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Would you like to inspect the original subtitles? These are the user uploaded subtitles that are being translated: 1 00:00:02,579 --> 00:00:05,779 This programme contains some scenes which some viewers may find upsetting 2 00:00:05,819 --> 00:00:08,259 Victim is Mr Arnie Rahul. Consultant surgeon. 48 years of age. 3 00:00:08,299 --> 00:00:11,059 Good reputation, though he's fallen out with a few people recently. 4 00:00:11,099 --> 00:00:13,259 {\an8}He was about to start an operation. He gets a phone call. 5 00:00:13,299 --> 00:00:14,499 Walks out, never comes back. 6 00:00:14,539 --> 00:00:16,939 Single puncture wound to the left chest wall. 7 00:00:18,299 --> 00:00:21,019 What's that in his hand? Looks like a syringe and needle. 8 00:00:21,059 --> 00:00:24,259 It's a Hickman line. A long-term vascular access device 9 00:00:24,299 --> 00:00:26,779 for people who need chemotherapy or blood transfusions. 10 00:00:26,819 --> 00:00:29,539 The assailant would have had extensive cross contamination 11 00:00:29,579 --> 00:00:30,939 with the victim's blood. 12 00:00:30,979 --> 00:00:33,179 Stick that in to a big artery and blood will flow out 13 00:00:33,219 --> 00:00:34,659 like a high-pressure hose. 14 00:00:34,699 --> 00:00:36,019 Simi Jacobs. 15 00:00:37,139 --> 00:00:38,499 He's denying everything. 16 00:00:39,539 --> 00:00:42,739 Simi Jacobs is not a match 17 00:00:42,779 --> 00:00:44,419 to the blood spatter at the scene. 18 00:00:44,459 --> 00:00:46,739 So, who is it? It's Wilfred Okoye. 19 00:00:46,779 --> 00:00:47,819 The patient? 20 00:00:47,859 --> 00:00:51,539 Arnie Rahul was murdered by a man who was under general anaesthetic 21 00:00:51,579 --> 00:00:53,059 in a different room? 22 00:00:53,099 --> 00:00:56,579 Blood alcohol level, three times the legal driving limit. 23 00:00:56,619 --> 00:00:59,019 You said he shouldn't be operating. 24 00:00:59,059 --> 00:01:01,019 Not after the Harry Fletcher incident. 25 00:01:01,059 --> 00:01:03,899 Arrested on the table during surgery last week. 26 00:01:03,939 --> 00:01:06,499 I want you to do the postmortem. 27 00:01:06,539 --> 00:01:08,739 Technically that would be a conflict of interest. 28 00:01:08,779 --> 00:01:12,059 Summarising postmortem examination, Harry Fletcher. 29 00:01:12,099 --> 00:01:13,979 What are you doing? My colleagues are here. 30 00:01:14,019 --> 00:01:16,859 Is that Emily Braithwaite? She's Adam's godmother. 31 00:01:16,899 --> 00:01:19,059 You'd think he might have mentioned it. 32 00:01:19,099 --> 00:01:21,539 Are you going to confront him? Not yet. 33 00:01:21,579 --> 00:01:23,979 Your original stem cell work was brilliant. 34 00:01:24,019 --> 00:01:27,819 But you tried and failed to turn it into a viable cancer treatment. 35 00:01:27,859 --> 00:01:30,419 Wilfred Okoye, still in the hospital. 36 00:01:30,459 --> 00:01:32,099 What's he going to know? 37 00:01:32,139 --> 00:01:35,139 You won't find out unless you ask him. 38 00:01:35,179 --> 00:01:37,979 Mr Fletcher died because of surgical error. 39 00:01:38,019 --> 00:01:41,459 Adam! You have no idea what you've done. 40 00:01:41,499 --> 00:01:44,019 When I applied for this job I falsified my CV, 41 00:01:44,059 --> 00:01:45,899 and Emily Braithwaite tried to use this 42 00:01:45,939 --> 00:01:48,139 fact to influence my findings in the Fletcher Case. 43 00:01:48,179 --> 00:01:49,739 Here's my letter of resignation. 44 00:01:49,779 --> 00:01:51,099 Effective immediately. 45 00:01:52,619 --> 00:01:58,699 {\an8}# Testator silens 46 00:02:01,179 --> 00:02:08,339 # Costestes e spiritu 47 00:02:08,379 --> 00:02:15,779 # Silencium 48 00:02:23,139 --> 00:02:28,979 # Testator silens. # 49 00:02:35,099 --> 00:02:37,699 DISTANT SIREN 50 00:02:40,539 --> 00:02:44,019 Wilfred Okoye, a Beninese farm worker, was admitted 51 00:02:44,059 --> 00:02:48,299 to St Jude's hospital for the treatment of leukaemia a week ago. 52 00:02:48,339 --> 00:02:51,579 Although he lost consciousness briefly during the attack 53 00:02:51,619 --> 00:02:55,339 on his life last night, he seems to have recovered with no ill effects. 54 00:02:55,379 --> 00:02:59,619 Awaiting toxicology from the syringe we believe was used in the attack. 55 00:02:59,659 --> 00:03:01,419 Prints? Fibres? 56 00:03:01,459 --> 00:03:03,699 Nothing conclusive. We're interviewing witnesses 57 00:03:03,739 --> 00:03:05,859 but no-one got a good look at the attacker. 58 00:03:05,899 --> 00:03:08,379 How come he's being treated here in the UK? 59 00:03:08,419 --> 00:03:12,139 It was set up by a charity, and then arranged through Rahul. 60 00:03:13,859 --> 00:03:18,099 Here is a man who has lived his entire life in Benin 61 00:03:18,139 --> 00:03:22,219 up until a week ago, and, according to our DNA evidence, 62 00:03:22,259 --> 00:03:26,459 murders his surgeon while under anaesthetic in a different room. 63 00:03:30,179 --> 00:03:35,699 Could the DNA at the murder scene been a contaminant or planted? 64 00:03:35,739 --> 00:03:38,419 No. The spatter patterns are too perfect. 65 00:03:38,459 --> 00:03:40,779 It came from someone who was in the room at the time. 66 00:03:40,819 --> 00:03:42,499 So, how do you explain it? 67 00:03:45,819 --> 00:03:48,819 How do we know Wilfred was anaesthetised? 68 00:03:48,859 --> 00:03:51,619 I mean, how do we know it was him? 69 00:03:51,659 --> 00:03:53,299 What, he's got an identical twin? 70 00:03:53,339 --> 00:03:54,779 Bit fantastical, Steve. 71 00:03:54,819 --> 00:03:56,499 I don't know. 72 00:03:56,539 --> 00:03:58,139 There's another explanation. 73 00:04:00,259 --> 00:04:02,419 DNA samples got mixed up. 74 00:04:02,459 --> 00:04:04,459 Ah! No way! 75 00:04:04,499 --> 00:04:07,579 Look, I'm just putting it out there. Mm-mn. We could run the test again. 76 00:04:07,619 --> 00:04:09,499 Those samples were handled correctly. 77 00:04:11,059 --> 00:04:13,179 Jack, shall we just run them again? 78 00:04:16,499 --> 00:04:18,259 Right, yep. Good. 79 00:04:19,539 --> 00:04:20,539 OK. 80 00:04:21,739 --> 00:04:23,739 Let me know when toxicology comes back. 81 00:04:32,059 --> 00:04:35,539 So, the samples got mixed up, did they? It's always possible. 82 00:04:35,579 --> 00:04:36,539 Mm-hm. 83 00:04:37,619 --> 00:04:40,779 You know who took the swab from Simi Jacobs. Adam. 84 00:04:42,259 --> 00:04:43,539 What are you suggesting? 85 00:04:45,539 --> 00:04:46,979 Just saying. 86 00:04:53,499 --> 00:04:55,819 PHONE RINGS 87 00:04:55,859 --> 00:04:57,659 VOICEMAIL:You have reached Dr Adam Yuen. 88 00:04:57,699 --> 00:04:59,259 I am unable to take your call. 89 00:04:59,299 --> 00:05:01,139 Please leave a message after the tone. 90 00:05:03,979 --> 00:05:06,459 Do you know what I don't understand? 91 00:05:06,499 --> 00:05:08,819 It was just a six-month placement, 92 00:05:08,859 --> 00:05:11,339 and his CV is impressive enough without it. 93 00:05:11,379 --> 00:05:14,499 So, why did he risk his career and lie about it? 94 00:05:17,459 --> 00:05:19,819 Has he lied about anything else? 95 00:05:19,859 --> 00:05:22,259 Everything else checks out. 96 00:05:22,299 --> 00:05:23,859 Are you sure about that? 97 00:05:27,339 --> 00:05:30,899 You have an injury over your left eye and a wound on your neck. 98 00:05:32,459 --> 00:05:34,339 How do you account for them, Simi? 99 00:05:35,659 --> 00:05:37,099 Yeah, I got mugged. 100 00:05:37,139 --> 00:05:39,539 A kid with a knife. Really? 101 00:05:41,219 --> 00:05:43,579 And did you report the assault? 102 00:05:43,619 --> 00:05:46,179 No. Why not? 103 00:05:46,219 --> 00:05:47,659 What, are you going to catch him? 104 00:05:49,939 --> 00:05:53,179 He's answered your questions, so unless you have other evidence? 105 00:06:06,659 --> 00:06:08,499 PHONE PINGS 106 00:06:16,499 --> 00:06:19,779 Tox results from the syringe used in the attack on Wilfred. 107 00:06:19,819 --> 00:06:21,579 Here we go. Let's have a look. 108 00:06:26,699 --> 00:06:28,859 That's it?Midazolam? 109 00:06:31,139 --> 00:06:33,339 That's a sedative, isn't it? 110 00:06:33,379 --> 00:06:34,339 Yeah. 111 00:06:36,659 --> 00:06:40,619 The full syringe would have had about five milligrams in it. 112 00:06:40,659 --> 00:06:41,779 That's not very much. 113 00:06:42,939 --> 00:06:46,859 So, either the assailant is incompetent, 114 00:06:46,899 --> 00:06:49,179 or this wasn't intended to kill him. 115 00:06:50,659 --> 00:06:53,499 So, what's the aim? 116 00:06:53,539 --> 00:06:55,139 Kidnapping? 117 00:06:57,939 --> 00:06:59,979 HE SIGHS 118 00:07:00,019 --> 00:07:02,139 The guy's already ill. 119 00:07:02,179 --> 00:07:04,459 You know... 120 00:07:04,499 --> 00:07:08,379 If someone wanted him dead, it's not going to be that hard, is it? 121 00:07:08,419 --> 00:07:09,699 He's got leukaemia. 122 00:07:11,579 --> 00:07:14,379 It would look like natural causes if he died of sepsis. 123 00:07:17,059 --> 00:07:19,899 Should I get that syringe tested again for bacteria? 124 00:07:26,779 --> 00:07:29,219 What's this about Mr Okoye being moved? 125 00:07:29,259 --> 00:07:30,779 It's for his own safety. 126 00:07:30,819 --> 00:07:33,419 To the Cowley Institute? And who's paying for that? 127 00:07:33,459 --> 00:07:36,339 Oh, I've been assured that they have all the facilities required, 128 00:07:36,379 --> 00:07:39,139 and they've offered to do the treatment free of charge. 129 00:07:39,179 --> 00:07:40,579 I will not allow it. 130 00:07:40,619 --> 00:07:43,819 Someone in your hospital is trying to kill Mr Okoye. 131 00:07:45,339 --> 00:07:48,379 Quite frankly, Dr Braithwaite, I don't need your permission. 132 00:08:01,139 --> 00:08:02,299 Haematology lab. 133 00:08:03,779 --> 00:08:05,739 Dr Braithwaite here. 134 00:08:05,779 --> 00:08:10,539 Wilfred Okoye, hospital number 1187266. 135 00:08:10,579 --> 00:08:13,019 I want all his stored blood and marrow samples sent 136 00:08:13,059 --> 00:08:14,699 to my office immediately. 137 00:08:41,859 --> 00:08:43,979 Finished! 138 00:08:44,019 --> 00:08:48,739 79 needles swabbed and ready to go. 139 00:08:50,299 --> 00:08:52,659 You've got to see this. 140 00:08:52,699 --> 00:08:54,659 Microbiology results from the syringe 141 00:08:54,699 --> 00:08:56,939 used in the attack on Wilfred. 142 00:08:56,979 --> 00:09:00,099 Turns out it is full of bacteria - E coli. 143 00:09:01,899 --> 00:09:04,059 Well, it was lying around on the floor. 144 00:09:04,099 --> 00:09:05,379 Could it be a contaminant? 145 00:09:05,419 --> 00:09:08,019 No. It's a pure growth - just one type of bug in there. 146 00:09:08,059 --> 00:09:09,899 If it was a contaminant you'd expect to see 147 00:09:09,939 --> 00:09:11,659 lots of different organisms. 148 00:09:11,699 --> 00:09:13,219 It's been created deliberately. 149 00:09:14,619 --> 00:09:18,299 So, what? The killer sneaks into Wilfred's room pretending 150 00:09:18,339 --> 00:09:21,859 to be a nurse, inoculates him with the bacteria, 151 00:09:21,899 --> 00:09:23,139 but adds a mild sedative... 152 00:09:25,419 --> 00:09:28,259 ..so that when the real nurse comes in with his medication, 153 00:09:28,299 --> 00:09:31,859 he's asleep and can't tell her that someone else has already been in. 154 00:09:33,059 --> 00:09:34,699 He gets sepsis, he dies. 155 00:09:34,739 --> 00:09:36,179 Looks like natural causes. 156 00:09:37,819 --> 00:09:39,579 I need to tell DI Cracknell. 157 00:09:39,619 --> 00:09:42,059 You need to tell the doctors looking after Wilfred. 158 00:09:46,379 --> 00:09:50,419 HEART MONITOR BEEPS 159 00:09:51,739 --> 00:09:53,899 HE BREATHES RAPIDLY 160 00:09:56,539 --> 00:09:59,139 ALARM SOUNDS 161 00:10:04,659 --> 00:10:06,499 HEART MONITOR BEEPS RAPIDLY 162 00:10:09,819 --> 00:10:11,939 HEART MONITOR FLATLINES 163 00:10:35,459 --> 00:10:38,339 It's as we expected - extensive peripheral oedema, 164 00:10:38,379 --> 00:10:41,619 multiple organ failure, consistent with sepsis. 165 00:10:41,659 --> 00:10:45,619 Yep. Toxicology shows only medications used for his treatment, 166 00:10:45,659 --> 00:10:49,099 antibiotics, ceftriaxone, gentamicin present 167 00:10:49,139 --> 00:10:50,859 in therapeutic concentrations. 168 00:10:50,899 --> 00:10:54,259 So, cause of death is consistent with deliberate inoculation 169 00:10:54,299 --> 00:10:57,139 of the culture of E coli, on a background 170 00:10:57,179 --> 00:11:00,499 of chemotherapy-induced immune compromise. 171 00:11:00,539 --> 00:11:03,739 Well, we've got no other leads on his attacker at present. 172 00:11:03,779 --> 00:11:05,939 We're liaising with the Beninese Consulate to inform 173 00:11:05,979 --> 00:11:08,579 the family of the deceased. 174 00:11:08,619 --> 00:11:13,939 DNA says Wilfred Okoye was guilty of Rahul's murder, 175 00:11:13,979 --> 00:11:16,339 but being unconscious, had the perfect alibi. 176 00:11:18,019 --> 00:11:20,939 When a murder suspect gets murdered, what does that mean? 177 00:11:20,979 --> 00:11:22,739 Framed by the real murderer? 178 00:11:22,779 --> 00:11:25,259 Why would you frame someone with the perfect alibi? 179 00:11:31,579 --> 00:11:33,779 Simi Jacobs. 180 00:11:33,819 --> 00:11:35,379 What's his home address? 181 00:11:35,419 --> 00:11:36,379 Erm... 182 00:11:38,299 --> 00:11:42,059 Let's see. Flat 32, Bardwell House, Lincoln Street. 183 00:11:42,099 --> 00:11:45,739 Thought so. Okoye and Jacobs have been living together. 184 00:11:45,779 --> 00:11:48,899 Simi Jacobs has already been released, guv. 185 00:11:48,939 --> 00:11:51,419 What? Yeah. Lack of forensics. 186 00:11:51,459 --> 00:11:52,979 All right. 187 00:11:53,019 --> 00:11:54,939 Might I suggest we pick him up again? 188 00:12:02,139 --> 00:12:04,259 It still doesn't get us anywhere. 189 00:12:04,299 --> 00:12:05,979 It doesn't explain the DNA. 190 00:12:06,019 --> 00:12:08,299 And Simi was in custody when Wilfred was attacked, 191 00:12:08,339 --> 00:12:09,699 so it doesn't even explain that. 192 00:12:09,739 --> 00:12:12,259 We're just going round in circles.Yep. 193 00:12:23,179 --> 00:12:26,259 When he was interviewed, Wilfred said his leukaemia 194 00:12:26,299 --> 00:12:29,019 was common in his region. 195 00:12:31,659 --> 00:12:32,939 Doesn't sound right to me. 196 00:12:47,979 --> 00:12:49,779 PHONE RINGS 197 00:12:49,819 --> 00:12:51,779 VOICEMAIL:You have reached Dr Adam Yuen. 198 00:12:51,819 --> 00:12:53,299 I am unable to take your call. 199 00:12:53,339 --> 00:12:55,219 Please leave a message after the tone. 200 00:12:58,139 --> 00:13:00,139 Wait there. He's not in, guv. 201 00:13:00,179 --> 00:13:01,899 And the neighbours haven't seen him. 202 00:13:01,939 --> 00:13:04,179 He's not been seen back at work at the hospital either. 203 00:13:04,219 --> 00:13:06,979 You two stick around in case he comes back. 204 00:13:07,019 --> 00:13:10,219 I'm sorry, guv. I should have spotted the address. 205 00:13:12,099 --> 00:13:14,019 Don't worry about it. 206 00:13:14,059 --> 00:13:17,179 At least you didn't wrongly arrest a bereaved cancer patient. 207 00:13:21,459 --> 00:13:23,019 I'll do that next time. 208 00:13:27,339 --> 00:13:28,339 Bye. 209 00:13:33,379 --> 00:13:35,499 Nine missed calls. You're very persistent. 210 00:13:38,579 --> 00:13:40,139 I didn't want to end it like that. 211 00:13:42,859 --> 00:13:44,459 Can I help? 212 00:13:55,619 --> 00:13:58,619 You should have told me that Emily Braithwaite is your godmother. 213 00:13:58,659 --> 00:14:00,419 Some godmother. 214 00:14:00,459 --> 00:14:03,059 No doubt you've received the incriminating evidence about me. 215 00:14:03,099 --> 00:14:04,299 What evidence? 216 00:14:05,939 --> 00:14:08,739 She never sent it. I should have guessed. 217 00:14:08,779 --> 00:14:11,779 If she tried to blackmail you, then we'll make her answer for that. 218 00:14:11,819 --> 00:14:12,939 She's far too clever. 219 00:14:14,939 --> 00:14:17,859 Why do I think there's more to this than you're telling me? 220 00:14:19,619 --> 00:14:21,779 No, I just lied to advance my career. 221 00:14:21,819 --> 00:14:24,779 Really? Just to say you had a fellowship. Why would you do that? 222 00:14:30,339 --> 00:14:31,939 My family are all doctors. 223 00:14:31,979 --> 00:14:33,939 I was always going to be a surgeon. 224 00:14:33,979 --> 00:14:35,539 It was more or less decided for me. 225 00:14:37,579 --> 00:14:40,659 Final year of medical school, I was walking to uni 226 00:14:40,699 --> 00:14:43,899 and a cyclist is knocked off her bike, right in front of me. 227 00:14:43,939 --> 00:14:45,699 Now, I was a keen student. 228 00:14:45,739 --> 00:14:48,819 I used to carry a first aid kit around with me. 229 00:14:48,859 --> 00:14:52,459 If I'm honest, I was always waiting for something like this. 230 00:14:52,499 --> 00:14:55,859 When I think about that it's actually what I'm most ashamed of. 231 00:14:55,899 --> 00:14:58,139 She had facial injuries. 232 00:14:58,179 --> 00:15:00,779 Heavy, laboured breathing. She was losing consciousness fast. 233 00:15:00,819 --> 00:15:02,779 So, I thought, "She's suffocating. 234 00:15:02,819 --> 00:15:07,059 "She needs a surgical airway, a cricothyroidotomy." 235 00:15:07,099 --> 00:15:08,499 So, I made my incision. 236 00:15:08,539 --> 00:15:10,979 Something that I had practised on mannequins. 237 00:15:11,019 --> 00:15:15,179 What I didn't know is that she had an abnormal anatomy - 238 00:15:15,219 --> 00:15:18,499 an aberrant subclavian artery, looping high in the neck. 239 00:15:19,739 --> 00:15:23,139 It's present in 1% of people and 0% of mannequins. 240 00:15:23,179 --> 00:15:25,459 How could you have known? It was a bloodbath. 241 00:15:33,099 --> 00:15:35,939 The artery retracted back into her chest. 242 00:15:35,979 --> 00:15:38,539 There was nothing we could do to save her. 243 00:15:38,579 --> 00:15:40,779 She bled to death in minutes. 244 00:15:45,179 --> 00:15:47,659 My father was furious. 245 00:15:49,379 --> 00:15:52,019 Not because I stupidly tried a tracheostomy 246 00:15:52,059 --> 00:15:53,819 and killed an innocent young girl. 247 00:15:55,459 --> 00:15:59,219 But because I didn't study hard enough to do it competently. 248 00:16:01,539 --> 00:16:05,939 So, he used his influence and arranged for my fellowship 249 00:16:05,979 --> 00:16:07,579 as cover. For what? 250 00:16:11,659 --> 00:16:13,059 For my absence. 251 00:16:16,539 --> 00:16:19,699 It took months of therapy before I could even leave the house. 252 00:16:28,579 --> 00:16:32,019 The irony in all of this is that the one who helped me out 253 00:16:32,059 --> 00:16:33,819 the most was Emily Braithwaite. 254 00:16:35,259 --> 00:16:37,779 She visited me more often than my parents. 255 00:16:40,779 --> 00:16:42,019 She understood. 256 00:16:45,019 --> 00:16:47,259 But there was no way I was going to be a surgeon. 257 00:16:51,059 --> 00:16:53,619 So, I decided to choose pathology, 258 00:16:53,659 --> 00:16:57,459 and a false narrative was created as to why I made the switch. 259 00:16:59,219 --> 00:17:02,019 When you start lying, 260 00:17:02,059 --> 00:17:04,339 you have to keep lying. 261 00:17:24,179 --> 00:17:26,179 Jack.Mm? I need to talk to you. 262 00:17:26,219 --> 00:17:27,539 Sure, what's up...? 263 00:17:30,099 --> 00:17:31,499 Hi. 264 00:17:31,539 --> 00:17:32,619 Are you kidding me? 265 00:17:36,019 --> 00:17:38,379 He doesn't work here any more because he lied to us, do you 266 00:17:38,419 --> 00:17:41,059 remember? Do you remember that? Adam's got a theory about Wilfred. 267 00:17:41,099 --> 00:17:42,659 Oh, right. Just hear him out. 268 00:17:42,699 --> 00:17:46,619 So, um, I just have to trust him now? 269 00:17:46,659 --> 00:17:48,539 No, you've got to trust me. 270 00:17:52,459 --> 00:17:53,619 Think about it. 271 00:17:54,859 --> 00:17:57,579 Why would someone want Wilfred dead? 272 00:17:57,619 --> 00:17:59,899 What did he know that was such a threat that someone 273 00:17:59,939 --> 00:18:00,899 had to kill him? 274 00:18:02,619 --> 00:18:06,019 Wilfred was being treated for acute myeloid leukaemia. 275 00:18:06,059 --> 00:18:07,219 That's rare. 276 00:18:07,259 --> 00:18:09,699 Remember, he said there were lots of other cases in his small 277 00:18:09,739 --> 00:18:11,899 village in Africa. 278 00:18:11,939 --> 00:18:14,699 What if Wilfred wasn't killed because of what he knew? 279 00:18:14,739 --> 00:18:15,739 Don't follow. 280 00:18:15,779 --> 00:18:17,579 Wilfred wasn't the witness. 281 00:18:19,859 --> 00:18:21,059 He was the evidence. 282 00:18:24,699 --> 00:18:26,939 This is a trephine biopsy of the bone marrow. 283 00:18:26,979 --> 00:18:30,779 We take a thin core of bone with marrow cells in it. 284 00:18:30,819 --> 00:18:33,059 I've already taken an aspirate of the fluids. 285 00:18:44,259 --> 00:18:47,699 So, the question is, why would so many people from one place 286 00:18:47,739 --> 00:18:49,099 all get leukaemia? 287 00:18:50,339 --> 00:18:52,259 And that's going to tell you, is it? 288 00:18:52,299 --> 00:18:53,979 To be honest, I've never done this before. 289 00:18:54,019 --> 00:18:56,059 Not postmortem, anyway. 290 00:18:56,099 --> 00:18:59,219 But you know what? It's crazy enough for it to work. Mm-mm. 291 00:19:11,019 --> 00:19:12,019 Thanks. 292 00:19:14,099 --> 00:19:17,419 Oh, look. Here's a billion DNA results from the needles. 293 00:19:19,099 --> 00:19:21,979 Want to give me a hand going through these? 294 00:19:22,019 --> 00:19:23,099 Didn't think so. 295 00:19:41,179 --> 00:19:43,779 Nikki? The slide's ready when you want to have a look. 296 00:19:52,259 --> 00:19:54,899 Good yield of cells. More than I expected. 297 00:19:54,939 --> 00:19:57,339 Definitely acute myeloid leukaemia. 298 00:19:57,379 --> 00:20:00,779 It's not typical. Looks more like secondary AML. 299 00:20:00,819 --> 00:20:03,499 Secondary to what? A toxin of some sort. 300 00:20:03,539 --> 00:20:05,619 Some industrial chemical, for example, 301 00:20:05,659 --> 00:20:09,499 or chemotherapy for a different cancer. 302 00:20:09,539 --> 00:20:12,379 Right. And that can occur years after the original exposure. 303 00:20:12,419 --> 00:20:14,419 Decades, in some cases. 304 00:20:14,459 --> 00:20:17,979 So, there may be other victims, all exposed to the same thing? 305 00:20:20,019 --> 00:20:21,379 Makes sense. 306 00:20:23,059 --> 00:20:27,099 BUZZING 307 00:20:40,219 --> 00:20:41,379 Can I help you? 308 00:20:41,419 --> 00:20:43,419 They told me Wilfred is here. 309 00:20:43,459 --> 00:20:45,259 Can I see him, yeah? 310 00:20:45,299 --> 00:20:47,539 Er, you are?Family. 311 00:20:49,779 --> 00:20:51,339 Do you want to take a seat? 312 00:20:51,379 --> 00:20:54,579 Will I be able to sit with him for a bit or...? I'll just check. 313 00:21:04,019 --> 00:21:06,419 I've found Rahul's murder weapon. 314 00:21:06,459 --> 00:21:10,019 One DNA profile matching Rahul, one matching Wilfred, 315 00:21:10,059 --> 00:21:11,899 just like we found at the scene. 316 00:21:11,939 --> 00:21:13,859 But there's a third profile. 317 00:21:15,659 --> 00:21:17,779 Yep. Simi Jacobs. 318 00:21:17,819 --> 00:21:19,819 Simi? He's here! 319 00:21:19,859 --> 00:21:22,619 What do you mean he's here? He wants to see Wilfred's body. 320 00:21:37,859 --> 00:21:40,539 This places Simi at the scene of Rahul's murder. 321 00:21:40,579 --> 00:21:42,539 We need to keep him here. 322 00:21:42,579 --> 00:21:44,139 Call DI Cracknell. 323 00:21:48,099 --> 00:21:50,619 So, hang on.Simi Jacobs just turned up at the lab. 324 00:21:50,659 --> 00:21:52,699 One needle injected into three people. 325 00:21:52,739 --> 00:21:54,099 Better get down here. 326 00:21:54,139 --> 00:21:56,179 Simi had a puncture wound to his neck. 327 00:21:56,219 --> 00:21:59,179 Rahul was stabbed in the chest, but Wilfred? 328 00:21:59,219 --> 00:22:00,939 And if Simi got in a fight with Rahul, 329 00:22:00,979 --> 00:22:02,899 why is Wilfred's blood spattered? 330 00:22:02,939 --> 00:22:05,499 Wilfred would have to have been in the room as well. 331 00:22:05,539 --> 00:22:07,539 Maybe he was. Genetically speaking. 332 00:22:08,979 --> 00:22:11,459 What if that needle only stabbed two people? 333 00:22:11,499 --> 00:22:14,259 Then one of them has two different types of DNA. Exactly. 334 00:22:14,299 --> 00:22:15,859 Huh? No, for that to work, it would 335 00:22:15,899 --> 00:22:18,539 mean Simi's walking around with Wilfred's blood inside him. 336 00:22:18,579 --> 00:22:20,419 That's ridiculous. Is it? 337 00:22:22,579 --> 00:22:25,659 Bone marrow transplant. And Wilfred was the donor. 338 00:22:25,699 --> 00:22:29,499 So, Simi's blood has Wilfred's DNA. 339 00:22:37,059 --> 00:22:38,819 Do you want to come this way?Yeah. 340 00:22:43,259 --> 00:22:44,299 Just there. 341 00:22:47,379 --> 00:22:50,139 Can I get you a tea? A glass of water or...? 342 00:22:50,179 --> 00:22:52,019 Oh, no, no! 343 00:22:52,059 --> 00:22:53,059 Thanks. 344 00:22:56,059 --> 00:22:58,339 You said that Wilfred was family? 345 00:22:58,379 --> 00:23:00,139 That's right. 346 00:23:00,179 --> 00:23:01,779 Was he a close relative? 347 00:23:03,419 --> 00:23:05,739 You ask a lot of questions. 348 00:23:05,779 --> 00:23:07,459 Remember me? 349 00:23:09,339 --> 00:23:11,299 I examined you at the station. 350 00:23:11,339 --> 00:23:12,659 I saw a scar on your chest. 351 00:23:12,699 --> 00:23:14,299 That's a Hickman line scar. 352 00:23:16,019 --> 00:23:18,219 Did you have a bone marrow transplant as a kid? 353 00:23:19,699 --> 00:23:21,459 Yeah, I'm going to go. 354 00:23:21,499 --> 00:23:24,299 Simi, we found your blood at the scene of Rahul's murder. 355 00:23:26,419 --> 00:23:27,539 Did you kill him? 356 00:23:30,459 --> 00:23:35,059 No, no, no. He... He came at me! He was insane! 357 00:23:35,099 --> 00:23:36,339 It was an accident! 358 00:23:40,579 --> 00:23:42,179 I just wanted to protect Wilfred. 359 00:23:44,499 --> 00:23:47,179 Wilfred saved my life when I was a kid. 360 00:23:47,219 --> 00:23:50,219 But you know what? He could only do that because he was a match. 361 00:23:50,259 --> 00:23:53,099 People have transplants from their brothers or mothers or whatever 362 00:23:53,139 --> 00:23:55,979 because they're a match. I had no-one. 363 00:23:57,459 --> 00:24:00,459 How did you find him? There's this charity attached to our church. 364 00:24:00,499 --> 00:24:02,499 They helped us get the transplant records. 365 00:24:04,539 --> 00:24:06,139 Only it turns out Wilfred was sick. 366 00:24:07,379 --> 00:24:09,579 Were there others? Yeah. 367 00:24:09,619 --> 00:24:12,659 I mean, loads of people in his village died from the same thing. 368 00:24:14,659 --> 00:24:16,259 We found Wilfred in time. 369 00:24:18,819 --> 00:24:20,259 So we thought. 370 00:24:22,219 --> 00:24:24,299 What? 371 00:24:24,339 --> 00:24:26,059 You're not going to let me see him? 372 00:24:30,179 --> 00:24:32,859 Simi. 373 00:24:32,899 --> 00:24:34,179 There he is. 374 00:24:54,699 --> 00:24:58,139 Ah, afternoon! Present from DI Cracknell - 375 00:24:58,179 --> 00:25:00,899 all the rubbish from Simi Jacobs' address. 376 00:25:00,939 --> 00:25:02,419 Thought you might want to take a look 377 00:25:02,459 --> 00:25:04,259 in case you find anything relevant. 378 00:25:04,299 --> 00:25:08,539 Joy. Can I introduce Reverend Kanu? You've already met Jack. 379 00:25:08,579 --> 00:25:12,619 This is Dr Nikki Alexander and Dr Adam Yuen. Hello. 380 00:25:12,659 --> 00:25:16,019 Reverend Kanu runs the charitable organisation that was responsible 381 00:25:16,059 --> 00:25:17,859 for bringing Wilfred to the UK. 382 00:25:17,899 --> 00:25:19,699 I have some photos from our trip. 383 00:25:19,739 --> 00:25:23,379 Sergeant Galloway thinks they might help you. Thank you. 384 00:25:23,419 --> 00:25:25,859 I have to warn you, they're not pretty. 385 00:25:29,099 --> 00:25:31,219 Tell me how Mr Okoye came to be here. 386 00:25:32,899 --> 00:25:37,139 My church runs a charity that helps arrange treatment in the UK. 387 00:25:37,179 --> 00:25:39,779 They raise money, get doctors to volunteer, whatever. 388 00:25:41,299 --> 00:25:43,699 Wilfred's case was kind of special. 389 00:25:43,739 --> 00:25:47,339 I mean, he helped me years ago, and now he needed my help. 390 00:25:47,379 --> 00:25:49,739 The local newspaper picked up the story, it got a lot 391 00:25:49,779 --> 00:25:53,019 of publicity. So, the hospital agreed to treat him. 392 00:25:53,059 --> 00:25:55,539 And he stayed at your flat? Yeah. 393 00:25:57,859 --> 00:26:00,659 Nobody told me he don't speak English. 394 00:26:00,699 --> 00:26:03,579 I couldn't tell him anything. 395 00:26:03,619 --> 00:26:06,819 He didn't know who I was, what he did for me. 396 00:26:09,139 --> 00:26:11,899 Then I learnt that he's under the care of this Rahul guy. 397 00:26:13,779 --> 00:26:18,579 I have travelled widely in Africa as part of my ministry, 398 00:26:18,619 --> 00:26:23,459 and yet nothing could have prepared me for what we found in Bwendora. 399 00:26:26,339 --> 00:26:29,579 The town is remote, even by African standards. 400 00:26:31,179 --> 00:26:34,419 There is only very basic health care. 401 00:26:34,459 --> 00:26:37,059 It became clear there was a lot of sickness. 402 00:26:38,939 --> 00:26:41,739 This man died within hours of our arrival. 403 00:26:43,019 --> 00:26:47,339 The illness causes bleeding and rashes. Fever sometimes. 404 00:26:47,379 --> 00:26:49,539 What do the people think it's caused by? 405 00:26:49,579 --> 00:26:52,619 There's a large pesticide factory in the town. 406 00:26:52,659 --> 00:26:55,739 Many people think the water has been contaminated. 407 00:26:55,779 --> 00:26:58,659 They organised protests. 408 00:26:58,699 --> 00:27:01,659 People think there has been a cover-up. 409 00:27:01,699 --> 00:27:04,099 But the factory provides a lot of employment. 410 00:27:05,459 --> 00:27:09,179 It is a very divisive issue. 411 00:27:09,219 --> 00:27:13,819 The illness has ripped the heart out of the community. 412 00:27:13,859 --> 00:27:16,899 There are very few families it has left untouched. 413 00:27:16,939 --> 00:27:18,899 And they've had no outside help? 414 00:27:18,939 --> 00:27:22,179 There is one western charity which runs a clinic, 415 00:27:22,219 --> 00:27:24,019 but they only visit every few months. 416 00:27:26,659 --> 00:27:27,859 Some charity. 417 00:27:30,779 --> 00:27:32,779 Oh, Lord. 418 00:27:32,819 --> 00:27:34,739 Enlighten our minds with your truth. 419 00:27:37,099 --> 00:27:40,139 Give us the strength and the wisdom to seek justice. 420 00:27:41,899 --> 00:27:45,739 Shine your everlasting light into our darkness. 421 00:27:48,059 --> 00:27:51,419 There's a lot of talk about Rahul, all around the hospital. 422 00:27:51,459 --> 00:27:53,939 How the hospital is protecting him. 423 00:27:53,979 --> 00:27:57,299 How he messed up an operation and no-one wants to work with him. 424 00:27:57,339 --> 00:28:00,099 And you thought he shouldn't operate on Wilfred. 425 00:28:00,139 --> 00:28:04,019 The night before, I heard him arguing with this woman, 426 00:28:04,059 --> 00:28:06,179 Dr Braithwaite. 427 00:28:06,219 --> 00:28:08,299 She told Rahul not to do the operation 428 00:28:08,339 --> 00:28:11,139 and he just told her that she couldn't stop him. 429 00:28:11,179 --> 00:28:13,579 The bag of rubbish that we found at your home address. 430 00:28:13,619 --> 00:28:15,619 Was it from one of the offices? 431 00:28:15,659 --> 00:28:17,019 Yeah. Which one? 432 00:28:18,099 --> 00:28:19,459 All of them. 433 00:28:19,499 --> 00:28:21,939 I was looking for something, anything, 434 00:28:21,979 --> 00:28:23,699 I could use against Rahul. 435 00:28:23,739 --> 00:28:26,299 And on the morning of the operation? 436 00:28:26,339 --> 00:28:29,219 I saw Wilfred getting prepared for theatre and I panicked. 437 00:28:29,259 --> 00:28:30,899 I phoned Rahul. 438 00:28:30,939 --> 00:28:32,499 What did you say? 439 00:28:32,539 --> 00:28:34,819 I told him I had some information on him. 440 00:28:34,859 --> 00:28:38,939 I thought I could threaten to reveal what I knew if he did the operation. 441 00:28:38,979 --> 00:28:40,179 What information? 442 00:28:42,699 --> 00:28:45,659 I was bluffing. But I had to stop him. 443 00:28:48,939 --> 00:28:50,699 Well, you certainly managed that. 444 00:29:05,899 --> 00:29:07,379 How's it going? 445 00:29:07,419 --> 00:29:10,699 Oh, I'm in my element rummaging through the trash. You know me. 446 00:29:11,899 --> 00:29:14,219 Nothing much here, apart from a criminally lax attitude 447 00:29:14,259 --> 00:29:15,179 to recycling. 448 00:29:17,419 --> 00:29:19,459 Adam's still here, is he? 449 00:29:19,499 --> 00:29:21,419 We wouldn't have got this far without him. 450 00:29:21,459 --> 00:29:23,019 I want to trust him. 451 00:29:25,539 --> 00:29:26,539 What's that? 452 00:29:31,619 --> 00:29:32,579 Oh, my God. 453 00:29:34,059 --> 00:29:38,659 This was in that rubbish bag you found at Simi Jacobs' place. 454 00:29:38,699 --> 00:29:41,699 It's Harry Fletcher's ECG, taken the day of his operation. 455 00:29:41,739 --> 00:29:43,139 It's normal. 456 00:29:43,179 --> 00:29:46,819 And this is the ECG that appeared in Fletcher's notes. 457 00:29:46,859 --> 00:29:50,059 Same date and time, but grossly abnormal. 458 00:29:50,099 --> 00:29:53,699 We believe they were switched to deflect blame from Rahul 459 00:29:53,739 --> 00:29:56,139 after the operation went wrong. 460 00:29:56,179 --> 00:29:58,139 So, there was a cover-up? 461 00:29:58,179 --> 00:30:00,819 Well, what's this got to do with the murder investigation? 462 00:30:00,859 --> 00:30:03,859 Yeah, Simi Jacobs admitted to the attack on Arnie Rahul. 463 00:30:03,899 --> 00:30:06,699 I mean, he claims it was an accident as a result of self-defence. 464 00:30:06,739 --> 00:30:08,339 That fits with the crime scene findings. 465 00:30:08,379 --> 00:30:10,739 So, how does this transplant fit in? 466 00:30:10,779 --> 00:30:13,579 Well, Simi was born with sickle cell disease, 467 00:30:13,619 --> 00:30:17,699 and was treated with a bone marrow transplant at St Jude's as a child. 468 00:30:17,739 --> 00:30:20,459 Wilfred donated his stem cells for Simi's transplant. 469 00:30:20,499 --> 00:30:22,739 20 years later, Wilfred gets leukaemia. 470 00:30:22,779 --> 00:30:24,739 We don't think this is a coincidence. 471 00:30:24,779 --> 00:30:27,939 He had a type of leukaemia that can be caused by over-exposure 472 00:30:27,979 --> 00:30:29,259 to certain drugs. 473 00:30:29,299 --> 00:30:32,619 There's a technique known as mobilisation, 474 00:30:32,659 --> 00:30:35,539 which is designed to increase production of stem cells. 475 00:30:35,579 --> 00:30:39,619 Normally, stem cell donation involves giving a perfectly safe 476 00:30:39,659 --> 00:30:41,219 bone marrow stimulant. 477 00:30:41,259 --> 00:30:46,139 But whoever did this also gave Wilfred high levels of chemotherapy, 478 00:30:46,179 --> 00:30:47,939 and did so repeatedly. 479 00:30:47,979 --> 00:30:50,299 They gave chemo? To a volunteer? 480 00:30:50,339 --> 00:30:52,459 To yield even more stem cells. 481 00:30:52,499 --> 00:30:54,739 What for? More transplants? 482 00:30:54,779 --> 00:30:59,699 Stem cells have the ability to develop into any type of body cell. 483 00:30:59,739 --> 00:31:01,659 Brain, heart, blood - you name it. 484 00:31:01,699 --> 00:31:03,939 So there's a huge range of potential therapies 485 00:31:03,979 --> 00:31:07,459 in which they can be used, one of which is transplantation. 486 00:31:07,499 --> 00:31:12,179 About ten years ago, Braithwaite and her team identified stem cells 487 00:31:12,219 --> 00:31:14,379 that were very special indeed, 488 00:31:14,419 --> 00:31:17,979 capable of being turned into what are called killer T-cells, 489 00:31:18,019 --> 00:31:22,019 part of the immune system, which can be made to attack malignant tumours. 490 00:31:22,059 --> 00:31:24,459 The potential for this discovery was enormous. 491 00:31:24,499 --> 00:31:26,739 These magic cells all had the same gene, 492 00:31:26,779 --> 00:31:30,979 a gene we think might be common in Wilfred's town. 493 00:31:31,019 --> 00:31:34,859 They went looking for transplant donors to treat people like Simi, 494 00:31:34,899 --> 00:31:37,579 but what they discovered was something much bigger, 495 00:31:37,619 --> 00:31:39,779 so they went back for more, and more. 496 00:31:39,819 --> 00:31:42,379 Basically they were flogging him for every last stem cell 497 00:31:42,419 --> 00:31:44,819 he could produce. Him and all the others. 498 00:31:44,859 --> 00:31:47,099 Wilfred's town was basically a stem cell farm. 499 00:31:47,139 --> 00:31:50,499 Can you prove Wilfred was given the stimulating drugs? 500 00:31:50,539 --> 00:31:53,739 It may be possible, but that's way out of my league. 501 00:31:55,459 --> 00:31:57,259 Sounds like we need a second opinion. 502 00:32:17,339 --> 00:32:18,659 Thank you, Professor. 503 00:32:18,699 --> 00:32:20,299 Not at all. It's very good to see you. 504 00:32:20,339 --> 00:32:21,779 Thank you. Oh, he's away! 505 00:32:23,659 --> 00:32:27,099 Adam, hello again. Hello. This is Dr Nikki Alexander. 506 00:32:27,139 --> 00:32:29,379 Hello.How do you do? And you've already met DI Cracknell. 507 00:32:29,419 --> 00:32:31,059 Yes, of course. This way. 508 00:32:32,019 --> 00:32:33,779 That was Alfie. 509 00:32:33,819 --> 00:32:37,859 He's one of our early trial patients - osteosarcoma. 510 00:32:37,899 --> 00:32:39,899 When he was referred to us, he was in a hospice 511 00:32:39,939 --> 00:32:43,499 on palliative treatment, expected to die within weeks. 512 00:32:43,539 --> 00:32:45,939 Please. That was two years ago. 513 00:32:47,299 --> 00:32:48,619 He's now disease-free. 514 00:32:51,459 --> 00:32:54,939 We wanted to show you some bone marrow samples from Mr Okoye. 515 00:32:54,979 --> 00:32:57,139 He was moved from St Jude's to be treated here. 516 00:33:05,699 --> 00:33:07,499 Hmm. 517 00:33:07,539 --> 00:33:09,139 Secondary leukaemia. 518 00:33:12,139 --> 00:33:13,619 They look very unusual. 519 00:33:13,659 --> 00:33:16,459 Mr Okoye was a stem cell donor. 520 00:33:16,499 --> 00:33:18,139 Was he? 521 00:33:18,179 --> 00:33:21,339 We were wondering if it might be stimulated. 522 00:33:21,379 --> 00:33:22,699 You mean Cyclo-G? 523 00:33:24,019 --> 00:33:25,579 Oh, dear. 524 00:33:25,619 --> 00:33:29,059 Yes, it's possible. 525 00:33:29,099 --> 00:33:32,059 Is there any way we can confirm it? 526 00:33:32,099 --> 00:33:34,859 You would need to look into the genetics of his blood cells. 527 00:33:34,899 --> 00:33:36,979 There are some telltale signs. 528 00:33:37,019 --> 00:33:40,379 We have several world experts in cytogenetics here. 529 00:33:40,419 --> 00:33:42,619 They'd be happy to help. 530 00:33:42,659 --> 00:33:45,619 Your cancer therapies are based on Braithwaite's stem cell research, 531 00:33:45,659 --> 00:33:49,779 are they not? Yes. Yes. I've never denied it. 532 00:33:49,819 --> 00:33:52,379 Hers was an extraordinary piece of work. 533 00:33:53,619 --> 00:33:56,659 She tried for years to turn it into a practical treatment, 534 00:33:56,699 --> 00:34:01,259 but, in the end, she was stumped by the obvious problem. 535 00:34:01,299 --> 00:34:03,139 The limited supply of donors. 536 00:34:03,179 --> 00:34:04,379 Precisely. 537 00:34:04,419 --> 00:34:08,819 So, what we brought to the party is called gene editing. 538 00:34:10,099 --> 00:34:13,699 We found a way of inserting the special gene 539 00:34:13,739 --> 00:34:16,059 into any old stem cell, and the result is... 540 00:34:17,219 --> 00:34:18,579 Well, you met Alfie. 541 00:34:19,819 --> 00:34:22,219 What is your relationship to Emily Braithwaite? 542 00:34:23,819 --> 00:34:25,379 Yes. 543 00:34:25,419 --> 00:34:28,539 Well, I suppose you'd say we're rivals. 544 00:34:28,579 --> 00:34:32,419 She's never forgiven me for succeeding where she failed. 545 00:34:32,459 --> 00:34:36,339 But I'm afraid her star has been waning for some time. 546 00:34:36,379 --> 00:34:37,699 What makes you say that? 547 00:34:40,099 --> 00:34:42,139 She came to ask for my help. 548 00:34:42,179 --> 00:34:45,779 Believe me, that alone suggests desperation. 549 00:34:45,819 --> 00:34:49,579 She had just lost a very large research grant. 550 00:34:49,619 --> 00:34:52,099 Is it possible that Braithwaite poisoned Mr Okoye 551 00:34:52,139 --> 00:34:55,379 and everyone else in his town to get more stem cells? 552 00:34:55,419 --> 00:34:58,179 That's a serious accusation. 553 00:34:58,219 --> 00:35:00,059 Everything's falling apart. 554 00:35:00,099 --> 00:35:02,459 So, like a gambler, she risks more and more, 555 00:35:02,499 --> 00:35:05,099 desperate for that big win to get herself back on top. 556 00:35:15,059 --> 00:35:20,539 THEY CONFER 557 00:35:23,819 --> 00:35:25,419 PHONE PINGS 558 00:36:00,619 --> 00:36:02,179 Now what? Excuse me? 559 00:36:03,419 --> 00:36:06,579 You do realise my career is over? And that's my fault? 560 00:36:06,619 --> 00:36:08,419 There's got to be a way out of this. 561 00:36:08,459 --> 00:36:09,699 You owe me that at least. 562 00:36:11,059 --> 00:36:13,659 You want Auntie Emily to make it better? 563 00:36:15,259 --> 00:36:19,339 All those years I stuck up for you with your father. 564 00:36:19,379 --> 00:36:22,299 You messed up. Again. 565 00:36:22,339 --> 00:36:24,139 For once in your life, own it. 566 00:36:26,379 --> 00:36:27,979 I don't get it. 567 00:36:28,019 --> 00:36:29,499 You and Rahul. 568 00:36:29,539 --> 00:36:31,619 You go to all these lengths to protect his reputation, 569 00:36:31,659 --> 00:36:34,459 yet you show no interest in who might have killed him. 570 00:36:34,499 --> 00:36:36,779 You don't even seem to even care that he's dead! 571 00:36:38,299 --> 00:36:40,779 Maybe I've learnt to bury my emotions. 572 00:36:42,659 --> 00:36:43,819 You should try it. 573 00:36:45,699 --> 00:36:47,899 You know they're onto you, 574 00:36:47,939 --> 00:36:50,539 and I'm not going to help you this time. 575 00:36:50,579 --> 00:36:51,739 Oh, please. 576 00:36:53,419 --> 00:36:54,779 This is so painful. 577 00:37:01,579 --> 00:37:04,059 So, all roads lead to Braithwaite. 578 00:37:04,099 --> 00:37:06,379 Yes, but it's all circumstantial. 579 00:37:06,419 --> 00:37:09,019 There's nothing directly connecting her to Wilfred. 580 00:37:09,059 --> 00:37:11,459 If you can find me something concrete, I'll bring her in, 581 00:37:11,499 --> 00:37:13,259 but until then, it's just speculation. 582 00:37:13,299 --> 00:37:15,699 Adam, where did you get to? 583 00:37:15,739 --> 00:37:18,299 Rahul's conduct during Fletcher's operation amounted to 584 00:37:18,339 --> 00:37:20,259 criminal negligence. 585 00:37:20,299 --> 00:37:22,219 He could have been charged for manslaughter. 586 00:37:22,259 --> 00:37:23,659 Well, he's dead. 587 00:37:23,699 --> 00:37:25,659 What if Braithwaite covered it up? 588 00:37:25,699 --> 00:37:28,099 That's attempting to pervert the course of justice. 589 00:37:28,139 --> 00:37:29,579 Which means you can arrest her. 590 00:37:29,619 --> 00:37:32,699 Oh, and how do we know that Braithwaite swaps the ECG? 591 00:37:32,739 --> 00:37:35,019 We can't. There are several sets of prints on the trace, 592 00:37:35,059 --> 00:37:36,619 one of which could be Braithwaite's. 593 00:37:36,659 --> 00:37:39,099 Exactly, so we can't just arrest her on the off-chance that 594 00:37:39,139 --> 00:37:40,499 her prints are on there. I know. 595 00:37:40,539 --> 00:37:41,939 ADAM:I met her for a drink. 596 00:37:45,979 --> 00:37:47,819 Her prints are on this glass. 597 00:37:47,859 --> 00:37:51,059 When you find that they are the same as the sets on the ECG, 598 00:37:51,099 --> 00:37:53,699 then you can arrest her. That's not admissible as evidence! 599 00:37:53,739 --> 00:37:55,339 It doesn't have to be. 600 00:37:57,019 --> 00:38:00,219 How do we know for sure she touched this glass? 601 00:38:00,259 --> 00:38:02,459 Well, you're just going to have to trust me. 602 00:38:49,179 --> 00:38:50,579 You two go round the back. 603 00:38:54,619 --> 00:38:56,019 DOORBELL RINGS 604 00:39:02,259 --> 00:39:04,299 Her car's here. Looks like she's home. 605 00:39:07,419 --> 00:39:08,459 No letterbox. 606 00:39:12,939 --> 00:39:14,299 Dr Braithwaite? 607 00:39:15,419 --> 00:39:17,579 DS Galloway. Could you open the door, please? 608 00:39:22,139 --> 00:39:24,099 Police! Dr Braithwaite? 609 00:39:36,219 --> 00:39:37,299 Shit. 610 00:39:43,659 --> 00:39:45,219 No sign of external injury. 611 00:39:47,099 --> 00:39:50,499 Both front and back doors were locked from the inside. 612 00:39:50,539 --> 00:39:53,139 There's no signs of forced entry. 613 00:39:53,179 --> 00:39:54,539 Everything's neat and tidy. 614 00:39:56,779 --> 00:39:58,059 Sudden chest pain, maybe? 615 00:39:59,699 --> 00:40:00,699 Or suicide. 616 00:40:33,219 --> 00:40:36,019 Nikki. Adam. Look at these. 617 00:40:41,539 --> 00:40:44,739 Two samples with Wilfred Okoye's name on. 618 00:41:07,739 --> 00:41:09,739 Look at this. 619 00:41:09,779 --> 00:41:11,979 The boiler's locked out. 620 00:41:12,019 --> 00:41:13,899 Yeah. Mine does that all the time. 621 00:41:13,939 --> 00:41:15,019 Bloody things. 622 00:41:53,579 --> 00:41:56,059 Heart weighs 380g. 623 00:42:22,259 --> 00:42:25,059 Evidence of left ventricular hypertrophy. 624 00:42:26,539 --> 00:42:27,939 Valves unremarkable. 625 00:42:31,259 --> 00:42:35,019 Left anterior descending coronary artery. 626 00:42:35,059 --> 00:42:38,099 Moderate stenosis, no evidence of thrombus. 627 00:42:46,579 --> 00:42:49,179 The toxicology was entirely negative, 628 00:42:49,219 --> 00:42:51,739 apart from a modest level of alcohol. 629 00:42:51,779 --> 00:42:55,779 No paracetamol, no benzodiazepines, nothing. 630 00:42:55,819 --> 00:42:59,339 So this, together with the absence of pills and containers 631 00:42:59,379 --> 00:43:02,259 at the address, and the absence of any needle marks on the body, 632 00:43:02,299 --> 00:43:05,419 leads me to conclude that death was not as a result 633 00:43:05,459 --> 00:43:08,019 of suicide or poisoning. 634 00:43:08,059 --> 00:43:11,419 In fact, the only significant finding from the postmortem 635 00:43:11,459 --> 00:43:14,459 examination is moderate ischaemic heart disease, 636 00:43:14,499 --> 00:43:17,859 together with hypertrophy of the septum and left ventricular wall. 637 00:43:17,899 --> 00:43:20,859 But no evidence of coronary thrombosis? 638 00:43:20,899 --> 00:43:23,819 The ventricular wall thickness... Heart attack. ..and the degree 639 00:43:23,859 --> 00:43:27,499 of myocardial disarray on microscopy are borderline 640 00:43:27,539 --> 00:43:29,699 for a diagnosis of HCM. 641 00:43:29,739 --> 00:43:32,539 What's that? Hypertrophic cardiomyopathy. 642 00:43:32,579 --> 00:43:35,939 It's an inherited heart condition that can lead to sudden death. 643 00:43:35,979 --> 00:43:37,819 Fabrice Muamba. Yes. 644 00:43:39,699 --> 00:43:43,419 Bolton Wanderers versus Tottenham. FA Cup quarterfinal, 2012. 645 00:43:43,459 --> 00:43:45,339 He collapsed on the pitch. Nearly died. 646 00:43:45,379 --> 00:43:47,219 Well, technically he did. 647 00:43:47,259 --> 00:43:49,339 In cases of high stress or exercise, 648 00:43:49,379 --> 00:43:53,459 the heart can lead into an abnormal rhythm, which can be fatal. 649 00:43:53,499 --> 00:43:56,259 And Emily Braithwaite was under a lot of stress. 650 00:43:56,299 --> 00:44:00,859 So it is possible that this caused a dysrhythmic event... 651 00:44:00,899 --> 00:44:03,619 Heart attack. ..that led to her death, don't you think? 652 00:44:07,739 --> 00:44:09,699 How come she didn't have a letterbox? 653 00:44:09,739 --> 00:44:11,939 It's a passive house. It's so well-insulated, 654 00:44:11,979 --> 00:44:14,579 it doesn't need heating. You heat it up just by living in it. 655 00:44:14,619 --> 00:44:16,419 But it has to be really airtight. 656 00:44:16,459 --> 00:44:18,579 It's like living in a bubble. 657 00:44:18,619 --> 00:44:21,699 All the air goes in and out through a single ventilation system. 658 00:44:23,339 --> 00:44:26,339 But why would the boiler lock out? 659 00:44:26,379 --> 00:44:30,739 What if it was faulty and produced a lot of carbon monoxide? 660 00:44:30,779 --> 00:44:33,059 No carbon monoxide in the toxicology. 661 00:44:37,419 --> 00:44:39,939 She's a suspect in a murder case. She conveniently dies. 662 00:44:39,979 --> 00:44:41,779 What if others were involved? 663 00:44:41,819 --> 00:44:43,979 If you can tell me how they did it, I'll believe you, 664 00:44:44,019 --> 00:44:47,499 but until then, it's looking like natural causes. 665 00:44:47,539 --> 00:44:51,099 Right, then, provisional assumption is that Braithwaite 666 00:44:51,139 --> 00:44:53,779 was guilty of conspiracy to murder Wilfred Okoye, 667 00:44:53,819 --> 00:44:56,659 as well as perverting the course of justice in the Fletcher case. 668 00:44:56,699 --> 00:44:57,899 What about Simi? 669 00:44:57,939 --> 00:45:01,899 That's up to the CPS, whether they buy a self-defence plea. 670 00:45:01,939 --> 00:45:03,459 I'll keep you posted. 671 00:45:21,459 --> 00:45:23,699 So this is where you've been hiding. 672 00:45:25,899 --> 00:45:27,739 Adam told you, then? 673 00:45:27,779 --> 00:45:30,299 Oh, yeah. He told me everything. 674 00:46:26,659 --> 00:46:28,059 I don't get it. 675 00:46:28,099 --> 00:46:31,059 How could someone like Braithwaite justify it to herself, 676 00:46:31,099 --> 00:46:32,419 let alone anyone else? 677 00:46:32,459 --> 00:46:34,899 They get fixated on the prize, don't they? 678 00:46:34,939 --> 00:46:38,459 The breakthrough, and all the acclaim that goes with it.Mm. 679 00:46:39,619 --> 00:46:42,699 Did you ever want to do something like that? Fancy research job? 680 00:46:43,779 --> 00:46:45,539 I think you'd be really good at that. 681 00:46:48,579 --> 00:46:49,539 I don't know. 682 00:46:50,659 --> 00:46:52,499 It's more Adam's world. Mm. 683 00:46:53,779 --> 00:46:54,859 Not any more. 684 00:46:56,619 --> 00:46:59,299 You can see how liberated he's been. 685 00:46:59,339 --> 00:47:02,499 He's carried that secret around for so long. 686 00:47:02,539 --> 00:47:05,979 Well, he's stopped trying to be all things to all men. 687 00:47:06,019 --> 00:47:08,859 And I'll tell you, he loves beating himself up. 688 00:48:08,419 --> 00:48:11,819 Hi. I'm working on the case of Wilfred Okoye. 689 00:48:11,859 --> 00:48:14,139 I was wondering if I could get his microbiology results 690 00:48:14,179 --> 00:48:15,579 from his stay here. 691 00:48:15,619 --> 00:48:18,059 Date of birth is 9/7/66. 692 00:48:23,459 --> 00:48:25,939 I just need to, er, speak to my supervisor. 693 00:48:25,979 --> 00:48:27,259 OK. Thank you. 694 00:49:05,099 --> 00:49:06,859 PHONE PINGS 695 00:49:06,899 --> 00:49:08,539 It's Adam. 696 00:49:10,779 --> 00:49:12,259 "We were wrong about everything. 697 00:49:14,459 --> 00:49:17,019 "At Cowley Institute. Come quickly." What? 698 00:49:20,419 --> 00:49:22,299 What are we looking at? 699 00:49:22,339 --> 00:49:25,099 Wilfred's blood cultures. Microbiology report. 700 00:49:28,019 --> 00:49:29,219 Hang on. 701 00:49:30,619 --> 00:49:34,219 The antibiotic sensitivities have been reversed. 702 00:49:34,259 --> 00:49:35,739 Who's done that? Braithwaite? 703 00:49:35,779 --> 00:49:38,299 Couldn't be. These are from the Cowley institute. 704 00:49:40,939 --> 00:49:42,579 Adam needs us. Come on. 705 00:50:12,139 --> 00:50:13,579 SHE SIGHS 706 00:50:13,619 --> 00:50:16,379 Oh, great. We were supposed to go left back at the lights. 707 00:50:30,619 --> 00:50:32,139 CAR DOOR OPENS 708 00:50:33,859 --> 00:50:34,859 Dr Yuen? 709 00:50:34,899 --> 00:50:38,099 You know Emily Braithwaite died yesterday? 710 00:50:38,139 --> 00:50:42,339 What? Uh, no. How did it happen? 711 00:50:42,379 --> 00:50:45,499 Unknown. Found dead in a house that was bolted from the inside. 712 00:50:47,059 --> 00:50:49,579 Oh, look, an oxygen analyser. 713 00:50:51,019 --> 00:50:52,819 Do you always keep one of those in your car? 714 00:50:52,859 --> 00:50:54,699 I use it for various things. 715 00:50:54,739 --> 00:50:57,979 So Emily died just as you convinced us she was guilty. 716 00:50:58,019 --> 00:51:00,739 Her work was based on exploitation. 717 00:51:00,779 --> 00:51:02,859 Well, she can't deny that now, can she? 718 00:51:02,899 --> 00:51:04,299 Well, whatever happened, 719 00:51:04,339 --> 00:51:07,539 I'm sure forensic science will find the answer. 720 00:51:07,579 --> 00:51:10,979 Mm. Then I realised just how much liquid nitrogen you go through here. 721 00:51:11,019 --> 00:51:13,019 Two deliveries in three days? 722 00:51:15,259 --> 00:51:18,579 I mean, that is some evil genius stuff. 723 00:51:18,619 --> 00:51:20,739 Pretty quick and very clean. 724 00:51:20,779 --> 00:51:24,259 Except the pilot light in the boiler went out at Braithwaite's house. 725 00:51:24,299 --> 00:51:25,699 Otherwise, the perfect crime. 726 00:51:26,939 --> 00:51:28,459 Are you insane? 727 00:51:28,499 --> 00:51:31,379 Oh, sorry. That's forensic science. Get out. 728 00:51:35,739 --> 00:51:38,379 Braithwaite had Wilfred's blood samples. She was onto you. 729 00:51:39,659 --> 00:51:41,459 My research is changing lives. 730 00:51:41,499 --> 00:51:43,099 She never made the crucial breakthrough, 731 00:51:43,139 --> 00:51:44,739 but then again, neither did you. 732 00:51:44,779 --> 00:51:46,899 You reckon you'll crack it any minute now, don't you? 733 00:51:46,939 --> 00:51:49,379 You just have to keep going, keep blasting innocent men 734 00:51:49,419 --> 00:51:51,859 and women with poisonous drugs, and then you'll get there. 735 00:51:51,899 --> 00:51:54,659 You know nothing. There's no gene editing going on here. 736 00:51:54,699 --> 00:51:57,059 Your magic treatments are all from stem cells that you get 737 00:51:57,099 --> 00:51:58,539 from killing people like Wilfred. 738 00:51:58,579 --> 00:52:02,179 When childhood cancer is a thing of the past thanks to me, 739 00:52:02,219 --> 00:52:04,419 no-one will care. 740 00:52:04,459 --> 00:52:07,019 That's what it's all about, isn't it? 741 00:52:07,059 --> 00:52:11,539 It's not about the money or the power. It's about the prestige. 742 00:52:13,219 --> 00:52:15,779 So what are you going to do about it, Adam? 743 00:52:15,819 --> 00:52:17,739 Mm? You're discredited. 744 00:52:17,779 --> 00:52:19,219 You're getting struck off. 745 00:52:20,499 --> 00:52:23,099 Of course I know! 746 00:52:23,139 --> 00:52:24,179 I know everything. 747 00:52:26,819 --> 00:52:29,179 You've no idea who you're dealing with. 748 00:52:31,699 --> 00:52:32,859 Adam? 749 00:52:35,179 --> 00:52:36,099 Adam! 750 00:52:38,579 --> 00:52:42,059 PHONE RINGS 751 00:52:42,099 --> 00:52:44,619 Adam? What's happening? 752 00:52:44,659 --> 00:52:48,059 Cowley's the one exploiting Wilfred and the rest of the donors. 753 00:52:48,099 --> 00:52:50,219 And he killed Braithwaite with liquid nitrogen. 754 00:52:50,259 --> 00:52:52,339 He poured it in the vent of her airtight house, 755 00:52:52,379 --> 00:52:55,819 turning it into a gas chamber. She suffocated. 756 00:52:55,859 --> 00:52:58,819 Cowley did a deal with Rahul to kill Wilfred during surgery. 757 00:52:58,859 --> 00:53:01,699 And when that failed, he attacked Wilfred with the bacteria... 758 00:53:04,099 --> 00:53:06,299 ..to make sure he switched the micro reports 759 00:53:06,339 --> 00:53:08,299 so that the antibiotics wouldn't work. 760 00:53:08,339 --> 00:53:10,219 ENGINE REVS 761 00:53:21,659 --> 00:53:22,819 Adam? 762 00:53:24,099 --> 00:53:25,299 Adam! 763 00:53:34,979 --> 00:53:36,419 HE COUGHS 764 00:53:44,979 --> 00:53:48,739 I'm sure that's Cowley. Really? Call Cracknell. 765 00:53:48,779 --> 00:53:50,859 But... Get after him. I'll find Adam. 766 00:53:59,499 --> 00:54:03,459 Yeah, I'm heading north on Colbridge Road. 767 00:54:03,499 --> 00:54:06,299 It's a black Mercedes. 768 00:54:06,339 --> 00:54:07,539 Adam? 769 00:54:07,579 --> 00:54:08,739 Adam! 770 00:54:08,779 --> 00:54:10,099 Oh, Jesus. 771 00:54:13,459 --> 00:54:15,019 Ambulance. 772 00:54:15,059 --> 00:54:18,219 SIRENS WAIL 773 00:54:21,139 --> 00:54:23,339 Can you hear me? Adam? 774 00:54:23,379 --> 00:54:25,819 You took your time, mate. 775 00:54:25,859 --> 00:54:27,179 Come to take all the credit? 776 00:54:29,059 --> 00:54:30,379 Oh, man. 777 00:54:31,939 --> 00:54:34,539 The ambulance is on its way. What happened? 778 00:54:34,579 --> 00:54:35,739 I messed up. 779 00:54:52,019 --> 00:54:53,019 You trusted me. 780 00:54:56,899 --> 00:54:57,899 That means a lot. 781 00:54:59,939 --> 00:55:02,459 Adam. Adam, stay with me. 782 00:55:02,499 --> 00:55:04,779 Adam. Come on, man. Stay with me. Stay with me. 783 00:55:04,819 --> 00:55:05,979 Come on! Adam! 784 00:55:07,259 --> 00:55:08,379 Adam! 785 00:55:26,579 --> 00:55:30,379 SIREN WAILS 786 00:55:55,419 --> 00:55:56,419 Oh, God. 787 00:56:03,539 --> 00:56:04,899 Oh, no. 788 00:56:09,499 --> 00:56:13,179 SHE SOBS 789 00:56:37,139 --> 00:56:43,459 # Testator silens 790 00:56:46,339 --> 00:56:53,059 # Costestes e spiritu 791 00:56:53,099 --> 00:56:59,579 # Silencium. # 88864

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