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Would you like to inspect the original subtitles? These are the user uploaded subtitles that are being translated: 1 00:00:00,001 --> 00:00:05,384 Victim is Mr Arnie Rahul. Consultant surgeon. 48 years of age. 2 00:00:05,387 --> 00:00:08,215 Good reputation, though he's fallen out with a few people recently. 3 00:00:08,218 --> 00:00:10,817 {\an8}He was about to start an operation. He gets a phone call. 4 00:00:10,820 --> 00:00:13,050 Walks out, never comes back. 5 00:00:13,053 --> 00:00:16,090 Single puncture wound to the left chest wall. 6 00:00:17,290 --> 00:00:20,088 What's that in his hand? Looks like a syringe and needle. 7 00:00:20,090 --> 00:00:23,328 It's a Hickman line. A long-term vascular access device 8 00:00:23,330 --> 00:00:25,848 for people who need chemotherapy or blood transfusions. 9 00:00:25,850 --> 00:00:28,568 The assailant would have had extensive cross contamination 10 00:00:28,570 --> 00:00:30,048 with the victim's blood. 11 00:00:30,050 --> 00:00:32,208 Stick that in to a big artery and blood will flow out 12 00:00:32,210 --> 00:00:33,768 like a high-pressure hose. 13 00:00:33,770 --> 00:00:35,130 Simi Jacobs. 14 00:00:36,210 --> 00:00:37,570 He's denying everything. 15 00:00:38,650 --> 00:00:41,888 Simi Jacobs is not a match 16 00:00:41,890 --> 00:00:43,528 to the blood spatter at the scene. 17 00:00:43,530 --> 00:00:45,808 So, who is it? It's Wilfred Okoye. 18 00:00:45,810 --> 00:00:46,928 The patient? 19 00:00:46,930 --> 00:00:50,688 Arnie Rahul was murdered by a man who was under general anaesthetic 20 00:00:50,690 --> 00:00:52,088 in a different room? 21 00:00:52,090 --> 00:00:55,728 Blood alcohol level, three times the legal driving limit. 22 00:00:55,730 --> 00:00:58,048 You said he shouldn't be operating. 23 00:00:58,050 --> 00:01:00,048 Not after the Harry Fletcher incident. 24 00:01:00,050 --> 00:01:02,968 Arrested on the table during surgery last week. 25 00:01:02,970 --> 00:01:05,608 I want you to do the postmortem. 26 00:01:05,610 --> 00:01:07,808 Technically that would be a conflict of interest. 27 00:01:07,810 --> 00:01:11,088 Summarising postmortem examination, Harry Fletcher. 28 00:01:11,090 --> 00:01:13,008 What are you doing? My colleagues are here. 29 00:01:13,010 --> 00:01:15,968 Is that Emily Braithwaite? She's Adam's godmother. 30 00:01:15,970 --> 00:01:18,088 You'd think he might have mentioned it. 31 00:01:18,090 --> 00:01:20,608 Are you going to confront him? Not yet. 32 00:01:20,610 --> 00:01:23,048 Your original stem cell work was brilliant. 33 00:01:23,050 --> 00:01:26,928 But you tried and failed to turn it into a viable cancer treatment. 34 00:01:26,930 --> 00:01:29,488 Wilfred Okoye, still in the hospital. 35 00:01:29,490 --> 00:01:31,168 What's he going to know? 36 00:01:31,170 --> 00:01:34,128 You won't find out unless you ask him. 37 00:01:34,130 --> 00:01:37,008 Mr Fletcher died because of surgical error. 38 00:01:37,010 --> 00:01:40,568 Adam! You have no idea what you've done. 39 00:01:40,570 --> 00:01:43,088 When I applied for this job I falsified my CV, 40 00:01:43,090 --> 00:01:44,968 and Emily Braithwaite tried to use this 41 00:01:44,970 --> 00:01:47,248 fact to influence my findings in the Fletcher Case. 42 00:01:47,250 --> 00:01:48,928 Here's my letter of resignation. 43 00:01:48,930 --> 00:01:50,210 Effective immediately. 44 00:01:51,730 --> 00:01:57,770 {\an8}# Testator silens 45 00:02:00,290 --> 00:02:07,448 # Costestes e spiritu 46 00:02:07,450 --> 00:02:14,930 # Silencium 47 00:02:22,250 --> 00:02:28,050 # Testator silens. # 48 00:02:34,170 --> 00:02:36,770 DISTANT SIREN 49 00:02:39,570 --> 00:02:43,128 Wilfred Okoye, a Beninese farm worker, was admitted 50 00:02:43,130 --> 00:02:47,288 to St Jude's hospital for the treatment of leukaemia a week ago. 51 00:02:47,290 --> 00:02:50,688 Although he lost consciousness briefly during the attack 52 00:02:50,690 --> 00:02:54,368 on his life last night, he seems to have recovered with no ill effects. 53 00:02:54,370 --> 00:02:58,688 Awaiting toxicology from the syringe we believe was used in the attack. 54 00:02:58,690 --> 00:03:00,448 Prints? Fibres? 55 00:03:00,450 --> 00:03:02,728 Nothing conclusive. We're interviewing witnesses 56 00:03:02,730 --> 00:03:04,888 but no-one got a good look at the attacker. 57 00:03:04,890 --> 00:03:07,408 How come he's being treated here in the UK? 58 00:03:07,410 --> 00:03:11,250 It was set up by a charity, and then arranged through Rahul. 59 00:03:12,850 --> 00:03:17,088 Here is a man who has lived his entire life in Benin 60 00:03:17,090 --> 00:03:21,288 up until a week ago, and, according to our DNA evidence, 61 00:03:21,290 --> 00:03:25,570 murders his surgeon while under anaesthetic in a different room. 62 00:03:29,170 --> 00:03:34,768 Could the DNA at the murder scene been a contaminant or planted? 63 00:03:34,770 --> 00:03:37,528 No. The spatter patterns are too perfect. 64 00:03:37,530 --> 00:03:39,888 It came from someone who was in the room at the time. 65 00:03:39,890 --> 00:03:41,530 So, how do you explain it? 66 00:03:44,850 --> 00:03:47,928 How do we know Wilfred was anaesthetised? 67 00:03:47,930 --> 00:03:50,728 I mean, how do we know it was him? 68 00:03:50,730 --> 00:03:52,368 What, he's got an identical twin? 69 00:03:52,370 --> 00:03:53,848 Bit fantastical, Steve. 70 00:03:53,850 --> 00:03:55,688 I don't know. 71 00:03:55,690 --> 00:03:57,290 There's another explanation. 72 00:03:59,370 --> 00:04:01,488 DNA samples got mixed up. 73 00:04:01,490 --> 00:04:03,488 Ah! No way! 74 00:04:03,490 --> 00:04:06,688 Look, I'm just putting it out there. Mm-mn. We could run the test again. 75 00:04:06,690 --> 00:04:08,690 Those samples were handled correctly. 76 00:04:10,130 --> 00:04:12,330 Jack, shall we just run them again? 77 00:04:15,610 --> 00:04:17,370 Right, yep. Good. 78 00:04:18,610 --> 00:04:19,650 OK. 79 00:04:20,770 --> 00:04:22,770 Let me know when toxicology comes back. 80 00:04:31,090 --> 00:04:34,568 So, the samples got mixed up, did they? It's always possible. 81 00:04:34,570 --> 00:04:35,610 Mm-hm. 82 00:04:36,610 --> 00:04:39,850 You know who took the swab from Simi Jacobs. Adam. 83 00:04:41,290 --> 00:04:42,610 What are you suggesting? 84 00:04:44,650 --> 00:04:46,130 Just saying. 85 00:04:52,610 --> 00:04:54,888 PHONE RINGS 86 00:04:54,890 --> 00:04:56,688 VOICEMAIL: You have reached Dr Adam Yuen. 87 00:04:56,690 --> 00:04:58,288 I am unable to take your call. 88 00:04:58,290 --> 00:05:00,250 Please leave a message after the tone. 89 00:05:03,050 --> 00:05:05,608 Do you know what I don't understand? 90 00:05:05,610 --> 00:05:07,808 It was just a six-month placement, 91 00:05:07,810 --> 00:05:10,448 and his CV is impressive enough without it. 92 00:05:10,450 --> 00:05:13,610 So, why did he risk his career and lie about it? 93 00:05:16,570 --> 00:05:18,888 Has he lied about anything else? 94 00:05:18,890 --> 00:05:21,408 Everything else checks out. 95 00:05:21,410 --> 00:05:22,890 Are you sure about that? 96 00:05:26,330 --> 00:05:30,010 You have an injury over your left eye and a wound on your neck. 97 00:05:31,490 --> 00:05:33,450 How do you account for them, Simi? 98 00:05:34,690 --> 00:05:36,168 Yeah, I got mugged. 99 00:05:36,170 --> 00:05:38,610 A kid with a knife. Really? 100 00:05:40,370 --> 00:05:42,648 And did you report the assault? 101 00:05:42,650 --> 00:05:45,208 No. Why not? 102 00:05:45,210 --> 00:05:46,810 What, are you going to catch him? 103 00:05:48,970 --> 00:05:52,290 He's answered your questions, so unless you have other evidence? 104 00:06:05,730 --> 00:06:07,570 PHONE PINGS 105 00:06:15,530 --> 00:06:18,928 Tox results from the syringe used in the attack on Wilfred. 106 00:06:18,930 --> 00:06:20,690 Here we go. Let's have a look. 107 00:06:25,810 --> 00:06:28,010 That's it? Midazolam? 108 00:06:30,250 --> 00:06:32,448 That's a sedative, isn't it? 109 00:06:32,450 --> 00:06:33,490 Yeah. 110 00:06:35,650 --> 00:06:39,728 The full syringe would have had about five milligrams in it. 111 00:06:39,730 --> 00:06:40,850 That's not very much. 112 00:06:41,890 --> 00:06:45,968 So, either the assailant is incompetent, 113 00:06:45,970 --> 00:06:48,250 or this wasn't intended to kill him. 114 00:06:49,770 --> 00:06:52,648 So, what's the aim? 115 00:06:52,650 --> 00:06:54,290 Kidnapping? 116 00:06:57,050 --> 00:06:59,128 HE SIGHS 117 00:06:59,130 --> 00:07:01,248 The guy's already ill. 118 00:07:01,250 --> 00:07:03,568 You know... 119 00:07:03,570 --> 00:07:07,528 If someone wanted him dead, it's not going to be that hard, is it? 120 00:07:07,530 --> 00:07:08,850 He's got leukaemia. 121 00:07:10,690 --> 00:07:13,450 It would look like natural causes if he died of sepsis. 122 00:07:16,010 --> 00:07:19,010 Should I get that syringe tested again for bacteria? 123 00:07:25,770 --> 00:07:28,368 What's this about Mr Okoye being moved? 124 00:07:28,370 --> 00:07:29,808 It's for his own safety. 125 00:07:29,810 --> 00:07:32,488 To the Cowley Institute? And who's paying for that? 126 00:07:32,490 --> 00:07:35,448 Oh, I've been assured that they have all the facilities required, 127 00:07:35,450 --> 00:07:38,208 and they've offered to do the treatment free of charge. 128 00:07:38,210 --> 00:07:39,608 I will not allow it. 129 00:07:39,610 --> 00:07:42,850 Someone in your hospital is trying to kill Mr Okoye. 130 00:07:44,370 --> 00:07:47,530 Quite frankly, Dr Braithwaite, I don't need your permission. 131 00:08:00,130 --> 00:08:01,410 Haematology lab. 132 00:08:02,810 --> 00:08:04,808 Dr Braithwaite here. 133 00:08:04,810 --> 00:08:09,608 Wilfred Okoye, hospital number 1187266. 134 00:08:09,610 --> 00:08:12,128 I want all his stored blood and marrow samples sent 135 00:08:12,130 --> 00:08:13,770 to my office immediately. 136 00:08:40,930 --> 00:08:43,048 Finished! 137 00:08:43,050 --> 00:08:47,810 79 needles swabbed and ready to go. 138 00:08:49,370 --> 00:08:51,728 You've got to see this. 139 00:08:51,730 --> 00:08:53,728 Microbiology results from the syringe 140 00:08:53,730 --> 00:08:55,968 used in the attack on Wilfred. 141 00:08:55,970 --> 00:08:59,210 Turns out it is full of bacteria - E coli. 142 00:09:00,970 --> 00:09:03,128 Well, it was lying around on the floor. 143 00:09:03,130 --> 00:09:04,408 Could it be a contaminant? 144 00:09:04,410 --> 00:09:07,088 No. It's a pure growth - just one type of bug in there. 145 00:09:07,090 --> 00:09:08,968 If it was a contaminant you'd expect to see 146 00:09:08,970 --> 00:09:10,728 lots of different organisms. 147 00:09:10,730 --> 00:09:12,370 It's been created deliberately. 148 00:09:13,610 --> 00:09:17,368 So, what? The killer sneaks into Wilfred's room pretending 149 00:09:17,370 --> 00:09:20,928 to be a nurse, inoculates him with the bacteria, 150 00:09:20,930 --> 00:09:22,290 but adds a mild sedative... 151 00:09:24,490 --> 00:09:27,328 ..so that when the real nurse comes in with his medication, 152 00:09:27,330 --> 00:09:30,930 he's asleep and can't tell her that someone else has already been in. 153 00:09:32,130 --> 00:09:33,848 He gets sepsis, he dies. 154 00:09:33,850 --> 00:09:35,330 Looks like natural causes. 155 00:09:36,890 --> 00:09:38,608 I need to tell DI Cracknell. 156 00:09:38,610 --> 00:09:41,210 You need to tell the doctors looking after Wilfred. 157 00:09:45,370 --> 00:09:49,570 HEART MONITOR BEEPS 158 00:09:50,810 --> 00:09:53,010 HE BREATHES RAPIDLY 159 00:09:55,610 --> 00:09:58,250 ALARM SOUNDS 160 00:10:03,690 --> 00:10:05,570 HEART MONITOR BEEPS RAPIDLY 161 00:10:08,890 --> 00:10:11,010 HEART MONITOR FLATLINES 162 00:10:34,490 --> 00:10:37,408 It's as we expected - extensive peripheral oedema, 163 00:10:37,410 --> 00:10:40,728 multiple organ failure, consistent with sepsis. 164 00:10:40,730 --> 00:10:44,728 Yep. Toxicology shows only medications used for his treatment, 165 00:10:44,730 --> 00:10:48,208 antibiotics, ceftriaxone, gentamicin present 166 00:10:48,210 --> 00:10:49,928 in therapeutic concentrations. 167 00:10:49,930 --> 00:10:53,288 So, cause of death is consistent with deliberate inoculation 168 00:10:53,290 --> 00:10:56,168 of the culture of E coli, on a background 169 00:10:56,170 --> 00:10:59,568 of chemotherapy-induced immune compromise. 170 00:10:59,570 --> 00:11:02,688 Well, we've got no other leads on his attacker at present. 171 00:11:02,690 --> 00:11:05,088 We're liaising with the Beninese Consulate to inform 172 00:11:05,090 --> 00:11:07,688 the family of the deceased. 173 00:11:07,690 --> 00:11:13,048 DNA says Wilfred Okoye was guilty of Rahul's murder, 174 00:11:13,050 --> 00:11:15,410 but being unconscious, had the perfect alibi. 175 00:11:17,090 --> 00:11:20,088 When a murder suspect gets murdered, what does that mean? 176 00:11:20,090 --> 00:11:21,808 Framed by the real murderer? 177 00:11:21,810 --> 00:11:24,410 Why would you frame someone with the perfect alibi? 178 00:11:30,610 --> 00:11:32,808 Simi Jacobs. 179 00:11:32,810 --> 00:11:34,488 What's his home address? 180 00:11:34,490 --> 00:11:35,530 Erm... 181 00:11:37,370 --> 00:11:41,128 Let's see. Flat 32, Bardwell House, Lincoln Street. 182 00:11:41,130 --> 00:11:44,768 Thought so. Okoye and Jacobs have been living together. 183 00:11:44,770 --> 00:11:47,968 Simi Jacobs has already been released, guv. 184 00:11:47,970 --> 00:11:50,568 What? Yeah. Lack of forensics. 185 00:11:50,570 --> 00:11:52,048 All right. 186 00:11:52,050 --> 00:11:54,050 Might I suggest we pick him up again? 187 00:12:01,210 --> 00:12:03,288 It still doesn't get us anywhere. 188 00:12:03,290 --> 00:12:05,048 It doesn't explain the DNA. 189 00:12:05,050 --> 00:12:07,448 And Simi was in custody when Wilfred was attacked, 190 00:12:07,450 --> 00:12:08,848 so it doesn't even explain that. 191 00:12:08,850 --> 00:12:11,330 We're just going round in circles. Yep. 192 00:12:22,210 --> 00:12:25,368 When he was interviewed, Wilfred said his leukaemia 193 00:12:25,370 --> 00:12:28,050 was common in his region. 194 00:12:30,690 --> 00:12:32,050 Doesn't sound right to me. 195 00:12:47,010 --> 00:12:48,888 PHONE RINGS 196 00:12:48,890 --> 00:12:50,928 VOICEMAIL: You have reached Dr Adam Yuen. 197 00:12:50,930 --> 00:12:52,368 I am unable to take your call. 198 00:12:52,370 --> 00:12:54,330 Please leave a message after the tone. 199 00:12:57,250 --> 00:12:59,208 Wait there. He's not in, guv. 200 00:12:59,210 --> 00:13:00,888 And the neighbours haven't seen him. 201 00:13:00,890 --> 00:13:03,168 He's not been seen back at work at the hospital either. 202 00:13:03,170 --> 00:13:06,048 You two stick around in case he comes back. 203 00:13:06,050 --> 00:13:09,290 I'm sorry, guv. I should have spotted the address. 204 00:13:11,090 --> 00:13:13,048 Don't worry about it. 205 00:13:13,050 --> 00:13:16,210 At least you didn't wrongly arrest a bereaved cancer patient. 206 00:13:20,570 --> 00:13:22,090 I'll do that next time. 207 00:13:26,410 --> 00:13:27,450 Bye. 208 00:13:32,410 --> 00:13:34,650 Nine missed calls. You're very persistent. 209 00:13:37,650 --> 00:13:39,290 I didn't want to end it like that. 210 00:13:41,930 --> 00:13:43,610 Can I help? 211 00:13:54,610 --> 00:13:57,648 You should have told me that Emily Braithwaite is your godmother. 212 00:13:57,650 --> 00:13:59,568 Some godmother. 213 00:13:59,570 --> 00:14:02,168 No doubt you've received the incriminating evidence about me. 214 00:14:02,170 --> 00:14:03,370 What evidence? 215 00:14:05,010 --> 00:14:07,768 She never sent it. I should have guessed. 216 00:14:07,770 --> 00:14:10,928 If she tried to blackmail you, then we'll make her answer for that. 217 00:14:10,930 --> 00:14:12,050 She's far too clever. 218 00:14:14,010 --> 00:14:16,930 Why do I think there's more to this than you're telling me? 219 00:14:18,650 --> 00:14:20,888 No, I just lied to advance my career. 220 00:14:20,890 --> 00:14:23,930 Really? Just to say you had a fellowship. Why would you do that? 221 00:14:29,490 --> 00:14:31,008 My family are all doctors. 222 00:14:31,010 --> 00:14:33,008 I was always going to be a surgeon. 223 00:14:33,010 --> 00:14:34,730 It was more or less decided for me. 224 00:14:36,610 --> 00:14:39,728 Final year of medical school, I was walking to uni 225 00:14:39,730 --> 00:14:42,968 and a cyclist is knocked off her bike, right in front of me. 226 00:14:42,970 --> 00:14:44,808 Now, I was a keen student. 227 00:14:44,810 --> 00:14:47,888 I used to carry a first aid kit around with me. 228 00:14:47,890 --> 00:14:51,568 If I'm honest, I was always waiting for something like this. 229 00:14:51,570 --> 00:14:54,968 When I think about that it's actually what I'm most ashamed of. 230 00:14:54,970 --> 00:14:57,248 She had facial injuries. 231 00:14:57,250 --> 00:14:59,888 Heavy, laboured breathing. She was losing consciousness fast. 232 00:14:59,890 --> 00:15:01,808 So, I thought, "She's suffocating. 233 00:15:01,810 --> 00:15:06,168 "She needs a surgical airway, a cricothyroidotomy." 234 00:15:06,170 --> 00:15:07,528 So, I made my incision. 235 00:15:07,530 --> 00:15:10,048 Something that I had practised on mannequins. 236 00:15:10,050 --> 00:15:14,208 What I didn't know is that she had an abnormal anatomy - 237 00:15:14,210 --> 00:15:17,650 an aberrant subclavian artery, looping high in the neck. 238 00:15:18,810 --> 00:15:22,128 It's present in 1% of people and 0% of mannequins. 239 00:15:22,130 --> 00:15:24,530 How could you have known? It was a bloodbath. 240 00:15:32,210 --> 00:15:35,048 The artery retracted back into her chest. 241 00:15:35,050 --> 00:15:37,648 There was nothing we could do to save her. 242 00:15:37,650 --> 00:15:39,810 She bled to death in minutes. 243 00:15:44,250 --> 00:15:46,770 My father was furious. 244 00:15:48,450 --> 00:15:51,128 Not because I stupidly tried a tracheostomy 245 00:15:51,130 --> 00:15:52,890 and killed an innocent young girl. 246 00:15:54,490 --> 00:15:58,290 But because I didn't study hard enough to do it competently. 247 00:16:00,530 --> 00:16:05,008 So, he used his influence and arranged for my fellowship 248 00:16:05,010 --> 00:16:06,770 as cover. For what? 249 00:16:10,690 --> 00:16:12,170 For my absence. 250 00:16:15,490 --> 00:16:18,770 It took months of therapy before I could even leave the house. 251 00:16:27,530 --> 00:16:31,128 The irony in all of this is that the one who helped me out 252 00:16:31,130 --> 00:16:32,810 the most was Emily Braithwaite. 253 00:16:34,250 --> 00:16:36,850 She visited me more often than my parents. 254 00:16:39,890 --> 00:16:41,130 She understood. 255 00:16:44,050 --> 00:16:46,370 But there was no way I was going to be a surgeon. 256 00:16:50,050 --> 00:16:52,688 So, I decided to choose pathology, 257 00:16:52,690 --> 00:16:56,570 and a false narrative was created as to why I made the switch. 258 00:16:58,250 --> 00:17:01,168 When you start lying, 259 00:17:01,170 --> 00:17:03,450 you have to keep lying. 260 00:17:23,250 --> 00:17:25,288 Jack. Mm? I need to talk to you. 261 00:17:25,290 --> 00:17:26,650 Sure, what's up...? 262 00:17:29,170 --> 00:17:30,568 Hi. 263 00:17:30,570 --> 00:17:31,690 Are you kidding me? 264 00:17:35,050 --> 00:17:37,408 He doesn't work here any more because he lied to us, do you 265 00:17:37,410 --> 00:17:40,128 remember? Do you remember that? Adam's got a theory about Wilfred. 266 00:17:40,130 --> 00:17:41,688 Oh, right. Just hear him out. 267 00:17:41,690 --> 00:17:45,688 So, um, I just have to trust him now? 268 00:17:45,690 --> 00:17:47,690 No, you've got to trust me. 269 00:17:51,570 --> 00:17:52,690 Think about it. 270 00:17:54,010 --> 00:17:56,648 Why would someone want Wilfred dead? 271 00:17:56,650 --> 00:17:58,928 What did he know that was such a threat that someone 272 00:17:58,930 --> 00:17:59,970 had to kill him? 273 00:18:01,610 --> 00:18:05,048 Wilfred was being treated for acute myeloid leukaemia. 274 00:18:05,050 --> 00:18:06,288 That's rare. 275 00:18:06,290 --> 00:18:08,808 Remember, he said there were lots of other cases in his small 276 00:18:08,810 --> 00:18:11,008 village in Africa. 277 00:18:11,010 --> 00:18:13,728 What if Wilfred wasn't killed because of what he knew? 278 00:18:13,730 --> 00:18:14,888 Don't follow. 279 00:18:14,890 --> 00:18:16,690 Wilfred wasn't the witness. 280 00:18:18,850 --> 00:18:20,170 He was the evidence. 281 00:18:23,650 --> 00:18:26,048 This is a trephine biopsy of the bone marrow. 282 00:18:26,050 --> 00:18:29,768 We take a thin core of bone with marrow cells in it. 283 00:18:29,770 --> 00:18:32,090 I've already taken an aspirate of the fluids. 284 00:18:43,330 --> 00:18:46,808 So, the question is, why would so many people from one place 285 00:18:46,810 --> 00:18:48,210 all get leukaemia? 286 00:18:49,450 --> 00:18:51,288 And that's going to tell you, is it? 287 00:18:51,290 --> 00:18:53,128 To be honest, I've never done this before. 288 00:18:53,130 --> 00:18:55,128 Not postmortem, anyway. 289 00:18:55,130 --> 00:18:58,290 But you know what? It's crazy enough for it to work. Mm-mm. 290 00:19:10,050 --> 00:19:11,090 Thanks. 291 00:19:13,130 --> 00:19:16,490 Oh, look. Here's a billion DNA results from the needles. 292 00:19:18,090 --> 00:19:21,048 Want to give me a hand going through these? 293 00:19:21,050 --> 00:19:22,210 Didn't think so. 294 00:19:40,210 --> 00:19:42,890 Nikki? The slide's ready when you want to have a look. 295 00:19:51,290 --> 00:19:53,928 Good yield of cells. More than I expected. 296 00:19:53,930 --> 00:19:56,368 Definitely acute myeloid leukaemia. 297 00:19:56,370 --> 00:19:59,848 It's not typical. Looks more like secondary AML. 298 00:19:59,850 --> 00:20:02,568 Secondary to what? A toxin of some sort. 299 00:20:02,570 --> 00:20:04,608 Some industrial chemical, for example, 300 00:20:04,610 --> 00:20:08,608 or chemotherapy for a different cancer. 301 00:20:08,610 --> 00:20:11,488 Right. And that can occur years after the original exposure. 302 00:20:11,490 --> 00:20:13,488 Decades, in some cases. 303 00:20:13,490 --> 00:20:17,050 So, there may be other victims, all exposed to the same thing? 304 00:20:19,090 --> 00:20:20,450 Makes sense. 305 00:20:22,130 --> 00:20:26,170 BUZZING 306 00:20:39,330 --> 00:20:40,488 Can I help you? 307 00:20:40,490 --> 00:20:42,528 They told me Wilfred is here. 308 00:20:42,530 --> 00:20:44,368 Can I see him, yeah? 309 00:20:44,370 --> 00:20:46,570 Er, you are? Family. 310 00:20:48,850 --> 00:20:50,408 Do you want to take a seat? 311 00:20:50,410 --> 00:20:53,610 Will I be able to sit with him for a bit or...? I'll just check. 312 00:21:03,090 --> 00:21:05,408 I've found Rahul's murder weapon. 313 00:21:05,410 --> 00:21:09,168 One DNA profile matching Rahul, one matching Wilfred, 314 00:21:09,170 --> 00:21:10,928 just like we found at the scene. 315 00:21:10,930 --> 00:21:12,930 But there's a third profile. 316 00:21:14,690 --> 00:21:16,808 Yep. Simi Jacobs. 317 00:21:16,810 --> 00:21:18,848 Simi? He's here! 318 00:21:18,850 --> 00:21:21,770 What do you mean he's here? He wants to see Wilfred's body. 319 00:21:36,850 --> 00:21:39,648 This places Simi at the scene of Rahul's murder. 320 00:21:39,650 --> 00:21:41,648 We need to keep him here. 321 00:21:41,650 --> 00:21:43,250 Call DI Cracknell. 322 00:21:47,130 --> 00:21:49,648 So, hang on. Simi Jacobs just turned up at the lab. 323 00:21:49,650 --> 00:21:51,808 One needle injected into three people. 324 00:21:51,810 --> 00:21:53,248 Better get down here. 325 00:21:53,250 --> 00:21:55,248 Simi had a puncture wound to his neck. 326 00:21:55,250 --> 00:21:58,208 Rahul was stabbed in the chest, but Wilfred? 327 00:21:58,210 --> 00:22:00,008 And if Simi got in a fight with Rahul, 328 00:22:00,010 --> 00:22:01,968 why is Wilfred's blood spattered? 329 00:22:01,970 --> 00:22:04,648 Wilfred would have to have been in the room as well. 330 00:22:04,650 --> 00:22:06,650 Maybe he was. Genetically speaking. 331 00:22:07,970 --> 00:22:10,488 What if that needle only stabbed two people? 332 00:22:10,490 --> 00:22:13,368 Then one of them has two different types of DNA. Exactly. 333 00:22:13,370 --> 00:22:14,928 Huh? No, for that to work, it would 334 00:22:14,930 --> 00:22:17,648 mean Simi's walking around with Wilfred's blood inside him. 335 00:22:17,650 --> 00:22:19,530 That's ridiculous. Is it? 336 00:22:21,650 --> 00:22:24,808 Bone marrow transplant. And Wilfred was the donor. 337 00:22:24,810 --> 00:22:28,610 So, Simi's blood has Wilfred's DNA. 338 00:22:36,130 --> 00:22:37,850 Do you want to come this way? Yeah. 339 00:22:42,290 --> 00:22:43,370 Just there. 340 00:22:46,450 --> 00:22:49,208 Can I get you a tea? A glass of water or...? 341 00:22:49,210 --> 00:22:51,088 Oh, no, no! 342 00:22:51,090 --> 00:22:52,130 Thanks. 343 00:22:55,090 --> 00:22:57,488 You said that Wilfred was family? 344 00:22:57,490 --> 00:22:59,248 That's right. 345 00:22:59,250 --> 00:23:00,890 Was he a close relative? 346 00:23:02,530 --> 00:23:04,848 You ask a lot of questions. 347 00:23:04,850 --> 00:23:06,530 Remember me? 348 00:23:08,330 --> 00:23:10,448 I examined you at the station. 349 00:23:10,450 --> 00:23:11,768 I saw a scar on your chest. 350 00:23:11,770 --> 00:23:13,410 That's a Hickman line scar. 351 00:23:15,010 --> 00:23:17,330 Did you have a bone marrow transplant as a kid? 352 00:23:18,770 --> 00:23:20,568 Yeah, I'm going to go. 353 00:23:20,570 --> 00:23:23,410 Simi, we found your blood at the scene of Rahul's murder. 354 00:23:25,410 --> 00:23:26,650 Did you kill him? 355 00:23:29,490 --> 00:23:34,168 No, no, no. He... He came at me! He was insane! 356 00:23:34,170 --> 00:23:35,490 It was an accident! 357 00:23:39,570 --> 00:23:41,290 I just wanted to protect Wilfred. 358 00:23:43,450 --> 00:23:46,248 Wilfred saved my life when I was a kid. 359 00:23:46,250 --> 00:23:49,288 But you know what? He could only do that because he was a match. 360 00:23:49,290 --> 00:23:52,168 People have transplants from their brothers or mothers or whatever 361 00:23:52,170 --> 00:23:55,090 because they're a match. I had no-one. 362 00:23:56,490 --> 00:23:59,568 How did you find him? There's this charity attached to our church. 363 00:23:59,570 --> 00:24:01,570 They helped us get the transplant records. 364 00:24:03,570 --> 00:24:05,290 Only it turns out Wilfred was sick. 365 00:24:06,490 --> 00:24:08,688 Were there others? Yeah. 366 00:24:08,690 --> 00:24:11,730 I mean, loads of people in his village died from the same thing. 367 00:24:13,730 --> 00:24:15,370 We found Wilfred in time. 368 00:24:17,930 --> 00:24:19,370 So we thought. 369 00:24:21,290 --> 00:24:23,448 What? 370 00:24:23,450 --> 00:24:25,170 You're not going to let me see him? 371 00:24:29,250 --> 00:24:31,968 Simi. 372 00:24:31,970 --> 00:24:33,210 There he is. 373 00:24:53,730 --> 00:24:57,168 Ah, afternoon! Present from DI Cracknell - 374 00:24:57,170 --> 00:25:00,008 all the rubbish from Simi Jacobs' address. 375 00:25:00,010 --> 00:25:01,488 Thought you might want to take a look 376 00:25:01,490 --> 00:25:03,288 in case you find anything relevant. 377 00:25:03,290 --> 00:25:07,648 Joy. Can I introduce Reverend Kanu? You've already met Jack. 378 00:25:07,650 --> 00:25:11,688 This is Dr Nikki Alexander and Dr Adam Yuen. Hello. 379 00:25:11,690 --> 00:25:15,088 Reverend Kanu runs the charitable organisation that was responsible 380 00:25:15,090 --> 00:25:16,968 for bringing Wilfred to the UK. 381 00:25:16,970 --> 00:25:18,768 I have some photos from our trip. 382 00:25:18,770 --> 00:25:22,488 Sergeant Galloway thinks they might help you. Thank you. 383 00:25:22,490 --> 00:25:24,930 I have to warn you, they're not pretty. 384 00:25:28,090 --> 00:25:30,330 Tell me how Mr Okoye came to be here. 385 00:25:31,930 --> 00:25:36,128 My church runs a charity that helps arrange treatment in the UK. 386 00:25:36,130 --> 00:25:38,930 They raise money, get doctors to volunteer, whatever. 387 00:25:40,410 --> 00:25:42,768 Wilfred's case was kind of special. 388 00:25:42,770 --> 00:25:46,448 I mean, he helped me years ago, and now he needed my help. 389 00:25:46,450 --> 00:25:48,768 The local newspaper picked up the story, it got a lot 390 00:25:48,770 --> 00:25:52,168 of publicity. So, the hospital agreed to treat him. 391 00:25:52,170 --> 00:25:54,650 And he stayed at your flat? Yeah. 392 00:25:56,890 --> 00:25:59,768 Nobody told me he don't speak English. 393 00:25:59,770 --> 00:26:02,608 I couldn't tell him anything. 394 00:26:02,610 --> 00:26:05,850 He didn't know who I was, what he did for me. 395 00:26:08,210 --> 00:26:11,010 Then I learnt that he's under the care of this Rahul guy. 396 00:26:12,850 --> 00:26:17,648 I have travelled widely in Africa as part of my ministry, 397 00:26:17,650 --> 00:26:22,530 and yet nothing could have prepared me for what we found in Bwendora. 398 00:26:25,410 --> 00:26:28,690 The town is remote, even by African standards. 399 00:26:30,170 --> 00:26:33,408 There is only very basic health care. 400 00:26:33,410 --> 00:26:36,210 It became clear there was a lot of sickness. 401 00:26:38,010 --> 00:26:40,810 This man died within hours of our arrival. 402 00:26:41,970 --> 00:26:46,408 The illness causes bleeding and rashes. Fever sometimes. 403 00:26:46,410 --> 00:26:48,568 What do the people think it's caused by? 404 00:26:48,570 --> 00:26:51,688 There's a large pesticide factory in the town. 405 00:26:51,690 --> 00:26:54,848 Many people think the water has been contaminated. 406 00:26:54,850 --> 00:26:57,808 They organised protests. 407 00:26:57,810 --> 00:27:00,768 People think there has been a cover-up. 408 00:27:00,770 --> 00:27:03,170 But the factory provides a lot of employment. 409 00:27:04,530 --> 00:27:08,248 It is a very divisive issue. 410 00:27:08,250 --> 00:27:12,968 The illness has ripped the heart out of the community. 411 00:27:12,970 --> 00:27:16,008 There are very few families it has left untouched. 412 00:27:16,010 --> 00:27:17,968 And they've had no outside help? 413 00:27:17,970 --> 00:27:21,208 There is one western charity which runs a clinic, 414 00:27:21,210 --> 00:27:23,090 but they only visit every few months. 415 00:27:25,730 --> 00:27:26,930 Some charity. 416 00:27:29,730 --> 00:27:31,888 Oh, Lord. 417 00:27:31,890 --> 00:27:33,810 Enlighten our minds with your truth. 418 00:27:36,130 --> 00:27:39,290 Give us the strength and the wisdom to seek justice. 419 00:27:40,970 --> 00:27:44,770 Shine your everlasting light into our darkness. 420 00:27:47,130 --> 00:27:50,528 There's a lot of talk about Rahul, all around the hospital. 421 00:27:50,530 --> 00:27:52,968 How the hospital is protecting him. 422 00:27:52,970 --> 00:27:56,408 How he messed up an operation and no-one wants to work with him. 423 00:27:56,410 --> 00:27:59,128 And you thought he shouldn't operate on Wilfred. 424 00:27:59,130 --> 00:28:03,128 The night before, I heard him arguing with this woman, 425 00:28:03,130 --> 00:28:05,248 Dr Braithwaite. 426 00:28:05,250 --> 00:28:07,328 She told Rahul not to do the operation 427 00:28:07,330 --> 00:28:10,128 and he just told her that she couldn't stop him. 428 00:28:10,130 --> 00:28:12,648 The bag of rubbish that we found at your home address. 429 00:28:12,650 --> 00:28:14,648 Was it from one of the offices? 430 00:28:14,650 --> 00:28:16,090 Yeah. Which one? 431 00:28:17,170 --> 00:28:18,568 All of them. 432 00:28:18,570 --> 00:28:21,008 I was looking for something, anything, 433 00:28:21,010 --> 00:28:22,848 I could use against Rahul. 434 00:28:22,850 --> 00:28:25,328 And on the morning of the operation? 435 00:28:25,330 --> 00:28:28,288 I saw Wilfred getting prepared for theatre and I panicked. 436 00:28:28,290 --> 00:28:30,048 I phoned Rahul. 437 00:28:30,050 --> 00:28:31,528 What did you say? 438 00:28:31,530 --> 00:28:33,888 I told him I had some information on him. 439 00:28:33,890 --> 00:28:38,008 I thought I could threaten to reveal what I knew if he did the operation. 440 00:28:38,010 --> 00:28:39,210 What information? 441 00:28:41,730 --> 00:28:44,810 I was bluffing. But I had to stop him. 442 00:28:48,010 --> 00:28:49,770 Well, you certainly managed that. 443 00:29:04,970 --> 00:29:06,448 How's it going? 444 00:29:06,450 --> 00:29:09,850 Oh, I'm in my element rummaging through the trash. You know me. 445 00:29:10,930 --> 00:29:13,288 Nothing much here, apart from a criminally lax attitude 446 00:29:13,290 --> 00:29:14,330 to recycling. 447 00:29:16,530 --> 00:29:18,528 Adam's still here, is he? 448 00:29:18,530 --> 00:29:20,528 We wouldn't have got this far without him. 449 00:29:20,530 --> 00:29:22,170 I want to trust him. 450 00:29:24,570 --> 00:29:25,690 What's that? 451 00:29:30,610 --> 00:29:31,650 Oh, my God. 452 00:29:33,130 --> 00:29:37,728 This was in that rubbish bag you found at Simi Jacobs' place. 453 00:29:37,730 --> 00:29:40,848 It's Harry Fletcher's ECG, taken the day of his operation. 454 00:29:40,850 --> 00:29:42,128 It's normal. 455 00:29:42,130 --> 00:29:45,968 And this is the ECG that appeared in Fletcher's notes. 456 00:29:45,970 --> 00:29:49,048 Same date and time, but grossly abnormal. 457 00:29:49,050 --> 00:29:52,848 We believe they were switched to deflect blame from Rahul 458 00:29:52,850 --> 00:29:55,208 after the operation went wrong. 459 00:29:55,210 --> 00:29:57,168 So, there was a cover-up? 460 00:29:57,170 --> 00:29:59,888 Well, what's this got to do with the murder investigation? 461 00:29:59,890 --> 00:30:02,848 Yeah, Simi Jacobs admitted to the attack on Arnie Rahul. 462 00:30:02,850 --> 00:30:05,728 I mean, he claims it was an accident as a result of self-defence. 463 00:30:05,730 --> 00:30:07,448 That fits with the crime scene findings. 464 00:30:07,450 --> 00:30:09,808 So, how does this transplant fit in? 465 00:30:09,810 --> 00:30:12,568 Well, Simi was born with sickle cell disease, 466 00:30:12,570 --> 00:30:16,728 and was treated with a bone marrow transplant at St Jude's as a child. 467 00:30:16,730 --> 00:30:19,528 Wilfred donated his stem cells for Simi's transplant. 468 00:30:19,530 --> 00:30:21,888 20 years later, Wilfred gets leukaemia. 469 00:30:21,890 --> 00:30:23,768 We don't think this is a coincidence. 470 00:30:23,770 --> 00:30:27,008 He had a type of leukaemia that can be caused by over-exposure 471 00:30:27,010 --> 00:30:28,288 to certain drugs. 472 00:30:28,290 --> 00:30:31,688 There's a technique known as mobilisation, 473 00:30:31,690 --> 00:30:34,568 which is designed to increase production of stem cells. 474 00:30:34,570 --> 00:30:38,768 Normally, stem cell donation involves giving a perfectly safe 475 00:30:38,770 --> 00:30:40,288 bone marrow stimulant. 476 00:30:40,290 --> 00:30:45,208 But whoever did this also gave Wilfred high levels of chemotherapy, 477 00:30:45,210 --> 00:30:47,048 and did so repeatedly. 478 00:30:47,050 --> 00:30:49,408 They gave chemo? To a volunteer? 479 00:30:49,410 --> 00:30:51,568 To yield even more stem cells. 480 00:30:51,570 --> 00:30:53,808 What for? More transplants? 481 00:30:53,810 --> 00:30:58,728 Stem cells have the ability to develop into any type of body cell. 482 00:30:58,730 --> 00:31:00,688 Brain, heart, blood - you name it. 483 00:31:00,690 --> 00:31:03,008 So there's a huge range of potential therapies 484 00:31:03,010 --> 00:31:06,568 in which they can be used, one of which is transplantation. 485 00:31:06,570 --> 00:31:11,248 About ten years ago, Braithwaite and her team identified stem cells 486 00:31:11,250 --> 00:31:13,448 that were very special indeed, 487 00:31:13,450 --> 00:31:17,008 capable of being turned into what are called killer T-cells, 488 00:31:17,010 --> 00:31:21,088 part of the immune system, which can be made to attack malignant tumours. 489 00:31:21,090 --> 00:31:23,448 The potential for this discovery was enormous. 490 00:31:23,450 --> 00:31:25,768 These magic cells all had the same gene, 491 00:31:25,770 --> 00:31:30,088 a gene we think might be common in Wilfred's town. 492 00:31:30,090 --> 00:31:33,888 They went looking for transplant donors to treat people like Simi, 493 00:31:33,890 --> 00:31:36,688 but what they discovered was something much bigger, 494 00:31:36,690 --> 00:31:38,808 so they went back for more, and more. 495 00:31:38,810 --> 00:31:41,448 Basically they were flogging him for every last stem cell 496 00:31:41,450 --> 00:31:43,848 he could produce. Him and all the others. 497 00:31:43,850 --> 00:31:46,168 Wilfred's town was basically a stem cell farm. 498 00:31:46,170 --> 00:31:49,608 Can you prove Wilfred was given the stimulating drugs? 499 00:31:49,610 --> 00:31:52,810 It may be possible, but that's way out of my league. 500 00:31:54,530 --> 00:31:56,410 Sounds like we need a second opinion. 501 00:32:16,410 --> 00:32:17,728 Thank you, Professor. 502 00:32:17,730 --> 00:32:19,368 Not at all. It's very good to see you. 503 00:32:19,370 --> 00:32:20,890 Thank you. Oh, he's away! 504 00:32:22,730 --> 00:32:26,168 Adam, hello again. Hello. This is Dr Nikki Alexander. 505 00:32:26,170 --> 00:32:28,528 Hello. How do you do? And you've already met DI Cracknell. 506 00:32:28,530 --> 00:32:30,130 Yes, of course. This way. 507 00:32:31,090 --> 00:32:32,768 That was Alfie. 508 00:32:32,770 --> 00:32:36,888 He's one of our early trial patients - osteosarcoma. 509 00:32:36,890 --> 00:32:39,008 When he was referred to us, he was in a hospice 510 00:32:39,010 --> 00:32:42,568 on palliative treatment, expected to die within weeks. 511 00:32:42,570 --> 00:32:44,970 Please. That was two years ago. 512 00:32:46,370 --> 00:32:47,730 He's now disease-free. 513 00:32:50,490 --> 00:32:53,968 We wanted to show you some bone marrow samples from Mr Okoye. 514 00:32:53,970 --> 00:32:56,210 He was moved from St Jude's to be treated here. 515 00:33:04,690 --> 00:33:06,648 Hmm. 516 00:33:06,650 --> 00:33:08,290 Secondary leukaemia. 517 00:33:11,170 --> 00:33:12,648 They look very unusual. 518 00:33:12,650 --> 00:33:15,488 Mr Okoye was a stem cell donor. 519 00:33:15,490 --> 00:33:17,208 Was he? 520 00:33:17,210 --> 00:33:20,448 We were wondering if it might be stimulated. 521 00:33:20,450 --> 00:33:21,810 You mean Cyclo-G? 522 00:33:23,130 --> 00:33:24,608 Oh, dear. 523 00:33:24,610 --> 00:33:28,168 Yes, it's possible. 524 00:33:28,170 --> 00:33:31,088 Is there any way we can confirm it? 525 00:33:31,090 --> 00:33:33,968 You would need to look into the genetics of his blood cells. 526 00:33:33,970 --> 00:33:36,088 There are some telltale signs. 527 00:33:36,090 --> 00:33:39,448 We have several world experts in cytogenetics here. 528 00:33:39,450 --> 00:33:41,688 They'd be happy to help. 529 00:33:41,690 --> 00:33:44,688 Your cancer therapies are based on Braithwaite's stem cell research, 530 00:33:44,690 --> 00:33:48,808 are they not? Yes. Yes. I've never denied it. 531 00:33:48,810 --> 00:33:51,490 Hers was an extraordinary piece of work. 532 00:33:52,650 --> 00:33:55,728 She tried for years to turn it into a practical treatment, 533 00:33:55,730 --> 00:34:00,328 but, in the end, she was stumped by the obvious problem. 534 00:34:00,330 --> 00:34:02,208 The limited supply of donors. 535 00:34:02,210 --> 00:34:03,488 Precisely. 536 00:34:03,490 --> 00:34:07,890 So, what we brought to the party is called gene editing. 537 00:34:09,130 --> 00:34:12,768 We found a way of inserting the special gene 538 00:34:12,770 --> 00:34:15,170 into any old stem cell, and the result is... 539 00:34:16,250 --> 00:34:17,730 Well, you met Alfie. 540 00:34:18,810 --> 00:34:21,290 What is your relationship to Emily Braithwaite? 541 00:34:22,890 --> 00:34:24,408 Yes. 542 00:34:24,410 --> 00:34:27,568 Well, I suppose you'd say we're rivals. 543 00:34:27,570 --> 00:34:31,448 She's never forgiven me for succeeding where she failed. 544 00:34:31,450 --> 00:34:35,448 But I'm afraid her star has been waning for some time. 545 00:34:35,450 --> 00:34:36,890 What makes you say that? 546 00:34:39,170 --> 00:34:41,168 She came to ask for my help. 547 00:34:41,170 --> 00:34:44,888 Believe me, that alone suggests desperation. 548 00:34:44,890 --> 00:34:48,608 She had just lost a very large research grant. 549 00:34:48,610 --> 00:34:51,168 Is it possible that Braithwaite poisoned Mr Okoye 550 00:34:51,170 --> 00:34:54,528 and everyone else in his town to get more stem cells? 551 00:34:54,530 --> 00:34:57,248 That's a serious accusation. 552 00:34:57,250 --> 00:34:59,088 Everything's falling apart. 553 00:34:59,090 --> 00:35:01,488 So, like a gambler, she risks more and more, 554 00:35:01,490 --> 00:35:04,170 desperate for that big win to get herself back on top. 555 00:35:14,050 --> 00:35:19,650 THEY CONFER 556 00:35:22,810 --> 00:35:24,450 PHONE PINGS 557 00:35:59,650 --> 00:36:01,250 Now what? Excuse me? 558 00:36:02,410 --> 00:36:05,648 You do realise my career is over? And that's my fault? 559 00:36:05,650 --> 00:36:07,528 There's got to be a way out of this. 560 00:36:07,530 --> 00:36:08,850 You owe me that at least. 561 00:36:10,130 --> 00:36:12,770 You want Auntie Emily to make it better? 562 00:36:14,290 --> 00:36:18,488 All those years I stuck up for you with your father. 563 00:36:18,490 --> 00:36:21,408 You messed up. Again. 564 00:36:21,410 --> 00:36:23,170 For once in your life, own it. 565 00:36:25,450 --> 00:36:27,048 I don't get it. 566 00:36:27,050 --> 00:36:28,568 You and Rahul. 567 00:36:28,570 --> 00:36:30,768 You go to all these lengths to protect his reputation, 568 00:36:30,770 --> 00:36:33,528 yet you show no interest in who might have killed him. 569 00:36:33,530 --> 00:36:35,890 You don't even seem to even care that he's dead! 570 00:36:37,290 --> 00:36:39,850 Maybe I've learnt to bury my emotions. 571 00:36:41,690 --> 00:36:42,890 You should try it. 572 00:36:44,810 --> 00:36:46,888 You know they're onto you, 573 00:36:46,890 --> 00:36:49,608 and I'm not going to help you this time. 574 00:36:49,610 --> 00:36:50,890 Oh, please. 575 00:36:52,490 --> 00:36:53,930 This is so painful. 576 00:37:00,690 --> 00:37:03,128 So, all roads lead to Braithwaite. 577 00:37:03,130 --> 00:37:05,448 Yes, but it's all circumstantial. 578 00:37:05,450 --> 00:37:08,128 There's nothing directly connecting her to Wilfred. 579 00:37:08,130 --> 00:37:10,488 If you can find me something concrete, I'll bring her in, 580 00:37:10,490 --> 00:37:12,408 but until then, it's just speculation. 581 00:37:12,410 --> 00:37:14,808 Adam, where did you get to? 582 00:37:14,810 --> 00:37:17,368 Rahul's conduct during Fletcher's operation amounted to 583 00:37:17,370 --> 00:37:19,328 criminal negligence. 584 00:37:19,330 --> 00:37:21,408 He could have been charged for manslaughter. 585 00:37:21,410 --> 00:37:22,768 Well, he's dead. 586 00:37:22,770 --> 00:37:24,728 What if Braithwaite covered it up? 587 00:37:24,730 --> 00:37:27,128 That's attempting to pervert the course of justice. 588 00:37:27,130 --> 00:37:28,648 Which means you can arrest her. 589 00:37:28,650 --> 00:37:31,728 Oh, and how do we know that Braithwaite swaps the ECG? 590 00:37:31,730 --> 00:37:34,128 We can't. There are several sets of prints on the trace, 591 00:37:34,130 --> 00:37:35,728 one of which could be Braithwaite's. 592 00:37:35,730 --> 00:37:38,168 Exactly, so we can't just arrest her on the off-chance that 593 00:37:38,170 --> 00:37:39,608 her prints are on there. I know. 594 00:37:39,610 --> 00:37:41,090 ADAM: I met her for a drink. 595 00:37:45,050 --> 00:37:46,808 Her prints are on this glass. 596 00:37:46,810 --> 00:37:50,048 When you find that they are the same as the sets on the ECG, 597 00:37:50,050 --> 00:37:52,808 then you can arrest her. That's not admissible as evidence! 598 00:37:52,810 --> 00:37:54,450 It doesn't have to be. 599 00:37:55,970 --> 00:37:59,368 How do we know for sure she touched this glass? 600 00:37:59,370 --> 00:38:01,570 Well, you're just going to have to trust me. 601 00:38:48,210 --> 00:38:49,690 You two go round the back. 602 00:38:53,650 --> 00:38:55,130 DOORBELL RINGS 603 00:39:01,330 --> 00:39:03,410 Her car's here. Looks like she's home. 604 00:39:06,490 --> 00:39:07,530 No letterbox. 605 00:39:12,010 --> 00:39:13,370 Dr Braithwaite? 606 00:39:14,370 --> 00:39:16,730 DS Galloway. Could you open the door, please? 607 00:39:21,090 --> 00:39:23,210 Police! Dr Braithwaite? 608 00:39:35,330 --> 00:39:36,410 Shit. 609 00:39:42,690 --> 00:39:44,330 No sign of external injury. 610 00:39:46,170 --> 00:39:49,568 Both front and back doors were locked from the inside. 611 00:39:49,570 --> 00:39:52,168 There's no signs of forced entry. 612 00:39:52,170 --> 00:39:53,690 Everything's neat and tidy. 613 00:39:55,850 --> 00:39:57,210 Sudden chest pain, maybe? 614 00:39:58,730 --> 00:39:59,770 Or suicide. 615 00:40:32,210 --> 00:40:35,090 Nikki. Adam. Look at these. 616 00:40:40,610 --> 00:40:43,810 Two samples with Wilfred Okoye's name on. 617 00:41:06,810 --> 00:41:08,768 Look at this. 618 00:41:08,770 --> 00:41:11,048 The boiler's locked out. 619 00:41:11,050 --> 00:41:12,968 Yeah. Mine does that all the time. 620 00:41:12,970 --> 00:41:14,210 Bloody things. 621 00:41:52,610 --> 00:41:55,170 Heart weighs 380g. 622 00:42:21,330 --> 00:42:24,170 Evidence of left ventricular hypertrophy. 623 00:42:25,530 --> 00:42:27,010 Valves unremarkable. 624 00:42:30,330 --> 00:42:34,168 Left anterior descending coronary artery. 625 00:42:34,170 --> 00:42:37,210 Moderate stenosis, no evidence of thrombus. 626 00:42:45,610 --> 00:42:48,248 The toxicology was entirely negative, 627 00:42:48,250 --> 00:42:50,808 apart from a modest level of alcohol. 628 00:42:50,810 --> 00:42:54,768 No paracetamol, no benzodiazepines, nothing. 629 00:42:54,770 --> 00:42:58,368 So this, together with the absence of pills and containers 630 00:42:58,370 --> 00:43:01,328 at the address, and the absence of any needle marks on the body, 631 00:43:01,330 --> 00:43:04,488 leads me to conclude that death was not as a result 632 00:43:04,490 --> 00:43:07,048 of suicide or poisoning. 633 00:43:07,050 --> 00:43:10,528 In fact, the only significant finding from the postmortem 634 00:43:10,530 --> 00:43:13,488 examination is moderate ischaemic heart disease, 635 00:43:13,490 --> 00:43:16,928 together with hypertrophy of the septum and left ventricular wall. 636 00:43:16,930 --> 00:43:19,888 But no evidence of coronary thrombosis? 637 00:43:19,890 --> 00:43:22,848 The ventricular wall thickness... Heart attack. ..and the degree 638 00:43:22,850 --> 00:43:26,648 of myocardial disarray on microscopy are borderline 639 00:43:26,650 --> 00:43:28,688 for a diagnosis of HCM. 640 00:43:28,690 --> 00:43:31,608 What's that? Hypertrophic cardiomyopathy. 641 00:43:31,610 --> 00:43:34,968 It's an inherited heart condition that can lead to sudden death. 642 00:43:34,970 --> 00:43:36,850 Fabrice Muamba. Yes. 643 00:43:38,770 --> 00:43:42,488 Bolton Wanderers versus Tottenham. FA Cup quarterfinal, 2012. 644 00:43:42,490 --> 00:43:44,448 He collapsed on the pitch. Nearly died. 645 00:43:44,450 --> 00:43:46,328 Well, technically he did. 646 00:43:46,330 --> 00:43:48,368 In cases of high stress or exercise, 647 00:43:48,370 --> 00:43:52,488 the heart can lead into an abnormal rhythm, which can be fatal. 648 00:43:52,490 --> 00:43:55,408 And Emily Braithwaite was under a lot of stress. 649 00:43:55,410 --> 00:43:59,888 So it is possible that this caused a dysrhythmic event... 650 00:43:59,890 --> 00:44:02,690 Heart attack. ..that led to her death, don't you think? 651 00:44:06,690 --> 00:44:08,688 How come she didn't have a letterbox? 652 00:44:08,690 --> 00:44:11,048 It's a passive house. It's so well-insulated, 653 00:44:11,050 --> 00:44:13,728 it doesn't need heating. You heat it up just by living in it. 654 00:44:13,730 --> 00:44:15,488 But it has to be really airtight. 655 00:44:15,490 --> 00:44:17,608 It's like living in a bubble. 656 00:44:17,610 --> 00:44:20,810 All the air goes in and out through a single ventilation system. 657 00:44:22,450 --> 00:44:25,368 But why would the boiler lock out? 658 00:44:25,370 --> 00:44:29,808 What if it was faulty and produced a lot of carbon monoxide? 659 00:44:29,810 --> 00:44:32,170 No carbon monoxide in the toxicology. 660 00:44:36,450 --> 00:44:39,048 She's a suspect in a murder case. She conveniently dies. 661 00:44:39,050 --> 00:44:40,888 What if others were involved? 662 00:44:40,890 --> 00:44:43,008 If you can tell me how they did it, I'll believe you, 663 00:44:43,010 --> 00:44:46,528 but until then, it's looking like natural causes. 664 00:44:46,530 --> 00:44:50,088 Right, then, provisional assumption is that Braithwaite 665 00:44:50,090 --> 00:44:52,808 was guilty of conspiracy to murder Wilfred Okoye, 666 00:44:52,810 --> 00:44:55,768 as well as perverting the course of justice in the Fletcher case. 667 00:44:55,770 --> 00:44:56,968 What about Simi? 668 00:44:56,970 --> 00:45:01,008 That's up to the CPS, whether they buy a self-defence plea. 669 00:45:01,010 --> 00:45:02,530 I'll keep you posted. 670 00:45:20,530 --> 00:45:22,810 So this is where you've been hiding. 671 00:45:25,010 --> 00:45:26,808 Adam told you, then? 672 00:45:26,810 --> 00:45:29,330 Oh, yeah. He told me everything. 673 00:46:25,730 --> 00:46:27,128 I don't get it. 674 00:46:27,130 --> 00:46:30,128 How could someone like Braithwaite justify it to herself, 675 00:46:30,130 --> 00:46:31,448 let alone anyone else? 676 00:46:31,450 --> 00:46:33,968 They get fixated on the prize, don't they? 677 00:46:33,970 --> 00:46:37,530 The breakthrough, and all the acclaim that goes with it. Mm. 678 00:46:38,650 --> 00:46:41,850 Did you ever want to do something like that? Fancy research job? 679 00:46:42,850 --> 00:46:44,690 I think you'd be really good at that. 680 00:46:47,610 --> 00:46:48,650 I don't know. 681 00:46:49,770 --> 00:46:51,650 It's more Adam's world. Mm. 682 00:46:52,810 --> 00:46:54,010 Not any more. 683 00:46:55,690 --> 00:46:58,448 You can see how liberated he's been. 684 00:46:58,450 --> 00:47:01,528 He's carried that secret around for so long. 685 00:47:01,530 --> 00:47:05,088 Well, he's stopped trying to be all things to all men. 686 00:47:05,090 --> 00:47:08,010 And I'll tell you, he loves beating himself up. 687 00:48:07,450 --> 00:48:10,968 Hi. I'm working on the case of Wilfred Okoye. 688 00:48:10,970 --> 00:48:13,248 I was wondering if I could get his microbiology results 689 00:48:13,250 --> 00:48:14,688 from his stay here. 690 00:48:14,690 --> 00:48:17,170 Date of birth is 9/7/66. 691 00:48:22,490 --> 00:48:25,088 I just need to, er, speak to my supervisor. 692 00:48:25,090 --> 00:48:26,330 OK. Thank you. 693 00:49:04,210 --> 00:49:06,008 PHONE PINGS 694 00:49:06,010 --> 00:49:07,570 It's Adam. 695 00:49:09,770 --> 00:49:11,370 "We were wrong about everything. 696 00:49:13,450 --> 00:49:16,090 "At Cowley Institute. Come quickly." What? 697 00:49:19,490 --> 00:49:21,368 What are we looking at? 698 00:49:21,370 --> 00:49:24,210 Wilfred's blood cultures. Microbiology report. 699 00:49:27,050 --> 00:49:28,290 Hang on. 700 00:49:29,610 --> 00:49:33,328 The antibiotic sensitivities have been reversed. 701 00:49:33,330 --> 00:49:34,808 Who's done that? Braithwaite? 702 00:49:34,810 --> 00:49:37,370 Couldn't be. These are from the Cowley institute. 703 00:49:40,010 --> 00:49:41,610 Adam needs us. Come on. 704 00:50:11,250 --> 00:50:12,648 SHE SIGHS 705 00:50:12,650 --> 00:50:15,490 Oh, great. We were supposed to go left back at the lights. 706 00:50:29,770 --> 00:50:31,210 CAR DOOR OPENS 707 00:50:32,850 --> 00:50:33,968 Dr Yuen? 708 00:50:33,970 --> 00:50:37,168 You know Emily Braithwaite died yesterday? 709 00:50:37,170 --> 00:50:41,408 What? Uh, no. How did it happen? 710 00:50:41,410 --> 00:50:44,570 Unknown. Found dead in a house that was bolted from the inside. 711 00:50:46,090 --> 00:50:48,650 Oh, look, an oxygen analyser. 712 00:50:50,050 --> 00:50:51,928 Do you always keep one of those in your car? 713 00:50:51,930 --> 00:50:53,768 I use it for various things. 714 00:50:53,770 --> 00:50:57,048 So Emily died just as you convinced us she was guilty. 715 00:50:57,050 --> 00:50:59,768 Her work was based on exploitation. 716 00:50:59,770 --> 00:51:01,968 Well, she can't deny that now, can she? 717 00:51:01,970 --> 00:51:03,328 Well, whatever happened, 718 00:51:03,330 --> 00:51:06,608 I'm sure forensic science will find the answer. 719 00:51:06,610 --> 00:51:10,088 Mm. Then I realised just how much liquid nitrogen you go through here. 720 00:51:10,090 --> 00:51:12,090 Two deliveries in three days? 721 00:51:14,250 --> 00:51:17,648 I mean, that is some evil genius stuff. 722 00:51:17,650 --> 00:51:19,808 Pretty quick and very clean. 723 00:51:19,810 --> 00:51:23,408 Except the pilot light in the boiler went out at Braithwaite's house. 724 00:51:23,410 --> 00:51:24,810 Otherwise, the perfect crime. 725 00:51:26,050 --> 00:51:27,448 Are you insane? 726 00:51:27,450 --> 00:51:30,490 Oh, sorry. That's forensic science. Get out. 727 00:51:34,770 --> 00:51:37,450 Braithwaite had Wilfred's blood samples. She was onto you. 728 00:51:38,730 --> 00:51:40,528 My research is changing lives. 729 00:51:40,530 --> 00:51:42,248 She never made the crucial breakthrough, 730 00:51:42,250 --> 00:51:43,808 but then again, neither did you. 731 00:51:43,810 --> 00:51:45,968 You reckon you'll crack it any minute now, don't you? 732 00:51:45,970 --> 00:51:48,448 You just have to keep going, keep blasting innocent men 733 00:51:48,450 --> 00:51:50,928 and women with poisonous drugs, and then you'll get there. 734 00:51:50,930 --> 00:51:53,688 You know nothing. There's no gene editing going on here. 735 00:51:53,690 --> 00:51:56,128 Your magic treatments are all from stem cells that you get 736 00:51:56,130 --> 00:51:57,608 from killing people like Wilfred. 737 00:51:57,610 --> 00:52:01,288 When childhood cancer is a thing of the past thanks to me, 738 00:52:01,290 --> 00:52:03,568 no-one will care. 739 00:52:03,570 --> 00:52:06,128 That's what it's all about, isn't it? 740 00:52:06,130 --> 00:52:10,610 It's not about the money or the power. It's about the prestige. 741 00:52:12,250 --> 00:52:14,848 So what are you going to do about it, Adam? 742 00:52:14,850 --> 00:52:16,848 Mm? You're discredited. 743 00:52:16,850 --> 00:52:18,290 You're getting struck off. 744 00:52:19,530 --> 00:52:22,168 Of course I know! 745 00:52:22,170 --> 00:52:23,330 I know everything. 746 00:52:25,890 --> 00:52:28,290 You've no idea who you're dealing with. 747 00:52:30,730 --> 00:52:31,970 Adam? 748 00:52:34,210 --> 00:52:35,250 Adam! 749 00:52:37,610 --> 00:52:41,168 PHONE RINGS 750 00:52:41,170 --> 00:52:43,688 Adam? What's happening? 751 00:52:43,690 --> 00:52:47,088 Cowley's the one exploiting Wilfred and the rest of the donors. 752 00:52:47,090 --> 00:52:49,288 And he killed Braithwaite with liquid nitrogen. 753 00:52:49,290 --> 00:52:51,408 He poured it in the vent of her airtight house, 754 00:52:51,410 --> 00:52:54,888 turning it into a gas chamber. She suffocated. 755 00:52:54,890 --> 00:52:57,888 Cowley did a deal with Rahul to kill Wilfred during surgery. 756 00:52:57,890 --> 00:53:00,810 And when that failed, he attacked Wilfred with the bacteria... 757 00:53:03,130 --> 00:53:05,368 ..to make sure he switched the micro reports 758 00:53:05,370 --> 00:53:07,368 so that the antibiotics wouldn't work. 759 00:53:07,370 --> 00:53:09,250 ENGINE REVS 760 00:53:20,690 --> 00:53:21,890 Adam? 761 00:53:23,130 --> 00:53:24,450 Adam! 762 00:53:34,050 --> 00:53:35,490 HE COUGHS 763 00:53:43,970 --> 00:53:47,768 I'm sure that's Cowley. Really? Call Cracknell. 764 00:53:47,770 --> 00:53:49,970 But... Get after him. I'll find Adam. 765 00:53:58,570 --> 00:54:02,568 Yeah, I'm heading north on Colbridge Road. 766 00:54:02,570 --> 00:54:05,328 It's a black Mercedes. 767 00:54:05,330 --> 00:54:06,688 Adam? 768 00:54:06,690 --> 00:54:07,808 Adam! 769 00:54:07,810 --> 00:54:09,170 Oh, Jesus. 770 00:54:12,530 --> 00:54:14,048 Ambulance. 771 00:54:14,050 --> 00:54:17,290 SIRENS WAIL 772 00:54:20,170 --> 00:54:22,408 Can you hear me? Adam? 773 00:54:22,410 --> 00:54:24,928 You took your time, mate. 774 00:54:24,930 --> 00:54:26,330 Come to take all the credit? 775 00:54:28,170 --> 00:54:29,450 Oh, man. 776 00:54:30,930 --> 00:54:33,648 The ambulance is on its way. What happened? 777 00:54:33,650 --> 00:54:34,890 I messed up. 778 00:54:51,010 --> 00:54:52,170 You trusted me. 779 00:54:55,930 --> 00:54:57,010 That means a lot. 780 00:54:59,050 --> 00:55:01,528 Adam. Adam, stay with me. 781 00:55:01,530 --> 00:55:03,848 Adam. Come on, man. Stay with me. Stay with me. 782 00:55:03,850 --> 00:55:05,130 Come on! Adam! 783 00:55:06,410 --> 00:55:07,450 Adam! 784 00:55:25,690 --> 00:55:29,490 SIREN WAILS 785 00:55:54,530 --> 00:55:55,570 Oh, God. 786 00:56:02,650 --> 00:56:04,050 Oh, no. 787 00:56:08,570 --> 00:56:12,290 SHE SOBS 788 00:56:36,170 --> 00:56:42,530 # Testator silens 789 00:56:45,370 --> 00:56:52,168 # Costestes e spiritu 790 00:56:52,170 --> 00:56:58,650 # Silencium. # 99873

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