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These are the user uploaded subtitles that are being translated: 1 00:00:58,391 --> 00:01:02,157 What we are, in large part, depends on our genes. 2 00:01:02,295 --> 00:01:04,563 It is a hand we are dealt when we are born, 3 00:01:04,564 --> 00:01:07,727 and the cards we play our entire lives. 4 00:01:10,203 --> 00:01:12,538 You can study as hard you can, 5 00:01:12,539 --> 00:01:16,004 but some people will be smarter. 6 00:01:16,209 --> 00:01:19,838 Work out as much as you want. 7 00:01:21,381 --> 00:01:24,570 Some people are born to be bigger, 8 00:01:25,385 --> 00:01:28,687 or prettier, 9 00:01:28,688 --> 00:01:31,816 or more artistic. 10 00:01:36,262 --> 00:01:38,263 The hand you get depends upon the luck of the draw. 11 00:01:38,264 --> 00:01:39,998 Which genes you get from your mother, 12 00:01:39,999 --> 00:01:43,162 which you get from your father, 13 00:01:43,303 --> 00:01:46,464 and how they combine to make you a unique individual, 14 00:01:46,639 --> 00:01:47,906 is largely a matter of chance. 15 00:01:47,907 --> 00:01:49,775 In the game of life, 16 00:01:49,776 --> 00:01:52,904 the shuffling of genes to create 17 00:01:56,349 --> 00:01:58,417 a new individual is called sex. 18 00:01:58,418 --> 00:02:00,719 But life did not have to be this way. 19 00:02:00,720 --> 00:02:04,212 We could reproduce like some weeds do, 20 00:02:07,694 --> 00:02:09,628 by putting out shoots. Talk about a family tree! 21 00:02:09,629 --> 00:02:12,996 Or by fragmentation. 22 00:02:17,804 --> 00:02:20,339 A little gruesome, maybe, but it works for tapeworms. 23 00:02:20,340 --> 00:02:23,774 Spores are the method of choice for mushrooms. 24 00:02:26,513 --> 00:02:28,947 Millions could show up for a family reunion. 25 00:02:28,948 --> 00:02:32,041 Or we could do it the way amoebas do, 26 00:02:33,820 --> 00:02:36,321 simply getting fat, and dividing. 27 00:02:36,322 --> 00:02:39,450 But, no. We have to do it the hard way. 28 00:02:40,593 --> 00:02:43,495 For human reproduction, it takes two, and sex. 29 00:02:43,496 --> 00:02:45,664 This fact that it takes two organisms to produce one organism 30 00:02:45,665 --> 00:02:48,100 is really a paradox in biology, 31 00:02:48,101 --> 00:02:50,402 because it would be much simpler just for one organism 32 00:02:50,403 --> 00:02:52,804 to produce one organism... 33 00:02:52,805 --> 00:02:56,296 ...virgin birth, or to have females 34 00:03:04,184 --> 00:03:07,386 go about just cloning themselves and producing their offspring. 35 00:03:07,387 --> 00:03:12,654 Consider the whiptail lizard. 36 00:03:12,792 --> 00:03:17,229 These are parthenogenetic animals, which means they are all female. 37 00:03:17,363 --> 00:03:21,925 This individual will lay eggs and all of the offspring will be female, 38 00:03:23,836 --> 00:03:25,671 and they will be genetically identical to the sisters and to mom. 39 00:03:25,672 --> 00:03:27,406 Now, this is efficiency. 40 00:03:27,407 --> 00:03:31,571 A single sex. 41 00:03:31,711 --> 00:03:35,272 When a whiptail's biological clock goes off, she just lays some eggs. 42 00:03:35,415 --> 00:03:38,483 Sex education classes for whiptails would take about three minutes. 43 00:03:38,484 --> 00:03:41,486 No complicated mating or that sperm stuff, 44 00:03:41,487 --> 00:03:43,388 just instant motherhood. 45 00:03:43,389 --> 00:03:47,553 Life by default is female. 46 00:03:47,694 --> 00:03:49,328 Reproduction requires providing offspring with, with, ah, nourishments 47 00:03:49,329 --> 00:03:52,164 and, and resources and, 48 00:03:52,165 --> 00:03:55,965 and so, ah, this is the female function. 49 00:03:56,102 --> 00:03:58,203 Um, and asexual species, species that do not have sex, 50 00:03:58,204 --> 00:04:04,040 are always all female, um, with, without any males. 51 00:04:04,177 --> 00:04:09,274 And so the female function has to exist for life to exist. 52 00:04:10,583 --> 00:04:12,985 As you all know, for one thing and one thing only, do we need men! 53 00:04:12,986 --> 00:04:14,019 Can you not do any better than that? 54 00:04:14,020 --> 00:04:16,938 Oh! 55 00:04:16,939 --> 00:04:19,992 The way I like to think of it is that the female is the ancestral sex. 56 00:04:19,993 --> 00:04:23,053 In evolution the first individuals, 57 00:04:23,196 --> 00:04:25,097 replicating individuals, 58 00:04:25,098 --> 00:04:29,558 had to have been what we call a female-type of individual, 59 00:04:29,702 --> 00:04:34,503 and that males evolved after those kinds of individuals. 60 00:04:41,114 --> 00:04:45,312 But even here among the virgins, there is something else going on. 61 00:04:45,451 --> 00:04:48,353 They do not have any need or even equipment for mating, 62 00:04:48,354 --> 00:04:51,584 but that does not seem to stop them from trying. 63 00:04:52,558 --> 00:04:55,160 These individuals will interact in a way 64 00:04:55,161 --> 00:04:58,426 where one individual will take a male-like role. 65 00:04:58,564 --> 00:05:01,199 The other individual will take a female-like role. 66 00:05:01,200 --> 00:05:05,193 And in so doing, they will stimulate one another to lay eggs. 67 00:05:09,175 --> 00:05:11,810 But if males are not necessary for reproduction, 68 00:05:11,811 --> 00:05:13,345 why is there sex at all? 69 00:05:13,346 --> 00:05:16,780 Why did males evolve? 70 00:05:22,522 --> 00:05:25,958 The answers to why and how males became the second sex 71 00:05:26,092 --> 00:05:30,620 are coming out of research into microscopic single-celled organisms, 72 00:05:30,763 --> 00:05:32,931 bacteria. 73 00:05:32,932 --> 00:05:35,834 We can do things to the bacteria that we would never dream of 74 00:05:35,835 --> 00:05:38,170 doing to other organisms. 75 00:05:38,171 --> 00:05:40,105 We can manipulate their mates. 76 00:05:40,106 --> 00:05:43,872 We can make them have sex with members of different species even. 77 00:05:44,010 --> 00:05:47,045 We can do all kinds of terrible things to them 78 00:05:47,046 --> 00:05:50,641 and still come home at night and go to sleep without feeling bad. 79 00:05:52,352 --> 00:05:54,453 Although we do not think of bacteria as being sexual 80 00:05:54,454 --> 00:05:56,822 they do not have any of the obvious features that, 81 00:05:56,823 --> 00:05:59,191 that we look for in a sexy partner. 82 00:05:59,192 --> 00:06:03,128 They are in fact, very sexual creatures. 83 00:06:03,262 --> 00:06:05,731 Bacteria that I study, they do not have any hang-ups about mating, really. 84 00:06:05,732 --> 00:06:07,299 They take almost any DN A molecule. 85 00:06:07,300 --> 00:06:10,102 They bind it and they bring it into the cell. 86 00:06:10,103 --> 00:06:13,105 But they only recombine in those molecules that are from members 87 00:06:13,106 --> 00:06:16,301 of their same species. 88 00:06:16,342 --> 00:06:20,745 How sex started in the first place still puzzles evolutionary biologists. 89 00:06:20,880 --> 00:06:23,715 Perhaps it started with a cell eating an associate, 90 00:06:23,716 --> 00:06:26,218 the eater taking in the genes of the eatee. 91 00:06:26,219 --> 00:06:30,178 The complex and wonderful world of sexual creatures may have begun 92 00:06:30,323 --> 00:06:31,656 as cannibalism. 93 00:06:31,657 --> 00:06:33,892 Well, that is one idea. 94 00:06:33,893 --> 00:06:36,328 The second idea is that cells have sex, 95 00:06:36,329 --> 00:06:37,562 not for their own well-being, 96 00:06:37,563 --> 00:06:41,659 but because, for the transfer of the selfish, genetic elements that 97 00:06:41,801 --> 00:06:44,636 live inside the cell. 98 00:06:44,637 --> 00:06:46,538 This is the parasite theory. 99 00:06:46,539 --> 00:06:48,106 When you look at it this way... 100 00:06:48,107 --> 00:06:50,776 ...self-centered genes are in charge of evolution, 101 00:06:50,777 --> 00:06:54,645 and organisms are just a way for genes to duplicate themselves. 102 00:06:55,748 --> 00:06:59,741 The third view is that sex evolves a kind of repair shop, 103 00:06:59,886 --> 00:07:02,721 whereby the, the errors that are trapped in one cell 104 00:07:02,722 --> 00:07:06,954 can be repaired by the spare parts that exist in another cell. 105 00:07:07,093 --> 00:07:09,795 This is the view that we concentrated on in our work, 106 00:07:09,796 --> 00:07:13,196 and the view that we think makes the most sense. 107 00:07:16,169 --> 00:07:17,836 However sex got started, 108 00:07:17,837 --> 00:07:20,965 it seems safe to say that through eons of evolution, 109 00:07:21,107 --> 00:07:24,209 the creatures with two sexes were more successful than creatures 110 00:07:24,210 --> 00:07:26,378 with just a single sex. 111 00:07:26,379 --> 00:07:30,475 That is why sex has survived to become one of the facts of life. 112 00:07:41,461 --> 00:07:44,828 In the beginning, and for hundreds of millions of year, 113 00:07:44,964 --> 00:07:48,900 the earth's seas were seething with multiplying molecules. 114 00:07:49,035 --> 00:07:52,163 There was no sex and nothing much changed for eons, 115 00:07:52,305 --> 00:07:55,468 until one day some simple cells exchanged genes 116 00:07:55,608 --> 00:07:58,276 and changed the world, literally. 117 00:07:58,277 --> 00:08:02,270 Those simple cells that had sex, evolved. 118 00:08:05,184 --> 00:08:08,244 It began with the first species that covered the globe. 119 00:08:09,922 --> 00:08:11,189 Plants are basic. 120 00:08:11,190 --> 00:08:13,091 They are the food for all the world. 121 00:08:13,092 --> 00:08:18,655 And I consider biology the study of plants and their parasites. 122 00:08:18,798 --> 00:08:22,256 And everything else is a parasite on plants to eat them. 123 00:08:22,401 --> 00:08:23,735 We do. 124 00:08:23,736 --> 00:08:27,069 And if we do not eat the plants, we eat something that ate the plants. 125 00:08:27,840 --> 00:08:29,875 A botanist like Professor Warren Wagner 126 00:08:29,876 --> 00:08:32,744 can be forgiven for being a plant chauvinist. 127 00:08:32,745 --> 00:08:36,112 After all, in the beginning came pond scum. 128 00:08:36,549 --> 00:08:39,417 It starts with a green algae. 129 00:08:39,418 --> 00:08:43,218 And, the, the green algae have all sorts of life cycles. 130 00:08:43,356 --> 00:08:45,123 Then they, you get to the ferns, 131 00:08:45,124 --> 00:08:47,492 and the ferns have the simplest life cycle of all. 132 00:08:47,493 --> 00:08:49,094 They are quite decent. 133 00:08:49,095 --> 00:08:51,162 But then when you get to the sea plants, and particularly 134 00:08:51,163 --> 00:08:52,297 the flowering plants, 135 00:08:52,298 --> 00:08:53,999 it is really complicated, 136 00:08:54,000 --> 00:08:57,595 and you get many, many, many different forms of sexual reproduction. 137 00:08:58,804 --> 00:09:03,332 But what is the point? Why is there plant sex? 138 00:09:03,476 --> 00:09:06,578 The present thinking, I think, is that sex is necessary for 139 00:09:06,579 --> 00:09:08,780 the evolution of plants. 140 00:09:08,781 --> 00:09:10,916 Plants require two specialties. 141 00:09:10,917 --> 00:09:12,584 One of them is to reproduce, 142 00:09:12,585 --> 00:09:15,918 to reproduce themselves, to occupy space. 143 00:09:16,055 --> 00:09:18,123 And the other one is to change. 144 00:09:18,124 --> 00:09:19,024 You have got to change, 145 00:09:19,025 --> 00:09:20,792 because there are changes in climate... 146 00:09:20,793 --> 00:09:24,456 ...changes in rainfall, changes because of volcanoes, 147 00:09:24,597 --> 00:09:26,865 changes because of new kinds of organisms. 148 00:09:26,866 --> 00:09:31,166 And in order to be in this m�lange of all these constantly changing things, 149 00:09:31,304 --> 00:09:33,538 you are going to have to change yourself. 150 00:09:33,539 --> 00:09:36,701 And the only way to do that is through sex. 151 00:09:38,010 --> 00:09:41,104 But plants have roots. They can not move around much, 152 00:09:41,247 --> 00:09:43,548 so for there to be sex in the flower bed, 153 00:09:43,549 --> 00:09:47,645 plants had to find a go-between to exchange their genes. 154 00:10:12,945 --> 00:10:16,381 The secret to successful sex is attraction. 155 00:10:17,617 --> 00:10:19,384 Oh! Look, people. 156 00:10:19,385 --> 00:10:21,353 How do you like that marvelous plant? 157 00:10:21,354 --> 00:10:22,988 That is a Dutchman's pipe. 158 00:10:22,989 --> 00:10:24,089 Now let me tell you how this works. 159 00:10:24,090 --> 00:10:28,789 This is a classic example of plants that have weird pollination mechanisms. 160 00:10:28,928 --> 00:10:29,961 See the color? 161 00:10:29,962 --> 00:10:32,263 That chocolate color attracts flies. 162 00:10:32,264 --> 00:10:35,066 And the flies go there and say, "Good God! 163 00:10:35,067 --> 00:10:38,594 That wonderful thing there looks like something to eat. 164 00:10:38,738 --> 00:10:42,902 I could lay my eggs there and have baby grubs growing in it." 165 00:10:43,042 --> 00:10:45,910 So what they do is they go down inside. 166 00:10:45,911 --> 00:10:48,513 And in there are the sex organs. 167 00:10:48,514 --> 00:10:51,449 Now the only bad news is that they have hairs down here. 168 00:10:51,450 --> 00:10:54,285 These hairs are all pointing downward. 169 00:10:54,286 --> 00:10:55,420 And he can not get out. 170 00:10:55,421 --> 00:10:58,720 And he flies around madly in there and he gets all covered with pollen 171 00:10:58,858 --> 00:11:01,259 and then at a given moment, and only the flower knows 172 00:11:01,260 --> 00:11:04,199 when that is, the hairs all shrivel, 173 00:11:04,200 --> 00:11:07,206 and he flies up, all covered with pollen. 174 00:11:13,820 --> 00:11:16,541 The garden's glorious profusion, 175 00:11:16,542 --> 00:11:18,810 the shapes and fragrances of flowers, 176 00:11:18,811 --> 00:11:20,145 the intensity of color, 177 00:11:20,146 --> 00:11:22,981 exist to promote pollination. 178 00:11:22,982 --> 00:11:28,682 Blooming, buzzing, nature is pure unadulterated sex, and sexes. 179 00:11:33,592 --> 00:11:36,127 Botanists talk about male and female plants, 180 00:11:36,128 --> 00:11:38,963 but the difference between them lies primarily in the size and 181 00:11:38,964 --> 00:11:40,932 function of their sex cells, 182 00:11:40,933 --> 00:11:43,401 their gametes. 183 00:11:43,402 --> 00:11:47,668 We use the words males and females, not when we have ... just sex, 184 00:11:47,807 --> 00:11:52,301 but when we have sex between two gametes that are of different size. 185 00:11:52,445 --> 00:11:56,142 The female sex is the sex that produces a large, very expensive, 186 00:11:56,282 --> 00:11:58,450 and immobile egg. 187 00:11:58,451 --> 00:12:01,784 The male sex is the sex that produces the relatively cheap, 188 00:12:01,921 --> 00:12:05,118 small, and very mobile sperm cell. 189 00:12:05,257 --> 00:12:08,590 And so the basic male function as represented in the sperm cell 190 00:12:08,728 --> 00:12:11,629 is that of mobility of finding the egg. 191 00:12:11,630 --> 00:12:14,566 The basic female function as represented in the energy-rich egg, 192 00:12:14,567 --> 00:12:17,035 is that of nutrition. 193 00:12:17,036 --> 00:12:20,528 But the distinction between the sexes is not always clear, 194 00:12:20,673 --> 00:12:23,834 even among higher animals. 195 00:12:24,076 --> 00:12:27,045 Usually people think males are on one end of a continuum and 196 00:12:27,046 --> 00:12:28,880 females are on the other end. 197 00:12:28,881 --> 00:12:33,978 But in fact, we all begin as a bisexual organism 198 00:12:34,120 --> 00:12:40,491 and we then differentiate into male individuals or female individuals... 199 00:12:40,626 --> 00:12:43,261 ...in the case of mammals and many other vertebrates. 200 00:12:43,262 --> 00:12:47,892 What we have discovered over the last fifteen, twenty years is 201 00:12:48,033 --> 00:12:54,233 that the determination of sex is not a unitary phenomenon. 202 00:12:55,541 --> 00:12:59,944 Not a unitary phenomenon is a researcher's way of saying the 203 00:13:00,079 --> 00:13:03,446 whole thing is hugely complicated. 204 00:13:04,850 --> 00:13:08,080 It starts simply enough. 205 00:13:09,655 --> 00:13:14,456 All the genes in your body are packed into twenty-three pairs of chromosomes. 206 00:13:14,593 --> 00:13:17,857 One of the pairs controls gender. 207 00:13:21,333 --> 00:13:24,825 If the pair is two XX chromosomes, it is a girl. 208 00:13:24,970 --> 00:13:29,270 If one chromosome is an X and the other a Y, it is a boy. 209 00:13:30,009 --> 00:13:33,443 It is the luck of the draw. 210 00:13:33,879 --> 00:13:37,076 Except among some, like the leopard geckos, who seem determined to 211 00:13:37,216 --> 00:13:38,550 do things their own way. 212 00:13:38,551 --> 00:13:42,043 Sex chromosomes do not count, at least in the beginning. 213 00:13:42,621 --> 00:13:45,089 These are leopard geckos. 214 00:13:45,090 --> 00:13:49,026 The male is, as you can see, quite a bit larger than the female. 215 00:13:49,161 --> 00:13:52,063 They are unusual in that in these animals, 216 00:13:52,064 --> 00:13:56,000 the sex of the individual is not determined at fertilization 217 00:13:56,135 --> 00:13:58,269 or when egg and sperm meet. 218 00:13:58,270 --> 00:14:00,784 The sex is determined by the temperature 219 00:14:00,785 --> 00:14:03,798 at which the egg incubates. 220 00:14:04,877 --> 00:14:08,643 This gecko was incubated at ninety point five degrees Fahrenheit 221 00:14:08,781 --> 00:14:10,748 and became a male. 222 00:14:10,749 --> 00:14:14,845 This one was kept at seventy-eight point eight degrees Fahrenheit 223 00:14:14,987 --> 00:14:18,011 it and became a female. 224 00:14:35,474 --> 00:14:39,342 So they do have the genes for maleness and femaleness, 225 00:14:39,478 --> 00:14:41,246 just like in a human. 226 00:14:41,247 --> 00:14:45,411 But the temperature at which the egg incubates determines 227 00:14:45,551 --> 00:14:48,576 which cascade will be initiated. 228 00:14:50,122 --> 00:14:52,557 The cascade. Hormones. 229 00:14:52,558 --> 00:14:55,789 A complicated chain triggered by temperature in the gecko, 230 00:14:55,928 --> 00:14:58,363 by sex chromosomes in humans. 231 00:14:58,364 --> 00:15:01,822 Each hormone triggers a series of chemical reactions. 232 00:15:01,967 --> 00:15:05,403 The flood of chemicals, in carefully timed sequence, 233 00:15:05,537 --> 00:15:08,373 tell the body what to do. 234 00:15:08,374 --> 00:15:10,775 The result is masculine or feminine, 235 00:15:10,776 --> 00:15:14,006 depending on which hormone was acting when. 236 00:15:15,114 --> 00:15:20,074 That is true for hyacinths and Homo sapiens, for walruses and wrasse, 237 00:15:20,219 --> 00:15:23,517 which is a fish, a switch-hitting fish. 238 00:15:24,189 --> 00:15:29,320 In this tank we have two species of sequentially hermaphroditic fish. 239 00:15:29,461 --> 00:15:34,194 The white and black barred individuals are the humbug damselfish. 240 00:15:34,333 --> 00:15:38,201 The other individuals are the blue-head wrasse. 241 00:15:38,337 --> 00:15:43,604 In the blue-head wrasse you will have one male and a large number of females. 242 00:15:43,742 --> 00:15:46,577 And that male will dominate all of those females. 243 00:15:46,578 --> 00:15:49,247 If you remove that male, 244 00:15:49,248 --> 00:15:53,617 the largest female will, within minutes, begin to behave as a male, 245 00:15:53,752 --> 00:15:57,984 and within several weeks her physiology and morphology will change 246 00:15:58,123 --> 00:16:02,753 and she will become a male individual, whereas before she was female. 247 00:16:04,263 --> 00:16:07,699 What we think is happening in this process is that the brain 248 00:16:07,833 --> 00:16:10,961 is directing the sex change. 249 00:16:12,004 --> 00:16:15,122 In the humbug and the wrasse, behavior influences 250 00:16:15,223 --> 00:16:18,240 hormones, which in turn influence behavior. 251 00:16:18,377 --> 00:16:22,905 It happens in humans too, but in different ways. 252 00:16:23,048 --> 00:16:28,077 Even though the brain and thinking and psychology and the social influences 253 00:16:28,122 --> 00:16:33,114 are very important in human sexuality, 254 00:16:33,258 --> 00:16:38,423 we really have not overcome our hormonal ancestry. 255 00:16:38,564 --> 00:16:43,160 We still without a correct balance of estrogen and testosterone, 256 00:16:43,302 --> 00:16:46,204 neither males or females, men and women, 257 00:16:46,205 --> 00:16:47,972 can not function without that. 258 00:16:47,973 --> 00:16:52,137 And many, ah, of the clinical problems I see in my practice 259 00:16:52,277 --> 00:16:55,346 are due to hormone problems. 260 00:16:55,347 --> 00:16:58,483 There are dozens of hormones that have a variety of effects 261 00:16:58,484 --> 00:17:00,151 throughout a person's life. 262 00:17:00,152 --> 00:17:02,053 Adrenaline is a hormone. 263 00:17:02,054 --> 00:17:03,488 So is insulin, 264 00:17:03,489 --> 00:17:05,656 and so is testosterone, 265 00:17:05,657 --> 00:17:08,921 usually thought of as the male hormone. 266 00:17:09,728 --> 00:17:13,220 And estrogen, the female sex hormone. 267 00:17:14,633 --> 00:17:20,162 It is very easy for people to underestimate the power of hormones. 268 00:17:20,305 --> 00:17:25,572 It is very much like people underestimate radiation or electricity. 269 00:17:25,711 --> 00:17:32,116 You can not see it and the effective levels are so small 270 00:17:32,251 --> 00:17:35,743 that it might appear to be trivial. 271 00:17:35,888 --> 00:17:40,484 But these are extremely powerful compounds in the body, 272 00:17:40,626 --> 00:17:45,825 and they are what shape sex in the individual. 273 00:17:47,800 --> 00:17:51,258 It starts at conception. The genes trigger enzymes 274 00:17:51,403 --> 00:17:54,105 which produce testosterone and estrogen 275 00:17:54,106 --> 00:17:57,208 and control how the fetus develops. 276 00:17:57,209 --> 00:18:00,576 Scientists have learned a lot from times when the process, 277 00:18:00,712 --> 00:18:04,203 unfortunately, goes wrong. 278 00:18:05,384 --> 00:18:08,979 It has gone wrong for several families in the Dominican Republic. 279 00:18:09,121 --> 00:18:11,689 They are carriers of a rare genetic defect that 280 00:18:11,690 --> 00:18:15,592 affects the body's ability to recognize testosterone. 281 00:18:15,727 --> 00:18:18,696 Families like this one, which had seven daughters, 282 00:18:18,697 --> 00:18:21,722 gradually discovered they were mistaken. 283 00:18:23,469 --> 00:18:26,632 Chichi, when did you notice that you were not female? 284 00:18:28,640 --> 00:18:31,767 When I was about ten or twelve. 285 00:18:32,311 --> 00:18:35,540 And how did you notice it? 286 00:18:36,682 --> 00:18:39,707 Well, my breasts did not grow. 287 00:18:40,752 --> 00:18:42,353 Mario. What did you feel? 288 00:18:42,354 --> 00:18:45,022 How did you know that you were not a girl? 289 00:18:45,023 --> 00:18:48,083 In my muscles and in my body shape. 290 00:18:48,994 --> 00:18:52,088 This condition suppresses the male cascade. 291 00:18:52,231 --> 00:18:55,723 Baby boys have no visible penises or testes. 292 00:18:55,868 --> 00:18:59,031 Then, the surge of male hormones at puberty, 293 00:18:59,171 --> 00:19:02,470 testicles descend and the penis develops. 294 00:19:02,608 --> 00:19:06,169 Most of the boys successfully manage to make the gender switch then, 295 00:19:06,311 --> 00:19:09,643 and later marry as males. 296 00:19:12,885 --> 00:19:16,116 So, what you see is not always what you get with gender. 297 00:19:16,255 --> 00:19:19,918 Hormones must be produced and received in a specific order 298 00:19:20,058 --> 00:19:23,027 for everything to come out right. 299 00:19:23,028 --> 00:19:24,529 In the great majority of cases, 300 00:19:24,530 --> 00:19:27,231 it happens on schedule. 301 00:19:27,232 --> 00:19:29,600 Girls become women, 302 00:19:29,601 --> 00:19:32,403 and boys turn into men. 303 00:19:32,404 --> 00:19:36,932 Hormones serve as a biological clock through an individual's entire life, 304 00:19:37,075 --> 00:19:38,576 shaping our bodies, 305 00:19:38,577 --> 00:19:41,977 our lives, our society. 306 00:19:52,157 --> 00:19:55,854 We will now tell you the meaning of life. 307 00:19:55,994 --> 00:19:59,258 The meaning of life is making more life. 308 00:20:07,806 --> 00:20:11,139 The more researchers look at the behavior of living things, 309 00:20:11,276 --> 00:20:15,303 the more evidence they find that reproduction has choreographed 310 00:20:15,447 --> 00:20:18,505 the dance of life. 311 00:20:36,101 --> 00:20:40,697 The goal of both sexes is to have their genes represented 312 00:20:40,839 --> 00:20:42,740 in subsequent generations. 313 00:20:42,741 --> 00:20:46,700 The way in which males can most effectively do that is 314 00:20:46,845 --> 00:20:49,914 to inseminate a number of females. 315 00:20:49,915 --> 00:20:53,976 Now, from a female standpoint, one male is really enough, 316 00:20:54,119 --> 00:20:56,554 so long as he is a good male. 317 00:20:56,555 --> 00:20:59,990 Her major goal is to produce young that will 318 00:20:59,991 --> 00:21:03,426 live long enough to reproduce themselves. 319 00:21:05,597 --> 00:21:08,461 Nature's way of doing this is to hormonally 320 00:21:08,462 --> 00:21:11,469 activate certain behaviors in its creatures. 321 00:21:11,470 --> 00:21:16,567 An example: Some creatures have babies that are born pretty helpless. 322 00:21:16,708 --> 00:21:20,804 In the wild, a single parent cannot provide both food and constant 323 00:21:20,946 --> 00:21:22,413 care for its young, 324 00:21:22,414 --> 00:21:26,009 so nature invented pair bonding, couples. 325 00:21:28,587 --> 00:21:31,355 He likes to keep his hands in front of his face. He was even doing that in the... 326 00:21:31,356 --> 00:21:34,985 Infant dependency in humans may have lead to the common pattern 327 00:21:35,127 --> 00:21:37,561 that we see in humans of pair bonding. 328 00:21:37,562 --> 00:21:41,362 It may be that this put a very strong selective pressure on 329 00:21:41,500 --> 00:21:43,434 male parental involvement, 330 00:21:43,435 --> 00:21:46,836 which led to the formation of pair bonds in humans. 331 00:21:47,539 --> 00:21:49,807 To study how pair bonding happens, 332 00:21:49,808 --> 00:21:54,802 researchers have turned to a small, brown rodent, called the prairie vole. 333 00:21:54,946 --> 00:21:58,780 Early in our studies of the prairie vole we realized that 334 00:21:58,917 --> 00:21:59,984 when animals mated, 335 00:21:59,985 --> 00:22:02,453 their behavior changed very dramatically. 336 00:22:02,454 --> 00:22:06,049 If a female had mated with a male, she became, she began to prefer him. 337 00:22:06,191 --> 00:22:10,287 She, she seemed to become attached to him. 338 00:22:11,630 --> 00:22:14,690 Professor Sue Carter and her team at the University of Maryland looked 339 00:22:14,833 --> 00:22:17,635 at the hormone called oxytocin, 340 00:22:17,636 --> 00:22:19,403 which is produced during pregnancy, 341 00:22:19,404 --> 00:22:23,864 and known to promote mothering, as well as other behaviors. 342 00:22:24,009 --> 00:22:27,144 And very simply, when you give oxytocin to a female, 343 00:22:27,145 --> 00:22:30,247 it speeds up the rate at which she forms a social attachment 344 00:22:30,248 --> 00:22:33,476 for her partner. 345 00:22:33,885 --> 00:22:38,584 In male prairie voles, the changes after mating are also quite interesting. 346 00:22:38,724 --> 00:22:42,057 Before a male prairie vole mates, the males are very friendly. 347 00:22:42,194 --> 00:22:44,995 They are very non-aggressive, very good to each other. 348 00:22:44,996 --> 00:22:48,432 As soon as the male has mated, he becomes intensely aggressive, 349 00:22:48,567 --> 00:22:50,201 so aggressive that if he has to, he will kill a stranger in order to 350 00:22:50,202 --> 00:22:53,603 keep him out of his territory. 351 00:22:54,940 --> 00:22:56,374 Hormones again. 352 00:22:56,375 --> 00:23:00,436 Vasopressin was also found to be released in males during mating. 353 00:23:00,579 --> 00:23:05,346 This hormone has been shown to influence territorial behavior. 354 00:23:05,484 --> 00:23:08,319 So our evidence suggests that vasopressin 355 00:23:08,320 --> 00:23:12,484 plays a very important role in the onset of the aggressiveness 356 00:23:12,624 --> 00:23:15,718 or the mate-defensive component of monogamy. 357 00:23:16,995 --> 00:23:19,977 If some of the chemically controlled behavior of the prairie vole 358 00:23:19,978 --> 00:23:22,998 seems familiar, perhaps it is because human 359 00:23:22,999 --> 00:23:26,127 beings also produce oxytocin and vasopressin. 360 00:23:28,340 --> 00:23:31,901 The important question that many people would like to know the answer to is 361 00:23:32,043 --> 00:23:35,501 whether or not these hormones have the same behavioral effects in humans 362 00:23:35,647 --> 00:23:36,847 as they do in animals, 363 00:23:36,848 --> 00:23:40,248 and the answer unfortunately right now is, we do not know. 364 00:23:40,986 --> 00:23:43,287 Nature is conservative. 365 00:23:43,288 --> 00:23:47,156 It is a good guess if it has an effect on behavior in one species, 366 00:23:47,292 --> 00:23:50,590 it may have an effect in humans. 367 00:23:53,298 --> 00:23:55,964 In species like birds, where infants 368 00:23:55,965 --> 00:23:58,769 need a lot of care, pair bonding is common. 369 00:23:58,770 --> 00:24:01,898 Forty-five percent of bird species mate for life, 370 00:24:02,040 --> 00:24:05,874 and another forty-five percent stay faithful through the breeding season. 371 00:24:07,879 --> 00:24:10,347 Monogamy is rare among mammals. 372 00:24:10,348 --> 00:24:13,784 Only three percent take a single spouse for a lifetime. 373 00:24:13,919 --> 00:24:17,320 Human beings are an exception, more or less. 374 00:24:17,456 --> 00:24:20,584 Studies show a quarter of American married men and a fifth of American 375 00:24:20,725 --> 00:24:25,662 married women admit to having had adulterous affairs, 376 00:24:25,797 --> 00:24:31,463 and half the marriages in the US fail, by the fourth year on average. 377 00:24:31,603 --> 00:24:35,369 Perhaps we are not all programmed for lifetime bonding. 378 00:24:35,507 --> 00:24:38,772 In humans it is popular to talk about the seven-year itch, 379 00:24:38,910 --> 00:24:42,546 or now it is the, the four-year itch, suggesting that male interest 380 00:24:42,547 --> 00:24:46,183 in the pair bond wavers after some period of time. 381 00:24:46,318 --> 00:24:49,748 I do not know what the period of this is, but I think this really reflects a, 382 00:24:49,888 --> 00:24:53,051 a, probably a fundamental difference between males and females and the 383 00:24:53,191 --> 00:24:55,426 way they approach sexual behavior. 384 00:24:55,427 --> 00:24:59,193 I think it is the characteristic of males that the, they have been selected 385 00:24:59,331 --> 00:25:02,732 to be interested in sex on a relatively continuous basis. 386 00:25:02,868 --> 00:25:06,304 Females, on the other hand, have been selected to be interested in sex on 387 00:25:06,438 --> 00:25:07,972 an intermittent basis. 388 00:25:07,973 --> 00:25:10,074 When females are interested in sex, 389 00:25:10,075 --> 00:25:11,942 they are as intensely interested in sex as males are. 390 00:25:11,943 --> 00:25:14,812 It is just that it is not as frequent as the case for males. 391 00:25:14,813 --> 00:25:18,840 So I think this tendency for, ah, for pair bonds to split up 392 00:25:18,984 --> 00:25:19,917 after some period of time 393 00:25:19,918 --> 00:25:22,353 really reflect this tension between the male approach to sex and 394 00:25:22,354 --> 00:25:25,550 the female approach to sex. 395 00:25:31,530 --> 00:25:34,431 Gender differences in sexual desire have been stereotyped and 396 00:25:34,432 --> 00:25:36,967 perpetuated for millennia, 397 00:25:36,968 --> 00:25:39,770 but with even our gametes having different goals, 398 00:25:39,771 --> 00:25:43,240 perhaps there is more to this than meets the eye. 399 00:25:51,416 --> 00:25:54,977 Sexual behavior has been a focus of Professor Kim Wallen's work for 400 00:25:55,120 --> 00:25:58,247 over fifteen years. 401 00:25:58,290 --> 00:26:01,417 He studies rhesus monkeys. 402 00:26:03,528 --> 00:26:07,692 One of the striking characteristics of, ah, non-human primates is that... 403 00:26:07,832 --> 00:26:09,466 ...although they are capable of mating, 404 00:26:09,467 --> 00:26:12,169 most primate species are capable of mating at any time, 405 00:26:12,170 --> 00:26:15,264 actually hormones are very important when they do actually mate. 406 00:26:15,407 --> 00:26:17,207 So for a female rhesus, 407 00:26:17,208 --> 00:26:18,909 although she could mate at any time in her cycle, 408 00:26:18,910 --> 00:26:21,111 she actually only mates when she is fertile. 409 00:26:21,112 --> 00:26:25,071 This suggests to us that the hormones that the female's ovary produces 410 00:26:25,216 --> 00:26:28,549 actually influence her motivation to mate. 411 00:26:28,687 --> 00:26:31,455 In the twenty-eight day cycle of rhesus monkeys, 412 00:26:31,456 --> 00:26:34,789 Wallen has found that their sexual desire is greatest during their 413 00:26:34,926 --> 00:26:37,361 three-day period of fertility. 414 00:26:37,362 --> 00:26:39,863 During the days furthest from ovulation, 415 00:26:39,864 --> 00:26:43,356 no sexual interest or activity occurs. 416 00:26:44,369 --> 00:26:48,169 We find in humans like we find in other non-human primate species that 417 00:26:48,306 --> 00:26:52,242 the females interest in sex and her behavior varies across her cycle... 418 00:26:52,377 --> 00:26:55,412 ...and her interest in sex peaks at mid cycle at the time 419 00:26:55,413 --> 00:26:57,414 she would be ovulating. 420 00:26:57,415 --> 00:27:02,512 And hormones affect individuals, who then shape society. 421 00:27:02,654 --> 00:27:05,771 For example, work in our lab has recently found 422 00:27:05,772 --> 00:27:08,888 that for a male to be integrated into a rhesus group 423 00:27:09,027 --> 00:27:12,463 probably requires mating with one of the females in the group... 424 00:27:12,597 --> 00:27:17,261 ...and that this mating in public with one of the females 425 00:27:17,402 --> 00:27:21,270 is crucial for that male being accepted by the other females in the group. 426 00:27:21,406 --> 00:27:24,500 So sex serves not only a reproductive function, 427 00:27:24,643 --> 00:27:30,709 but it also serves the function of, ah, social cohesiveness and social integration. 428 00:27:41,226 --> 00:27:44,474 Once in a group, males may assume dominance 429 00:27:44,475 --> 00:27:47,723 by displacing others, especially around feeding sites. 430 00:27:49,668 --> 00:27:52,796 But the real social power is elsewhere. 431 00:27:54,305 --> 00:27:58,868 Males spend their life living in essentially a female-dominated social structure. 432 00:27:59,010 --> 00:28:01,645 And the females indicate when they want to engage in sex and 433 00:28:01,646 --> 00:28:05,509 who they want to engage with in sex, and they are very persistent about that. 434 00:28:14,559 --> 00:28:17,161 The pattern is common among other primate species, 435 00:28:17,162 --> 00:28:18,896 like these pig-tailed monkeys, 436 00:28:18,897 --> 00:28:22,355 and may have some analogs in human courting behavior. 437 00:28:33,978 --> 00:28:36,814 It is clear in monkey groups that the female regulates the sexual interaction 438 00:28:36,815 --> 00:28:40,307 and the female chooses which male she is going to mate with, 439 00:28:40,452 --> 00:28:42,252 and when she is going to mate. 440 00:28:42,253 --> 00:28:43,520 What is not clear is that 441 00:28:43,521 --> 00:28:47,389 she is selecting between individual males on the special characteristics 442 00:28:47,525 --> 00:28:49,793 that the males have. 443 00:28:49,794 --> 00:28:54,288 Maybe the only way to find out why one animal picks another is to ask. 444 00:28:54,999 --> 00:28:58,296 That is a boy gorilla. 445 00:28:59,270 --> 00:29:02,433 Ha, ha. Trouble? 446 00:29:02,574 --> 00:29:06,908 Coco was raised in captivity and taught to talk with sign language. 447 00:29:07,045 --> 00:29:12,377 When she reached sexual maturity, they created a video dating service for her. 448 00:29:12,517 --> 00:29:16,419 He lives alone, and he needs a girl. 449 00:29:16,554 --> 00:29:18,622 She knew what she did not like. 450 00:29:18,623 --> 00:29:21,854 She called one of her prospective suitors a toilet. 451 00:29:21,993 --> 00:29:26,328 She had her favorites, though did not explain what her criteria were. 452 00:29:32,003 --> 00:29:34,304 Do you like him? Good. 453 00:29:34,305 --> 00:29:37,207 But after two years of being with the male of her choice, 454 00:29:37,208 --> 00:29:41,144 Coco and Endume still have not consummated their relationship. 455 00:29:41,279 --> 00:29:45,045 And female choice remains as mysterious to scientists as 456 00:29:45,183 --> 00:29:48,208 it does to primate males. 457 00:29:54,292 --> 00:29:57,657 Nature is a sexy place. 458 00:29:58,830 --> 00:30:02,561 The living world is preoccupied with sex and mating. 459 00:30:07,472 --> 00:30:09,506 But for most plants and animals, 460 00:30:09,507 --> 00:30:12,635 sex is not without its costs and risks, 461 00:30:12,777 --> 00:30:15,974 to both individuals and species. 462 00:30:18,850 --> 00:30:21,652 Sex is a very expensive and time-consuming process. 463 00:30:21,653 --> 00:30:23,987 Humans are well aware of the effort involved. 464 00:30:23,988 --> 00:30:27,583 Most of us from birth, or early adolescence anyway, 465 00:30:27,725 --> 00:30:32,025 are preoccupied with finding a mate, keeping a mate, and so on. 466 00:30:32,163 --> 00:30:33,463 There is also the cost, 467 00:30:33,464 --> 00:30:35,632 I should say of infectious elements. 468 00:30:35,633 --> 00:30:39,194 Obviously, sex is a very intimate connection between the two organisms 469 00:30:39,337 --> 00:30:44,540 and so viruses and parasites that make their living by living inside other organisms in our bodies, 470 00:30:44,676 --> 00:30:47,077 for example, like the AIDS virus, and so on, 471 00:30:47,078 --> 00:30:52,414 they have seized upon the sexual act as an opportunity to transfer themselves. 472 00:30:54,352 --> 00:30:56,887 But there are other costs that are kind of hidden beneath the surface, 473 00:30:56,888 --> 00:31:00,851 which are actually more important from the point of view of the theory of evolution. 474 00:31:00,992 --> 00:31:02,526 These are the genetic costs; 475 00:31:02,527 --> 00:31:05,826 the fact that a female, by taking just one cell from her mate, 476 00:31:05,964 --> 00:31:06,864 the sperm cell, 477 00:31:06,865 --> 00:31:10,130 ends up reducing her genetic representation in her offspring 478 00:31:10,268 --> 00:31:12,035 by fifty percent. 479 00:31:12,036 --> 00:31:15,870 So that is a one-half dilution in her genes to the next generation. 480 00:31:16,007 --> 00:31:19,009 So this is a big genetic cost of sex. 481 00:31:19,010 --> 00:31:21,245 Then there are also just the costs of males, 482 00:31:21,246 --> 00:31:25,876 that is males take up roughly half the population in most species, 483 00:31:26,017 --> 00:31:27,918 but they do not produce anything. 484 00:31:27,919 --> 00:31:31,184 The rule in nature is that males do basically nothing. 485 00:31:32,757 --> 00:31:36,659 Life is full of males that consume much and contribute little. 486 00:31:36,794 --> 00:31:40,753 But their importance cannot be completely disregarded. 487 00:31:40,899 --> 00:31:45,836 It is important to think of males as being more than simply a repository of sperm. 488 00:31:45,970 --> 00:31:48,538 Males are more than a bag of sperm. 489 00:31:48,539 --> 00:31:51,975 The behavior of the male is absolutely essential for normal 490 00:31:52,110 --> 00:31:55,409 reproductive functioning of a female. 491 00:31:55,546 --> 00:32:00,950 So if females are housed with males that are not sexually active, 492 00:32:01,085 --> 00:32:06,489 those females will not go through the necessary physiological events 493 00:32:06,624 --> 00:32:10,526 that are required to produce offspring. 494 00:32:10,662 --> 00:32:12,696 Now in a sexual species, 495 00:32:12,697 --> 00:32:16,895 the male behavior is very important for the normal reproductive functioning 496 00:32:17,035 --> 00:32:19,970 of a female. 497 00:32:19,971 --> 00:32:26,570 Females that are isolated from males very, ah, rarely, ovulate. 498 00:32:26,711 --> 00:32:30,172 They need to see males. They need to be courted by males 499 00:32:30,315 --> 00:32:35,912 in order to show the normal neuroendocrine kinds of changes 500 00:32:36,054 --> 00:32:39,114 that are necessary to support reproduction. 501 00:32:44,862 --> 00:32:47,631 For human beings, the question is more complicated, 502 00:32:47,632 --> 00:32:50,701 partly because we cannot seem to shake the idea that men have 503 00:32:50,702 --> 00:32:52,836 always dominated society. 504 00:32:52,837 --> 00:32:56,739 But, it was probably Wilma, and not Fred, who was running things. 505 00:33:04,615 --> 00:33:08,415 I suspect that the sexual activity of early hominids was quite different 506 00:33:08,553 --> 00:33:10,187 than what we see in the modern society. 507 00:33:10,188 --> 00:33:13,256 First, females were probably sexually much more assertive 508 00:33:13,257 --> 00:33:14,591 than is the case today. 509 00:33:14,592 --> 00:33:18,790 And secondly, female social relations were probably much more crucial to 510 00:33:18,930 --> 00:33:21,431 the social structure of early hominid groups. 511 00:33:21,432 --> 00:33:24,731 I think that the characteristic pattern of males to be interested in 512 00:33:24,869 --> 00:33:28,498 sex rather continuously was probably the same then as it is today. 513 00:33:28,639 --> 00:33:31,733 But it was females that regulated the sexual activity by initiating sex 514 00:33:31,876 --> 00:33:34,811 with males when they were interested in it, 515 00:33:34,812 --> 00:33:37,973 and not engaging in sex when they were not. 516 00:33:54,399 --> 00:33:57,100 What has changed in humans is that they appear to be 517 00:33:57,101 --> 00:34:00,161 more specialized for sex than is the case in other primates, 518 00:34:00,304 --> 00:34:05,173 so that we have signals like breasts, lack of body hair with body hair 519 00:34:05,309 --> 00:34:09,336 accentuating the genitals and erogenous areas. 520 00:34:16,621 --> 00:34:20,182 But for humans, sex goes beyond simple pleasure. 521 00:34:22,160 --> 00:34:26,187 The importance of sex in people's lives really varies. 522 00:34:26,330 --> 00:34:29,424 Sex is very important, ah, in adolescence. 523 00:34:29,567 --> 00:34:32,335 Then if you find a nice partner and you are married, 524 00:34:32,336 --> 00:34:34,504 you do not think much about it then. 525 00:34:34,505 --> 00:34:36,306 Ah, then sex is like money. 526 00:34:36,307 --> 00:34:38,608 It, it becomes important if you do not have it. 527 00:34:38,609 --> 00:34:40,610 If you do not have a relationship, 528 00:34:40,611 --> 00:34:43,113 or if a person is not functioning well, 529 00:34:43,114 --> 00:34:45,615 then sex becomes extremely important 530 00:34:45,616 --> 00:34:47,284 and sort of takes over their whole lives 531 00:34:47,285 --> 00:34:49,686 and people cannot think of anything else. 532 00:34:49,687 --> 00:34:51,621 But when things go well... 533 00:34:51,622 --> 00:34:55,090 ...it is part of actual living. 534 00:34:58,496 --> 00:35:01,727 We are the only species which is always ready to have sex 535 00:35:01,866 --> 00:35:04,768 any season, any time of the month. 536 00:35:04,769 --> 00:35:08,000 And that has had some social consequences because rules and 537 00:35:08,139 --> 00:35:11,666 regulations and incest taboos had to be formed, 538 00:35:11,809 --> 00:35:15,074 otherwise we would be having sex with everyone all the time. 539 00:35:15,213 --> 00:35:18,881 So much of our social laws are for the control 540 00:35:18,882 --> 00:35:22,549 of the sex drive in its proper channels, 541 00:35:22,687 --> 00:35:26,087 otherwise society would be chaotic. 542 00:35:29,627 --> 00:35:32,562 Some societies have tried to keep that chaos at bay, 543 00:35:32,563 --> 00:35:36,055 by pretending sex was not a major force in our lives. 544 00:35:39,537 --> 00:35:43,701 There have been enormous advances in the last twenty-five years. 545 00:35:43,841 --> 00:35:48,676 Before that, the sexual, ah, the scientific study of sex was impossible 546 00:35:48,813 --> 00:35:50,380 and we were in the Dark Ages. 547 00:35:50,381 --> 00:35:55,080 As we go along, let us study the male anatomy. 548 00:35:55,219 --> 00:36:00,316 Most men know less about their own bodies than they do about their automobiles. 549 00:36:00,458 --> 00:36:04,394 Do not forget, masturbation was considered a diseases, 550 00:36:04,529 --> 00:36:08,381 and doctors and educators and psychologists would tie the kids' hands down, 551 00:36:08,382 --> 00:36:12,234 would tie the kids' hands down, ah, use electric shock and worse, 552 00:36:12,370 --> 00:36:16,232 to try to eradicate this disease. 553 00:36:46,704 --> 00:36:49,105 As late as 1959, 554 00:36:49,106 --> 00:36:52,371 half the seniors at five Pennsylvania medical schools 555 00:36:52,510 --> 00:36:55,775 believed masturbation would lead to insanity. 556 00:36:55,913 --> 00:36:59,940 One in five of their professors believed the same thing. 557 00:37:00,084 --> 00:37:04,350 And not one American medical college offered even a single course 558 00:37:04,488 --> 00:37:07,822 on human sexuality. 559 00:37:07,825 --> 00:37:10,293 We are totally in a different place. 560 00:37:10,294 --> 00:37:13,525 Today a person who cannot have erections, 561 00:37:13,664 --> 00:37:17,266 or trouble having feelings, sexual desire, can get help, 562 00:37:17,401 --> 00:37:20,402 because we know the hormones that are involved. 563 00:37:20,403 --> 00:37:23,903 We know the, the psychological factors that are involved. 564 00:37:26,143 --> 00:37:29,678 Perhaps the greatest surprise in recent research has been the influence 565 00:37:29,679 --> 00:37:33,213 that genes and chemistry have on all aspects of our behavior. 566 00:37:33,351 --> 00:37:37,253 The search is now on for biological factors in gender preference. 567 00:37:49,500 --> 00:37:53,168 Many homosexuals show some sadness and pain, 568 00:37:53,169 --> 00:37:56,836 or disturbance with their fathers and other males. 569 00:37:56,974 --> 00:38:00,307 But, on the other hand, there are also homosexuals who seem to have 570 00:38:00,444 --> 00:38:01,678 a perfectly normal development. 571 00:38:01,679 --> 00:38:05,615 So I think we are dealing with a multicausal phenomenon. 572 00:38:05,750 --> 00:38:09,242 Some people, their sexual preference is determined genetically. 573 00:38:09,387 --> 00:38:12,850 And in other cases, it may be just be preference or social choice, and, 574 00:38:12,890 --> 00:38:14,024 I do not know. 575 00:38:14,025 --> 00:38:17,051 And it is not a disease. So we do not look for a cause. 576 00:38:17,194 --> 00:38:20,857 But I think there are many conditions under which a person will grow up 577 00:38:20,998 --> 00:38:24,432 preferring their own, ah, gender. 578 00:38:25,269 --> 00:38:28,966 I think we have to accept that human sexuality varies widely. 579 00:38:38,482 --> 00:38:43,146 In the game of life, the odds are terrible... 580 00:38:43,287 --> 00:38:45,889 ...especially if you are a human sex cell. 581 00:38:45,890 --> 00:38:50,293 At best, your chances of becoming a person are one in millions. 582 00:38:51,996 --> 00:38:56,023 The human sperm, carrying half the genes necessary for a new life, 583 00:38:56,167 --> 00:39:00,297 must swim the equivalent of three miles, upstream. 584 00:39:00,438 --> 00:39:03,273 From a starting field of two hundred million sperm, 585 00:39:03,274 --> 00:39:06,766 only five hundred even get near the goal. 586 00:39:11,215 --> 00:39:15,083 Human eggs have a different battle, mainly old age. 587 00:39:15,219 --> 00:39:17,887 Unlike sperm which are made constantly, 588 00:39:17,888 --> 00:39:22,222 all the eggs a woman will ever have are formed when she is still in the womb. 589 00:39:23,661 --> 00:39:25,228 By the time she is born, 590 00:39:25,229 --> 00:39:29,030 her egg will already have dwindled from about twenty million to three million. 591 00:39:29,166 --> 00:39:33,260 By puberty, the gametes will have further reduced to perhaps 592 00:39:33,304 --> 00:39:35,939 three hundred thousand, 593 00:39:35,940 --> 00:39:39,899 and only three hundred will ever have the chance of being viable. 594 00:39:40,044 --> 00:39:43,512 Their chances decrease with age. 595 00:39:49,019 --> 00:39:52,145 Oh, let us see. 596 00:39:58,662 --> 00:40:02,147 To increase the odds, researchers have developed techniques 597 00:40:02,148 --> 00:40:05,632 that allow an egg to be fertilized outside the womb. 598 00:40:05,770 --> 00:40:07,737 Since 1978, 599 00:40:07,738 --> 00:40:11,765 thousands of children have been conceived in shallow glass dishes. 600 00:40:13,911 --> 00:40:16,813 Eggs can be artificially stimulated to develop, 601 00:40:16,814 --> 00:40:19,839 and then extracted for fertilization. 602 00:40:21,585 --> 00:40:25,053 Sperm are also subject to manipulation. 603 00:40:26,690 --> 00:40:29,359 Here we have a sample of sperm underneath a microscope 604 00:40:29,360 --> 00:40:31,194 that the TV camera is focusing on. 605 00:40:31,195 --> 00:40:33,563 We are evaluating the various patterns of motion. 606 00:40:33,564 --> 00:40:36,332 For instance we are looking at evidence of progressive motilla. 607 00:40:36,333 --> 00:40:39,427 We see this sperm moving progressively from the top to the bottom of the screen. 608 00:40:39,570 --> 00:40:42,539 And this would be a normal pattern of sperm motion. 609 00:40:42,540 --> 00:40:45,275 On the other hand, if we see sperm either being immobile 610 00:40:45,276 --> 00:40:47,777 or having a lot of difficulty in progressing, 611 00:40:47,778 --> 00:40:50,647 then all of these characteristics will affect their capacity 612 00:40:50,648 --> 00:40:53,774 to fertilize an egg. 613 00:40:53,984 --> 00:40:57,647 Even imperfect sperm can now play a part in reproduction. 614 00:40:57,788 --> 00:41:00,323 Using glass needles finer than a hair, 615 00:41:00,324 --> 00:41:03,589 sperm do not even have to be mobile to fertilize an egg. 616 00:41:03,727 --> 00:41:06,957 They can be directly injected through its wall. 617 00:41:08,466 --> 00:41:11,100 Right now, all of the advanced reproductive techniques 618 00:41:11,101 --> 00:41:13,436 are utilized in couples who are having difficulty in having healthy kids. 619 00:41:13,437 --> 00:41:19,535 For the most part it is, it is couples who are, ah, are having difficulty in conceiving. 620 00:41:19,677 --> 00:41:21,544 And in a more specialized area, 621 00:41:21,545 --> 00:41:26,107 there are those couples who have had, um, who are carriers of genetic disease 622 00:41:26,250 --> 00:41:29,879 in which we have the opportunity to, to, ah, to diagnose that 623 00:41:30,020 --> 00:41:31,955 genetic disease at the embryo level, 624 00:41:31,956 --> 00:41:34,491 and so that we can apply techniques 625 00:41:34,492 --> 00:41:37,360 to try to increase the chance of, of these, of these couples having 626 00:41:37,361 --> 00:41:39,095 a healthy infant. 627 00:41:39,096 --> 00:41:43,760 Reproductive technology has obviously answered dreams for some. 628 00:41:43,901 --> 00:41:46,903 Tens of thousands of children worldwide exist because of 629 00:41:46,904 --> 00:41:49,806 assisted conceptions. 630 00:41:49,807 --> 00:41:52,876 Among these children are some of the thirteen hundred 631 00:41:52,877 --> 00:41:54,277 who have been conceived with 632 00:41:54,278 --> 00:41:57,736 the help of the Jones Institute for Reproductive Medicine in Norfolk, 633 00:41:57,882 --> 00:42:01,144 Virginia. 634 00:42:03,320 --> 00:42:08,155 But does this mean we are approaching 635 00:42:08,292 --> 00:42:09,225 a brave, new world where babies are produced to order on a laboratory 636 00:42:09,226 --> 00:42:11,661 assembly line? 637 00:42:11,662 --> 00:42:14,464 I think that it is unlikely the use of advanced reproductive techniques 638 00:42:14,465 --> 00:42:17,567 themselves are going to, ah, change, ah, sexual behavior. 639 00:42:17,568 --> 00:42:21,664 Clearly, ah, this technique is not really a sexual process, 640 00:42:21,805 --> 00:42:23,540 ah, in that circumstance. 641 00:42:23,541 --> 00:42:26,738 Ah, I have sometimes gone out of the treatment room where we have 642 00:42:26,877 --> 00:42:29,112 done like an intrauterine insemination 643 00:42:29,113 --> 00:42:32,605 and asked, ah, and asked the husband if he wanted to smoke. 644 00:42:32,750 --> 00:42:35,451 But, ah, clearly that would be, ah, ah, 645 00:42:35,452 --> 00:42:38,321 I think that it is unlikely that this is going to put, ah, normal sexual 646 00:42:38,322 --> 00:42:41,553 behavior, ah, out of, ah, out of existence. 647 00:42:43,227 --> 00:42:47,596 Biotechnology is young, but its accomplishments are startling. 648 00:42:47,731 --> 00:42:52,498 We can freeze human sperm and embryos for future use. 649 00:42:52,636 --> 00:42:55,764 We can gestate a goat outside a womb. 650 00:42:57,708 --> 00:43:01,039 We can manipulate genes. 651 00:43:01,045 --> 00:43:03,279 The question arises whether or not in the future 652 00:43:03,280 --> 00:43:07,512 we will have the opportunity to try to utilize designer genes 653 00:43:07,651 --> 00:43:11,883 and push the evolution of our species toward a specific set of traits. 654 00:43:12,022 --> 00:43:14,924 Longevity, height, et cetera. 655 00:43:14,925 --> 00:43:17,627 I think that, ah, that possibility does exist. 656 00:43:17,628 --> 00:43:21,564 I think that it is probably, would be in the distal... in the distant, ah, future. 657 00:43:21,699 --> 00:43:24,300 It is cute. It works. I do not think it is really me. 658 00:43:24,301 --> 00:43:27,392 I agree. 659 00:43:29,139 --> 00:43:31,040 Like me. 660 00:43:31,041 --> 00:43:34,043 The future of sex has long been a preoccupation of science fiction 661 00:43:34,044 --> 00:43:35,845 writers and fans 662 00:43:35,846 --> 00:43:38,906 like these at Baltimore's Balticon Convention. 663 00:43:39,917 --> 00:43:42,185 Ah, however you like, that is fine. 664 00:43:42,186 --> 00:43:44,420 That is, that is actually pretty good. 665 00:43:44,421 --> 00:43:47,481 One, two three. Hold it! 666 00:43:47,625 --> 00:43:50,493 Don�t move! 667 00:43:50,494 --> 00:43:52,629 I think that probably there will be more people 668 00:43:52,630 --> 00:43:57,226 who are of indeterminate gender or ambiguous or several different genders. 669 00:43:57,368 --> 00:43:58,735 Actually I am a Borg. 670 00:43:58,736 --> 00:44:00,203 I am an asexual being 671 00:44:00,204 --> 00:44:04,766 that was assimilated into a, sort of a hive mentality, 672 00:44:04,908 --> 00:44:06,909 or a hive, a collective mentality. 673 00:44:06,910 --> 00:44:09,112 So, male and female do not matter. 674 00:44:09,113 --> 00:44:11,748 I suppose for folks that really want to have safe, 675 00:44:11,749 --> 00:44:14,217 safe sex more people by themselves, 676 00:44:14,218 --> 00:44:19,019 electronically, cyber, whatever, or, ah, virtual reality things are certainly, 677 00:44:19,156 --> 00:44:22,891 I do think those will be appropriate and not looked down upon in the future. 678 00:44:23,027 --> 00:44:26,162 Virtual sex is what most of us have when we do not have a partner. 679 00:44:26,163 --> 00:44:28,398 I think that sex is virtual all by itself. 680 00:44:28,399 --> 00:44:32,665 But, ah, given the, ah, given the current, ah, computer bulletin board and, 681 00:44:32,803 --> 00:44:34,470 ah, e-mail versions of sex, ah, 682 00:44:34,471 --> 00:44:36,806 I think that basically it is going to replace the vast majority of 683 00:44:36,807 --> 00:44:39,934 foreplay, at least for men. 684 00:44:39,943 --> 00:44:43,433 There you are. 685 00:44:45,649 --> 00:44:49,278 Today's attempts at moving sex into the interactive computer era 686 00:44:49,420 --> 00:44:54,824 are little more than animated comic books, explicit animated comic books. 687 00:45:00,898 --> 00:45:02,665 I have been expecting you. 688 00:45:02,666 --> 00:45:06,363 Shall we, mm, you know. 689 00:45:06,503 --> 00:45:10,030 I have been told that I have a very sexy body. 690 00:45:10,174 --> 00:45:13,009 Do you think I am sexy? 691 00:45:13,010 --> 00:45:16,444 Now, take off my tights. 692 00:45:18,549 --> 00:45:22,007 Oh. Does my body excite you? 693 00:45:22,152 --> 00:45:24,187 Tell the truth. 694 00:45:24,188 --> 00:45:26,856 But the industry promises Virtual Valerie 695 00:45:26,857 --> 00:45:29,726 is just the beginning of the new age of cybersex. 696 00:45:29,727 --> 00:45:32,819 Do you want to touch them? 697 00:45:33,497 --> 00:45:37,490 In here we can be anything we want to be. 698 00:45:37,634 --> 00:45:40,203 I will see you on the inside. 699 00:45:40,204 --> 00:45:43,332 It is predicted that the computer will project the images 700 00:45:43,474 --> 00:45:47,934 and provide the sensations for a kind of sex that can not exist in the real world. 701 00:45:48,078 --> 00:45:51,605 Ha, ha, ha, ha, ha., ha! Come over here. 702 00:45:51,749 --> 00:45:55,116 Virtual sex, which they are talking about today, is really not new. 703 00:45:55,252 --> 00:45:58,653 We all live in a virtual sex world. 704 00:45:58,789 --> 00:46:01,917 Whether, ah, we use a machine or our brains does not really matter. 705 00:46:02,059 --> 00:46:05,927 Our fantasies are virtual sexual reality. 706 00:46:10,434 --> 00:46:13,202 Maybe they will be enhanced a little bit by a machine, 707 00:46:13,203 --> 00:46:16,339 but you will still have to tell the machine what it is you like, 708 00:46:16,340 --> 00:46:18,574 what it is you desire, 709 00:46:18,575 --> 00:46:21,410 what, ah, what your fantasies really are. 710 00:46:21,411 --> 00:46:24,608 Perhaps the machines can make them a little bit more vivid, 711 00:46:24,748 --> 00:46:26,149 but I doubt it. 712 00:46:26,150 --> 00:46:29,677 I, our brains are the best virtual reality machines that there are. 713 00:46:31,588 --> 00:46:35,753 Throughout human history, our brains have been a primary sex organ. 714 00:46:38,629 --> 00:46:42,030 It is likely to continue that way into the future. 715 00:46:44,868 --> 00:46:46,736 I think that it will be, continue to be two sexes. 716 00:46:46,737 --> 00:46:49,401 But as we find extraterrestrial cultures, I am sure we will 717 00:46:49,402 --> 00:46:52,208 find a lot of variations that we have never even imagined yet. 718 00:46:52,209 --> 00:46:56,874 Actual change in the future by the, ah, freedoms of the female in the society. 719 00:46:57,014 --> 00:46:59,482 They will start taking more chances than the males, 720 00:46:59,483 --> 00:47:02,285 and more equality will arise. 721 00:47:02,286 --> 00:47:06,402 Ha, ha. I hope that sex and reproduction are all still tied into, like the 722 00:47:06,403 --> 00:47:10,519 making love, and that we do not lose too much of the old-fashioned ah... 723 00:47:14,431 --> 00:47:16,799 It seems unlikely. 724 00:47:16,800 --> 00:47:21,362 We are the product of our evolution, our genes and our hormones. 725 00:47:21,505 --> 00:47:24,440 But we are more than that. 726 00:47:24,441 --> 00:47:31,279 We are what we think, what we believe, what we imagine, what we hope. 727 00:47:31,415 --> 00:47:37,217 And that can transcend the selfishness of our genes, the fight for fertility, 728 00:47:37,354 --> 00:47:40,415 and the siren song of sex. 729 00:47:41,458 --> 00:47:45,495 One really crucial and unanswered question 730 00:47:45,496 --> 00:47:49,532 is whether species other than humans experience love. 731 00:47:49,666 --> 00:47:53,261 The power of love in humans is so striking that 732 00:47:53,403 --> 00:47:56,566 it seems unlikely that it is something that is unique to humans. 733 00:47:56,707 --> 00:47:59,642 On the other hand, there is no evidence 734 00:47:59,643 --> 00:48:04,340 in other non-human primates that anything analogous occurs. 735 00:48:05,849 --> 00:48:09,512 Love may be the answer to some questions science has not asked yet. 736 00:48:11,421 --> 00:48:14,447 Sex is easier to understand. 737 00:48:14,591 --> 00:48:17,754 For three billion years the game has been underway, 738 00:48:17,895 --> 00:48:22,457 shuffling physical characteristics and creating enough diversity 739 00:48:22,599 --> 00:48:26,063 to survive whatever hand Nature deals us. 740 00:48:29,606 --> 00:48:33,133 Sex is a game of change as much as a game of chance. 741 00:48:34,845 --> 00:48:38,281 Life is in the cards. 742 00:48:38,382 --> 00:48:43,382 www.freewebs.com/prijatel www.mkd-titlovi.niceboard.com 64808

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