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These are the user uploaded subtitles that are being translated: 1 00:00:01,784 --> 00:00:05,875 [THUNDER ROLLING SOUND] 2 00:00:15,015 --> 00:00:18,192 [WIND/WHIRRING SOUNDS INCREASE] 3 00:00:21,978 --> 00:00:25,025 ♪PIANO MUSIC PLAYS WITH DISTANT TALKING♪ 4 00:00:36,471 --> 00:00:40,779 ♪MELANCHOLY PIANO CONTINUES 5 00:00:44,261 --> 00:00:49,266 MOM: Oh My God. 6 00:01:00,277 --> 00:01:03,193 [BIRDS CHIRPING] 7 00:01:08,720 --> 00:01:11,549 [BUBBLING SOUNDS] 8 00:01:27,130 --> 00:01:29,785 ♪PIANO MUSIC CONTINUES 9 00:01:36,139 --> 00:01:38,968 [LIGHT GLITCHY SOUNDS EFFECTS] 10 00:01:42,493 --> 00:01:44,626 [GLITCHY SOUND EFFECT] 11 00:01:51,415 --> 00:01:54,897 [GLITCHES INTENSIFY] 12 00:02:14,221 --> 00:02:18,660 [RUSTY SWINGS SOUNDS AND CHILD CHATTER] 13 00:02:20,836 --> 00:02:23,012 [BUZZING GLITCH] 14 00:02:33,196 --> 00:02:35,894 [DOOR KNOCKS] 15 00:02:43,554 --> 00:02:48,516 DELIVERY MAN: Delivery. 16 00:02:50,561 --> 00:02:52,563 Delivery. 17 00:03:10,233 --> 00:03:13,845 ♪MELANCHOLY PIANO MUSIC PLAYS 18 00:03:30,601 --> 00:03:33,952 ♪PIANO MUSIC CONTINUES 19 00:03:42,831 --> 00:03:46,965 HENRY: Pain. Suffering due to bodily harm. 20 00:03:48,924 --> 00:03:53,581 Symptoms can be sharp. Stabbing. Shooting. 21 00:03:53,624 --> 00:03:56,714 Burning. 22 00:03:56,758 --> 00:04:02,590 Causes can be cutaneous, an injury to the skin: somatic, 23 00:04:02,633 --> 00:04:07,464 originating from the bones, ligaments, or muscle: or 24 00:04:07,508 --> 00:04:11,294 visceral, from the organs. 25 00:04:11,338 --> 00:04:14,341 [CELL PHONE BUZZING] 26 00:04:16,995 --> 00:04:21,043 It's nature's way of protecting us, of teaching us how to 27 00:04:21,086 --> 00:04:23,132 protect ourselves. 28 00:04:25,656 --> 00:04:30,748 But every once in a while, nature makes a mistake. 29 00:04:35,057 --> 00:04:36,450 ♪DEEP BASS TECHNO LIKE MUSIC 30 00:04:54,206 --> 00:04:58,820 ♪DEEP BASS TECHNO LIKE MUSIC CONTINUES♪ 31 00:04:58,863 --> 00:05:01,866 [CAR HONK] 32 00:05:31,461 --> 00:05:33,681 [DOOR BELL SOUND] 33 00:05:36,118 --> 00:05:38,990 When's the last time you had your thyroid checked? 34 00:05:39,600 --> 00:05:41,732 Hand tremors, weak upper arms, brittle hair. That's all 35 00:05:41,776 --> 00:05:43,343 signs of hyperthyroidism. 36 00:05:43,386 --> 00:05:46,346 Your immune system could be attacking itself right now. 37 00:05:46,389 --> 00:05:48,609 CLERK: Is that serious? 38 00:05:49,784 --> 00:05:54,310 If you take radioactive iodine soon enough, you should be fine. 39 00:05:54,354 --> 00:05:57,705 There you go. Keep the change. 40 00:05:57,748 --> 00:06:01,143 ♪MELANCHOLY MUSIC PLAYS 41 00:06:03,406 --> 00:06:07,062 There are over a hundred billion nerves in the human body. 42 00:06:07,105 --> 00:06:10,413 Sensors in these nerves detect pain and transmit the signal 43 00:06:10,457 --> 00:06:13,764 along the spinal cord to the brain. 44 00:06:18,421 --> 00:06:20,380 Everyone has a tale. 45 00:06:21,424 --> 00:06:24,209 You just have to know how to see it. 46 00:06:31,695 --> 00:06:35,177 ♪PIANO MUSIC CONTINUES 47 00:06:52,890 --> 00:06:55,023 [PHONE BUZZING] 48 00:07:00,289 --> 00:07:03,771 ♪UPBEAT TECHNO MUSIC PLAYS 49 00:07:11,213 --> 00:07:17,088 ♪UPBEAT TECHNO MUSIC INTENSIFIES♪ 50 00:07:27,490 --> 00:07:29,623 EDDIE: You're a genius, Henry, you know that? 51 00:07:29,666 --> 00:07:33,061 Sometimes I forget how much pain I'm until it's gone. 52 00:07:33,104 --> 00:07:35,585 I don't know what I'd do without you. 53 00:07:37,152 --> 00:07:40,111 There's this guy I've been meaning to talk to you about. 54 00:07:40,155 --> 00:07:42,766 He's well connected. He deals strictly in 55 00:07:42,810 --> 00:07:45,116 pharmaceuticals. No tweaker shit. 56 00:07:45,160 --> 00:07:48,511 I don't have time for distractions. 57 00:07:51,035 --> 00:07:53,690 Since when is money a distraction? 58 00:07:58,913 --> 00:08:03,570 HENRY: In a dream they say to pinch yourself to know you're asleep. 59 00:08:05,006 --> 00:08:08,575 If you couldn't feel any pain, how would you ever know you're 60 00:08:08,618 --> 00:08:11,142 awake? 61 00:08:11,186 --> 00:08:18,889 SHANI: Whoa, sorry. Oh, my God, your hand! Are you okay? 62 00:08:18,933 --> 00:08:20,978 Yeah, I'm, fine. Thank you. 63 00:08:21,022 --> 00:08:25,156 Are you sure? 64 00:08:32,555 --> 00:08:35,166 The skin can continue to burn more than five minutes after a 65 00:08:35,210 --> 00:08:37,168 scalding liquid has been removed from it. 66 00:08:37,212 --> 00:08:39,301 If it is not treated immediately, it can affect the 67 00:08:39,344 --> 00:08:41,695 underlying layer of the skin, leading to serious 68 00:08:41,738 --> 00:08:43,958 complications. 69 00:08:52,227 --> 00:08:54,403 You sure you're okay? 70 00:08:57,145 --> 00:08:59,495 Does it hurt? 71 00:08:59,539 --> 00:09:04,587 No. It's okay. It's okay, really. 72 00:09:04,631 --> 00:09:07,721 What, are you some kind of doctor or something? 73 00:09:09,810 --> 00:09:11,899 Cautious. 74 00:09:13,944 --> 00:09:17,426 You wouldn't happen to have any aspirin in there, would you? 75 00:09:20,298 --> 00:09:24,302 What? 76 00:09:24,346 --> 00:09:28,698 That's probably the only medication I don't have. 77 00:09:29,003 --> 00:09:31,919 Don't get headaches? 78 00:09:31,962 --> 00:09:35,096 Not too often. 79 00:09:35,139 --> 00:09:38,795 You know, you didn't even flinch back there. 80 00:09:38,839 --> 00:09:41,102 It was like you didn't even notice. 81 00:09:41,145 --> 00:09:44,235 No, I noticed. 82 00:09:44,279 --> 00:09:48,631 Well, like I said, sorry. 83 00:09:48,675 --> 00:09:52,113 No, wait. Wait, wait. 84 00:09:55,246 --> 00:10:00,295 Here. For your headaches. 85 00:10:00,338 --> 00:10:03,994 What is this, like some kind of Chinese medicine or something? 86 00:10:04,038 --> 00:10:09,130 Something like that. Good for your shoulder too. 87 00:10:14,265 --> 00:10:20,968 Thanks. I should go. I still got three stops. 88 00:10:24,232 --> 00:10:26,843 You know, I didn't get your name. 89 00:10:26,887 --> 00:10:28,497 Henry. 90 00:10:28,540 --> 00:10:36,244 Henry. I'm Shani. Maybe I'll see you around. 91 00:10:58,875 --> 00:11:03,663 Aristotle said "We cannot learn without pain." 92 00:11:03,706 --> 00:11:08,668 It is the single unifying thread that connects all organisms. 93 00:11:08,711 --> 00:11:14,804 Even fish experience pain. What does that make me? 94 00:11:18,068 --> 00:11:20,941 [MELANCHOLY AMBIENCE] 95 00:11:32,953 --> 00:11:35,695 [PHONE RINGS] 96 00:11:35,738 --> 00:11:42,005 RECEPTIONIST: Dr. Raymond Parks' office. Mm-hmm. Okay. 97 00:11:42,049 --> 00:11:45,182 We will see you then. 98 00:12:06,334 --> 00:12:10,730 DR. PARKS: Okay. Henry, how you doing? 99 00:12:10,773 --> 00:12:15,212 I've tested all the Naloxone derivatives. Nothing. 100 00:12:15,256 --> 00:12:17,432 You're going to kill those damn mice. All right. 101 00:12:17,475 --> 00:12:20,435 Get up here and let's take a look at you. 102 00:12:26,789 --> 00:12:28,791 -What happened there? -I don't think it's a big deal. 103 00:12:28,835 --> 00:12:32,360 I dressed it yesterday. It's a coffee burn. 104 00:12:32,403 --> 00:12:35,493 DR. PARKS: Yeah, it looks good. 105 00:12:36,320 --> 00:12:40,411 So what's with the, uh, weight shifter out there? 106 00:12:40,455 --> 00:12:42,370 What do mean? My new patient? 107 00:12:42,413 --> 00:12:46,809 I mean, her inability to sit up straight could suggest 108 00:12:46,853 --> 00:12:49,638 she's suffering from sciatica. 109 00:12:49,681 --> 00:12:51,509 Well that is the diagnosis. 110 00:12:51,553 --> 00:12:55,035 Of course, spinal stenosis would show a lot of the 111 00:12:55,078 --> 00:12:57,777 same symptoms, and be more difficult to diagnose. 112 00:12:57,820 --> 00:12:59,822 -Sciatica is more likely. -It would also explain the 113 00:12:59,866 --> 00:13:01,868 fact that she leans slightly forward when she walks to 114 00:13:01,911 --> 00:13:04,696 alleviate her pain instead of stiffly upright like someone 115 00:13:04,740 --> 00:13:06,960 with sciatica would. You'd just have to MRI her lower 116 00:13:07,003 --> 00:13:08,744 thoracic region. 117 00:13:08,788 --> 00:13:12,530 Actually, that is interesting. Now, have you given some more 118 00:13:12,574 --> 00:13:14,532 thought to Maine? 119 00:13:14,576 --> 00:13:17,535 No. 120 00:13:17,579 --> 00:13:20,930 Henry, do you realize the strings I have pulled just 121 00:13:20,974 --> 00:13:25,152 to get them to talk to you? The Fall River Center is one of the 122 00:13:25,195 --> 00:13:27,589 greatest hospitals in the country for children with rare 123 00:13:27,632 --> 00:13:30,113 diseases. You could be a role model. 124 00:13:33,203 --> 00:13:36,032 Look at this. You can help these kids, huh? 125 00:13:36,076 --> 00:13:38,513 You know what they're going through. 126 00:13:38,556 --> 00:13:40,384 You talk to them? Huh? 127 00:13:40,863 --> 00:13:43,387 Yeah, fine. I will, I promise. 128 00:13:43,431 --> 00:13:46,651 That's all I can ask. Sit back. 129 00:13:46,695 --> 00:13:50,046 What if we just up the dosages? 130 00:13:50,090 --> 00:13:51,482 What are they currently? 131 00:13:51,526 --> 00:13:53,615 53 milligrams per kilogram. 132 00:13:53,658 --> 00:13:55,530 No, no, no. That's too toxic. 133 00:13:55,573 --> 00:13:58,663 Unless you came up with a similar derivative that 134 00:13:58,707 --> 00:14:03,103 could bond with the receptors at a slower rate. 135 00:14:03,146 --> 00:14:05,453 Naltrexone has a similar structure. 136 00:14:05,496 --> 00:14:07,934 No. That's for alcohol dependence. 137 00:14:07,977 --> 00:14:10,023 But I could create a set of derivatives from it. 138 00:14:10,066 --> 00:14:14,244 All I would need is -- is a -- is a precursor. 139 00:14:19,902 --> 00:14:23,950 DR. ANDREWS: Henry. Henry Long? 140 00:14:25,081 --> 00:14:31,958 My name is Andrews. Dr. Stephen Andrews. Please. 141 00:14:42,490 --> 00:14:43,926 You're a research scientist? 142 00:14:43,970 --> 00:14:46,059 Sorry. I didn't mean to alarm you. 143 00:14:46,102 --> 00:14:48,888 I just needed to make sure you are the right candidate. 144 00:14:48,931 --> 00:14:50,454 Candidate for what? 145 00:14:50,498 --> 00:14:52,674 Well, as you know, in recent years we've made great strides 146 00:14:52,717 --> 00:14:54,894 in the field of pain management, but that's it. 147 00:14:54,937 --> 00:14:58,201 We've reached an apex. There's no where left to go. 148 00:14:58,245 --> 00:15:00,116 What's this got to do with me? 149 00:15:00,160 --> 00:15:04,555 In all my years, I've never come across anyone like you. 150 00:15:04,599 --> 00:15:07,994 A body immune to pain in every way, and a healthy adult body to 151 00:15:08,037 --> 00:15:09,430 boot. 152 00:15:09,473 --> 00:15:12,128 Do you realize how rare that is? 153 00:15:12,172 --> 00:15:13,782 How did you-- 154 00:15:13,825 --> 00:15:16,654 Well, just because the world has forgotten about Raymond doesn't 155 00:15:16,698 --> 00:15:19,962 mean I don't occasionally still keep tabs on him. 156 00:15:20,006 --> 00:15:22,617 I'm not surprised he never mentioned me though. 157 00:15:22,660 --> 00:15:24,880 We didn't part on good terms. 158 00:15:24,924 --> 00:15:27,013 So what do you want from me? 159 00:15:27,056 --> 00:15:30,625 I want to offer you a chance. A chance to help thousands, 160 00:15:30,668 --> 00:15:34,107 maybe millions of people. 161 00:15:34,150 --> 00:15:36,674 You want to study me? 162 00:15:37,153 --> 00:15:39,329 I promise you will be handsomely rewarded. 163 00:15:39,373 --> 00:15:42,071 I don't have time for distractions. 164 00:15:42,115 --> 00:15:43,594 Think of all the people you could help. 165 00:15:43,638 --> 00:15:45,945 Doesn't that mean anything to you? 166 00:15:45,988 --> 00:15:47,990 No. 167 00:15:48,034 --> 00:15:49,470 [UPBEAT TECHNO MUSIC] 168 00:15:49,513 --> 00:15:52,777 If it is possible to dull the body's senses, then 169 00:15:52,821 --> 00:15:55,345 the opposite must also be true. 170 00:15:55,389 --> 00:15:59,088 If we can take away the sensation of pain, then we must 171 00:15:59,132 --> 00:16:02,265 also be able to create it. 172 00:16:06,008 --> 00:16:08,880 [PHONE BUZZING] 173 00:16:11,361 --> 00:16:13,189 Hello? 174 00:16:13,233 --> 00:16:15,931 DR. LIN: Hi, Henry. This is Dr. Lin from The Fall River Medical Center. 175 00:16:15,975 --> 00:16:20,022 I believe Dr. Parks told you to expect our call. 176 00:16:20,066 --> 00:16:23,286 I'm sure Raymond mentioned our facility offers children with 177 00:16:23,330 --> 00:16:26,376 rare diseases some of the greatest care in the world. 178 00:16:26,420 --> 00:16:28,465 We'd love it if you could find the time to come by -- 179 00:16:28,509 --> 00:16:29,771 Thebaine. 180 00:16:29,814 --> 00:16:33,166 Excuse me? 181 00:16:33,209 --> 00:16:36,996 -Uh, sorry. I gotta go. -But -- 182 00:16:53,447 --> 00:16:55,449 RECEPTIONIST: Hey! 183 00:16:57,364 --> 00:17:00,106 Let me -- let me call you back. Yeah. 184 00:17:01,150 --> 00:17:02,325 I'm sorry, Doctor. 185 00:17:02,369 --> 00:17:04,458 It's all right, Paulina. 186 00:17:06,851 --> 00:17:09,245 You know, she hates it when you do that. 187 00:17:09,289 --> 00:17:10,855 I need Thebaine. 188 00:17:10,899 --> 00:17:14,033 Thebaine is a precursor to morphine and codeine. 189 00:17:14,076 --> 00:17:16,078 You planning on getting in the heroin business? 190 00:17:16,122 --> 00:17:19,864 It's also a precursor to Naltrexone. 191 00:17:20,778 --> 00:17:23,346 Sit down. Henry. 192 00:17:28,612 --> 00:17:31,267 All right. It's an interesting idea. 193 00:17:31,311 --> 00:17:34,662 I'll give you that. Unfortunately, it's a controlled 194 00:17:34,705 --> 00:17:38,274 substance. I can't just write you a prescription. 195 00:17:38,318 --> 00:17:41,843 Yeah, but you must know somebody from back in the day. 196 00:17:41,886 --> 00:17:45,673 I can't just call one of my colleagues out of the blue and 197 00:17:45,716 --> 00:17:49,459 ask for something like that. I could lose my license. 198 00:17:49,503 --> 00:17:54,551 Worse, I could go to jail. Now, what you should do, come up 199 00:17:54,595 --> 00:17:56,162 with a proposal. 200 00:17:56,205 --> 00:17:58,207 Submit it to a pharmaceutical company. 201 00:17:58,251 --> 00:18:01,776 There isn't a pharmaceutical company in the world who would 202 00:18:01,819 --> 00:18:03,778 put two cents into a project like this, and 203 00:18:03,821 --> 00:18:06,607 you know that because there's not enough people like me to 204 00:18:06,650 --> 00:18:08,130 make it profitable. 205 00:18:08,174 --> 00:18:11,307 First rule in being a good scientist is not letting your 206 00:18:11,351 --> 00:18:14,745 emotions cloud your judgment. You're too close to this. 207 00:18:14,789 --> 00:18:18,184 You gotta step back. Get out of your house. 208 00:18:18,227 --> 00:18:20,490 How did it go with, uh, The Fall River Center? 209 00:18:20,534 --> 00:18:22,797 Who's Dr. Andrews? 210 00:18:27,149 --> 00:18:28,977 Where'd you hear that name? 211 00:18:29,020 --> 00:18:31,197 He approached me. 212 00:18:31,545 --> 00:18:32,937 For what? 213 00:18:34,200 --> 00:18:36,419 A research project he's doing. 214 00:18:36,463 --> 00:18:38,465 And what did you tell him? 215 00:18:38,769 --> 00:18:41,598 I told him I wasn't interested. 216 00:18:41,642 --> 00:18:43,513 Good. 217 00:18:44,949 --> 00:18:47,561 Do yourself a favor. Get that crazy idea out 218 00:18:47,604 --> 00:18:51,391 of your head before you do something stupid. 219 00:18:53,088 --> 00:18:56,526 And Henry, 220 00:18:56,570 --> 00:18:59,312 next time make an appointment. 221 00:19:01,662 --> 00:19:03,968 [CITY NOISE] 222 00:19:05,187 --> 00:19:07,276 [DOOR KNOCKING] 223 00:19:13,239 --> 00:19:15,110 I need your help. 224 00:19:21,595 --> 00:19:23,162 I'm listening. 225 00:19:23,727 --> 00:19:27,166 I need you to get me something called Thebaine. 226 00:19:27,209 --> 00:19:28,819 It's a chemical. 227 00:19:29,907 --> 00:19:32,040 You're the scientist. That's your department. 228 00:19:32,823 --> 00:19:35,696 It's a controlled substance. 229 00:19:36,697 --> 00:19:38,307 So what does that have to do with me? 230 00:19:39,613 --> 00:19:41,615 You're a drug dealer. 231 00:19:41,658 --> 00:19:44,444 Fuck you. I'm not a drug dealer. I just deal what you give me. 232 00:19:44,487 --> 00:19:47,534 Would there be anybody you know who could get it? 233 00:19:47,577 --> 00:19:50,189 The only people I know are pill popping junkies. 234 00:19:50,232 --> 00:19:52,669 That's about it. But while you're here, 235 00:19:52,713 --> 00:19:54,367 why don't we talk about something more important like 236 00:19:54,410 --> 00:19:58,240 you getting me more of my suppl -- God damn it. 237 00:19:59,154 --> 00:20:01,983 [TIRES SCREECH, DOGS BARKING] 238 00:20:12,776 --> 00:20:16,258 ♪UPBEAT TECHNO MUSIC PLAYS 239 00:20:28,705 --> 00:20:32,666 ♪UPBEAT TECHNO MUSIC CONTINUES 240 00:20:35,930 --> 00:20:39,150 I'm outside. 241 00:20:43,285 --> 00:20:45,418 [DOOR BUZZING] 242 00:20:53,948 --> 00:20:58,866 Hello, Henry. I'm so glad you could make it. Please. 243 00:21:05,699 --> 00:21:07,309 This is your lab? 244 00:21:07,353 --> 00:21:10,356 Oh, it -- it's not much, but we tend to operate under the radar. 245 00:21:10,399 --> 00:21:12,619 This is Jeremy, my assistant. 246 00:21:12,662 --> 00:21:14,577 What kind of tests are we talking about? 247 00:21:14,621 --> 00:21:19,190 All very standard. Nothing much. Completely noninvasive. 248 00:21:19,234 --> 00:21:23,847 Thebaine. Schedule II. 249 00:21:23,891 --> 00:21:28,287 We thought we'd come to some sort of a financial arrangement. 250 00:21:28,330 --> 00:21:33,640 That's my price. Can you get it or not? 251 00:21:33,683 --> 00:21:35,555 It would take some time but -- yes. 252 00:21:35,598 --> 00:21:38,471 JEREMY: Uh, wait -- wait, you're actually considering this? 253 00:21:38,514 --> 00:21:40,864 So we have a deal? 254 00:21:40,908 --> 00:21:43,302 Yes. We have a deal. 255 00:21:43,345 --> 00:21:46,435 One more thing. This is a one-time arrangement. 256 00:21:46,479 --> 00:21:51,310 After this you never contact me again. Ever. 257 00:21:51,353 --> 00:21:52,876 Okay? 258 00:21:55,357 --> 00:22:00,449 Sounds reasonable. Now then, let's get started, shall we? 259 00:22:08,022 --> 00:22:11,330 [MELANCHOLY AMBIENCE PLAYS] 260 00:22:11,373 --> 00:22:14,898 The hardest part is the waiting. 261 00:22:15,377 --> 00:22:19,120 Not knowing if you're going forwards or backwards. 262 00:22:25,082 --> 00:22:27,433 Stuck in limbo. 263 00:22:31,785 --> 00:22:39,793 [MELANCHOLY AMBIENCE CONTINUES] 264 00:22:59,073 --> 00:23:01,771 [PHONE BUZZES] 265 00:23:01,815 --> 00:23:06,123 When you're not like anyone else, everything is a threat. 266 00:23:06,167 --> 00:23:09,736 Especially people. 267 00:23:11,433 --> 00:23:14,784 You don't need them any more than they need you. 268 00:23:19,441 --> 00:23:22,575 Keep some pressure on that. 269 00:23:31,453 --> 00:23:33,803 When am I gonna get what was promised? 270 00:23:33,847 --> 00:23:38,591 Soon, Henry, soon. These things take time. 271 00:23:39,156 --> 00:23:43,334 Look, I -- I recognize how difficult this must be for you. 272 00:23:44,510 --> 00:23:47,208 You don't know the first thing about me. 273 00:23:47,861 --> 00:23:52,474 Henry, I've seen your gift for diagnosing. 274 00:23:52,518 --> 00:23:57,261 You must have come up with some theories on my predicament. 275 00:23:59,133 --> 00:24:03,398 Indulge me. Take a guess. Come on. 276 00:24:06,967 --> 00:24:09,448 Your pain is obviously chronic. It's capricious. 277 00:24:09,491 --> 00:24:12,059 It's not localized. My best guess is arthritis, but you 278 00:24:12,102 --> 00:24:14,453 don't show any signs of swelling, so -- 279 00:24:14,496 --> 00:24:16,803 You're not trying. You're a scientist. Push yourself. 280 00:24:16,846 --> 00:24:18,761 I don't know. 281 00:24:19,893 --> 00:24:24,027 It isn't musculoskeletal. 282 00:24:25,072 --> 00:24:32,471 It's neuropathic? You have allodynia? 283 00:24:32,514 --> 00:24:35,256 A condition not so unlike your own, really. 284 00:24:35,299 --> 00:24:38,085 Only whereas in your case your body doesn't receive pain 285 00:24:38,128 --> 00:24:41,741 signals, mine won't stop transmitting them. 286 00:24:44,091 --> 00:24:46,136 I know how difficult it can be when you're 287 00:24:46,180 --> 00:24:50,271 not like anyone else. It makes you angry. 288 00:24:51,490 --> 00:24:55,494 Afraid. I know. 289 00:24:58,366 --> 00:25:01,848 But you see, that -- that's what I admire about you. 290 00:25:01,891 --> 00:25:05,199 You're here, despite your fear. 291 00:25:06,940 --> 00:25:08,811 I'm not afraid. 292 00:25:09,333 --> 00:25:14,556 Everyone is afraid. Edison was afraid of the dark, 293 00:25:14,600 --> 00:25:16,515 did you know that? 294 00:25:17,211 --> 00:25:19,561 Know what he did about it? 295 00:25:20,736 --> 00:25:23,347 He lit up the night. 296 00:25:26,307 --> 00:25:31,617 [MYSTICAL AMBIENCE PLAYS] 297 00:25:55,249 --> 00:25:59,122 ♪COOL RETRO DANCE MUSIC 298 00:26:05,825 --> 00:26:09,089 SHANI: Hi. You know what you want? 299 00:26:09,132 --> 00:26:11,787 Uh, coffee? 300 00:26:11,831 --> 00:26:13,789 Pretty sure we can do that here. 301 00:26:15,617 --> 00:26:22,755 Hey, I know you. Henry, right? Shani. 302 00:26:22,798 --> 00:26:26,062 Right. Yeah. 303 00:26:26,628 --> 00:26:30,589 What are you doing here? You're not stalking me, are you? 304 00:26:30,632 --> 00:26:31,764 No, of course not. I -- 305 00:26:31,807 --> 00:26:34,593 I'm kidding. 306 00:26:34,636 --> 00:26:36,420 Yeah, I know. 307 00:26:37,987 --> 00:26:40,381 How's the hand? 308 00:26:40,424 --> 00:26:46,474 Oh, it's fine. How's, uh, how's your shoulder? 309 00:26:48,998 --> 00:26:50,434 Fine. 310 00:26:53,568 --> 00:26:55,483 Let's see what I can do about that coffee. 311 00:26:55,526 --> 00:26:57,267 Okay. 312 00:27:03,665 --> 00:27:07,669 ♪COFFEE HOUSE MUSIC PLAYS 313 00:27:12,935 --> 00:27:16,286 You mind? I could really use a break. 314 00:27:16,330 --> 00:27:19,072 Unless you'd rather be alone? 315 00:27:19,115 --> 00:27:21,335 No, no. I, uh -- 316 00:27:21,378 --> 00:27:24,338 It's fine? 317 00:27:28,037 --> 00:27:36,219 So, Henry, tell me about yourself. 318 00:27:36,263 --> 00:27:41,050 Um, well, I'm a scientist. 319 00:27:41,094 --> 00:27:44,837 A scientist? That's really interesting. Which field? 320 00:27:49,102 --> 00:27:51,626 I didn't want to burn myself. 321 00:27:52,105 --> 00:27:55,543 That's actually not a bad idea. I burn myself all the 322 00:27:55,586 --> 00:27:59,547 time. And occasionally others as well. 323 00:28:05,814 --> 00:28:07,642 Did you know that an average glass of water actually has 15 324 00:28:07,686 --> 00:28:10,906 different kinds of medications in it? 325 00:28:10,950 --> 00:28:12,386 Is that right? 326 00:28:12,429 --> 00:28:14,475 Yeah. I mean, most people don't know that, and it's 327 00:28:14,518 --> 00:28:16,433 partially because of all the prescriptions that people flush, 328 00:28:16,477 --> 00:28:19,219 but it's also from urinating. 329 00:28:19,262 --> 00:28:22,004 You sure know a lot about water. 330 00:28:22,918 --> 00:28:24,746 I guess. 331 00:28:25,878 --> 00:28:28,228 Well, we've all gotta hydrate, right? 332 00:28:28,271 --> 00:28:30,491 Well, actually, coffee's a diuretic, so you'd be 333 00:28:30,534 --> 00:28:33,407 dehydrating yourself. 334 00:28:34,408 --> 00:28:39,892 You're kind of strange, aren't you? What else do you do? 335 00:28:39,935 --> 00:28:42,372 Like, what do you do or fun? 336 00:28:45,332 --> 00:28:48,465 To be honest, I like to read. 337 00:28:48,509 --> 00:28:50,554 Yeah? Like what? 338 00:28:50,598 --> 00:28:53,732 Oh, all kinds of things. Science and medical journals, 339 00:28:53,775 --> 00:28:55,646 books on anatomy, medicinal chemistry, clinical 340 00:28:55,690 --> 00:28:57,953 pharmacology-- -Do you like to go out? 341 00:28:58,780 --> 00:29:06,048 Oh, I get it. 342 00:29:06,092 --> 00:29:08,921 I'm kind of focused on my work right now. 343 00:29:08,964 --> 00:29:13,621 Hmm. Not exactly a people person are you? 344 00:29:14,840 --> 00:29:17,843 There's a lot more to life than work, you know? 345 00:29:18,800 --> 00:29:19,975 Like what? 346 00:29:27,417 --> 00:29:29,506 I'll tell you what. 347 00:29:35,904 --> 00:29:37,950 My number. 348 00:29:39,299 --> 00:29:41,605 In case you want to find out sometime. 349 00:29:45,609 --> 00:29:49,483 ♪COFFEE SHOP MUSIC PLAYS 350 00:29:50,484 --> 00:29:52,791 We're going to need more blood work. 351 00:29:56,795 --> 00:29:59,319 Henry, are you listening? 352 00:30:01,234 --> 00:30:03,105 If you don't mind, Jeremy's waiting so -- 353 00:30:03,149 --> 00:30:07,196 No. No more tests. 354 00:30:07,240 --> 00:30:08,415 Henry -- 355 00:30:08,458 --> 00:30:09,459 I've given you everything you've asked for. 356 00:30:09,503 --> 00:30:12,288 I want what was promised. 357 00:30:20,557 --> 00:30:23,169 You know, for the longest time I couldn't imagine what you could 358 00:30:23,212 --> 00:30:26,868 possibly want with something like this, other than the 359 00:30:26,912 --> 00:30:28,435 obvious. 360 00:30:28,478 --> 00:30:32,178 And then it occurred to me. If one were to play with the 361 00:30:32,221 --> 00:30:37,444 sterics and electronics of an opioid receptor like Naloxone, a 362 00:30:37,487 --> 00:30:42,710 precursor could allow them to create a better derivative. 363 00:30:42,753 --> 00:30:46,932 I think you're trying to cure yourself. I can help. 364 00:30:48,237 --> 00:30:49,848 I don't need your help. 365 00:30:53,373 --> 00:30:55,244 Henry -- 366 00:30:57,899 --> 00:30:59,466 ♪UPBEAT TECHNO MUSIC PLAYS 367 00:30:59,509 --> 00:31:02,599 If it is possible to dull the body's senses, than the opposite 368 00:31:02,643 --> 00:31:04,384 must also be true. 369 00:31:04,427 --> 00:31:07,604 If we can take away the sensation of pain, then we must 370 00:31:07,648 --> 00:31:11,173 also be able to create it. 371 00:31:14,655 --> 00:31:18,050 ♪UPBEAT TECHNO MUSIC CONTINUES 372 00:31:48,558 --> 00:31:54,695 Um, hi. Um -- yeah, right. Yeah. 373 00:31:55,261 --> 00:31:57,741 ♪TECHNO LIKE AMBIENCE PLAYS♪ 374 00:32:27,946 --> 00:32:34,256 ♪MUSIC AMBIENCE INTENSIFIES 375 00:32:58,977 --> 00:33:03,111 ♪MUSIC AMBIENCE FADES 376 00:33:15,689 --> 00:33:17,212 You made it. 377 00:33:19,388 --> 00:33:22,304 Someone told me I should go out more. So -- 378 00:33:23,131 --> 00:33:26,004 Well, I could certainly use the extra hands. 379 00:33:28,963 --> 00:33:31,792 Aren't you hot? 380 00:33:31,835 --> 00:33:33,098 What do you mean? 381 00:33:33,837 --> 00:33:36,797 SHANI: We're in a greenhouse. 382 00:33:37,493 --> 00:33:41,497 -I know. -Come here. 383 00:33:51,594 --> 00:33:55,033 Did you have any trouble finding the place? 384 00:33:55,076 --> 00:33:56,599 No. No. 385 00:33:57,600 --> 00:33:59,820 Whose place is this? 386 00:33:59,863 --> 00:34:03,041 Uh, it's a community greenhouse, but I've been coming 387 00:34:03,084 --> 00:34:07,045 here as long as I can remember, so it kind of feels like mine. 388 00:34:09,134 --> 00:34:13,181 I remember when I was a kid, I would just come in here and just 389 00:34:13,225 --> 00:34:19,448 sit for hours, just really breathe it all in. 390 00:34:20,797 --> 00:34:25,367 Being around the plants just would really help put everything 391 00:34:25,411 --> 00:34:29,458 else in perspective. 392 00:34:29,502 --> 00:34:31,808 Must sound kind of strange, huh? 393 00:34:33,506 --> 00:34:36,465 It doesn't sound strange at all. 394 00:34:37,118 --> 00:34:39,686 What are you spraying on all of them? 395 00:34:39,729 --> 00:34:43,429 The bugs have been really persistent this season. 396 00:34:43,472 --> 00:34:48,303 Especially the aphids. This is a horticultural spray that I made. 397 00:34:48,347 --> 00:34:50,088 I just use it to keep them away. 398 00:34:50,349 --> 00:34:51,872 You made it? 399 00:34:51,915 --> 00:34:55,571 Yeah. It's organic, non-toxic. 400 00:34:55,615 --> 00:34:57,878 The bugs don't like it and the plants do. 401 00:34:58,966 --> 00:35:01,186 Why don't you just spray a pesticide then and get rid of 402 00:35:01,229 --> 00:35:02,491 the bugs for good? 403 00:35:04,189 --> 00:35:05,755 Then it wouldn't be natural. 404 00:35:06,321 --> 00:35:09,107 No. But that's the point of science. You find the flaws 405 00:35:09,150 --> 00:35:10,499 in nature and you fix them. 406 00:35:11,283 --> 00:35:12,458 Flaws? 407 00:35:13,241 --> 00:35:14,764 Yeah. 408 00:35:25,166 --> 00:35:28,822 Thank you for inviting me, by the way. I really enjoyed it. 409 00:35:32,260 --> 00:35:34,044 Do you want a ride? 410 00:35:34,871 --> 00:35:36,743 A ride? Yeah, sure. 411 00:35:36,786 --> 00:35:38,397 That's me. 412 00:35:43,402 --> 00:35:45,578 What's wrong? 413 00:35:45,621 --> 00:35:51,061 No, nothing. I, um, I just have a lot of work I have to do, and, 414 00:35:51,105 --> 00:35:54,239 um, I -- I live -- 415 00:35:56,589 --> 00:35:58,765 I'll take you anywhere you want to go. 416 00:36:02,334 --> 00:36:06,251 Come on. What do you say? 417 00:36:09,471 --> 00:36:11,821 [MELANCHOLY AMBIENCE CREEPS IN] 418 00:36:17,566 --> 00:36:20,743 ♪LOW TECHNO DRONING MUSIC 419 00:36:39,849 --> 00:36:43,244 ♪MELANCHOLY TECHNO MUSIC CONTINUES♪ 420 00:36:54,168 --> 00:36:57,824 ♪MUSIC INTENSIFIES TO BUZZING DRONE♪ 421 00:37:11,751 --> 00:37:13,231 DR. ANDREWS: You checked the sodium levels? 422 00:37:13,274 --> 00:37:15,015 Mm-hmm. 423 00:37:15,276 --> 00:37:17,235 Well, you're going to have to check again. 424 00:37:23,284 --> 00:37:25,765 Henry, you're back. 425 00:37:25,808 --> 00:37:28,246 I need your help. 426 00:37:39,300 --> 00:37:41,433 We're ready. 427 00:37:42,956 --> 00:37:45,263 Are you sure you don't want any anesthesia? 428 00:37:46,960 --> 00:37:50,224 Kind of defeats the purpose, don't you think? 429 00:37:50,268 --> 00:37:54,097 Believe me, if this works, you're gonna wish you had it. 430 00:37:55,838 --> 00:37:58,493 [LIGHT SUSPENSEFUL AMBIENCE] 431 00:38:18,426 --> 00:38:25,172 [DRILLING SOUNDS] 432 00:38:44,017 --> 00:38:52,547 We're in. Stimulating the parietoinsular cortex now. 433 00:38:58,205 --> 00:39:01,339 [LIGHT AMBIENCE CONTINUES] 434 00:39:14,395 --> 00:39:16,397 What? What's wrong? 435 00:39:16,441 --> 00:39:22,751 Everything's fine. We're finished. The procedure is done. 436 00:39:23,186 --> 00:39:28,888 Do you feel anything? 437 00:39:37,200 --> 00:39:38,941 I'm sorry, Henry. 438 00:39:48,429 --> 00:39:51,040 [DISTANT VOICES CAN BE HEARD] 439 00:40:02,008 --> 00:40:03,792 [GASPS] 440 00:40:05,794 --> 00:40:13,280 [PHONE BUZZING] 441 00:40:18,894 --> 00:40:21,027 It's Eddie. I'm out. 442 00:40:22,463 --> 00:40:24,596 Now's not a very good time. 443 00:40:24,639 --> 00:40:30,950 Did you hear what I said? I need you. Hello? 444 00:40:33,082 --> 00:40:34,736 I'll be there in a of couple days. 445 00:40:34,780 --> 00:40:37,217 A couple-- 446 00:40:38,523 --> 00:40:42,048 [LOW FREQUENCY DRONE SOUND] 447 00:40:45,704 --> 00:40:50,317 ♪PIANO MUSIC OVERLAPS DRONE 448 00:41:12,513 --> 00:41:13,166 Henry? 449 00:41:13,209 --> 00:41:14,733 I need stem cells. 450 00:41:14,776 --> 00:41:17,083 I'm with a patient. 451 00:41:17,126 --> 00:41:18,998 If I can find a way to convert them into nociceptors-- 452 00:41:19,041 --> 00:41:22,523 You can't just barge in here like this. 453 00:41:22,567 --> 00:41:24,307 You have gout. 454 00:41:24,351 --> 00:41:26,353 It's acute inflammatory arthritis at the base of your 455 00:41:26,396 --> 00:41:27,876 big toe. Take some Diclofenac 456 00:41:27,920 --> 00:41:29,661 and stop eating foods with such high levels of purines. 457 00:41:29,704 --> 00:41:32,011 I'm sorry. Would you excuse me for a minute? 458 00:41:38,234 --> 00:41:40,193 What the hell are you thinking? 459 00:41:40,236 --> 00:41:41,542 They have to be embryonic. 460 00:41:41,586 --> 00:41:43,936 Henry, you can't keep doing this. 461 00:41:43,979 --> 00:41:45,546 Look, Thebaine was a mistake, okay? 462 00:41:45,590 --> 00:41:48,114 It was my miscalculation. This can actually work! 463 00:41:48,157 --> 00:41:51,247 Enough! Even if it was possible that what you're 464 00:41:51,291 --> 00:41:52,510 saying would work-- 465 00:41:52,553 --> 00:41:55,469 -It is. -Which is highly unlikely-- 466 00:41:55,513 --> 00:41:58,690 and you got your hands on embryonic stem cells, which 467 00:41:58,733 --> 00:42:01,649 you can't, which hardly anybody can, it would probably take 468 00:42:01,693 --> 00:42:06,436 years to establish a stable cell line. Let alone the millions of 469 00:42:06,480 --> 00:42:08,830 dollars for specialized equipment that you don't have 470 00:42:08,874 --> 00:42:10,136 access to. 471 00:42:10,179 --> 00:42:13,705 -I can get access. -Where? 472 00:42:18,536 --> 00:42:21,495 Jesus Christ. Andrews. 473 00:42:21,539 --> 00:42:24,324 He just did a couple of tests. I mean, it's no big deal. 474 00:42:24,367 --> 00:42:27,196 Everything is a big deal with him. 475 00:42:30,591 --> 00:42:33,855 What is it with you two anyway? 476 00:42:35,204 --> 00:42:40,340 He was my research partner 20 years ago. 477 00:42:40,819 --> 00:42:43,517 We were experimenting with a drug that was designed to help 478 00:42:43,561 --> 00:42:45,127 alleviate chronic pain. 479 00:42:45,171 --> 00:42:49,175 We were coming up with great results, and we got approval for 480 00:42:49,218 --> 00:42:51,743 clinical trials with humans. 481 00:42:51,786 --> 00:42:55,877 We thought we were on the verge of a major breakthrough. 482 00:42:55,921 --> 00:42:58,358 Okay. What happened? 483 00:42:58,401 --> 00:43:00,316 We just weren't getting the results we wanted, 484 00:43:00,360 --> 00:43:08,847 and Andrews was convinced that we needed to up the dosages, 485 00:43:08,890 --> 00:43:11,676 way above protocol. 486 00:43:12,024 --> 00:43:17,986 Eventually we did, and I should have stopped him. 487 00:43:18,030 --> 00:43:21,990 But he kept telling me that I was too scared to take risks, 488 00:43:22,034 --> 00:43:26,125 that I wasn't committed, and meanwhile, a number of the 489 00:43:26,168 --> 00:43:30,825 subjects developed tumors. 490 00:43:31,913 --> 00:43:36,048 Five people lost their lives. 491 00:43:39,051 --> 00:43:45,100 Henry, you have to understand Andrews is obsessed. 492 00:43:45,144 --> 00:43:49,670 He will stop at nothing to get the results he wants. 493 00:43:49,714 --> 00:43:56,111 I'm begging you, let go of this madness before it's too late. 494 00:44:06,861 --> 00:44:10,430 [KNOCKING ON DOOR] 495 00:44:12,911 --> 00:44:16,392 What the hell happened to you? 496 00:44:17,393 --> 00:44:20,353 Oh, I knew you would come through for us, Henry. 497 00:44:27,273 --> 00:44:29,057 We need to talk. 498 00:44:29,101 --> 00:44:31,669 I need to talk to you too. 499 00:44:31,712 --> 00:44:33,671 Remember that guy I was telling you about? 500 00:44:33,714 --> 00:44:35,020 He's well connected. 501 00:44:35,063 --> 00:44:36,630 The drug dealer? 502 00:44:36,674 --> 00:44:37,326 Yeah. 503 00:44:37,718 --> 00:44:39,241 What about him? 504 00:44:39,285 --> 00:44:40,547 I met with him. 505 00:44:42,114 --> 00:44:45,030 -He wants to partner with us. -Did you tell him about me? 506 00:44:45,073 --> 00:44:47,293 I just told him that I had to speak to my partner. 507 00:44:48,816 --> 00:44:50,949 I didn't want to leave you out. 508 00:45:02,787 --> 00:45:05,964 I don't want to do this anymore. 509 00:45:10,359 --> 00:45:11,534 Henry -- 510 00:45:13,362 --> 00:45:17,279 [UPBEAT PIANO POP MUSIC] 511 00:45:41,173 --> 00:45:42,609 Hi. 512 00:45:43,436 --> 00:45:45,307 Hey. 513 00:45:47,657 --> 00:45:51,618 Do you want to go for a ride? 514 00:45:54,795 --> 00:45:56,318 Yeah. 515 00:46:02,455 --> 00:46:05,893 You drive. 516 00:46:51,330 --> 00:46:56,204 There is something that I -- I want to tell you that I 517 00:46:56,248 --> 00:46:59,773 haven't told anyone else in a very long time. 518 00:47:02,254 --> 00:47:06,867 I have this condition where I don't feel pain. 519 00:47:06,911 --> 00:47:11,829 I can't feel pain. I feel everything else. 520 00:47:11,872 --> 00:47:15,615 Just not that. 521 00:47:19,053 --> 00:47:20,620 The ice? 522 00:47:21,969 --> 00:47:27,845 Yeah, right. I, um, have a hard time distinguishing hot 523 00:47:27,888 --> 00:47:31,849 or cold and I've kind of hurt myself badly before so -- 524 00:47:33,589 --> 00:47:38,377 I live my life kind of separate from other people because I'm 525 00:47:38,420 --> 00:47:44,339 not like other people, and you meet someone like you, and it 526 00:47:44,383 --> 00:47:48,256 just kind of reminds you that, um -- 527 00:47:49,214 --> 00:47:51,172 Reminds you of what? 528 00:47:54,349 --> 00:47:56,656 That you're alive. 529 00:47:58,919 --> 00:48:02,705 I've spent my whole life trying to fix myself. 530 00:48:04,969 --> 00:48:09,669 Now I'm starting to think maybe that's not the way to go, 531 00:48:09,712 --> 00:48:12,237 you know? 532 00:48:14,717 --> 00:48:16,110 What do you think? 533 00:48:18,156 --> 00:48:23,074 I think life is short and you have to do what makes you happy. 534 00:48:23,117 --> 00:48:25,641 Fuck the rest. 535 00:48:28,296 --> 00:48:30,820 Okay. I like that. 536 00:48:54,583 --> 00:48:55,933 Friends of yours? 537 00:48:55,976 --> 00:48:57,630 Those are actually very special mice. 538 00:48:57,673 --> 00:49:01,939 Um, they're genetically altered. 539 00:49:01,982 --> 00:49:03,070 Altered? 540 00:49:03,114 --> 00:49:07,640 Mm-hmm. They're, um, they're like me. 541 00:49:08,380 --> 00:49:10,643 Yeah? Just like you, huh? 542 00:49:10,686 --> 00:49:15,169 No. Um, those --those guys are assholes. 543 00:49:15,213 --> 00:49:18,390 Um, do you want to see these? 544 00:49:18,433 --> 00:49:19,695 Yeah, can I? Can I hold them? 545 00:49:19,739 --> 00:49:21,784 Yeah. Yeah. Um -- 546 00:49:22,481 --> 00:49:23,917 -Are -- do I need gloves? -I -- I put on the gloves 547 00:49:23,961 --> 00:49:26,659 just 'cause I -- I, um, I wouldn't feel if they were 548 00:49:26,702 --> 00:49:28,791 biting or scratching. Not that they will. 549 00:49:28,835 --> 00:49:31,359 They wouldn't. It's an old habit. 550 00:49:31,403 --> 00:49:33,274 Hey. 551 00:49:37,409 --> 00:49:39,237 They're not used to other people. 552 00:49:40,238 --> 00:49:42,370 You don't have a lot of visitors? 553 00:49:42,414 --> 00:49:49,987 Um, not especially. No. She likes you though. 554 00:49:56,863 --> 00:49:58,125 Shh, it's okay. It's okay. 555 00:49:58,169 --> 00:49:59,518 Thanks for letting me say hi to your friend. 556 00:49:59,561 --> 00:50:05,045 No problem. Go down, sweetheart. Shh. 557 00:50:05,089 --> 00:50:06,525 And this: 558 00:50:07,526 --> 00:50:09,658 Oh, I use the peppers to make the extract, and then 559 00:50:09,702 --> 00:50:13,923 that's how I test them for the pain. Yeah. 560 00:50:13,967 --> 00:50:16,317 Chile peppers. 561 00:50:17,449 --> 00:50:20,191 You know, Henry, for someone who doesn't feel pain, you sure know 562 00:50:20,234 --> 00:50:22,628 an awful lot about it. 563 00:50:23,890 --> 00:50:28,721 Yeah. I mean, I, uh, I mean, I've spent my whole life 564 00:50:28,764 --> 00:50:32,551 thinking about it, you know? I -- I've taught myself how to see 565 00:50:32,594 --> 00:50:36,294 it in others. It always amazes me, like, people walk around 566 00:50:36,337 --> 00:50:41,125 with so much pain. Like, take you for example. Like, I know 567 00:50:41,168 --> 00:50:43,605 you think you have pain in your shoulder, and I know this sounds 568 00:50:43,649 --> 00:50:45,520 funny, but actually it's referred from a completely 569 00:50:45,564 --> 00:50:47,479 different area, and you don't have a problem here at all. 570 00:50:47,522 --> 00:50:50,438 It's-- it's -- it's the surrounding muscle groups. 571 00:51:07,368 --> 00:51:12,330 ♪LIGHT GUITAR STRUMMING MUSIC PLAYS♪ 572 00:51:15,289 --> 00:51:20,120 ♪HOLD ME, AND GUIDE ME 573 00:51:20,164 --> 00:51:22,775 You can live your whole life trying to change. 574 00:51:22,818 --> 00:51:25,212 Trying to be something you're not. 575 00:51:29,216 --> 00:51:31,653 Telling yourself it's okay to be alone. 576 00:51:34,265 --> 00:51:36,919 That simply surviving is enough. 577 00:51:38,704 --> 00:51:43,056 [PHONE BUZZING] 578 00:51:43,535 --> 00:51:51,108 ♪OH REMIND ME HOW YOU COULD FIND-- ♪ 579 00:51:51,151 --> 00:51:54,111 And then one day everything changes. 580 00:51:57,201 --> 00:52:00,465 ♪GUITAR MUSIC STRUMS 581 00:52:00,508 --> 00:52:04,599 ♪OOOOOOOO 582 00:52:12,564 --> 00:52:14,348 Hello, Henry. 583 00:52:16,872 --> 00:52:18,091 Why are you here? 584 00:52:18,396 --> 00:52:20,789 It didn't work, did it? The Thebaine? 585 00:52:20,833 --> 00:52:22,661 We knew it was a long shot. 586 00:52:22,704 --> 00:52:23,879 What do you want? 587 00:52:25,403 --> 00:52:27,144 This whole time you've been focused on increasing the 588 00:52:27,187 --> 00:52:29,798 effectiveness of Naloxone derivatives, correct? 589 00:52:29,842 --> 00:52:32,540 Has it ever occurred to you to ask why it's only effective in 590 00:52:32,584 --> 00:52:35,456 such a small percentage of the population to begin with? 591 00:52:35,500 --> 00:52:38,155 Naloxone binds to opiate receptors. 592 00:52:38,198 --> 00:52:40,287 People with my condition have more than most. 593 00:52:40,331 --> 00:52:43,160 Based on the theory that the cause is due to a mutation of 594 00:52:43,203 --> 00:52:44,161 the NTRK1 gene. 595 00:52:44,204 --> 00:52:45,597 Are you here for a fact check? 596 00:52:45,640 --> 00:52:48,034 What if it weren't? 597 00:52:48,077 --> 00:52:52,038 What if there were another gene with a similar mutation? 598 00:52:52,081 --> 00:52:55,172 Think about it. It would explain why Naloxone is 599 00:52:55,215 --> 00:52:57,043 only effective in such a small group. 600 00:52:58,218 --> 00:53:02,483 Every experiment failed. It was bad science, okay? 601 00:53:02,527 --> 00:53:04,659 It was my fault. Everything failed. 602 00:53:04,703 --> 00:53:06,357 So you get up and you try again! That's what we -- 603 00:53:06,400 --> 00:53:10,187 You're not listening to me. It's not science fiction. 604 00:53:10,230 --> 00:53:13,015 -It's my life. -It's all science fiction until 605 00:53:13,059 --> 00:53:15,322 we prove it otherwise. That's what it means 606 00:53:15,366 --> 00:53:17,194 to be on the cutting edge of discovery. 607 00:53:18,891 --> 00:53:24,679 I spoke to Ray. Five people died. 608 00:53:24,723 --> 00:53:26,855 What were they? A good candidate? 609 00:53:26,899 --> 00:53:29,293 A good subject? A science experiment? 610 00:53:29,336 --> 00:53:31,860 Do you have no remorse at all? 611 00:53:31,904 --> 00:53:34,602 Yes. I've made mistakes. I admit. 612 00:53:36,169 --> 00:53:39,216 At least I'm not afraid of taking risks. 613 00:53:39,259 --> 00:53:41,348 And frankly, so what, huh? 614 00:53:41,392 --> 00:53:45,874 So what if some people got hurt? We're -- we're talking about 615 00:53:45,918 --> 00:53:49,400 profound scientific discovery. Don't be naive. That's the cost 616 00:53:49,443 --> 00:53:50,836 of doing business. 617 00:53:50,879 --> 00:53:53,447 The cost of doing business? 618 00:53:59,671 --> 00:54:01,020 I can give you what you want, Henry. 619 00:54:01,063 --> 00:54:03,631 Yeah? What's that? 620 00:54:03,675 --> 00:54:05,416 Pain. 621 00:54:14,381 --> 00:54:18,255 ♪LIGHT ROCK GUITAR PLAYS 622 00:54:34,532 --> 00:54:36,403 Something on your mind? 623 00:54:38,797 --> 00:54:41,060 I just feel good, you know? 624 00:54:44,455 --> 00:54:49,024 There's just so much that I want to do now. 625 00:54:50,330 --> 00:54:51,897 Like what? 626 00:54:52,506 --> 00:54:54,639 Like ice-skating. 627 00:54:58,077 --> 00:55:00,645 I've just never been. 628 00:55:03,343 --> 00:55:05,214 I think we can arrange that. 629 00:55:11,351 --> 00:55:12,309 RON: Shani? 630 00:55:12,352 --> 00:55:13,614 Ron. 631 00:55:13,658 --> 00:55:18,880 Hey. I thought that was you. You look nice. 632 00:55:18,924 --> 00:55:20,229 What are you doing here? 633 00:55:20,273 --> 00:55:22,623 Uh, having dinner with a friend. This is Ron. 634 00:55:22,667 --> 00:55:24,408 He, uh, used to work at the cafe. 635 00:55:24,451 --> 00:55:27,976 God, you look nice. I miss those days. Hey, I'm having a 636 00:55:28,020 --> 00:55:29,674 drink over at the bar. You want to come join me? 637 00:55:29,717 --> 00:55:30,675 Maybe another time. 638 00:55:30,718 --> 00:55:32,807 Come on. I'll buy you a shot. 639 00:55:32,851 --> 00:55:34,331 No thanks. 640 00:55:34,374 --> 00:55:37,508 It's fine. If you want to grab a quick drink, I don't -- 641 00:55:37,551 --> 00:55:40,772 Look, I appreciate the offer, but I'd rather just 642 00:55:40,815 --> 00:55:42,991 be alone. 643 00:55:46,691 --> 00:55:48,040 You're serious? 644 00:55:48,823 --> 00:55:50,390 Why are you being like this? 645 00:55:50,434 --> 00:55:51,478 Being like what? 646 00:55:51,522 --> 00:55:52,784 -A dick. -Hey, you're the one with 647 00:55:52,827 --> 00:55:54,525 the stick up her ass. -Excuse me? 648 00:55:54,568 --> 00:55:57,919 Hold on there. 649 00:55:57,963 --> 00:56:00,661 You got something you want to say to me? 650 00:56:00,705 --> 00:56:02,576 I do actually. 651 00:56:02,620 --> 00:56:04,099 -Oh, yeah? And what is that? -It's fine. 652 00:56:04,143 --> 00:56:09,278 It's not fine. You're being rude to my friend. 653 00:56:09,322 --> 00:56:14,458 That's not okay. You owe her an apology. 654 00:56:16,938 --> 00:56:21,378 Your friend's a little cock tease. 655 00:56:21,421 --> 00:56:22,509 -Hey! -Got something to say to me 656 00:56:22,553 --> 00:56:24,337 now? 657 00:56:36,741 --> 00:56:39,221 Henry! 658 00:56:41,441 --> 00:56:43,443 Henry! 659 00:56:45,097 --> 00:56:46,794 Asshole. 660 00:56:49,101 --> 00:56:53,845 Henry! Henry! 661 00:56:55,716 --> 00:57:00,373 Come on, wait. That guy, he was being an asshole. 662 00:57:00,417 --> 00:57:03,028 Look, I'm sorry. It was a mistake, okay? 663 00:57:03,071 --> 00:57:04,595 What? 664 00:57:04,638 --> 00:57:08,729 No. I--I gotta go. Just--just please leave me alone, okay? 665 00:57:08,773 --> 00:57:11,558 But Henry -- 666 00:57:14,866 --> 00:57:17,999 RECORDING: Stand clear of the closing doors, please. 667 00:57:27,400 --> 00:57:33,014 ♪LIGHT PIANO MUSIC PLAYS 668 00:57:53,295 --> 00:57:57,125 ♪PIANO MUSIC CONTINUES 669 00:58:01,521 --> 00:58:04,611 [PHONE BUZZING] 670 00:58:17,363 --> 00:58:22,063 ♪MUSIC INTENSIFIES AND BECOMES LOUD HUMMING♪ 671 00:59:29,870 --> 00:59:35,006 ♪LIGHT HUMMING AND UPBEAT MUSIC BEGINS♪ 672 00:59:43,710 --> 00:59:49,020 ♪MUSIC INTENSIFIES WITH BEATS 673 01:00:02,642 --> 01:00:09,475 ♪MUSIC INTENSIFIES WITH DRUMS 674 01:00:34,718 --> 01:00:38,460 ♪TECHNO LIKE MUSIC CONTINUES 675 01:00:51,517 --> 01:00:53,475 We need to do a gene test. 676 01:00:56,870 --> 01:00:59,133 Okay. 677 01:01:00,395 --> 01:01:04,530 ♪MELANCHOLY BEATS BEGIN 678 01:01:35,517 --> 01:01:37,128 You were right. 679 01:01:38,390 --> 01:01:41,088 It is a mutation of the SCN9A. 680 01:01:43,395 --> 01:01:46,528 The problem is with your sodium channels. 681 01:01:46,572 --> 01:01:48,661 I'll be damned. 682 01:01:53,448 --> 01:01:55,799 This is groundbreaking. 683 01:01:57,975 --> 01:02:00,325 I know what we have to do. 684 01:02:00,934 --> 01:02:03,763 I can't do it alone. 685 01:02:04,764 --> 01:02:07,071 You can do any tests you want. 686 01:02:12,554 --> 01:02:15,079 Yes. Of course. We'll do it together. 687 01:02:17,690 --> 01:02:22,739 ♪MELANCHOLY MUSIC BEGINS 688 01:02:22,782 --> 01:02:25,437 We can use gene therapy to replace the faulty gene with 689 01:02:25,480 --> 01:02:28,048 a proper one. 690 01:02:32,444 --> 01:02:34,576 Inducing your nerve cells to create normally 691 01:02:34,620 --> 01:02:37,362 functioning sodium channels so they can properly transmit your 692 01:02:37,405 --> 01:02:39,451 pain signals. 693 01:02:39,494 --> 01:02:41,627 We'll just need to select a viral vector to deliver the 694 01:02:41,670 --> 01:02:43,194 gene. 695 01:02:43,803 --> 01:02:47,676 Take the normal functioning SCN9A gene and deliver it to the 696 01:02:47,720 --> 01:02:49,374 cells. 697 01:02:49,417 --> 01:02:54,205 We let the healthy cells fix the problem for us. 698 01:02:54,248 --> 01:02:59,297 That's really good. We could have a sample soon. 699 01:03:02,822 --> 01:03:06,043 [KNOCKING ON DOOR] 700 01:03:41,861 --> 01:03:43,428 Are you okay? 701 01:03:50,870 --> 01:03:54,265 Henry, you're scaring me. 702 01:03:56,528 --> 01:03:58,617 I'm working. 703 01:03:59,531 --> 01:04:01,838 This isn't who you are. 704 01:04:06,886 --> 01:04:10,585 You're wrong. This is exactly who I am. 705 01:04:14,589 --> 01:04:15,982 It doesn't have to be. 706 01:04:16,026 --> 01:04:23,337 But that's the point. It does. It does. It was just -- 707 01:04:23,381 --> 01:04:27,124 it wasn't real. It was -- it was just a bad fantasy. 708 01:04:33,521 --> 01:04:37,830 Can you look at me? Henry? 709 01:05:11,646 --> 01:05:14,606 I'm sorry. I'm so sorry. 710 01:05:14,649 --> 01:05:17,783 I just don't have time for distractions. 711 01:05:23,484 --> 01:05:26,705 I'm really sorry. 712 01:05:29,447 --> 01:05:34,234 You gotta go now. 713 01:05:53,993 --> 01:05:55,038 Is the sample ready? 714 01:05:56,474 --> 01:05:57,736 Yes. 715 01:05:58,258 --> 01:06:00,739 I need you to give it to me. 716 01:06:00,782 --> 01:06:02,262 What for? 717 01:06:02,306 --> 01:06:03,524 I -- I don't have to time to talk about it right now. 718 01:06:03,568 --> 01:06:04,961 I just need you to give it to me. 719 01:06:05,004 --> 01:06:07,659 I'm not going to give you the sample, Henry. 720 01:06:10,923 --> 01:06:12,490 What are you doing? 721 01:06:12,533 --> 01:06:13,839 Where is it? 722 01:06:13,882 --> 01:06:15,319 What would you do with it if I let you have it? 723 01:06:15,362 --> 01:06:16,929 That's none of your concern. 724 01:06:16,973 --> 01:06:19,018 It is if you're planning on doing something stupid with it. 725 01:06:19,062 --> 01:06:21,107 Give me my sample. 726 01:06:22,761 --> 01:06:25,938 Give me my fucking sample! I discovered this! 727 01:06:25,982 --> 01:06:30,116 That's enough! Do you realize we're on the verge 728 01:06:30,160 --> 01:06:33,511 of a major breakthrough? We have a long way to go before we're 729 01:06:33,554 --> 01:06:38,124 ready for clinical trials in humans. Can you not see that? 730 01:06:38,168 --> 01:06:41,258 Do you realize what's at stake? 731 01:06:44,870 --> 01:06:47,786 [LOW AMBIENCE] 732 01:07:00,886 --> 01:07:04,585 [MYSTERIOUS AMBIENCE FILLS THE SCREEN] 733 01:07:17,120 --> 01:07:21,037 [MYSTERIOUS DRAMATIC AMBIENCE INTENSIFIES] 734 01:07:57,812 --> 01:08:00,902 [MYSTERIOUS DRAMATIC AMBIENCE CONTINUES] 735 01:08:11,130 --> 01:08:13,828 [KNOCKING AT DOOR] 736 01:08:24,187 --> 01:08:26,754 Hey. 737 01:08:30,541 --> 01:08:35,154 What the hell's going on? 738 01:08:35,198 --> 01:08:38,375 Henry? Your phone's off. You haven't been keeping 739 01:08:38,418 --> 01:08:39,941 your appointments. 740 01:08:43,031 --> 01:08:45,251 I've been working. 741 01:08:45,295 --> 01:08:47,384 Yeah. 742 01:08:48,167 --> 01:08:49,908 Take a look. 743 01:08:54,652 --> 01:08:58,873 I did it, Ray. I -- I solved it. 744 01:09:05,793 --> 01:09:09,971 SCN9A? What makes you think-- 745 01:09:10,015 --> 01:09:11,625 Tests confirmed it. 746 01:09:11,669 --> 01:09:12,800 No, it's -- 747 01:09:12,844 --> 01:09:14,106 It's beautiful, isn't it? 748 01:09:14,150 --> 01:09:16,152 It's a nice theory. 749 01:09:17,762 --> 01:09:19,198 A theory? 750 01:09:19,242 --> 01:09:20,808 Yeah. What would you call it? 751 01:09:20,852 --> 01:09:23,246 I'd call it the thing I've been waiting for my entire life. 752 01:09:23,289 --> 01:09:27,511 You don't know that. This will take years of testing. 753 01:09:27,554 --> 01:09:29,861 I don't have time for that. 754 01:09:32,298 --> 01:09:33,778 Have you lost your mind? 755 01:09:33,821 --> 01:09:36,259 No! I cured a fucking disease! 756 01:09:36,302 --> 01:09:38,870 You don't have proof of that. 757 01:09:38,913 --> 01:09:40,872 This is all theoretical. 758 01:09:40,915 --> 01:09:42,743 Even if it worked, you don't know what the 759 01:09:42,787 --> 01:09:46,878 long-term side effects would be. You need preclinical data, 760 01:09:46,921 --> 01:09:48,227 clinical trials. 761 01:09:48,271 --> 01:09:50,142 You're just jealous. 762 01:09:50,186 --> 01:09:52,057 -What? -Just because you didn't 763 01:09:52,100 --> 01:09:55,365 have the guts to finish your work doesn't mean I don't have 764 01:09:55,408 --> 01:09:59,586 the guts to finish mine. 765 01:09:59,630 --> 01:10:04,069 Injecting untested genes isn't science. 766 01:10:04,112 --> 01:10:06,637 It's suicide! 767 01:10:07,899 --> 01:10:14,645 Henry, life is not just a distraction. This is. 768 01:10:14,688 --> 01:10:19,345 What do you know about it? What do you know about it? 769 01:10:19,389 --> 01:10:21,956 What do you know about living everyday like it might be your 770 01:10:22,000 --> 01:10:24,307 last, and you don't even know if you care anymore? What do you 771 01:10:24,350 --> 01:10:28,136 know about never feeling normal? 772 01:10:29,747 --> 01:10:35,927 I don't know. But what I do know is this isn't the answer. 773 01:10:35,970 --> 01:10:38,146 I'm trying to protect you. 774 01:10:38,190 --> 01:10:42,760 I don't need protection, I need results! 775 01:10:42,803 --> 01:10:45,545 -At what cost? -At any fucking cost. 776 01:10:49,680 --> 01:10:52,813 [LIGHT MELANCHOLY PIANO MUSIC] 777 01:10:54,598 --> 01:10:59,255 Henry. Henry, please. 778 01:10:59,298 --> 01:11:03,563 I think it's time for you to go. 779 01:11:12,355 --> 01:11:15,967 ♪LIGHT PIANO MUSIC PLAYS 780 01:11:39,033 --> 01:11:43,037 ♪PIANO MUSIC INTENSIFIES AND CONTINUES♪ 781 01:12:31,782 --> 01:12:37,222 Henry. Oh, thank God. I was worried sick. 782 01:12:44,447 --> 01:12:48,320 Well, did it work? 783 01:12:48,364 --> 01:12:50,235 I don't know. I didn't do it. 784 01:12:51,410 --> 01:12:53,717 What? Why? 785 01:12:53,760 --> 01:13:00,376 I guess I realized that if I did it, and it didn't work, 786 01:13:00,419 --> 01:13:05,685 I mean, if I died in that room, no one would even notice. 787 01:13:05,729 --> 01:13:12,866 I mean, it would be like I was never even born. I just -- 788 01:13:12,910 --> 01:13:15,086 I can't do this anymore. 789 01:13:18,045 --> 01:13:21,788 Well, you can't just walk away from this. 790 01:13:21,832 --> 01:13:24,269 -Look at how far we've come. -It's my decision. 791 01:13:24,312 --> 01:13:27,403 Oh, the hell it is! We're talking about controlling 792 01:13:27,446 --> 01:13:31,015 pain at a genetic level. That's never been done before! 793 01:13:31,058 --> 01:13:34,584 Can't you see what's at stake for us? 794 01:13:34,627 --> 01:13:35,889 For "us?" 795 01:13:35,933 --> 01:13:36,977 Yes, for us. 796 01:13:37,021 --> 01:13:39,458 I'm the one taking all the risks. 797 01:13:40,285 --> 01:13:42,548 This is my life's work. What gives you the right to be so 798 01:13:42,592 --> 01:13:44,245 selfish? 799 01:13:49,729 --> 01:13:51,905 Did you want me to steal that? 800 01:13:51,949 --> 01:13:54,168 Oh, that's preposterous. 801 01:13:54,212 --> 01:13:57,128 You knew. You knew that I would never wait for proper 802 01:13:57,171 --> 01:14:02,916 testing, and you couldn't take another scandal. Am I right? 803 01:14:02,960 --> 01:14:06,442 You didn't want any more blood on your hands, right? 804 01:14:06,485 --> 01:14:07,921 Am I right? 805 01:14:11,969 --> 01:14:13,884 Patience isn't either of our strong suit, and I 806 01:14:13,927 --> 01:14:18,628 knew -- I knew it was only a matter of time before you became 807 01:14:18,671 --> 01:14:20,673 desperate enough. 808 01:14:22,675 --> 01:14:24,416 And with the only way for me to know the true 809 01:14:24,460 --> 01:14:27,463 potential for this type of gene therapy on my sodium channels 810 01:14:27,506 --> 01:14:29,290 would be to understand how it affects yours. 811 01:14:29,334 --> 01:14:33,860 And what would've happened if it didn't work and I died? 812 01:14:35,079 --> 01:14:36,602 It was your decision to make. 813 01:14:36,646 --> 01:14:39,126 Do you care about anyone but yourself? 814 01:14:39,170 --> 01:14:42,782 How can you say that? I care about everyone! 815 01:14:42,826 --> 01:14:46,699 Don't you see that's what all this is about? 816 01:14:46,743 --> 01:14:49,572 I'm done. It's over. 817 01:14:49,615 --> 01:14:50,877 That is your fear talking. 818 01:14:50,921 --> 01:14:53,140 No. It's yours. 819 01:14:53,184 --> 01:14:57,231 Where are you going? There's nothing out there for you. 820 01:15:00,539 --> 01:15:02,933 We'll see. 821 01:15:02,976 --> 01:15:09,113 Henry, you -- don't go! Henry! I need you! 822 01:15:09,156 --> 01:15:13,683 That's what you want to hear? Henry, please! 823 01:15:14,901 --> 01:15:18,035 [INTENSIFIED DRONE SOUNDS] 824 01:15:49,719 --> 01:15:55,115 [LIGHT SUSPENSEFUL AMBIENCE] 825 01:16:29,802 --> 01:16:32,544 [LIGHT AIRY AMBIENCE CONTINUES] 826 01:16:41,379 --> 01:16:45,775 I've spent my whole life afraid of taking risks. 827 01:16:45,818 --> 01:16:53,086 Trying to change who I am. You showed me I can do more. 828 01:16:56,655 --> 01:16:57,787 Goodnight, Paulina. 829 01:16:57,830 --> 01:17:02,269 Oh, this came for you earlier. 830 01:17:06,056 --> 01:17:10,408 So I've decided to leave this city for a while. 831 01:17:12,279 --> 01:17:16,022 There's a hospital in a place that I've never been and 832 01:17:16,066 --> 01:17:19,286 apparently they can use my help. 833 01:17:25,423 --> 01:17:28,339 Is everything okay? 834 01:17:28,382 --> 01:17:32,604 Yeah. I'll see you tomorrow. 835 01:17:32,648 --> 01:17:34,301 Good night. 836 01:17:34,345 --> 01:17:36,216 I don't know what's out there for me. 837 01:17:36,260 --> 01:17:38,305 I don't know what lays ahead. 838 01:17:38,349 --> 01:17:41,700 But I do know I need to find out. 839 01:17:43,920 --> 01:17:51,884 It's like you said: "Do what makes you happy. Fuck the rest." 840 01:17:51,928 --> 01:17:56,933 ♪UPLIFTING PIANO MUSIC FADES OUT♪ 62511

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