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1
00:00:00,001 --> 00:00:05,384
Victim is Mr Arnie Rahul.
Consultant surgeon. 48 years of age.
2
00:00:05,387 --> 00:00:08,215
Good reputation, though he's fallen
out with a few people recently.
3
00:00:08,218 --> 00:00:10,817
{\an8}He was about to start an operation.
He gets a phone call.
4
00:00:10,820 --> 00:00:13,050
Walks out, never comes back.
5
00:00:13,053 --> 00:00:16,090
Single puncture wound to
the left chest wall.
6
00:00:17,290 --> 00:00:20,088
What's that in his hand?
Looks like a syringe and needle.
7
00:00:20,090 --> 00:00:23,328
It's a Hickman line.
A long-term vascular access device
8
00:00:23,330 --> 00:00:25,848
for people who need chemotherapy
or blood transfusions.
9
00:00:25,850 --> 00:00:28,568
The assailant would have had
extensive cross contamination
10
00:00:28,570 --> 00:00:30,048
with the victim's blood.
11
00:00:30,050 --> 00:00:32,208
Stick that in to a big artery
and blood will flow out
12
00:00:32,210 --> 00:00:33,768
like a high-pressure hose.
13
00:00:33,770 --> 00:00:35,130
Simi Jacobs.
14
00:00:36,210 --> 00:00:37,570
He's denying everything.
15
00:00:38,650 --> 00:00:41,888
Simi Jacobs is not a match
16
00:00:41,890 --> 00:00:43,528
to the blood spatter at the scene.
17
00:00:43,530 --> 00:00:45,808
So, who is it? It's Wilfred Okoye.
18
00:00:45,810 --> 00:00:46,928
The patient?
19
00:00:46,930 --> 00:00:50,688
Arnie Rahul was murdered by a man
who was under general anaesthetic
20
00:00:50,690 --> 00:00:52,088
in a different room?
21
00:00:52,090 --> 00:00:55,728
Blood alcohol level, three times
the legal driving limit.
22
00:00:55,730 --> 00:00:58,048
You said he shouldn't be operating.
23
00:00:58,050 --> 00:01:00,048
Not after the Harry Fletcher
incident.
24
00:01:00,050 --> 00:01:02,968
Arrested on the table
during surgery last week.
25
00:01:02,970 --> 00:01:05,608
I want you to do the postmortem.
26
00:01:05,610 --> 00:01:07,808
Technically that would be
a conflict of interest.
27
00:01:07,810 --> 00:01:11,088
Summarising postmortem examination,
Harry Fletcher.
28
00:01:11,090 --> 00:01:13,008
What are you doing?
My colleagues are here.
29
00:01:13,010 --> 00:01:15,968
Is that Emily Braithwaite?
She's Adam's godmother.
30
00:01:15,970 --> 00:01:18,088
You'd think he might have
mentioned it.
31
00:01:18,090 --> 00:01:20,608
Are you going to confront him?
Not yet.
32
00:01:20,610 --> 00:01:23,048
Your original stem cell work
was brilliant.
33
00:01:23,050 --> 00:01:26,928
But you tried and failed to turn
it into a viable cancer treatment.
34
00:01:26,930 --> 00:01:29,488
Wilfred Okoye, still in
the hospital.
35
00:01:29,490 --> 00:01:31,168
What's he going to know?
36
00:01:31,170 --> 00:01:34,128
You won't find out unless you
ask him.
37
00:01:34,130 --> 00:01:37,008
Mr Fletcher died because of
surgical error.
38
00:01:37,010 --> 00:01:40,568
Adam! You have no idea what
you've done.
39
00:01:40,570 --> 00:01:43,088
When I applied for this job
I falsified my CV,
40
00:01:43,090 --> 00:01:44,968
and Emily Braithwaite tried to
use this
41
00:01:44,970 --> 00:01:47,248
fact to influence my findings in
the Fletcher Case.
42
00:01:47,250 --> 00:01:48,928
Here's my letter of resignation.
43
00:01:48,930 --> 00:01:50,210
Effective immediately.
44
00:01:51,730 --> 00:01:57,770
{\an8}# Testator silens
45
00:02:00,290 --> 00:02:07,448
# Costestes e spiritu
46
00:02:07,450 --> 00:02:14,930
# Silencium
47
00:02:22,250 --> 00:02:28,050
# Testator silens. #
48
00:02:34,170 --> 00:02:36,770
DISTANT SIREN
49
00:02:39,570 --> 00:02:43,128
Wilfred Okoye, a Beninese
farm worker, was admitted
50
00:02:43,130 --> 00:02:47,288
to St Jude's hospital for the
treatment of leukaemia a week ago.
51
00:02:47,290 --> 00:02:50,688
Although he lost consciousness
briefly during the attack
52
00:02:50,690 --> 00:02:54,368
on his life last night, he seems to
have recovered with no ill effects.
53
00:02:54,370 --> 00:02:58,688
Awaiting toxicology from the syringe
we believe was used in the attack.
54
00:02:58,690 --> 00:03:00,448
Prints? Fibres?
55
00:03:00,450 --> 00:03:02,728
Nothing conclusive.
We're interviewing witnesses
56
00:03:02,730 --> 00:03:04,888
but no-one got a good look at
the attacker.
57
00:03:04,890 --> 00:03:07,408
How come he's being treated here
in the UK?
58
00:03:07,410 --> 00:03:11,250
It was set up by a charity,
and then arranged through Rahul.
59
00:03:12,850 --> 00:03:17,088
Here is a man who has lived his
entire life in Benin
60
00:03:17,090 --> 00:03:21,288
up until a week ago, and,
according to our DNA evidence,
61
00:03:21,290 --> 00:03:25,570
murders his surgeon while under
anaesthetic in a different room.
62
00:03:29,170 --> 00:03:34,768
Could the DNA at the murder scene
been a contaminant or planted?
63
00:03:34,770 --> 00:03:37,528
No. The spatter patterns are
too perfect.
64
00:03:37,530 --> 00:03:39,888
It came from someone who
was in the room at the time.
65
00:03:39,890 --> 00:03:41,530
So, how do you explain it?
66
00:03:44,850 --> 00:03:47,928
How do we know Wilfred
was anaesthetised?
67
00:03:47,930 --> 00:03:50,728
I mean, how do we know it was him?
68
00:03:50,730 --> 00:03:52,368
What, he's got an identical twin?
69
00:03:52,370 --> 00:03:53,848
Bit fantastical, Steve.
70
00:03:53,850 --> 00:03:55,688
I don't know.
71
00:03:55,690 --> 00:03:57,290
There's another explanation.
72
00:03:59,370 --> 00:04:01,488
DNA samples got mixed up.
73
00:04:01,490 --> 00:04:03,488
Ah! No way!
74
00:04:03,490 --> 00:04:06,688
Look, I'm just putting it out there.
Mm-mn. We could run the test again.
75
00:04:06,690 --> 00:04:08,690
Those samples were
handled correctly.
76
00:04:10,130 --> 00:04:12,330
Jack, shall we just run them again?
77
00:04:15,610 --> 00:04:17,370
Right, yep. Good.
78
00:04:18,610 --> 00:04:19,650
OK.
79
00:04:20,770 --> 00:04:22,770
Let me know when toxicology
comes back.
80
00:04:31,090 --> 00:04:34,568
So, the samples got mixed up,
did they? It's always possible.
81
00:04:34,570 --> 00:04:35,610
Mm-hm.
82
00:04:36,610 --> 00:04:39,850
You know who took the swab from
Simi Jacobs. Adam.
83
00:04:41,290 --> 00:04:42,610
What are you suggesting?
84
00:04:44,650 --> 00:04:46,130
Just saying.
85
00:04:52,610 --> 00:04:54,888
PHONE RINGS
86
00:04:54,890 --> 00:04:56,688
VOICEMAIL: You have reached
Dr Adam Yuen.
87
00:04:56,690 --> 00:04:58,288
I am unable to take your call.
88
00:04:58,290 --> 00:05:00,250
Please leave a message
after the tone.
89
00:05:03,050 --> 00:05:05,608
Do you know what I don't understand?
90
00:05:05,610 --> 00:05:07,808
It was just a six-month placement,
91
00:05:07,810 --> 00:05:10,448
and his CV is impressive
enough without it.
92
00:05:10,450 --> 00:05:13,610
So, why did he risk his career
and lie about it?
93
00:05:16,570 --> 00:05:18,888
Has he lied about anything else?
94
00:05:18,890 --> 00:05:21,408
Everything else checks out.
95
00:05:21,410 --> 00:05:22,890
Are you sure about that?
96
00:05:26,330 --> 00:05:30,010
You have an injury over your
left eye and a wound on your neck.
97
00:05:31,490 --> 00:05:33,450
How do you account for them, Simi?
98
00:05:34,690 --> 00:05:36,168
Yeah, I got mugged.
99
00:05:36,170 --> 00:05:38,610
A kid with a knife. Really?
100
00:05:40,370 --> 00:05:42,648
And did you report the assault?
101
00:05:42,650 --> 00:05:45,208
No. Why not?
102
00:05:45,210 --> 00:05:46,810
What, are you going to catch him?
103
00:05:48,970 --> 00:05:52,290
He's answered your questions,
so unless you have other evidence?
104
00:06:05,730 --> 00:06:07,570
PHONE PINGS
105
00:06:15,530 --> 00:06:18,928
Tox results from the syringe
used in the attack on Wilfred.
106
00:06:18,930 --> 00:06:20,690
Here we go. Let's have a look.
107
00:06:25,810 --> 00:06:28,010
That's it? Midazolam?
108
00:06:30,250 --> 00:06:32,448
That's a sedative, isn't it?
109
00:06:32,450 --> 00:06:33,490
Yeah.
110
00:06:35,650 --> 00:06:39,728
The full syringe would have had
about five milligrams in it.
111
00:06:39,730 --> 00:06:40,850
That's not very much.
112
00:06:41,890 --> 00:06:45,968
So, either the assailant
is incompetent,
113
00:06:45,970 --> 00:06:48,250
or this wasn't intended to kill him.
114
00:06:49,770 --> 00:06:52,648
So, what's the aim?
115
00:06:52,650 --> 00:06:54,290
Kidnapping?
116
00:06:57,050 --> 00:06:59,128
HE SIGHS
117
00:06:59,130 --> 00:07:01,248
The guy's already ill.
118
00:07:01,250 --> 00:07:03,568
You know...
119
00:07:03,570 --> 00:07:07,528
If someone wanted him dead, it's not
going to be that hard, is it?
120
00:07:07,530 --> 00:07:08,850
He's got leukaemia.
121
00:07:10,690 --> 00:07:13,450
It would look like natural causes
if he died of sepsis.
122
00:07:16,010 --> 00:07:19,010
Should I get that syringe tested
again for bacteria?
123
00:07:25,770 --> 00:07:28,368
What's this about Mr Okoye
being moved?
124
00:07:28,370 --> 00:07:29,808
It's for his own safety.
125
00:07:29,810 --> 00:07:32,488
To the Cowley Institute?
And who's paying for that?
126
00:07:32,490 --> 00:07:35,448
Oh, I've been assured that they have
all the facilities required,
127
00:07:35,450 --> 00:07:38,208
and they've offered to do
the treatment free of charge.
128
00:07:38,210 --> 00:07:39,608
I will not allow it.
129
00:07:39,610 --> 00:07:42,850
Someone in your hospital is trying
to kill Mr Okoye.
130
00:07:44,370 --> 00:07:47,530
Quite frankly, Dr Braithwaite,
I don't need your permission.
131
00:08:00,130 --> 00:08:01,410
Haematology lab.
132
00:08:02,810 --> 00:08:04,808
Dr Braithwaite here.
133
00:08:04,810 --> 00:08:09,608
Wilfred Okoye, hospital number
1187266.
134
00:08:09,610 --> 00:08:12,128
I want all his stored blood
and marrow samples sent
135
00:08:12,130 --> 00:08:13,770
to my office immediately.
136
00:08:40,930 --> 00:08:43,048
Finished!
137
00:08:43,050 --> 00:08:47,810
79 needles swabbed and ready to go.
138
00:08:49,370 --> 00:08:51,728
You've got to see this.
139
00:08:51,730 --> 00:08:53,728
Microbiology results from
the syringe
140
00:08:53,730 --> 00:08:55,968
used in the attack on Wilfred.
141
00:08:55,970 --> 00:08:59,210
Turns out it is full of bacteria -
E coli.
142
00:09:00,970 --> 00:09:03,128
Well, it was lying around on
the floor.
143
00:09:03,130 --> 00:09:04,408
Could it be a contaminant?
144
00:09:04,410 --> 00:09:07,088
No. It's a pure growth -
just one type of bug in there.
145
00:09:07,090 --> 00:09:08,968
If it was a contaminant
you'd expect to see
146
00:09:08,970 --> 00:09:10,728
lots of different organisms.
147
00:09:10,730 --> 00:09:12,370
It's been created deliberately.
148
00:09:13,610 --> 00:09:17,368
So, what? The killer sneaks into
Wilfred's room pretending
149
00:09:17,370 --> 00:09:20,928
to be a nurse, inoculates him with
the bacteria,
150
00:09:20,930 --> 00:09:22,290
but adds a mild sedative...
151
00:09:24,490 --> 00:09:27,328
..so that when the real nurse comes
in with his medication,
152
00:09:27,330 --> 00:09:30,930
he's asleep and can't tell her that
someone else has already been in.
153
00:09:32,130 --> 00:09:33,848
He gets sepsis, he dies.
154
00:09:33,850 --> 00:09:35,330
Looks like natural causes.
155
00:09:36,890 --> 00:09:38,608
I need to tell DI Cracknell.
156
00:09:38,610 --> 00:09:41,210
You need to tell the doctors
looking after Wilfred.
157
00:09:45,370 --> 00:09:49,570
HEART MONITOR BEEPS
158
00:09:50,810 --> 00:09:53,010
HE BREATHES RAPIDLY
159
00:09:55,610 --> 00:09:58,250
ALARM SOUNDS
160
00:10:03,690 --> 00:10:05,570
HEART MONITOR BEEPS RAPIDLY
161
00:10:08,890 --> 00:10:11,010
HEART MONITOR FLATLINES
162
00:10:34,490 --> 00:10:37,408
It's as we expected - extensive
peripheral oedema,
163
00:10:37,410 --> 00:10:40,728
multiple organ failure,
consistent with sepsis.
164
00:10:40,730 --> 00:10:44,728
Yep. Toxicology shows only
medications used for his treatment,
165
00:10:44,730 --> 00:10:48,208
antibiotics, ceftriaxone,
gentamicin present
166
00:10:48,210 --> 00:10:49,928
in therapeutic concentrations.
167
00:10:49,930 --> 00:10:53,288
So, cause of death is consistent
with deliberate inoculation
168
00:10:53,290 --> 00:10:56,168
of the culture of E coli,
on a background
169
00:10:56,170 --> 00:10:59,568
of chemotherapy-induced
immune compromise.
170
00:10:59,570 --> 00:11:02,688
Well, we've got no other
leads on his attacker at present.
171
00:11:02,690 --> 00:11:05,088
We're liaising with
the Beninese Consulate to inform
172
00:11:05,090 --> 00:11:07,688
the family of the deceased.
173
00:11:07,690 --> 00:11:13,048
DNA says Wilfred Okoye was guilty of
Rahul's murder,
174
00:11:13,050 --> 00:11:15,410
but being unconscious,
had the perfect alibi.
175
00:11:17,090 --> 00:11:20,088
When a murder suspect gets murdered,
what does that mean?
176
00:11:20,090 --> 00:11:21,808
Framed by the real murderer?
177
00:11:21,810 --> 00:11:24,410
Why would you frame someone with
the perfect alibi?
178
00:11:30,610 --> 00:11:32,808
Simi Jacobs.
179
00:11:32,810 --> 00:11:34,488
What's his home address?
180
00:11:34,490 --> 00:11:35,530
Erm...
181
00:11:37,370 --> 00:11:41,128
Let's see. Flat 32, Bardwell House,
Lincoln Street.
182
00:11:41,130 --> 00:11:44,768
Thought so. Okoye and Jacobs have
been living together.
183
00:11:44,770 --> 00:11:47,968
Simi Jacobs has already been
released, guv.
184
00:11:47,970 --> 00:11:50,568
What? Yeah. Lack of forensics.
185
00:11:50,570 --> 00:11:52,048
All right.
186
00:11:52,050 --> 00:11:54,050
Might I suggest we pick
him up again?
187
00:12:01,210 --> 00:12:03,288
It still doesn't get us anywhere.
188
00:12:03,290 --> 00:12:05,048
It doesn't explain the DNA.
189
00:12:05,050 --> 00:12:07,448
And Simi was in custody
when Wilfred was attacked,
190
00:12:07,450 --> 00:12:08,848
so it doesn't even explain that.
191
00:12:08,850 --> 00:12:11,330
We're just going round in
circles. Yep.
192
00:12:22,210 --> 00:12:25,368
When he was interviewed,
Wilfred said his leukaemia
193
00:12:25,370 --> 00:12:28,050
was common in his region.
194
00:12:30,690 --> 00:12:32,050
Doesn't sound right to me.
195
00:12:47,010 --> 00:12:48,888
PHONE RINGS
196
00:12:48,890 --> 00:12:50,928
VOICEMAIL: You have reached
Dr Adam Yuen.
197
00:12:50,930 --> 00:12:52,368
I am unable to take your call.
198
00:12:52,370 --> 00:12:54,330
Please leave a message
after the tone.
199
00:12:57,250 --> 00:12:59,208
Wait there. He's not in, guv.
200
00:12:59,210 --> 00:13:00,888
And the neighbours haven't seen him.
201
00:13:00,890 --> 00:13:03,168
He's not been seen back at work
at the hospital either.
202
00:13:03,170 --> 00:13:06,048
You two stick around in case
he comes back.
203
00:13:06,050 --> 00:13:09,290
I'm sorry, guv. I should
have spotted the address.
204
00:13:11,090 --> 00:13:13,048
Don't worry about it.
205
00:13:13,050 --> 00:13:16,210
At least you didn't wrongly arrest
a bereaved cancer patient.
206
00:13:20,570 --> 00:13:22,090
I'll do that next time.
207
00:13:26,410 --> 00:13:27,450
Bye.
208
00:13:32,410 --> 00:13:34,650
Nine missed calls.
You're very persistent.
209
00:13:37,650 --> 00:13:39,290
I didn't want to end it like that.
210
00:13:41,930 --> 00:13:43,610
Can I help?
211
00:13:54,610 --> 00:13:57,648
You should have told me that
Emily Braithwaite is your godmother.
212
00:13:57,650 --> 00:13:59,568
Some godmother.
213
00:13:59,570 --> 00:14:02,168
No doubt you've received
the incriminating evidence about me.
214
00:14:02,170 --> 00:14:03,370
What evidence?
215
00:14:05,010 --> 00:14:07,768
She never sent it.
I should have guessed.
216
00:14:07,770 --> 00:14:10,928
If she tried to blackmail you,
then we'll make her answer for that.
217
00:14:10,930 --> 00:14:12,050
She's far too clever.
218
00:14:14,010 --> 00:14:16,930
Why do I think there's more to this
than you're telling me?
219
00:14:18,650 --> 00:14:20,888
No, I just lied to advance
my career.
220
00:14:20,890 --> 00:14:23,930
Really? Just to say you had a
fellowship. Why would you do that?
221
00:14:29,490 --> 00:14:31,008
My family are all doctors.
222
00:14:31,010 --> 00:14:33,008
I was always going to be a surgeon.
223
00:14:33,010 --> 00:14:34,730
It was more or less decided for me.
224
00:14:36,610 --> 00:14:39,728
Final year of medical school,
I was walking to uni
225
00:14:39,730 --> 00:14:42,968
and a cyclist is knocked off her
bike, right in front of me.
226
00:14:42,970 --> 00:14:44,808
Now, I was a keen student.
227
00:14:44,810 --> 00:14:47,888
I used to carry
a first aid kit around with me.
228
00:14:47,890 --> 00:14:51,568
If I'm honest, I was always waiting
for something like this.
229
00:14:51,570 --> 00:14:54,968
When I think about that it's
actually what I'm most ashamed of.
230
00:14:54,970 --> 00:14:57,248
She had facial injuries.
231
00:14:57,250 --> 00:14:59,888
Heavy, laboured breathing.
She was losing consciousness fast.
232
00:14:59,890 --> 00:15:01,808
So, I thought, "She's suffocating.
233
00:15:01,810 --> 00:15:06,168
"She needs a surgical airway,
a cricothyroidotomy."
234
00:15:06,170 --> 00:15:07,528
So, I made my incision.
235
00:15:07,530 --> 00:15:10,048
Something that I had
practised on mannequins.
236
00:15:10,050 --> 00:15:14,208
What I didn't know is that she had
an abnormal anatomy -
237
00:15:14,210 --> 00:15:17,650
an aberrant subclavian artery,
looping high in the neck.
238
00:15:18,810 --> 00:15:22,128
It's present in 1% of people
and 0% of mannequins.
239
00:15:22,130 --> 00:15:24,530
How could you have known?
It was a bloodbath.
240
00:15:32,210 --> 00:15:35,048
The artery retracted back into
her chest.
241
00:15:35,050 --> 00:15:37,648
There was nothing we could do
to save her.
242
00:15:37,650 --> 00:15:39,810
She bled to death in minutes.
243
00:15:44,250 --> 00:15:46,770
My father was furious.
244
00:15:48,450 --> 00:15:51,128
Not because I stupidly tried
a tracheostomy
245
00:15:51,130 --> 00:15:52,890
and killed an innocent young girl.
246
00:15:54,490 --> 00:15:58,290
But because I didn't study hard
enough to do it competently.
247
00:16:00,530 --> 00:16:05,008
So, he used his influence
and arranged for my fellowship
248
00:16:05,010 --> 00:16:06,770
as cover. For what?
249
00:16:10,690 --> 00:16:12,170
For my absence.
250
00:16:15,490 --> 00:16:18,770
It took months of therapy before
I could even leave the house.
251
00:16:27,530 --> 00:16:31,128
The irony in all of this is that
the one who helped me out
252
00:16:31,130 --> 00:16:32,810
the most was Emily Braithwaite.
253
00:16:34,250 --> 00:16:36,850
She visited me more often than
my parents.
254
00:16:39,890 --> 00:16:41,130
She understood.
255
00:16:44,050 --> 00:16:46,370
But there was no way I was going
to be a surgeon.
256
00:16:50,050 --> 00:16:52,688
So, I decided to choose pathology,
257
00:16:52,690 --> 00:16:56,570
and a false narrative was created as
to why I made the switch.
258
00:16:58,250 --> 00:17:01,168
When you start lying,
259
00:17:01,170 --> 00:17:03,450
you have to keep lying.
260
00:17:23,250 --> 00:17:25,288
Jack. Mm? I need to talk to you.
261
00:17:25,290 --> 00:17:26,650
Sure, what's up...?
262
00:17:29,170 --> 00:17:30,568
Hi.
263
00:17:30,570 --> 00:17:31,690
Are you kidding me?
264
00:17:35,050 --> 00:17:37,408
He doesn't work here any more
because he lied to us, do you
265
00:17:37,410 --> 00:17:40,128
remember? Do you remember that?
Adam's got a theory about Wilfred.
266
00:17:40,130 --> 00:17:41,688
Oh, right. Just hear him out.
267
00:17:41,690 --> 00:17:45,688
So, um, I just have to trust
him now?
268
00:17:45,690 --> 00:17:47,690
No, you've got to trust me.
269
00:17:51,570 --> 00:17:52,690
Think about it.
270
00:17:54,010 --> 00:17:56,648
Why would someone want Wilfred dead?
271
00:17:56,650 --> 00:17:58,928
What did he know that was such
a threat that someone
272
00:17:58,930 --> 00:17:59,970
had to kill him?
273
00:18:01,610 --> 00:18:05,048
Wilfred was being treated for acute
myeloid leukaemia.
274
00:18:05,050 --> 00:18:06,288
That's rare.
275
00:18:06,290 --> 00:18:08,808
Remember, he said there were
lots of other cases in his small
276
00:18:08,810 --> 00:18:11,008
village in Africa.
277
00:18:11,010 --> 00:18:13,728
What if Wilfred wasn't killed
because of what he knew?
278
00:18:13,730 --> 00:18:14,888
Don't follow.
279
00:18:14,890 --> 00:18:16,690
Wilfred wasn't the witness.
280
00:18:18,850 --> 00:18:20,170
He was the evidence.
281
00:18:23,650 --> 00:18:26,048
This is a trephine biopsy of
the bone marrow.
282
00:18:26,050 --> 00:18:29,768
We take a thin core of bone
with marrow cells in it.
283
00:18:29,770 --> 00:18:32,090
I've already taken an aspirate of
the fluids.
284
00:18:43,330 --> 00:18:46,808
So, the question is, why would so
many people from one place
285
00:18:46,810 --> 00:18:48,210
all get leukaemia?
286
00:18:49,450 --> 00:18:51,288
And that's going to tell you, is it?
287
00:18:51,290 --> 00:18:53,128
To be honest, I've never done
this before.
288
00:18:53,130 --> 00:18:55,128
Not postmortem, anyway.
289
00:18:55,130 --> 00:18:58,290
But you know what? It's crazy
enough for it to work. Mm-mm.
290
00:19:10,050 --> 00:19:11,090
Thanks.
291
00:19:13,130 --> 00:19:16,490
Oh, look. Here's a billion
DNA results from the needles.
292
00:19:18,090 --> 00:19:21,048
Want to give me a hand going
through these?
293
00:19:21,050 --> 00:19:22,210
Didn't think so.
294
00:19:40,210 --> 00:19:42,890
Nikki? The slide's ready when you
want to have a look.
295
00:19:51,290 --> 00:19:53,928
Good yield of cells.
More than I expected.
296
00:19:53,930 --> 00:19:56,368
Definitely acute myeloid leukaemia.
297
00:19:56,370 --> 00:19:59,848
It's not typical.
Looks more like secondary AML.
298
00:19:59,850 --> 00:20:02,568
Secondary to what?
A toxin of some sort.
299
00:20:02,570 --> 00:20:04,608
Some industrial chemical,
for example,
300
00:20:04,610 --> 00:20:08,608
or chemotherapy for
a different cancer.
301
00:20:08,610 --> 00:20:11,488
Right. And that can occur years
after the original exposure.
302
00:20:11,490 --> 00:20:13,488
Decades, in some cases.
303
00:20:13,490 --> 00:20:17,050
So, there may be other victims,
all exposed to the same thing?
304
00:20:19,090 --> 00:20:20,450
Makes sense.
305
00:20:22,130 --> 00:20:26,170
BUZZING
306
00:20:39,330 --> 00:20:40,488
Can I help you?
307
00:20:40,490 --> 00:20:42,528
They told me Wilfred is here.
308
00:20:42,530 --> 00:20:44,368
Can I see him, yeah?
309
00:20:44,370 --> 00:20:46,570
Er, you are? Family.
310
00:20:48,850 --> 00:20:50,408
Do you want to take a seat?
311
00:20:50,410 --> 00:20:53,610
Will I be able to sit with him
for a bit or...? I'll just check.
312
00:21:03,090 --> 00:21:05,408
I've found Rahul's murder weapon.
313
00:21:05,410 --> 00:21:09,168
One DNA profile matching Rahul,
one matching Wilfred,
314
00:21:09,170 --> 00:21:10,928
just like we found at the scene.
315
00:21:10,930 --> 00:21:12,930
But there's a third profile.
316
00:21:14,690 --> 00:21:16,808
Yep. Simi Jacobs.
317
00:21:16,810 --> 00:21:18,848
Simi? He's here!
318
00:21:18,850 --> 00:21:21,770
What do you mean he's here?
He wants to see Wilfred's body.
319
00:21:36,850 --> 00:21:39,648
This places Simi at the scene
of Rahul's murder.
320
00:21:39,650 --> 00:21:41,648
We need to keep him here.
321
00:21:41,650 --> 00:21:43,250
Call DI Cracknell.
322
00:21:47,130 --> 00:21:49,648
So, hang on. Simi Jacobs just
turned up at the lab.
323
00:21:49,650 --> 00:21:51,808
One needle injected into
three people.
324
00:21:51,810 --> 00:21:53,248
Better get down here.
325
00:21:53,250 --> 00:21:55,248
Simi had a puncture wound
to his neck.
326
00:21:55,250 --> 00:21:58,208
Rahul was stabbed in the chest,
but Wilfred?
327
00:21:58,210 --> 00:22:00,008
And if Simi got in a fight
with Rahul,
328
00:22:00,010 --> 00:22:01,968
why is Wilfred's blood spattered?
329
00:22:01,970 --> 00:22:04,648
Wilfred would have to have
been in the room as well.
330
00:22:04,650 --> 00:22:06,650
Maybe he was. Genetically speaking.
331
00:22:07,970 --> 00:22:10,488
What if that needle only stabbed
two people?
332
00:22:10,490 --> 00:22:13,368
Then one of them has two different
types of DNA. Exactly.
333
00:22:13,370 --> 00:22:14,928
Huh? No, for that to work, it would
334
00:22:14,930 --> 00:22:17,648
mean Simi's walking around with
Wilfred's blood inside him.
335
00:22:17,650 --> 00:22:19,530
That's ridiculous. Is it?
336
00:22:21,650 --> 00:22:24,808
Bone marrow transplant.
And Wilfred was the donor.
337
00:22:24,810 --> 00:22:28,610
So, Simi's blood has Wilfred's DNA.
338
00:22:36,130 --> 00:22:37,850
Do you want to come this way? Yeah.
339
00:22:42,290 --> 00:22:43,370
Just there.
340
00:22:46,450 --> 00:22:49,208
Can I get you a tea?
A glass of water or...?
341
00:22:49,210 --> 00:22:51,088
Oh, no, no!
342
00:22:51,090 --> 00:22:52,130
Thanks.
343
00:22:55,090 --> 00:22:57,488
You said that Wilfred was family?
344
00:22:57,490 --> 00:22:59,248
That's right.
345
00:22:59,250 --> 00:23:00,890
Was he a close relative?
346
00:23:02,530 --> 00:23:04,848
You ask a lot of questions.
347
00:23:04,850 --> 00:23:06,530
Remember me?
348
00:23:08,330 --> 00:23:10,448
I examined you at the station.
349
00:23:10,450 --> 00:23:11,768
I saw a scar on your chest.
350
00:23:11,770 --> 00:23:13,410
That's a Hickman line scar.
351
00:23:15,010 --> 00:23:17,330
Did you have a bone marrow
transplant as a kid?
352
00:23:18,770 --> 00:23:20,568
Yeah, I'm going to go.
353
00:23:20,570 --> 00:23:23,410
Simi, we found your blood at
the scene of Rahul's murder.
354
00:23:25,410 --> 00:23:26,650
Did you kill him?
355
00:23:29,490 --> 00:23:34,168
No, no, no. He... He came at me!
He was insane!
356
00:23:34,170 --> 00:23:35,490
It was an accident!
357
00:23:39,570 --> 00:23:41,290
I just wanted to protect Wilfred.
358
00:23:43,450 --> 00:23:46,248
Wilfred saved my life
when I was a kid.
359
00:23:46,250 --> 00:23:49,288
But you know what? He could only do
that because he was a match.
360
00:23:49,290 --> 00:23:52,168
People have transplants from their
brothers or mothers or whatever
361
00:23:52,170 --> 00:23:55,090
because they're a match.
I had no-one.
362
00:23:56,490 --> 00:23:59,568
How did you find him? There's this
charity attached to our church.
363
00:23:59,570 --> 00:24:01,570
They helped us get
the transplant records.
364
00:24:03,570 --> 00:24:05,290
Only it turns out Wilfred was sick.
365
00:24:06,490 --> 00:24:08,688
Were there others? Yeah.
366
00:24:08,690 --> 00:24:11,730
I mean, loads of people in his
village died from the same thing.
367
00:24:13,730 --> 00:24:15,370
We found Wilfred in time.
368
00:24:17,930 --> 00:24:19,370
So we thought.
369
00:24:21,290 --> 00:24:23,448
What?
370
00:24:23,450 --> 00:24:25,170
You're not going to let me see him?
371
00:24:29,250 --> 00:24:31,968
Simi.
372
00:24:31,970 --> 00:24:33,210
There he is.
373
00:24:53,730 --> 00:24:57,168
Ah, afternoon! Present from
DI Cracknell -
374
00:24:57,170 --> 00:25:00,008
all the rubbish from
Simi Jacobs' address.
375
00:25:00,010 --> 00:25:01,488
Thought you might want to take
a look
376
00:25:01,490 --> 00:25:03,288
in case you find anything relevant.
377
00:25:03,290 --> 00:25:07,648
Joy. Can I introduce Reverend Kanu?
You've already met Jack.
378
00:25:07,650 --> 00:25:11,688
This is Dr Nikki Alexander
and Dr Adam Yuen. Hello.
379
00:25:11,690 --> 00:25:15,088
Reverend Kanu runs the charitable
organisation that was responsible
380
00:25:15,090 --> 00:25:16,968
for bringing Wilfred to the UK.
381
00:25:16,970 --> 00:25:18,768
I have some photos from our trip.
382
00:25:18,770 --> 00:25:22,488
Sergeant Galloway thinks
they might help you. Thank you.
383
00:25:22,490 --> 00:25:24,930
I have to warn you,
they're not pretty.
384
00:25:28,090 --> 00:25:30,330
Tell me how Mr Okoye came to
be here.
385
00:25:31,930 --> 00:25:36,128
My church runs a charity that helps
arrange treatment in the UK.
386
00:25:36,130 --> 00:25:38,930
They raise money, get doctors to
volunteer, whatever.
387
00:25:40,410 --> 00:25:42,768
Wilfred's case was kind of special.
388
00:25:42,770 --> 00:25:46,448
I mean, he helped me years ago,
and now he needed my help.
389
00:25:46,450 --> 00:25:48,768
The local newspaper picked up
the story, it got a lot
390
00:25:48,770 --> 00:25:52,168
of publicity. So, the hospital
agreed to treat him.
391
00:25:52,170 --> 00:25:54,650
And he stayed at your flat? Yeah.
392
00:25:56,890 --> 00:25:59,768
Nobody told me he don't
speak English.
393
00:25:59,770 --> 00:26:02,608
I couldn't tell him anything.
394
00:26:02,610 --> 00:26:05,850
He didn't know who I was,
what he did for me.
395
00:26:08,210 --> 00:26:11,010
Then I learnt that he's under
the care of this Rahul guy.
396
00:26:12,850 --> 00:26:17,648
I have travelled widely in Africa
as part of my ministry,
397
00:26:17,650 --> 00:26:22,530
and yet nothing could have prepared
me for what we found in Bwendora.
398
00:26:25,410 --> 00:26:28,690
The town is remote, even by
African standards.
399
00:26:30,170 --> 00:26:33,408
There is only very basic
health care.
400
00:26:33,410 --> 00:26:36,210
It became clear there was a
lot of sickness.
401
00:26:38,010 --> 00:26:40,810
This man died within hours of
our arrival.
402
00:26:41,970 --> 00:26:46,408
The illness causes bleeding
and rashes. Fever sometimes.
403
00:26:46,410 --> 00:26:48,568
What do the people think it's
caused by?
404
00:26:48,570 --> 00:26:51,688
There's a large pesticide factory
in the town.
405
00:26:51,690 --> 00:26:54,848
Many people think the water has
been contaminated.
406
00:26:54,850 --> 00:26:57,808
They organised protests.
407
00:26:57,810 --> 00:27:00,768
People think there has been
a cover-up.
408
00:27:00,770 --> 00:27:03,170
But the factory provides
a lot of employment.
409
00:27:04,530 --> 00:27:08,248
It is a very divisive issue.
410
00:27:08,250 --> 00:27:12,968
The illness has ripped the heart
out of the community.
411
00:27:12,970 --> 00:27:16,008
There are very few families it has
left untouched.
412
00:27:16,010 --> 00:27:17,968
And they've had no outside help?
413
00:27:17,970 --> 00:27:21,208
There is one western charity
which runs a clinic,
414
00:27:21,210 --> 00:27:23,090
but they only visit every
few months.
415
00:27:25,730 --> 00:27:26,930
Some charity.
416
00:27:29,730 --> 00:27:31,888
Oh, Lord.
417
00:27:31,890 --> 00:27:33,810
Enlighten our minds with your truth.
418
00:27:36,130 --> 00:27:39,290
Give us the strength and the wisdom
to seek justice.
419
00:27:40,970 --> 00:27:44,770
Shine your everlasting light into
our darkness.
420
00:27:47,130 --> 00:27:50,528
There's a lot of talk about Rahul,
all around the hospital.
421
00:27:50,530 --> 00:27:52,968
How the hospital is protecting him.
422
00:27:52,970 --> 00:27:56,408
How he messed up an operation
and no-one wants to work with him.
423
00:27:56,410 --> 00:27:59,128
And you thought he shouldn't operate
on Wilfred.
424
00:27:59,130 --> 00:28:03,128
The night before, I heard him
arguing with this woman,
425
00:28:03,130 --> 00:28:05,248
Dr Braithwaite.
426
00:28:05,250 --> 00:28:07,328
She told Rahul not to do
the operation
427
00:28:07,330 --> 00:28:10,128
and he just told her that
she couldn't stop him.
428
00:28:10,130 --> 00:28:12,648
The bag of rubbish that we
found at your home address.
429
00:28:12,650 --> 00:28:14,648
Was it from one of the offices?
430
00:28:14,650 --> 00:28:16,090
Yeah. Which one?
431
00:28:17,170 --> 00:28:18,568
All of them.
432
00:28:18,570 --> 00:28:21,008
I was looking for
something, anything,
433
00:28:21,010 --> 00:28:22,848
I could use against Rahul.
434
00:28:22,850 --> 00:28:25,328
And on the morning of the operation?
435
00:28:25,330 --> 00:28:28,288
I saw Wilfred getting prepared for
theatre and I panicked.
436
00:28:28,290 --> 00:28:30,048
I phoned Rahul.
437
00:28:30,050 --> 00:28:31,528
What did you say?
438
00:28:31,530 --> 00:28:33,888
I told him I had some information
on him.
439
00:28:33,890 --> 00:28:38,008
I thought I could threaten to reveal
what I knew if he did the operation.
440
00:28:38,010 --> 00:28:39,210
What information?
441
00:28:41,730 --> 00:28:44,810
I was bluffing. But I had
to stop him.
442
00:28:48,010 --> 00:28:49,770
Well, you certainly managed that.
443
00:29:04,970 --> 00:29:06,448
How's it going?
444
00:29:06,450 --> 00:29:09,850
Oh, I'm in my element rummaging
through the trash. You know me.
445
00:29:10,930 --> 00:29:13,288
Nothing much here, apart from
a criminally lax attitude
446
00:29:13,290 --> 00:29:14,330
to recycling.
447
00:29:16,530 --> 00:29:18,528
Adam's still here, is he?
448
00:29:18,530 --> 00:29:20,528
We wouldn't have got this far
without him.
449
00:29:20,530 --> 00:29:22,170
I want to trust him.
450
00:29:24,570 --> 00:29:25,690
What's that?
451
00:29:30,610 --> 00:29:31,650
Oh, my God.
452
00:29:33,130 --> 00:29:37,728
This was in that rubbish bag you
found at Simi Jacobs' place.
453
00:29:37,730 --> 00:29:40,848
It's Harry Fletcher's ECG,
taken the day of his operation.
454
00:29:40,850 --> 00:29:42,128
It's normal.
455
00:29:42,130 --> 00:29:45,968
And this is the ECG that
appeared in Fletcher's notes.
456
00:29:45,970 --> 00:29:49,048
Same date and time,
but grossly abnormal.
457
00:29:49,050 --> 00:29:52,848
We believe they were switched
to deflect blame from Rahul
458
00:29:52,850 --> 00:29:55,208
after the operation went wrong.
459
00:29:55,210 --> 00:29:57,168
So, there was a cover-up?
460
00:29:57,170 --> 00:29:59,888
Well, what's this got to do with
the murder investigation?
461
00:29:59,890 --> 00:30:02,848
Yeah, Simi Jacobs admitted to
the attack on Arnie Rahul.
462
00:30:02,850 --> 00:30:05,728
I mean, he claims it was an accident
as a result of self-defence.
463
00:30:05,730 --> 00:30:07,448
That fits with the
crime scene findings.
464
00:30:07,450 --> 00:30:09,808
So, how does this transplant fit in?
465
00:30:09,810 --> 00:30:12,568
Well, Simi was born with
sickle cell disease,
466
00:30:12,570 --> 00:30:16,728
and was treated with a bone marrow
transplant at St Jude's as a child.
467
00:30:16,730 --> 00:30:19,528
Wilfred donated his stem cells
for Simi's transplant.
468
00:30:19,530 --> 00:30:21,888
20 years later,
Wilfred gets leukaemia.
469
00:30:21,890 --> 00:30:23,768
We don't think
this is a coincidence.
470
00:30:23,770 --> 00:30:27,008
He had a type of leukaemia
that can be caused by over-exposure
471
00:30:27,010 --> 00:30:28,288
to certain drugs.
472
00:30:28,290 --> 00:30:31,688
There's a technique known as
mobilisation,
473
00:30:31,690 --> 00:30:34,568
which is designed to increase
production of stem cells.
474
00:30:34,570 --> 00:30:38,768
Normally, stem cell donation
involves giving a perfectly safe
475
00:30:38,770 --> 00:30:40,288
bone marrow stimulant.
476
00:30:40,290 --> 00:30:45,208
But whoever did this also gave
Wilfred high levels of chemotherapy,
477
00:30:45,210 --> 00:30:47,048
and did so repeatedly.
478
00:30:47,050 --> 00:30:49,408
They gave chemo? To a volunteer?
479
00:30:49,410 --> 00:30:51,568
To yield even more stem cells.
480
00:30:51,570 --> 00:30:53,808
What for? More transplants?
481
00:30:53,810 --> 00:30:58,728
Stem cells have the ability to
develop into any type of body cell.
482
00:30:58,730 --> 00:31:00,688
Brain, heart, blood -
you name it.
483
00:31:00,690 --> 00:31:03,008
So there's a huge range
of potential therapies
484
00:31:03,010 --> 00:31:06,568
in which they can be used,
one of which is transplantation.
485
00:31:06,570 --> 00:31:11,248
About ten years ago, Braithwaite
and her team identified stem cells
486
00:31:11,250 --> 00:31:13,448
that were very special indeed,
487
00:31:13,450 --> 00:31:17,008
capable of being turned into
what are called killer T-cells,
488
00:31:17,010 --> 00:31:21,088
part of the immune system, which can
be made to attack malignant tumours.
489
00:31:21,090 --> 00:31:23,448
The potential for this discovery
was enormous.
490
00:31:23,450 --> 00:31:25,768
These magic cells
all had the same gene,
491
00:31:25,770 --> 00:31:30,088
a gene we think might be common
in Wilfred's town.
492
00:31:30,090 --> 00:31:33,888
They went looking for transplant
donors to treat people like Simi,
493
00:31:33,890 --> 00:31:36,688
but what they discovered
was something much bigger,
494
00:31:36,690 --> 00:31:38,808
so they went back for more,
and more.
495
00:31:38,810 --> 00:31:41,448
Basically they were flogging him
for every last stem cell
496
00:31:41,450 --> 00:31:43,848
he could produce.
Him and all the others.
497
00:31:43,850 --> 00:31:46,168
Wilfred's town was basically
a stem cell farm.
498
00:31:46,170 --> 00:31:49,608
Can you prove Wilfred
was given the stimulating drugs?
499
00:31:49,610 --> 00:31:52,810
It may be possible,
but that's way out of my league.
500
00:31:54,530 --> 00:31:56,410
Sounds like we need
a second opinion.
501
00:32:16,410 --> 00:32:17,728
Thank you, Professor.
502
00:32:17,730 --> 00:32:19,368
Not at all.
It's very good to see you.
503
00:32:19,370 --> 00:32:20,890
Thank you.
Oh, he's away!
504
00:32:22,730 --> 00:32:26,168
Adam, hello again.
Hello. This is Dr Nikki Alexander.
505
00:32:26,170 --> 00:32:28,528
Hello. How do you do?
And you've already met DI Cracknell.
506
00:32:28,530 --> 00:32:30,130
Yes, of course. This way.
507
00:32:31,090 --> 00:32:32,768
That was Alfie.
508
00:32:32,770 --> 00:32:36,888
He's one of our early trial patients
- osteosarcoma.
509
00:32:36,890 --> 00:32:39,008
When he was referred to us,
he was in a hospice
510
00:32:39,010 --> 00:32:42,568
on palliative treatment,
expected to die within weeks.
511
00:32:42,570 --> 00:32:44,970
Please. That was two years ago.
512
00:32:46,370 --> 00:32:47,730
He's now disease-free.
513
00:32:50,490 --> 00:32:53,968
We wanted to show you some
bone marrow samples from Mr Okoye.
514
00:32:53,970 --> 00:32:56,210
He was moved from St Jude's
to be treated here.
515
00:33:04,690 --> 00:33:06,648
Hmm.
516
00:33:06,650 --> 00:33:08,290
Secondary leukaemia.
517
00:33:11,170 --> 00:33:12,648
They look very unusual.
518
00:33:12,650 --> 00:33:15,488
Mr Okoye was a stem cell donor.
519
00:33:15,490 --> 00:33:17,208
Was he?
520
00:33:17,210 --> 00:33:20,448
We were wondering
if it might be stimulated.
521
00:33:20,450 --> 00:33:21,810
You mean Cyclo-G?
522
00:33:23,130 --> 00:33:24,608
Oh, dear.
523
00:33:24,610 --> 00:33:28,168
Yes, it's possible.
524
00:33:28,170 --> 00:33:31,088
Is there any way we can confirm it?
525
00:33:31,090 --> 00:33:33,968
You would need to look into
the genetics of his blood cells.
526
00:33:33,970 --> 00:33:36,088
There are some telltale signs.
527
00:33:36,090 --> 00:33:39,448
We have several world experts
in cytogenetics here.
528
00:33:39,450 --> 00:33:41,688
They'd be happy to help.
529
00:33:41,690 --> 00:33:44,688
Your cancer therapies are based
on Braithwaite's stem cell research,
530
00:33:44,690 --> 00:33:48,808
are they not?
Yes. Yes. I've never denied it.
531
00:33:48,810 --> 00:33:51,490
Hers was an extraordinary
piece of work.
532
00:33:52,650 --> 00:33:55,728
She tried for years to turn it into
a practical treatment,
533
00:33:55,730 --> 00:34:00,328
but, in the end, she was stumped
by the obvious problem.
534
00:34:00,330 --> 00:34:02,208
The limited supply of donors.
535
00:34:02,210 --> 00:34:03,488
Precisely.
536
00:34:03,490 --> 00:34:07,890
So, what we brought to the party
is called gene editing.
537
00:34:09,130 --> 00:34:12,768
We found a way of inserting
the special gene
538
00:34:12,770 --> 00:34:15,170
into any old stem cell,
and the result is...
539
00:34:16,250 --> 00:34:17,730
Well, you met Alfie.
540
00:34:18,810 --> 00:34:21,290
What is your relationship
to Emily Braithwaite?
541
00:34:22,890 --> 00:34:24,408
Yes.
542
00:34:24,410 --> 00:34:27,568
Well, I suppose you'd say
we're rivals.
543
00:34:27,570 --> 00:34:31,448
She's never forgiven me
for succeeding where she failed.
544
00:34:31,450 --> 00:34:35,448
But I'm afraid her star
has been waning for some time.
545
00:34:35,450 --> 00:34:36,890
What makes you say that?
546
00:34:39,170 --> 00:34:41,168
She came to ask for my help.
547
00:34:41,170 --> 00:34:44,888
Believe me,
that alone suggests desperation.
548
00:34:44,890 --> 00:34:48,608
She had just lost a very large
research grant.
549
00:34:48,610 --> 00:34:51,168
Is it possible that Braithwaite
poisoned Mr Okoye
550
00:34:51,170 --> 00:34:54,528
and everyone else in his town
to get more stem cells?
551
00:34:54,530 --> 00:34:57,248
That's a serious accusation.
552
00:34:57,250 --> 00:34:59,088
Everything's falling apart.
553
00:34:59,090 --> 00:35:01,488
So, like a gambler,
she risks more and more,
554
00:35:01,490 --> 00:35:04,170
desperate for that big win
to get herself back on top.
555
00:35:14,050 --> 00:35:19,650
THEY CONFER
556
00:35:22,810 --> 00:35:24,450
PHONE PINGS
557
00:35:59,650 --> 00:36:01,250
Now what?
Excuse me?
558
00:36:02,410 --> 00:36:05,648
You do realise my career is over?
And that's my fault?
559
00:36:05,650 --> 00:36:07,528
There's got to be a way out of this.
560
00:36:07,530 --> 00:36:08,850
You owe me that at least.
561
00:36:10,130 --> 00:36:12,770
You want Auntie Emily
to make it better?
562
00:36:14,290 --> 00:36:18,488
All those years I stuck up for you
with your father.
563
00:36:18,490 --> 00:36:21,408
You messed up. Again.
564
00:36:21,410 --> 00:36:23,170
For once in your life, own it.
565
00:36:25,450 --> 00:36:27,048
I don't get it.
566
00:36:27,050 --> 00:36:28,568
You and Rahul.
567
00:36:28,570 --> 00:36:30,768
You go to all these lengths
to protect his reputation,
568
00:36:30,770 --> 00:36:33,528
yet you show no interest
in who might have killed him.
569
00:36:33,530 --> 00:36:35,890
You don't even seem to even care
that he's dead!
570
00:36:37,290 --> 00:36:39,850
Maybe I've learnt to
bury my emotions.
571
00:36:41,690 --> 00:36:42,890
You should try it.
572
00:36:44,810 --> 00:36:46,888
You know they're onto you,
573
00:36:46,890 --> 00:36:49,608
and I'm not going to help you
this time.
574
00:36:49,610 --> 00:36:50,890
Oh, please.
575
00:36:52,490 --> 00:36:53,930
This is so painful.
576
00:37:00,690 --> 00:37:03,128
So, all roads lead to Braithwaite.
577
00:37:03,130 --> 00:37:05,448
Yes, but it's all circumstantial.
578
00:37:05,450 --> 00:37:08,128
There's nothing directly
connecting her to Wilfred.
579
00:37:08,130 --> 00:37:10,488
If you can find me something
concrete, I'll bring her in,
580
00:37:10,490 --> 00:37:12,408
but until then,
it's just speculation.
581
00:37:12,410 --> 00:37:14,808
Adam, where did you get to?
582
00:37:14,810 --> 00:37:17,368
Rahul's conduct during
Fletcher's operation amounted to
583
00:37:17,370 --> 00:37:19,328
criminal negligence.
584
00:37:19,330 --> 00:37:21,408
He could have been charged
for manslaughter.
585
00:37:21,410 --> 00:37:22,768
Well, he's dead.
586
00:37:22,770 --> 00:37:24,728
What if Braithwaite covered it up?
587
00:37:24,730 --> 00:37:27,128
That's attempting to pervert
the course of justice.
588
00:37:27,130 --> 00:37:28,648
Which means you can arrest her.
589
00:37:28,650 --> 00:37:31,728
Oh, and how do we know that
Braithwaite swaps the ECG?
590
00:37:31,730 --> 00:37:34,128
We can't. There are several
sets of prints on the trace,
591
00:37:34,130 --> 00:37:35,728
one of which could be Braithwaite's.
592
00:37:35,730 --> 00:37:38,168
Exactly, so we can't just arrest her
on the off-chance that
593
00:37:38,170 --> 00:37:39,608
her prints are on there.
I know.
594
00:37:39,610 --> 00:37:41,090
ADAM: I met her for a drink.
595
00:37:45,050 --> 00:37:46,808
Her prints are on this glass.
596
00:37:46,810 --> 00:37:50,048
When you find that they are
the same as the sets on the ECG,
597
00:37:50,050 --> 00:37:52,808
then you can arrest her.
That's not admissible as evidence!
598
00:37:52,810 --> 00:37:54,450
It doesn't have to be.
599
00:37:55,970 --> 00:37:59,368
How do we know for sure
she touched this glass?
600
00:37:59,370 --> 00:38:01,570
Well, you're just going to
have to trust me.
601
00:38:48,210 --> 00:38:49,690
You two go round the back.
602
00:38:53,650 --> 00:38:55,130
DOORBELL RINGS
603
00:39:01,330 --> 00:39:03,410
Her car's here.
Looks like she's home.
604
00:39:06,490 --> 00:39:07,530
No letterbox.
605
00:39:12,010 --> 00:39:13,370
Dr Braithwaite?
606
00:39:14,370 --> 00:39:16,730
DS Galloway.
Could you open the door, please?
607
00:39:21,090 --> 00:39:23,210
Police!
Dr Braithwaite?
608
00:39:35,330 --> 00:39:36,410
Shit.
609
00:39:42,690 --> 00:39:44,330
No sign of external injury.
610
00:39:46,170 --> 00:39:49,568
Both front and back doors
were locked from the inside.
611
00:39:49,570 --> 00:39:52,168
There's no signs
of forced entry.
612
00:39:52,170 --> 00:39:53,690
Everything's neat and tidy.
613
00:39:55,850 --> 00:39:57,210
Sudden chest pain, maybe?
614
00:39:58,730 --> 00:39:59,770
Or suicide.
615
00:40:32,210 --> 00:40:35,090
Nikki. Adam. Look at these.
616
00:40:40,610 --> 00:40:43,810
Two samples
with Wilfred Okoye's name on.
617
00:41:06,810 --> 00:41:08,768
Look at this.
618
00:41:08,770 --> 00:41:11,048
The boiler's locked out.
619
00:41:11,050 --> 00:41:12,968
Yeah. Mine does that all the time.
620
00:41:12,970 --> 00:41:14,210
Bloody things.
621
00:41:52,610 --> 00:41:55,170
Heart weighs 380g.
622
00:42:21,330 --> 00:42:24,170
Evidence of left ventricular
hypertrophy.
623
00:42:25,530 --> 00:42:27,010
Valves unremarkable.
624
00:42:30,330 --> 00:42:34,168
Left anterior descending
coronary artery.
625
00:42:34,170 --> 00:42:37,210
Moderate stenosis,
no evidence of thrombus.
626
00:42:45,610 --> 00:42:48,248
The toxicology
was entirely negative,
627
00:42:48,250 --> 00:42:50,808
apart from a modest level
of alcohol.
628
00:42:50,810 --> 00:42:54,768
No paracetamol,
no benzodiazepines, nothing.
629
00:42:54,770 --> 00:42:58,368
So this, together with the absence
of pills and containers
630
00:42:58,370 --> 00:43:01,328
at the address, and the absence
of any needle marks on the body,
631
00:43:01,330 --> 00:43:04,488
leads me to conclude that death
was not as a result
632
00:43:04,490 --> 00:43:07,048
of suicide or poisoning.
633
00:43:07,050 --> 00:43:10,528
In fact, the only significant
finding from the postmortem
634
00:43:10,530 --> 00:43:13,488
examination is moderate ischaemic
heart disease,
635
00:43:13,490 --> 00:43:16,928
together with hypertrophy of the
septum and left ventricular wall.
636
00:43:16,930 --> 00:43:19,888
But no evidence of
coronary thrombosis?
637
00:43:19,890 --> 00:43:22,848
The ventricular wall thickness...
Heart attack. ..and the degree
638
00:43:22,850 --> 00:43:26,648
of myocardial disarray on microscopy
are borderline
639
00:43:26,650 --> 00:43:28,688
for a diagnosis of HCM.
640
00:43:28,690 --> 00:43:31,608
What's that?
Hypertrophic cardiomyopathy.
641
00:43:31,610 --> 00:43:34,968
It's an inherited heart condition
that can lead to sudden death.
642
00:43:34,970 --> 00:43:36,850
Fabrice Muamba.
Yes.
643
00:43:38,770 --> 00:43:42,488
Bolton Wanderers versus Tottenham.
FA Cup quarterfinal, 2012.
644
00:43:42,490 --> 00:43:44,448
He collapsed on the pitch.
Nearly died.
645
00:43:44,450 --> 00:43:46,328
Well, technically he did.
646
00:43:46,330 --> 00:43:48,368
In cases of high stress or exercise,
647
00:43:48,370 --> 00:43:52,488
the heart can lead into an abnormal
rhythm, which can be fatal.
648
00:43:52,490 --> 00:43:55,408
And Emily Braithwaite
was under a lot of stress.
649
00:43:55,410 --> 00:43:59,888
So it is possible that this caused
a dysrhythmic event...
650
00:43:59,890 --> 00:44:02,690
Heart attack. ..that led to
her death, don't you think?
651
00:44:06,690 --> 00:44:08,688
How come she didn't have
a letterbox?
652
00:44:08,690 --> 00:44:11,048
It's a passive house.
It's so well-insulated,
653
00:44:11,050 --> 00:44:13,728
it doesn't need heating.
You heat it up just by living in it.
654
00:44:13,730 --> 00:44:15,488
But it has to be really airtight.
655
00:44:15,490 --> 00:44:17,608
It's like living in a bubble.
656
00:44:17,610 --> 00:44:20,810
All the air goes in and out through
a single ventilation system.
657
00:44:22,450 --> 00:44:25,368
But why would the boiler lock out?
658
00:44:25,370 --> 00:44:29,808
What if it was faulty and produced
a lot of carbon monoxide?
659
00:44:29,810 --> 00:44:32,170
No carbon monoxide in
the toxicology.
660
00:44:36,450 --> 00:44:39,048
She's a suspect in a murder case.
She conveniently dies.
661
00:44:39,050 --> 00:44:40,888
What if others were involved?
662
00:44:40,890 --> 00:44:43,008
If you can tell me how they did it,
I'll believe you,
663
00:44:43,010 --> 00:44:46,528
but until then,
it's looking like natural causes.
664
00:44:46,530 --> 00:44:50,088
Right, then, provisional assumption
is that Braithwaite
665
00:44:50,090 --> 00:44:52,808
was guilty of conspiracy
to murder Wilfred Okoye,
666
00:44:52,810 --> 00:44:55,768
as well as perverting the course
of justice in the Fletcher case.
667
00:44:55,770 --> 00:44:56,968
What about Simi?
668
00:44:56,970 --> 00:45:01,008
That's up to the CPS, whether
they buy a self-defence plea.
669
00:45:01,010 --> 00:45:02,530
I'll keep you posted.
670
00:45:20,530 --> 00:45:22,810
So this is where you've been hiding.
671
00:45:25,010 --> 00:45:26,808
Adam told you, then?
672
00:45:26,810 --> 00:45:29,330
Oh, yeah. He told me everything.
673
00:46:25,730 --> 00:46:27,128
I don't get it.
674
00:46:27,130 --> 00:46:30,128
How could someone like Braithwaite
justify it to herself,
675
00:46:30,130 --> 00:46:31,448
let alone anyone else?
676
00:46:31,450 --> 00:46:33,968
They get fixated on the prize,
don't they?
677
00:46:33,970 --> 00:46:37,530
The breakthrough, and all
the acclaim that goes with it. Mm.
678
00:46:38,650 --> 00:46:41,850
Did you ever want to do something
like that? Fancy research job?
679
00:46:42,850 --> 00:46:44,690
I think you'd be really good
at that.
680
00:46:47,610 --> 00:46:48,650
I don't know.
681
00:46:49,770 --> 00:46:51,650
It's more Adam's world.
Mm.
682
00:46:52,810 --> 00:46:54,010
Not any more.
683
00:46:55,690 --> 00:46:58,448
You can see how liberated he's been.
684
00:46:58,450 --> 00:47:01,528
He's carried that secret around
for so long.
685
00:47:01,530 --> 00:47:05,088
Well, he's stopped trying to
be all things to all men.
686
00:47:05,090 --> 00:47:08,010
And I'll tell you,
he loves beating himself up.
687
00:48:07,450 --> 00:48:10,968
Hi. I'm working on the case
of Wilfred Okoye.
688
00:48:10,970 --> 00:48:13,248
I was wondering if I could get
his microbiology results
689
00:48:13,250 --> 00:48:14,688
from his stay here.
690
00:48:14,690 --> 00:48:17,170
Date of birth is 9/7/66.
691
00:48:22,490 --> 00:48:25,088
I just need to, er,
speak to my supervisor.
692
00:48:25,090 --> 00:48:26,330
OK. Thank you.
693
00:49:04,210 --> 00:49:06,008
PHONE PINGS
694
00:49:06,010 --> 00:49:07,570
It's Adam.
695
00:49:09,770 --> 00:49:11,370
"We were wrong about everything.
696
00:49:13,450 --> 00:49:16,090
"At Cowley Institute. Come quickly."
What?
697
00:49:19,490 --> 00:49:21,368
What are we looking at?
698
00:49:21,370 --> 00:49:24,210
Wilfred's blood cultures.
Microbiology report.
699
00:49:27,050 --> 00:49:28,290
Hang on.
700
00:49:29,610 --> 00:49:33,328
The antibiotic sensitivities
have been reversed.
701
00:49:33,330 --> 00:49:34,808
Who's done that? Braithwaite?
702
00:49:34,810 --> 00:49:37,370
Couldn't be. These are from
the Cowley institute.
703
00:49:40,010 --> 00:49:41,610
Adam needs us. Come on.
704
00:50:11,250 --> 00:50:12,648
SHE SIGHS
705
00:50:12,650 --> 00:50:15,490
Oh, great. We were supposed to
go left back at the lights.
706
00:50:29,770 --> 00:50:31,210
CAR DOOR OPENS
707
00:50:32,850 --> 00:50:33,968
Dr Yuen?
708
00:50:33,970 --> 00:50:37,168
You know Emily Braithwaite
died yesterday?
709
00:50:37,170 --> 00:50:41,408
What? Uh, no. How did it happen?
710
00:50:41,410 --> 00:50:44,570
Unknown. Found dead in a house
that was bolted from the inside.
711
00:50:46,090 --> 00:50:48,650
Oh, look, an oxygen analyser.
712
00:50:50,050 --> 00:50:51,928
Do you always keep one of those
in your car?
713
00:50:51,930 --> 00:50:53,768
I use it for various things.
714
00:50:53,770 --> 00:50:57,048
So Emily died just as
you convinced us she was guilty.
715
00:50:57,050 --> 00:50:59,768
Her work was based on exploitation.
716
00:50:59,770 --> 00:51:01,968
Well, she can't deny that now,
can she?
717
00:51:01,970 --> 00:51:03,328
Well, whatever happened,
718
00:51:03,330 --> 00:51:06,608
I'm sure forensic science
will find the answer.
719
00:51:06,610 --> 00:51:10,088
Mm. Then I realised just how much
liquid nitrogen you go through here.
720
00:51:10,090 --> 00:51:12,090
Two deliveries in three days?
721
00:51:14,250 --> 00:51:17,648
I mean,
that is some evil genius stuff.
722
00:51:17,650 --> 00:51:19,808
Pretty quick and very clean.
723
00:51:19,810 --> 00:51:23,408
Except the pilot light in the boiler
went out at Braithwaite's house.
724
00:51:23,410 --> 00:51:24,810
Otherwise, the perfect crime.
725
00:51:26,050 --> 00:51:27,448
Are you insane?
726
00:51:27,450 --> 00:51:30,490
Oh, sorry. That's forensic science.
Get out.
727
00:51:34,770 --> 00:51:37,450
Braithwaite had Wilfred's
blood samples. She was onto you.
728
00:51:38,730 --> 00:51:40,528
My research is changing lives.
729
00:51:40,530 --> 00:51:42,248
She never made the crucial
breakthrough,
730
00:51:42,250 --> 00:51:43,808
but then again, neither did you.
731
00:51:43,810 --> 00:51:45,968
You reckon you'll crack it
any minute now, don't you?
732
00:51:45,970 --> 00:51:48,448
You just have to keep going,
keep blasting innocent men
733
00:51:48,450 --> 00:51:50,928
and women with poisonous drugs,
and then you'll get there.
734
00:51:50,930 --> 00:51:53,688
You know nothing. There's no
gene editing going on here.
735
00:51:53,690 --> 00:51:56,128
Your magic treatments are all
from stem cells that you get
736
00:51:56,130 --> 00:51:57,608
from killing people like Wilfred.
737
00:51:57,610 --> 00:52:01,288
When childhood cancer is
a thing of the past thanks to me,
738
00:52:01,290 --> 00:52:03,568
no-one will care.
739
00:52:03,570 --> 00:52:06,128
That's what it's all about,
isn't it?
740
00:52:06,130 --> 00:52:10,610
It's not about the money or
the power. It's about the prestige.
741
00:52:12,250 --> 00:52:14,848
So what are you going to do
about it, Adam?
742
00:52:14,850 --> 00:52:16,848
Mm? You're discredited.
743
00:52:16,850 --> 00:52:18,290
You're getting struck off.
744
00:52:19,530 --> 00:52:22,168
Of course I know!
745
00:52:22,170 --> 00:52:23,330
I know everything.
746
00:52:25,890 --> 00:52:28,290
You've no idea
who you're dealing with.
747
00:52:30,730 --> 00:52:31,970
Adam?
748
00:52:34,210 --> 00:52:35,250
Adam!
749
00:52:37,610 --> 00:52:41,168
PHONE RINGS
750
00:52:41,170 --> 00:52:43,688
Adam? What's happening?
751
00:52:43,690 --> 00:52:47,088
Cowley's the one exploiting Wilfred
and the rest of the donors.
752
00:52:47,090 --> 00:52:49,288
And he killed Braithwaite
with liquid nitrogen.
753
00:52:49,290 --> 00:52:51,408
He poured it in the vent
of her airtight house,
754
00:52:51,410 --> 00:52:54,888
turning it into a gas chamber.
She suffocated.
755
00:52:54,890 --> 00:52:57,888
Cowley did a deal with Rahul
to kill Wilfred during surgery.
756
00:52:57,890 --> 00:53:00,810
And when that failed, he attacked
Wilfred with the bacteria...
757
00:53:03,130 --> 00:53:05,368
..to make sure he switched
the micro reports
758
00:53:05,370 --> 00:53:07,368
so that the antibiotics
wouldn't work.
759
00:53:07,370 --> 00:53:09,250
ENGINE REVS
760
00:53:20,690 --> 00:53:21,890
Adam?
761
00:53:23,130 --> 00:53:24,450
Adam!
762
00:53:34,050 --> 00:53:35,490
HE COUGHS
763
00:53:43,970 --> 00:53:47,768
I'm sure that's Cowley.
Really? Call Cracknell.
764
00:53:47,770 --> 00:53:49,970
But...
Get after him. I'll find Adam.
765
00:53:58,570 --> 00:54:02,568
Yeah, I'm heading north
on Colbridge Road.
766
00:54:02,570 --> 00:54:05,328
It's a black Mercedes.
767
00:54:05,330 --> 00:54:06,688
Adam?
768
00:54:06,690 --> 00:54:07,808
Adam!
769
00:54:07,810 --> 00:54:09,170
Oh, Jesus.
770
00:54:12,530 --> 00:54:14,048
Ambulance.
771
00:54:14,050 --> 00:54:17,290
SIRENS WAIL
772
00:54:20,170 --> 00:54:22,408
Can you hear me? Adam?
773
00:54:22,410 --> 00:54:24,928
You took your time, mate.
774
00:54:24,930 --> 00:54:26,330
Come to take all the credit?
775
00:54:28,170 --> 00:54:29,450
Oh, man.
776
00:54:30,930 --> 00:54:33,648
The ambulance is on its way.
What happened?
777
00:54:33,650 --> 00:54:34,890
I messed up.
778
00:54:51,010 --> 00:54:52,170
You trusted me.
779
00:54:55,930 --> 00:54:57,010
That means a lot.
780
00:54:59,050 --> 00:55:01,528
Adam. Adam, stay with me.
781
00:55:01,530 --> 00:55:03,848
Adam. Come on, man. Stay with me.
Stay with me.
782
00:55:03,850 --> 00:55:05,130
Come on! Adam!
783
00:55:06,410 --> 00:55:07,450
Adam!
784
00:55:25,690 --> 00:55:29,490
SIREN WAILS
785
00:55:54,530 --> 00:55:55,570
Oh, God.
786
00:56:02,650 --> 00:56:04,050
Oh, no.
787
00:56:08,570 --> 00:56:12,290
SHE SOBS
788
00:56:36,170 --> 00:56:42,530
# Testator silens
789
00:56:45,370 --> 00:56:52,168
# Costestes e spiritu
790
00:56:52,170 --> 00:56:58,650
# Silencium. #
99873
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