Would you like to inspect the original subtitles? These are the user uploaded subtitles that are being translated:
1
00:00:02,579 --> 00:00:05,779
This programme contains some scenes
which some viewers may
find upsetting
2
00:00:05,819 --> 00:00:08,259
Victim is Mr Arnie Rahul.
Consultant surgeon. 48 years of age.
3
00:00:08,299 --> 00:00:11,059
Good reputation, though he's fallen
out with a few people recently.
4
00:00:11,099 --> 00:00:13,259
{\an8}He was about to start an operation.
He gets a phone call.
5
00:00:13,299 --> 00:00:14,499
Walks out, never comes back.
6
00:00:14,539 --> 00:00:16,939
Single puncture wound to
the left chest wall.
7
00:00:18,299 --> 00:00:21,019
What's that in his hand?
Looks like a syringe and needle.
8
00:00:21,059 --> 00:00:24,259
It's a Hickman line.
A long-term vascular access device
9
00:00:24,299 --> 00:00:26,779
for people who need chemotherapy
or blood transfusions.
10
00:00:26,819 --> 00:00:29,539
The assailant would have had
extensive cross contamination
11
00:00:29,579 --> 00:00:30,939
with the victim's blood.
12
00:00:30,979 --> 00:00:33,179
Stick that in to a big artery
and blood will flow out
13
00:00:33,219 --> 00:00:34,659
like a high-pressure hose.
14
00:00:34,699 --> 00:00:36,019
Simi Jacobs.
15
00:00:37,139 --> 00:00:38,499
He's denying everything.
16
00:00:39,539 --> 00:00:42,739
Simi Jacobs is not a match
17
00:00:42,779 --> 00:00:44,419
to the blood spatter at the scene.
18
00:00:44,459 --> 00:00:46,739
So, who is it? It's Wilfred Okoye.
19
00:00:46,779 --> 00:00:47,819
The patient?
20
00:00:47,859 --> 00:00:51,539
Arnie Rahul was murdered by a man
who was under general anaesthetic
21
00:00:51,579 --> 00:00:53,059
in a different room?
22
00:00:53,099 --> 00:00:56,579
Blood alcohol level, three times
the legal driving limit.
23
00:00:56,619 --> 00:00:59,019
You said he shouldn't be operating.
24
00:00:59,059 --> 00:01:01,019
Not after the Harry Fletcher
incident.
25
00:01:01,059 --> 00:01:03,899
Arrested on the table
during surgery last week.
26
00:01:03,939 --> 00:01:06,499
I want you to do the postmortem.
27
00:01:06,539 --> 00:01:08,739
Technically that would be
a conflict of interest.
28
00:01:08,779 --> 00:01:12,059
Summarising postmortem examination,
Harry Fletcher.
29
00:01:12,099 --> 00:01:13,979
What are you doing?
My colleagues are here.
30
00:01:14,019 --> 00:01:16,859
Is that Emily Braithwaite?
She's Adam's godmother.
31
00:01:16,899 --> 00:01:19,059
You'd think he might have
mentioned it.
32
00:01:19,099 --> 00:01:21,539
Are you going to confront him?
Not yet.
33
00:01:21,579 --> 00:01:23,979
Your original stem cell work
was brilliant.
34
00:01:24,019 --> 00:01:27,819
But you tried and failed to turn
it into a viable cancer treatment.
35
00:01:27,859 --> 00:01:30,419
Wilfred Okoye, still in
the hospital.
36
00:01:30,459 --> 00:01:32,099
What's he going to know?
37
00:01:32,139 --> 00:01:35,139
You won't find out unless you
ask him.
38
00:01:35,179 --> 00:01:37,979
Mr Fletcher died because of
surgical error.
39
00:01:38,019 --> 00:01:41,459
Adam! You have no idea what
you've done.
40
00:01:41,499 --> 00:01:44,019
When I applied for this job
I falsified my CV,
41
00:01:44,059 --> 00:01:45,899
and Emily Braithwaite tried to
use this
42
00:01:45,939 --> 00:01:48,139
fact to influence my findings in
the Fletcher Case.
43
00:01:48,179 --> 00:01:49,739
Here's my letter of resignation.
44
00:01:49,779 --> 00:01:51,099
Effective immediately.
45
00:01:52,619 --> 00:01:58,699
{\an8}# Testator silens
46
00:02:01,179 --> 00:02:08,339
# Costestes e spiritu
47
00:02:08,379 --> 00:02:15,779
# Silencium
48
00:02:23,139 --> 00:02:28,979
# Testator silens. #
49
00:02:35,099 --> 00:02:37,699
DISTANT SIREN
50
00:02:40,539 --> 00:02:44,019
Wilfred Okoye, a Beninese
farm worker, was admitted
51
00:02:44,059 --> 00:02:48,299
to St Jude's hospital for the
treatment of leukaemia a week ago.
52
00:02:48,339 --> 00:02:51,579
Although he lost consciousness
briefly during the attack
53
00:02:51,619 --> 00:02:55,339
on his life last night, he seems to
have recovered with no ill effects.
54
00:02:55,379 --> 00:02:59,619
Awaiting toxicology from the syringe
we believe was used in the attack.
55
00:02:59,659 --> 00:03:01,419
Prints? Fibres?
56
00:03:01,459 --> 00:03:03,699
Nothing conclusive.
We're interviewing witnesses
57
00:03:03,739 --> 00:03:05,859
but no-one got a good look at
the attacker.
58
00:03:05,899 --> 00:03:08,379
How come he's being treated here
in the UK?
59
00:03:08,419 --> 00:03:12,139
It was set up by a charity,
and then arranged through Rahul.
60
00:03:13,859 --> 00:03:18,099
Here is a man who has lived his
entire life in Benin
61
00:03:18,139 --> 00:03:22,219
up until a week ago, and,
according to our DNA evidence,
62
00:03:22,259 --> 00:03:26,459
murders his surgeon while under
anaesthetic in a different room.
63
00:03:30,179 --> 00:03:35,699
Could the DNA at the murder scene
been a contaminant or planted?
64
00:03:35,739 --> 00:03:38,419
No. The spatter patterns are
too perfect.
65
00:03:38,459 --> 00:03:40,779
It came from someone who
was in the room at the time.
66
00:03:40,819 --> 00:03:42,499
So, how do you explain it?
67
00:03:45,819 --> 00:03:48,819
How do we know Wilfred
was anaesthetised?
68
00:03:48,859 --> 00:03:51,619
I mean, how do we know it was him?
69
00:03:51,659 --> 00:03:53,299
What, he's got an identical twin?
70
00:03:53,339 --> 00:03:54,779
Bit fantastical, Steve.
71
00:03:54,819 --> 00:03:56,499
I don't know.
72
00:03:56,539 --> 00:03:58,139
There's another explanation.
73
00:04:00,259 --> 00:04:02,419
DNA samples got mixed up.
74
00:04:02,459 --> 00:04:04,459
Ah! No way!
75
00:04:04,499 --> 00:04:07,579
Look, I'm just putting it out there.
Mm-mn. We could run the test again.
76
00:04:07,619 --> 00:04:09,499
Those samples were
handled correctly.
77
00:04:11,059 --> 00:04:13,179
Jack, shall we just run them again?
78
00:04:16,499 --> 00:04:18,259
Right, yep. Good.
79
00:04:19,539 --> 00:04:20,539
OK.
80
00:04:21,739 --> 00:04:23,739
Let me know when toxicology
comes back.
81
00:04:32,059 --> 00:04:35,539
So, the samples got mixed up,
did they? It's always possible.
82
00:04:35,579 --> 00:04:36,539
Mm-hm.
83
00:04:37,619 --> 00:04:40,779
You know who took the swab from
Simi Jacobs. Adam.
84
00:04:42,259 --> 00:04:43,539
What are you suggesting?
85
00:04:45,539 --> 00:04:46,979
Just saying.
86
00:04:53,499 --> 00:04:55,819
PHONE RINGS
87
00:04:55,859 --> 00:04:57,659
VOICEMAIL:You have reached
Dr Adam Yuen.
88
00:04:57,699 --> 00:04:59,259
I am unable to take your call.
89
00:04:59,299 --> 00:05:01,139
Please leave a message
after the tone.
90
00:05:03,979 --> 00:05:06,459
Do you know what I don't understand?
91
00:05:06,499 --> 00:05:08,819
It was just a six-month placement,
92
00:05:08,859 --> 00:05:11,339
and his CV is impressive
enough without it.
93
00:05:11,379 --> 00:05:14,499
So, why did he risk his career
and lie about it?
94
00:05:17,459 --> 00:05:19,819
Has he lied about anything else?
95
00:05:19,859 --> 00:05:22,259
Everything else checks out.
96
00:05:22,299 --> 00:05:23,859
Are you sure about that?
97
00:05:27,339 --> 00:05:30,899
You have an injury over your
left eye and a wound on your neck.
98
00:05:32,459 --> 00:05:34,339
How do you account for them, Simi?
99
00:05:35,659 --> 00:05:37,099
Yeah, I got mugged.
100
00:05:37,139 --> 00:05:39,539
A kid with a knife. Really?
101
00:05:41,219 --> 00:05:43,579
And did you report the assault?
102
00:05:43,619 --> 00:05:46,179
No. Why not?
103
00:05:46,219 --> 00:05:47,659
What, are you going to catch him?
104
00:05:49,939 --> 00:05:53,179
He's answered your questions,
so unless you have other evidence?
105
00:06:06,659 --> 00:06:08,499
PHONE PINGS
106
00:06:16,499 --> 00:06:19,779
Tox results from the syringe
used in the attack on Wilfred.
107
00:06:19,819 --> 00:06:21,579
Here we go. Let's have a look.
108
00:06:26,699 --> 00:06:28,859
That's it?Midazolam?
109
00:06:31,139 --> 00:06:33,339
That's a sedative, isn't it?
110
00:06:33,379 --> 00:06:34,339
Yeah.
111
00:06:36,659 --> 00:06:40,619
The full syringe would have had
about five milligrams in it.
112
00:06:40,659 --> 00:06:41,779
That's not very much.
113
00:06:42,939 --> 00:06:46,859
So, either the assailant
is incompetent,
114
00:06:46,899 --> 00:06:49,179
or this wasn't intended to kill him.
115
00:06:50,659 --> 00:06:53,499
So, what's the aim?
116
00:06:53,539 --> 00:06:55,139
Kidnapping?
117
00:06:57,939 --> 00:06:59,979
HE SIGHS
118
00:07:00,019 --> 00:07:02,139
The guy's already ill.
119
00:07:02,179 --> 00:07:04,459
You know...
120
00:07:04,499 --> 00:07:08,379
If someone wanted him dead, it's not
going to be that hard, is it?
121
00:07:08,419 --> 00:07:09,699
He's got leukaemia.
122
00:07:11,579 --> 00:07:14,379
It would look like natural causes
if he died of sepsis.
123
00:07:17,059 --> 00:07:19,899
Should I get that syringe tested
again for bacteria?
124
00:07:26,779 --> 00:07:29,219
What's this about Mr Okoye
being moved?
125
00:07:29,259 --> 00:07:30,779
It's for his own safety.
126
00:07:30,819 --> 00:07:33,419
To the Cowley Institute?
And who's paying for that?
127
00:07:33,459 --> 00:07:36,339
Oh, I've been assured that they have
all the facilities required,
128
00:07:36,379 --> 00:07:39,139
and they've offered to do
the treatment free of charge.
129
00:07:39,179 --> 00:07:40,579
I will not allow it.
130
00:07:40,619 --> 00:07:43,819
Someone in your hospital is trying
to kill Mr Okoye.
131
00:07:45,339 --> 00:07:48,379
Quite frankly, Dr Braithwaite,
I don't need your permission.
132
00:08:01,139 --> 00:08:02,299
Haematology lab.
133
00:08:03,779 --> 00:08:05,739
Dr Braithwaite here.
134
00:08:05,779 --> 00:08:10,539
Wilfred Okoye, hospital number
1187266.
135
00:08:10,579 --> 00:08:13,019
I want all his stored blood
and marrow samples sent
136
00:08:13,059 --> 00:08:14,699
to my office immediately.
137
00:08:41,859 --> 00:08:43,979
Finished!
138
00:08:44,019 --> 00:08:48,739
79 needles swabbed and ready to go.
139
00:08:50,299 --> 00:08:52,659
You've got to see this.
140
00:08:52,699 --> 00:08:54,659
Microbiology results from
the syringe
141
00:08:54,699 --> 00:08:56,939
used in the attack on Wilfred.
142
00:08:56,979 --> 00:09:00,099
Turns out it is full of bacteria -
E coli.
143
00:09:01,899 --> 00:09:04,059
Well, it was lying around on
the floor.
144
00:09:04,099 --> 00:09:05,379
Could it be a contaminant?
145
00:09:05,419 --> 00:09:08,019
No. It's a pure growth -
just one type of bug in there.
146
00:09:08,059 --> 00:09:09,899
If it was a contaminant
you'd expect to see
147
00:09:09,939 --> 00:09:11,659
lots of different organisms.
148
00:09:11,699 --> 00:09:13,219
It's been created deliberately.
149
00:09:14,619 --> 00:09:18,299
So, what? The killer sneaks into
Wilfred's room pretending
150
00:09:18,339 --> 00:09:21,859
to be a nurse, inoculates him with
the bacteria,
151
00:09:21,899 --> 00:09:23,139
but adds a mild sedative...
152
00:09:25,419 --> 00:09:28,259
..so that when the real nurse comes
in with his medication,
153
00:09:28,299 --> 00:09:31,859
he's asleep and can't tell her that
someone else has already been in.
154
00:09:33,059 --> 00:09:34,699
He gets sepsis, he dies.
155
00:09:34,739 --> 00:09:36,179
Looks like natural causes.
156
00:09:37,819 --> 00:09:39,579
I need to tell DI Cracknell.
157
00:09:39,619 --> 00:09:42,059
You need to tell the doctors
looking after Wilfred.
158
00:09:46,379 --> 00:09:50,419
HEART MONITOR BEEPS
159
00:09:51,739 --> 00:09:53,899
HE BREATHES RAPIDLY
160
00:09:56,539 --> 00:09:59,139
ALARM SOUNDS
161
00:10:04,659 --> 00:10:06,499
HEART MONITOR BEEPS RAPIDLY
162
00:10:09,819 --> 00:10:11,939
HEART MONITOR FLATLINES
163
00:10:35,459 --> 00:10:38,339
It's as we expected - extensive
peripheral oedema,
164
00:10:38,379 --> 00:10:41,619
multiple organ failure,
consistent with sepsis.
165
00:10:41,659 --> 00:10:45,619
Yep. Toxicology shows only
medications used for his treatment,
166
00:10:45,659 --> 00:10:49,099
antibiotics, ceftriaxone,
gentamicin present
167
00:10:49,139 --> 00:10:50,859
in therapeutic concentrations.
168
00:10:50,899 --> 00:10:54,259
So, cause of death is consistent
with deliberate inoculation
169
00:10:54,299 --> 00:10:57,139
of the culture of E coli,
on a background
170
00:10:57,179 --> 00:11:00,499
of chemotherapy-induced
immune compromise.
171
00:11:00,539 --> 00:11:03,739
Well, we've got no other
leads on his attacker at present.
172
00:11:03,779 --> 00:11:05,939
We're liaising with
the Beninese Consulate to inform
173
00:11:05,979 --> 00:11:08,579
the family of the deceased.
174
00:11:08,619 --> 00:11:13,939
DNA says Wilfred Okoye was guilty of
Rahul's murder,
175
00:11:13,979 --> 00:11:16,339
but being unconscious,
had the perfect alibi.
176
00:11:18,019 --> 00:11:20,939
When a murder suspect gets murdered,
what does that mean?
177
00:11:20,979 --> 00:11:22,739
Framed by the real murderer?
178
00:11:22,779 --> 00:11:25,259
Why would you frame someone with
the perfect alibi?
179
00:11:31,579 --> 00:11:33,779
Simi Jacobs.
180
00:11:33,819 --> 00:11:35,379
What's his home address?
181
00:11:35,419 --> 00:11:36,379
Erm...
182
00:11:38,299 --> 00:11:42,059
Let's see. Flat 32, Bardwell House,
Lincoln Street.
183
00:11:42,099 --> 00:11:45,739
Thought so. Okoye and Jacobs have
been living together.
184
00:11:45,779 --> 00:11:48,899
Simi Jacobs has already been
released, guv.
185
00:11:48,939 --> 00:11:51,419
What? Yeah. Lack of forensics.
186
00:11:51,459 --> 00:11:52,979
All right.
187
00:11:53,019 --> 00:11:54,939
Might I suggest we pick
him up again?
188
00:12:02,139 --> 00:12:04,259
It still doesn't get us anywhere.
189
00:12:04,299 --> 00:12:05,979
It doesn't explain the DNA.
190
00:12:06,019 --> 00:12:08,299
And Simi was in custody
when Wilfred was attacked,
191
00:12:08,339 --> 00:12:09,699
so it doesn't even explain that.
192
00:12:09,739 --> 00:12:12,259
We're just going round in
circles.Yep.
193
00:12:23,179 --> 00:12:26,259
When he was interviewed,
Wilfred said his leukaemia
194
00:12:26,299 --> 00:12:29,019
was common in his region.
195
00:12:31,659 --> 00:12:32,939
Doesn't sound right to me.
196
00:12:47,979 --> 00:12:49,779
PHONE RINGS
197
00:12:49,819 --> 00:12:51,779
VOICEMAIL:You have reached
Dr Adam Yuen.
198
00:12:51,819 --> 00:12:53,299
I am unable to take your call.
199
00:12:53,339 --> 00:12:55,219
Please leave a message
after the tone.
200
00:12:58,139 --> 00:13:00,139
Wait there. He's not in, guv.
201
00:13:00,179 --> 00:13:01,899
And the neighbours haven't seen him.
202
00:13:01,939 --> 00:13:04,179
He's not been seen back at work
at the hospital either.
203
00:13:04,219 --> 00:13:06,979
You two stick around in case
he comes back.
204
00:13:07,019 --> 00:13:10,219
I'm sorry, guv. I should
have spotted the address.
205
00:13:12,099 --> 00:13:14,019
Don't worry about it.
206
00:13:14,059 --> 00:13:17,179
At least you didn't wrongly arrest
a bereaved cancer patient.
207
00:13:21,459 --> 00:13:23,019
I'll do that next time.
208
00:13:27,339 --> 00:13:28,339
Bye.
209
00:13:33,379 --> 00:13:35,499
Nine missed calls.
You're very persistent.
210
00:13:38,579 --> 00:13:40,139
I didn't want to end it like that.
211
00:13:42,859 --> 00:13:44,459
Can I help?
212
00:13:55,619 --> 00:13:58,619
You should have told me that
Emily Braithwaite is your godmother.
213
00:13:58,659 --> 00:14:00,419
Some godmother.
214
00:14:00,459 --> 00:14:03,059
No doubt you've received
the incriminating evidence about me.
215
00:14:03,099 --> 00:14:04,299
What evidence?
216
00:14:05,939 --> 00:14:08,739
She never sent it.
I should have guessed.
217
00:14:08,779 --> 00:14:11,779
If she tried to blackmail you,
then we'll make her answer for that.
218
00:14:11,819 --> 00:14:12,939
She's far too clever.
219
00:14:14,939 --> 00:14:17,859
Why do I think there's more to this
than you're telling me?
220
00:14:19,619 --> 00:14:21,779
No, I just lied to advance
my career.
221
00:14:21,819 --> 00:14:24,779
Really? Just to say you had a
fellowship. Why would you do that?
222
00:14:30,339 --> 00:14:31,939
My family are all doctors.
223
00:14:31,979 --> 00:14:33,939
I was always going to be a surgeon.
224
00:14:33,979 --> 00:14:35,539
It was more or less decided for me.
225
00:14:37,579 --> 00:14:40,659
Final year of medical school,
I was walking to uni
226
00:14:40,699 --> 00:14:43,899
and a cyclist is knocked off her
bike, right in front of me.
227
00:14:43,939 --> 00:14:45,699
Now, I was a keen student.
228
00:14:45,739 --> 00:14:48,819
I used to carry
a first aid kit around with me.
229
00:14:48,859 --> 00:14:52,459
If I'm honest, I was always waiting
for something like this.
230
00:14:52,499 --> 00:14:55,859
When I think about that it's
actually what I'm most ashamed of.
231
00:14:55,899 --> 00:14:58,139
She had facial injuries.
232
00:14:58,179 --> 00:15:00,779
Heavy, laboured breathing.
She was losing consciousness fast.
233
00:15:00,819 --> 00:15:02,779
So, I thought, "She's suffocating.
234
00:15:02,819 --> 00:15:07,059
"She needs a surgical airway,
a cricothyroidotomy."
235
00:15:07,099 --> 00:15:08,499
So, I made my incision.
236
00:15:08,539 --> 00:15:10,979
Something that I had
practised on mannequins.
237
00:15:11,019 --> 00:15:15,179
What I didn't know is that she had
an abnormal anatomy -
238
00:15:15,219 --> 00:15:18,499
an aberrant subclavian artery,
looping high in the neck.
239
00:15:19,739 --> 00:15:23,139
It's present in 1% of people
and 0% of mannequins.
240
00:15:23,179 --> 00:15:25,459
How could you have known?
It was a bloodbath.
241
00:15:33,099 --> 00:15:35,939
The artery retracted back into
her chest.
242
00:15:35,979 --> 00:15:38,539
There was nothing we could do
to save her.
243
00:15:38,579 --> 00:15:40,779
She bled to death in minutes.
244
00:15:45,179 --> 00:15:47,659
My father was furious.
245
00:15:49,379 --> 00:15:52,019
Not because I stupidly tried
a tracheostomy
246
00:15:52,059 --> 00:15:53,819
and killed an innocent young girl.
247
00:15:55,459 --> 00:15:59,219
But because I didn't study hard
enough to do it competently.
248
00:16:01,539 --> 00:16:05,939
So, he used his influence
and arranged for my fellowship
249
00:16:05,979 --> 00:16:07,579
as cover. For what?
250
00:16:11,659 --> 00:16:13,059
For my absence.
251
00:16:16,539 --> 00:16:19,699
It took months of therapy before
I could even leave the house.
252
00:16:28,579 --> 00:16:32,019
The irony in all of this is that
the one who helped me out
253
00:16:32,059 --> 00:16:33,819
the most was Emily Braithwaite.
254
00:16:35,259 --> 00:16:37,779
She visited me more often than
my parents.
255
00:16:40,779 --> 00:16:42,019
She understood.
256
00:16:45,019 --> 00:16:47,259
But there was no way I was going
to be a surgeon.
257
00:16:51,059 --> 00:16:53,619
So, I decided to choose pathology,
258
00:16:53,659 --> 00:16:57,459
and a false narrative was created as
to why I made the switch.
259
00:16:59,219 --> 00:17:02,019
When you start lying,
260
00:17:02,059 --> 00:17:04,339
you have to keep lying.
261
00:17:24,179 --> 00:17:26,179
Jack.Mm? I need to talk to you.
262
00:17:26,219 --> 00:17:27,539
Sure, what's up...?
263
00:17:30,099 --> 00:17:31,499
Hi.
264
00:17:31,539 --> 00:17:32,619
Are you kidding me?
265
00:17:36,019 --> 00:17:38,379
He doesn't work here any more
because he lied to us, do you
266
00:17:38,419 --> 00:17:41,059
remember? Do you remember that?
Adam's got a theory about Wilfred.
267
00:17:41,099 --> 00:17:42,659
Oh, right. Just hear him out.
268
00:17:42,699 --> 00:17:46,619
So, um, I just have to trust
him now?
269
00:17:46,659 --> 00:17:48,539
No, you've got to trust me.
270
00:17:52,459 --> 00:17:53,619
Think about it.
271
00:17:54,859 --> 00:17:57,579
Why would someone want Wilfred dead?
272
00:17:57,619 --> 00:17:59,899
What did he know that was such
a threat that someone
273
00:17:59,939 --> 00:18:00,899
had to kill him?
274
00:18:02,619 --> 00:18:06,019
Wilfred was being treated for acute
myeloid leukaemia.
275
00:18:06,059 --> 00:18:07,219
That's rare.
276
00:18:07,259 --> 00:18:09,699
Remember, he said there were
lots of other cases in his small
277
00:18:09,739 --> 00:18:11,899
village in Africa.
278
00:18:11,939 --> 00:18:14,699
What if Wilfred wasn't killed
because of what he knew?
279
00:18:14,739 --> 00:18:15,739
Don't follow.
280
00:18:15,779 --> 00:18:17,579
Wilfred wasn't the witness.
281
00:18:19,859 --> 00:18:21,059
He was the evidence.
282
00:18:24,699 --> 00:18:26,939
This is a trephine biopsy of
the bone marrow.
283
00:18:26,979 --> 00:18:30,779
We take a thin core of bone
with marrow cells in it.
284
00:18:30,819 --> 00:18:33,059
I've already taken an aspirate of
the fluids.
285
00:18:44,259 --> 00:18:47,699
So, the question is, why would so
many people from one place
286
00:18:47,739 --> 00:18:49,099
all get leukaemia?
287
00:18:50,339 --> 00:18:52,259
And that's going to tell you, is it?
288
00:18:52,299 --> 00:18:53,979
To be honest, I've never done
this before.
289
00:18:54,019 --> 00:18:56,059
Not postmortem, anyway.
290
00:18:56,099 --> 00:18:59,219
But you know what? It's crazy
enough for it to work. Mm-mm.
291
00:19:11,019 --> 00:19:12,019
Thanks.
292
00:19:14,099 --> 00:19:17,419
Oh, look. Here's a billion
DNA results from the needles.
293
00:19:19,099 --> 00:19:21,979
Want to give me a hand going
through these?
294
00:19:22,019 --> 00:19:23,099
Didn't think so.
295
00:19:41,179 --> 00:19:43,779
Nikki? The slide's ready when you
want to have a look.
296
00:19:52,259 --> 00:19:54,899
Good yield of cells.
More than I expected.
297
00:19:54,939 --> 00:19:57,339
Definitely acute myeloid leukaemia.
298
00:19:57,379 --> 00:20:00,779
It's not typical.
Looks more like secondary AML.
299
00:20:00,819 --> 00:20:03,499
Secondary to what?
A toxin of some sort.
300
00:20:03,539 --> 00:20:05,619
Some industrial chemical,
for example,
301
00:20:05,659 --> 00:20:09,499
or chemotherapy for
a different cancer.
302
00:20:09,539 --> 00:20:12,379
Right. And that can occur years
after the original exposure.
303
00:20:12,419 --> 00:20:14,419
Decades, in some cases.
304
00:20:14,459 --> 00:20:17,979
So, there may be other victims,
all exposed to the same thing?
305
00:20:20,019 --> 00:20:21,379
Makes sense.
306
00:20:23,059 --> 00:20:27,099
BUZZING
307
00:20:40,219 --> 00:20:41,379
Can I help you?
308
00:20:41,419 --> 00:20:43,419
They told me Wilfred is here.
309
00:20:43,459 --> 00:20:45,259
Can I see him, yeah?
310
00:20:45,299 --> 00:20:47,539
Er, you are?Family.
311
00:20:49,779 --> 00:20:51,339
Do you want to take a seat?
312
00:20:51,379 --> 00:20:54,579
Will I be able to sit with him
for a bit or...? I'll just check.
313
00:21:04,019 --> 00:21:06,419
I've found Rahul's murder weapon.
314
00:21:06,459 --> 00:21:10,019
One DNA profile matching Rahul,
one matching Wilfred,
315
00:21:10,059 --> 00:21:11,899
just like we found at the scene.
316
00:21:11,939 --> 00:21:13,859
But there's a third profile.
317
00:21:15,659 --> 00:21:17,779
Yep. Simi Jacobs.
318
00:21:17,819 --> 00:21:19,819
Simi? He's here!
319
00:21:19,859 --> 00:21:22,619
What do you mean he's here?
He wants to see Wilfred's body.
320
00:21:37,859 --> 00:21:40,539
This places Simi at the scene
of Rahul's murder.
321
00:21:40,579 --> 00:21:42,539
We need to keep him here.
322
00:21:42,579 --> 00:21:44,139
Call DI Cracknell.
323
00:21:48,099 --> 00:21:50,619
So, hang on.Simi Jacobs just
turned up at the lab.
324
00:21:50,659 --> 00:21:52,699
One needle injected into
three people.
325
00:21:52,739 --> 00:21:54,099
Better get down here.
326
00:21:54,139 --> 00:21:56,179
Simi had a puncture wound
to his neck.
327
00:21:56,219 --> 00:21:59,179
Rahul was stabbed in the chest,
but Wilfred?
328
00:21:59,219 --> 00:22:00,939
And if Simi got in a fight
with Rahul,
329
00:22:00,979 --> 00:22:02,899
why is Wilfred's blood spattered?
330
00:22:02,939 --> 00:22:05,499
Wilfred would have to have
been in the room as well.
331
00:22:05,539 --> 00:22:07,539
Maybe he was. Genetically speaking.
332
00:22:08,979 --> 00:22:11,459
What if that needle only stabbed
two people?
333
00:22:11,499 --> 00:22:14,259
Then one of them has two different
types of DNA. Exactly.
334
00:22:14,299 --> 00:22:15,859
Huh? No, for that to work, it would
335
00:22:15,899 --> 00:22:18,539
mean Simi's walking around with
Wilfred's blood inside him.
336
00:22:18,579 --> 00:22:20,419
That's ridiculous. Is it?
337
00:22:22,579 --> 00:22:25,659
Bone marrow transplant.
And Wilfred was the donor.
338
00:22:25,699 --> 00:22:29,499
So, Simi's blood has Wilfred's DNA.
339
00:22:37,059 --> 00:22:38,819
Do you want to come this way?Yeah.
340
00:22:43,259 --> 00:22:44,299
Just there.
341
00:22:47,379 --> 00:22:50,139
Can I get you a tea?
A glass of water or...?
342
00:22:50,179 --> 00:22:52,019
Oh, no, no!
343
00:22:52,059 --> 00:22:53,059
Thanks.
344
00:22:56,059 --> 00:22:58,339
You said that Wilfred was family?
345
00:22:58,379 --> 00:23:00,139
That's right.
346
00:23:00,179 --> 00:23:01,779
Was he a close relative?
347
00:23:03,419 --> 00:23:05,739
You ask a lot of questions.
348
00:23:05,779 --> 00:23:07,459
Remember me?
349
00:23:09,339 --> 00:23:11,299
I examined you at the station.
350
00:23:11,339 --> 00:23:12,659
I saw a scar on your chest.
351
00:23:12,699 --> 00:23:14,299
That's a Hickman line scar.
352
00:23:16,019 --> 00:23:18,219
Did you have a bone marrow
transplant as a kid?
353
00:23:19,699 --> 00:23:21,459
Yeah, I'm going to go.
354
00:23:21,499 --> 00:23:24,299
Simi, we found your blood at
the scene of Rahul's murder.
355
00:23:26,419 --> 00:23:27,539
Did you kill him?
356
00:23:30,459 --> 00:23:35,059
No, no, no. He... He came at me!
He was insane!
357
00:23:35,099 --> 00:23:36,339
It was an accident!
358
00:23:40,579 --> 00:23:42,179
I just wanted to protect Wilfred.
359
00:23:44,499 --> 00:23:47,179
Wilfred saved my life
when I was a kid.
360
00:23:47,219 --> 00:23:50,219
But you know what? He could only do
that because he was a match.
361
00:23:50,259 --> 00:23:53,099
People have transplants from their
brothers or mothers or whatever
362
00:23:53,139 --> 00:23:55,979
because they're a match.
I had no-one.
363
00:23:57,459 --> 00:24:00,459
How did you find him? There's this
charity attached to our church.
364
00:24:00,499 --> 00:24:02,499
They helped us get
the transplant records.
365
00:24:04,539 --> 00:24:06,139
Only it turns out Wilfred was sick.
366
00:24:07,379 --> 00:24:09,579
Were there others? Yeah.
367
00:24:09,619 --> 00:24:12,659
I mean, loads of people in his
village died from the same thing.
368
00:24:14,659 --> 00:24:16,259
We found Wilfred in time.
369
00:24:18,819 --> 00:24:20,259
So we thought.
370
00:24:22,219 --> 00:24:24,299
What?
371
00:24:24,339 --> 00:24:26,059
You're not going to let me see him?
372
00:24:30,179 --> 00:24:32,859
Simi.
373
00:24:32,899 --> 00:24:34,179
There he is.
374
00:24:54,699 --> 00:24:58,139
Ah, afternoon! Present from
DI Cracknell -
375
00:24:58,179 --> 00:25:00,899
all the rubbish from
Simi Jacobs' address.
376
00:25:00,939 --> 00:25:02,419
Thought you might want to take
a look
377
00:25:02,459 --> 00:25:04,259
in case you find anything relevant.
378
00:25:04,299 --> 00:25:08,539
Joy. Can I introduce Reverend Kanu?
You've already met Jack.
379
00:25:08,579 --> 00:25:12,619
This is Dr Nikki Alexander
and Dr Adam Yuen. Hello.
380
00:25:12,659 --> 00:25:16,019
Reverend Kanu runs the charitable
organisation that was responsible
381
00:25:16,059 --> 00:25:17,859
for bringing Wilfred to the UK.
382
00:25:17,899 --> 00:25:19,699
I have some photos from our trip.
383
00:25:19,739 --> 00:25:23,379
Sergeant Galloway thinks
they might help you. Thank you.
384
00:25:23,419 --> 00:25:25,859
I have to warn you,
they're not pretty.
385
00:25:29,099 --> 00:25:31,219
Tell me how Mr Okoye came to
be here.
386
00:25:32,899 --> 00:25:37,139
My church runs a charity that helps
arrange treatment in the UK.
387
00:25:37,179 --> 00:25:39,779
They raise money, get doctors to
volunteer, whatever.
388
00:25:41,299 --> 00:25:43,699
Wilfred's case was kind of special.
389
00:25:43,739 --> 00:25:47,339
I mean, he helped me years ago,
and now he needed my help.
390
00:25:47,379 --> 00:25:49,739
The local newspaper picked up
the story, it got a lot
391
00:25:49,779 --> 00:25:53,019
of publicity. So, the hospital
agreed to treat him.
392
00:25:53,059 --> 00:25:55,539
And he stayed at your flat? Yeah.
393
00:25:57,859 --> 00:26:00,659
Nobody told me he don't
speak English.
394
00:26:00,699 --> 00:26:03,579
I couldn't tell him anything.
395
00:26:03,619 --> 00:26:06,819
He didn't know who I was,
what he did for me.
396
00:26:09,139 --> 00:26:11,899
Then I learnt that he's under
the care of this Rahul guy.
397
00:26:13,779 --> 00:26:18,579
I have travelled widely in Africa
as part of my ministry,
398
00:26:18,619 --> 00:26:23,459
and yet nothing could have prepared
me for what we found in Bwendora.
399
00:26:26,339 --> 00:26:29,579
The town is remote, even by
African standards.
400
00:26:31,179 --> 00:26:34,419
There is only very basic
health care.
401
00:26:34,459 --> 00:26:37,059
It became clear there was a
lot of sickness.
402
00:26:38,939 --> 00:26:41,739
This man died within hours of
our arrival.
403
00:26:43,019 --> 00:26:47,339
The illness causes bleeding
and rashes. Fever sometimes.
404
00:26:47,379 --> 00:26:49,539
What do the people think it's
caused by?
405
00:26:49,579 --> 00:26:52,619
There's a large pesticide factory
in the town.
406
00:26:52,659 --> 00:26:55,739
Many people think the water has
been contaminated.
407
00:26:55,779 --> 00:26:58,659
They organised protests.
408
00:26:58,699 --> 00:27:01,659
People think there has been
a cover-up.
409
00:27:01,699 --> 00:27:04,099
But the factory provides
a lot of employment.
410
00:27:05,459 --> 00:27:09,179
It is a very divisive issue.
411
00:27:09,219 --> 00:27:13,819
The illness has ripped the heart
out of the community.
412
00:27:13,859 --> 00:27:16,899
There are very few families it has
left untouched.
413
00:27:16,939 --> 00:27:18,899
And they've had no outside help?
414
00:27:18,939 --> 00:27:22,179
There is one western charity
which runs a clinic,
415
00:27:22,219 --> 00:27:24,019
but they only visit every
few months.
416
00:27:26,659 --> 00:27:27,859
Some charity.
417
00:27:30,779 --> 00:27:32,779
Oh, Lord.
418
00:27:32,819 --> 00:27:34,739
Enlighten our minds with your truth.
419
00:27:37,099 --> 00:27:40,139
Give us the strength and the wisdom
to seek justice.
420
00:27:41,899 --> 00:27:45,739
Shine your everlasting light into
our darkness.
421
00:27:48,059 --> 00:27:51,419
There's a lot of talk about Rahul,
all around the hospital.
422
00:27:51,459 --> 00:27:53,939
How the hospital is protecting him.
423
00:27:53,979 --> 00:27:57,299
How he messed up an operation
and no-one wants to work with him.
424
00:27:57,339 --> 00:28:00,099
And you thought he shouldn't operate
on Wilfred.
425
00:28:00,139 --> 00:28:04,019
The night before, I heard him
arguing with this woman,
426
00:28:04,059 --> 00:28:06,179
Dr Braithwaite.
427
00:28:06,219 --> 00:28:08,299
She told Rahul not to do
the operation
428
00:28:08,339 --> 00:28:11,139
and he just told her that
she couldn't stop him.
429
00:28:11,179 --> 00:28:13,579
The bag of rubbish that we
found at your home address.
430
00:28:13,619 --> 00:28:15,619
Was it from one of the offices?
431
00:28:15,659 --> 00:28:17,019
Yeah. Which one?
432
00:28:18,099 --> 00:28:19,459
All of them.
433
00:28:19,499 --> 00:28:21,939
I was looking for
something, anything,
434
00:28:21,979 --> 00:28:23,699
I could use against Rahul.
435
00:28:23,739 --> 00:28:26,299
And on the morning of the operation?
436
00:28:26,339 --> 00:28:29,219
I saw Wilfred getting prepared for
theatre and I panicked.
437
00:28:29,259 --> 00:28:30,899
I phoned Rahul.
438
00:28:30,939 --> 00:28:32,499
What did you say?
439
00:28:32,539 --> 00:28:34,819
I told him I had some information
on him.
440
00:28:34,859 --> 00:28:38,939
I thought I could threaten to reveal
what I knew if he did the operation.
441
00:28:38,979 --> 00:28:40,179
What information?
442
00:28:42,699 --> 00:28:45,659
I was bluffing. But I had
to stop him.
443
00:28:48,939 --> 00:28:50,699
Well, you certainly managed that.
444
00:29:05,899 --> 00:29:07,379
How's it going?
445
00:29:07,419 --> 00:29:10,699
Oh, I'm in my element rummaging
through the trash. You know me.
446
00:29:11,899 --> 00:29:14,219
Nothing much here, apart from
a criminally lax attitude
447
00:29:14,259 --> 00:29:15,179
to recycling.
448
00:29:17,419 --> 00:29:19,459
Adam's still here, is he?
449
00:29:19,499 --> 00:29:21,419
We wouldn't have got this far
without him.
450
00:29:21,459 --> 00:29:23,019
I want to trust him.
451
00:29:25,539 --> 00:29:26,539
What's that?
452
00:29:31,619 --> 00:29:32,579
Oh, my God.
453
00:29:34,059 --> 00:29:38,659
This was in that rubbish bag you
found at Simi Jacobs' place.
454
00:29:38,699 --> 00:29:41,699
It's Harry Fletcher's ECG,
taken the day of his operation.
455
00:29:41,739 --> 00:29:43,139
It's normal.
456
00:29:43,179 --> 00:29:46,819
And this is the ECG that
appeared in Fletcher's notes.
457
00:29:46,859 --> 00:29:50,059
Same date and time,
but grossly abnormal.
458
00:29:50,099 --> 00:29:53,699
We believe they were switched
to deflect blame from Rahul
459
00:29:53,739 --> 00:29:56,139
after the operation went wrong.
460
00:29:56,179 --> 00:29:58,139
So, there was a cover-up?
461
00:29:58,179 --> 00:30:00,819
Well, what's this got to do with
the murder investigation?
462
00:30:00,859 --> 00:30:03,859
Yeah, Simi Jacobs admitted to
the attack on Arnie Rahul.
463
00:30:03,899 --> 00:30:06,699
I mean, he claims it was an accident
as a result of self-defence.
464
00:30:06,739 --> 00:30:08,339
That fits with the
crime scene findings.
465
00:30:08,379 --> 00:30:10,739
So, how does this transplant fit in?
466
00:30:10,779 --> 00:30:13,579
Well, Simi was born with
sickle cell disease,
467
00:30:13,619 --> 00:30:17,699
and was treated with a bone marrow
transplant at St Jude's as a child.
468
00:30:17,739 --> 00:30:20,459
Wilfred donated his stem cells
for Simi's transplant.
469
00:30:20,499 --> 00:30:22,739
20 years later,
Wilfred gets leukaemia.
470
00:30:22,779 --> 00:30:24,739
We don't think
this is a coincidence.
471
00:30:24,779 --> 00:30:27,939
He had a type of leukaemia
that can be caused by over-exposure
472
00:30:27,979 --> 00:30:29,259
to certain drugs.
473
00:30:29,299 --> 00:30:32,619
There's a technique known as
mobilisation,
474
00:30:32,659 --> 00:30:35,539
which is designed to increase
production of stem cells.
475
00:30:35,579 --> 00:30:39,619
Normally, stem cell donation
involves giving a perfectly safe
476
00:30:39,659 --> 00:30:41,219
bone marrow stimulant.
477
00:30:41,259 --> 00:30:46,139
But whoever did this also gave
Wilfred high levels of chemotherapy,
478
00:30:46,179 --> 00:30:47,939
and did so repeatedly.
479
00:30:47,979 --> 00:30:50,299
They gave chemo? To a volunteer?
480
00:30:50,339 --> 00:30:52,459
To yield even more stem cells.
481
00:30:52,499 --> 00:30:54,739
What for? More transplants?
482
00:30:54,779 --> 00:30:59,699
Stem cells have the ability to
develop into any type of body cell.
483
00:30:59,739 --> 00:31:01,659
Brain, heart, blood -
you name it.
484
00:31:01,699 --> 00:31:03,939
So there's a huge range
of potential therapies
485
00:31:03,979 --> 00:31:07,459
in which they can be used,
one of which is transplantation.
486
00:31:07,499 --> 00:31:12,179
About ten years ago, Braithwaite
and her team identified stem cells
487
00:31:12,219 --> 00:31:14,379
that were very special indeed,
488
00:31:14,419 --> 00:31:17,979
capable of being turned into
what are called killer T-cells,
489
00:31:18,019 --> 00:31:22,019
part of the immune system, which can
be made to attack malignant tumours.
490
00:31:22,059 --> 00:31:24,459
The potential for this discovery
was enormous.
491
00:31:24,499 --> 00:31:26,739
These magic cells
all had the same gene,
492
00:31:26,779 --> 00:31:30,979
a gene we think might be common
in Wilfred's town.
493
00:31:31,019 --> 00:31:34,859
They went looking for transplant
donors to treat people like Simi,
494
00:31:34,899 --> 00:31:37,579
but what they discovered
was something much bigger,
495
00:31:37,619 --> 00:31:39,779
so they went back for more,
and more.
496
00:31:39,819 --> 00:31:42,379
Basically they were flogging him
for every last stem cell
497
00:31:42,419 --> 00:31:44,819
he could produce.
Him and all the others.
498
00:31:44,859 --> 00:31:47,099
Wilfred's town was basically
a stem cell farm.
499
00:31:47,139 --> 00:31:50,499
Can you prove Wilfred
was given the stimulating drugs?
500
00:31:50,539 --> 00:31:53,739
It may be possible,
but that's way out of my league.
501
00:31:55,459 --> 00:31:57,259
Sounds like we need
a second opinion.
502
00:32:17,339 --> 00:32:18,659
Thank you, Professor.
503
00:32:18,699 --> 00:32:20,299
Not at all.
It's very good to see you.
504
00:32:20,339 --> 00:32:21,779
Thank you.
Oh, he's away!
505
00:32:23,659 --> 00:32:27,099
Adam, hello again.
Hello. This is Dr Nikki Alexander.
506
00:32:27,139 --> 00:32:29,379
Hello.How do you do?
And you've already met DI Cracknell.
507
00:32:29,419 --> 00:32:31,059
Yes, of course. This way.
508
00:32:32,019 --> 00:32:33,779
That was Alfie.
509
00:32:33,819 --> 00:32:37,859
He's one of our early trial patients
- osteosarcoma.
510
00:32:37,899 --> 00:32:39,899
When he was referred to us,
he was in a hospice
511
00:32:39,939 --> 00:32:43,499
on palliative treatment,
expected to die within weeks.
512
00:32:43,539 --> 00:32:45,939
Please. That was two years ago.
513
00:32:47,299 --> 00:32:48,619
He's now disease-free.
514
00:32:51,459 --> 00:32:54,939
We wanted to show you some
bone marrow samples from Mr Okoye.
515
00:32:54,979 --> 00:32:57,139
He was moved from St Jude's
to be treated here.
516
00:33:05,699 --> 00:33:07,499
Hmm.
517
00:33:07,539 --> 00:33:09,139
Secondary leukaemia.
518
00:33:12,139 --> 00:33:13,619
They look very unusual.
519
00:33:13,659 --> 00:33:16,459
Mr Okoye was a stem cell donor.
520
00:33:16,499 --> 00:33:18,139
Was he?
521
00:33:18,179 --> 00:33:21,339
We were wondering
if it might be stimulated.
522
00:33:21,379 --> 00:33:22,699
You mean Cyclo-G?
523
00:33:24,019 --> 00:33:25,579
Oh, dear.
524
00:33:25,619 --> 00:33:29,059
Yes, it's possible.
525
00:33:29,099 --> 00:33:32,059
Is there any way we can confirm it?
526
00:33:32,099 --> 00:33:34,859
You would need to look into
the genetics of his blood cells.
527
00:33:34,899 --> 00:33:36,979
There are some telltale signs.
528
00:33:37,019 --> 00:33:40,379
We have several world experts
in cytogenetics here.
529
00:33:40,419 --> 00:33:42,619
They'd be happy to help.
530
00:33:42,659 --> 00:33:45,619
Your cancer therapies are based
on Braithwaite's stem cell research,
531
00:33:45,659 --> 00:33:49,779
are they not?
Yes. Yes. I've never denied it.
532
00:33:49,819 --> 00:33:52,379
Hers was an extraordinary
piece of work.
533
00:33:53,619 --> 00:33:56,659
She tried for years to turn it into
a practical treatment,
534
00:33:56,699 --> 00:34:01,259
but, in the end, she was stumped
by the obvious problem.
535
00:34:01,299 --> 00:34:03,139
The limited supply of donors.
536
00:34:03,179 --> 00:34:04,379
Precisely.
537
00:34:04,419 --> 00:34:08,819
So, what we brought to the party
is called gene editing.
538
00:34:10,099 --> 00:34:13,699
We found a way of inserting
the special gene
539
00:34:13,739 --> 00:34:16,059
into any old stem cell,
and the result is...
540
00:34:17,219 --> 00:34:18,579
Well, you met Alfie.
541
00:34:19,819 --> 00:34:22,219
What is your relationship
to Emily Braithwaite?
542
00:34:23,819 --> 00:34:25,379
Yes.
543
00:34:25,419 --> 00:34:28,539
Well, I suppose you'd say
we're rivals.
544
00:34:28,579 --> 00:34:32,419
She's never forgiven me
for succeeding where she failed.
545
00:34:32,459 --> 00:34:36,339
But I'm afraid her star
has been waning for some time.
546
00:34:36,379 --> 00:34:37,699
What makes you say that?
547
00:34:40,099 --> 00:34:42,139
She came to ask for my help.
548
00:34:42,179 --> 00:34:45,779
Believe me,
that alone suggests desperation.
549
00:34:45,819 --> 00:34:49,579
She had just lost a very large
research grant.
550
00:34:49,619 --> 00:34:52,099
Is it possible that Braithwaite
poisoned Mr Okoye
551
00:34:52,139 --> 00:34:55,379
and everyone else in his town
to get more stem cells?
552
00:34:55,419 --> 00:34:58,179
That's a serious accusation.
553
00:34:58,219 --> 00:35:00,059
Everything's falling apart.
554
00:35:00,099 --> 00:35:02,459
So, like a gambler,
she risks more and more,
555
00:35:02,499 --> 00:35:05,099
desperate for that big win
to get herself back on top.
556
00:35:15,059 --> 00:35:20,539
THEY CONFER
557
00:35:23,819 --> 00:35:25,419
PHONE PINGS
558
00:36:00,619 --> 00:36:02,179
Now what?
Excuse me?
559
00:36:03,419 --> 00:36:06,579
You do realise my career is over?
And that's my fault?
560
00:36:06,619 --> 00:36:08,419
There's got to be a way out of this.
561
00:36:08,459 --> 00:36:09,699
You owe me that at least.
562
00:36:11,059 --> 00:36:13,659
You want Auntie Emily
to make it better?
563
00:36:15,259 --> 00:36:19,339
All those years I stuck up for you
with your father.
564
00:36:19,379 --> 00:36:22,299
You messed up. Again.
565
00:36:22,339 --> 00:36:24,139
For once in your life, own it.
566
00:36:26,379 --> 00:36:27,979
I don't get it.
567
00:36:28,019 --> 00:36:29,499
You and Rahul.
568
00:36:29,539 --> 00:36:31,619
You go to all these lengths
to protect his reputation,
569
00:36:31,659 --> 00:36:34,459
yet you show no interest
in who might have killed him.
570
00:36:34,499 --> 00:36:36,779
You don't even seem to even care
that he's dead!
571
00:36:38,299 --> 00:36:40,779
Maybe I've learnt to
bury my emotions.
572
00:36:42,659 --> 00:36:43,819
You should try it.
573
00:36:45,699 --> 00:36:47,899
You know they're onto you,
574
00:36:47,939 --> 00:36:50,539
and I'm not going to help you
this time.
575
00:36:50,579 --> 00:36:51,739
Oh, please.
576
00:36:53,419 --> 00:36:54,779
This is so painful.
577
00:37:01,579 --> 00:37:04,059
So, all roads lead to Braithwaite.
578
00:37:04,099 --> 00:37:06,379
Yes, but it's all circumstantial.
579
00:37:06,419 --> 00:37:09,019
There's nothing directly
connecting her to Wilfred.
580
00:37:09,059 --> 00:37:11,459
If you can find me something
concrete, I'll bring her in,
581
00:37:11,499 --> 00:37:13,259
but until then,
it's just speculation.
582
00:37:13,299 --> 00:37:15,699
Adam, where did you get to?
583
00:37:15,739 --> 00:37:18,299
Rahul's conduct during
Fletcher's operation amounted to
584
00:37:18,339 --> 00:37:20,259
criminal negligence.
585
00:37:20,299 --> 00:37:22,219
He could have been charged
for manslaughter.
586
00:37:22,259 --> 00:37:23,659
Well, he's dead.
587
00:37:23,699 --> 00:37:25,659
What if Braithwaite covered it up?
588
00:37:25,699 --> 00:37:28,099
That's attempting to pervert
the course of justice.
589
00:37:28,139 --> 00:37:29,579
Which means you can arrest her.
590
00:37:29,619 --> 00:37:32,699
Oh, and how do we know that
Braithwaite swaps the ECG?
591
00:37:32,739 --> 00:37:35,019
We can't. There are several
sets of prints on the trace,
592
00:37:35,059 --> 00:37:36,619
one of which could be Braithwaite's.
593
00:37:36,659 --> 00:37:39,099
Exactly, so we can't just arrest her
on the off-chance that
594
00:37:39,139 --> 00:37:40,499
her prints are on there.
I know.
595
00:37:40,539 --> 00:37:41,939
ADAM:I met her for a drink.
596
00:37:45,979 --> 00:37:47,819
Her prints are on this glass.
597
00:37:47,859 --> 00:37:51,059
When you find that they are
the same as the sets on the ECG,
598
00:37:51,099 --> 00:37:53,699
then you can arrest her.
That's not admissible as evidence!
599
00:37:53,739 --> 00:37:55,339
It doesn't have to be.
600
00:37:57,019 --> 00:38:00,219
How do we know for sure
she touched this glass?
601
00:38:00,259 --> 00:38:02,459
Well, you're just going to
have to trust me.
602
00:38:49,179 --> 00:38:50,579
You two go round the back.
603
00:38:54,619 --> 00:38:56,019
DOORBELL RINGS
604
00:39:02,259 --> 00:39:04,299
Her car's here.
Looks like she's home.
605
00:39:07,419 --> 00:39:08,459
No letterbox.
606
00:39:12,939 --> 00:39:14,299
Dr Braithwaite?
607
00:39:15,419 --> 00:39:17,579
DS Galloway.
Could you open the door, please?
608
00:39:22,139 --> 00:39:24,099
Police!
Dr Braithwaite?
609
00:39:36,219 --> 00:39:37,299
Shit.
610
00:39:43,659 --> 00:39:45,219
No sign of external injury.
611
00:39:47,099 --> 00:39:50,499
Both front and back doors
were locked from the inside.
612
00:39:50,539 --> 00:39:53,139
There's no signs
of forced entry.
613
00:39:53,179 --> 00:39:54,539
Everything's neat and tidy.
614
00:39:56,779 --> 00:39:58,059
Sudden chest pain, maybe?
615
00:39:59,699 --> 00:40:00,699
Or suicide.
616
00:40:33,219 --> 00:40:36,019
Nikki. Adam. Look at these.
617
00:40:41,539 --> 00:40:44,739
Two samples
with Wilfred Okoye's name on.
618
00:41:07,739 --> 00:41:09,739
Look at this.
619
00:41:09,779 --> 00:41:11,979
The boiler's locked out.
620
00:41:12,019 --> 00:41:13,899
Yeah. Mine does that all the time.
621
00:41:13,939 --> 00:41:15,019
Bloody things.
622
00:41:53,579 --> 00:41:56,059
Heart weighs 380g.
623
00:42:22,259 --> 00:42:25,059
Evidence of left ventricular
hypertrophy.
624
00:42:26,539 --> 00:42:27,939
Valves unremarkable.
625
00:42:31,259 --> 00:42:35,019
Left anterior descending
coronary artery.
626
00:42:35,059 --> 00:42:38,099
Moderate stenosis,
no evidence of thrombus.
627
00:42:46,579 --> 00:42:49,179
The toxicology
was entirely negative,
628
00:42:49,219 --> 00:42:51,739
apart from a modest level
of alcohol.
629
00:42:51,779 --> 00:42:55,779
No paracetamol,
no benzodiazepines, nothing.
630
00:42:55,819 --> 00:42:59,339
So this, together with the absence
of pills and containers
631
00:42:59,379 --> 00:43:02,259
at the address, and the absence
of any needle marks on the body,
632
00:43:02,299 --> 00:43:05,419
leads me to conclude that death
was not as a result
633
00:43:05,459 --> 00:43:08,019
of suicide or poisoning.
634
00:43:08,059 --> 00:43:11,419
In fact, the only significant
finding from the postmortem
635
00:43:11,459 --> 00:43:14,459
examination is moderate ischaemic
heart disease,
636
00:43:14,499 --> 00:43:17,859
together with hypertrophy of the
septum and left ventricular wall.
637
00:43:17,899 --> 00:43:20,859
But no evidence of
coronary thrombosis?
638
00:43:20,899 --> 00:43:23,819
The ventricular wall thickness...
Heart attack. ..and the degree
639
00:43:23,859 --> 00:43:27,499
of myocardial disarray on microscopy
are borderline
640
00:43:27,539 --> 00:43:29,699
for a diagnosis of HCM.
641
00:43:29,739 --> 00:43:32,539
What's that?
Hypertrophic cardiomyopathy.
642
00:43:32,579 --> 00:43:35,939
It's an inherited heart condition
that can lead to sudden death.
643
00:43:35,979 --> 00:43:37,819
Fabrice Muamba.
Yes.
644
00:43:39,699 --> 00:43:43,419
Bolton Wanderers versus Tottenham.
FA Cup quarterfinal, 2012.
645
00:43:43,459 --> 00:43:45,339
He collapsed on the pitch.
Nearly died.
646
00:43:45,379 --> 00:43:47,219
Well, technically he did.
647
00:43:47,259 --> 00:43:49,339
In cases of high stress or exercise,
648
00:43:49,379 --> 00:43:53,459
the heart can lead into an abnormal
rhythm, which can be fatal.
649
00:43:53,499 --> 00:43:56,259
And Emily Braithwaite
was under a lot of stress.
650
00:43:56,299 --> 00:44:00,859
So it is possible that this caused
a dysrhythmic event...
651
00:44:00,899 --> 00:44:03,619
Heart attack. ..that led to
her death, don't you think?
652
00:44:07,739 --> 00:44:09,699
How come she didn't have
a letterbox?
653
00:44:09,739 --> 00:44:11,939
It's a passive house.
It's so well-insulated,
654
00:44:11,979 --> 00:44:14,579
it doesn't need heating.
You heat it up just by living in it.
655
00:44:14,619 --> 00:44:16,419
But it has to be really airtight.
656
00:44:16,459 --> 00:44:18,579
It's like living in a bubble.
657
00:44:18,619 --> 00:44:21,699
All the air goes in and out through
a single ventilation system.
658
00:44:23,339 --> 00:44:26,339
But why would the boiler lock out?
659
00:44:26,379 --> 00:44:30,739
What if it was faulty and produced
a lot of carbon monoxide?
660
00:44:30,779 --> 00:44:33,059
No carbon monoxide in
the toxicology.
661
00:44:37,419 --> 00:44:39,939
She's a suspect in a murder case.
She conveniently dies.
662
00:44:39,979 --> 00:44:41,779
What if others were involved?
663
00:44:41,819 --> 00:44:43,979
If you can tell me how they did it,
I'll believe you,
664
00:44:44,019 --> 00:44:47,499
but until then,
it's looking like natural causes.
665
00:44:47,539 --> 00:44:51,099
Right, then, provisional assumption
is that Braithwaite
666
00:44:51,139 --> 00:44:53,779
was guilty of conspiracy
to murder Wilfred Okoye,
667
00:44:53,819 --> 00:44:56,659
as well as perverting the course
of justice in the Fletcher case.
668
00:44:56,699 --> 00:44:57,899
What about Simi?
669
00:44:57,939 --> 00:45:01,899
That's up to the CPS, whether
they buy a self-defence plea.
670
00:45:01,939 --> 00:45:03,459
I'll keep you posted.
671
00:45:21,459 --> 00:45:23,699
So this is where you've been hiding.
672
00:45:25,899 --> 00:45:27,739
Adam told you, then?
673
00:45:27,779 --> 00:45:30,299
Oh, yeah. He told me everything.
674
00:46:26,659 --> 00:46:28,059
I don't get it.
675
00:46:28,099 --> 00:46:31,059
How could someone like Braithwaite
justify it to herself,
676
00:46:31,099 --> 00:46:32,419
let alone anyone else?
677
00:46:32,459 --> 00:46:34,899
They get fixated on the prize,
don't they?
678
00:46:34,939 --> 00:46:38,459
The breakthrough, and all
the acclaim that goes with it.Mm.
679
00:46:39,619 --> 00:46:42,699
Did you ever want to do something
like that? Fancy research job?
680
00:46:43,779 --> 00:46:45,539
I think you'd be really good
at that.
681
00:46:48,579 --> 00:46:49,539
I don't know.
682
00:46:50,659 --> 00:46:52,499
It's more Adam's world.
Mm.
683
00:46:53,779 --> 00:46:54,859
Not any more.
684
00:46:56,619 --> 00:46:59,299
You can see how liberated he's been.
685
00:46:59,339 --> 00:47:02,499
He's carried that secret around
for so long.
686
00:47:02,539 --> 00:47:05,979
Well, he's stopped trying to
be all things to all men.
687
00:47:06,019 --> 00:47:08,859
And I'll tell you,
he loves beating himself up.
688
00:48:08,419 --> 00:48:11,819
Hi. I'm working on the case
of Wilfred Okoye.
689
00:48:11,859 --> 00:48:14,139
I was wondering if I could get
his microbiology results
690
00:48:14,179 --> 00:48:15,579
from his stay here.
691
00:48:15,619 --> 00:48:18,059
Date of birth is 9/7/66.
692
00:48:23,459 --> 00:48:25,939
I just need to, er,
speak to my supervisor.
693
00:48:25,979 --> 00:48:27,259
OK. Thank you.
694
00:49:05,099 --> 00:49:06,859
PHONE PINGS
695
00:49:06,899 --> 00:49:08,539
It's Adam.
696
00:49:10,779 --> 00:49:12,259
"We were wrong about everything.
697
00:49:14,459 --> 00:49:17,019
"At Cowley Institute. Come quickly."
What?
698
00:49:20,419 --> 00:49:22,299
What are we looking at?
699
00:49:22,339 --> 00:49:25,099
Wilfred's blood cultures.
Microbiology report.
700
00:49:28,019 --> 00:49:29,219
Hang on.
701
00:49:30,619 --> 00:49:34,219
The antibiotic sensitivities
have been reversed.
702
00:49:34,259 --> 00:49:35,739
Who's done that? Braithwaite?
703
00:49:35,779 --> 00:49:38,299
Couldn't be. These are from
the Cowley institute.
704
00:49:40,939 --> 00:49:42,579
Adam needs us. Come on.
705
00:50:12,139 --> 00:50:13,579
SHE SIGHS
706
00:50:13,619 --> 00:50:16,379
Oh, great. We were supposed to
go left back at the lights.
707
00:50:30,619 --> 00:50:32,139
CAR DOOR OPENS
708
00:50:33,859 --> 00:50:34,859
Dr Yuen?
709
00:50:34,899 --> 00:50:38,099
You know Emily Braithwaite
died yesterday?
710
00:50:38,139 --> 00:50:42,339
What? Uh, no. How did it happen?
711
00:50:42,379 --> 00:50:45,499
Unknown. Found dead in a house
that was bolted from the inside.
712
00:50:47,059 --> 00:50:49,579
Oh, look, an oxygen analyser.
713
00:50:51,019 --> 00:50:52,819
Do you always keep one of those
in your car?
714
00:50:52,859 --> 00:50:54,699
I use it for various things.
715
00:50:54,739 --> 00:50:57,979
So Emily died just as
you convinced us she was guilty.
716
00:50:58,019 --> 00:51:00,739
Her work was based on exploitation.
717
00:51:00,779 --> 00:51:02,859
Well, she can't deny that now,
can she?
718
00:51:02,899 --> 00:51:04,299
Well, whatever happened,
719
00:51:04,339 --> 00:51:07,539
I'm sure forensic science
will find the answer.
720
00:51:07,579 --> 00:51:10,979
Mm. Then I realised just how much
liquid nitrogen you go through here.
721
00:51:11,019 --> 00:51:13,019
Two deliveries in three days?
722
00:51:15,259 --> 00:51:18,579
I mean,
that is some evil genius stuff.
723
00:51:18,619 --> 00:51:20,739
Pretty quick and very clean.
724
00:51:20,779 --> 00:51:24,259
Except the pilot light in the boiler
went out at Braithwaite's house.
725
00:51:24,299 --> 00:51:25,699
Otherwise, the perfect crime.
726
00:51:26,939 --> 00:51:28,459
Are you insane?
727
00:51:28,499 --> 00:51:31,379
Oh, sorry. That's forensic science.
Get out.
728
00:51:35,739 --> 00:51:38,379
Braithwaite had Wilfred's
blood samples. She was onto you.
729
00:51:39,659 --> 00:51:41,459
My research is changing lives.
730
00:51:41,499 --> 00:51:43,099
She never made the crucial
breakthrough,
731
00:51:43,139 --> 00:51:44,739
but then again, neither did you.
732
00:51:44,779 --> 00:51:46,899
You reckon you'll crack it
any minute now, don't you?
733
00:51:46,939 --> 00:51:49,379
You just have to keep going,
keep blasting innocent men
734
00:51:49,419 --> 00:51:51,859
and women with poisonous drugs,
and then you'll get there.
735
00:51:51,899 --> 00:51:54,659
You know nothing. There's no
gene editing going on here.
736
00:51:54,699 --> 00:51:57,059
Your magic treatments are all
from stem cells that you get
737
00:51:57,099 --> 00:51:58,539
from killing people like Wilfred.
738
00:51:58,579 --> 00:52:02,179
When childhood cancer is
a thing of the past thanks to me,
739
00:52:02,219 --> 00:52:04,419
no-one will care.
740
00:52:04,459 --> 00:52:07,019
That's what it's all about,
isn't it?
741
00:52:07,059 --> 00:52:11,539
It's not about the money or
the power. It's about the prestige.
742
00:52:13,219 --> 00:52:15,779
So what are you going to do
about it, Adam?
743
00:52:15,819 --> 00:52:17,739
Mm? You're discredited.
744
00:52:17,779 --> 00:52:19,219
You're getting struck off.
745
00:52:20,499 --> 00:52:23,099
Of course I know!
746
00:52:23,139 --> 00:52:24,179
I know everything.
747
00:52:26,819 --> 00:52:29,179
You've no idea
who you're dealing with.
748
00:52:31,699 --> 00:52:32,859
Adam?
749
00:52:35,179 --> 00:52:36,099
Adam!
750
00:52:38,579 --> 00:52:42,059
PHONE RINGS
751
00:52:42,099 --> 00:52:44,619
Adam? What's happening?
752
00:52:44,659 --> 00:52:48,059
Cowley's the one exploiting Wilfred
and the rest of the donors.
753
00:52:48,099 --> 00:52:50,219
And he killed Braithwaite
with liquid nitrogen.
754
00:52:50,259 --> 00:52:52,339
He poured it in the vent
of her airtight house,
755
00:52:52,379 --> 00:52:55,819
turning it into a gas chamber.
She suffocated.
756
00:52:55,859 --> 00:52:58,819
Cowley did a deal with Rahul
to kill Wilfred during surgery.
757
00:52:58,859 --> 00:53:01,699
And when that failed, he attacked
Wilfred with the bacteria...
758
00:53:04,099 --> 00:53:06,299
..to make sure he switched
the micro reports
759
00:53:06,339 --> 00:53:08,299
so that the antibiotics
wouldn't work.
760
00:53:08,339 --> 00:53:10,219
ENGINE REVS
761
00:53:21,659 --> 00:53:22,819
Adam?
762
00:53:24,099 --> 00:53:25,299
Adam!
763
00:53:34,979 --> 00:53:36,419
HE COUGHS
764
00:53:44,979 --> 00:53:48,739
I'm sure that's Cowley.
Really? Call Cracknell.
765
00:53:48,779 --> 00:53:50,859
But...
Get after him. I'll find Adam.
766
00:53:59,499 --> 00:54:03,459
Yeah, I'm heading north
on Colbridge Road.
767
00:54:03,499 --> 00:54:06,299
It's a black Mercedes.
768
00:54:06,339 --> 00:54:07,539
Adam?
769
00:54:07,579 --> 00:54:08,739
Adam!
770
00:54:08,779 --> 00:54:10,099
Oh, Jesus.
771
00:54:13,459 --> 00:54:15,019
Ambulance.
772
00:54:15,059 --> 00:54:18,219
SIRENS WAIL
773
00:54:21,139 --> 00:54:23,339
Can you hear me? Adam?
774
00:54:23,379 --> 00:54:25,819
You took your time, mate.
775
00:54:25,859 --> 00:54:27,179
Come to take all the credit?
776
00:54:29,059 --> 00:54:30,379
Oh, man.
777
00:54:31,939 --> 00:54:34,539
The ambulance is on its way.
What happened?
778
00:54:34,579 --> 00:54:35,739
I messed up.
779
00:54:52,019 --> 00:54:53,019
You trusted me.
780
00:54:56,899 --> 00:54:57,899
That means a lot.
781
00:54:59,939 --> 00:55:02,459
Adam. Adam, stay with me.
782
00:55:02,499 --> 00:55:04,779
Adam. Come on, man. Stay with me.
Stay with me.
783
00:55:04,819 --> 00:55:05,979
Come on! Adam!
784
00:55:07,259 --> 00:55:08,379
Adam!
785
00:55:26,579 --> 00:55:30,379
SIREN WAILS
786
00:55:55,419 --> 00:55:56,419
Oh, God.
787
00:56:03,539 --> 00:56:04,899
Oh, no.
788
00:56:09,499 --> 00:56:13,179
SHE SOBS
789
00:56:37,139 --> 00:56:43,459
# Testator silens
790
00:56:46,339 --> 00:56:53,059
# Costestes e spiritu
791
00:56:53,099 --> 00:56:59,579
# Silencium. #
88864
Can't find what you're looking for?
Get subtitles in any language from opensubtitles.com, and translate them here.