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It's 39 degrees Celsius outside.
Do you realise how ridiculous I look right now?
Look, it made the other bacteria grow.
Mrs Abdul-Hai, I'll think of something.
We're performing a kidney transplant
on Felicitas Abdul-Hai today.
We could lose our jobs.
The inflammation has to come down.
What's your recommendation?
Stop the reform!
Stop the reform! Stop the reform!
Hey, hey, Lou! Wait a minute.
I don't have time.
No time for the good cause?
The good causes.
Come on, Lou. We need to set an example.
Piss in the government's soup when they trample on justice.
You're still full of shit.
Hey man, you used to be on the right side.
And that got me in deep shit.
I'm sick of your bullshit.
You'll come back!
Stop the reform! Stop the reform!
- Maral? - Dylan.
We've been going about this all wrong!
Have we?
The paleobacterium isn't the problem,
it's the body's immune response.
This leads to damage to the organs
and the microbiome.
But from where?
If we use the paleobacterium
correctly, in the gut,
- not in the blood... - Yes?
Then it controls the growth of the other bacteria.
The paleobacterium
isn't the poison, but the cure!
Mr Baldwin needs more of this bacterium.
Multi-resistant germs
cannot be integrated.
You have to fight them.
My finding proves the opposite.
No. There's a man out there fighting for his life
and you want to give his relatives hope
because it suits your research? That's hubris, Maral!
We'll start with the phages. They've been tried and tested
and weren't just made up overnight.
My approach is validated.
Look at this.
Multiplication in progress.
I made an AI simulation.
Here you can see: Eubiosis
is produced in a few hours.
AI cannot replace a study.
I've already got drugs through the FDA with AI simulations.
We're not in Boston.
I don't need your approval.
I will treat Mr Baldwin as I see fit.
Great collaboration.
Morning.
Good morning.
We'll have to completely rethink your husband's case.
Didn't Dr Van Boeken want to do the phage treatment?
Er, right, but I don't think that will work.
You see, for him
it's about fighting the bacterium.
Whereas my aim is
to integrate it into the microbiome in larger quantities
so that it can activate regeneration.
We're dealing with a completely new type of bacterium here.
Let me explain it to you.
So...
So, let's say this sphere here
is the bacterium,
the paleobacterium.
It was trapped in ice for thousands of years
but was released by global warming
and washed into the North Sea by deep currents.
And through this tiny little cut in your husband's finger,
this bacterium
entered his bloodstream while he was diving.
So, my pad is his bloodstream.
The bacterium enters his entire body through the blood
and triggers an overreaction of the immune system.
This disrupts the microbiome,
that is, these tokens here.
The bacterium now enters the microbiome through the bloodstream.
The unbalanced microbiome
fires up the inflammation,
causing the immune system to react even more.
The microbiome exacerbates the inflammation,
creating a momentum of its own that can no longer be stopped.
However, if we now...
introduce the bacteria
not through the blood, but directly
into the microbiome,
it suddenly no longer has a destructive effect
but...
a reconstructive one.
Sounds like hocus-pocus to me, sorry.
Have you ever done this before?
Your husband's the first.
As no conventional therapy works for him,
he is a hardship case.
And in a case of hardship,
we're allowed to try yet unauthorised treatments.
It's an individual treatment attempt.
You haven't tried all the treatments yet.
Based on my evaluations,
this approach is the only way to save your husband.
We want to try Dr van Boeken's suggestion.
You know the budget meeting is coming up?
I'll be there shortly.
What's wrong?
I want to try a treatment attempt with a patient,
but Dylan's trying to stop me.
He's even turning the relatives against me.
So what next?
Well, nothing. It's stressing me out.
That's stressing you out?
You really don't sound like a boss right now.
You know what, just forget it.
Listen, you've chosen a difficult profession.
It requires decisiveness,
a strong will and the courage to take risks.
Believe me, I know what I'm talking about.
Yeah.
You don't let anything derail you.
I always do what I think is right, yes.
- I know. - Yeah.
And if you're that intimidated by a colleague,
then maybe you're really not right for the position.
Third attempt complete. Run five.
No physical reactions measurable.
Wake up.
Hey Lars, the session's about to start.
I'll be with you in a minute.
OK, I'll get started.
Ferhat, where are you?
Lars Kirch.
Williamson Cyber Stimulation Therapy, fourth attempt.
Here.
Throw the ball as far as you can.
I'm a pro surfer, I'm not here to play around.
I want to get on a real board,
with real wind, real water,
the real smell of the sea!
It just smells like...
hospitals here.
I can see if I...
can programme another smell.
Now please throw the ball.
Hey, maybe we'll have a little success today.
Alright.
No response.
Well?
Here, have another shot.
No response.
No response.
- It's not working. - Not yet.
Come on, just keep going.
Marlene.
I was just at the budget meeting with Emilia Bonetti.
She's taking a pretty tough line.
Some programmes are even being cut.
All the more important we keep going!
How's Mrs Abdul-Hai doing?
Is the aftercare working?
Yes, she's walking and washing herself.
Ah, very good.
We've been very lucky.
We've done a great job.
Seda! We're understaffed and not well equipped.
Better to take a risk than do nothing.
We helped a patient, that's the only thing...
Not a solution! Do you want to operate
on everyone who falls through the cracks?
The problem lies elsewhere.
I know, but you still have to
do something...
Hello?
Hello, can you hear me?
Yes. I was just on my way to the cooling spaces.
I'll be fine.
- Let me take your bag. - It's OK.
Everything's OK.
- What's wrong with your leg? - Nothing...
It's nothing.
You're coming with us.
Delayed healing of a tibial fracture
with subsequent
development of pseudoarthrosis.
It isn't that bad.
No! No, it is bad.
You had a bone fracture in the tibia
that didn't merge stably.
A defective joint has formed, a so-called pseudoarthrosis,
hence the swelling and pain in your leg.
Your leg needs operating on.
Oh no. Please, no.
No operation, please.
But you can't go on like this.
Bolton, did you say?
B-O-L-T-O-N, Gillian?
I can't find you in the system.
I...
I have no insurance.
I came here two years ago from LA and I just have...
a tolerated stay permit.
Did you flee from the fires?
And your family?
We were separated.
My mum and my son
ended up in France.
I've been trying to get them...
to join me ever since.
Don't be afraid.
We'll take care of your leg.
We have to fight the immune reaction -
not the paleobacterium.
That's why the phages won't help.
We have to rethink.
The phages are the most effective
and reliable means we have
against multi-resistant bacteria.
And this paleobacterium is multi-resistant.
Why can't you see it's not about the pathogen?
Phage therapy will only cost us valuable time.
We must start the ITA immediately
to save Mr Baldwin.
The time pressure is precisely why
we can't keep experimenting with unreliable methods!
And you're sure it will work?
Of course I can't guarantee it 100%.
But I'm very sure
that the inflammatory reaction
cannot be stopped by
anything other than the bacterium itself.
The patient will die
if we don't try this new treatment.
Emilia.
Do the treatment attempt.
You can't be serious.
The Charité wouldn't be the Charité
if it didn't keep breaking new ground.
We promote progress here.
If such an opportunity arises with Maral's trial,
then we will get behind it.
That's one of the reasons we brought her here.
Thank you.
Let's hope that your obsession with progress
isn't to the detriment of patients.
Wait a minute.
I'm going out on a limb for you here.
The first sign that it's ineffective, you stop,
understand?
Yes.
Once you have the relatives' consent,
you can get started.
I need to talk to you again.
Due to your husband's high inflammation levels,
it's only a matter of time
before other internal organs fail.
Phage therapy won't be able to help here
because it's fighting a problem
that is simply no longer the cause.
The new treatment attempt is his only chance.
And what are the chances?
I can't say exactly.
But I'm convinced that it will save your husband's life.
But Dr Safadi,
please, don't get me wrong,
you're certainly an excellent doctor.
But you also make mistakes and even you can be wrong.
But if I am right,
not only will it save your husband,
but other infected people in the Netherlands.
We can't predict how many infected people there will be globally.
Ah, right.
So this isn't about Piet.
This is about your reputation!
And you want to turn him into a guinea pig!
- No, no. - Oh, Rupert, please!
Oh, I'm sorry.
- He's a bit haywire. - Yes, I am.
You won't get our approval!
- It's not just your decision. - Or yours.
I'm responsible for Piet.
Do you really want to risk his life?
We agreed on the phage therapy.
Please, please, please.
Maybe you'd like to discuss this...
outside in private.
Doctor?
Doctor Safadi?
Mr Baldwin.
Rup... and Evelyn...
Too difficult...
Decision...
The decision is too difficult for Evelyn and Rupert?
Yes.
Do the treatment attempt.
I... I don't want to die.
OK.
I need your consent in writing.
OK, yes.
Er, what is it?
Sit down.
How are you?
I heard about the success of your memory trauma therapy
with the little patient.
Congratulations.
Is that why I'm here?
No.
I have some news.
The research committee at Harvard
has changed their priorities for external funding.
They're pooling some of their funds
to further increase the budget for Planetary Health.
Does that affect my research?
Yes.
The commission has decided to phase out
your Locked-in project.
What?
Why?
The commission's reasoning is that
progress is insufficient and the costs are too high.
That's not true at all.
We're on the verge of a breakthrough.
I'm sorry, Ferhat.
I'm just the messenger. I can't do anything else.
Yes, the Charité has to make up the money.
That's impossible.
The heat damage and the reform are already costing enough.
My research will set new standards in many areas.
The participants can already move in the cyberverse
and we're so close to reading
their movement patterns from the brain,
transferring them to the muscles
and feeding the sensory signals back to the brain.
I'm sorry.
But your research question is simply
no longer considered so urgent at the moment.
What am I supposed to tell my patients?
"Sorry guys, Locked-in syndrome
just isn't that urgent now".
I can't see you at all right now, sorry!
I can understand your fears about your husband.
- But I'm sure... - It's just...
no matter how sure you are, there's no guarantee
that this will work, OK?
I'm trying to convince him. I'm really trying!
Great, now you're teaming up.
You're not getting a yes from me.
To be honest, that won't be necessary anymore.
When I was with your husband earlier,
he spoke to me.
He asked me to start the treatment attempt.
Anyone can say that.
I have his consent in writing.
How did you get into the programme?
Layla let me in.
Can you stop a minute? I need to talk to you.
What's up?
We have to pause our project.
For how long?
Until we've found a new funder.
But that could take forever, right?
Fuck!
Do I have to go back to the home?
Listen, I'll do anything...
I'm not going back to that dump!
Wait, wait... throw it again!
Your... your hand moved.
Throw!
Movement detected.
I'm throwing!
Come on, keep going!
I'm throwing!
OK, let's take a break.
This... this is crazy!
Your anger must've been the key to the impulse.
We can't cancel the programme now!
Yes, you're right.
What's going on?
You wanted a research success?
Allow me to introduce my patient Lars Kirch.
He moved his hand today for the first time in five years.
I have all his data.
Here.
The Charité must continue to fund the project.
There.
The spikes are Lars' movement patterns.
Yes.
Please excuse us for a moment.
Come with me.
I'm really pleased that
you've made such progress in such a short time,
but I also know how fragile such successes are.
Even if I do stand up for you,
we're not talking about an extension of a few weeks.
Mr Kirch isn't going to get up and go home next month -
if he ever manages to do that again!
It will take years and you know that.
Internal research funds have to be released for the long term.
For a niche project with slow results.
I'm sorry, that's just not realistic.
Fever 39.9, tachycardia 130 BPM,
hypotensive 60/40 mmHg,
peripheral saturation 85%.
It's time. Good.
We're going to start now, OK?
Start with the microbiome therapy
by injection into the gut.
We'll know more in about two hours.
Good. Thank you.
CHARITÉ - SHADOW CLINIC
You should become a surgeon after all.
But it still can't go on like this.
I hope you realise that.
Yes...
Did you switch off your locator?
Oh.
- Seda! - Yeah, yeah.
Locator off.
What are you still doing here?
My Locked-in project is being cancelled.
What?
Despite having made a huge breakthrough.
Harvard has cut its third-party funding.
So what now?
Now...
I'll send everyone home and then...
I'm left with nothing.
Oh, come on.
There must be something else in your life.
This project is my life.
Hey, why don't you go out!
Go eat, go dancing, go drinking.
Experience something beyond just the Charité.
With whom?
With me?
Yeah, well not everything at the same time.
- OK. - Food...
Clean Meat?
- Wednesday evening? - OK.
OK.
Message from Maral.
Hey, I can't make it today,
I'll be back later.
Call my sister.
Hey Julia, what's up?
Hey.
I just wanted to say hi again.
Ah, I'm just taking Zac to sports.
Can I call you back later?
What did you say, Zaggy? Yes, I know it's really hot.
But we have to go now.
Sorry Juli, let's talk later, yeah?
OK, sure, no problem.
Everything OK with you?
Yes, everything's great.
And with Maral?
Also fine.
She's... um... is on the trail
of another medical discovery.
So all's well, then. I'll call you later, OK?
- Alright. Bye. - Bye.
Shit.
Oh God.
- Do something! - We're taking care of it.
Your hazmat suit?
No time for that. Come on, help me!
I've got it. I've got it.
The dose was too low.
We need to give him more.
Maral, that's enough now.
Breakthrough at the Charité.
The doctors were able to prove
that the so-called paleobacterium
cannot be transmitted directly from person to person.
The mysterious pathogen remains highly dangerous.
New cases are occurring almost daily,
especially in northern Europe.
Many of them are in mortal danger.
Public pressure on the scientific community is growing.
Also in Berlin, where a small group of doctors
have declared war
on the deadly bacterium.
His inflammation levels have fallen slightly.
And as the bacterium obviously doesn't spread
from person to person,
he doesn't have to remain in the isolation ward.
- That's already a start. - He's in a coma!
You act like that's a good thing.
An induced coma is not a bad thing per se.
It takes the pressure off
so that his body
can fully focus on healing.
I can understand your concerns.
But I assure you,
we'll do the right thing for your husband.
Excuse me.
Yes?
You look exhausted.
Is that why you wanted to talk to me?
- You can't go on like this. - Of course I can.
If you increase his dose again, he'll die.
I admit that the dose increase isn't
as straightforward as I thought.
- Yes. - But I'm getting there.
It's irresponsible -
medically and ethically. I'm going to see Emilia.
- Wait! - What?
If Mr Baldwin's condition doesn't change
by tomorrow morning,
then you can take over.
Twelve hours.
Looks good so far.
But you mustn't put any weight
on it for the next four weeks.
OK.
I'll give you some crutches.
- Thank you. - Hello.
We're looking for Gillian Bolton.
Er, I can't give you any information there.
Yes, you can. In fact, you're legally obliged to.
Are you Gillian Bolton?
You were registered in the system yesterday.
- What do you want from her? - To take me.
I'm being...
deported.
I thought you had tolerated status?
Not for a long time.
But why did you...
Then come with me, Miss Bolton.
Stop! She can't walk!
What's going on?
Theo Wallin, Return Management of the Immigration Office.
This is my ward.
You can't just come here and cart my patient out.
If your patient is in the country illegally,
we can do that. Please step aside.
But she needs proper aftercare.
Her leg will get infected.
Someone else will take care of it.
You can't do this.
This is insane! It's negligent.
You're responsible.
It's OK, really.
It's OK.
Just a minute.
Come here. Slowly.
Any belongings?
My bag.
Thank you so much for everything.
Just wait a minute!
I hope you can be with your family again soon.
Everything will be fine.
Goodbye.
Everything will be fine.
Goodbye.
- Hey Owen. - Hey Seda.
Paris Marathon again this year?
Every year.
Hey, erm...
- I have a hypothetical question. - Hmm?
If a fellow runner were to get injured who,
let's say,
didn't have health insurance,
would you treat the woman off the record?
It depends... on the injuries.
I'm not a surgeon.
I'm an anaesthetist.
Yes, of course,
but that doesn't matter now.
The question is purely ethical.
You mean,
would I help people...
who've... who've fallen through the cracks?
Well, of course.
Good.
Hey, can I ask you something?
How many times have you had
an operation cancelled because the scoring was too bad?
Twice, I would say.
How do you deal with that?
Well, I don't operate.
- Right. - Right.
Hey, I need you...
urgently.
I was having an important discussion.
I know everything.
You do?
You were trying to get Ivana
to conspire with you.
What are you talking about?
Listen, I know about these things.
Remember the fracking decision?
Yes.
I was part of the Chancellery hacking back then.
One of the demonstrators in front of the hospital
was also part of it.
But they all ended up in prison.
Yes, exactly.
We served two years -
for membership of a terrorist organisation.
But we don't need a terrorist here.
We treat people, not plan attacks.
But you're planning something else,
to do with the reform, right?
Why are you telling me this?
Because I want to join you.
I'm struggling with these new developments as much as you.
Really.
Let's say there was some kind of...
conspiratorial action...
Could you hack into the hospital system and get us
intel on unused blood reserves
and infusions and stuff?
Of course. I could've even told you that
Gillian Bolton is on the deportation list.
Good.
Then welcome to the shadow clinic.
OK.
CHARITÉ VILLAGE - BRANDENBURG
You have a beautiful home.
Sometimes I wonder if it really is...
my home.
Do you miss the States?
My sister.
Friends.
Oh, it's probably just the new environment.
The environment...
aha.
I feel like... I've somehow lost touch...
with Maral since...
we've been here.
We used to hang out way more in Boston.
And now this whole thing with Michel...
We have to accept it when our children grow up
and go their own ways.
That's exactly what Maral says.
But I think she just wants to do it differently to Seda.
You could be right.
The tension between those two is unbearable.
Maybe they're just too similar.
Don't let your daughter hear that.
Seda hasn't had it easy in life.
She was very young
when she had to flee Armenia, all alone.
How did you two meet, actually?
At the Love Parade.
Yes, it was love at first sight.
I then took care of Maral to cover Seda's back.
She's always...
demanded a lot from herself and others.
I didn't know any of that.
And you...
you are the best thing that could've happened to our family.
And you'll make new friends here in no time.
Just promise me you'll look after yourself.
Hey, you two!
- Hello. - So nice out here.
Ah, what a day!
Have a sip of that.
Listen, so...
- I'll get some more. - Thanks.
Did you know that
Nils and Seda
met at the Love Parade?
I've had quite a day,
I don't want to talk about my mum.
OK...
Did you talk to Michel?
Julia, I know how important the matter is to you,
and I promise I'll talk to him,
- OK? - OK.
- And when? - Oh Julia,
it's all a bit much right now.
I make this... this fascinating discovery,
and everyone, literally everyone,
is in my way.
And I don't understand why.
I'm off to bed.
What's up now?
Maral, you're so exhausting right now.
But I'm sure you'll show everyone in the end. Good night.
Whew, OK, erm...
As you know, today is the last time:
the last time looking at the sea.
The last time with sand under our feet.
The last time with water that isn't wet.
I'm...
so sorry that we can't continue together,
because I've grown very fond of you.
I will do everything...
everything I can to acquire new funding.
But it could take a while.
And until then...
I'm afraid I'll have to let you go.
OK.
Are you ready?
Yes?
Yes.
So, time's up.
His values are getting worse by the hour.
I'm going to start the phages.
No, you won't.
Yes I will. We have a deal.
I'm in charge of Microbiology.
And I make the decisions here.
We'll see about that.
NEUROTECHNOLOGY
Where are you taking me?
I've got a surprise for you.
What is this?
You don't have to go to the home.
I've made a deal with the management.
And you needn't worry about the costs.
What's the point?
I... I thought you'd be happy.
Happy? Are you serious, Ferhat?
And what exactly am I meant to be happy about?
That I can now raise my shitty hand
after all this time,
then find out that's probably all I'll ever be able to do?
Or about the fact that you lied to me
to keep me as your little research monkey?
Oh no, of course I should be most happy
that you're now salving your conscience with this room.
But you know what? I don't give a shit.
OK.
I didn't know that's how you felt.
I didn't lie to you about potential successes.
But I obviously should have clarified things more
to keep your expectations realistic.
I'm sorry about that.
I'll... leave you to it.
We'll talk later.
Maral? I need to talk to you.
Now? I'm in the middle of a treatment.
That's what I want to talk about.
Your treatment attempt is getting out of hand.
Did he tell you that?
He can't judge that at all.
Yes, he can.
I'm observing Mr Baldwin's condition just as you are.
Maybe you're no longer objective because you're in so deep.
Rubbish,
I know exactly what I'm doing.
Now let me get back to work.
I really appreciate your thirst for research, Maral.
But it's getting dangerous for the patient.
The treatment will stop now.
No, it won't.
And if that's a problem, we can take it
to the Ministry of Health.
I don't think you'll get any support from Nguyen right now.
I need to return to my patient.
He's not your patient anymore.
You're suspended.
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