --> 00:01:40,839 When I applied for this job I falsified my CV, 40 00:01:40,840 --> 00:01:42,719 and Emily Braithwaite tried to use this 41 00:01:42,720 --> 00:01:44,999 fact to influence my findings in the Fletcher Case. 42 00:01:45,000 --> 00:01:46,679 Here's my letter of resignation. 43 00:01:46,680 --> 00:01:47,960 Effective immediately. 44 00:02:37,295 --> 00:02:41,215 Wilfred Okoye, a Beninese farm worker, was admitted 45 00:02:41,240 --> 00:02:45,039 to St Jude's hospital for the treatment of leukaemia a week ago. 46 00:02:45,040 --> 00:02:48,615 Although he lost consciousness briefly during the attack 47 00:02:48,640 --> 00:02:52,319 on his life last night, he seems to have recovered with no ill effects. 48 00:02:52,320 --> 00:02:56,639 Awaiting toxicology from the syringe we believe was used in the attack. 49 00:02:56,640 --> 00:02:58,039 Prints? Fibres? 50 00:02:58,040 --> 00:03:00,679 - Nothing conclusive. - We're interviewing witnesses 51 00:03:00,680 --> 00:03:02,639 but no-one got a good look at the attacker. 52 00:03:02,640 --> 00:03:05,159 How come he's being treated here in the UK? 53 00:03:05,160 --> 00:03:09,000 It was set up by a charity, and then arranged through Rahul. 54 00:03:10,600 --> 00:03:15,055 Here is a man who has lived his entire life in Benin 55 00:03:15,080 --> 00:03:19,119 up until a week ago, and, according to our DNA evidence, 56 00:03:19,120 --> 00:03:23,400 murders his surgeon while under anaesthetic in a different room. 57 00:03:26,642 --> 00:03:32,599 Could the DNA at the murder scene been a contaminant or planted? 58 00:03:32,600 --> 00:03:35,079 No. The spatter patterns are too perfect. 59 00:03:35,080 --> 00:03:37,719 It came from someone who was in the room at the time. 60 00:03:37,720 --> 00:03:39,360 So, how do you explain it? 61 00:03:42,680 --> 00:03:45,759 How do we know Wilfred was anaesthetised? 62 00:03:45,760 --> 00:03:48,439 I mean, how do we know it was him? 63 00:03:48,440 --> 00:03:50,199 What, he's got an identical twin? 64 00:03:50,200 --> 00:03:51,679 Bit fantastical, Steve. 65 00:03:51,680 --> 00:03:52,880 I don't know. 66 00:03:53,520 --> 00:03:55,120 There's another explanation. 67 00:03:57,036 --> 00:03:59,156 DNA samples got mixed up. 68 00:03:59,295 --> 00:04:01,079 Ah! No way! 69 00:04:01,080 --> 00:04:02,960 Look, I'm just putting it out there. 70 00:04:02,984 --> 00:04:04,496 - Mm-mn. - We could run the test again. 71 00:04:04,520 --> 00:04:06,520 Those samples were handled correctly. 72 00:04:07,960 --> 00:04:10,258 Jack, shall we just run them again? 73 00:04:13,440 --> 00:04:15,200 Right, yep. Good. 74 00:04:16,440 --> 00:04:17,480 OK. 75 00:04:18,469 --> 00:04:20,600 Let me know when toxicology comes back. 76 00:04:28,647 --> 00:04:31,720 So, the samples got mixed up, 77 00:04:31,744 --> 00:04:32,991 - did they? - It's always possible. 78 00:04:33,016 --> 00:04:34,056 Mm-hm. 79 00:04:34,291 --> 00:04:37,913 You know who took the swab from Simi Jacobs. Adam. 80 00:04:38,929 --> 00:04:40,440 What are you suggesting? 81 00:04:42,331 --> 00:04:43,811 Just saying. 82 00:04:52,720 --> 00:04:54,519 You have reached Dr Adam Yuen. 83 00:04:54,520 --> 00:04:56,119 I am unable to take your call. 84 00:04:56,120 --> 00:04:58,080 Please leave a message after the tone. 85 00:05:00,880 --> 00:05:02,920 Do you know what I don't understand? 86 00:05:03,260 --> 00:05:05,639 It was just a six-month placement, 87 00:05:05,640 --> 00:05:08,279 and his CV is impressive enough without it. 88 00:05:08,280 --> 00:05:11,440 So, why did he risk his career and lie about it? 89 00:05:14,153 --> 00:05:16,180 Has he lied about anything else? 90 00:05:16,473 --> 00:05:18,460 Everything else checks out. 91 00:05:18,993 --> 00:05:20,473 Are you sure about that? 92 00:05:23,913 --> 00:05:28,206 You have an injury over your left eye and a wound on your neck. 93 00:05:29,073 --> 00:05:31,520 How do you account for them, Simi? 94 00:05:32,273 --> 00:05:33,752 Yeah, I got mugged. 95 00:05:33,753 --> 00:05:36,193 - A kid with a knife. - Really? 96 00:05:37,492 --> 00:05:39,772 And did you report the assault? 97 00:05:40,233 --> 00:05:42,400 - No. - Why not? 98 00:05:42,793 --> 00:05:44,700 What, are you going to catch him? 99 00:05:46,553 --> 00:05:49,873 He's answered your questions, so unless you have other evidence? 100 00:06:13,113 --> 00:06:16,735 Tox results from the syringe used in the attack on Wilfred. 101 00:06:16,760 --> 00:06:18,520 - Here we go. - Let's have a look. 102 00:06:23,640 --> 00:06:26,000 - That's it? - Midazolam? 103 00:06:27,830 --> 00:06:30,030 That's a sedative, isn't it? 104 00:06:30,280 --> 00:06:31,320 Yeah. 105 00:06:33,128 --> 00:06:37,208 The full syringe would have had about five milligrams in it. 106 00:06:37,560 --> 00:06:38,860 That's not very much. 107 00:06:39,720 --> 00:06:43,799 So, either the assailant is incompetent, 108 00:06:43,800 --> 00:06:46,380 or this wasn't intended to kill him. 109 00:06:47,420 --> 00:06:49,180 So, what's the aim? 110 00:06:50,480 --> 00:06:51,820 Kidnapping? 111 00:06:56,780 --> 00:06:58,500 The guy's already ill. 112 00:06:59,080 --> 00:07:00,720 You know... 113 00:07:00,980 --> 00:07:04,900 If someone wanted him dead, it's not going to be that hard, is it? 114 00:07:05,360 --> 00:07:06,680 He's got leukaemia. 115 00:07:08,191 --> 00:07:11,500 It would look like natural causes if he died of sepsis. 116 00:07:13,699 --> 00:07:16,940 Should I get that syringe tested again for bacteria? 117 00:07:23,432 --> 00:07:25,959 What's this about Mr Okoye being moved? 118 00:07:25,960 --> 00:07:27,479 It's for his own safety. 119 00:07:27,480 --> 00:07:30,695 To the Cowley Institute? And who's paying for that? 120 00:07:30,720 --> 00:07:33,319 Oh, I've been assured that they have all the facilities required, 121 00:07:33,320 --> 00:07:35,580 and they've offered to do the treatment free of charge. 122 00:07:35,900 --> 00:07:37,399 I will not allow it. 123 00:07:37,400 --> 00:07:41,080 Someone in your hospital is trying to kill Mr Okoye. 124 00:07:41,873 --> 00:07:45,033 Quite frankly, Dr Braithwaite, I don't need your permission. 125 00:07:57,774 --> 00:07:59,300 Haematology lab. 126 00:08:00,500 --> 00:08:02,180 Dr Braithwaite here. 127 00:08:02,540 --> 00:08:07,439 Wilfred Okoye, hospital number 1187266. 128 00:08:07,440 --> 00:08:10,359 I want all his stored blood and marrow samples sent 129 00:08:10,360 --> 00:08:12,000 to my office immediately. 130 00:08:38,640 --> 00:08:39,900 Finished! 131 00:08:40,420 --> 00:08:45,940 79 needles swabbed and ready to go. 132 00:08:47,080 --> 00:08:48,820 You've got to see this. 133 00:08:49,440 --> 00:08:51,815 Microbiology results from the syringe 134 00:08:51,840 --> 00:08:53,760 used in the attack on Wilfred. 135 00:08:53,820 --> 00:08:57,060 Turns out it is full of bacteria - E coli. 136 00:08:58,820 --> 00:09:01,095 Well, it was lying around on the floor. 137 00:09:01,120 --> 00:09:02,159 Could it be a contaminant? 138 00:09:02,160 --> 00:09:04,919 No. It's a pure growth - just one type of bug in there. 139 00:09:04,920 --> 00:09:06,959 If it was a contaminant you'd expect to see 140 00:09:06,960 --> 00:09:08,479 lots of different organisms. 141 00:09:08,480 --> 00:09:10,360 It's been created deliberately. 142 00:09:11,108 --> 00:09:14,999 So, what? The killer sneaks into Wilfred's room pretending 143 00:09:15,000 --> 00:09:18,759 to be a nurse, inoculates him with the bacteria, 144 00:09:18,760 --> 00:09:20,580 but adds a mild sedative... 145 00:09:22,028 --> 00:09:25,079 ..so that when the real nurse comes in with his medication, 146 00:09:25,080 --> 00:09:28,940 he's asleep and can't tell her that someone else has already been in. 147 00:09:29,780 --> 00:09:31,839 He gets sepsis, he dies. 148 00:09:31,840 --> 00:09:33,380 Looks like natural causes. 149 00:09:34,660 --> 00:09:36,359 I need to tell DI Cracknell. 150 00:09:36,360 --> 00:09:39,200 You need to tell the doctors looking after Wilfred. 151 00:10:32,158 --> 00:10:35,399 It's as we expected - extensive peripheral oedema, 152 00:10:35,400 --> 00:10:38,439 multiple organ failure, consistent with sepsis. 153 00:10:38,440 --> 00:10:42,719 Yep. Toxicology shows only medications used for his treatment, 154 00:10:42,720 --> 00:10:46,199 antibiotics, ceftriaxone, gentamicin present 155 00:10:46,200 --> 00:10:47,919 in therapeutic concentrations. 156 00:10:47,920 --> 00:10:51,279 So, cause of death is consistent with deliberate inoculation 157 00:10:51,280 --> 00:10:54,159 of the culture of E coli, on a background 158 00:10:54,160 --> 00:10:57,359 of chemotherapy-induced immune compromise. 159 00:10:57,360 --> 00:11:00,479 Well, we've got no other leads on his attacker at present. 160 00:11:00,480 --> 00:11:02,879 We're liaising with the Beninese Consulate to inform 161 00:11:02,880 --> 00:11:04,740 the family of the deceased. 162 00:11:05,480 --> 00:11:10,500 DNA says Wilfred Okoye was guilty of Rahul's murder, 163 00:11:10,840 --> 00:11:13,489 but being unconscious, had the perfect alibi. 164 00:11:14,880 --> 00:11:17,879 When a murder suspect gets murdered, what does that mean? 165 00:11:17,880 --> 00:11:19,599 Framed by the real murderer? 166 00:11:19,600 --> 00:11:22,200 Why would you frame someone with the perfect alibi? 167 00:11:28,134 --> 00:11:29,860 Simi Jacobs. 168 00:11:30,420 --> 00:11:31,940 What's his home address? 169 00:11:32,280 --> 00:11:33,320 Erm... 170 00:11:34,997 --> 00:11:38,670 Let's see. Flat 32, Bardwell House, Lincoln Street. 171 00:11:38,920 --> 00:11:42,559 Thought so. Okoye and Jacobs have been living together. 172 00:11:42,560 --> 00:11:45,759 Simi Jacobs has already been released, guv. 173 00:11:45,760 --> 00:11:48,359 - What? - Yeah. Lack of forensics. 174 00:11:48,360 --> 00:11:49,559 All right. 175 00:11:49,560 --> 00:11:51,840 Might I suggest we pick him up again? 176 00:11:58,765 --> 00:12:00,845 It still doesn't get us anywhere. 177 00:12:00,931 --> 00:12:02,691 It doesn't explain the DNA. 178 00:12:02,716 --> 00:12:05,375 And Simi was in custody when Wilfred was attacked, 179 00:12:05,400 --> 00:12:06,799 so it doesn't even explain that. 180 00:12:06,800 --> 00:12:09,280 - We're just going round in circles. - Yep. 181 00:12:19,758 --> 00:12:23,319 When he was interviewed, Wilfred said his leukaemia 182 00:12:23,320 --> 00:12:26,240 was common in his region. 183 00:12:28,300 --> 00:12:30,000 Doesn't sound right to me. 184 00:12:46,840 --> 00:12:48,879 You have reached Dr Adam Yuen. 185 00:12:48,880 --> 00:12:50,319 I am unable to take your call. 186 00:12:50,320 --> 00:12:52,280 Please leave a message after the tone. 187 00:12:55,200 --> 00:12:57,159 Wait there. He's not in, guv. 188 00:12:57,160 --> 00:12:58,439 And the neighbours haven't seen him. 189 00:12:58,440 --> 00:13:00,880 He's not been seen back at work at the hospital either. 190 00:13:01,026 --> 00:13:03,640 You two stick around in case he comes back. 191 00:13:03,700 --> 00:13:07,260 I'm sorry, guv. I should have spotted the address. 192 00:13:08,820 --> 00:13:10,300 Don't worry about it. 193 00:13:10,780 --> 00:13:13,820 At least you didn't wrongly arrest a bereaved cancer patient. 194 00:13:18,223 --> 00:13:19,743 I'll do that next time. 195 00:13:23,906 --> 00:13:24,946 Bye. 196 00:13:30,000 --> 00:13:32,240 Nine missed calls. You're very persistent. 197 00:13:35,240 --> 00:13:37,060 I didn't want to end it like that. 198 00:13:39,520 --> 00:13:40,820 Can I help? 199 00:13:52,200 --> 00:13:55,239 You should have told me that Emily Braithwaite is your godmother. 200 00:13:55,240 --> 00:13:56,900 Some godmother. 201 00:13:57,160 --> 00:13:59,759 No doubt you've received the incriminating evidence about me. 202 00:13:59,760 --> 00:14:00,960 What evidence? 203 00:14:02,600 --> 00:14:05,695 She never sent it. I should have guessed. 204 00:14:05,720 --> 00:14:08,879 If she tried to blackmail you, then we'll make her answer for that. 205 00:14:08,880 --> 00:14:10,260 She's far too clever. 206 00:14:11,960 --> 00:14:14,620 Why do I think there's more to this than you're telling me? 207 00:14:16,248 --> 00:14:18,487 No, I just lied to advance my career. 208 00:14:18,488 --> 00:14:21,780 Really? Just to say you had a fellowship. Why would you do that? 209 00:14:27,063 --> 00:14:28,583 My family are all doctors. 210 00:14:28,608 --> 00:14:30,607 I was always going to be a surgeon. 211 00:14:30,608 --> 00:14:32,620 It was more or less decided for me. 212 00:14:34,208 --> 00:14:37,327 Final year of medical school, I was walking to uni 213 00:14:37,328 --> 00:14:40,567 and a cyclist is knocked off her bike, right in front of me. 214 00:14:40,568 --> 00:14:42,407 Now, I was a keen student. 215 00:14:42,408 --> 00:14:45,020 I used to carry a first aid kit around with me. 216 00:14:45,488 --> 00:14:48,780 If I'm honest, I was always waiting for something like this. 217 00:14:49,168 --> 00:14:52,100 When I think about that it's actually what I'm most ashamed of. 218 00:14:52,568 --> 00:14:54,500 She had facial injuries. 219 00:14:54,848 --> 00:14:57,695 Heavy, laboured breathing. She was losing consciousness fast. 220 00:14:57,720 --> 00:14:59,420 So, I thought, "She's suffocating. 221 00:14:59,640 --> 00:15:03,580 "She needs a surgical airway, a cricothyroidotomy." 222 00:15:04,000 --> 00:15:05,359 So, I made my incision. 223 00:15:05,360 --> 00:15:07,620 Something that I had practised on mannequins. 224 00:15:07,880 --> 00:15:11,540 What I didn't know is that she had an abnormal anatomy - 225 00:15:12,040 --> 00:15:15,700 an aberrant subclavian artery, looping high in the neck. 226 00:15:16,640 --> 00:15:19,959 It's present in 1% of people and 0% of mannequins. 227 00:15:19,960 --> 00:15:22,540 - How could you have known? - It was a bloodbath. 228 00:15:29,868 --> 00:15:32,708 The artery retracted back into her chest. 229 00:15:32,825 --> 00:15:35,080 There was nothing we could do to save her. 230 00:15:35,480 --> 00:15:37,900 She bled to death in minutes. 231 00:15:41,860 --> 00:15:44,820 My father was furious. 232 00:15:46,100 --> 00:15:48,719 Not because I stupidly tried a tracheostomy 233 00:15:48,720 --> 00:15:50,720 and killed an innocent young girl. 234 00:15:52,320 --> 00:15:56,220 But because I didn't study hard enough to do it competently. 235 00:15:58,100 --> 00:16:02,519 So, he used his influence and arranged for my fellowship 236 00:16:02,520 --> 00:16:04,780 - as cover. - For what? 237 00:16:08,520 --> 00:16:10,000 For my absence. 238 00:16:13,320 --> 00:16:16,600 It took months of therapy before I could even leave the house. 239 00:16:25,360 --> 00:16:28,959 The irony in all of this is that the one who helped me out 240 00:16:28,960 --> 00:16:30,640 the most was Emily Braithwaite. 241 00:16:31,798 --> 00:16:34,740 She visited me more often than my parents. 242 00:16:37,720 --> 00:16:38,960 She understood. 243 00:16:41,629 --> 00:16:43,949 But there was no way I was going to be a surgeon. 244 00:16:47,880 --> 00:16:50,020 So, I decided to choose pathology, 245 00:16:50,520 --> 00:16:54,400 and a false narrative was created as to why I made the switch. 246 00:16:56,080 --> 00:16:58,380 When you start lying, 247 00:16:59,000 --> 00:17:00,900 you have to keep lying. 248 00:17:20,853 --> 00:17:21,720 Jack. 249 00:17:21,744 --> 00:17:23,096 - Mm? - I need to talk to you. 250 00:17:23,120 --> 00:17:24,480 Sure, what's up...? 251 00:17:27,000 --> 00:17:27,900 Hi. 252 00:17:28,400 --> 00:17:29,520 Are you kidding me? 253 00:17:32,880 --> 00:17:35,239 He doesn't work here any more because he lied to us, do you 254 00:17:35,240 --> 00:17:37,707 - remember? Do you remember that? - Adam's got a theory about Wilfred. 255 00:17:37,708 --> 00:17:39,279 - Oh, right. - Just hear him out. 256 00:17:39,280 --> 00:17:43,519 So, um, I just have to trust him now? 257 00:17:43,520 --> 00:17:45,800 No, you've got to trust me. 258 00:17:49,253 --> 00:17:50,520 Think about it. 259 00:17:51,596 --> 00:17:54,360 Why would someone want Wilfred dead? 260 00:17:54,480 --> 00:17:56,759 What did he know that was such a threat that someone 261 00:17:56,760 --> 00:17:58,020 had to kill him? 262 00:17:59,220 --> 00:18:02,560 Wilfred was being treated for acute myeloid leukaemia. 263 00:18:02,880 --> 00:18:04,119 That's rare. 264 00:18:04,120 --> 00:18:06,639 Remember, he said there were lots of other cases in his small 265 00:18:06,640 --> 00:18:08,220 village in Africa. 266 00:18:08,840 --> 00:18:11,559 What if Wilfred wasn't killed because of what he knew? 267 00:18:11,560 --> 00:18:12,599 Don't follow. 268 00:18:12,600 --> 00:18:14,780 Wilfred wasn't the witness. 269 00:18:16,680 --> 00:18:18,140 He was the evidence. 270 00:18:21,260 --> 00:18:23,879 This is a trephine biopsy of the bone marrow. 271 00:18:23,880 --> 00:18:27,440 We take a thin core of bone with marrow cells in it. 272 00:18:27,600 --> 00:18:30,180 I've already taken an aspirate of the fluids. 273 00:18:41,020 --> 00:18:44,639 So, the question is, why would so many people from one place 274 00:18:44,640 --> 00:18:46,420 all get leukaemia? 275 00:18:47,280 --> 00:18:48,940 And that's going to tell you, is it? 276 00:18:49,120 --> 00:18:50,959 To be honest, I've never done this before. 277 00:18:50,960 --> 00:18:52,580 Not postmortem, anyway. 278 00:18:52,772 --> 00:18:55,137 But you know what? It's crazy enough for it to work. 279 00:18:55,440 --> 00:18:56,800 Mm-mm. 280 00:19:08,043 --> 00:19:09,083 Thanks. 281 00:19:10,832 --> 00:19:14,580 Oh, look. Here's a billion DNA results from the needles. 282 00:19:15,740 --> 00:19:17,940 Want to give me a hand going through these? 283 00:19:18,880 --> 00:19:20,040 Didn't think so. 284 00:19:37,844 --> 00:19:40,524 Nikki? The slide's ready when you want to have a look. 285 00:19:49,120 --> 00:19:51,759 Good yield of cells. More than I expected. 286 00:19:51,760 --> 00:19:54,199 Definitely acute myeloid leukaemia. 287 00:19:54,200 --> 00:19:57,360 It's not typical. Looks more like secondary AML. 288 00:19:57,680 --> 00:20:00,119 - Secondary to what? - A toxin of some sort. 289 00:20:00,120 --> 00:20:02,439 Some industrial chemical, for example, 290 00:20:02,440 --> 00:20:05,980 or chemotherapy for a different cancer. 291 00:20:06,440 --> 00:20:09,319 Right. And that can occur years after the original exposure. 292 00:20:09,320 --> 00:20:11,060 Decades, in some cases. 293 00:20:11,320 --> 00:20:15,020 So, there may be other victims, all exposed to the same thing? 294 00:20:16,920 --> 00:20:18,280 Makes sense. 295 00:20:36,933 --> 00:20:38,093 Can I help you? 296 00:20:38,118 --> 00:20:40,158 They told me Wilfred is here. 297 00:20:40,360 --> 00:20:41,860 Can I see him, yeah? 298 00:20:42,200 --> 00:20:44,660 - Er, you are? - Family. 299 00:20:46,680 --> 00:20:48,239 Do you want to take a seat? 300 00:20:48,240 --> 00:20:50,228 Will I be able to sit with him for a bit or...? 301 00:20:50,252 --> 00:20:51,520 I'll just check. 302 00:21:00,639 --> 00:21:02,959 I've found Rahul's murder weapon. 303 00:21:03,240 --> 00:21:06,999 One DNA profile matching Rahul, one matching Wilfred, 304 00:21:07,000 --> 00:21:08,759 just like we found at the scene. 305 00:21:08,760 --> 00:21:11,020 But there's a third profile. 306 00:21:12,520 --> 00:21:14,639 Yep. Simi Jacobs. 307 00:21:14,640 --> 00:21:16,679 Simi? He's here! 308 00:21:16,680 --> 00:21:19,600 What do you mean he's here? He wants to see Wilfred's body. 309 00:21:34,344 --> 00:21:37,144 This places Simi at the scene of Rahul's murder. 310 00:21:37,480 --> 00:21:39,300 We need to keep him here. 311 00:21:39,480 --> 00:21:41,080 Call DI Cracknell. 312 00:21:44,661 --> 00:21:45,799 So, hang on. 313 00:21:45,800 --> 00:21:47,157 Simi Jacobs just turned up at the lab. 314 00:21:47,181 --> 00:21:49,340 One needle injected into three people. 315 00:21:49,341 --> 00:21:50,780 Better get down here. 316 00:21:50,781 --> 00:21:53,135 Simi had a puncture wound to his neck. 317 00:21:53,160 --> 00:21:55,580 Rahul was stabbed in the chest, but Wilfred? 318 00:21:56,020 --> 00:21:57,919 And if Simi got in a fight with Rahul, 319 00:21:57,920 --> 00:21:59,639 why is Wilfred's blood spattered? 320 00:21:59,640 --> 00:22:02,559 Wilfred would have to have been in the room as well. 321 00:22:02,560 --> 00:22:04,560 Maybe he was. Genetically speaking. 322 00:22:05,880 --> 00:22:08,399 What if that needle only stabbed two people? 323 00:22:08,400 --> 00:22:10,283 Then one of them has two different types of DNA. 324 00:22:10,307 --> 00:22:11,256 Exactly. 325 00:22:11,280 --> 00:22:13,093 Huh? No, for that to work, it would 326 00:22:13,118 --> 00:22:15,079 mean Simi's walking around with Wilfred's blood inside him. 327 00:22:15,112 --> 00:22:17,056 - That's ridiculous. - Is it? 328 00:22:19,305 --> 00:22:22,599 - Bone marrow transplant. - And Wilfred was the donor. 329 00:22:22,600 --> 00:22:26,823 So, Simi's blood has Wilfred's DNA. 330 00:22:33,740 --> 00:22:35,460 Do you want to come this way? Yeah. 331 00:22:39,900 --> 00:22:40,980 Just there. 332 00:22:44,120 --> 00:22:46,879 Can I get you a tea? A glass of water or...? 333 00:22:46,880 --> 00:22:48,320 Oh, no, no! 334 00:22:48,760 --> 00:22:49,800 Thanks. 335 00:22:52,760 --> 00:22:55,080 You said that Wilfred was family? 336 00:22:55,160 --> 00:22:56,460 That's right. 337 00:22:57,411 --> 00:22:58,880 Was he a close relative? 338 00:23:00,200 --> 00:23:01,900 You ask a lot of questions. 339 00:23:02,520 --> 00:23:03,940 Remember me? 340 00:23:06,000 --> 00:23:07,780 I examined you at the station. 341 00:23:08,120 --> 00:23:09,439 I saw a scar on your chest. 342 00:23:09,440 --> 00:23:11,080 That's a Hickman line scar. 343 00:23:12,680 --> 00:23:14,700 Did you have a bone marrow transplant as a kid? 344 00:23:16,440 --> 00:23:18,239 Yeah, I'm going to go. 345 00:23:18,240 --> 00:23:21,320 Simi, we found your blood at the scene of Rahul's murder. 346 00:23:23,080 --> 00:23:24,320 Did you kill him? 347 00:23:27,160 --> 00:23:31,400 No, no, no. He... He came at me! He was insane! 348 00:23:31,840 --> 00:23:33,320 It was an accident! 349 00:23:37,240 --> 00:23:39,120 I just wanted to protect Wilfred. 350 00:23:41,120 --> 00:23:43,380 Wilfred saved my life when I was a kid. 351 00:23:43,920 --> 00:23:46,760 But you know what? He could only do that because he was a match. 352 00:23:46,960 --> 00:23:49,839 People have transplants from their brothers or mothers or whatever 353 00:23:49,840 --> 00:23:53,100 because they're a match. I had no-one. 354 00:23:54,160 --> 00:23:55,680 How did you find him? 355 00:23:55,704 --> 00:23:57,615 There's this charity attached to our church. 356 00:23:57,640 --> 00:23:59,640 They helped us get the transplant records. 357 00:24:01,178 --> 00:24:03,120 Only it turns out Wilfred was sick. 358 00:24:04,140 --> 00:24:06,080 - Were there others? - Yeah. 359 00:24:06,340 --> 00:24:09,520 I mean, loads of people in his village died from the same thing. 360 00:24:11,380 --> 00:24:13,020 We found Wilfred in time. 361 00:24:15,580 --> 00:24:17,020 So we thought. 362 00:24:18,940 --> 00:24:19,940 What? 363 00:24:21,100 --> 00:24:22,820 You're not going to let me see him? 364 00:24:26,900 --> 00:24:28,460 Simi. 365 00:24:29,620 --> 00:24:30,860 There he is. 366 00:24:51,380 --> 00:24:54,540 Ah, afternoon! Present from DI Cracknell - 367 00:24:54,820 --> 00:24:57,659 all the rubbish from Simi Jacobs' address. 368 00:24:57,660 --> 00:24:59,139 Thought you might want to take a look 369 00:24:59,140 --> 00:25:00,939 in case you find anything relevant. 370 00:25:00,940 --> 00:25:01,800 Joy. 371 00:25:01,824 --> 00:25:05,200 Can I introduce Reverend Kanu? You've already met Jack. 372 00:25:05,300 --> 00:25:07,200 This is Dr Nikki Alexander... 373 00:25:07,224 --> 00:25:08,921 - Hello. - And Dr Adam Yuen. 374 00:25:09,382 --> 00:25:12,739 Reverend Kanu runs the charitable organisation that was responsible 375 00:25:12,740 --> 00:25:14,619 for bringing Wilfred to the UK. 376 00:25:14,620 --> 00:25:16,419 I have some photos from our trip. 377 00:25:16,420 --> 00:25:19,120 Sergeant Galloway thinks they might help you. 378 00:25:19,144 --> 00:25:20,116 Thank you. 379 00:25:20,140 --> 00:25:22,920 I have to warn you, they're not pretty. 380 00:25:25,740 --> 00:25:27,980 Tell me how Mr Okoye came to be here. 381 00:25:29,555 --> 00:25:33,540 My church runs a charity that helps arrange treatment in the UK. 382 00:25:33,780 --> 00:25:36,820 They raise money, get doctors to volunteer, whatever. 383 00:25:38,060 --> 00:25:40,060 Wilfred's case was kind of special. 384 00:25:40,420 --> 00:25:43,900 I mean, he helped me years ago, and now he needed my help. 385 00:25:44,100 --> 00:25:46,280 The local newspaper picked up the story, 386 00:25:46,305 --> 00:25:47,800 it got a lot of publicity. 387 00:25:47,979 --> 00:25:49,796 So, the hospital agreed to treat him. 388 00:25:49,820 --> 00:25:52,520 - And he stayed at your flat? - Yeah. 389 00:25:54,540 --> 00:25:56,740 Nobody told me he don't speak English. 390 00:25:57,420 --> 00:25:59,220 I couldn't tell him anything. 391 00:26:00,260 --> 00:26:03,820 He didn't know who I was, what he did for me. 392 00:26:05,860 --> 00:26:08,660 Then I learnt that he's under the care of this Rahul guy. 393 00:26:10,500 --> 00:26:14,900 I have travelled widely in Africa as part of my ministry, 394 00:26:15,300 --> 00:26:20,700 and yet nothing could have prepared me for what we found in Bwendora. 395 00:26:23,060 --> 00:26:26,660 The town is remote, even by African standards. 396 00:26:27,820 --> 00:26:30,580 There is only very basic health care. 397 00:26:31,060 --> 00:26:33,860 It became clear there was a lot of sickness. 398 00:26:35,660 --> 00:26:38,820 This man died within hours of our arrival. 399 00:26:39,620 --> 00:26:44,059 The illness causes bleeding and rashes. Fever sometimes. 400 00:26:44,060 --> 00:26:46,219 What do the people think it's caused by? 401 00:26:46,220 --> 00:26:49,339 There's a large pesticide factory in the town. 402 00:26:49,340 --> 00:26:52,499 Many people think the water has been contaminated. 403 00:26:52,500 --> 00:26:55,459 They organised protests. 404 00:26:55,460 --> 00:26:58,419 People think there has been a cover-up. 405 00:26:58,420 --> 00:27:01,180 But the factory provides a lot of employment. 406 00:27:02,180 --> 00:27:05,620 It is a very divisive issue. 407 00:27:05,900 --> 00:27:10,300 The illness has ripped the heart out of the community. 408 00:27:10,620 --> 00:27:13,659 There are very few families it has left untouched. 409 00:27:13,660 --> 00:27:15,619 And they've had no outside help? 410 00:27:15,620 --> 00:27:18,860 There is one western charity which runs a clinic, 411 00:27:18,885 --> 00:27:20,765 but they only visit every few months. 412 00:27:23,568 --> 00:27:24,768 Some charity. 413 00:27:27,380 --> 00:27:28,700 Oh, Lord. 414 00:27:29,563 --> 00:27:31,787 Enlighten our minds with your truth. 415 00:27:33,780 --> 00:27:37,380 Give us the strength and the wisdom to seek justice. 416 00:27:38,620 --> 00:27:42,820 Shine your everlasting light into our darkness. 417 00:27:44,780 --> 00:27:47,940 There's a lot of talk about Rahul, all around the hospital. 418 00:27:48,180 --> 00:27:50,619 How the hospital is protecting him. 419 00:27:50,620 --> 00:27:53,660 How he messed up an operation and no-one wants to work with him. 420 00:27:54,060 --> 00:27:56,779 And you thought he shouldn't operate on Wilfred. 421 00:27:56,780 --> 00:28:00,779 The night before, I heard him arguing with this woman, 422 00:28:00,780 --> 00:28:02,899 Dr Braithwaite. 423 00:28:02,900 --> 00:28:04,979 She told Rahul not to do the operation 424 00:28:04,980 --> 00:28:07,300 and he just told her that she couldn't stop him. 425 00:28:07,780 --> 00:28:10,299 The bag of rubbish that we found at your home address. 426 00:28:10,300 --> 00:28:12,300 Was it from one of the offices? 427 00:28:12,463 --> 00:28:14,183 - Yeah. - Which one? 428 00:28:14,820 --> 00:28:16,219 All of them. 429 00:28:16,220 --> 00:28:18,659 I was looking for something, anything, 430 00:28:18,660 --> 00:28:20,499 I could use against Rahul. 431 00:28:20,500 --> 00:28:22,979 And on the morning of the operation? 432 00:28:22,980 --> 00:28:25,939 I saw Wilfred getting prepared for theatre and I panicked. 433 00:28:25,940 --> 00:28:27,699 I phoned Rahul. 434 00:28:27,700 --> 00:28:29,179 What did you say? 435 00:28:29,180 --> 00:28:31,539 I told him I had some information on him. 436 00:28:31,540 --> 00:28:35,659 I thought I could threaten to reveal what I knew if he did the operation. 437 00:28:35,660 --> 00:28:37,178 What information? 438 00:28:39,380 --> 00:28:42,889 I was bluffing. But I had to stop him. 439 00:28:45,660 --> 00:28:47,567 Well, you certainly managed that. 440 00:29:02,620 --> 00:29:04,099 How's it going? 441 00:29:04,100 --> 00:29:08,180 Oh, I'm in my element rummaging through the trash. You know me. 442 00:29:08,580 --> 00:29:10,939 Nothing much here, apart from a criminally lax attitude 443 00:29:10,940 --> 00:29:12,220 to recycling. 444 00:29:14,180 --> 00:29:16,179 Adam's still here, is he? 445 00:29:16,180 --> 00:29:18,179 We wouldn't have got this far without him. 446 00:29:18,180 --> 00:29:19,940 I want to trust him. 447 00:29:22,220 --> 00:29:23,340 What's that? 448 00:29:28,260 --> 00:29:29,548 Oh, my God. 449 00:29:30,780 --> 00:29:35,379 This was in that rubbish bag you found at Simi Jacobs' place. 450 00:29:35,380 --> 00:29:38,775 It's Harry Fletcher's ECG, taken the day of his operation. 451 00:29:38,800 --> 00:29:40,079 It's normal. 452 00:29:40,080 --> 00:29:43,679 And this is the ECG that appeared in Fletcher's notes. 453 00:29:43,680 --> 00:29:46,759 Same date and time, but grossly abnormal. 454 00:29:46,760 --> 00:29:50,559 We believe they were switched to deflect blame from Rahul 455 00:29:50,560 --> 00:29:52,620 after the operation went wrong. 456 00:29:52,920 --> 00:29:54,660 So, there was a cover-up? 457 00:29:54,880 --> 00:29:57,599 Well, what's this got to do with the murder investigation? 458 00:29:57,600 --> 00:30:00,559 Yeah, Simi Jacobs admitted to the attack on Arnie Rahul. 459 00:30:00,560 --> 00:30:03,439 I mean, he claims it was an accident as a result of self-defence. 460 00:30:03,440 --> 00:30:05,159 That fits with the crime scene findings. 461 00:30:05,160 --> 00:30:07,519 So, how does this transplant fit in? 462 00:30:07,520 --> 00:30:10,279 Well, Simi was born with sickle cell disease, 463 00:30:10,280 --> 00:30:14,439 and was treated with a bone marrow transplant at St Jude's as a child. 464 00:30:14,440 --> 00:30:17,239 Wilfred donated his stem cells for Simi's transplant. 465 00:30:17,240 --> 00:30:19,855 20 years later, Wilfred gets leukaemia. 466 00:30:19,880 --> 00:30:21,759 We don't think this is a coincidence. 467 00:30:21,760 --> 00:30:24,999 He had a type of leukaemia that can be caused by over-exposure 468 00:30:25,000 --> 00:30:26,039 to certain drugs. 469 00:30:26,040 --> 00:30:28,719 There's a technique known as mobilisation, 470 00:30:28,720 --> 00:30:32,080 which is designed to increase production of stem cells. 471 00:30:32,157 --> 00:30:36,759 Normally, stem cell donation involves giving a perfectly safe 472 00:30:36,760 --> 00:30:38,279 bone marrow stimulant. 473 00:30:38,280 --> 00:30:43,199 But whoever did this also gave Wilfred high levels of chemotherapy, 474 00:30:43,200 --> 00:30:44,839 and did so repeatedly. 475 00:30:44,840 --> 00:30:47,399 They gave chemo? To a volunteer? 476 00:30:47,400 --> 00:30:49,319 To yield even more stem cells. 477 00:30:49,320 --> 00:30:51,559 What for? More transplants? 478 00:30:51,560 --> 00:30:56,159 Stem cells have the ability to develop into any type of body cell. 479 00:30:56,160 --> 00:30:58,375 Brain, heart, blood - you name it. 480 00:30:58,400 --> 00:31:00,719 So there's a huge range of potential therapies 481 00:31:00,720 --> 00:31:04,279 in which they can be used, one of which is transplantation. 482 00:31:04,280 --> 00:31:09,332 About ten years ago, Braithwaite and her team identified stem cells 483 00:31:09,357 --> 00:31:11,159 that were very special indeed, 484 00:31:11,160 --> 00:31:14,719 capable of being turned into what are called killer T-cells, 485 00:31:14,720 --> 00:31:18,799 part of the immune system, which can be made to attack malignant tumours. 486 00:31:18,800 --> 00:31:21,159 The potential for this discovery was enormous. 487 00:31:21,160 --> 00:31:23,479 These magic cells all had the same gene, 488 00:31:23,480 --> 00:31:27,400 a gene we think might be common in Wilfred's town. 489 00:31:27,800 --> 00:31:31,599 They went looking for transplant donors to treat people like Simi, 490 00:31:31,600 --> 00:31:34,399 but what they discovered was something much bigger, 491 00:31:34,400 --> 00:31:36,519 so they went back for more, and more. 492 00:31:36,520 --> 00:31:39,159 Basically they were flogging him for every last stem cell 493 00:31:39,160 --> 00:31:41,559 - he could produce. - Him and all the others. 494 00:31:41,560 --> 00:31:43,879 Wilfred's town was basically a stem cell farm. 495 00:31:43,880 --> 00:31:47,319 Can you prove Wilfred was given the stimulating drugs? 496 00:31:47,320 --> 00:31:50,780 It may be possible, but that's way out of my league. 497 00:31:52,240 --> 00:31:54,120 Sounds like we need a second opinion. 498 00:32:14,120 --> 00:32:15,239 Thank you, Professor. 499 00:32:15,240 --> 00:32:17,079 Not at all. It's very good to see you. 500 00:32:17,080 --> 00:32:18,600 - Thank you. - Oh, he's away! 501 00:32:20,447 --> 00:32:23,999 - Adam, hello again. - Hello. This is Dr Nikki Alexander. 502 00:32:24,000 --> 00:32:25,280 - Hello. - How do you do? 503 00:32:25,304 --> 00:32:26,616 And you've already met DI Cracknell. 504 00:32:26,640 --> 00:32:28,240 Yes, of course. This way. 505 00:32:29,004 --> 00:32:30,684 That was Alfie. 506 00:32:30,880 --> 00:32:34,399 He's one of our early trial patients osteosarcoma. 507 00:32:34,400 --> 00:32:37,119 When he was referred to us, he was in a hospice 508 00:32:37,120 --> 00:32:40,420 on palliative treatment, expected to die within weeks. 509 00:32:40,469 --> 00:32:42,869 Please. That was two years ago. 510 00:32:43,988 --> 00:32:45,580 He's now disease-free. 511 00:32:48,100 --> 00:32:51,759 We wanted to show you some bone marrow samples from Mr Okoye. 512 00:32:51,760 --> 00:32:54,320 He was moved from St Jude's to be treated here. 513 00:33:02,367 --> 00:33:03,860 Hmm. 514 00:33:04,327 --> 00:33:05,967 Secondary leukaemia. 515 00:33:08,847 --> 00:33:10,326 They look very unusual. 516 00:33:10,327 --> 00:33:12,740 Mr Okoye was a stem cell donor. 517 00:33:13,167 --> 00:33:14,580 Was he? 518 00:33:14,887 --> 00:33:17,700 We were wondering if it might be stimulated. 519 00:33:18,127 --> 00:33:19,900 You mean Cyclo-G? 520 00:33:20,807 --> 00:33:22,020 Oh, dear. 521 00:33:22,287 --> 00:33:25,500 Yes, it's possible. 522 00:33:25,847 --> 00:33:28,140 Is there any way we can confirm it? 523 00:33:28,767 --> 00:33:31,646 You would need to look into the genetics of his blood cells. 524 00:33:31,647 --> 00:33:33,766 There are some telltale signs. 525 00:33:33,767 --> 00:33:37,126 We have several world experts in cytogenetics here. 526 00:33:37,127 --> 00:33:38,960 They'd be happy to help. 527 00:33:39,367 --> 00:33:42,535 Your cancer therapies are based on Braithwaite's stem cell research, 528 00:33:42,560 --> 00:33:46,679 - are they not? - Yes. Yes. I've never denied it. 529 00:33:46,680 --> 00:33:49,360 Hers was an extraordinary piece of work. 530 00:33:50,520 --> 00:33:53,599 She tried for years to turn it into a practical treatment, 531 00:33:53,600 --> 00:33:58,199 but, in the end, she was stumped by the obvious problem. 532 00:33:58,200 --> 00:34:00,079 The limited supply of donors. 533 00:34:00,080 --> 00:34:01,280 Precisely. 534 00:34:01,360 --> 00:34:05,940 So, what we brought to the party is called gene editing. 535 00:34:07,000 --> 00:34:09,919 We found a way of inserting the special gene 536 00:34:09,920 --> 00:34:13,320 into any old stem cell, and the result is... 537 00:34:13,820 --> 00:34:15,600 Well, you met Alfie. 538 00:34:16,680 --> 00:34:19,300 What is your relationship to Emily Braithwaite? 539 00:34:20,620 --> 00:34:21,900 Yes. 540 00:34:22,280 --> 00:34:25,140 Well, I suppose you'd say we're rivals. 541 00:34:25,440 --> 00:34:28,780 She's never forgiven me for succeeding where she failed. 542 00:34:29,320 --> 00:34:33,319 But I'm afraid her star has been waning for some time. 543 00:34:33,320 --> 00:34:34,760 What makes you say that? 544 00:34:36,883 --> 00:34:38,883 She came to ask for my help. 545 00:34:38,908 --> 00:34:42,319 Believe me, that alone suggests desperation. 546 00:34:42,320 --> 00:34:46,200 She had just lost a very large research grant. 547 00:34:46,480 --> 00:34:49,039 Is it possible that Braithwaite poisoned Mr Okoye 548 00:34:49,040 --> 00:34:52,000 and everyone else in his town to get more stem cells? 549 00:34:52,400 --> 00:34:54,620 That's a serious accusation. 550 00:34:54,980 --> 00:34:56,700 Everything's falling apart. 551 00:34:56,960 --> 00:34:59,359 So, like a gambler, she risks more and more, 552 00:34:59,360 --> 00:35:02,040 desperate for that big win to get herself back on top. 553 00:35:57,356 --> 00:35:59,160 - Now what? - Excuse me? 554 00:35:59,826 --> 00:36:03,066 - You do realise my career is over? - And that's my fault? 555 00:36:03,393 --> 00:36:05,199 There's got to be a way out of this. 556 00:36:05,200 --> 00:36:06,720 You owe me that at least. 557 00:36:07,812 --> 00:36:10,452 You want Auntie Emily to make it better? 558 00:36:11,949 --> 00:36:15,340 All those years I stuck up for you with your father. 559 00:36:16,020 --> 00:36:18,500 You messed up. Again. 560 00:36:18,980 --> 00:36:21,040 For once in your life, own it. 561 00:36:23,160 --> 00:36:24,460 I don't get it. 562 00:36:24,760 --> 00:36:26,279 You and Rahul. 563 00:36:26,280 --> 00:36:28,479 You go to all these lengths to protect his reputation, 564 00:36:28,480 --> 00:36:31,239 yet you show no interest in who might have killed him. 565 00:36:31,240 --> 00:36:33,600 You don't even seem to even care that he's dead! 566 00:36:35,000 --> 00:36:37,560 Maybe I've learnt to bury my emotions. 567 00:36:39,548 --> 00:36:40,748 You should try it. 568 00:36:42,520 --> 00:36:44,240 You know they're onto you, 569 00:36:44,600 --> 00:36:46,500 and I'm not going to help you this time. 570 00:36:46,718 --> 00:36:48,260 Oh, please. 571 00:36:50,200 --> 00:36:51,640 This is so painful. 572 00:36:58,400 --> 00:37:00,839 So, all roads lead to Braithwaite. 573 00:37:00,840 --> 00:37:02,940 Yes, but it's all circumstantial. 574 00:37:03,160 --> 00:37:05,839 There's nothing directly connecting her to Wilfred. 575 00:37:05,840 --> 00:37:08,322 If you can find me something concrete, I'll bring her in, 576 00:37:08,347 --> 00:37:10,119 but until then, it's just speculation. 577 00:37:10,120 --> 00:37:11,980 Adam, where did you get to? 578 00:37:12,520 --> 00:37:15,455 Rahul's conduct during Fletcher's operation amounted to 579 00:37:15,480 --> 00:37:17,039 criminal negligence. 580 00:37:17,040 --> 00:37:19,119 He could have been charged for manslaughter. 581 00:37:19,120 --> 00:37:20,519 Well, he's dead. 582 00:37:20,520 --> 00:37:22,399 What if Braithwaite covered it up? 583 00:37:22,400 --> 00:37:25,039 That's attempting to pervert the course of justice. 584 00:37:25,040 --> 00:37:26,439 Which means you can arrest her. 585 00:37:26,440 --> 00:37:29,839 Oh, and how do we know that Braithwaite swaps the ECG? 586 00:37:29,840 --> 00:37:32,239 We can't. There are several sets of prints on the trace, 587 00:37:32,240 --> 00:37:33,639 one of which could be Braithwaite's. 588 00:37:33,640 --> 00:37:35,999 Exactly, so we can't just arrest her on the off-chance that 589 00:37:36,000 --> 00:37:37,399 - her prints are on there. - I know. 590 00:37:37,400 --> 00:37:39,200 I met her for a drink. 591 00:37:42,460 --> 00:37:44,220 Her prints are on this glass. 592 00:37:44,245 --> 00:37:47,961 When you find that they are the same as the sets on the ECG, 593 00:37:48,062 --> 00:37:50,535 - then you can arrest her. - That's not admissible as evidence! 594 00:37:50,560 --> 00:37:52,200 It doesn't have to be. 595 00:37:53,383 --> 00:37:56,680 How do we know for sure she touched this glass? 596 00:37:57,120 --> 00:37:59,320 Well, you're just going to have to trust me. 597 00:38:45,960 --> 00:38:47,440 You two go round the back. 598 00:38:59,080 --> 00:39:01,300 Her car's here. Looks like she's home. 599 00:39:04,240 --> 00:39:05,280 No letterbox. 600 00:39:09,760 --> 00:39:11,120 Dr Braithwaite? 601 00:39:12,120 --> 00:39:14,620 DS Galloway. Could you open the door, please? 602 00:39:18,840 --> 00:39:21,300 - Police! - Dr Braithwaite? 603 00:39:33,080 --> 00:39:34,160 Shit. 604 00:39:40,440 --> 00:39:42,540 No sign of external injury. 605 00:39:43,920 --> 00:39:47,319 Both front and back doors were locked from the inside. 606 00:39:47,320 --> 00:39:49,580 There's no signs of forced entry. 607 00:39:49,920 --> 00:39:51,780 Everything's neat and tidy. 608 00:39:53,600 --> 00:39:55,260 Sudden chest pain, maybe? 609 00:39:56,480 --> 00:39:57,820 Or suicide. 610 00:40:29,960 --> 00:40:33,060 Nikki. Adam. Look at these. 611 00:40:38,360 --> 00:40:41,820 Two samples with Wilfred Okoye's name on. 612 00:41:04,560 --> 00:41:05,980 Look at this. 613 00:41:06,520 --> 00:41:08,220 The boiler's locked out. 614 00:41:08,800 --> 00:41:10,460 Yeah. Mine does that all the time. 615 00:41:10,720 --> 00:41:12,100 Bloody things. 616 00:41:50,360 --> 00:41:52,920 Heart weighs 380g. 617 00:42:19,080 --> 00:42:21,980 Evidence of left ventricular hypertrophy. 618 00:42:23,280 --> 00:42:24,940 Valves unremarkable. 619 00:42:28,080 --> 00:42:31,680 Left anterior descending coronary artery. 620 00:42:31,920 --> 00:42:35,340 Moderate stenosis, no evidence of thrombus. 621 00:42:42,995 --> 00:42:45,839 The toxicology was entirely negative, 622 00:42:45,840 --> 00:42:48,300 apart from a modest level of alcohol. 623 00:42:48,560 --> 00:42:52,180 No paracetamol, no benzodiazepines, nothing. 624 00:42:52,520 --> 00:42:56,119 So this, together with the absence of pills and containers 625 00:42:56,120 --> 00:42:59,079 at the address, and the absence of any needle marks on the body, 626 00:42:59,080 --> 00:43:02,239 leads me to conclude that death was not as a result 627 00:43:02,240 --> 00:43:04,540 of suicide or poisoning. 628 00:43:04,800 --> 00:43:08,279 In fact, the only significant finding from the postmortem 629 00:43:08,280 --> 00:43:11,239 examination is moderate ischaemic heart disease, 630 00:43:11,240 --> 00:43:14,679 together with hypertrophy of the septum and left ventricular wall. 631 00:43:14,680 --> 00:43:17,639 But no evidence of coronary thrombosis? 632 00:43:17,640 --> 00:43:19,280 The ventricular wall thickness... 633 00:43:19,304 --> 00:43:20,895 - Heart attack. - ..and the degree 634 00:43:20,920 --> 00:43:24,479 of myocardial disarray on microscopy are borderline 635 00:43:24,480 --> 00:43:26,399 for a diagnosis of HCM. 636 00:43:26,400 --> 00:43:29,359 - What's that? - Hypertrophic cardiomyopathy. 637 00:43:29,360 --> 00:43:32,639 It's an inherited heart condition that can lead to sudden death. 638 00:43:32,640 --> 00:43:34,920 - Fabrice Muamba. - Yes. 639 00:43:36,448 --> 00:43:40,399 Bolton Wanderers versus Tottenham. FA Cup quarterfinal, 2012. 640 00:43:40,400 --> 00:43:42,319 He collapsed on the pitch. Nearly died. 641 00:43:42,320 --> 00:43:44,159 Well, technically he did. 642 00:43:44,160 --> 00:43:46,439 In cases of high stress or exercise, 643 00:43:46,440 --> 00:43:50,359 the heart can lead into an abnormal rhythm, which can be fatal. 644 00:43:50,360 --> 00:43:53,279 And Emily Braithwaite was under a lot of stress. 645 00:43:53,280 --> 00:43:57,199 So it is possible that this caused a dysrhythmic event... 646 00:43:57,200 --> 00:43:58,647 - Heart attack. - Heart attack. 647 00:43:58,672 --> 00:44:00,360 ..that led to her death, don't you think? 648 00:44:04,441 --> 00:44:06,440 How come she didn't have a letterbox? 649 00:44:06,441 --> 00:44:08,800 It's a passive house. It's so well-insulated, 650 00:44:08,801 --> 00:44:11,480 it doesn't need heating. You heat it up just by living in it. 651 00:44:11,481 --> 00:44:13,240 But it has to be really airtight. 652 00:44:13,241 --> 00:44:15,360 It's like living in a bubble. 653 00:44:15,361 --> 00:44:18,561 All the air goes in and out through a single ventilation system. 654 00:44:20,201 --> 00:44:22,100 But why would the boiler lock out? 655 00:44:22,940 --> 00:44:27,560 What if it was faulty and produced a lot of carbon monoxide? 656 00:44:27,561 --> 00:44:30,220 No carbon monoxide in the toxicology. 657 00:44:34,201 --> 00:44:36,800 She's a suspect in a murder case. She conveniently dies. 658 00:44:36,801 --> 00:44:38,640 What if others were involved? 659 00:44:38,641 --> 00:44:40,760 If you can tell me how they did it, I'll believe you, 660 00:44:40,761 --> 00:44:43,880 but until then, it's looking like natural causes. 661 00:44:44,281 --> 00:44:47,840 Right, then, provisional assumption is that Braithwaite 662 00:44:47,841 --> 00:44:50,560 was guilty of conspiracy to murder Wilfred Okoye, 663 00:44:50,561 --> 00:44:53,520 as well as perverting the course of justice in the Fletcher case. 664 00:44:53,521 --> 00:44:54,720 What about Simi? 665 00:44:54,721 --> 00:44:58,340 That's up to the CPS, whether they buy a self-defence plea. 666 00:44:58,761 --> 00:45:00,281 I'll keep you posted. 667 00:45:17,983 --> 00:45:20,263 So this is where you've been hiding. 668 00:45:22,761 --> 00:45:24,340 Adam told you, then? 669 00:45:24,561 --> 00:45:27,081 Oh, yeah. He told me everything. 670 00:46:23,481 --> 00:46:24,880 I don't get it. 671 00:46:24,881 --> 00:46:27,880 How could someone like Braithwaite justify it to herself, 672 00:46:27,881 --> 00:46:29,200 let alone anyone else? 673 00:46:29,201 --> 00:46:31,720 They get fixated on the prize, don't they? 674 00:46:31,721 --> 00:46:34,760 The breakthrough, and all the acclaim that goes with it. 675 00:46:34,784 --> 00:46:36,080 Mm. 676 00:46:36,401 --> 00:46:39,820 Did you ever want to do something like that? Fancy research job? 677 00:46:40,601 --> 00:46:42,441 I think you'd be really good at that. 678 00:46:45,361 --> 00:46:46,540 I don't know. 679 00:46:47,521 --> 00:46:49,820 - It's more Adam's world. - Mm. 680 00:46:50,561 --> 00:46:51,761 Not any more. 681 00:46:53,441 --> 00:46:55,980 You can see how liberated he's been. 682 00:46:56,201 --> 00:46:59,020 He's carried that secret around for so long. 683 00:46:59,281 --> 00:47:02,060 Well, he's stopped trying to be all things to all men. 684 00:47:02,841 --> 00:47:06,020 And I'll tell you, he loves beating himself up. 685 00:48:05,201 --> 00:48:08,720 Hi. I'm working on the case of Wilfred Okoye. 686 00:48:08,721 --> 00:48:11,135 I was wondering if I could get his microbiology results 687 00:48:11,160 --> 00:48:12,440 from his stay here. 688 00:48:12,600 --> 00:48:15,360 Date of birth is 9/7/66. 689 00:48:20,204 --> 00:48:22,804 I just need to, er, speak to my supervisor. 690 00:48:23,000 --> 00:48:24,240 OK. Thank you. 691 00:49:03,720 --> 00:49:05,100 It's Adam. 692 00:49:07,680 --> 00:49:09,340 "We were wrong about everything. 693 00:49:11,060 --> 00:49:14,140 - "At Cowley Institute. Come quickly." - What? 694 00:49:17,243 --> 00:49:18,960 What are we looking at? 695 00:49:19,280 --> 00:49:22,220 Wilfred's blood cultures. Microbiology report. 696 00:49:24,787 --> 00:49:26,027 Hang on. 697 00:49:27,202 --> 00:49:30,180 The antibiotic sensitivities have been reversed. 698 00:49:30,849 --> 00:49:32,329 Who's done that? Braithwaite? 699 00:49:32,524 --> 00:49:35,084 Couldn't be. These are from the Cowley institute. 700 00:49:37,701 --> 00:49:39,660 Adam needs us. Come on. 701 00:50:10,263 --> 00:50:13,103 Oh, great. We were supposed to go left back at the lights. 702 00:50:30,588 --> 00:50:31,708 Dr Yuen? 703 00:50:31,733 --> 00:50:34,020 You know Emily Braithwaite died yesterday? 704 00:50:35,080 --> 00:50:39,319 What? Uh, no. How did it happen? 705 00:50:39,320 --> 00:50:42,480 Unknown. Found dead in a house that was bolted from the inside. 706 00:50:44,000 --> 00:50:46,860 Oh, look, an oxygen analyser. 707 00:50:47,960 --> 00:50:49,639 Do you always keep one of those in your car? 708 00:50:49,640 --> 00:50:51,439 I use it for various things. 709 00:50:51,440 --> 00:50:54,719 So Emily died just as you convinced us she was guilty. 710 00:50:54,720 --> 00:50:57,440 Her work was based on exploitation. 711 00:50:57,680 --> 00:50:59,540 Well, she can't deny that now, can she? 712 00:50:59,695 --> 00:51:01,039 Well, whatever happened, 713 00:51:01,040 --> 00:51:04,039 I'm sure forensic science will find the answer. 714 00:51:04,101 --> 00:51:07,880 Mm. Then I realised just how much liquid nitrogen you go through here. 715 00:51:08,000 --> 00:51:10,000 Two deliveries in three days? 716 00:51:12,160 --> 00:51:14,900 I mean, that is some evil genius stuff. 717 00:51:15,260 --> 00:51:17,220 Pretty quick and very clean. 718 00:51:17,500 --> 00:51:20,900 Except the pilot light in the boiler went out at Braithwaite's house. 719 00:51:21,140 --> 00:51:22,860 Otherwise, the perfect crime. 720 00:51:23,740 --> 00:51:25,359 Are you insane? 721 00:51:25,360 --> 00:51:28,640 - Oh, sorry. That's forensic science. - Get out. 722 00:51:32,461 --> 00:51:35,180 Braithwaite had Wilfred's blood samples. She was onto you. 723 00:51:36,300 --> 00:51:38,439 My research is changing lives. 724 00:51:38,440 --> 00:51:40,159 She never made the crucial breakthrough, 725 00:51:40,160 --> 00:51:41,560 but then again, neither did you. 726 00:51:41,720 --> 00:51:43,879 You reckon you'll crack it any minute now, don't you? 727 00:51:43,880 --> 00:51:46,359 You just have to keep going, keep blasting innocent men 728 00:51:46,360 --> 00:51:48,519 and women with poisonous drugs, and then you'll get there. 729 00:51:48,520 --> 00:51:51,319 - You know nothing. - There's no gene editing going on here. 730 00:51:51,320 --> 00:51:54,039 Your magic treatments are all from stem cells that you get 731 00:51:54,040 --> 00:51:55,399 from killing people like Wilfred. 732 00:51:55,400 --> 00:51:58,999 When childhood cancer is a thing of the past thanks to me, 733 00:51:59,000 --> 00:52:00,540 no-one will care. 734 00:52:01,060 --> 00:52:03,140 That's what it's all about, isn't it? 735 00:52:04,040 --> 00:52:06,325 It's not about the money or the power. 736 00:52:07,246 --> 00:52:09,080 It's about the prestige. 737 00:52:09,972 --> 00:52:12,220 So what are you going to do about it, Adam? 738 00:52:12,540 --> 00:52:14,759 Mm? You're discredited. 739 00:52:14,760 --> 00:52:16,200 You're getting struck off. 740 00:52:17,415 --> 00:52:19,500 Of course I know! 741 00:52:19,900 --> 00:52:21,340 I know everything. 742 00:52:23,420 --> 00:52:25,860 You've no idea who you're dealing with. 743 00:52:28,260 --> 00:52:29,380 Adam? 744 00:52:31,860 --> 00:52:33,160 Adam! 745 00:52:38,880 --> 00:52:41,399 Adam? What's happening? 746 00:52:41,400 --> 00:52:44,260 Cowley's the one exploiting Wilfred and the rest of the donors. 747 00:52:44,740 --> 00:52:47,199 And he killed Braithwaite with liquid nitrogen. 748 00:52:47,200 --> 00:52:49,319 He poured it in the vent of her airtight house, 749 00:52:49,320 --> 00:52:52,359 turning it into a gas chamber. She suffocated. 750 00:52:52,360 --> 00:52:55,799 Cowley did a deal with Rahul to kill Wilfred during surgery. 751 00:52:55,800 --> 00:52:58,720 And when that failed, he attacked Wilfred with the bacteria... 752 00:53:00,567 --> 00:53:03,279 ..to make sure he switched the micro reports 753 00:53:03,280 --> 00:53:04,940 so that the antibiotics wouldn't work. 754 00:53:18,427 --> 00:53:19,627 Adam? 755 00:53:20,634 --> 00:53:21,954 Adam! 756 00:53:41,840 --> 00:53:45,440 - I'm sure that's Cowley. - Really? Call Cracknell. 757 00:53:45,480 --> 00:53:47,880 - But... - Get after him. I'll find Adam. 758 00:53:56,058 --> 00:54:00,058 Yeah, I'm heading north on Colbridge Road. 759 00:54:00,480 --> 00:54:02,720 It's a black Mercedes. 760 00:54:02,900 --> 00:54:04,080 Adam? 761 00:54:04,282 --> 00:54:05,402 Adam! 762 00:54:05,660 --> 00:54:07,020 Oh, Jesus. 763 00:54:10,380 --> 00:54:11,620 Ambulance. 764 00:54:18,020 --> 00:54:19,880 Can you hear me? Adam? 765 00:54:20,260 --> 00:54:22,140 You took your time, mate. 766 00:54:22,780 --> 00:54:24,420 Come to take all the credit? 767 00:54:26,020 --> 00:54:27,380 Oh, man. 768 00:54:28,380 --> 00:54:31,060 The ambulance is on its way. What happened? 769 00:54:31,500 --> 00:54:32,860 I messed up. 770 00:54:48,860 --> 00:54:50,180 You trusted me. 771 00:54:53,500 --> 00:54:54,940 That means a lot. 772 00:54:56,900 --> 00:54:59,379 Adam. Adam, stay with me. 773 00:54:59,380 --> 00:55:01,699 Adam. Come on, man. Stay with me. Stay with me. 774 00:55:01,700 --> 00:55:02,980 Come on! Adam! 775 00:55:04,260 --> 00:55:05,300 Adam! 776 00:55:52,200 --> 00:55:53,240 Oh, God. 777 00:56:00,234 --> 00:56:01,634 Oh, no. 60434

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