All language subtitles for Vitamania.720p.HDTV.x264.AAC.MVGroup.org.eng

af Afrikaans
ak Akan
sq Albanian
am Amharic
ar Arabic Download
hy Armenian
az Azerbaijani
eu Basque
be Belarusian
bem Bemba
bn Bengali
bh Bihari
bs Bosnian
br Breton
bg Bulgarian
km Cambodian
ca Catalan
ceb Cebuano
chr Cherokee
ny Chichewa
zh-CN Chinese (Simplified) Download
zh-TW Chinese (Traditional)
co Corsican
hr Croatian Download
cs Czech
da Danish
nl Dutch
en English Download
eo Esperanto
et Estonian Download
ee Ewe
fo Faroese
tl Filipino
fi Finnish
fr French Download
fy Frisian
gaa Ga
gl Galician
ka Georgian
de German Download
gn Guarani
gu Gujarati
ht Haitian Creole
ha Hausa
haw Hawaiian
iw Hebrew
hi Hindi
hmn Hmong
hu Hungarian Download
is Icelandic
ig Igbo
id Indonesian
ia Interlingua
ga Irish
it Italian Download
ja Japanese
jw Javanese
kn Kannada
kk Kazakh
rw Kinyarwanda
rn Kirundi
kg Kongo
ko Korean
kri Krio (Sierra Leone)
ku Kurdish
ckb Kurdish (Soranî)
ky Kyrgyz
lo Laothian
la Latin
lv Latvian
ln Lingala
lt Lithuanian
loz Lozi
lg Luganda
ach Luo
lb Luxembourgish
mk Macedonian
mg Malagasy
ms Malay
ml Malayalam
mt Maltese
mi Maori
mr Marathi
mfe Mauritian Creole
mo Moldavian
mn Mongolian
my Myanmar (Burmese)
sr-ME Montenegrin
ne Nepali
pcm Nigerian Pidgin
nso Northern Sotho
no Norwegian
nn Norwegian (Nynorsk)
oc Occitan
or Oriya
om Oromo
ps Pashto
fa Persian
pl Polish Download
pt-BR Portuguese (Brazil)
pt Portuguese (Portugal) Download
pa Punjabi
qu Quechua
ro Romanian Download
rm Romansh
nyn Runyakitara
ru Russian
sm Samoan
gd Scots Gaelic
sr Serbian
sh Serbo-Croatian
st Sesotho
tn Setswana
crs Seychellois Creole
sn Shona
sd Sindhi
si Sinhalese
sk Slovak
sl Slovenian
so Somali
es Spanish Download
es-419 Spanish (Latin American)
su Sundanese
sw Swahili
sv Swedish
tg Tajik
ta Tamil
tt Tatar
te Telugu
ti Tigrinya
to Tonga
lua Tshiluba
tum Tumbuka
tr Turkish Download
tk Turkmen
tw Twi
ug Uighur
uk Ukrainian
ur Urdu
uz Uzbek
vi Vietnamese
cy Welsh
wo Wolof
xh Xhosa
yi Yiddish
yo Yoruba
zu Zulu
Would you like to inspect the original subtitles? These are the user uploaded subtitles that are being translated: 1 00:00:00,973 --> 00:00:03,723 (peaceful music) 2 00:00:10,695 --> 00:00:14,455 (children shouting) 3 00:00:14,455 --> 00:00:18,386 At 12, Cian Moore loved playing football 4 00:00:18,386 --> 00:00:20,947 until his eyes started to hurt 5 00:00:20,947 --> 00:00:25,447 He had trouble focusing, reading, even kicking a ball. 6 00:00:26,666 --> 00:00:29,456 He withdrew from people 7 00:00:29,456 --> 00:00:31,803 Cian was going blind. 8 00:00:31,803 --> 00:00:36,308 I was terrified because I don't want to go blind. 9 00:00:36,308 --> 00:00:38,720 For three years, his mother took him 10 00:00:38,720 --> 00:00:42,446 to many doctors, trying to find out why. 11 00:00:42,446 --> 00:00:46,840 Those three years were the worst of being told 12 00:00:46,840 --> 00:00:50,793 "There's nothing we can do," so it's like okay, he's blind, 13 00:00:50,793 --> 00:00:52,430 he'll be blind. 14 00:00:55,690 --> 00:00:58,322 What no doctor thought to prescribe through all of those 15 00:00:58,322 --> 00:01:02,725 consultations was these, just two capsules a year 16 00:01:02,725 --> 00:01:04,887 can save a child's sight. 17 00:01:04,887 --> 00:01:06,983 It can even save their life. 18 00:01:06,983 --> 00:01:10,250 In fact, this remedy has already saved over five million 19 00:01:10,250 --> 00:01:14,192 lives, but this isn't a medicine, it isn't a drug. 20 00:01:15,249 --> 00:01:16,749 This is vitamin A. 21 00:01:19,862 --> 00:01:23,589 But why was Cian so low in this vitamin? 22 00:01:23,589 --> 00:01:26,280 Well, since he was six year olds, he lived on bland 23 00:01:26,280 --> 00:01:29,973 foods such as chicken and chips, he wouldn't touch any 24 00:01:29,973 --> 00:01:32,706 fresh fruit or vegetables. 25 00:01:32,706 --> 00:01:36,808 He'd starve, he wouldn't care or if you would make him 26 00:01:36,808 --> 00:01:38,308 he would vomit it. 27 00:01:39,811 --> 00:01:42,557 Hundreds of thousands of malnourished children 28 00:01:42,557 --> 00:01:46,635 are on the brink of going blind because they lack vitamin A. 29 00:01:46,635 --> 00:01:50,106 Most are in developing countries, and caught early, 30 00:01:50,106 --> 00:01:52,439 their sight can be restored. 31 00:01:53,921 --> 00:01:57,381 For Cian, high dose vitamin A supplements saved the sight 32 00:01:57,381 --> 00:02:02,214 in his right eye, but he's permanently blind in the other. 33 00:02:03,246 --> 00:02:07,320 Vitamin A literally has the power to make the blind see, 34 00:02:07,320 --> 00:02:08,503 yet here's the rub. 35 00:02:08,503 --> 00:02:11,565 Taking extra vitamin A will not offer any benefit if you 36 00:02:11,565 --> 00:02:15,871 already have enough, and too much is toxic. 37 00:02:15,871 --> 00:02:17,204 It can kill you. 38 00:02:21,952 --> 00:02:25,941 In 1913, Antarctic explorers Douglas Mawson and Xavier 39 00:02:25,941 --> 00:02:29,695 Mertz were fighting for their lives. 40 00:02:29,695 --> 00:02:33,814 With most of their food gone, they faced a stark choice. 41 00:02:33,814 --> 00:02:35,647 Eat their dogs or die. 42 00:02:43,303 --> 00:02:48,130 After reluctantly eating their dogs, the men fell ill, 43 00:02:48,130 --> 00:02:49,596 burning with fever. 44 00:02:50,935 --> 00:02:53,856 Within days, Mertz was dead. 45 00:02:53,856 --> 00:02:57,773 Mawson, against the odds, made it back to camp. 46 00:02:59,737 --> 00:03:00,570 Ho! 47 00:03:02,380 --> 00:03:05,313 (dogs whining) 48 00:03:05,313 --> 00:03:07,704 So what was the mystery illness that 49 00:03:07,704 --> 00:03:11,605 killed Mertz and nearly cost Mawson his life? 50 00:03:11,605 --> 00:03:13,907 Well, when they ate their dogs, they weren't just eating 51 00:03:13,907 --> 00:03:18,907 canine flesh and fat, they also ate the dog's livers which 52 00:03:19,115 --> 00:03:21,865 contain high levels of vitamin A. 53 00:03:25,366 --> 00:03:28,400 So basically, they overdosed. 54 00:03:28,400 --> 00:03:32,873 Mertz went mad, his condition known as hypervitaminosis A. 55 00:03:34,765 --> 00:03:39,765 Hypervitaminosis A is rare, but deadly, and today, we know 56 00:03:40,970 --> 00:03:43,227 it can be caused by overuse of high dose vitamin A 57 00:03:43,227 --> 00:03:46,786 supplements, the same kind of supplements that can save 58 00:03:46,786 --> 00:03:48,119 a child's sight. 59 00:03:53,975 --> 00:03:58,975 This power and complexity lies at the heart of the great 60 00:03:59,215 --> 00:04:01,101 vitamin story. 61 00:04:01,101 --> 00:04:03,851 (dramatic music) 62 00:04:08,150 --> 00:04:11,684 I'm embarking on an epic, world spanning investigation 63 00:04:11,684 --> 00:04:14,184 of vitamin science in history. 64 00:04:15,976 --> 00:04:17,726 That is one big fish. 65 00:04:18,734 --> 00:04:21,680 I want to know how we discovered them. 66 00:04:21,680 --> 00:04:23,513 You sure this is safe? 67 00:04:25,968 --> 00:04:27,620 What they actually are. 68 00:04:27,620 --> 00:04:30,484 The 13 vitamins can be divided into two teams. 69 00:04:30,484 --> 00:04:32,817 How we learnt to build them. 70 00:04:33,720 --> 00:04:35,844 Tonight, Walgreens and Target have pulled 71 00:04:35,844 --> 00:04:37,740 the products nationwide. 72 00:04:37,740 --> 00:04:39,128 And how safe they are. 73 00:04:39,128 --> 00:04:40,947 All vitamins, all nutrients, 74 00:04:40,947 --> 00:04:43,590 they are toxic in high amounts. 75 00:04:43,590 --> 00:04:45,556 We gotta start taking these seriously as we should with 76 00:04:45,556 --> 00:04:47,511 every chemical we put into our bodies. 77 00:04:47,511 --> 00:04:49,689 You shouldn't assume it's safe and you shouldn't assume 78 00:04:49,689 --> 00:04:51,400 it's beneficial. 79 00:04:51,400 --> 00:04:53,675 Currently we don't know about the long term ethics 80 00:04:53,675 --> 00:04:55,691 of diet supplements. 81 00:04:55,691 --> 00:04:57,243 I'm a scientist. 82 00:04:57,243 --> 00:05:01,669 I'm also a father and I want to know how do I do the best 83 00:05:01,669 --> 00:05:06,419 for my son, and one day, might he be taking vitamin pills 84 00:05:07,644 --> 00:05:08,477 to Mars? 85 00:05:09,596 --> 00:05:12,763 (engine blasting off) 86 00:05:13,741 --> 00:05:16,485 Across the word, some experts claim that taking vitamins 87 00:05:16,485 --> 00:05:19,558 can be life savers, whereas others argue that it's just 88 00:05:19,558 --> 00:05:22,882 a waste of time or even dangerous, so how are we supposed 89 00:05:22,882 --> 00:05:26,130 to know whether the take them or not? 90 00:05:26,130 --> 00:05:28,880 (dramatic music) 91 00:05:37,367 --> 00:05:40,450 (train bell ringing) 92 00:05:48,800 --> 00:05:52,381 Over a billion of us take at least one vitamin or supplement 93 00:05:52,381 --> 00:05:54,454 hoping to keep as healthy as possible 94 00:05:54,454 --> 00:05:56,434 for as long as possible, 95 00:05:56,434 --> 00:06:00,495 but most of us know nothing about them. 96 00:06:00,495 --> 00:06:04,320 This ordinary meal contains almost every single essential 97 00:06:04,320 --> 00:06:05,894 vitamin and nutrient we need. 98 00:06:05,894 --> 00:06:08,728 There are vitamins A, B, and K in the lettuce, lots of 99 00:06:08,728 --> 00:06:12,438 vitamin Bs in the chicken, vitamin C in the tomato, K in 100 00:06:12,438 --> 00:06:15,886 the cucumber, vitamin D in the egg yolk? 101 00:06:15,886 --> 00:06:18,760 There are even vitamins in your coffee and that's before 102 00:06:18,760 --> 00:06:19,615 you add the milk. 103 00:06:19,615 --> 00:06:23,684 In fact, this meal contains every single one of these but 104 00:06:23,684 --> 00:06:26,667 what are these exactly and what are they doing to 105 00:06:26,667 --> 00:06:30,417 our bodies, and how much do we actually need? 106 00:06:33,640 --> 00:06:36,798 Around 100 years ago, we didn't even know that vitamins 107 00:06:36,798 --> 00:06:37,631 existed. 108 00:06:38,609 --> 00:06:43,609 We knew we needed protein, carbohydrate, fat, and minerals 109 00:06:44,420 --> 00:06:46,982 and some suspected there were other vital substances 110 00:06:46,982 --> 00:06:49,399 in food but they had no name. 111 00:06:51,761 --> 00:06:54,620 And then in 1911, a Polish chemist began some important 112 00:06:54,620 --> 00:06:58,443 experiments with some unfortunate pigeons and he changed 113 00:06:58,443 --> 00:07:00,490 the course of history. 114 00:07:00,490 --> 00:07:02,990 His name was Dr. Casimir Funk. 115 00:07:04,117 --> 00:07:09,117 ♪ It must have been some flash of inspiration ♪ 116 00:07:09,655 --> 00:07:14,655 ♪ Rendered scientifically precise ♪ 117 00:07:15,397 --> 00:07:20,397 ♪ Conclusions that he drew from observation ♪ 118 00:07:21,576 --> 00:07:26,576 ♪ Feeding pigeons different types of rice ♪ 119 00:07:26,698 --> 00:07:29,688 ♪ He said some get sick ♪ 120 00:07:29,688 --> 00:07:32,431 ♪ Some get well ♪ 121 00:07:32,431 --> 00:07:37,431 ♪ It ain't no germ or virus, not as far as I can tell ♪ 122 00:07:38,130 --> 00:07:43,130 ♪ There's something else inside that feed ♪ 123 00:07:43,796 --> 00:07:46,396 ♪ It isn't something bad they get ♪ 124 00:07:46,396 --> 00:07:49,474 ♪ It's something good they need ♪ 125 00:07:49,474 --> 00:07:53,920 ♪ Thank you Dr. Funk ♪ 126 00:07:53,920 --> 00:07:57,587 ♪ For helping us understand ♪ 127 00:07:59,121 --> 00:08:01,568 At the turn of the 20th century, millions of people were 128 00:08:01,568 --> 00:08:04,823 suffering from diseases rarely seen today, things like 129 00:08:04,823 --> 00:08:08,710 beri beri, pellagra, rickets, and scurvy. 130 00:08:08,710 --> 00:08:09,548 Now, the thinking at the time was that it was the 131 00:08:09,548 --> 00:08:12,859 presence of something bad that made us sick, germs and 132 00:08:12,859 --> 00:08:15,420 toxins were all the range. 133 00:08:15,420 --> 00:08:17,632 ♪ It all comes down to the (mumbles) aminos ♪ 134 00:08:17,632 --> 00:08:19,284 ♪ Casimir Funk is ♪ 135 00:08:19,284 --> 00:08:22,878 When Funk fed his pigeons white rice, starch, or sugar, 136 00:08:22,878 --> 00:08:24,211 they became ill. 137 00:08:25,357 --> 00:08:28,509 But fed brown rice, they recovered. 138 00:08:28,509 --> 00:08:31,378 So Funk wanted to identify the substance in the brown rice 139 00:08:31,378 --> 00:08:32,711 that cured them. 140 00:08:34,893 --> 00:08:37,950 Now, Funk didn't know where this mystery substance actually 141 00:08:37,950 --> 00:08:40,822 was but he invented a word to describe it, from the Latin 142 00:08:40,822 --> 00:08:44,440 vita, meaning life, and amine, containing nitrogen. 143 00:08:44,440 --> 00:08:46,831 Later, the E was dropped in English, so the word 144 00:08:46,831 --> 00:08:48,234 became vitamin. 145 00:08:48,234 --> 00:08:52,308 Dr. Funk invented a catchy word that captured a fresh idea. 146 00:08:52,308 --> 00:08:55,160 There was a new family of nutrients, the absence of which 147 00:08:55,160 --> 00:08:56,826 caused disease. 148 00:08:56,826 --> 00:08:59,314 Soon it became evident that they were not all amines, 149 00:08:59,314 --> 00:09:01,169 but the name stuck and the word vitamin 150 00:09:01,169 --> 00:09:04,752 became famous, taking on a life of its own. 151 00:09:08,435 --> 00:09:11,518 ♪ Thank you Dr. Funk ♪ 152 00:09:13,646 --> 00:09:17,373 Over the next few decades, all 13 vitamins were identified. 153 00:09:17,373 --> 00:09:20,697 Soon, they were synthesized and turned into pills. 154 00:09:20,697 --> 00:09:23,787 Little did Dr. Funk realize, his vitamins would spawn 155 00:09:23,787 --> 00:09:27,350 100 billion dollar a year industry. 156 00:09:27,350 --> 00:09:28,702 Vitamania had begun. 157 00:09:31,140 --> 00:09:34,450 ♪ Thank you Dr. Funk ♪ 158 00:09:34,450 --> 00:09:38,200 ♪ Casimir Funk, Casimir Funk ♪ 159 00:09:40,461 --> 00:09:43,440 (lively music) 160 00:09:45,288 --> 00:09:48,990 I've come here to one of the largest nutritional trade 161 00:09:48,990 --> 00:09:49,349 shows on Earth. 162 00:09:58,677 --> 00:10:02,106 They're expecting tens of thousands of people, all buying 163 00:10:02,106 --> 00:10:05,700 and selling the latest and greatest in vitamins and dietary 164 00:10:05,700 --> 00:10:06,700 supplements. 165 00:10:07,115 --> 00:10:09,615 I want to see what's on offer. 166 00:10:14,284 --> 00:10:16,879 After about four days, you really feel all the brain 167 00:10:16,879 --> 00:10:20,466 health benefits, so cognitive support, memory support, 168 00:10:20,466 --> 00:10:22,260 amazing sleep. 169 00:10:22,260 --> 00:10:25,404 Historically, silver's known to be antiviral, antifungal, 170 00:10:25,404 --> 00:10:28,268 antibacterial to build your immune system by potentiating 171 00:10:28,268 --> 00:10:29,553 your white blood cell count. 172 00:10:29,553 --> 00:10:32,836 They're organic botanical source vitamins and instead of 173 00:10:32,836 --> 00:10:35,568 putting them in isolated sugar syrups, we put them 174 00:10:35,568 --> 00:10:36,651 in more food. 175 00:10:41,433 --> 00:10:44,352 Vitamins have managed to develop this halo around them 176 00:10:44,352 --> 00:10:48,307 where everything the word vitamin touches seems like it 177 00:10:48,307 --> 00:10:51,678 should be both miraculous and safe. 178 00:10:51,678 --> 00:10:53,721 Science journalist Catherine Price spent 179 00:10:53,721 --> 00:10:57,170 five years investigating vitamins. 180 00:10:57,170 --> 00:10:59,912 We tend to think of vitamins and supplements as this kind 181 00:10:59,912 --> 00:11:02,221 of home grown industry of people gathering herbs in their 182 00:11:02,221 --> 00:11:04,194 backyards and boiling oranges 183 00:11:04,194 --> 00:11:05,978 for vitamin C and it's actually 184 00:11:05,978 --> 00:11:08,145 a 40 billion dollar a year industry 185 00:11:08,145 --> 00:11:10,570 in the US and 100 billion dollars 186 00:11:10,570 --> 00:11:13,751 around the world and it's growing rapidly. 187 00:11:13,751 --> 00:11:15,864 Who is taking vitamins? 188 00:11:15,864 --> 00:11:17,636 More than half of Americans are taking some kind of 189 00:11:17,636 --> 00:11:22,329 supplement and ironically, that half is often the healthier 190 00:11:22,329 --> 00:11:25,171 half of the American population. 191 00:11:25,171 --> 00:11:27,350 You have to have a certain amount of awareness and interest 192 00:11:27,350 --> 00:11:30,904 in health to go out and buy these products. 193 00:11:30,904 --> 00:11:34,179 It has omega-369 and it's the only sauce of omega-7 194 00:11:34,179 --> 00:11:36,950 in the plant sauce world. 195 00:11:36,950 --> 00:11:39,400 All of our multi-vitamins have a base of omega-3 196 00:11:39,400 --> 00:11:43,281 fish oil, multi-vitamin as well as vitamins E12 and D3. 197 00:11:43,281 --> 00:11:46,674 C, D, E, all your B vitamins. 198 00:11:46,674 --> 00:11:49,651 Folic acid, you name it, it's in there. 199 00:11:49,651 --> 00:11:53,192 Most vitamins are self prescribed. 200 00:11:53,192 --> 00:11:56,150 They're not recommended by a doctor. 201 00:11:56,150 --> 00:11:57,824 So we should know that the biggest category for 202 00:11:57,824 --> 00:12:00,331 vitamins is multi-vitamins. 203 00:12:00,331 --> 00:12:03,379 Most of us, not all of us, have been taught from a young age 204 00:12:03,379 --> 00:12:05,754 they're something that you take just in case. 205 00:12:05,754 --> 00:12:07,914 Just in case you don't get enough fruits and vegetables 206 00:12:07,914 --> 00:12:10,912 from your diet, just take the multi-vitamin. 207 00:12:10,912 --> 00:12:12,790 And I think when you talk about vitamins, a big part of the 208 00:12:12,790 --> 00:12:14,746 psychology is hope. 209 00:12:14,746 --> 00:12:17,412 What you're looking at right here is a powdered magnesium 210 00:12:17,412 --> 00:12:18,711 citrate formula. 211 00:12:18,711 --> 00:12:21,669 We have an adrenal fatigue formula that has a very heavy 212 00:12:21,669 --> 00:12:23,335 B-complex. 213 00:12:23,335 --> 00:12:25,773 These are biological response modifiers. 214 00:12:25,773 --> 00:12:28,121 Are there like vitamins in here? 215 00:12:28,121 --> 00:12:29,783 Yeah, there's-- 216 00:12:29,783 --> 00:12:30,841 Some? 217 00:12:30,841 --> 00:12:34,710 Then, Catherine told me something I found staggering. 218 00:12:34,710 --> 00:12:36,755 How are vitamins regulated? 219 00:12:36,755 --> 00:12:38,711 Vitamins are not regulated the way that you would think 220 00:12:38,711 --> 00:12:40,468 they would be. 221 00:12:40,468 --> 00:12:43,514 Technically, the FDA is in control of them, but all of 222 00:12:43,514 --> 00:12:46,536 these products around us, all of the 85 thousand dietary 223 00:12:46,536 --> 00:12:49,356 supplement products on the shelves, 224 00:12:49,356 --> 00:12:52,446 none of them are required to be tested for safety 225 00:12:52,446 --> 00:12:55,235 or for efficacy before they're sold. 226 00:12:55,235 --> 00:12:56,585 So not at all. 227 00:12:56,585 --> 00:13:00,371 The FDA cannot require any of these companies to test them 228 00:13:00,371 --> 00:13:02,658 to make sure they do what they say or that they're not 229 00:13:02,658 --> 00:13:04,794 going to hurt you. 230 00:13:04,794 --> 00:13:07,730 And it's not just the US. 231 00:13:07,730 --> 00:13:10,437 In Australia and Europa as well, they're not required to be 232 00:13:10,437 --> 00:13:12,937 tested for safety before sale. 233 00:13:13,909 --> 00:13:16,591 But what about kid's vitamins? 234 00:13:16,591 --> 00:13:18,542 Children's vitamins are regulated the same way adult 235 00:13:18,542 --> 00:13:20,471 vitamins are, which is to say they're not required to be 236 00:13:20,471 --> 00:13:23,815 tested for safety or for efficacy before they're sold. 237 00:13:23,815 --> 00:13:26,323 So what you're giving your child doesn't have 238 00:13:26,323 --> 00:13:27,406 to be tested? 239 00:13:28,785 --> 00:13:29,702 So nothing? 240 00:13:30,572 --> 00:13:31,405 No. 241 00:13:35,985 --> 00:13:39,189 Never in history have we had the ability to manipulate 242 00:13:39,189 --> 00:13:42,573 our nutrition in such extraordinary ways, but how do we know 243 00:13:42,573 --> 00:13:45,752 if what we're doing is a good idea or not? 244 00:13:45,752 --> 00:13:49,910 I'm a scientist, my background is in physics, and so I have 245 00:13:49,910 --> 00:13:51,723 a bias towards evidence and I'm skeptical of some of the 246 00:13:51,723 --> 00:13:54,464 marketing claims made here, but I'm trying to keep an open 247 00:13:54,464 --> 00:13:57,985 mind, after all, there have been at least 10 Nobel prizes 248 00:13:57,985 --> 00:14:01,775 awarded for vitamin science, so I'm in search of a deeper 249 00:14:01,775 --> 00:14:05,168 understanding and I want to start with the basics, like 250 00:14:05,168 --> 00:14:07,335 what exactly is a vitamin? 251 00:14:09,268 --> 00:14:12,180 (peaceful music) 252 00:14:15,615 --> 00:14:19,865 Vitamins are chemicals that are essential for life. 253 00:14:21,598 --> 00:14:25,150 Without them, we get sick and we can die. 254 00:14:28,945 --> 00:14:32,421 Our bodies can't make vitamins by themselves, so we usually 255 00:14:32,421 --> 00:14:35,170 get them from our food. 256 00:14:35,170 --> 00:14:38,141 So far, 13 vitamins have been identified and although they 257 00:14:38,141 --> 00:14:41,965 share a name, these are very different molecules and they 258 00:14:41,965 --> 00:14:44,450 do very different things. 259 00:14:44,450 --> 00:14:47,330 (bright music) 260 00:14:48,670 --> 00:14:51,872 ♪ Hey, hey, I'm vitamin A ♪ 261 00:14:51,872 --> 00:14:55,896 ♪ The first vitamin on display ♪ 262 00:14:55,896 --> 00:14:59,829 ♪ When you open your eyes, I help you see the light ♪ 263 00:14:59,829 --> 00:15:04,279 ♪ When the germs arise, I'm gonna teach you to fight ♪ 264 00:15:04,279 --> 00:15:07,608 ♪ Here we come, we're the vitamin Bs ♪ 265 00:15:07,608 --> 00:15:10,926 ♪ We're a great big family ♪ 266 00:15:10,926 --> 00:15:14,297 ♪ So much energy you can gain ♪ 267 00:15:14,297 --> 00:15:17,946 ♪ For your metabolism and your genes and your brain ♪ 268 00:15:17,946 --> 00:15:22,946 ♪ One two three five six seven nine 12, the Bs ♪ 269 00:15:23,646 --> 00:15:27,204 ♪ Howdy folks, they call me vitamin C ♪ 270 00:15:27,204 --> 00:15:28,446 ♪ Vitamin C ♪ 271 00:15:28,446 --> 00:15:33,446 ♪ I'm a healer and protector and I can almost guarantee ♪ 272 00:15:34,520 --> 00:15:39,520 ♪ You're impervious to scurvy if you get your share of me ♪ 273 00:15:39,906 --> 00:15:44,906 ♪ Vitamin C, vitamin C, vitamin C ♪ 274 00:15:47,157 --> 00:15:52,157 ♪ I think it's unfair, it almost seems cruel ♪ 275 00:15:54,378 --> 00:15:59,378 ♪ To come from the sun and still be so cool ♪ 276 00:16:01,600 --> 00:16:05,645 ♪ Warmest regards, vitamin D ♪ 277 00:16:05,645 --> 00:16:08,170 ♪ Yeah ♪ 278 00:16:08,170 --> 00:16:13,170 ♪ Well, babe I know sometimes it's hard to recognize ♪ 279 00:16:13,762 --> 00:16:18,762 ♪ When you need some help to antioxidize ♪ 280 00:16:19,222 --> 00:16:23,584 ♪ So stop those radicals from running wild and free ♪ 281 00:16:23,584 --> 00:16:28,584 ♪ Look to me, E ♪ 282 00:16:29,718 --> 00:16:32,481 ♪ Hey I'm K, there's something I'd say, I keep your body ♪ 283 00:16:32,481 --> 00:16:34,679 ♪ Rocking in a critical way ♪ 284 00:16:34,679 --> 00:16:37,430 ♪ A well known cornerstone for your blood and bone ♪ 285 00:16:37,430 --> 00:16:40,730 ♪ I can't do it alone, you need all the crew, the whole ♪ 286 00:16:40,730 --> 00:16:43,370 ♪ Retinue, props to do because that's how you grew ♪ 287 00:16:43,370 --> 00:16:45,682 ♪ And that's what you need to get through the day, ♪ 288 00:16:45,682 --> 00:16:49,849 ♪ Talk about vitamins A through K ♪ 289 00:16:55,971 --> 00:16:58,967 The 13 vitamins can be divided into two teams, the water 290 00:16:58,967 --> 00:17:02,991 soluble team consisting of all the B vitamins and vitamin C 291 00:17:02,991 --> 00:17:04,224 and the fat soluble team, 292 00:17:04,224 --> 00:17:07,746 consisting of A, D, E, and K, ADEK. 293 00:17:07,746 --> 00:17:10,600 So why does this matter? 294 00:17:10,600 --> 00:17:12,838 Well, we can get rid of excess water soluble vitamins 295 00:17:12,838 --> 00:17:15,566 in our urine, but the fat soluble ones are stored in our 296 00:17:15,566 --> 00:17:18,808 livers and fatty tissue, so they're the ones that can 297 00:17:18,808 --> 00:17:21,475 build up easily to toxic levels. 298 00:17:23,658 --> 00:17:26,440 What does a food data miner do? 299 00:17:26,440 --> 00:17:28,406 So essentially, I'm looking at all 300 00:17:28,406 --> 00:17:31,807 these different kind of (mumbles) foods. 301 00:17:31,807 --> 00:17:33,693 Someone who's an expert in the vitamins in our 302 00:17:33,693 --> 00:17:36,776 food is dietician Dr. Yasmine Probst. 303 00:17:38,441 --> 00:17:42,777 If I could see the amount of vitamins that I need every day, 304 00:17:42,777 --> 00:17:44,123 it would look like this? 305 00:17:44,123 --> 00:17:44,956 That's right, 306 00:17:44,956 --> 00:17:45,789 that's a very close representation 307 00:17:45,789 --> 00:17:48,328 to what we need, they're tiny. 308 00:17:48,328 --> 00:17:49,523 There's hardly anything here. 309 00:17:49,523 --> 00:17:50,684 Exactly. 310 00:17:50,684 --> 00:17:52,440 They're a speck on this plate here. 311 00:17:52,440 --> 00:17:54,633 Yeah, like vitamin D there, nearly invisible. 312 00:17:54,633 --> 00:17:56,640 Yeah, exactly. 313 00:17:56,640 --> 00:17:59,390 It just looks like a few pinches of salt or spice. 314 00:17:59,390 --> 00:18:02,500 Yeah, so it might be about the size of say, a poppy seed 315 00:18:02,500 --> 00:18:06,714 or something really tiny that people see on a regular basis. 316 00:18:06,714 --> 00:18:09,559 So in order to get all the vitamins I need in a day, this 317 00:18:09,559 --> 00:18:11,400 is the food I need to eat? 318 00:18:11,400 --> 00:18:14,587 That's right, that's right, not very many foods at all. 319 00:18:14,587 --> 00:18:18,110 But I would eat this in one meal, this looks like dinner 320 00:18:18,110 --> 00:18:19,338 and dessert to me. 321 00:18:19,338 --> 00:18:21,273 Well, this is the amount that you would need as an 322 00:18:21,273 --> 00:18:22,732 average adult male. 323 00:18:22,732 --> 00:18:25,134 Some people imagine you need to eat a giant mound 324 00:18:25,134 --> 00:18:27,875 of food, you know like a pile of spinach to get the vitamins 325 00:18:27,875 --> 00:18:31,114 that you need in a day, but it's really not that much. 326 00:18:31,114 --> 00:18:33,137 Well, I guess there's a little bit of confusion out there. 327 00:18:33,137 --> 00:18:35,317 People think that the amount of food that you need are 328 00:18:35,317 --> 00:18:38,352 these really big numbers but it's really not that much 329 00:18:38,352 --> 00:18:41,540 and it's more about eating the right foods in the right 330 00:18:41,540 --> 00:18:44,686 balance so that you get the right nutrients that you need. 331 00:18:44,686 --> 00:18:47,693 One carrot gives me all I would need of vitamin A. 332 00:18:47,693 --> 00:18:51,129 That's right, one medium carrot. 333 00:18:51,129 --> 00:18:53,918 When we eat a carrot, vitamins are released 334 00:18:53,918 --> 00:18:58,751 into the bloodstream, beginning a complex molecular dance. 335 00:18:59,593 --> 00:19:00,843 Take vitamin A. 336 00:19:01,811 --> 00:19:05,956 Our body makes it from a plant chemical called beta carotene 337 00:19:05,956 --> 00:19:09,637 and transforms it into forms of vitamin A that are essential 338 00:19:09,637 --> 00:19:14,637 for sight, immune function, and even how an embryo develops. 339 00:19:16,439 --> 00:19:20,523 Each of the vitamins trigger amazing chemical reactions, 340 00:19:20,523 --> 00:19:24,606 and together, they impact every part of our body. 341 00:19:25,610 --> 00:19:30,523 We can't hear, smell, think, touch, taste, breathe 342 00:19:30,523 --> 00:19:33,100 without these 13 vitamins, 343 00:19:33,100 --> 00:19:36,751 they don't just keep us alive, they are life. 344 00:19:38,417 --> 00:19:42,384 And when it's all working well, it's a wonder. 345 00:19:42,384 --> 00:19:47,384 But when we don't have enough, when there are deficiencies, 346 00:19:47,541 --> 00:19:49,541 the body's systems fail. 347 00:19:54,829 --> 00:19:58,106 I noticed that I was getting very tired. 348 00:19:58,106 --> 00:20:01,105 Weakness, blood was coming out through the side of the 349 00:20:01,105 --> 00:20:04,855 teeth and stuff and it started getting worse. 350 00:20:07,475 --> 00:20:12,223 And then I also noticed that I was sleeping a lot. 351 00:20:12,223 --> 00:20:17,223 Now, I'm talking about from six in the afternoon all the way 352 00:20:18,251 --> 00:20:21,418 'til 10 in the morning, I mean, a lot. 353 00:20:22,770 --> 00:20:25,884 And so that kind of scared me, so I knew something 354 00:20:25,884 --> 00:20:30,134 was wrong, so that's why I'm glad I went and I seen 355 00:20:31,244 --> 00:20:32,654 Dr. Churchill. 356 00:20:32,654 --> 00:20:35,321 (intense music) 357 00:20:42,464 --> 00:20:45,128 Sonny Lopez had a disease that no one had 358 00:20:45,128 --> 00:20:49,696 thought to look for, let alone test for for decades, 359 00:20:49,696 --> 00:20:52,113 and he wasn't the first case. 360 00:20:55,730 --> 00:21:00,730 So the first patient came in with painful, bruisy rash 361 00:21:00,252 --> 00:21:04,296 on both of his legs and general joint pains and fatigue 362 00:21:04,296 --> 00:21:08,988 and other systems and he had been treated for what they 363 00:21:08,988 --> 00:21:12,425 thought was an infection of the legs with no improvement, 364 00:21:12,425 --> 00:21:16,576 people were looking for blood clots and other things and all 365 00:21:16,576 --> 00:21:19,873 of the tests were coming up negative. 366 00:21:19,873 --> 00:21:23,400 Someone thought to ask about his diet. 367 00:21:24,345 --> 00:21:27,774 They found that he had been eating nothing but white bread 368 00:21:27,774 --> 00:21:31,879 and American cheese for the last several years. 369 00:21:31,879 --> 00:21:36,200 No fruits, no vegetables, nothing that would provide you 370 00:21:36,200 --> 00:21:41,200 with the basic level of nutrition that you would need. 371 00:21:41,840 --> 00:21:43,975 Then, with that kind of nutritional problem, maybe we should 372 00:21:43,975 --> 00:21:48,250 check some vitamin levels and his vitamin C level came back 373 00:21:48,250 --> 00:21:51,809 at absolutely undetectable, level of zero. 374 00:21:51,809 --> 00:21:54,282 Dr. Eric Churchill was stunned. 375 00:21:54,282 --> 00:21:57,920 He realized the patients had a disease common more than 376 00:21:57,920 --> 00:21:59,675 100 years ago, they had scurvy. 377 00:22:01,643 --> 00:22:03,944 This is something you hear about with pirates in the 378 00:22:03,944 --> 00:22:07,414 18th century, it's just not a disease that we thought 379 00:22:07,414 --> 00:22:08,997 people had anymore. 380 00:22:10,110 --> 00:22:12,761 (dramatic music) 381 00:22:19,680 --> 00:22:22,666 Scurvy was absolutely devastating 382 00:22:22,666 --> 00:22:27,660 it's been estimated that between the late 1400s and early 383 00:22:27,660 --> 00:22:30,862 1800s, two million sailors perished as a result 384 00:22:30,862 --> 00:22:32,195 of this disease. 385 00:22:33,185 --> 00:22:35,275 It's harder than I expected. 386 00:22:35,275 --> 00:22:37,942 Medical historian Dr. John Waller has studied the links 387 00:22:37,942 --> 00:22:39,942 between scurvy and diet. 388 00:22:41,261 --> 00:22:43,820 So this is a typical daily ration for a sailor in the 389 00:22:43,820 --> 00:22:48,820 royal navy in the 18th century, about a pound of very hard 390 00:22:48,915 --> 00:22:50,516 ship's biscuit. 391 00:22:50,516 --> 00:22:52,813 Then they would get something like half a pint 392 00:22:52,813 --> 00:22:53,980 of dried peas. 393 00:22:55,330 --> 00:22:59,704 Then salted meat, and it would be washed down with something 394 00:22:59,704 --> 00:23:01,324 like a gallon of beer every day. 395 00:23:01,324 --> 00:23:04,156 But there was something missing from their diet. 396 00:23:04,156 --> 00:23:07,790 Yeah, there's something very, very significant missing. 397 00:23:07,790 --> 00:23:09,746 And that of course is vitamin C. 398 00:23:10,915 --> 00:23:12,715 The thought that certain foods might 399 00:23:12,715 --> 00:23:14,859 cure scurvy wasn't a new one. 400 00:23:14,859 --> 00:23:18,731 It was an old idea that had been discovered and forgotten 401 00:23:18,731 --> 00:23:19,648 many times. 402 00:23:20,866 --> 00:23:25,393 Every so often, somebody would try citrus fruits. 403 00:23:25,393 --> 00:23:28,790 The sailors would make what appeared to be a miraculous 404 00:23:28,790 --> 00:23:32,790 recovery, but it never became standard practice. 405 00:23:33,292 --> 00:23:34,867 So how did they eventually figure out 406 00:23:34,867 --> 00:23:36,375 how to cure scurvy? 407 00:23:36,375 --> 00:23:38,315 It happened very gradually, but there were a few 408 00:23:38,315 --> 00:23:40,560 really critical moments. 409 00:23:40,560 --> 00:23:44,893 One of them took place in 1747, when a Scottish born 410 00:23:45,961 --> 00:23:50,260 ship's surgeon ran what is the first controlled 411 00:23:50,260 --> 00:23:52,927 clinical trial in human history. 412 00:23:54,742 --> 00:23:58,690 Dr. James Lind had seen the horrors of scurvy 413 00:23:58,690 --> 00:23:59,417 firsthand. 414 00:23:59,417 --> 00:24:02,682 Usually the ship's surgeon would try a range of supposed 415 00:24:02,682 --> 00:24:07,461 remedies and hope for the best, but Lind came up with a 416 00:24:07,461 --> 00:24:08,378 novel idea. 417 00:24:09,658 --> 00:24:14,177 He took 12 men with scurvy and split them into pairs. 418 00:24:14,177 --> 00:24:16,490 Each pair was given ship's rations plus one of the 419 00:24:16,490 --> 00:24:19,450 supposed cures of the time. 420 00:24:19,450 --> 00:24:22,950 Cider, vinegar, seawater, something called 421 00:24:24,385 --> 00:24:29,385 "elixir of vitriol" made from sulfuric acid, a concoction 422 00:24:29,602 --> 00:24:33,352 of garlic and mustard, or oranges and lemons. 423 00:24:36,920 --> 00:24:40,140 The two sailors who had been receiving the citrus fruits 424 00:24:40,140 --> 00:24:43,250 had made a really remarkable recovery. 425 00:24:43,250 --> 00:24:47,497 Now, the two who had received cider were somewhat improved. 426 00:24:47,497 --> 00:24:50,864 The rest, they had continued to deteriorate and they were 427 00:24:50,864 --> 00:24:53,139 fast on the way to dying. 428 00:24:53,139 --> 00:24:57,478 So this experiment had allowed him to arrive at a really 429 00:24:57,478 --> 00:25:02,172 clear conclusion, that fresh fruits and vegetables 430 00:25:02,172 --> 00:25:05,757 really can be used to cure scurvy. 431 00:25:05,757 --> 00:25:08,589 How significant would you consider Lind's experiment? 432 00:25:08,589 --> 00:25:11,602 There's no question that this single discovery saved 433 00:25:11,602 --> 00:25:15,360 millions of lives, but there's a broader and every bit as 434 00:25:15,360 --> 00:25:20,183 enduring effect of Lind's work and that is the way in which 435 00:25:20,183 --> 00:25:23,988 controlled clinical trial eventually becomes orthodoxy 436 00:25:23,988 --> 00:25:24,988 in medicine. 437 00:25:26,124 --> 00:25:29,735 It's a species altering development. 438 00:25:29,735 --> 00:25:33,600 Humans had unlocked the way to identify 439 00:25:33,600 --> 00:25:34,810 what cures will work. 440 00:25:36,272 --> 00:25:39,104 When Lind goes to publish his findings a few years later, 441 00:25:39,104 --> 00:25:42,405 he buries the information in a few paragraphs 200 pages 442 00:25:42,405 --> 00:25:44,844 into his 400 page book. 443 00:25:44,844 --> 00:25:47,442 It's as though not even Lind realizes the significance 444 00:25:47,442 --> 00:25:50,146 of his own discovery, and it may have been forgotten 445 00:25:50,146 --> 00:25:53,820 yet again if not for the work of a young doctor Gilbert 446 00:25:53,820 --> 00:25:56,567 Blain who manages to convince the British navy to supply 447 00:25:56,567 --> 00:25:58,733 lemon juice to its sailors. 448 00:25:58,733 --> 00:26:00,150 The year is 1795. 449 00:26:01,755 --> 00:26:05,117 That's one year after Lind's death and 48 years after his 450 00:26:05,117 --> 00:26:07,338 historic experiment. 451 00:26:07,338 --> 00:26:10,171 (whimsical music) 452 00:26:11,323 --> 00:26:15,504 With lemons and later limes as their secret weapon, 453 00:26:15,504 --> 00:26:20,140 the British navy emerged as the strongest on the globe. 454 00:26:20,140 --> 00:26:24,410 The supply of fruit shaped the destiny of nations, allowing 455 00:26:24,410 --> 00:26:28,811 us to venture out across the seas, to live and to thrive 456 00:26:28,811 --> 00:26:31,311 fueled by the right nutrition. 457 00:26:37,216 --> 00:26:40,502 But today, it seems that knowledge is being forgotten 458 00:26:40,502 --> 00:26:41,942 once again. 459 00:26:41,942 --> 00:26:43,647 How many people live here? 460 00:26:43,647 --> 00:26:45,389 I'd say about 15. 461 00:26:45,389 --> 00:26:47,142 And how long you been living here? 462 00:26:47,142 --> 00:26:48,809 Five years, Derek. 463 00:26:48,809 --> 00:26:50,571 That's a pretty long time. 464 00:26:50,571 --> 00:26:52,321 Yes, it is. 465 00:26:55,734 --> 00:26:57,688 This is my castle right here. 466 00:26:57,688 --> 00:26:58,521 Wow. 467 00:27:01,458 --> 00:27:04,854 This is my family, this is everybody I love. 468 00:27:04,854 --> 00:27:07,271 That's me back when I was 21. 469 00:27:08,523 --> 00:27:10,500 You had a lot of hair back then. 470 00:27:10,500 --> 00:27:12,705 Yes, that was back in the hippie days, you know? 471 00:27:12,705 --> 00:27:14,270 It's a beautiful family. 472 00:27:14,270 --> 00:27:14,860 Thanks. 473 00:27:16,110 --> 00:27:19,175 This is all the stuff, this is where I keep my cereal, 474 00:27:19,175 --> 00:27:21,175 my bread, peanut butter. 475 00:27:23,330 --> 00:27:26,541 Refrigerate down the hall here, come on, I'll show you. 476 00:27:26,541 --> 00:27:30,374 I like to eat burgers, hot dogs, sodas, cakes, 477 00:27:33,184 --> 00:27:36,818 bad cereals, I'm not gonna lie to you. 478 00:27:36,818 --> 00:27:38,815 I do eat a lot of sugar. 479 00:27:38,815 --> 00:27:42,565 When I have my coffee, 15 sugars, two creams. 480 00:27:44,968 --> 00:27:49,635 Many people who have difficulty affording food tend to 481 00:27:50,478 --> 00:27:54,610 go for food that is high fat, high calorie, 482 00:27:55,165 --> 00:27:57,890 and very filling. 483 00:27:57,890 --> 00:27:59,287 If you have a limited food budget, those are the meals 484 00:27:59,287 --> 00:28:02,933 that will fill you up and will satisfy you more than 485 00:28:02,933 --> 00:28:05,566 eating fruits and vegetables. 486 00:28:05,566 --> 00:28:08,712 Alright doc, how you been? Good, good. 487 00:28:08,712 --> 00:28:11,611 In Sonny's case, he has got a lot of other things to worry 488 00:28:11,611 --> 00:28:15,787 about and for him, making sure to eat enough fruits 489 00:28:15,787 --> 00:28:19,333 and vegetables is very far down on his list. 490 00:28:19,333 --> 00:28:21,539 I thought I had some kind of vicious disease and I was 491 00:28:21,539 --> 00:28:26,456 really, really scared, because that's an ugly word, scurvy. 492 00:28:27,682 --> 00:28:30,744 So once we had diagnosed Sonny with scurvy, 493 00:28:30,744 --> 00:28:34,214 the first thing we did was to give him vitamin C tablets 494 00:28:34,214 --> 00:28:38,860 to correct the deficiency, and then, at a later visit 495 00:28:38,860 --> 00:28:39,578 when he said he was having trouble getting those 496 00:28:39,578 --> 00:28:43,348 supplements, I took out my prescription pad and I wrote 497 00:28:43,348 --> 00:28:47,150 "One orange every day" and handed it to him. 498 00:28:48,788 --> 00:28:51,830 It turned out that Sonny was part of an 499 00:28:51,830 --> 00:28:53,500 extraordinary scurvy cluster. 500 00:28:54,362 --> 00:28:56,886 In the last five years, we've documented 30 cases 501 00:28:56,886 --> 00:28:59,974 of scurvy and as far as I'm aware, that's the largest 502 00:28:59,974 --> 00:29:03,400 collection of scurvy cases in the developed world outside 503 00:29:03,400 --> 00:29:07,389 of some exceptional circumstances like war or refugee 504 00:29:07,389 --> 00:29:09,540 situations. 505 00:29:09,540 --> 00:29:10,954 So is it just an issue of all these people with scurvy 506 00:29:10,954 --> 00:29:12,595 not eating enough? 507 00:29:12,595 --> 00:29:13,772 It's really not. 508 00:29:13,772 --> 00:29:17,206 It's about the quality of the food that you eat. 509 00:29:17,206 --> 00:29:19,811 Over half of the people that we diagnose with scurvy 510 00:29:19,811 --> 00:29:23,946 are actually obese and so they are getting enough calories 511 00:29:23,946 --> 00:29:28,755 in their diet but they are low quality, low nutrition 512 00:29:28,755 --> 00:29:33,292 calories, we use the phrase hypercaloric malnutrition 513 00:29:33,292 --> 00:29:35,964 one of the things about scurvy is that it's really not 514 00:29:35,964 --> 00:29:37,714 difficult to prevent. 515 00:29:38,562 --> 00:29:42,450 This is not a high nutritional bar to reach. 516 00:29:42,450 --> 00:29:44,614 And even something like a handful of ketchup packets 517 00:29:44,614 --> 00:29:48,897 a day contain enough vitamin C to keep you out of scurvy. 518 00:29:48,897 --> 00:29:51,457 Not that I recommend people get all of their vitamin C 519 00:29:51,457 --> 00:29:54,624 from ketchup packets, but it's enough. 520 00:29:56,186 --> 00:29:58,989 Surprisingly, the top vitamin C foods 521 00:29:58,989 --> 00:30:01,235 aren't all citrus. 522 00:30:01,235 --> 00:30:04,780 Kiwi fruit, strawberries, and red peppers are all 523 00:30:04,780 --> 00:30:05,161 rich sources. 524 00:30:09,176 --> 00:30:13,516 But vitamin C is fragile, it degrades with time. 525 00:30:13,516 --> 00:30:16,911 One study showed that left at room temperature, 75 percent 526 00:30:16,911 --> 00:30:21,161 of the vitamin C in an apple can be lost in a week. 527 00:30:22,788 --> 00:30:26,355 So just over time, the nutritional content is going down. 528 00:30:26,355 --> 00:30:29,665 Yeah, it's affected by heat, by light, by storage 529 00:30:29,665 --> 00:30:31,681 conditions, lots of different things. 530 00:30:31,681 --> 00:30:33,375 So what should you do if you want to maximize 531 00:30:33,375 --> 00:30:34,974 your nutrition? 532 00:30:34,974 --> 00:30:37,747 I think keep it fresh, keep it local. 533 00:30:37,747 --> 00:30:40,126 The sooner you pick it and consume it, that's probably 534 00:30:40,126 --> 00:30:40,959 the best. 535 00:30:44,772 --> 00:30:47,372 Fascination with the power of vitamin C 536 00:30:47,372 --> 00:30:50,530 led scientists to isolate it and determine its 537 00:30:50,530 --> 00:30:52,873 chemical structure. 538 00:30:52,873 --> 00:30:56,206 In 1937, this work one two Nobel prizes. 539 00:30:58,766 --> 00:31:01,497 And led to the world's first synthetic 540 00:31:01,497 --> 00:31:03,330 or artificial vitamin. 541 00:31:05,119 --> 00:31:07,380 So where do you think the vitamin C in your pills 542 00:31:07,380 --> 00:31:07,955 comes from? 543 00:31:12,562 --> 00:31:14,917 This is the last remaining manufacturing plant for 544 00:31:14,917 --> 00:31:17,554 vitamin C in the western world. 545 00:31:17,554 --> 00:31:21,980 The vast majority of vitamins produced today are synthetic. 546 00:31:21,980 --> 00:31:24,210 That is, they're man made in chemical factories, and in 547 00:31:24,210 --> 00:31:27,601 general, the goal is to duplicate the exact structure 548 00:31:27,601 --> 00:31:30,118 of the naturally occurring vitamins. 549 00:31:30,118 --> 00:31:32,903 Now, we'd hoped to show you how that's done here, 550 00:31:32,903 --> 00:31:35,329 but after 12 months of negations, we've not been able 551 00:31:35,329 --> 00:31:38,909 to film inside, so instead, to understand how to create 552 00:31:38,909 --> 00:31:42,576 a vitamin, we're gonna have to make our own. 553 00:31:44,780 --> 00:31:46,823 To build a vitamin, you need raw materials. 554 00:31:46,823 --> 00:31:49,490 (truck beeping) 555 00:31:51,570 --> 00:31:53,385 And believe it or not, at least eight vitamins can be 556 00:31:53,385 --> 00:31:56,669 synthetically created from fossil fuel products like 557 00:31:56,669 --> 00:31:57,502 coal tar. 558 00:32:00,500 --> 00:32:03,378 They contain components like acetone, found in nail 559 00:32:03,378 --> 00:32:07,536 polish remover, short chain alkanes, found in petrol, 560 00:32:07,536 --> 00:32:11,625 and various aromatic rings found in (mumbles). 561 00:32:11,625 --> 00:32:15,239 The idea is to rearrange these building blocks into more 562 00:32:15,239 --> 00:32:17,842 complex chemical compounds. 563 00:32:17,842 --> 00:32:22,472 Actually building vitamins, precision matters, as a single 564 00:32:22,472 --> 00:32:24,472 bond can alter function. 565 00:32:27,230 --> 00:32:31,603 Not all synthetic vitamins come from fossil fuels. 566 00:32:31,603 --> 00:32:35,853 For example, if you extract sugars from corn syrup. 567 00:32:38,174 --> 00:32:42,635 Ferment them with bacteria and add a chemical reaction, 568 00:32:42,635 --> 00:32:45,520 you have synthetic vitamin C. 569 00:32:46,896 --> 00:32:49,780 Most synthetic vitamins are chemically identical 570 00:32:49,780 --> 00:32:51,951 to the natural form, but without the fiber 571 00:32:51,951 --> 00:32:55,201 and micronutrients that come with food. 572 00:32:56,840 --> 00:33:00,199 The end result is a vitamin made not by a plant, 573 00:33:00,199 --> 00:33:01,449 but in a plant. 574 00:33:02,784 --> 00:33:05,284 (jazzy music) 575 00:33:06,864 --> 00:33:08,366 It's far more efficient and cheaper 576 00:33:08,366 --> 00:33:11,949 to produce vitamins on an industrial scale. 577 00:33:13,649 --> 00:33:16,512 Today, more than 80 percent of the world's vitamin C is 578 00:33:16,512 --> 00:33:19,641 made in China, and it's pretty hard to work out where all 579 00:33:19,641 --> 00:33:22,429 of the raw materials for vitamins come from but most 580 00:33:22,429 --> 00:33:27,429 are produced unquestionably like this, synthetically. 581 00:33:27,476 --> 00:33:29,835 And then they're sent out across the globe to manufacturing 582 00:33:29,835 --> 00:33:33,847 plants, ready to be turned into vitamin pills. 583 00:33:33,847 --> 00:33:36,347 (jazzy music) 584 00:33:47,449 --> 00:33:50,888 Here in Australia, manufacturers are required to test 585 00:33:50,888 --> 00:33:54,543 raw materials on arrival, to ensure the product is what 586 00:33:54,543 --> 00:33:56,293 it says on the label. 587 00:33:59,226 --> 00:34:01,809 Then, the manufacturing begins. 588 00:34:15,159 --> 00:34:18,320 The raw vitamin material is blended with additives 589 00:34:18,320 --> 00:34:21,520 and binding agents, a different recipe 590 00:34:21,520 --> 00:34:23,520 for a different product. 591 00:34:25,106 --> 00:34:28,472 Given the amount of vitamin needed is generally tiny, 592 00:34:28,472 --> 00:34:32,990 what makes up the rest of the pill? 593 00:34:32,990 --> 00:34:34,999 Well, inactive materials like cellulose, sugars, 594 00:34:34,999 --> 00:34:38,378 or rice flour are often added to provide bulk and to 595 00:34:38,378 --> 00:34:41,461 help the tablets dissolve in the gut. 596 00:34:43,417 --> 00:34:46,403 Colors and flavors can also be added to make the tablets 597 00:34:46,403 --> 00:34:47,653 more palatable. 598 00:34:50,361 --> 00:34:53,450 The manufacturing process is similar for most synthetic 599 00:34:53,450 --> 00:34:57,212 vitamins, depending on the end product being made. 600 00:35:00,739 --> 00:35:04,231 Thousands of generic looking pills then fill containers 601 00:35:04,231 --> 00:35:07,731 and the distinctive packaging takes place. 602 00:35:10,179 --> 00:35:12,396 The vitamins are now branded and they're ready 603 00:35:12,396 --> 00:35:13,896 to hit the market. 604 00:35:21,432 --> 00:35:24,760 It's interesting, if vitamin manufacturers here want to 605 00:35:24,760 --> 00:35:27,426 claim "made in Australia," by law, none of the raw 606 00:35:27,426 --> 00:35:30,593 ingredients actually have to come from this country. 607 00:35:30,593 --> 00:35:32,461 And if you want to claim your product is natural, 608 00:35:32,461 --> 00:35:34,910 well, most of the regulators worldwide haven't defined 609 00:35:34,910 --> 00:35:37,951 what natural means, and so it can say natural on the label 610 00:35:37,951 --> 00:35:41,118 and yet contain synthetic ingredients. 611 00:35:42,891 --> 00:35:44,857 But what if you've never taken a vitamin pill 612 00:35:44,857 --> 00:35:46,400 in your life? 613 00:35:46,400 --> 00:35:48,867 You might think this entire vitamin manufacturing process 614 00:35:48,867 --> 00:35:52,831 is irrelevant to you, but then, you'd be wrong. 615 00:35:52,831 --> 00:35:55,453 It turns out even if you're not popping vitamin pills, 616 00:35:55,453 --> 00:35:58,650 chances are you are ingesting synthetic vitamins because 617 00:35:58,650 --> 00:36:03,400 in at least 95 nations, they're being added to your food. 618 00:36:06,220 --> 00:36:07,803 Eat Wonder Bread! 619 00:36:08,658 --> 00:36:11,960 You want to grow bigger and stronger, don't you? 620 00:36:11,960 --> 00:36:12,443 Golly, sure! 621 00:36:12,443 --> 00:36:13,494 Okay! 622 00:36:13,494 --> 00:36:16,357 A sandwich daily and two slices of Wonder Bread every meal 623 00:36:16,357 --> 00:36:18,863 give you eight elements you need. 624 00:36:18,863 --> 00:36:20,952 Around half the countries on Earth allow the 625 00:36:20,952 --> 00:36:25,200 addition of synthetic vitamins to common food products. 626 00:36:25,200 --> 00:36:27,483 It's called fortification. 627 00:36:27,483 --> 00:36:30,724 That's why you can help yourself grow bigger and stronger 628 00:36:30,724 --> 00:36:32,900 eight ways with Wonder Bread. 629 00:36:32,900 --> 00:36:35,479 So be sure to eat Wonder Bread! 630 00:36:35,479 --> 00:36:38,620 (lively music) 631 00:36:42,302 --> 00:36:44,912 In places like the US and Australia, fortifying 632 00:36:44,912 --> 00:36:48,662 bread flour and margarine is required by law. 633 00:36:51,960 --> 00:36:54,292 And companies often decide to add vitamins, mostly from 634 00:36:54,292 --> 00:36:55,375 the B family. 635 00:36:58,170 --> 00:37:00,629 The B vitamins are sometimes called the pep vitamins, 636 00:37:00,629 --> 00:37:02,402 they help our bodies produce energy and assist 637 00:37:02,402 --> 00:37:03,990 in cell development. 638 00:37:03,990 --> 00:37:06,924 Now, they're all water soluble, like vitamin C, which means 639 00:37:06,924 --> 00:37:09,409 our bodies don't store them, so we have to replenish 640 00:37:09,409 --> 00:37:10,326 them often. 641 00:37:11,369 --> 00:37:14,967 Their discovery and synthesis took over 50 years and led 642 00:37:14,967 --> 00:37:16,634 to six Nobel prizes. 643 00:37:17,476 --> 00:37:20,143 (factory music) 644 00:37:28,416 --> 00:37:31,777 One of the vitamins added to bread is B9, better known 645 00:37:31,777 --> 00:37:35,842 as folate, so why is it being added to my bread? 646 00:37:35,842 --> 00:37:38,425 (all shouting) 647 00:37:54,756 --> 00:37:57,924 At 29, Kim Robins is an international wheelchair 648 00:37:57,924 --> 00:37:59,257 basketball star. 649 00:38:04,633 --> 00:38:08,216 He tours the world, playing professionally. 650 00:38:14,748 --> 00:38:18,605 His body and entire life has been shaped by the power 651 00:38:18,605 --> 00:38:19,438 of folate. 652 00:38:20,532 --> 00:38:23,449 (applause, cheers) 653 00:38:26,630 --> 00:38:30,269 Kim was born with a hemangioma on his back 654 00:38:30,269 --> 00:38:33,760 in the middle of his shoulder blades. 655 00:38:33,760 --> 00:38:38,427 It was a legion which looked a bit like a red birthmark. 656 00:38:39,872 --> 00:38:44,390 We were assured at birth that everything was okay. 657 00:38:52,600 --> 00:38:57,229 And it wasn't until he was six months when flags started 658 00:38:57,229 --> 00:39:00,512 to be raised that perhaps he wasn't meeting all of 659 00:39:00,512 --> 00:39:01,762 his milestones. 660 00:39:02,687 --> 00:39:05,800 After months of tests, Kim was diagnosed 661 00:39:05,800 --> 00:39:07,650 with a neural tube defect. 662 00:39:07,650 --> 00:39:10,641 Effectively, a whole in his spinal column which caused 663 00:39:10,641 --> 00:39:12,580 permanent damage. 664 00:39:14,646 --> 00:39:17,305 Part of my disability is that I have chronic back pain 665 00:39:17,305 --> 00:39:22,550 and that's in my lower back, so I get pain maybe 200, 250 666 00:39:23,990 --> 00:39:24,990 times a day. 667 00:39:25,298 --> 00:39:27,387 It's kind of like a back spasm. 668 00:39:27,387 --> 00:39:29,804 My brain's fully functioning. 669 00:39:31,129 --> 00:39:35,245 I guess it affects my leg function to some extent 670 00:39:35,245 --> 00:39:37,945 so I can walk, not super well, but I can walk 671 00:39:37,945 --> 00:39:39,540 a little bit. 672 00:39:39,540 --> 00:39:41,957 Neural tube defects like Kim's can be caused 673 00:39:41,957 --> 00:39:45,290 by the lack of folate long before birth. 674 00:39:50,288 --> 00:39:53,122 If you eat folate, it's the best kind of diet because 675 00:39:53,122 --> 00:39:57,856 it's actually found richly in leafy green vegetables, 676 00:39:57,856 --> 00:39:59,881 it's found in things like asparagus, it's found in 677 00:39:59,881 --> 00:40:03,930 strawberries, it's found in whole grains, so if you are 678 00:40:03,930 --> 00:40:06,918 eating fruits and vegetables, it's quite likely that you 679 00:40:06,918 --> 00:40:09,585 will have a diet rich in folate. 680 00:40:11,282 --> 00:40:15,418 Folate is very important for both DNA and RNA repair, 681 00:40:15,418 --> 00:40:19,116 but also for the rapid development and multiplication 682 00:40:19,116 --> 00:40:21,973 of cells which is what's happening in the fetus, 683 00:40:21,973 --> 00:40:24,676 so it's essential for that. 684 00:40:24,676 --> 00:40:27,332 Professor Fiona Stanley led the Australian arm 685 00:40:27,332 --> 00:40:30,135 of an international children's study that showed lack of 686 00:40:30,135 --> 00:40:33,609 folate in a mother's diet before she was pregnant could 687 00:40:33,609 --> 00:40:36,806 cause major defects in utero. 688 00:40:36,806 --> 00:40:40,428 If before a woman knows that she's pregnant, the fetus 689 00:40:40,428 --> 00:40:42,909 is starting to form all of its major organs and one of 690 00:40:42,909 --> 00:40:46,616 the earliest, by perhaps the seventh week is the 691 00:40:46,616 --> 00:40:51,616 neural tube which starts as an open little trough and then 692 00:40:52,239 --> 00:40:56,340 starts to zipper up and it zips up and down. 693 00:40:56,340 --> 00:40:59,172 I think of it like a zipper going down and as each link 694 00:40:59,172 --> 00:41:02,653 forms together, that's part of the neural tube forming 695 00:41:02,653 --> 00:41:05,780 and if it misses one link, that's where the neural tube 696 00:41:05,780 --> 00:41:06,411 defect would be. 697 00:41:07,296 --> 00:41:11,419 Mine is up between T2 and T6, which is quite high up and 698 00:41:11,419 --> 00:41:14,257 so my spinal cord's a little bit withered, so some 699 00:41:14,257 --> 00:41:17,697 messages get through and some messages don't 700 00:41:17,697 --> 00:41:20,138 By the time a woman knows she's pregnant, 701 00:41:20,138 --> 00:41:21,863 it can be too late. 702 00:41:21,863 --> 00:41:24,689 So scientists sought a way to get a form of folate into 703 00:41:24,689 --> 00:41:27,585 a food that everyone might eat. 704 00:41:27,585 --> 00:41:31,176 There were lots of debates about what staple food 705 00:41:31,176 --> 00:41:35,783 should be fortified, and of course the one that was 706 00:41:35,783 --> 00:41:38,252 suggested was flour, bread making flour because bread seems 707 00:41:38,252 --> 00:41:40,669 to be such a ubiquitous food. 708 00:41:42,266 --> 00:41:44,480 In 2009, Australian bread was fortified 709 00:41:44,480 --> 00:41:47,313 with folic acid, synthetic folate. 710 00:41:49,821 --> 00:41:53,986 It might be added to all white flour for bread making. 711 00:41:53,986 --> 00:41:57,738 It's the same in the US, Canada, and the UK. 712 00:41:57,738 --> 00:42:01,155 Organic or traditional breads are exempt. 713 00:42:03,304 --> 00:42:06,370 Folic acid supplements are also recommended for women 714 00:42:06,370 --> 00:42:08,370 planning to become pregnant. 715 00:42:09,427 --> 00:42:14,160 I had no idea about folate before I fell pregnant. 716 00:42:14,160 --> 00:42:17,766 I didn't even know about neural tube defects. 717 00:42:19,200 --> 00:42:23,213 How it would have changed things if I'd have had folate 718 00:42:23,213 --> 00:42:25,380 in the early stages, we... 719 00:42:29,865 --> 00:42:32,485 That would have been a huge difference, maybe Kim wouldn't 720 00:42:32,485 --> 00:42:33,568 be like this. 721 00:42:37,620 --> 00:42:41,645 I can't change what's happened, it happened and I can't 722 00:42:43,524 --> 00:42:45,357 blame myself for that. 723 00:42:46,723 --> 00:42:49,640 (players shouting) 724 00:42:51,434 --> 00:42:53,524 With folic acid fortification 725 00:42:53,524 --> 00:42:56,553 and supplementation, the rate of neural tube defects 726 00:42:56,553 --> 00:42:58,553 in Australia has halved. 727 00:43:01,271 --> 00:43:03,127 I think it's pretty cool to be doing something 728 00:43:03,127 --> 00:43:04,127 that I love. 729 00:43:05,972 --> 00:43:08,467 A lot of people ask me "If you could, would you prefer not 730 00:43:08,467 --> 00:43:11,177 "to be in a wheelchair" and I say no because of maybe I 731 00:43:11,177 --> 00:43:13,876 never would have done all the things that I've done and I'm 732 00:43:13,876 --> 00:43:17,630 fairly satisfied with where I am and where I'm going. 733 00:43:17,630 --> 00:43:20,547 (crowd applauding) 734 00:43:31,474 --> 00:43:34,980 Over 4000 neural tube defects occur every 735 00:43:34,980 --> 00:43:38,419 year in the European union, yet fortification is not 736 00:43:38,419 --> 00:43:39,669 mandatory here. 737 00:43:40,695 --> 00:43:44,445 So why is Europe taking a different approach? 738 00:43:46,604 --> 00:43:48,793 (foreign language) 739 00:43:48,793 --> 00:43:52,550 Dr. Mathilde Touvier leads a team of French researchers 740 00:43:52,550 --> 00:43:54,720 investigating the relationships between nutrition 741 00:43:54,720 --> 00:43:56,281 and health. 742 00:43:56,281 --> 00:43:58,370 I'll take that, thank you. 743 00:43:58,370 --> 00:43:59,589 It's all yours. Thank you. 744 00:43:59,589 --> 00:44:01,713 How much of this bread is fortified? 745 00:44:01,713 --> 00:44:04,522 No bread is fortified, in France, we don't fortify 746 00:44:04,522 --> 00:44:06,522 the flour with anything. 747 00:44:07,642 --> 00:44:09,932 But you have the same problems here with neural tube 748 00:44:09,932 --> 00:44:11,582 defects. 749 00:44:11,582 --> 00:44:15,574 Yes, sure, in fact, it is recommended for women who want 750 00:44:15,574 --> 00:44:18,963 to get pregnant or at the beginning of pregnancy to increase 751 00:44:18,963 --> 00:44:23,300 their intakes of vitamin B9 to prevent these birth defects. 752 00:44:23,300 --> 00:44:25,238 But why not just put it in the bread? 753 00:44:25,238 --> 00:44:29,444 No, the bread in France is quite a secret and traditional 754 00:44:29,444 --> 00:44:32,611 product, and no, it's not transformed. 755 00:44:34,154 --> 00:44:36,694 But do you add vitamins to any foods? 756 00:44:36,694 --> 00:44:39,745 Yes, there are fortifications of food with some vitamins 757 00:44:39,745 --> 00:44:42,160 or minerals but it's not mandatory, it's at the 758 00:44:42,160 --> 00:44:44,323 discretion of manufacturers. 759 00:44:44,323 --> 00:44:45,782 A lot of people around the world are worried about 760 00:44:45,782 --> 00:44:47,763 getting too few vitamins. 761 00:44:47,763 --> 00:44:49,521 Your concern is too many. 762 00:44:49,521 --> 00:44:53,562 Yeah, it depends on country such as France or Europe. 763 00:44:53,562 --> 00:44:57,156 You don't have problems of deficiency in general, you really 764 00:44:57,156 --> 00:45:01,361 have much more problem of excess, excess in the sugar, 765 00:45:01,361 --> 00:45:04,103 salt, and so on and maybe excess in vitamins if you take 766 00:45:04,103 --> 00:45:07,261 fortified foods, stable foods rich in vitamins, minerals 767 00:45:07,261 --> 00:45:09,320 and daily supplements. 768 00:45:09,320 --> 00:45:12,199 Maybe you can reach excessive intakes. 769 00:45:14,680 --> 00:45:16,971 The fortification of food by governments is the result 770 00:45:16,971 --> 00:45:21,122 of a careful assessment of potential risks versus benefits, 771 00:45:21,122 --> 00:45:24,643 but these days, industry can modify almost any food or 772 00:45:24,643 --> 00:45:29,204 drink with additional nutrients without the same scrutiny. 773 00:45:29,204 --> 00:45:32,163 In the United States, you can find a claim about the things 774 00:45:32,163 --> 00:45:35,338 that these products bring to you, 200 percent of which you 775 00:45:35,338 --> 00:45:39,838 need per day, and if the recommendation is 100 person, 776 00:45:41,350 --> 00:45:44,659 why are you taking 200 per person, and American people 777 00:45:44,659 --> 00:45:47,446 are used to such claims and they are used with this idea 778 00:45:47,446 --> 00:45:50,779 of too much of a thing is really better. 779 00:45:52,239 --> 00:45:56,165 In Europe, we really don't have this state of mind. 780 00:45:56,165 --> 00:45:58,564 Today, there is one vitamin in particular that's 781 00:45:58,564 --> 00:46:02,420 increasingly being added to our food, vitamin D. 782 00:46:02,420 --> 00:46:05,679 Low vitamin D has been linked to cancer, heart disease, 783 00:46:05,679 --> 00:46:10,540 dementia, it's been linked to over 100 different conditions. 784 00:46:10,540 --> 00:46:12,475 There are some who claim we're in a midst of a global 785 00:46:12,475 --> 00:46:15,280 vitamin D deficiency. 786 00:46:15,280 --> 00:46:17,392 So how do we decide whether we need extra vitamin D 787 00:46:17,392 --> 00:46:18,225 or not? 788 00:46:20,520 --> 00:46:22,802 (peaceful music) 789 00:46:36,335 --> 00:46:39,886 I've come to one of the coldest places on Earth 790 00:46:39,886 --> 00:46:44,469 to better understand the hottest vitamin on the planet. 791 00:46:49,217 --> 00:46:53,124 For centuries, a mysterious and horrible condition affected 792 00:46:53,124 --> 00:46:55,920 thousands of children all around the world. 793 00:46:55,920 --> 00:46:59,356 Their bones grew weak and broke easily and many were 794 00:46:59,356 --> 00:47:01,230 deformed, many died. 795 00:47:04,181 --> 00:47:07,446 They call the condition rickets, but no one knew 796 00:47:07,446 --> 00:47:08,696 what caused it. 797 00:47:10,336 --> 00:47:13,659 Oddly, here on the Norwegian coast, fewer cases were 798 00:47:13,659 --> 00:47:17,909 reported, so an important clue appeared to be fish. 799 00:47:19,574 --> 00:47:21,991 (airy music) 800 00:47:35,113 --> 00:47:38,620 The world's greatest cod harvest takes place here 801 00:47:38,620 --> 00:47:39,895 from January to April. 802 00:47:41,230 --> 00:47:44,106 (machinery whirring) 803 00:47:47,566 --> 00:47:50,672 Millions of tons are caught, their flesh 804 00:47:50,672 --> 00:47:52,589 helping feed the world. 805 00:47:55,978 --> 00:47:57,728 That is one big fish! 806 00:47:58,805 --> 00:48:01,807 But there's another benefit. 807 00:48:01,807 --> 00:48:06,224 A powerful traditional medicine called cod liver oil. 808 00:48:07,667 --> 00:48:10,398 Here in Norway, the stories of the healing powers of 809 00:48:10,398 --> 00:48:14,731 the cod liver oil go back more than 1000 years. 810 00:48:14,731 --> 00:48:17,975 It was a key part of the viking diet, prized for its 811 00:48:17,975 --> 00:48:20,830 strength giving utilities. 812 00:48:20,830 --> 00:48:24,163 The Norse called it the gold of the sea. 813 00:48:25,470 --> 00:48:28,145 This is a messy business. 814 00:48:28,145 --> 00:48:31,292 I don't know that I like it very much. 815 00:48:31,292 --> 00:48:35,420 So how do you know which one has a big liver? 816 00:48:36,177 --> 00:48:37,594 That's the liver. 817 00:48:39,483 --> 00:48:41,657 So the cod liver oil, do you think of it as a food 818 00:48:41,657 --> 00:48:43,740 or as a medicine? 819 00:48:55,920 --> 00:48:56,425 Not really sick. 820 00:48:57,282 --> 00:48:59,282 Does it taste like fish? 821 00:49:00,246 --> 00:49:02,163 Do you like the flavor? 822 00:49:07,193 --> 00:49:09,507 (laughing) 823 00:49:09,507 --> 00:49:11,924 (airy music) 824 00:49:17,548 --> 00:49:21,330 There are hundreds of thousands of heads and tails strung 825 00:49:21,330 --> 00:49:25,242 out on drying racks almost every village. 826 00:49:25,242 --> 00:49:29,582 And it's incredible to see the scale of the cod fishing here 827 00:49:29,582 --> 00:49:30,749 and the smell. 828 00:49:31,946 --> 00:49:35,869 The stench of cod blankets entire villages. 829 00:49:35,869 --> 00:49:39,810 The locals say it's the smell of money, but the value 830 00:49:39,810 --> 00:49:43,404 of cod and their livers goes far beyond money. 831 00:49:43,404 --> 00:49:45,321 It's also about health. 832 00:49:47,200 --> 00:49:49,783 (gulls crying) 833 00:49:52,767 --> 00:49:55,453 Professor Magritt Brustad is an expert in the links 834 00:49:55,453 --> 00:49:59,536 between food like cod and diseases, like rickets. 835 00:50:01,545 --> 00:50:06,249 Rickets was a huge problem in Norway some years ago. 836 00:50:06,249 --> 00:50:10,999 Rickets is a condition that is characterized by soft bone 837 00:50:13,380 --> 00:50:17,949 so it causes your bone and your skeleton be disformed 838 00:50:17,949 --> 00:50:20,427 and it's rather painful. 839 00:50:20,427 --> 00:50:22,504 And if this happens in childhood, 840 00:50:22,504 --> 00:50:23,819 it's permanent. 841 00:50:23,819 --> 00:50:27,136 Yeah, if it's not treated. 842 00:50:27,136 --> 00:50:30,122 I mean, this is just horrible. 843 00:50:30,122 --> 00:50:31,955 Yeah, a lot of pain. 844 00:50:34,947 --> 00:50:38,831 We knew many years ago that cod liver oil could cure 845 00:50:38,831 --> 00:50:41,498 rickets, but we didn't know why. 846 00:50:42,799 --> 00:50:46,248 Magritt and I have come to see how codfish is turned 847 00:50:46,248 --> 00:50:48,575 into cod liver oil. 848 00:50:48,575 --> 00:50:49,878 Welcome. Thank you! 849 00:50:49,878 --> 00:50:52,628 You are not seeing this before. 850 00:50:53,716 --> 00:50:56,958 It's a simple if revolting business. 851 00:50:56,958 --> 00:51:00,400 Cut out the fish livers, throw them into barrels, 852 00:51:00,400 --> 00:51:03,250 and let them decompose. 853 00:51:03,250 --> 00:51:07,260 The oil grows darker in the rotting process. 854 00:51:07,260 --> 00:51:12,100 Then skim off the oil from the surface and drink. 855 00:51:12,100 --> 00:51:13,834 You sure this is safe? 856 00:51:17,398 --> 00:51:19,981 Yeah, it's not bad. 857 00:51:22,704 --> 00:51:23,780 (all laughing) 858 00:51:23,780 --> 00:51:25,254 That was much better 859 00:51:25,254 --> 00:51:26,754 than I remember it as a child. 860 00:51:26,754 --> 00:51:27,587 Really? 861 00:51:28,653 --> 00:51:32,925 It's not nearly as bad as I was expecting. 862 00:51:32,925 --> 00:51:36,100 Cod liver oil was so successful in treating rickets 863 00:51:36,100 --> 00:51:37,957 that people across Europe began 864 00:51:37,957 --> 00:51:40,374 feeding it to their children. 865 00:51:41,264 --> 00:51:46,181 In the 1870s, it reached America, and mass marketing began. 866 00:51:50,210 --> 00:51:52,877 (vibrant music) 867 00:51:53,809 --> 00:51:57,392 But still, no one understood why it worked. 868 00:52:02,856 --> 00:52:06,441 In the early days, cod liver oil was mostly marketed 869 00:52:06,441 --> 00:52:11,441 as again, a kind of product that would help build flesh. 870 00:52:11,865 --> 00:52:15,520 In fact, this one product here of Scott's Emulsion, one of 871 00:52:15,520 --> 00:52:18,399 the biggest cod liver oil products. 872 00:52:18,399 --> 00:52:22,407 Scott started making this product in the 1870s. 873 00:52:22,407 --> 00:52:26,738 He really believed in advertising and he was able to make 874 00:52:26,738 --> 00:52:30,659 a fortune off of this particular product. 875 00:52:30,659 --> 00:52:32,842 You know, the important thing is if you're marketing this, 876 00:52:32,842 --> 00:52:36,755 you want people to take it as much as possible. 877 00:52:36,755 --> 00:52:39,836 By the late 1890s, the cod liver oil industry 878 00:52:39,836 --> 00:52:43,205 was booming, but the marketing ran decades ahead of 879 00:52:43,205 --> 00:52:44,205 the science. 880 00:52:45,683 --> 00:52:49,896 It wasn't until 1913 that biochemist Elmer McCullum 881 00:52:49,896 --> 00:52:52,752 and Marguerite Davis proved the existence of an essential 882 00:52:52,752 --> 00:52:55,272 nutrient in cod liver oil. 883 00:52:55,272 --> 00:52:58,450 They called it fat soluble A. 884 00:52:58,450 --> 00:53:00,628 A simply for the first vitamin. 885 00:53:01,516 --> 00:53:05,141 McCullum later identified another vitamin in cod liver oil, 886 00:53:05,141 --> 00:53:07,974 fat soluble D, the fourth vitamin. 887 00:53:09,951 --> 00:53:14,618 And McCullum proved it was vitamin D that cured rickets. 888 00:53:15,593 --> 00:53:18,620 So you have this new scientific knowledge coalescing with 889 00:53:18,620 --> 00:53:21,894 what is already kind of a market out there, so if you're 890 00:53:21,894 --> 00:53:24,863 marketing this stuff, I can't imagine anything better 891 00:53:24,863 --> 00:53:26,335 to come along. 892 00:53:26,335 --> 00:53:27,523 - [Derek] It's pretty incredible, right? 893 00:53:27,523 --> 00:53:30,476 It is pretty incredible. 894 00:53:30,476 --> 00:53:35,710 And there were hints of something else at play. 895 00:53:35,710 --> 00:53:38,285 In 1920, microbiologist Harriette Chick carried out an 896 00:53:38,285 --> 00:53:40,368 experiment with children. 897 00:53:41,947 --> 00:53:46,706 Half were given cod liver oil, the other half were not. 898 00:53:46,706 --> 00:53:48,783 As expected, the children given the oil 899 00:53:48,783 --> 00:53:52,844 didn't develop rickets, but then Dr. Chick noticed that 900 00:53:52,844 --> 00:53:56,678 children with rickets who spent time outside in the sun 901 00:53:56,678 --> 00:53:57,928 healed rapidly. 902 00:53:58,879 --> 00:54:02,323 She determined that cod liver oil and sunshine both 903 00:54:02,323 --> 00:54:03,490 cured rickets. 904 00:54:07,630 --> 00:54:09,230 And vitamin D is the link. 905 00:54:16,391 --> 00:54:19,970 How's that sunlight feeling? 906 00:54:19,970 --> 00:54:20,570 Oh, it's wonderful. 907 00:54:20,570 --> 00:54:21,837 Isn't it? 908 00:54:21,837 --> 00:54:25,400 So how does the sun deliver a vitamin? 909 00:54:25,934 --> 00:54:30,192 When sunlight hits our skin, something remarkable happens. 910 00:54:30,192 --> 00:54:34,747 Just under the surface lies a type of cholesterol. 911 00:54:34,747 --> 00:54:37,678 When the sun's ultraviolet rays hit this molecule, 912 00:54:37,678 --> 00:54:41,345 it transforms, becoming a form of vitamin D. 913 00:54:42,974 --> 00:54:47,652 This is the same molecule found in cod liver oil. 914 00:54:47,652 --> 00:54:50,638 It then travels to the liver, where it's converted into 915 00:54:50,638 --> 00:54:54,952 the form that doctors measure in our blood. 916 00:54:54,952 --> 00:54:58,869 This is then activated by the kidneys, and now, 917 00:55:00,621 --> 00:55:05,500 it's ready to help absorb calcium, building strong, healthy, 918 00:55:05,500 --> 00:55:06,633 rickets free bones. 919 00:55:07,827 --> 00:55:10,495 Think that's about enough sun for one day. 920 00:55:10,495 --> 00:55:12,912 (airy music) 921 00:55:19,660 --> 00:55:22,729 But here in the far north, during the dark winter months, 922 00:55:22,729 --> 00:55:25,900 there's a distinct lack of sunshine, so to get enough 923 00:55:25,900 --> 00:55:30,387 vitamin D, over generations, people have devised rather 924 00:55:30,387 --> 00:55:32,970 remarkable meals to compensate. 925 00:55:34,970 --> 00:55:35,264 This is cod. 926 00:55:36,453 --> 00:55:40,748 And this is cod eggs, and this is the boiled liver. 927 00:55:40,748 --> 00:55:43,688 It's fresh cod liver oil together with onion and pepper 928 00:55:43,688 --> 00:55:45,260 and salt. 929 00:55:45,260 --> 00:55:49,141 And this is potatoes, Norwegians always have potato. 930 00:55:49,141 --> 00:55:51,928 Ahh, very good. 931 00:55:51,928 --> 00:55:54,760 This is the traditional (foreign language), 932 00:55:54,760 --> 00:55:57,400 packed with vitamin D. 933 00:55:57,400 --> 00:56:00,343 So one meal of this will give you 16 out of 20 934 00:56:00,343 --> 00:56:05,630 daily doses of the recommended amount of vitamin D. 935 00:56:05,630 --> 00:56:08,175 This has kind of saved our vitamin D health 936 00:56:08,175 --> 00:56:10,525 in the north during the dark season. 937 00:56:10,525 --> 00:56:13,596 But not everyone likes oily fish, let alone 938 00:56:13,596 --> 00:56:16,960 fish livers and cod liver oil. 939 00:56:17,386 --> 00:56:21,523 So scientists invented something far more palatable. 940 00:56:21,523 --> 00:56:25,231 So the first really important vitamin pill is this 941 00:56:25,231 --> 00:56:30,231 Osdogal, and this was developed actually by Casimir Funk. 942 00:56:30,662 --> 00:56:34,333 We've solved a big problem that messy, nauseating oil 943 00:56:34,333 --> 00:56:38,861 is now a nice little pill in (mumbles) coated. 944 00:56:38,861 --> 00:56:41,686 So cod liver oil really started this whole vitamin 945 00:56:41,686 --> 00:56:43,126 explosion? 946 00:56:43,126 --> 00:56:46,822 Yes, cod liver oil really is the beginning of it. 947 00:56:46,822 --> 00:56:49,405 (bright music) 948 00:56:50,299 --> 00:56:52,729 With the new pills readily available, the era 949 00:56:52,729 --> 00:56:57,920 of cod as a key source of vitamin D was ended, and soon, 950 00:56:57,920 --> 00:57:00,920 the vast majority of vitamin D would be created in an 951 00:57:00,920 --> 00:57:05,920 utterly different manner from an utterly different beast. 952 00:57:05,415 --> 00:57:08,165 (sheep bleating) 953 00:57:09,640 --> 00:57:13,530 Today, most of the world's vitamin D pills are created 954 00:57:13,530 --> 00:57:15,553 from the greasy wool of sheep. 955 00:57:16,838 --> 00:57:18,838 Mostly Australian sheep. 956 00:57:20,561 --> 00:57:23,700 (clippers buzzing) 957 00:57:23,700 --> 00:57:27,450 So how do you turn sheep wool into a vitamin? 958 00:57:28,996 --> 00:57:30,663 Let's give it a try. 959 00:57:33,175 --> 00:57:36,924 Well, the wool is coated in a type of grease or lanolin, 960 00:57:36,924 --> 00:57:40,394 it's the stuff that makes your hands feel soft. 961 00:57:40,394 --> 00:57:42,870 It's a mixture of fatty acids produced by the sheep's 962 00:57:42,870 --> 00:57:47,787 oil glands, and this lanolin is the key to making synthetic 963 00:57:48,921 --> 00:57:49,754 vitamin D. 964 00:57:51,347 --> 00:57:54,750 (sheep bleating) 965 00:57:54,750 --> 00:57:56,917 Here's how it can be done. 966 00:58:00,123 --> 00:58:02,981 The lanolin is separated from the wool by boiling in 967 00:58:02,981 --> 00:58:04,981 hot water and detergent. 968 00:58:05,981 --> 00:58:09,993 Around 15 percent of the lanolin is a form of cholesterol, 969 00:58:09,993 --> 00:58:12,993 like the cholesterol under our skin. 970 00:58:14,760 --> 00:58:18,529 This is a extracted and oxidized to produce a new compound 971 00:58:18,529 --> 00:58:21,736 which is then irradiated with ultraviolet light, 972 00:58:21,736 --> 00:58:25,569 transforming it into a precursor of vitamin D. 973 00:58:27,131 --> 00:58:30,425 This chemical process mimics the biological process 974 00:58:30,425 --> 00:58:33,175 of the sunlight hitting our skin. 975 00:58:34,630 --> 00:58:36,898 Several more steps create the end product, 976 00:58:36,898 --> 00:58:38,565 synthetic vitamin D. 977 00:58:43,269 --> 00:58:46,502 And of course, it's not done like this, but on an 978 00:58:46,502 --> 00:58:49,200 industrial scale in factories. 979 00:58:49,963 --> 00:58:52,713 (peaceful music) 980 00:58:55,728 --> 00:58:57,684 Chemists from the University of Melbourne calculated 981 00:58:57,684 --> 00:59:01,486 that you can make a lot of money from a sheep's fleece. 982 00:59:01,486 --> 00:59:04,599 Online, vitamin D3 can seel for about 50 Australian 983 00:59:04,599 --> 00:59:08,893 dollars per gram, but packaged in pill form, it can sell 984 00:59:08,893 --> 00:59:11,643 for around 3700 dollars per gram. 985 00:59:13,523 --> 00:59:17,606 This makes vitamin D far more valuable than gold. 986 00:59:20,240 --> 00:59:23,157 But the million dollar question is should we be taking 987 00:59:23,157 --> 00:59:24,490 vitamin D pills? 988 00:59:36,130 --> 00:59:38,513 (tense music) 989 00:59:41,566 --> 00:59:45,837 Today, most of us spend large parts of our days indoors, 990 00:59:45,837 --> 00:59:49,535 with limited exposure to direct sunlight. 991 00:59:49,535 --> 00:59:52,438 So do we need more vitamin D? 992 00:59:52,438 --> 00:59:55,105 Should we be taking supplements? 993 00:59:56,510 --> 00:59:59,240 Dr. Rachel Neale is part of a global investigation 994 00:59:59,240 --> 01:00:00,823 trying to find out. 995 01:00:02,240 --> 01:00:05,850 Vitamin D's not just a vitamin, vitamin D is a hormone 996 01:00:05,850 --> 01:00:08,320 that has a range of incredibly powerful effects 997 01:00:08,320 --> 01:00:11,590 on the cells in our body that could determine whether or not 998 01:00:11,590 --> 01:00:14,789 that cell starts to divide uncontrollably and become 999 01:00:14,789 --> 01:00:17,471 a cancer for example or whether or not that cell gets 1000 01:00:17,471 --> 01:00:19,804 a mutation and kills itself. 1001 01:00:20,974 --> 01:00:23,918 So it's this incredibly powerful molecule that we need 1002 01:00:23,918 --> 01:00:27,340 to understand a lot more about before we just recommend 1003 01:00:27,340 --> 01:00:30,673 that everybody should take a supplement. 1004 01:00:33,627 --> 01:00:35,798 Rachel leads one of the world's largest 1005 01:00:35,798 --> 01:00:39,159 clinical trials of high dose vitamin D. 1006 01:00:39,159 --> 01:00:44,159 21 thousand people are taking a vitamin D pill or a placebo, 1007 01:00:44,168 --> 01:00:46,585 a sugar pill, for five years. 1008 01:00:47,543 --> 01:00:50,402 They're trying to see if taking vitamin D supplements 1009 01:00:50,402 --> 01:00:54,235 reduces the risk of cancer and other diseases. 1010 01:00:55,510 --> 01:00:59,183 I think the general public have a perception that 1011 01:00:59,183 --> 01:01:02,894 vitamin D is proven to be beneficial for a whole range 1012 01:01:02,894 --> 01:01:04,956 of different health outcomes, like cancer and 1013 01:01:04,956 --> 01:01:07,407 cardiovascular disease and the reality is that we know 1014 01:01:07,407 --> 01:01:10,831 vitamin D's incredibly important for our bones, but beyond 1015 01:01:10,831 --> 01:01:13,331 that, we don't yet have proof. 1016 01:01:14,176 --> 01:01:16,740 So why all the uncertainty? 1017 01:01:16,740 --> 01:01:21,153 Well first, there's debate around how much we actually need. 1018 01:01:21,153 --> 01:01:24,638 Vitamin D is measured in our blood in units generally 1019 01:01:24,638 --> 01:01:26,888 called nanomoles per liter. 1020 01:01:27,878 --> 01:01:32,309 Experts agree that below 25 is considered deficient, 1021 01:01:32,309 --> 01:01:35,251 but knowing what levels are sufficient is trickier. 1022 01:01:35,251 --> 01:01:37,232 A level over 50 is generally thought to be enough 1023 01:01:37,232 --> 01:01:41,649 for good bone health for most people but others argue 1024 01:01:44,271 --> 01:01:46,688 for 75 or 100 or even higher. 1025 01:01:49,970 --> 01:01:52,557 It's worth noting that the US used a different measure, 1026 01:01:52,557 --> 01:01:56,646 nanograms per milliliter and like metric versus imperial, 1027 01:01:56,646 --> 01:01:59,896 this can cause international confusion. 1028 01:02:01,199 --> 01:02:05,426 So we don't yet have a single number that is accepted 1029 01:02:05,426 --> 01:02:09,560 by all organizations and all scientists and all doctors 1030 01:02:09,560 --> 01:02:10,473 around the world. 1031 01:02:11,737 --> 01:02:16,319 There's also controversy around blood testing, 1032 01:02:16,319 --> 01:02:17,846 with studies showing different labs can get very different 1033 01:02:17,846 --> 01:02:21,887 results, and although we know taking supplements increases 1034 01:02:21,887 --> 01:02:25,759 the levels of vitamin D in our blood, we don't yet know 1035 01:02:25,759 --> 01:02:28,419 if this improves our health. 1036 01:02:28,419 --> 01:02:31,200 (lively music) 1037 01:02:44,540 --> 01:02:47,960 So we don't know what vitamin D does yet. 1038 01:02:47,960 --> 01:02:50,540 We've got hints about what vitamin D might do but what 1039 01:02:50,540 --> 01:02:51,955 we don't know is- 1040 01:02:51,955 --> 01:02:53,901 Different kinds of studies are revealing 1041 01:02:53,901 --> 01:02:56,616 different kinds of clues. 1042 01:02:56,616 --> 01:02:58,993 These people are getting a fair amount of vitamin D. 1043 01:02:58,993 --> 01:03:00,388 They are. 1044 01:03:00,388 --> 01:03:02,463 Vitamin D studies are often 1045 01:03:02,463 --> 01:03:06,790 observational, meaning they observe the world as it is. 1046 01:03:06,790 --> 01:03:09,707 For example, people with cancer often have low levels 1047 01:03:09,707 --> 01:03:11,810 of vitamin D in their blood. 1048 01:03:11,810 --> 01:03:15,681 The link is clear and potentially important. 1049 01:03:15,681 --> 01:03:19,255 But it doesn't tell us if low vitamin D caused the cancer 1050 01:03:19,255 --> 01:03:22,422 or if the cancer caused low vitamin D. 1051 01:03:25,489 --> 01:03:28,885 To work it out, we need to do the kind of study pioneered 1052 01:03:28,885 --> 01:03:31,135 by James Lind back in 1747. 1053 01:03:32,412 --> 01:03:34,829 The randomized control trial. 1054 01:03:35,857 --> 01:03:40,535 Take a group of people, divide randomly in two, give 1055 01:03:40,535 --> 01:03:45,134 vitamin D to one group and a placebo to the other, then, if 1056 01:03:45,134 --> 01:03:47,874 you see a difference between these groups, you know it was 1057 01:03:47,874 --> 01:03:52,541 caused by vitamin D, and better still, do this at scale. 1058 01:03:53,896 --> 01:03:56,334 The more people in your study, the more confident you can 1059 01:03:56,334 --> 01:03:57,834 be of the results. 1060 01:03:59,495 --> 01:04:02,245 Rachel's results are due in 2021. 1061 01:04:06,657 --> 01:04:09,528 It's very exciting but currently the jury really is out 1062 01:04:09,528 --> 01:04:13,861 on what we should be recommending to the population. 1063 01:04:19,920 --> 01:04:23,220 Despite the uncertainty, in 2016, UK 1064 01:04:23,220 --> 01:04:25,896 scientists recommended an increase in the recommended 1065 01:04:25,896 --> 01:04:28,630 daily amount of vitamin D. 1066 01:04:29,736 --> 01:04:31,403 Not everyone agrees. 1067 01:04:32,945 --> 01:04:35,893 One high profile champion of vitamin D has since changed 1068 01:04:35,893 --> 01:04:36,726 his mind. 1069 01:04:37,878 --> 01:04:40,628 Geneticist professor Tim Spector. 1070 01:04:41,646 --> 01:04:44,865 I've studied vitamin D a lot in the last 15 years 1071 01:04:44,865 --> 01:04:46,755 and we were the first group to show 1072 01:04:46,755 --> 01:04:49,572 that the levels in individuals is 1073 01:04:49,572 --> 01:04:53,383 actually partly controlled by your genes so we always assume 1074 01:04:53,383 --> 01:04:56,864 it's purely how much sunshine you get or how much oily fish 1075 01:04:56,864 --> 01:05:00,917 you're eating but in fact, about 50 percent of the levels 1076 01:05:00,917 --> 01:05:04,398 vary just because the genes you've got and so everyone 1077 01:05:04,398 --> 01:05:08,697 has a different normal level of their vitamins and that is 1078 01:05:08,697 --> 01:05:11,144 generally holding true for all the vitamins we've been able 1079 01:05:11,144 --> 01:05:15,380 to test so far so our idea of normal should actually be very 1080 01:05:15,380 --> 01:05:18,554 person specific so you might have a normal level that's 1081 01:05:18,554 --> 01:05:21,988 three times higher than mine and we don't really know what 1082 01:05:21,988 --> 01:05:24,738 is the good level and what's low. 1083 01:05:25,737 --> 01:05:28,710 I think the public (mumbles) realize there is a controversy 1084 01:05:28,710 --> 01:05:31,742 here and all these amounts of vitamins are important for us, 1085 01:05:31,742 --> 01:05:33,819 but let's wait for the proper trials before we make a 1086 01:05:33,819 --> 01:05:36,993 decision rather than the default being the artificial 1087 01:05:36,993 --> 01:05:40,325 chemical first, worry about it later. 1088 01:05:40,325 --> 01:05:42,970 Let's get our facts right, make sure we're not doing 1089 01:05:42,970 --> 01:05:44,232 something harmful first. 1090 01:05:44,232 --> 01:05:46,118 There's no doubt that we need to clinically manage 1091 01:05:46,118 --> 01:05:49,285 people who have vitamin deficiency, it's important we 1092 01:05:49,285 --> 01:05:53,109 recognize that vitamin D deficiency is a real thing, but we 1093 01:05:53,109 --> 01:05:56,640 don't yet have the evidence to be able to say to the general 1094 01:05:56,640 --> 01:06:01,640 population taking a vitamin D supplement is a good thing. 1095 01:06:02,420 --> 01:06:05,359 So should we just get more sun? 1096 01:06:05,359 --> 01:06:08,149 What about the risk of skin cancer? 1097 01:06:08,149 --> 01:06:13,149 Well, like everything around vitamin D, it's complicated. 1098 01:06:13,291 --> 01:06:15,896 In sunny climates, most people get enough from short bursts 1099 01:06:15,896 --> 01:06:19,201 of sunshine a few times a week. 1100 01:06:19,201 --> 01:06:22,824 Although of course sunscreen should always be used. 1101 01:06:22,824 --> 01:06:26,756 And in less sunny places, more deliberate sun exposure 1102 01:06:26,756 --> 01:06:31,756 may be needed, or your doctor may recommend supplementation. 1103 01:06:33,469 --> 01:06:38,469 Vitamin D is powerful, no question, but can we get too much 1104 01:06:38,520 --> 01:06:40,436 of a good thing? 1105 01:06:40,436 --> 01:06:42,936 (tense music) 1106 01:06:53,740 --> 01:06:58,367 They were born at 9:45, so he came out first and she was 1107 01:06:58,367 --> 01:07:02,187 a minute later, so they're just a minute apart. 1108 01:07:02,187 --> 01:07:04,634 When Becky Jackson gave birth to twins Joe 1109 01:07:04,634 --> 01:07:07,358 and Elizabeth, she was thrilled. 1110 01:07:07,358 --> 01:07:09,591 So that's three months and you know, 1111 01:07:09,591 --> 01:07:12,690 Joe was such a little chunkalunk at first. 1112 01:07:12,690 --> 01:07:13,890 But when she noticed her five month old 1113 01:07:13,890 --> 01:07:17,397 daughter wasn't growing as quickly as her twin brother, 1114 01:07:17,397 --> 01:07:19,412 Becky began to worry. 1115 01:07:19,412 --> 01:07:22,194 And so here's five months and you can see her eyes look 1116 01:07:22,194 --> 01:07:26,349 a little baggy and sunken and her face just looks 1117 01:07:26,349 --> 01:07:28,970 a little strange. 1118 01:07:28,970 --> 01:07:32,142 These pictures, nothing was alarming really until this one. 1119 01:07:32,142 --> 01:07:35,740 Suddenly, things took a turn for the worse. 1120 01:07:35,740 --> 01:07:38,848 Elizabeth wasn't gaining weight and she just wouldn't eat. 1121 01:07:38,848 --> 01:07:41,694 I noticed one day when I was changing her diaper that 1122 01:07:41,694 --> 01:07:44,179 her stomach looked sunken, I could see the bottom of her 1123 01:07:44,179 --> 01:07:48,929 ribcage and her skin looked and felt strange, almost like 1124 01:07:49,781 --> 01:07:51,436 pizza dough. 1125 01:07:51,436 --> 01:07:54,480 Becky took her to the doctor for blood tests. 1126 01:07:54,480 --> 01:07:56,858 The next day, the doctor called. 1127 01:07:56,858 --> 01:08:00,803 She said "You have to go to children's hospital right now, 1128 01:08:00,803 --> 01:08:05,940 "everything is all over the place, things that are low 1129 01:08:05,940 --> 01:08:07,568 "should be high, things that are high should be low, 1130 01:08:07,568 --> 01:08:10,644 "nothing is where it should be." 1131 01:08:10,644 --> 01:08:13,144 (tense music) 1132 01:08:18,478 --> 01:08:23,203 I was freaking out, I was panicked, I didn't know what any 1133 01:08:23,203 --> 01:08:28,360 of it meant for a couple of days which was the scary part. 1134 01:08:28,961 --> 01:08:31,667 The tests revealed that Elizabeth had toxic 1135 01:08:31,667 --> 01:08:35,509 levels of vitamin D and this was causing dangerously high 1136 01:08:35,509 --> 01:08:38,920 levels of calcium in her blood. 1137 01:08:39,493 --> 01:08:43,586 I have never seen a case of vitamin D toxicity until 1138 01:08:43,586 --> 01:08:44,919 I saw Elizabeth. 1139 01:08:45,986 --> 01:08:49,554 She's only five or six months old and pretty much a baby's 1140 01:08:49,554 --> 01:08:52,759 diet is mostly formula, so we had to do a little 1141 01:08:52,759 --> 01:08:57,759 investigation why or where could she have gotten that. 1142 01:08:57,816 --> 01:09:01,378 When they first said the words "hypercalcemia" to me, 1143 01:09:01,378 --> 01:09:05,130 then I did what every parent does and I googled and I got 1144 01:09:05,130 --> 01:09:08,980 online and I found out everything I could about it and then 1145 01:09:08,980 --> 01:09:11,907 I started to see a recurring theme of high doses of 1146 01:09:11,907 --> 01:09:14,852 vitamin D, vitamin D overdose. 1147 01:09:14,852 --> 01:09:16,602 And I knew instantly. 1148 01:09:19,820 --> 01:09:21,978 So you start with powdered goat's milk and you put in 1149 01:09:21,978 --> 01:09:23,749 eight scoops. 1150 01:09:23,749 --> 01:09:25,444 Becky didn't have enough breast milk for 1151 01:09:25,444 --> 01:09:28,463 both twins, so she decided to keep Joe on breast milk 1152 01:09:28,463 --> 01:09:31,610 while Elizabeth received a mix of breast milk and homemade 1153 01:09:31,610 --> 01:09:33,261 formula. 1154 01:09:33,261 --> 01:09:36,428 Vitamin C, vitamin E, coral calcium. 1155 01:09:39,490 --> 01:09:41,729 This is cod liver oil. 1156 01:09:41,729 --> 01:09:44,248 It was an organic recipe of goat milk 1157 01:09:44,248 --> 01:09:47,364 and coconut milk from a local health store. 1158 01:09:47,364 --> 01:09:51,427 And this was the soy lecithin which is a thickener. 1159 01:09:51,427 --> 01:09:53,834 And wanting to do the best for her baby, 1160 01:09:53,834 --> 01:09:57,401 Becky decided to add a little something extra to the mix. 1161 01:09:57,401 --> 01:10:00,530 And then lastly is the vitamin D. 1162 01:10:00,530 --> 01:10:01,795 How much do you put in? 1163 01:10:01,795 --> 01:10:04,962 Well, the recipe calls for one drop. 1164 01:10:07,149 --> 01:10:08,463 One drop. 1165 01:10:08,463 --> 01:10:09,296 That's all that-- that's it. 1166 01:10:09,296 --> 01:10:12,530 Put in. Which seems trivial 1167 01:10:12,530 --> 01:10:15,401 at best, that's just silliness, that's not gonna do anything 1168 01:10:15,401 --> 01:10:19,401 for anybody, so I would do the whole dropperful. 1169 01:10:22,483 --> 01:10:26,111 One ML or full dropper, like most infant droppers, 1170 01:10:26,111 --> 01:10:29,280 would contain about 20 to 30 drops. 1171 01:10:31,658 --> 01:10:34,603 If there's too much vitamin D, then you will reabsorb 1172 01:10:34,603 --> 01:10:39,210 a lot of the calcium, then it causes some of the symptoms 1173 01:10:39,210 --> 01:10:43,220 would be increased urination, lack of appetite, both of 1174 01:10:43,220 --> 01:10:45,889 which could lead to dehydration. 1175 01:10:45,889 --> 01:10:49,396 If this condition persisted without any treatment 1176 01:10:49,396 --> 01:10:53,353 or intervention, this could ultimately lead to Elizabeth 1177 01:10:53,353 --> 01:10:55,186 having kidney failure. 1178 01:11:00,783 --> 01:11:03,463 And then this was in the actual hospital with the feeding 1179 01:11:03,463 --> 01:11:07,177 tube but she's rounded out, she's plumped up and had 1180 01:11:07,177 --> 01:11:10,231 started to look normal again. 1181 01:11:10,231 --> 01:11:12,540 It took 10 days in hospital to stabilize 1182 01:11:12,540 --> 01:11:13,457 her levels. 1183 01:11:14,719 --> 01:11:16,469 I felt very guilty. 1184 01:11:17,335 --> 01:11:21,982 I did this, this is something that I did and I knew that I 1185 01:11:21,982 --> 01:11:25,885 was giving her too much when I was doing it but I thought 1186 01:11:25,885 --> 01:11:27,270 "What harm could there be? 1187 01:11:27,270 --> 01:11:29,634 "It's just a vitamin, it's like vitamin C, you get rid 1188 01:11:29,634 --> 01:11:34,510 "of what you don't need, how could it be a big deal?" 1189 01:11:35,199 --> 01:11:38,850 I was trying to be a good mom, I was trying to go above 1190 01:11:38,850 --> 01:11:42,418 and beyond in a very easy, every day way that seemed 1191 01:11:43,612 --> 01:11:44,612 so harmless. 1192 01:11:49,633 --> 01:11:53,940 I think people have underestimated the power of these 1193 01:11:53,940 --> 01:11:55,940 vitamins with vitamin D. 1194 01:11:57,814 --> 01:12:02,632 You know, little mistakes can mean a lot if it's tenfold, 1195 01:12:02,632 --> 01:12:06,299 hundredfold, that can really spell disaster. 1196 01:12:08,574 --> 01:12:11,800 Luckily, Elizabeth is now fine. 1197 01:12:11,800 --> 01:12:12,913 Her levels are normal. 1198 01:12:14,892 --> 01:12:18,329 It's difficult to overdose on vitamins in food, but easy 1199 01:12:18,329 --> 01:12:21,747 to do with manmade vitamins as they can be consumed in such 1200 01:12:21,747 --> 01:12:26,900 large quantities, and fat soluble vitamins like D can 1201 01:12:26,900 --> 01:12:30,257 accumulate in body fat, reaching dangerous levels. 1202 01:12:36,396 --> 01:12:39,560 Becky Jackson and her family are not alone. 1203 01:12:39,560 --> 01:12:42,860 In 2015, the US Poison Center reported over 3000 calls 1204 01:12:42,860 --> 01:12:45,384 concerning children under six who had taken too much 1205 01:12:45,384 --> 01:12:46,217 vitamin D. 1206 01:12:48,692 --> 01:12:51,192 (tense music) 1207 01:12:56,153 --> 01:12:58,716 Throughout the world, the potential risks of dietary 1208 01:12:58,716 --> 01:13:02,439 supplements are being studied carefully. 1209 01:13:02,439 --> 01:13:05,655 There's no question now that we have the data after 1210 01:13:05,655 --> 01:13:09,818 decades of study, really, that the supplements are not 1211 01:13:09,818 --> 01:13:11,206 risk free. 1212 01:13:11,206 --> 01:13:13,440 And in America, supplements send tens of thousands of 1213 01:13:13,440 --> 01:13:17,722 consumers to emergency departments every year and thousands 1214 01:13:17,722 --> 01:13:20,942 of hospitalizations every year are due to serious side 1215 01:13:20,942 --> 01:13:23,445 effects of supplements. 1216 01:13:23,445 --> 01:13:25,224 Tonight, Walgreens and Target have pulled 1217 01:13:25,224 --> 01:13:27,900 the products nationwide. 1218 01:13:27,900 --> 01:13:28,465 GNC did the same in-- 1219 01:13:28,465 --> 01:13:31,378 In 2015, dietary supplements were pulled off 1220 01:13:31,378 --> 01:13:35,775 the shelves of four major pharmacy chains in New York. 1221 01:13:35,775 --> 01:13:38,174 Most of the supplements tested didn't contain the 1222 01:13:38,174 --> 01:13:41,687 materials listed on the label and many contained 1223 01:13:41,687 --> 01:13:42,770 contaminants. 1224 01:13:44,497 --> 01:13:47,364 One of the serious safety concerns has been serious 1225 01:13:47,364 --> 01:13:50,558 deficits in the manufacturing process. 1226 01:13:50,558 --> 01:13:53,950 For example, there have been multi-vitamins in which the 1227 01:13:53,950 --> 01:13:57,457 amount of a mineral has been 100 times greater than what 1228 01:13:57,457 --> 01:14:01,448 it should be, leading to serious health defects. 1229 01:14:01,448 --> 01:14:04,615 In other multi-vitamins, there has been drugs that weren't 1230 01:14:04,615 --> 01:14:08,281 supposed to be in there at all, such as anabolic steroids, 1231 01:14:08,281 --> 01:14:10,722 these are steroids that weightlifters might clandestinely 1232 01:14:10,722 --> 01:14:14,522 use to get stronger have been found in multi-vitamins 1233 01:14:14,522 --> 01:14:19,420 at such levels that people taking it became sick. 1234 01:14:19,420 --> 01:14:22,139 Specific risks are appearing around specific 1235 01:14:22,139 --> 01:14:24,222 vitamins, like vitamin D. 1236 01:14:25,940 --> 01:14:28,542 We're seeing levels of five times, ten times normal 1237 01:14:28,542 --> 01:14:31,562 in the blood of my patients when I see them with 1238 01:14:31,562 --> 01:14:35,622 osteopetrosis and studies are now showing these people 1239 01:14:35,622 --> 01:14:38,644 are now actually more prone to fractures and more prone 1240 01:14:38,644 --> 01:14:43,226 to falling down and all the evidence is building up that we 1241 01:14:43,226 --> 01:14:47,890 actually have a fairly narrow range of where these 1242 01:14:47,890 --> 01:14:49,570 vitamins work. 1243 01:14:50,632 --> 01:14:53,369 Every vitamin has a toxic level and some of them are 1244 01:14:53,369 --> 01:14:55,591 actually not that much higher than just the normal 1245 01:14:55,591 --> 01:14:57,546 nutritional amount. 1246 01:14:57,546 --> 01:15:01,280 I see patients all the time who have vitamin B six levels 1247 01:15:01,280 --> 01:15:03,890 in the toxic range and it can cause nerve damage 1248 01:15:03,890 --> 01:15:04,890 for example. 1249 01:15:06,646 --> 01:15:09,373 In the 1990s, studies testing a form of 1250 01:15:09,373 --> 01:15:13,344 vitamin A were halted when it became clear that participants 1251 01:15:13,344 --> 01:15:16,261 were at an increased risk of dying. 1252 01:15:17,913 --> 01:15:21,552 That really shocked I think almost everyone. 1253 01:15:21,552 --> 01:15:23,807 We need to look at the type of supplement, we need to look 1254 01:15:23,807 --> 01:15:26,314 at the amount of supplement, we need to look at what's 1255 01:15:26,314 --> 01:15:30,490 being given to and it does seem that there are some places 1256 01:15:30,490 --> 01:15:33,565 where vitamin supplements can definitely provide benefit, 1257 01:15:33,565 --> 01:15:36,120 there are a number of places where they can provide 1258 01:15:36,120 --> 01:15:39,890 some harm and there are a lot of places where they're still 1259 01:15:39,890 --> 01:15:42,183 not sure what the outcomes will be. 1260 01:15:42,183 --> 01:15:46,255 So the big picture is that these products are not 1261 01:15:46,255 --> 01:15:47,997 entirely safe. 1262 01:15:47,997 --> 01:15:49,909 It's not that they're gonna harm everyone who's gonna take 1263 01:15:49,909 --> 01:15:51,436 them, certainly not. 1264 01:15:51,436 --> 01:15:52,997 The majority of people aren't gonna experience any 1265 01:15:52,997 --> 01:15:54,731 adverse effects. 1266 01:15:54,731 --> 01:15:56,730 But my concern is this. 1267 01:15:56,730 --> 01:16:01,730 If these products are offering none to almost no benefit 1268 01:16:02,154 --> 01:16:07,154 to a healthy consumer, but posing a small risk of harm, 1269 01:16:07,259 --> 01:16:10,482 why should we be recommending them and why should consumers 1270 01:16:10,482 --> 01:16:11,649 be using them? 1271 01:16:14,633 --> 01:16:16,342 Now there's no questions that medicines can have 1272 01:16:16,342 --> 01:16:18,547 dangerous side effects and complications. 1273 01:16:18,547 --> 01:16:20,874 But they're clearly stated on the label and doctors know 1274 01:16:20,874 --> 01:16:22,161 to look out for them. 1275 01:16:22,161 --> 01:16:23,601 It's a known risk. 1276 01:16:23,601 --> 01:16:26,123 The issue with vitamins and dietary supplements is that 1277 01:16:26,123 --> 01:16:28,789 they're perceived to be risk free. 1278 01:16:28,789 --> 01:16:31,619 Yet there can be complications, there can be side effects, 1279 01:16:31,619 --> 01:16:34,630 and there can be bad products. 1280 01:16:34,630 --> 01:16:36,220 It's not a no risk proposition. 1281 01:16:36,220 --> 01:16:38,803 (lively music) 1282 01:16:41,428 --> 01:16:44,778 Yet, in the US, there's no legal requirement for products 1283 01:16:44,778 --> 01:16:47,645 to be tested for safety or effectiveness before 1284 01:16:47,645 --> 01:16:48,978 they go on sale. 1285 01:16:50,411 --> 01:16:53,220 In the US and in many countries, the laws are lax to the 1286 01:16:53,220 --> 01:16:55,120 point where you can basically put any combination of 1287 01:16:55,120 --> 01:16:58,486 vitamins and minerals in a pill, call it anything you want 1288 01:16:58,486 --> 01:17:01,545 and make pseudo-health claims for it. 1289 01:17:01,545 --> 01:17:03,378 So it's the wild west. 1290 01:17:05,509 --> 01:17:08,930 Clearly, there is a huge problem in supplement use that's 1291 01:17:08,930 --> 01:17:11,422 not regulated, there are things there 1292 01:17:11,422 --> 01:17:12,694 that shouldn't be there, 1293 01:17:12,694 --> 01:17:16,161 there are things that should be there that aren't there. 1294 01:17:16,161 --> 01:17:19,218 It is sort of the wild west. 1295 01:17:19,218 --> 01:17:21,925 To understand how this could happen, we need 1296 01:17:21,925 --> 01:17:23,800 to look back. 1297 01:17:26,651 --> 01:17:29,156 To see how the line between food 1298 01:17:29,156 --> 01:17:31,489 and medicine became blurred. 1299 01:17:33,283 --> 01:17:38,283 ♪ Well, let's talk about the US government of 1938 ♪ 1300 01:17:40,132 --> 01:17:45,132 ♪ The burgeoning new industry, they didn't regulate ♪ 1301 01:17:46,668 --> 01:17:48,108 ♪ Said it makes no sense ♪ 1302 01:17:48,108 --> 01:17:53,108 ♪ They're just dispensing nutrients my dear ♪ 1303 01:17:53,592 --> 01:17:58,592 ♪ And if we pop that bottle top, we know what we would hear ♪ 1304 01:17:58,773 --> 01:18:03,773 ♪ I am not a medicine, I am not a drug ♪ 1305 01:18:04,848 --> 01:18:08,811 ♪ Dude, I'm food, so don't intrude, it's rude ♪ 1306 01:18:08,811 --> 01:18:12,256 ♪ To pull my plug ♪ 1307 01:18:12,256 --> 01:18:17,256 ♪ I wanna be a mystery, don't peer inside the pill ♪ 1308 01:18:19,253 --> 01:18:23,890 ♪ And if I'm not a medicine ♪ 1309 01:18:23,890 --> 01:18:26,506 ♪ Perhaps you never will ♪ 1310 01:18:28,561 --> 01:18:31,736 In 1938, a new US law requires all pharmaceutical 1311 01:18:31,736 --> 01:18:35,184 drugs to be tested for safety, but vitamins escaped 1312 01:18:35,184 --> 01:18:37,605 this regulation, opening the door for the industry 1313 01:18:37,605 --> 01:18:38,981 to expand. 1314 01:18:38,981 --> 01:18:41,824 And by the 1970s, the industry is booming. 1315 01:18:41,824 --> 01:18:44,716 The FDA, concerned about high dose vitamins, tries to 1316 01:18:44,716 --> 01:18:47,543 tighten the rules, but fails. 1317 01:18:47,543 --> 01:18:49,412 They try again in the 90s. 1318 01:18:49,412 --> 01:18:51,502 This time, they want better labeling and to remove 1319 01:18:51,502 --> 01:18:53,276 unsafe products. 1320 01:18:53,276 --> 01:18:55,517 But the industry fights back, claiming the regulation 1321 01:18:55,517 --> 01:19:00,282 will make it too expensive and limit consumer choice. 1322 01:19:00,282 --> 01:19:05,282 ♪ You know I wear my therapeutic promises with pride ♪ 1323 01:19:06,915 --> 01:19:11,915 ♪ But every name I have to claim discreetly qualified ♪ 1324 01:19:13,466 --> 01:19:18,466 ♪ No reason to investigate, no reason to delay ♪ 1325 01:19:20,359 --> 01:19:24,781 ♪ You might just live forever if you take me twice a day ♪ 1326 01:19:24,781 --> 01:19:29,781 ♪ Oh but I am not a medicine, I am not a drug ♪ 1327 01:19:32,108 --> 01:19:37,108 ♪ To keep me cheap you need to sweep me right under the rug ♪ 1328 01:19:38,774 --> 01:19:43,774 ♪ Hey FDA, get out the way, why can't we stay like this ♪ 1329 01:19:45,437 --> 01:19:50,437 ♪ Where I am not a medicine ♪ 1330 01:19:52,245 --> 01:19:55,662 ♪ And ignorance is bliss ♪ 1331 01:19:59,717 --> 01:20:04,717 In 1994, a new US law is passed, forbidding the testing 1332 01:20:04,957 --> 01:20:07,927 of dietary supplements for safety or effectiveness 1333 01:20:07,927 --> 01:20:08,927 before sale. 1334 01:20:15,356 --> 01:20:18,794 And the industry explodes from around 4000 products 1335 01:20:18,794 --> 01:20:19,961 to over 85000. 1336 01:20:22,499 --> 01:20:24,249 Perhaps the most surprising part about the way that 1337 01:20:24,249 --> 01:20:27,612 supplements are regulated is that it is because of 1338 01:20:27,612 --> 01:20:31,307 us consumers, we supported this legislation. 1339 01:20:31,307 --> 01:20:35,350 We lobbied on behalf of the dietary supplement industry 1340 01:20:35,350 --> 01:20:38,931 to get congress to pass a sweeping law in 1994 that 1341 01:20:38,931 --> 01:20:42,608 forever forbade the FDA from requiring that dietary 1342 01:20:42,608 --> 01:20:46,398 supplements be tested or for efficacy before they're sold. 1343 01:20:46,398 --> 01:20:48,150 What do you mean forever? 1344 01:20:48,150 --> 01:20:52,268 Like unless there's another law, that's just how it is. 1345 01:20:52,268 --> 01:20:54,685 (soft music) 1346 01:20:56,407 --> 01:21:00,406 Different countries have different regulations. 1347 01:21:00,406 --> 01:21:02,972 In Australia, most vitamin products are classified as 1348 01:21:02,972 --> 01:21:04,972 complimentary medicines. 1349 01:21:06,118 --> 01:21:08,844 Manufacturers must certify that they use low risk 1350 01:21:08,844 --> 01:21:11,458 ingredients, products contain what they say they 1351 01:21:11,458 --> 01:21:16,458 contain and they have evidence to back up health claims. 1352 01:21:16,856 --> 01:21:20,370 But, it's a trust based system. 1353 01:21:20,370 --> 01:21:23,355 Products don't have to be proven safe or effective 1354 01:21:23,355 --> 01:21:25,272 before they go on sale. 1355 01:21:29,117 --> 01:21:31,687 In Europe, vitamin products are regulated as food 1356 01:21:31,687 --> 01:21:35,207 supplements and again, they don't have to be tested 1357 01:21:35,207 --> 01:21:37,557 before they go on sale. 1358 01:21:37,557 --> 01:21:39,466 However, the laws are tougher. 1359 01:21:39,466 --> 01:21:42,207 To claim a health benefit, for example, manufacturers 1360 01:21:42,207 --> 01:21:47,110 must show proven scientific evidence, and in France, 1361 01:21:47,110 --> 01:21:49,991 high doses of vitamins generally need a medical 1362 01:21:49,991 --> 01:21:51,740 prescription. 1363 01:21:54,700 --> 01:21:56,655 But increasingly, people are buying their vitamin 1364 01:21:56,655 --> 01:21:58,447 products online. 1365 01:21:58,447 --> 01:22:00,947 (tense music) 1366 01:22:05,779 --> 01:22:09,196 So globally, it's a case of buyer beware. 1367 01:22:10,430 --> 01:22:13,462 (players shouting) 1368 01:22:13,462 --> 01:22:18,126 And yet, we can't forget that in cases of real deficiency, 1369 01:22:18,126 --> 01:22:21,459 vitamin supplements can transform lives. 1370 01:22:25,941 --> 01:22:28,441 They can save a child's sight. 1371 01:22:30,279 --> 01:22:32,279 They can be life savers. 1372 01:22:34,780 --> 01:22:38,262 But what if we're healthy, with no known deficiency? 1373 01:22:38,262 --> 01:22:42,120 How do we decide whether to take them or not? 1374 01:22:44,210 --> 01:22:47,693 My final stop is to meet experts planning the ultimate 1375 01:22:47,693 --> 01:22:48,860 human journey. 1376 01:22:51,956 --> 01:22:56,123 I wanna know, are they taking supplements to Mars? 1377 01:22:59,291 --> 01:23:00,923 And liftoff. 1378 01:23:00,923 --> 01:23:05,137 The (mumbles) of (mumbles) hit a new era of American 1379 01:23:05,137 --> 01:23:06,637 space exploration. 1380 01:23:12,356 --> 01:23:15,900 NASA is preparing to send humans to Mars 1381 01:23:15,900 --> 01:23:16,900 around 2030. 1382 01:23:19,378 --> 01:23:22,775 Imagine a three year round trip with only the food 1383 01:23:22,775 --> 01:23:25,192 you have on board to survive. 1384 01:23:26,555 --> 01:23:28,500 They can't go down the street and go to a restaurant. 1385 01:23:28,500 --> 01:23:30,773 If they don't like what you've provided, they can't go 1386 01:23:30,773 --> 01:23:34,342 to the grocery store and have hundreds of choices. 1387 01:23:34,342 --> 01:23:37,546 So this is where we freeze dry the products. 1388 01:23:37,546 --> 01:23:40,190 Dr. Grace Douglas leads NASA's research into 1389 01:23:40,190 --> 01:23:43,302 the nutritional needs of astronauts. 1390 01:23:43,302 --> 01:23:46,757 The focus is on taking whole foods into space. 1391 01:23:46,757 --> 01:23:49,588 And all of our freeze dried foods get made in this lab 1392 01:23:49,588 --> 01:23:51,950 here, so cook like you would at home and then they get put 1393 01:23:51,950 --> 01:23:56,950 in here frozen and the moisture gets pulled out of them. 1394 01:23:57,820 --> 01:24:00,250 In flight, they'll add the water back and it rehydrates 1395 01:24:00,250 --> 01:24:02,753 to be just like the meal it was before we pulled 1396 01:24:02,753 --> 01:24:04,152 the water out. 1397 01:24:04,152 --> 01:24:06,198 Some of the vitamins actually do really well through 1398 01:24:06,198 --> 01:24:07,670 this process. 1399 01:24:07,670 --> 01:24:10,753 (cheerful whistling) 1400 01:24:14,556 --> 01:24:18,999 Strawberry shortcake, ready for you, Chris. 1401 01:24:18,999 --> 01:24:20,325 I like the look of this, 1402 01:24:20,325 --> 01:24:22,242 this is your shrimp dish, is it? 1403 01:24:22,242 --> 01:24:24,518 That's shrimp cocktail. Wow, these are really 1404 01:24:24,518 --> 01:24:26,705 cool, and a burger, of course, very American. 1405 01:24:26,705 --> 01:24:28,178 Yes. 1406 01:24:28,178 --> 01:24:31,967 So this one's sweet and sour chicken. 1407 01:24:31,967 --> 01:24:36,926 Honey coming out pretty well there, there we go. 1408 01:24:36,926 --> 01:24:38,894 Chocolate pudding cake. 1409 01:24:38,894 --> 01:24:41,100 So will NASA be sending vitamin supplements 1410 01:24:41,100 --> 01:24:42,646 to Mars? 1411 01:24:42,646 --> 01:24:43,948 Pretty good. 1412 01:24:43,948 --> 01:24:45,950 The only one we send is vitamin D and that's because 1413 01:24:45,950 --> 01:24:47,836 you get a lot of your vitamin D exposure from sunlight 1414 01:24:47,836 --> 01:24:50,736 exposure on your skin and we're not gonna have that option 1415 01:24:50,736 --> 01:24:52,207 in space flight. 1416 01:24:52,207 --> 01:24:53,409 Only vitamin D? 1417 01:24:53,409 --> 01:24:56,250 Yeah, we expect that we have all the other nutrients 1418 01:24:56,250 --> 01:24:59,674 in a wide variety of a balanced food system. 1419 01:24:59,674 --> 01:25:01,836 Why is food better than supplements? 1420 01:25:01,836 --> 01:25:06,860 Food is just core and fundamental to every aspect 1421 01:25:06,953 --> 01:25:09,272 of human health and performance, so it's central 1422 01:25:09,272 --> 01:25:12,300 to these missions and there's really no way because there's 1423 01:25:12,300 --> 01:25:14,714 so many different vitamins in food, there's so many 1424 01:25:14,714 --> 01:25:17,895 things that you're getting that you can't replicate 1425 01:25:17,895 --> 01:25:19,895 at this point in a pill. 1426 01:25:20,799 --> 01:25:24,248 Okay, there we go, it says 75, so we're gonna put in 75. 1427 01:25:24,248 --> 01:25:26,936 I mean to me, it feels like the linchpin, right? 1428 01:25:26,936 --> 01:25:30,411 To determine whether a crew gets to Mars and is happy and 1429 01:25:30,411 --> 01:25:33,940 healthy and ready to go. 1430 01:25:33,940 --> 01:25:35,840 It sounds to me comes down to the food. 1431 01:25:35,840 --> 01:25:36,517 It's one of the great needs, 1432 01:25:36,517 --> 01:25:37,733 you have oxygen, water, and food, 1433 01:25:37,733 --> 01:25:39,504 and no matter what, you can't go anywhere 1434 01:25:39,504 --> 01:25:41,378 or do anything with the human system without those three 1435 01:25:41,378 --> 01:25:43,497 critical things. 1436 01:25:43,497 --> 01:25:44,330 How do you like it? 1437 01:25:44,330 --> 01:25:48,247 It's fantastic, I would eat this, absolutely. 1438 01:25:49,398 --> 01:25:50,904 For three years. 1439 01:25:50,904 --> 01:25:52,895 For three years, this is all I get? 1440 01:25:52,895 --> 01:25:53,728 Yeah. 1441 01:25:56,195 --> 01:25:57,952 This is mission control Houston. 1442 01:25:57,952 --> 01:26:00,272 As we come up on the first two critical Orion program 1443 01:26:00,272 --> 01:26:03,978 milestones, the service module faring panel jettison 1444 01:26:03,978 --> 01:26:05,962 and the launch abort system jettison-- 1445 01:26:05,962 --> 01:26:08,277 Our growing understanding of the power 1446 01:26:08,277 --> 01:26:12,270 of food is revealing something extraordinary. 1447 01:26:16,843 --> 01:26:19,979 As well as the 13 vitamins, there are thousands of other 1448 01:26:19,979 --> 01:26:24,573 chemicals in food, a multitude of molecules working 1449 01:26:24,573 --> 01:26:27,906 in complex and often mysterious synergy. 1450 01:26:30,671 --> 01:26:34,370 Together, they protect against disease, but they don't 1451 01:26:34,370 --> 01:26:37,805 always have that same power if they're isolated 1452 01:26:37,805 --> 01:26:38,972 from our food. 1453 01:26:40,988 --> 01:26:43,571 (all laughing) 1454 01:26:46,838 --> 01:26:50,869 At this point in time, we can't begin to think that a 1455 01:26:50,869 --> 01:26:54,577 supplement could replicate what we would get from a food 1456 01:26:54,577 --> 01:26:57,494 or replace whole foods in our diet. 1457 01:26:58,448 --> 01:27:02,604 Foods contain dozens of essential micronutrients, but they 1458 01:27:02,604 --> 01:27:05,997 also contain literally thousands of compounds that we've 1459 01:27:05,997 --> 01:27:10,215 only minimally studied up until this point in time. 1460 01:27:10,215 --> 01:27:12,844 Even if it's comfortable to think that this pill will 1461 01:27:12,844 --> 01:27:16,924 solve many problem of the daily life and will prevent 1462 01:27:16,924 --> 01:27:20,512 longterm or chronic diseases, and it's not true and it's not 1463 01:27:20,512 --> 01:27:23,711 proven for the moment and what is proven are the 1464 01:27:23,711 --> 01:27:26,794 relationship between diet and health. 1465 01:27:29,920 --> 01:27:31,144 I actually think it's unfortunate that there's been 1466 01:27:31,144 --> 01:27:34,863 so much hype and pseudoscience around vitamins, so you 1467 01:27:34,863 --> 01:27:39,190 have people who are evidence based, science based who think 1468 01:27:39,190 --> 01:27:42,137 "Oh, vitamins are all nonsense," no, they're not, actually, 1469 01:27:42,137 --> 01:27:45,804 it's science, it's nutrition, it's medicine. 1470 01:27:46,848 --> 01:27:51,880 What's nonsense is over hyping vitamins or pretending that 1471 01:27:51,880 --> 01:27:54,500 they're something that they're not. 1472 01:27:57,405 --> 01:27:59,595 You know, before, when I thought of vitamins, I thought 1473 01:27:59,595 --> 01:28:00,974 of pills. 1474 01:28:00,974 --> 01:28:04,300 I had kind of forgotten that they all come from food, but 1475 01:28:04,300 --> 01:28:06,490 now I've learned it's really not that hard to get everything 1476 01:28:06,490 --> 01:28:09,408 you need from food and there's so much more to food than 1477 01:28:09,408 --> 01:28:11,420 we currently understand. 1478 01:28:11,420 --> 01:28:13,782 After all, we've been getting our food from vitamins for 1479 01:28:13,782 --> 01:28:15,728 millions of years. 1480 01:28:15,728 --> 01:28:18,469 You think we'd have it all worked out in barely a hundred? 1481 01:28:18,469 --> 01:28:20,124 So should we take our vitamins? 1482 01:28:20,124 --> 01:28:21,166 Yes! 1483 01:28:21,166 --> 01:28:23,877 By eating good food, and if you feel like you need something 1484 01:28:23,877 --> 01:28:26,855 extra, maybe the best thing to do is think of vitamins 1485 01:28:26,855 --> 01:28:28,317 as if they're medicines. 1486 01:28:28,317 --> 01:28:32,234 That is, if you take them, take them seriously. 1487 01:28:34,170 --> 01:28:38,434 (people chattering under soft music) 1488 01:28:52,338 --> 01:28:54,838 (tense music) 121250

Can't find what you're looking for?
Get subtitles in any language from opensubtitles.com, and translate them here.