Would you like to inspect the original subtitles? These are the user uploaded subtitles that are being translated:
1
00:00:02,000 --> 00:00:07,000
Downloaded from
YTS.MX
2
00:00:08,000 --> 00:00:13,000
Official YIFY movies site:
YTS.MX
3
00:00:16,570 --> 00:00:21,010
- In 2012, a team of British
researchers asked the question,
4
00:00:21,010 --> 00:00:23,430
what would happen if we treated
20 people suffering from
5
00:00:23,430 --> 00:00:25,763
severe depression with magic mushrooms?
6
00:00:31,980 --> 00:00:34,730
It took them three years to
get permission to find out.
7
00:00:38,910 --> 00:00:41,307
I've tried I think maybe
six or eight different
8
00:00:41,307 --> 00:00:43,207
antidepressants and have never worked.
9
00:00:46,335 --> 00:00:50,183
It I can't be for patients
has been four years ago,
10
00:00:51,320 --> 00:00:53,620
I realized that I couldn't go in on us.
11
00:00:53,620 --> 00:00:55,970
You know, she didn't say anything.
12
00:00:55,970 --> 00:00:57,140
Find a way to change
13
00:01:02,650 --> 00:01:06,000
About 50% of people don't
respond to antidepressants
14
00:01:06,000 --> 00:01:09,500
and one in six of them
go on to kill themselves.
15
00:01:09,500 --> 00:01:11,790
So we really should be exploring
16
00:01:11,790 --> 00:01:13,593
every other treatment available.
17
00:01:17,470 --> 00:01:20,340
With me, what I've always
been desperate to do is to try
18
00:01:20,340 --> 00:01:23,673
and find a physical reason
for feeling this way.
19
00:01:27,283 --> 00:01:30,500
Although I didn't want to take my life,
20
00:01:30,500 --> 00:01:31,333
I didn't want to wake up.
21
00:01:31,333 --> 00:01:34,743
I want to go to sleep, just
not have to face severe.
22
00:01:36,870 --> 00:01:40,123
Depression is so prevalent,
everyone's exposed to it.
23
00:01:41,550 --> 00:01:45,140
We're looking at giving
psilocybin to patients
24
00:01:45,140 --> 00:01:48,353
with quite severe treatment
resistant major depression.
25
00:01:51,090 --> 00:01:52,182
- I don't think it's
normal to feel the way
26
00:01:52,182 --> 00:01:55,380
I do the anxiety,
27
00:01:55,380 --> 00:01:58,610
the fear the terror panic. If this
28
00:02:01,330 --> 00:02:04,483
is living then it sucks. It really does.
29
00:02:28,852 --> 00:02:32,240
- LSD was isolated
by stolen Hoffman in a Sandoz
30
00:02:32,240 --> 00:02:34,490
pharmaceutical company
of Basel, Switzerland.
31
00:02:35,760 --> 00:02:38,010
The door swung wide open for research
32
00:02:38,010 --> 00:02:40,800
into the nature of this
piece of reading process,
33
00:02:40,800 --> 00:02:44,003
and in a larger sense into
the biochemistry of psychosis.
34
00:02:45,370 --> 00:02:49,870
between 1950 and 1965 40,000
patients were prescribed
35
00:02:49,870 --> 00:02:53,200
a psychedelic drug for
neuroses, schizophrenia
36
00:02:53,200 --> 00:02:54,203
and psychopathy.
37
00:02:55,310 --> 00:02:59,070
These trials resulted in
over 1000 scientific papers.
38
00:02:59,070 --> 00:03:00,050
If you have enough
39
00:03:03,930 --> 00:03:05,553
Is that a beautiful experience?
40
00:03:05,553 --> 00:03:10,250
I would say
41
00:03:13,130 --> 00:03:14,560
- when
psychedelics became available
42
00:03:14,560 --> 00:03:15,430
to the wider public
43
00:03:15,430 --> 00:03:19,353
in the 1960s, dramatic changes
in attitudes and behavior.
44
00:03:24,170 --> 00:03:27,670
- This is one area where
we cannot have budget cuts,
45
00:03:27,670 --> 00:03:31,100
because we must wage what
I have called Total War
46
00:03:31,100 --> 00:03:34,770
against public enemy number
one in the United States,
47
00:03:34,770 --> 00:03:37,020
the problem of dangerous drugs
48
00:03:37,020 --> 00:03:40,400
in 1971, under pressure
from President Nixon,
49
00:03:40,400 --> 00:03:42,930
the UN declared that all psychedelic drugs
50
00:03:42,930 --> 00:03:45,410
should be classified as schedule one.
51
00:03:45,410 --> 00:03:48,960
- One of the difficulties in
terms of schedule one drugs,
52
00:03:48,960 --> 00:03:51,190
including psilocybin, is that
53
00:03:51,190 --> 00:03:52,840
because they're in schedule one,
54
00:03:52,840 --> 00:03:55,440
this has discouraged any research
55
00:03:55,440 --> 00:03:58,090
into the middle medical value of that drug
56
00:03:58,090 --> 00:04:01,290
and there's been virtually
nothing in the world Research
57
00:04:01,290 --> 00:04:03,123
ever since 1960s.
58
00:04:04,220 --> 00:04:06,560
- With backing from
the Medical Research Council,
59
00:04:06,560 --> 00:04:09,090
the team at Imperial College
London are conducting
60
00:04:09,090 --> 00:04:11,970
the first ever clinical
trial of psilocybin,
61
00:04:11,970 --> 00:04:14,263
the active ingredient of magic mushrooms.
62
00:04:17,740 --> 00:04:20,620
- This isn't a job to rush if you think
63
00:04:20,620 --> 00:04:23,850
that somebody could have one of
64
00:04:23,850 --> 00:04:26,350
the most profound experiences
of their whole lives
65
00:04:29,296 --> 00:04:31,040
and they're ready for the music here.
66
00:05:03,880 --> 00:05:07,490
- That was taken was a winter of 2010
67
00:05:07,490 --> 00:05:10,540
when it was really cold
and we had a lot of snow
68
00:05:14,600 --> 00:05:16,250
so happy time.
69
00:05:16,250 --> 00:05:20,577
I was Yeah, yeah, it was
really nice. Yeah. I mean today
70
00:05:32,020 --> 00:05:33,750
going down to Imperial,
71
00:05:33,750 --> 00:05:36,520
it's actually Hammersmith hospital. And
72
00:05:38,220 --> 00:05:42,940
tomorrow is the first dosing day.
73
00:05:42,940 --> 00:05:45,190
Can you put into words
how important this is?
74
00:05:59,367 --> 00:06:00,200
But sir
75
00:06:01,620 --> 00:06:02,520
That's a tough one
76
00:06:24,744 --> 00:06:26,626
well we woke up Mikey got a call was it
77
00:06:26,626 --> 00:06:31,103
seems there was a fight so thank you
78
00:06:31,103 --> 00:06:32,770
for rolling resolving
that put my readers on.
79
00:06:32,770 --> 00:06:34,250
And because we're gonna sleep upstairs
80
00:06:34,250 --> 00:06:36,230
so we thought the price if
81
00:06:36,230 --> 00:06:38,230
we wait into the kitchen for some reason
82
00:06:40,220 --> 00:06:42,930
during the session there
was a tickle in the kitchen.
83
00:06:42,930 --> 00:06:45,012
We just thought oh well
it's just not much.
84
00:06:45,012 --> 00:06:47,150
We'll be we'll be fine.
85
00:06:47,150 --> 00:06:49,023
And the next thing we
knew that when we come
86
00:06:49,023 --> 00:06:50,340
back a few hours leading up
87
00:06:50,340 --> 00:06:52,850
to the step in there, how does
88
00:06:52,850 --> 00:06:56,570
that affect you in the knowledge
of the trial coming up,
89
00:06:56,570 --> 00:06:59,396
aim right at that point I thought
90
00:06:59,396 --> 00:07:01,096
I'm not going to do I can't do it.
91
00:07:02,140 --> 00:07:04,514
But for me, it's the last chance.
92
00:07:04,514 --> 00:07:05,668
I think this is that, you know,
93
00:07:05,668 --> 00:07:07,090
I don't think there's any all medicines
94
00:07:07,090 --> 00:07:09,600
that title these ones
that's been made in a lab
95
00:07:09,600 --> 00:07:13,110
and none of what, you know
the very short term impacts
96
00:07:13,110 --> 00:07:13,960
and then nothing.
97
00:07:32,330 --> 00:07:33,790
Over the past 30 years,
98
00:07:33,790 --> 00:07:37,653
I've had maybe 30 different
types of medication,
99
00:07:38,890 --> 00:07:43,030
antidepressants, some of them
have worked for a short time
100
00:07:43,030 --> 00:07:46,310
some work for a bit longer
but they all kind of tail off
101
00:07:49,550 --> 00:07:53,260
was I had a CT at 23
102
00:07:54,740 --> 00:07:59,740
sessions of which I've been
told worked for a period
103
00:08:00,160 --> 00:08:02,010
But then the effects you know, wore off.
104
00:08:02,010 --> 00:08:07,010
So I do feel like this trial
is another kind of last chance
105
00:08:07,640 --> 00:08:11,003
to make any kind of change for
me, but I felt that before.
106
00:08:17,130 --> 00:08:19,830
Robin Carhartt Harris is the trial lead
107
00:08:19,830 --> 00:08:22,830
and head of psychedelic
research at Imperial College.
108
00:08:22,830 --> 00:08:25,280
I have suffered from clinical depression.
109
00:08:25,280 --> 00:08:27,600
You know, I've been
through some dark times.
110
00:08:27,600 --> 00:08:31,860
So I think that kind of
thing helps you have sympathy
111
00:08:31,860 --> 00:08:36,163
for people who suffer from
New disorders in general.
112
00:08:38,910 --> 00:08:42,370
psychedelics are, for
me easily the best tool
113
00:08:42,370 --> 00:08:46,780
that exists to study both
the mind and the brain.
114
00:08:46,780 --> 00:08:50,830
I think it has the potential
to revolutionize depression
115
00:08:50,830 --> 00:08:53,773
treatment, if not psychiatry,
116
00:09:06,150 --> 00:09:10,170
Professor David Nutt, head
of neuro psychopharmacology
117
00:09:10,170 --> 00:09:12,270
will oversee the trial.
118
00:09:12,270 --> 00:09:14,560
This part of the brain
is called the cortex.
119
00:09:14,560 --> 00:09:18,540
And in the cortex, you do your
hearing and your seeing etc.
120
00:09:18,540 --> 00:09:20,210
but also in this part of the cortex,
121
00:09:20,210 --> 00:09:22,380
particularly this bit
here goes from the front
122
00:09:22,380 --> 00:09:24,140
to the back here.
123
00:09:24,140 --> 00:09:26,940
There's the sense of self.
124
00:09:26,940 --> 00:09:30,690
It integrates what you can see and hear
125
00:09:30,690 --> 00:09:33,760
and with what you can think and feel.
126
00:09:33,760 --> 00:09:36,130
And serotonin is an important
chemical in the brain.
127
00:09:36,130 --> 00:09:38,470
It's a fundamental neurotransmitter
128
00:09:38,470 --> 00:09:40,290
for regulating brain function,
129
00:09:40,290 --> 00:09:42,670
particularly in the emotional sphere.
130
00:09:42,670 --> 00:09:45,830
And what psilocybin and
other plant products do is
131
00:09:45,830 --> 00:09:47,470
to stimulate those receptors
132
00:09:47,470 --> 00:09:50,890
and by stimulating them we can
mimic serotonin in the brain,
133
00:09:50,890 --> 00:09:52,740
and sometimes perhaps,
134
00:09:52,740 --> 00:09:54,950
do more than serotonin is doing
135
00:09:54,950 --> 00:09:56,083
because in some people say returning
136
00:09:56,083 --> 00:09:57,713
may not be working adequately.
137
00:10:15,750 --> 00:10:17,255
As it will launch
138
00:10:17,255 --> 00:10:19,190
into more symbolic
139
00:10:20,924 --> 00:10:23,950
one life into another.
140
00:10:34,300 --> 00:10:38,414
Sometimes you think they be
strong because you don't want
141
00:10:38,414 --> 00:10:41,393
to come across as an emotional mess.
142
00:10:43,430 --> 00:10:46,380
I woke in the early
hours and I was weeping
143
00:10:47,620 --> 00:10:49,420
and I don't know where it came from.
144
00:10:51,260 --> 00:10:54,720
It's quite difficult.
It's it's quite tough
145
00:10:57,530 --> 00:11:00,260
their two days is the first time Simply
146
00:11:00,260 --> 00:11:02,870
to test the volunteers
tolerance to the drug.
147
00:11:02,870 --> 00:11:05,270
And the treatment days
will follow a week later.
148
00:11:06,630 --> 00:11:09,230
Each trip lasts about six hours.
149
00:11:09,230 --> 00:11:13,060
And a psychologist and
psychiatrist always in the room.
150
00:11:13,060 --> 00:11:15,000
The experience of taking
the capsules is going
151
00:11:15,000 --> 00:11:16,420
to be very significant for him.
152
00:11:16,420 --> 00:11:18,030
He's never experienced
anything like this at all
153
00:11:18,030 --> 00:11:19,470
in his life.
154
00:11:19,470 --> 00:11:20,380
And he's a scientist.
155
00:11:20,380 --> 00:11:24,100
He's someone that really enjoys
kind of the predictability
156
00:11:24,100 --> 00:11:27,810
of testing hypotheses and problems
157
00:11:27,810 --> 00:11:29,711
that can be solved without actually
158
00:11:29,711 --> 00:11:31,611
so this is a huge departure from that.
159
00:11:37,050 --> 00:11:39,390
I can remember being in the doctor's
160
00:11:39,390 --> 00:11:43,693
and feeling absolutely
ashamed of where i was.
161
00:11:45,780 --> 00:11:50,510
You know, I worked as a
scientist and as a team leader,
162
00:11:50,510 --> 00:11:51,890
and out of the blue,
163
00:11:51,890 --> 00:11:56,370
I was told that I had to work
in a procurement department
164
00:11:57,390 --> 00:12:00,850
and this was pretty much
my vision of how Really,
165
00:12:00,850 --> 00:12:03,883
there was just this a base
that was in front of me.
166
00:12:04,741 --> 00:12:09,430
And I went to see the
occupational health nurse.
167
00:12:09,430 --> 00:12:11,950
Before I knew it was in floods of tears
168
00:12:11,950 --> 00:12:13,923
and just completely burned down.
169
00:12:14,870 --> 00:12:19,220
And she said to me, there's
something seriously wrong me.
170
00:12:19,220 --> 00:12:23,763
And yeah, we're, what, 13
years down the road now.
171
00:12:37,850 --> 00:12:38,900
Real laughs a minute.
172
00:12:44,420 --> 00:12:46,840
I have been thinking about it
quite a lot this afternoon.
173
00:12:46,840 --> 00:12:50,700
I'm worried that he's so different,
174
00:12:50,700 --> 00:12:52,860
that I take a long time to catch up,
175
00:12:52,860 --> 00:12:54,433
and he loses patience with me.
176
00:12:56,420 --> 00:12:59,100
So yeah, I'm a bit concerned.
177
00:12:59,100 --> 00:13:00,893
I'm going to get left behind. Oh oh
178
00:14:01,550 --> 00:14:04,000
Very powerful, very powerful going.
179
00:14:04,000 --> 00:14:07,650
And that was that was
two capsules next week.
180
00:14:07,650 --> 00:14:09,540
So five capsules
181
00:14:10,460 --> 00:14:12,970
What are your thoughts
about next Wednesday?
182
00:14:12,970 --> 00:14:17,970
They're probably more anxious,
actually, if I'm honest,
183
00:14:18,250 --> 00:14:21,100
because of what came up
today.and that I know
184
00:14:21,100 --> 00:14:24,770
that could get amplified next Wednesday.
185
00:14:24,770 --> 00:14:28,053
So I think there's a battle
there that's not done yet.
186
00:14:29,930 --> 00:14:32,900
- He was taken back to a
very, very difficult memory
187
00:14:32,900 --> 00:14:34,243
which he didn't think was a memory.
188
00:14:34,243 --> 00:14:36,800
It was kind of a new experience
that he was going through
189
00:14:36,800 --> 00:14:37,907
of having his mother on the one side
190
00:14:37,907 --> 00:14:41,320
and his father on the other
having to choose between them.
191
00:14:41,320 --> 00:14:44,530
And he went to be with the
very calm, benevolent energy
192
00:14:44,530 --> 00:14:47,833
of his dad, and he felt the
presence of this dad there.
193
00:14:47,833 --> 00:14:50,520
He said he actually really
kind of met his dad again
194
00:14:50,520 --> 00:14:52,520
and felt his dad wrapped around him.
195
00:14:52,520 --> 00:14:56,740
He could feel the knit of the
cardigan his dad used to wear.
196
00:14:56,740 --> 00:14:58,400
So that was a really difficult
197
00:14:58,400 --> 00:15:02,043
but also very positive
powerful experiences.
198
00:15:25,620 --> 00:15:28,180
- It's a huge
responsibility for you, this.
199
00:15:28,180 --> 00:15:30,940
Do you get sort of scared or nervous?
200
00:15:30,940 --> 00:15:35,940
- I do, I think if you're
giving a incredibly powerful
201
00:15:36,120 --> 00:15:38,960
psychoactive drug to individuals
202
00:15:38,960 --> 00:15:42,320
who are especially vulnerable,
203
00:15:42,320 --> 00:15:45,930
you have to think about negative
psychological responses.
204
00:15:45,930 --> 00:15:48,450
You have to think about anxiety.
205
00:15:48,450 --> 00:15:52,965
You have to think about
fear and potential panic.
206
00:15:56,484 --> 00:15:58,473
- Let's just carry
on breathing naturally.
207
00:16:01,410 --> 00:16:03,010
And then I'd like you to imagine
208
00:16:04,426 --> 00:16:06,953
that you're lying down
in a beautiful woodland.
209
00:16:12,040 --> 00:16:13,103
You're in a clearing,
210
00:16:16,592 --> 00:16:19,950
and the ground is covered with
green most, soft and springy.
211
00:16:22,330 --> 00:16:24,510
- I think depression's
about like an addict.
212
00:16:24,510 --> 00:16:26,713
You learn to hide it from people.
213
00:16:26,713 --> 00:16:28,620
people in arms.
214
00:16:28,620 --> 00:16:29,570
I don't want no sympathy.
215
00:16:29,570 --> 00:16:32,046
I don't even want a lot of kindness.
216
00:16:32,046 --> 00:16:33,100
And I would like to go into the bedroom
217
00:16:33,100 --> 00:16:36,050
and close the curtains, put
the lights off, and just stare.
218
00:16:41,720 --> 00:16:46,110
- It's a big day, probably as
big a day as our wedding day
219
00:16:46,110 --> 00:16:48,106
maybe 'cause this could be the start
220
00:16:48,106 --> 00:16:50,689
of a new life, fingers crossed.
221
00:17:06,980 --> 00:17:08,950
- In mental health, you just have to go
222
00:17:08,950 --> 00:17:13,660
into an inpatient ward
anywhere and realize
223
00:17:13,660 --> 00:17:15,950
that we need something new.
224
00:17:15,950 --> 00:17:17,223
So John and the other
patients in the trial
225
00:17:17,223 --> 00:17:20,320
have got what's called
treatment-resistant depression,
226
00:17:20,320 --> 00:17:22,750
which means they've tried
three different types
227
00:17:22,750 --> 00:17:24,750
of treatment and nothing's worked.
228
00:17:24,750 --> 00:17:27,070
I think the name
treatment-resistant depression
229
00:17:27,070 --> 00:17:28,900
is really a bad name 'cause you can't say
230
00:17:28,900 --> 00:17:32,605
that John's depression
is resitant to treatment.
231
00:17:32,605 --> 00:17:35,160
It's just that we haven't
found the right treatments yet.
232
00:17:35,160 --> 00:17:36,540
- How are you feeling today?
233
00:17:36,540 --> 00:17:39,780
- All right, certainly more
positive than I was before,
234
00:17:39,780 --> 00:17:40,613
I am,
235
00:17:40,613 --> 00:17:44,370
but I definitely felt
that there was something
236
00:17:44,370 --> 00:17:46,745
I couldn't achieve on the first dose.
237
00:17:46,745 --> 00:17:49,970
It felt like I could
identify there was a problem,
238
00:17:49,970 --> 00:17:54,490
but I couldn't quite grasp
it or tackle it, you know?
239
00:17:54,490 --> 00:17:57,440
It's not like I'm feeling euphoria or high
240
00:17:57,440 --> 00:18:02,333
or happiness or, I just
don't feel rubbish, you know?
241
00:18:03,860 --> 00:18:07,033
And so if this is all it
does, then that's fine.
242
00:18:09,570 --> 00:18:11,853
But hopefully it'll do more.
243
00:18:30,747 --> 00:18:33,890
- I'd just really like to
get to the bottom of it
244
00:18:33,890 --> 00:18:37,833
or have somebody help me
get to the bottom of it.
245
00:18:40,750 --> 00:18:42,640
- Difficult to know what to expect.
246
00:18:42,640 --> 00:18:45,120
I sort of feel like I
don't know him well enough
247
00:18:45,120 --> 00:18:47,730
as perhaps we should at this stage,
248
00:18:47,730 --> 00:18:49,193
so that doesn't feel ideal.
249
00:18:50,200 --> 00:18:52,090
It's the low dose today.
250
00:18:52,090 --> 00:18:55,010
Essentially, I know
he'll be fine physically,
251
00:18:55,010 --> 00:18:58,270
so let's just go into it
with the right attitude,
252
00:18:58,270 --> 00:19:00,613
really, and support him.
253
00:19:04,630 --> 00:19:06,826
- Do you feel ready
to take the capsules now?
254
00:19:06,826 --> 00:19:09,326
- Yeah, I'm fine to take that.
255
00:19:12,865 --> 00:19:16,615
- Here's a glass of
water for you, all right?
256
00:19:25,186 --> 00:19:29,340
- Mark hasn't really revealed
to us why he's depressed.
257
00:19:29,340 --> 00:19:33,000
I don't think he knows, and now the taking
258
00:19:33,000 --> 00:19:38,000
of this drug is about trying to understand
259
00:19:38,070 --> 00:19:42,445
where this is coming
from, what this block is.
260
00:19:46,950 --> 00:19:49,080
- I can't pinpoint a date or an event
261
00:19:49,080 --> 00:19:51,243
that could possibly be the cause of it.
262
00:19:52,730 --> 00:19:56,483
Over all this time, I think it
must be something biological.
263
00:20:00,370 --> 00:20:01,800
I don't expect a magic wand,
264
00:20:01,800 --> 00:20:05,137
to go, "Wow, you feel
all the sudden great,
265
00:20:05,137 --> 00:20:06,937
"and you're you for doing anything!"
266
00:20:08,960 --> 00:20:11,400
Kind of what I do expect
is just not to feel
267
00:20:11,400 --> 00:20:15,490
so cripplingly negative about everything
268
00:20:15,490 --> 00:20:19,265
that it infringes upon my daily life.
269
00:20:25,090 --> 00:20:27,370
- Are you hopeful?
270
00:20:27,370 --> 00:20:31,733
I am hopeful for Mark
because if I wasn't hopeful,
271
00:20:32,650 --> 00:20:34,453
that would be a problem in itself.
272
00:20:39,370 --> 00:20:42,250
I firmly believe that this drug
273
00:20:42,250 --> 00:20:47,250
is a route out of what can
other be an insoluble problem.
274
00:20:55,010 --> 00:21:00,010
- The nature of the drug
effects are that they induce
275
00:21:00,120 --> 00:21:02,680
a kind of malleability or plasticity,
276
00:21:02,680 --> 00:21:07,170
so like they free things
up so that they can change.
277
00:21:07,170 --> 00:21:10,470
And I think what can be
characteristic of depression
278
00:21:10,470 --> 00:21:14,105
is that there are things
that aren't conscious
279
00:21:14,105 --> 00:21:18,023
and you don't realize the
contribution to your state.
280
00:21:19,243 --> 00:21:22,427
- Yeah, that all makes, it makes sense.
281
00:21:23,478 --> 00:21:26,460
- Yeah.
- Yeah.
282
00:21:26,460 --> 00:21:28,740
- Well, I hope you have a nice--
283
00:21:28,740 --> 00:21:29,828
- Yeah.
- And easy evening.
284
00:21:29,828 --> 00:21:31,620
If ever you're worried about anything
285
00:21:31,620 --> 00:21:34,540
or you just wanna ask anything,
you can give me a call.
286
00:21:34,540 --> 00:21:35,373
- Okay.
287
00:21:43,249 --> 00:21:44,540
- There are 16 ways in which drugs
288
00:21:44,540 --> 00:21:46,840
can do harm to you or to society.
289
00:21:46,840 --> 00:21:49,050
There are nine ways
they can harm the user,
290
00:21:49,050 --> 00:21:51,820
and those are the blues bars,
and the size of the red bar,
291
00:21:51,820 --> 00:21:53,800
the harm of the drug to society.
292
00:21:53,800 --> 00:21:56,960
So alcohol is the most harmful
drug in Europe and the UK,
293
00:21:56,960 --> 00:21:59,640
and the reason for that is
the size of that red bar.
294
00:21:59,640 --> 00:22:01,770
It's not the most
damaging drug to the user.
295
00:22:01,770 --> 00:22:04,440
Being on to the right,
then you have heroin
296
00:22:04,440 --> 00:22:06,530
and crack and methamphetamine.
297
00:22:06,530 --> 00:22:07,700
They have bigger blue bars.
298
00:22:07,700 --> 00:22:09,810
And the drugs that the
media get hysterical about,
299
00:22:09,810 --> 00:22:10,940
they're on the right-hand.
300
00:22:10,940 --> 00:22:14,242
They're ecstasy, LSD, magic mushrooms.
301
00:22:14,242 --> 00:22:16,120
They have virtually no harm to society
302
00:22:16,120 --> 00:22:19,473
and considerably less harm
to the user than alcohol.
303
00:22:20,500 --> 00:22:23,380
Making these drugs illegal
stops people researching them,
304
00:22:23,380 --> 00:22:24,737
even though the UN Convention said,
305
00:22:24,737 --> 00:22:27,277
"Oh, no, we're perfectly happy for you
306
00:22:27,277 --> 00:22:28,627
"to carry on researching them.
307
00:22:28,627 --> 00:22:31,330
"You just have to comply
with the regulations."
308
00:22:31,330 --> 00:22:34,560
No one has managed to get
through those regulations
309
00:22:34,560 --> 00:22:38,060
to do clinical trial of LSD in 50 years.
310
00:22:38,060 --> 00:22:41,030
- And what do you think
does have to happen
311
00:22:41,030 --> 00:22:44,290
in order for decriminalization
to happen in the UK?
312
00:22:44,290 --> 00:22:46,520
Like, is it with a politician,
313
00:22:46,520 --> 00:22:47,430
or is it with the research?
314
00:22:47,430 --> 00:22:48,624
Is it with the people, what--
315
00:22:48,624 --> 00:22:49,710
- What has to happen is we've gotta have
316
00:22:49,710 --> 00:22:52,460
completely public debate,
and you've gotta hold MPs
317
00:22:52,460 --> 00:22:56,660
up to account when they are
either not discussing this
318
00:22:56,660 --> 00:22:58,100
or talking rubbish about it.
319
00:22:58,100 --> 00:23:00,020
And the media, too, you know?
320
00:23:00,020 --> 00:23:02,020
When are people lying
about the harms of drugs,
321
00:23:02,020 --> 00:23:04,569
you've gotta challenge them all the time.
322
00:23:07,120 --> 00:23:09,700
- Baroness Molly
Meacher has spent 10 years
323
00:23:09,700 --> 00:23:12,010
as a crossbencher in the House of Lords
324
00:23:12,010 --> 00:23:14,433
campaigning for the
liberalization of drug laws.
325
00:23:15,720 --> 00:23:18,730
- UK governments tend
to be very conservative
326
00:23:18,730 --> 00:23:22,750
on drug policy, much more conservative
327
00:23:22,750 --> 00:23:25,440
than many Western European countries
328
00:23:25,440 --> 00:23:28,341
and of course the vast
majority of U.S. states.
329
00:23:28,341 --> 00:23:31,420
And that's something to do
with our media, I think.
330
00:23:31,420 --> 00:23:33,950
They've been very hostile
to reform in this area,
331
00:23:33,950 --> 00:23:35,552
which is probably something to do
332
00:23:35,552 --> 00:23:39,219
with the conservatism
of the British people.
333
00:23:41,528 --> 00:23:42,960
- So where are we off to now?
334
00:23:42,960 --> 00:23:45,620
- We're gonna go and pick up the capsules.
335
00:23:45,620 --> 00:23:49,100
It's the second dose now, so this is where
336
00:23:49,100 --> 00:23:51,523
things get even more interesting.
337
00:23:52,400 --> 00:23:55,193
It's gonna be quite a
high dose, 25 milligrams.
338
00:23:56,780 --> 00:23:58,010
- And why are they down here?
339
00:23:58,010 --> 00:23:59,597
- Oh, it's in, hi, Matt, how's it going?
340
00:23:59,597 --> 00:24:01,200
- All right, let's get the key out.
341
00:24:01,200 --> 00:24:02,670
- Sure!
342
00:24:02,670 --> 00:24:06,020
So the drug has to be stored securely.
343
00:24:06,020 --> 00:24:08,880
In order to do research
with Schedule I drugs,
344
00:24:08,880 --> 00:24:13,880
we a Home Office license, so
it's stored in this secure area
345
00:24:14,440 --> 00:24:19,164
in a locked safe that's
actually bolted to the wall.
346
00:24:21,830 --> 00:24:22,880
- What exactly is this?
347
00:24:22,880 --> 00:24:27,510
- This is psilocybin, so this
is the psychoactive ingredient
348
00:24:27,510 --> 00:24:29,270
in so-called magic mushrooms.
349
00:24:29,270 --> 00:24:30,103
- How does that compare
350
00:24:30,103 --> 00:24:32,230
to the sort of recreational dose?
351
00:24:32,230 --> 00:24:33,800
- It's quite a high dose, actually,
352
00:24:33,800 --> 00:24:36,280
2 1/2 grams of mushroom material
353
00:24:36,280 --> 00:24:39,810
or you know, hundreds, a couple of hundred
354
00:24:39,810 --> 00:24:42,010
little liberty cap magic mushrooms.
355
00:24:42,010 --> 00:24:46,000
So anyone doing that,
you'd consider really
356
00:24:46,000 --> 00:24:48,533
taking quite a high dose, so yeah,
357
00:24:49,535 --> 00:24:51,105
there's no messing about.
358
00:24:56,410 --> 00:24:57,823
- So I'm ready for the exam.
359
00:25:03,610 --> 00:25:06,710
You can't go on living like you have done
360
00:25:06,710 --> 00:25:09,110
for the last 20 years because
it doesn't get better.
361
00:25:09,110 --> 00:25:10,323
It does get worse.
362
00:25:12,240 --> 00:25:16,210
Yeah, when I think back to
late November last year,
363
00:25:16,210 --> 00:25:19,193
that was about as bad as it had got.
364
00:25:20,630 --> 00:25:23,223
And that was, that scared me.
365
00:25:30,530 --> 00:25:31,993
But we're beyond that.
366
00:25:34,230 --> 00:25:36,080
I'm extraordinarily lucky to be here.
367
00:26:00,791 --> 00:26:03,541
- Please go away, please go away!
368
00:26:04,541 --> 00:26:07,124
Oh, please go away, oh god, no!
369
00:26:10,928 --> 00:26:13,619
No, no, no, no, no, no, no, no, no!
370
00:26:13,619 --> 00:26:18,619
No, no, no, no, no!
371
00:26:23,061 --> 00:26:24,100
- Hey, Andy.
372
00:26:24,100 --> 00:26:26,310
- No, no!
- Andy, it's okay.
373
00:26:26,310 --> 00:26:28,300
With Andy, if you asked him what had been
374
00:26:28,300 --> 00:26:29,980
making him struggle or depressed,
375
00:26:29,980 --> 00:26:31,810
he would say experiences with his work
376
00:26:31,810 --> 00:26:33,721
and not feeling good enough there,
377
00:26:33,721 --> 00:26:37,750
but that didn't even come
into the sessions at all,
378
00:26:37,750 --> 00:26:41,110
and it was more about his
early childhood experiences
379
00:26:41,110 --> 00:26:42,900
of suffering in pain.
380
00:26:42,900 --> 00:26:44,302
- I need more spaghetti.
- Does it want to come inside?
381
00:26:44,302 --> 00:26:45,738
- I need more spaghetti.
382
00:26:45,738 --> 00:26:47,368
- Okay, what about letting it in?
383
00:26:47,368 --> 00:26:48,529
We're here with you, Andy, now.
384
00:26:48,529 --> 00:26:50,678
- No, no, no, no, no, no.
385
00:26:50,678 --> 00:26:51,950
No, no.
- Okay.
386
00:26:51,950 --> 00:26:53,550
These kind of early childhood experiences
387
00:26:53,550 --> 00:26:55,650
will often be repressed.
388
00:26:55,650 --> 00:26:56,810
People can go through their whole lives
389
00:26:56,810 --> 00:27:00,360
without ever really facing those demons,
390
00:27:00,360 --> 00:27:02,820
but it's not as if the
demons they've pushed down
391
00:27:02,820 --> 00:27:05,310
don't cause any suffering
because they're there.
392
00:27:05,310 --> 00:27:07,760
- This is so
393
00:27:07,760 --> 00:27:10,140
- Just let it be here and see
what it's here to show you.
394
00:27:10,140 --> 00:27:12,140
- Oh, god.
- And know that you're safe.
395
00:27:13,968 --> 00:27:18,968
- I'm afraid it won't go away,
won't go away, won't go away.
396
00:27:20,720 --> 00:27:22,770
- Just a small improvement
would be lovely,
397
00:27:22,770 --> 00:27:25,690
just for him to feel
differently about things
398
00:27:25,690 --> 00:27:28,800
and see the world through
a different pair of eyes.
399
00:27:56,619 --> 00:27:57,870
- Hello!
400
00:27:57,870 --> 00:28:00,120
- Andy!
- How are you doing?
401
00:28:02,084 --> 00:28:04,070
- How was it?
402
00:28:04,070 --> 00:28:07,163
- Yeah, yeah.
- Oh!
403
00:28:09,289 --> 00:28:13,930
- Extraordinary, extraordinary.
404
00:28:13,930 --> 00:28:15,290
- Is that different from last time?
405
00:28:15,290 --> 00:28:17,250
- Yeah, yes, yeah, yeah.
406
00:28:17,250 --> 00:28:21,039
You knew that this was the big ride.
407
00:28:21,039 --> 00:28:25,743
This is the one that changed things.
408
00:28:27,210 --> 00:28:31,570
And of course, it's left lots
and lots of questions, really,
409
00:28:32,710 --> 00:28:36,310
but those I think the answers to those
410
00:28:36,310 --> 00:28:37,914
will come out in good time.
411
00:28:37,914 --> 00:28:39,423
- Yeah.
- Dad was there.
412
00:28:39,423 --> 00:28:40,552
- Yes.
- Dad was there.
413
00:28:40,552 --> 00:28:41,503
- Good.
- Yeah.
414
00:28:41,503 --> 00:28:42,543
- Oh, that's lovely.
415
00:28:42,543 --> 00:28:45,310
- Yeah, couple a times, actually.
416
00:28:45,310 --> 00:28:47,270
Couple a times he was there.
- Yes.
417
00:28:47,270 --> 00:28:50,400
- Where it was headed was dangerous to me.
418
00:28:50,400 --> 00:28:52,383
It was a dangerous path, but no, no.
419
00:28:54,520 --> 00:28:57,910
It's all, we're okay now, we're okay.
420
00:28:57,910 --> 00:28:58,760
- You're right.
421
00:28:58,760 --> 00:28:59,823
- All is resolved.
422
00:29:01,383 --> 00:29:02,216
- Bye-bye.
423
00:29:02,216 --> 00:29:03,049
- See you tomorrow.
424
00:29:03,049 --> 00:29:03,882
Cheerio.
425
00:29:03,882 --> 00:29:05,549
Have a nice evening.
426
00:29:06,600 --> 00:29:09,180
- I could feel that he
was suffering so much,
427
00:29:09,180 --> 00:29:10,880
but I could also feel that
it was really important
428
00:29:10,880 --> 00:29:13,650
for him to be suffering,
so I was kind of pleased
429
00:29:13,650 --> 00:29:16,010
in a weird way that he was
going through it,
430
00:29:16,010 --> 00:29:17,967
thinking, "Yes, now we're
getting to the stuff," you know?
431
00:29:17,967 --> 00:29:19,857
"This is what's been causing
you so much suffering,
432
00:29:19,857 --> 00:29:21,890
"so we need to get it out."
433
00:29:21,890 --> 00:29:26,890
And he was really in a battle
with a large, dark, evil force
434
00:29:30,858 --> 00:29:33,879
that he associated with his mum.
435
00:29:37,997 --> 00:29:39,497
- Get away.
436
00:29:44,588 --> 00:29:45,421
Get away.
437
00:29:48,226 --> 00:29:49,976
You're not coming in.
438
00:29:51,550 --> 00:29:55,683
- There was so much
darkness and so much pain.
439
00:29:56,560 --> 00:29:59,897
There were moments of thinking,
"Where is this gonna go?
440
00:29:59,897 --> 00:30:01,150
"How's it gonna be by the end of the day?"
441
00:30:01,150 --> 00:30:03,680
You know, what if this
doesn't get resolved?
442
00:30:03,680 --> 00:30:05,150
There was a sense from the last session
443
00:30:05,150 --> 00:30:08,100
of his dad being kind of wonderful,
444
00:30:08,100 --> 00:30:10,300
and his mum being kind
of terrible and evil.
445
00:30:11,368 --> 00:30:14,913
- We're all done and dead.
446
00:30:18,019 --> 00:30:22,200
I'm telling you, we're
all dead, we're all dead.
447
00:30:22,200 --> 00:30:24,030
- What sort of evolved out of today
448
00:30:24,030 --> 00:30:26,440
is that it really doesn't matter.
449
00:30:26,440 --> 00:30:28,807
If there was one person doing right,
450
00:30:28,807 --> 00:30:32,440
the other one doing wrong,
what actually matters
451
00:30:32,440 --> 00:30:35,080
at the end is resolution and love
452
00:30:35,080 --> 00:30:39,500
because that is the big thing
that came out for me today
453
00:30:39,500 --> 00:30:42,670
is that the more you hate something,
454
00:30:42,670 --> 00:30:45,150
the more you feed it with that hate,
455
00:30:45,150 --> 00:30:48,540
the bigger it gets, and
that's what's been going on.
456
00:30:48,540 --> 00:30:52,850
I've been feeding this thing,
it's been consuming me,
457
00:30:52,850 --> 00:30:54,650
and now I've got to the realization
458
00:30:54,650 --> 00:30:57,650
that if I stop feeding it with hate,
459
00:30:57,650 --> 00:30:59,880
it evaporates, it goes away.
460
00:31:01,322 --> 00:31:05,223
Shh, it's, oh, yes, yes, yes.
461
00:31:13,223 --> 00:31:14,194
- Are you out?
462
00:31:14,194 --> 00:31:15,027
- Ah!
463
00:31:21,427 --> 00:31:24,003
And as soon as that realization occurred,
464
00:31:25,330 --> 00:31:29,380
because I had the
representation of my father
465
00:31:29,380 --> 00:31:32,660
and Vonnie and the boys on my chest,
466
00:31:32,660 --> 00:31:36,200
but I didn't have a representation of Mom.
467
00:31:36,200 --> 00:31:41,123
So I took a picture and
brought here in to that union,
468
00:31:42,200 --> 00:31:47,200
really, at the end, and
we were kinda one again,
469
00:31:48,700 --> 00:31:50,443
but one helluva a battle.
470
00:31:52,893 --> 00:31:54,623
I wouldn't wanna do it again.
471
00:31:56,100 --> 00:31:58,980
I've been the happiest ever in my life,
472
00:31:58,980 --> 00:32:03,230
and I've been the most
terrified in my life
473
00:32:03,230 --> 00:32:07,720
in the same day, probably in
the space of half an hour.
474
00:32:07,720 --> 00:32:08,867
- So good.
475
00:32:08,867 --> 00:32:10,123
- Mm, really good.
476
00:32:11,460 --> 00:32:15,670
Exhausting, but really, really, very good.
477
00:32:15,670 --> 00:32:18,442
And I mean, well, the proof
is in the pudding, you know?
478
00:32:18,442 --> 00:32:21,070
Today was good, it was intense.
479
00:32:21,070 --> 00:32:23,630
It was good, it was tough,
all the things I hope for,
480
00:32:23,630 --> 00:32:27,600
but we will see how Andy's
feeling tomorrow, next week.
481
00:32:27,600 --> 00:32:30,630
And the really key thing
is in a week, a month,
482
00:32:30,630 --> 00:32:34,063
few months, that's
what's really important.
483
00:32:43,050 --> 00:32:46,173
- Hi, good to see you, how you doing?
484
00:32:46,173 --> 00:32:47,190
- All right, yeah, yourself?
485
00:32:47,190 --> 00:32:48,721
- Yeah, we're all right, yeah.
486
00:32:48,721 --> 00:32:49,554
- Yeah?
- Yeah.
487
00:32:49,554 --> 00:32:51,120
My mind's been racing about, you know,
488
00:32:51,120 --> 00:32:53,087
what could be or how could be.
489
00:32:56,413 --> 00:32:57,246
- And you have
490
00:32:57,246 --> 00:33:01,910
- Oh yeah, yeah, but more
about what it could be
491
00:33:01,910 --> 00:33:03,400
that's coming .
492
00:33:03,400 --> 00:33:05,340
- I think we should get into the room
493
00:33:05,340 --> 00:33:08,720
well ahead of time and settle
down and talk to the others.
494
00:33:11,513 --> 00:33:13,323
- Okay.
- If you remember last time.
495
00:33:13,323 --> 00:33:14,156
- Okay.
496
00:33:23,200 --> 00:33:25,520
- Last week we had somebody in the study
497
00:33:25,520 --> 00:33:28,340
who had a particularly strong
response to psilocybin,
498
00:33:28,340 --> 00:33:31,060
probably the strongest
psychedelic experience
499
00:33:31,060 --> 00:33:35,050
I've ever sat with, and
that's kind of raised,
500
00:33:35,050 --> 00:33:37,940
raised my kind of alertness,
really, about today.
501
00:33:37,940 --> 00:33:40,730
It's just a reminder, really,
never to underestimate
502
00:33:41,945 --> 00:33:45,340
the power, really, of a psychedelic drug
503
00:33:45,340 --> 00:33:49,773
and the alterations in
consciousness that they can induce.
504
00:33:51,340 --> 00:33:53,050
- Tell us what's on your mind?
505
00:33:53,050 --> 00:33:56,233
- I don't know why, it
just feels like it stopped.
506
00:33:56,233 --> 00:33:59,142
It feels like it, I just wanna
go home, that's what I want.
507
00:33:59,142 --> 00:33:59,975
- Just wanna go home.
508
00:33:59,975 --> 00:34:00,808
- Yeah.
- How come?
509
00:34:00,808 --> 00:34:04,053
- I don't know, it just,
that's just, I mean.
510
00:34:05,670 --> 00:34:06,503
Did you really get--
511
00:34:06,503 --> 00:34:09,370
- Today John nearly left, which
was quite a dilemma for us
512
00:34:09,370 --> 00:34:12,150
because on the one, we
want to keep him here
513
00:34:12,150 --> 00:34:14,353
and keep him safe, but
we also didn't wanna
514
00:34:14,353 --> 00:34:15,800
keep him here against his will.
515
00:34:15,800 --> 00:34:18,280
And so it was difficult.
516
00:34:18,280 --> 00:34:20,290
- It's probably a bit
early for you to go as yet.
517
00:34:20,290 --> 00:34:22,070
I mean, can you just hold
off a little bit longer?
518
00:34:22,070 --> 00:34:24,650
- I don't know, just wanna go home today.
519
00:34:24,650 --> 00:34:27,900
- Yeah, is there anything at all?
520
00:34:27,900 --> 00:34:29,343
- There was just, I think,
521
00:34:32,364 --> 00:34:33,879
well, when I close my eyes and try and,
522
00:34:33,879 --> 00:34:35,660
I try and sleep, I just will feel like
523
00:34:35,660 --> 00:34:37,973
when a bad dream in to the next.
524
00:34:39,705 --> 00:34:41,840
That what it feels like.
525
00:34:41,840 --> 00:34:44,260
- It wasn't really what I
would've planned or expected.
526
00:34:44,260 --> 00:34:46,210
I didn't even realize
that's what John needed,
527
00:34:46,210 --> 00:34:49,039
but looking back, I see
it was what he needed.
528
00:34:49,039 --> 00:34:51,210
It was like the first dose
was like lulling him into it.
529
00:34:51,210 --> 00:34:53,990
It gave him a sense of
it's okay, I can do this.
530
00:34:53,990 --> 00:34:56,250
And then the second dose, it's like,
531
00:34:56,250 --> 00:34:58,003
right, now the real work begins.
532
00:35:00,207 --> 00:35:03,253
- Okay, I probably should've left.
533
00:35:03,253 --> 00:35:05,730
- And the real work isn't experiencing
534
00:35:05,730 --> 00:35:08,240
some lovely feeling of
love from the world.
535
00:35:08,240 --> 00:35:12,070
The work is going on a
journey within yourself,
536
00:35:12,070 --> 00:35:14,430
finding that nugget of pain,
537
00:35:14,430 --> 00:35:16,653
and integrating it into your life.
538
00:35:26,630 --> 00:35:30,303
- I'm really hoping and
praying that it has worked.
539
00:35:31,240 --> 00:35:33,970
Up until now, with John being ill,
540
00:35:33,970 --> 00:35:37,860
I've been mum and dad to the kids.
541
00:35:37,860 --> 00:35:42,600
And now, it might be that I can share
542
00:35:42,600 --> 00:35:45,333
the load again and it won't just be me.
543
00:35:45,333 --> 00:35:49,120
It's be me and John working as a team
544
00:35:49,120 --> 00:35:52,057
like we used to do all those years ago.
545
00:35:56,330 --> 00:35:58,582
- Your wife's over here.
546
00:35:58,582 --> 00:35:59,415
- Hello!
547
00:36:00,785 --> 00:36:01,705
How're you feeling?
548
00:36:01,705 --> 00:36:04,644
2 1/2 .
549
00:36:04,644 --> 00:36:06,094
- Really?
550
00:36:06,094 --> 00:36:09,650
- Yeah.
551
00:36:09,650 --> 00:36:10,825
Oh, I nearly left.
552
00:36:10,825 --> 00:36:11,658
- Why?
553
00:36:11,658 --> 00:36:14,893
- It was just, I got upset, horrible.
554
00:36:16,050 --> 00:36:18,639
And then they, some very kind people
555
00:36:18,639 --> 00:36:20,827
convinced me to stay in the room.
556
00:36:20,827 --> 00:36:22,280
- Did they tie you down?
557
00:36:22,280 --> 00:36:23,895
- No, no, they--
558
00:36:23,895 --> 00:36:25,376
- Really, really.
- It was physical.
559
00:36:25,376 --> 00:36:26,663
- Actually--
- No physical restraint.
560
00:36:26,663 --> 00:36:28,910
- I think a lot's been
sort of experienced today.
561
00:36:28,910 --> 00:36:29,743
- Okay.
562
00:36:29,743 --> 00:36:34,160
- And been, yeah, just a
little rockier than last time?
563
00:36:35,247 --> 00:36:36,768
- Oh, yeah, yeah.
564
00:36:36,768 --> 00:36:40,617
- At one point, but I think
maybe because of that,
565
00:36:43,030 --> 00:36:48,030
maybe there's more benefits
being had from this experience--
566
00:36:48,067 --> 00:36:49,008
- Yeah.
- Than last week.
567
00:36:49,008 --> 00:36:51,397
- Yeah, it was bad in
terms of what I experienced
568
00:36:51,397 --> 00:36:53,730
but necessary for actually--
569
00:36:55,096 --> 00:36:55,929
- Does that mean you can
570
00:36:55,929 --> 00:36:56,880
get rid of the beard, John?
571
00:36:56,880 --> 00:36:58,307
- No, yeah--
- Oh!
572
00:36:58,307 --> 00:36:59,408
- A miner poked me and said,
573
00:36:59,408 --> 00:37:00,650
"Grow it till it's down to your knees!"
574
00:37:00,650 --> 00:37:02,430
- Oh!
575
00:37:02,430 --> 00:37:04,440
- At first, I really didn't
think it was working.
576
00:37:04,440 --> 00:37:08,520
It wasn't until the very
end when I could set
577
00:37:08,520 --> 00:37:11,260
and then reflect on it that I
could see what had happened.
578
00:37:11,260 --> 00:37:13,780
All these things that happened
to me when I was a kid,
579
00:37:13,780 --> 00:37:16,130
it made me face very single one of 'em,
580
00:37:16,130 --> 00:37:18,580
and nobody wants to do that.
581
00:37:18,580 --> 00:37:22,160
But yeah, so it was an
extremely horrible afternoon,
582
00:37:22,160 --> 00:37:24,200
the worst experience in my life.
583
00:37:24,200 --> 00:37:26,260
Sometimes I could hear bugs,
584
00:37:26,260 --> 00:37:28,550
as if a bug was crawling
through the ground.
585
00:37:28,550 --> 00:37:32,120
The images that I saw was of this massive
586
00:37:32,120 --> 00:37:35,030
sort of black-and-red iron thing
587
00:37:35,030 --> 00:37:37,010
with huge spikes pointing into it.
588
00:37:37,010 --> 00:37:39,370
But the experience that it relates to was
589
00:37:39,370 --> 00:37:41,210
when some took my T-shirt off
590
00:37:41,210 --> 00:37:44,240
and threw me in this
massive patch of nettles,
591
00:37:44,240 --> 00:37:47,823
and I was beat with a hawthorn branches,
592
00:37:47,823 --> 00:37:50,630
and the bugs that I heard were the bugs
593
00:37:50,630 --> 00:37:54,190
that I heard when I was on
the ground afterwards crying.
594
00:37:54,190 --> 00:37:57,233
The sharp spikes on the
big black-and-red thing
595
00:37:57,233 --> 00:38:01,030
were the thorns on the branch.
596
00:38:01,030 --> 00:38:04,140
It was almost like absolutely everything
597
00:38:04,140 --> 00:38:07,000
was trying its hardest to
see this is the problem.
598
00:38:07,000 --> 00:38:11,910
You know, it makes me feel that depression
599
00:38:11,910 --> 00:38:16,030
is a way we cope, as a kid we build up
600
00:38:16,030 --> 00:38:19,981
psychological protections
for ourself
601
00:38:19,981 --> 00:38:22,240
but at some point in your adult life,
602
00:38:22,240 --> 00:38:25,603
we have to come terms with
that and deal with it,
603
00:38:26,612 --> 00:38:30,260
and there is no natural part of life
604
00:38:30,260 --> 00:38:32,960
that we have in modern society
that allows that to happen.
605
00:38:32,960 --> 00:38:36,110
Counseling doesn't do it,
antidepressants won't do it.
606
00:38:36,110 --> 00:38:39,300
But this thing does do that.
607
00:38:39,300 --> 00:38:42,770
It takes you straight there,
exactly what Robin promised.
608
00:38:42,770 --> 00:38:43,690
It will take you to that place.
609
00:38:43,690 --> 00:38:47,270
Whatever the problem is, it
will take you straight to that,
610
00:38:47,270 --> 00:38:51,520
and you have to decide there and then
611
00:38:51,520 --> 00:38:54,100
whether you're going
to be a victim of that
612
00:38:54,100 --> 00:38:56,313
for the rest of your life or not.
613
00:38:56,313 --> 00:38:57,146
- John?
614
00:38:58,905 --> 00:39:00,145
- What?
- Hi, John.
615
00:39:00,145 --> 00:39:01,113
How you doing?
616
00:39:01,113 --> 00:39:02,204
- Doing much better.
617
00:39:02,204 --> 00:39:04,453
- Great, that's good to know.
- Good.
618
00:39:04,453 --> 00:39:06,170
- What I was just thinking
was it wasn't some
619
00:39:06,170 --> 00:39:07,890
external spiritual force,
620
00:39:07,890 --> 00:39:11,048
or it wasn't someone's
counseling technique.
621
00:39:13,900 --> 00:39:16,650
It's actually oneself that
does the healing in the end.
622
00:39:32,660 --> 00:39:34,750
- You look at these images,
you can see the cortex.
623
00:39:34,750 --> 00:39:36,730
That the outer part of the brain here.
624
00:39:36,730 --> 00:39:39,610
And this is a kind of spine to the cortex,
625
00:39:39,610 --> 00:39:43,730
and this seem to be particularly
implicated in depression.
626
00:39:43,730 --> 00:39:46,560
Now, what psilocybin does is to introduce
627
00:39:46,560 --> 00:39:49,360
a degree of chaos, if you want,
628
00:39:49,360 --> 00:39:51,430
almost like a kind of scrambling effect
629
00:39:51,430 --> 00:39:54,360
as a kind of resetting of the brain,
630
00:39:54,360 --> 00:39:59,010
and it sort of settles in
a healthy mode of function.
631
00:39:59,010 --> 00:40:00,346
- Oh, that's the
reason for the scans,
632
00:40:00,346 --> 00:40:01,179
for the definite--
633
00:40:01,179 --> 00:40:03,163
- That's what we're
doing now, really, yeah.
634
00:40:04,004 --> 00:40:04,907
- It's really interesting.
635
00:40:04,907 --> 00:40:06,887
- Yeah.
636
00:40:19,750 --> 00:40:20,660
- Tell us whether
you'd have been able
637
00:40:20,660 --> 00:40:22,838
to walk around London a month ago.
638
00:40:22,838 --> 00:40:23,817
- No, I wouldn't have done that.
639
00:40:23,817 --> 00:40:25,320
Coming in here, a place in London,
640
00:40:25,320 --> 00:40:26,740
the corner of Oxford
Street and Regent Street
641
00:40:26,740 --> 00:40:30,320
where it's so mobbed, I just
wouldn't have done that.
642
00:40:30,320 --> 00:40:31,280
I'm enjoying that, you know?
643
00:40:31,280 --> 00:40:34,530
It's nice, you're not sitting
thinking about yourself
644
00:40:34,530 --> 00:40:37,040
or thinking about anything depressing
645
00:40:37,040 --> 00:40:39,090
or bad or dark or deep.
646
00:40:39,090 --> 00:40:42,078
It feels good, it feels like
there's a lightness, you know?
647
00:40:42,078 --> 00:40:44,761
That is like a burden that's been lifted.
648
00:40:44,761 --> 00:40:45,675
That's what it feels like.
649
00:40:45,675 --> 00:40:49,090
It's like someone's just come
along, and they've taken away
650
00:40:49,090 --> 00:40:50,990
everything that was weighing you down.
651
00:41:05,500 --> 00:41:07,360
- Today, I just really wanna get it
652
00:41:07,360 --> 00:41:08,770
over and done with, basically.
653
00:41:08,770 --> 00:41:12,010
I don't really have any
hopes or predictions
654
00:41:12,010 --> 00:41:16,483
or ideas about what
might happen or really...
655
00:41:24,234 --> 00:41:27,567
Let's just get on with it, really, yeah.
656
00:42:28,173 --> 00:42:32,360
- I feel really tired, hungover.
657
00:42:32,360 --> 00:42:35,350
Massively abnormal
feelings forming that I've,
658
00:42:35,350 --> 00:42:39,310
not sure if I've ever
experienced in my adult life.
659
00:42:39,310 --> 00:42:41,460
- Do you feel like
it's something that's,
660
00:42:41,460 --> 00:42:43,521
you'd want to work on?
661
00:42:43,521 --> 00:42:47,880
- I kinda wanna work on it,
662
00:42:47,880 --> 00:42:51,490
'cause I don't wanna
feel like this or yeah,
663
00:42:51,490 --> 00:42:53,350
feel like this or how I've felt
664
00:42:53,350 --> 00:42:56,890
for the majority of my life anymore.
665
00:42:56,890 --> 00:42:58,630
There was nothing that like linked back
666
00:42:58,630 --> 00:43:01,163
to like this is what
caused your depression.
667
00:43:02,180 --> 00:43:04,900
You know, you use these
tools and work it out.
668
00:43:04,900 --> 00:43:09,580
And it's like it's still
a massive mystery to me.
669
00:43:09,580 --> 00:43:11,003
- And is that disappointing?
670
00:43:13,130 --> 00:43:18,130
- It's no more disappointing
than every other day,
671
00:43:18,750 --> 00:43:21,483
so yeah.
672
00:43:38,509 --> 00:43:40,899
- How old were you when
you came to ?
673
00:43:40,899 --> 00:43:43,450
- I'm just trying to think.
674
00:43:43,450 --> 00:43:47,833
I know the first Christmas
I had a red trike,
675
00:43:49,400 --> 00:43:53,193
so I'd gotta be 3 1/2 or three.
676
00:44:00,090 --> 00:44:03,543
Somehow it looked, it's so
much smaller than I remember.
677
00:44:05,220 --> 00:44:08,200
And you saw the little
window on the ground floor.
678
00:44:08,200 --> 00:44:09,140
- Oh, yeah.
679
00:44:09,140 --> 00:44:13,060
- That's where I used to
sit with Lynn on the stairs
680
00:44:14,280 --> 00:44:16,323
listening to a in the lounge.
681
00:44:24,570 --> 00:44:26,400
Going into the treatment, I thought, now,
682
00:44:26,400 --> 00:44:29,010
is it gonna be the sort
of conflict I had at work,
683
00:44:29,010 --> 00:44:30,660
or is it gonna be the family?
684
00:44:30,660 --> 00:44:33,450
Strangely, I've not even thought much
685
00:44:33,450 --> 00:44:36,340
about what happened at work.
686
00:44:36,340 --> 00:44:39,003
Well, that was momentous for me then.
687
00:44:39,890 --> 00:44:43,500
It's kind of, it's automatically
just sort of drifted back
688
00:44:44,495 --> 00:44:49,123
to what went on in that house down there.
689
00:44:49,975 --> 00:44:54,223
That's where the damage was done.
690
00:44:55,260 --> 00:44:57,466
Just give me a minute down here.
691
00:45:02,980 --> 00:45:04,560
- This is probably the
third or fourth time
692
00:45:04,560 --> 00:45:07,520
we've been back as a couple
to see where he's lived.
693
00:45:07,520 --> 00:45:10,557
And all he's ever done is
remembered it with fondness.
694
00:45:10,557 --> 00:45:12,053
"This is where I grew
up, and I loved this,
695
00:45:12,053 --> 00:45:14,150
"and I did this, and I did this with Dad."
696
00:45:14,150 --> 00:45:17,193
And today, it's just more painful.
697
00:45:18,040 --> 00:45:20,370
- A change has occurred,
there's no doubt about that.
698
00:45:20,370 --> 00:45:23,726
A change has occurred, but it's not,
699
00:45:23,726 --> 00:45:26,200
it's not the easy change
700
00:45:26,200 --> 00:45:27,980
that I thought it would be.
701
00:45:27,980 --> 00:45:32,200
It's a bit as though I had ingested
702
00:45:32,200 --> 00:45:36,727
a really, really good therapist.
703
00:45:36,727 --> 00:45:38,070
That's what it feels like.
704
00:45:38,070 --> 00:45:42,443
It feels of I've got onboard
now my own therapist.
705
00:45:46,847 --> 00:45:51,847
- Okay.
706
00:46:09,680 --> 00:46:11,257
- Cheers!
- Thank you so much,
707
00:46:11,257 --> 00:46:13,988
and thanks for everything, really.
708
00:46:13,988 --> 00:46:14,946
- It's a pleasure.
709
00:46:14,946 --> 00:46:16,662
- I know it's a work in
progress, but you know,
710
00:46:16,662 --> 00:46:20,863
I think thing's are moving
in the right direction.
711
00:46:21,720 --> 00:46:23,280
I'm not sure if it's correct or not,
712
00:46:23,280 --> 00:46:25,900
but the way I look at it
is that I've been unhappy
713
00:46:25,900 --> 00:46:28,840
for so long that I think that unhappiness
714
00:46:28,840 --> 00:46:33,840
has spilled obviously into
my life and my relationships,
715
00:46:34,240 --> 00:46:37,610
and I think there's a residue
that's gotta be dealt with.
716
00:46:37,610 --> 00:46:41,510
But the other thing was
this awful image that I had
717
00:46:44,950 --> 00:46:49,950
with the smothering,
this awful image that--
718
00:46:55,353 --> 00:46:57,660
- That your dad didn't
want you, the rejection?
719
00:46:57,660 --> 00:46:58,660
- Yeah, yeah.
720
00:47:00,344 --> 00:47:01,427
What is that?
721
00:47:02,892 --> 00:47:03,725
- Let it happen.
722
00:47:03,725 --> 00:47:07,063
- Trying to make sure
they can pull out the memory.
723
00:47:07,063 --> 00:47:09,853
I could actually see the pillow,
724
00:47:11,140 --> 00:47:13,700
and then suddenly the
realization was, you know,
725
00:47:13,700 --> 00:47:15,505
that I'm being smothered.
726
00:47:25,375 --> 00:47:27,292
Oh, no, Father, no, no.
727
00:47:29,220 --> 00:47:31,073
- Stay here with us, just let it--
728
00:47:31,073 --> 00:47:34,855
- No, no, no, no, no
729
00:47:34,855 --> 00:47:36,438
no, no, no, no, no.
730
00:47:39,370 --> 00:47:43,240
That feeling was real,
then the realization
731
00:47:43,240 --> 00:47:45,353
that it was Dad doing it was real.
732
00:47:52,604 --> 00:47:55,820
Really beat up on me that badly?
733
00:47:55,820 --> 00:47:58,497
All I can remember about my dad is good,
734
00:47:58,497 --> 00:48:01,690
and that's why I think
I can't ever imagine him
735
00:48:01,690 --> 00:48:03,840
wanting to dispatch me with a pillow.
736
00:48:03,840 --> 00:48:07,380
'Cause there are lovely
memories of getting up
737
00:48:07,380 --> 00:48:10,430
at sort of 4:30 in the morning
and going on his milk route,
738
00:48:10,430 --> 00:48:14,267
you know, these crystal-clear
images of those times,
739
00:48:14,267 --> 00:48:15,830
and they were really pleasant.
740
00:48:15,830 --> 00:48:18,420
- Your mind will allow you
to remember those things,
741
00:48:18,420 --> 00:48:19,720
those positive memories.
742
00:48:19,720 --> 00:48:20,553
- Yep.
743
00:48:20,553 --> 00:48:25,080
- Anything that is
confusing or conflictual
744
00:48:25,080 --> 00:48:27,469
might be something that
you'd wanna keep away--
745
00:48:27,469 --> 00:48:29,309
- Yeah, yeah.
- From your memories
746
00:48:29,309 --> 00:48:32,340
and your conscious mind.
- Yeah, yeah.
747
00:48:32,340 --> 00:48:36,059
Okay.
- After you, are we all going?
748
00:48:36,059 --> 00:48:38,470
- Often in a psychedelic dose,
the person will experience
749
00:48:38,470 --> 00:48:41,040
the same fragility, vulnerability,
750
00:48:41,040 --> 00:48:44,430
overwhelming horror as
they did as a child,
751
00:48:44,430 --> 00:48:46,149
so I think that's what happened with Andy.
752
00:48:46,149 --> 00:48:49,260
He was stripped of his
defenses as an adult
753
00:48:49,260 --> 00:48:51,610
and taken back to that vulnerable place.
754
00:48:51,610 --> 00:48:53,690
What was real for Andy was his fear,
755
00:48:53,690 --> 00:48:57,010
fear of annihilation and
sense, huge sense of rejection,
756
00:48:57,010 --> 00:48:58,930
and that theme of rejection is something
757
00:48:58,930 --> 00:49:00,610
that has plagued him his whole life.
758
00:49:00,610 --> 00:49:03,540
So that feels like it's
really clinically significant.
759
00:49:03,540 --> 00:49:04,373
- Bye now, bye-bye.
- Bye!
760
00:49:04,373 --> 00:49:06,000
- Bye.
- Bye, Monty.
761
00:49:06,000 --> 00:49:08,560
- I wish that I would be
able to work as his therapist
762
00:49:08,560 --> 00:49:10,530
and it could be a longer
course of treatment
763
00:49:10,530 --> 00:49:13,260
and that we could perhaps
have another dosing
764
00:49:13,260 --> 00:49:15,720
and keep working on a process,
'cause then I really feel
765
00:49:15,720 --> 00:49:17,770
that huge breakthroughs could be made.
766
00:49:17,770 --> 00:49:21,500
I hope that from this
dose, there will also be
767
00:49:21,500 --> 00:49:22,760
a significant improvement.
768
00:49:22,760 --> 00:49:25,550
I think for sort of lifelong change,
769
00:49:25,550 --> 00:49:30,020
I feel that further therapy
and further dosing sessions
770
00:49:30,020 --> 00:49:31,483
would probably be required.
771
00:49:35,290 --> 00:49:36,343
- Finished?
- Yeah.
772
00:49:39,357 --> 00:49:40,190
- Should we head out?
773
00:49:40,190 --> 00:49:41,738
- Yeah.
774
00:49:44,900 --> 00:49:48,270
- One of Mark's major problems
is not his depression,
775
00:49:48,270 --> 00:49:50,900
but it's the fact that he
doesn't know what he wants,
776
00:49:50,900 --> 00:49:53,800
and he wants other people
to sort of help him
777
00:49:53,800 --> 00:49:55,853
and tell him sort of what to do.
778
00:49:56,770 --> 00:49:59,240
We've really tried to encourage him to try
779
00:49:59,240 --> 00:50:02,517
and work out a little bit
what he does want from life,
780
00:50:02,517 --> 00:50:04,020
but he, you know, he obviously,
781
00:50:04,020 --> 00:50:07,160
he still reports being quite lost.
782
00:50:07,160 --> 00:50:09,340
And so it's a delicate balance really,
783
00:50:09,340 --> 00:50:12,320
but in the therapy, I
think it will be all about
784
00:50:12,320 --> 00:50:13,980
trying to get him to have a greater sense
785
00:50:13,980 --> 00:50:15,430
of himself and what he wants.
786
00:50:33,290 --> 00:50:35,507
- I think school was tough for everyone.
787
00:50:35,507 --> 00:50:37,130
You know, I used to to in
the library and try and read
788
00:50:37,130 --> 00:50:39,688
about how to act in public, how to,
789
00:50:39,688 --> 00:50:41,943
and it just felt very,
very alien, the whole,
790
00:50:43,500 --> 00:50:47,590
you know, the whole concept
of people having girlfriends,
791
00:50:47,590 --> 00:50:50,290
people having lots of friends.
792
00:50:50,290 --> 00:50:52,790
Everyone was different, but I felt
793
00:50:52,790 --> 00:50:56,120
very removed from everyone.
794
00:50:56,120 --> 00:50:57,697
I went to the doctor's, and he said,
795
00:50:57,697 --> 00:50:59,947
"Go to Amsterdam," and I was like,
796
00:50:59,947 --> 00:51:02,560
"Mate, I'm 14," you know?
797
00:51:02,560 --> 00:51:06,900
This is 1984, you're telling
me to go to Amsterdam.
798
00:51:06,900 --> 00:51:08,953
What you expected me to do there?
799
00:51:10,210 --> 00:51:11,600
'Cause all I knew about Amsterdam
800
00:51:11,600 --> 00:51:14,840
were clogs, Anne Frank,
prostitution, and drugs,
801
00:51:14,840 --> 00:51:17,200
and it's, I didn't think he was telling me
802
00:51:17,200 --> 00:51:19,350
to go to the Anne Frank
museum, and it was,
803
00:51:20,884 --> 00:51:22,767
and I thought, "That's my GP."
804
00:51:24,380 --> 00:51:26,267
And now I've been told by doctors,
805
00:51:26,267 --> 00:51:28,177
"This is what it's gonna be like.
806
00:51:28,177 --> 00:51:30,150
"Nothing's gonna change,
you're gonna be like this."
807
00:51:30,150 --> 00:51:32,423
And then you think, or you start thinking,
808
00:51:33,327 --> 00:51:37,027
"Wow, actually, what's the
fucking point, really?"
809
00:51:38,880 --> 00:51:40,180
You know, thanks for that.
810
00:51:47,636 --> 00:51:50,040
- I grew up was a valley called
811
00:51:50,040 --> 00:51:53,570
I can still see the field and
the hawthorn sort of hedge
812
00:51:53,570 --> 00:51:54,730
where it all took place.
813
00:51:54,730 --> 00:51:58,052
I could take you straight
to the very place.
814
00:51:58,052 --> 00:51:59,440
And the thing was it didn't happen
815
00:51:59,440 --> 00:52:02,100
that far from my home, but if I ever tried
816
00:52:02,100 --> 00:52:04,960
to complain about it to my
mum, she would just go nuts,
817
00:52:04,960 --> 00:52:07,252
and she would give me a hammering.
818
00:52:07,252 --> 00:52:09,863
And then when Dad come home
from work, he would come in.
819
00:52:09,863 --> 00:52:12,320
Even if you were sleeping,
you would get woken up,
820
00:52:12,320 --> 00:52:14,840
and you'd be getting
another hammerin', you know?
821
00:52:14,840 --> 00:52:18,350
That was, I think, being
that I really started having
822
00:52:18,350 --> 00:52:20,207
sort of emotional problems,
I think, as a kid.
823
00:52:20,207 --> 00:52:21,880
- 'Cause when these
things are experienced,
824
00:52:21,880 --> 00:52:23,377
they can't be unexperienced, can they?
825
00:52:23,377 --> 00:52:26,650
And the typical response
is to try and forget them.
826
00:52:26,650 --> 00:52:28,083
- Yeah,
827
00:52:28,083 --> 00:52:33,083
- Perhaps the healthiest
way to live with them
828
00:52:33,860 --> 00:52:35,950
is to live with them consciously.
829
00:52:35,950 --> 00:52:38,580
- Yeah, because you can't change the past.
830
00:52:38,580 --> 00:52:40,990
There's no sense in wanting revenge
831
00:52:40,990 --> 00:52:44,360
or no sense in being really
angry at those events
832
00:52:44,360 --> 00:52:47,774
or other people that
done, but just that sense
833
00:52:47,774 --> 00:52:51,520
of that's who made me who I am,
834
00:52:51,520 --> 00:52:54,533
in part of what made
me who I am, you know,
835
00:52:54,533 --> 00:52:56,005
- it doesn't feel like
there has been some kind
836
00:52:56,005 --> 00:52:56,838
of breakthrough.
837
00:52:56,838 --> 00:52:57,720
- Yeah, it does feel like that
838
00:52:57,720 --> 00:52:59,370
I feel enthusiastic to just go home
839
00:52:59,370 --> 00:53:00,250
and start normal things.
840
00:53:00,250 --> 00:53:02,347
You know, It's like a
just a desire to get up
841
00:53:02,347 --> 00:53:03,830
and get going, though,
you know, after going
842
00:53:24,830 --> 00:53:27,950
- John, Maggie and that children
are sharing a single room
843
00:53:27,950 --> 00:53:30,340
in a hotel while their
home is being renovated
844
00:53:30,340 --> 00:53:31,461
after the flood.
845
00:53:31,461 --> 00:53:36,311
- Yeah.
846
00:53:36,311 --> 00:53:37,839
That's fine.
847
00:53:37,839 --> 00:53:42,839
- Thank you.
848
00:53:47,630 --> 00:53:51,320
It's got a motion sensor so
it just keeps flying itself
849
00:53:51,320 --> 00:53:54,713
if you weren't there was
Chewbacca. You're late.
850
00:53:59,063 --> 00:53:59,896
Let me wait.
851
00:54:15,396 --> 00:54:20,396
The main imagery
852
00:54:27,933 --> 00:54:29,920
firstly we come up here they
will not believe us ahead
853
00:54:29,920 --> 00:54:33,650
of us, you know I have
a dog with a dog. Yeah
854
00:54:37,900 --> 00:54:39,033
a long time ago.
855
00:55:13,856 --> 00:55:15,787
Lessons efficient got bad.
856
00:55:15,787 --> 00:55:17,970
And if he was nice, he
was good for laughing
857
00:55:17,970 --> 00:55:19,070
I think it feels good.
858
00:55:21,531 --> 00:55:22,593
Not normal anymore.
859
00:55:24,210 --> 00:55:27,123
Yeah, but weird sounds negative.
860
00:55:28,040 --> 00:55:29,376
You mean that you don't know.
861
00:55:29,376 --> 00:55:30,209
It's weird.
862
00:55:30,209 --> 00:55:34,110
It's just binge having john
here because I've been used to
863
00:55:35,725 --> 00:55:37,463
live on my own for so long.
864
00:56:05,215 --> 00:56:07,280
- Apparently that if you take
the full month more from me
865
00:56:07,280 --> 00:56:09,330
die within six days, no, you don't
866
00:56:11,599 --> 00:56:12,970
- Think that you do need to remember
867
00:56:12,970 --> 00:56:15,120
that are some dangerous
mushrooms are just like it.
868
00:56:15,120 --> 00:56:16,770
So it's not a good idea to agree.
869
00:56:18,140 --> 00:56:19,780
The reason it works is
because it's about you,
870
00:56:19,780 --> 00:56:23,910
but in sort of like
along here in the middle,
871
00:56:23,910 --> 00:56:25,810
and then suddenly with depression that
872
00:56:27,050 --> 00:56:29,670
it sort of becomes really bogged down
873
00:56:29,670 --> 00:56:31,867
or negative things all the time.
874
00:56:31,867 --> 00:56:34,697
And so what that does is
it it kind of shifts all up
875
00:56:34,697 --> 00:56:36,777
and then lets it resettle
in a different way.
876
00:56:36,777 --> 00:56:40,100
But the first it felt quite nice.
877
00:56:40,100 --> 00:56:41,070
The second time when I took it,
878
00:56:41,070 --> 00:56:42,370
it was a much higher dose.
879
00:56:43,627 --> 00:56:44,830
And it was the most horrible thing
880
00:56:44,830 --> 00:56:46,180
that I've ever experienced.
881
00:56:47,020 --> 00:56:50,580
Might an anemia that lasts for
six hours and doesn't stop.
882
00:56:50,580 --> 00:56:52,095
- Yeah, that's okay.
883
00:56:52,095 --> 00:56:55,630
- And that's that's a
danger if you just to say
884
00:56:55,630 --> 00:56:57,360
do you want to take it for fun?
885
00:56:57,360 --> 00:56:58,193
You don't know.
886
00:56:58,193 --> 00:57:00,380
I was lucky that I had Dr. Joe Novotny,
887
00:57:00,380 --> 00:57:02,523
who could make sure nothing bad happened.
888
00:57:16,170 --> 00:57:18,690
- Before the treatment,
yeah, we did have a Dad.
889
00:57:18,690 --> 00:57:20,840
But if we did see him, it
wouldn't be for very long
890
00:57:20,840 --> 00:57:21,930
for like five to 10 minutes
891
00:57:21,930 --> 00:57:23,930
and you'd have to go back into his room
892
00:57:23,930 --> 00:57:25,850
because you'd have a sore head.
893
00:57:25,850 --> 00:57:28,600
Since the treatment,
she's got much happier.
894
00:57:28,600 --> 00:57:30,900
And, but we all have to be honest.
895
00:57:30,900 --> 00:57:33,810
And she's managed to spend
time with her husband
896
00:57:33,810 --> 00:57:36,020
like we've gone to sleep
overs and I've gone sleepovers
897
00:57:36,020 --> 00:57:37,700
and it's been mom and dad.
898
00:57:37,700 --> 00:57:39,700
They've been having movie nights.
899
00:57:39,700 --> 00:57:41,380
They've been sitting on the couch,
900
00:57:41,380 --> 00:57:43,980
they've had a couch eat
falling asleep on the couch,
901
00:57:44,860 --> 00:57:47,700
doing things that they used
to do before they had kids
902
00:57:47,700 --> 00:57:49,690
before dad had depression.
903
00:57:49,690 --> 00:57:50,980
That's new my dad started
904
00:57:50,980 --> 00:57:55,980
and not the grumpy old fart in the corner.
905
00:58:00,400 --> 00:58:01,960
- Six months after the trial,
906
00:58:01,960 --> 00:58:04,103
the results are presented to the media
907
00:58:04,103 --> 00:58:07,354
- Ctrl S control is set up a file control
908
00:58:07,354 --> 00:58:09,743
as every time you change it.
909
00:58:09,743 --> 00:58:11,493
Usually fine. It's the last minute.
910
00:58:13,812 --> 00:58:17,527
This is a celebration as well
as it is taken four years,
911
00:58:19,023 --> 00:58:21,450
yeah, four years here.
912
00:58:21,450 --> 00:58:23,370
Three of those years
were kind of unnecessary.
913
00:58:23,370 --> 00:58:26,670
They're just plowing
through regulatory hurdles,
914
00:58:26,670 --> 00:58:27,503
but we did it.
915
00:58:27,503 --> 00:58:30,210
- And so how important is today then?
916
00:58:30,210 --> 00:58:31,540
- Today's the birth of a new era
917
00:58:31,540 --> 00:58:33,920
in the treatment of depression.
918
00:58:33,920 --> 00:58:37,710
- It's the first depression
trial with a psychedelic drug.
919
00:58:37,710 --> 00:58:40,133
So it is it's landmark stuff.
920
00:58:41,300 --> 00:58:42,720
Nice morning, everyone.
921
00:58:42,720 --> 00:58:46,570
Welcome to the SMC for
some mornings briefing,
922
00:58:46,570 --> 00:58:49,980
and psilocybin an option for
treatment resistant depression,
923
00:58:49,980 --> 00:58:54,040
and to be published in last
psychiatry embargo is 10:30pm.
924
00:58:54,040 --> 00:58:55,000
Tomorrow.
925
00:58:55,000 --> 00:58:58,180
- The average duration of
the illness in this sample
926
00:58:58,180 --> 00:59:01,370
was 18 years so many of
the patients have had
927
00:59:01,370 --> 00:59:05,050
Depression fractionally most
of their adult lives, yet,
928
00:59:05,050 --> 00:59:07,870
eight of the 12 were
essentially depression free,
929
00:59:07,870 --> 00:59:11,240
one week post treatment and
five remain depression free.
930
00:59:11,240 --> 00:59:12,810
Three months post treatment,
931
00:59:12,810 --> 00:59:14,910
you can see some relapse
in some of the patients.
932
00:59:14,910 --> 00:59:16,340
So let's not get carried away.
933
00:59:16,340 --> 00:59:17,730
This isn't a magic cure.
934
00:59:17,730 --> 00:59:21,703
Even so, the effects at this
stage, things look promising.
935
00:59:23,040 --> 00:59:24,790
- How would you envisage this thing goes?
936
00:59:24,790 --> 00:59:27,060
Would it be kind of a one off treatment?
937
00:59:27,060 --> 00:59:28,330
Or would it be repeated?
938
00:59:28,330 --> 00:59:29,940
- I think that's what we need to find out.
939
00:59:29,940 --> 00:59:31,500
The key question is what
to do with the people
940
00:59:31,500 --> 00:59:33,100
who got an initial benefit,
941
00:59:33,100 --> 00:59:34,760
and then it starts to wane.
942
00:59:34,760 --> 00:59:36,460
So we're thinking about trying to set up
943
00:59:36,460 --> 00:59:39,360
what you might call a
more naturalistic study.
944
00:59:39,360 --> 00:59:40,700
So perhaps that those people
945
00:59:40,700 --> 00:59:43,285
could then be redosed every three months.
946
00:59:43,285 --> 00:59:45,430
And just see if that if
the effect came back.
947
00:59:45,430 --> 00:59:48,210
I mean, it might it might
not depressed people
948
00:59:48,210 --> 00:59:49,200
have a view of the world,
949
00:59:49,200 --> 00:59:52,850
which is that the world
is a nasty, hostile place.
950
00:59:52,850 --> 00:59:56,060
And of course, they're
right, because it is,
951
00:59:56,060 --> 00:59:57,180
but after psilocybin,
952
00:59:57,180 --> 00:59:59,490
the progress people tend to
view the world the same way
953
00:59:59,490 --> 01:00:01,190
in 3D which is is better
954
01:00:01,190 --> 01:00:03,173
than it is and that's a great defense.
955
01:00:12,800 --> 01:00:14,160
- What would be the process
956
01:00:14,160 --> 01:00:15,500
for a drug like psilocybin
957
01:00:15,500 --> 01:00:17,600
to move from schedule one to schedule two?
958
01:00:17,600 --> 01:00:19,750
What are the sort of reasons
that it isn't happening?
959
01:00:19,750 --> 01:00:22,770
- Yeah, I would say a major reason is
960
01:00:22,770 --> 01:00:26,860
because of the United Nations
conventions and the scheduled.
961
01:00:26,860 --> 01:00:28,663
Under those conventions,
962
01:00:29,540 --> 01:00:33,330
that country like the UK tends to follow,
963
01:00:33,330 --> 01:00:38,190
and that those conventions very
clearly includes psilocybin
964
01:00:38,190 --> 01:00:40,100
within schedule one.
965
01:00:40,100 --> 01:00:43,630
So to move against the UN conventions,
966
01:00:43,630 --> 01:00:46,370
you really need some strong evidence.
967
01:00:46,370 --> 01:00:48,800
So it's a sort of chicken
and egg situation,
968
01:00:48,800 --> 01:00:52,350
if psilocybin will put
into scheduled to this
969
01:00:52,350 --> 01:00:54,450
would make it much easier for researchers
970
01:00:54,450 --> 01:00:56,690
to get hold of it to get a license.
971
01:00:56,690 --> 01:00:58,900
You know, the whole
thing would be freed up
972
01:00:58,900 --> 01:01:01,400
then have lots of research and
973
01:01:01,400 --> 01:01:05,350
And if it shows that
psilocybin really help people
974
01:01:05,350 --> 01:01:06,980
with depression, you'd get changed
975
01:01:06,980 --> 01:01:09,350
but getting that research to happen,
976
01:01:09,350 --> 01:01:11,983
while is Johnson's shadow,
it's very difficult.
977
01:01:32,220 --> 01:01:34,670
- Do you have any regrets
about during the trial?
978
01:01:37,510 --> 01:01:42,510
- I suppose really only in
the audit revealed to me,
979
01:01:43,680 --> 01:01:45,193
I think with a high dose.
980
01:01:48,000 --> 01:01:53,000
The experiences were were
profound and pretty dark.
981
01:01:54,470 --> 01:01:57,480
It introduced me to the flag, but
982
01:01:59,480 --> 01:02:01,240
it's something really
nasty could have happened.
983
01:02:01,240 --> 01:02:04,160
Did my childhood and
984
01:02:05,180 --> 01:02:08,380
you can't kind of think that
985
01:02:09,660 --> 01:02:14,603
but it kind of leaves you
with the feeling of well,
986
01:02:16,370 --> 01:02:20,630
was that a case did it, you
know, was I was I smothered
987
01:02:21,690 --> 01:02:25,320
as an infant, there's two sides
of spades that is that well,
988
01:02:25,320 --> 01:02:30,320
if I'd not learn that, then
maybe the recovery process
989
01:02:32,940 --> 01:02:35,913
wouldn't be working hasn't worked.
990
01:02:37,230 --> 01:02:42,230
Or does nothing It actually
make the whole situation worse.
991
01:02:43,970 --> 01:02:44,803
But yeah, I do it again.
992
01:02:44,803 --> 01:02:47,580
You know, it's, it introduces you to
993
01:02:49,230 --> 01:02:52,713
a possible solution for depression.
994
01:02:53,820 --> 01:02:55,693
It was a little bit empowering.
995
01:02:58,240 --> 01:03:03,240
It made me well perhaps I'm
not just like a passenger
996
01:03:04,610 --> 01:03:08,000
on this that he you know, merry go round.
997
01:03:08,000 --> 01:03:10,650
It might be that I can
actually do something about it
998
01:03:18,200 --> 01:03:23,200
could be a whole new way of
accessing the the subconscious,
999
01:03:29,350 --> 01:03:31,603
the psyche, whatever, whatever it is.
1000
01:03:54,380 --> 01:03:59,380
John is pretty much like it
was before the trial is crap.
1001
01:04:00,140 --> 01:04:05,140
put it bluntly hoped
the results on the trial
1002
01:04:06,390 --> 01:04:07,400
would last forever.
1003
01:04:07,400 --> 01:04:10,710
Because it was, it was so
nice because at the back
1004
01:04:10,710 --> 01:04:13,940
and to a certain extent
are my husband back
1005
01:04:13,940 --> 01:04:16,500
and it's gone again.
1006
01:04:16,500 --> 01:04:18,343
It's just, it's all gone.
1007
01:04:23,210 --> 01:04:26,790
That's my favorite one
ever just all together.
1008
01:04:26,790 --> 01:04:28,846
It was really nice.
1009
01:04:28,846 --> 01:04:30,690
It was a fifth of March.
1010
01:04:30,690 --> 01:04:33,660
And we've not been out
for a walk together since
1011
01:04:37,310 --> 01:04:38,360
which is kind of sad.
1012
01:04:57,942 --> 01:04:59,764
If you could write your
own and to be honest,
1013
01:04:59,764 --> 01:05:01,473
I know Robin said that the new way
1014
01:05:01,473 --> 01:05:03,750
He's went back as bad
as they were before but
1015
01:05:05,891 --> 01:05:07,420
I don't think it would take much longer
1016
01:05:07,420 --> 01:05:08,870
before I was back here it was
1017
01:05:10,230 --> 01:05:12,620
the darkness gradually came back.
1018
01:05:12,620 --> 01:05:14,770
The self loathing comes back,
1019
01:05:14,770 --> 01:05:19,140
the desire to be cut off
from the world comes back.
1020
01:05:19,140 --> 01:05:21,990
Then what happens is he gets
compounded you feel guilty
1021
01:05:21,990 --> 01:05:23,770
that you are like that.
1022
01:05:23,770 --> 01:05:25,200
Then you feel guilty that your family
1023
01:05:25,200 --> 01:05:26,550
have to suffer through that
1024
01:05:28,470 --> 01:05:31,293
measure he doesn't like to
have enjoyable surroundings.
1025
01:05:33,760 --> 01:05:37,860
Somebody in a mentally I say
living in a tenement flat
1026
01:05:37,860 --> 01:05:39,883
may think Mrs. Potter days I'll do that.
1027
01:05:41,340 --> 01:05:43,890
The only thing I want is as a room
1028
01:05:43,890 --> 01:05:45,883
where no windows and a door.
1029
01:05:46,940 --> 01:05:48,070
You know what, we're
just going to shut out
1030
01:05:48,070 --> 01:05:49,820
and spend the rest your life there.
1031
01:05:54,111 --> 01:05:56,204
You're a good boy.
1032
01:06:20,660 --> 01:06:22,183
So, 7.5.
1033
01:06:25,368 --> 01:06:28,483
That's for take a night sleeping.
1034
01:06:29,519 --> 01:06:30,530
Suppose Pan 10s.
1035
01:06:30,530 --> 01:06:32,600
These are for sleeping.
1036
01:06:32,600 --> 01:06:34,790
When I don't take us up,
learn take one of those.
1037
01:06:34,790 --> 01:06:35,633
Vice versa.
1038
01:06:37,110 --> 01:06:39,910
This is Friday four hundreds.
1039
01:06:39,910 --> 01:06:42,130
We'll take two of those at night.
1040
01:06:42,130 --> 01:06:46,320
That's lithium. This is a
mood stabilizer apparently.
1041
01:06:46,320 --> 01:06:49,267
So maybe people with bipolar disorder,
1042
01:06:49,267 --> 01:06:53,390
take that, loperamide help stop diarrhea.
1043
01:06:53,390 --> 01:06:56,380
So I take about eight of those a day.
1044
01:06:56,380 --> 01:06:59,050
- Did you have that because
of the drugs you're taking?
1045
01:06:59,050 --> 01:07:02,740
- Yeah, possibly duloxetine 60 mils,
1046
01:07:02,740 --> 01:07:05,990
this is an antidepressant
and 15 by
1047
01:07:05,990 --> 01:07:08,400
take two of these, I take 30 you know,
1048
01:07:08,400 --> 01:07:09,480
I want to get better,
1049
01:07:09,480 --> 01:07:13,360
I want to feel better I
want to give to society,
1050
01:07:13,360 --> 01:07:15,230
I want to be part of society.
1051
01:07:15,230 --> 01:07:17,790
You know, understand I've got a problem,
1052
01:07:17,790 --> 01:07:20,340
and I've had it for a long
time and it's just like,
1053
01:07:21,260 --> 01:07:23,310
you live you live daily, and
1054
01:07:28,420 --> 01:07:32,313
yeah, try and hide yourself
away as much as possible.
1055
01:07:55,580 --> 01:07:57,290
- Two years after the trial,
1056
01:07:57,290 --> 01:08:00,370
Ros has arranged for additional
reintegration therapy
1057
01:08:00,370 --> 01:08:02,440
for Andy to make sense
of some of the visions
1058
01:08:02,440 --> 01:08:07,440
he had during his high dose
was just locked into this farm
1059
01:08:07,567 --> 01:08:11,700
- Trying to expose me
when I was an infant.
1060
01:08:11,700 --> 01:08:13,115
And yeah, great.
1061
01:08:13,115 --> 01:08:15,440
That's why I've been depressed in my life.
1062
01:08:15,440 --> 01:08:18,800
So it was kind of convenient for me
1063
01:08:18,800 --> 01:08:21,410
to be able to blame my depression on that.
1064
01:08:22,860 --> 01:08:25,760
But in reality, I think
that was quite simplistic,
1065
01:08:25,760 --> 01:08:27,387
and I think you helped me,
1066
01:08:27,387 --> 01:08:31,040
but you helped me almost
turn that on its head.
1067
01:08:31,040 --> 01:08:33,960
You've introduced a rationale
1068
01:08:33,960 --> 01:08:36,660
that I can view the whole experience
1069
01:08:36,660 --> 01:08:39,000
when you pair of eyes and you know,
1070
01:08:39,000 --> 01:08:42,780
the chances of dad actually
doing that pretty remote.
1071
01:08:42,780 --> 01:08:44,540
It doesn't stack out with anything
1072
01:08:44,540 --> 01:08:46,750
because it would have been something
1073
01:08:46,750 --> 01:08:48,940
that mom would have written in a memoirs
1074
01:08:48,940 --> 01:08:51,670
which is what I've got,
you know, she would,
1075
01:08:51,670 --> 01:08:53,730
she would definitely
written something there
1076
01:08:53,730 --> 01:08:56,163
that do you realize your dad did this?
1077
01:08:58,320 --> 01:09:01,360
It's really, really good
because I'm not thinking
1078
01:09:01,360 --> 01:09:02,850
Was he dead?
1079
01:09:02,850 --> 01:09:04,720
Wasn't it and you know if it was to him,
1080
01:09:04,720 --> 01:09:08,040
or did he do it because I thought
he loved me kind of thing?
1081
01:09:08,040 --> 01:09:13,040
That's that thought bloopers is gone.
1082
01:09:13,340 --> 01:09:16,800
I can't thank you enough
for what you've done.
1083
01:09:16,800 --> 01:09:19,010
It has been pretty much life changing.
1084
01:09:19,010 --> 01:09:21,753
So, you know, really, really?
1085
01:09:24,290 --> 01:09:26,183
- Thank you very much. Okay.
1086
01:09:31,583 --> 01:09:32,877
- How was that?
1087
01:09:32,877 --> 01:09:35,280
- It was good. Yeah, I think
1088
01:09:36,940 --> 01:09:41,850
it was a good summary of what
Andrew has been going through,
1089
01:09:41,850 --> 01:09:42,870
but also a good example
1090
01:09:42,870 --> 01:09:44,710
of how this integration process works.
1091
01:09:44,710 --> 01:09:46,120
- In terms of the smothering,
1092
01:09:46,120 --> 01:09:48,960
do you think that he would
experience it all differently?
1093
01:09:48,960 --> 01:09:52,020
- Now, I think that the
one of the key aspects
1094
01:09:52,020 --> 01:09:54,500
of the integration process with Andrew was
1095
01:09:54,500 --> 01:09:57,980
to take some of the pressure out of having
1096
01:09:57,980 --> 01:10:01,290
to find the definite enter
of was it through memory or
1097
01:10:01,290 --> 01:10:03,670
Is it something that I
in my mind just made that
1098
01:10:03,670 --> 01:10:04,970
in the event itself,
1099
01:10:04,970 --> 01:10:07,690
what he saw is not that his
father was smothering him
1100
01:10:07,690 --> 01:10:11,340
is that actually became a
symbolical representation
1101
01:10:11,340 --> 01:10:14,500
of his whole childhood in which it looked
1102
01:10:14,500 --> 01:10:17,830
like his mother was trying
to present his father
1103
01:10:17,830 --> 01:10:19,083
as a bad figure.
1104
01:10:24,040 --> 01:10:26,530
- There were three parts
to Andy's high day session.
1105
01:10:26,530 --> 01:10:29,150
The first was about feeling unwanted
1106
01:10:29,150 --> 01:10:30,550
by his father as a baby.
1107
01:10:30,550 --> 01:10:32,580
The second was about feeling criticized
1108
01:10:32,580 --> 01:10:34,650
and controlled by his mother as a child.
1109
01:10:34,650 --> 01:10:37,270
And the third was more
about healthy adult position
1110
01:10:37,270 --> 01:10:40,130
of feeling, compassion
and love and acceptance
1111
01:10:40,130 --> 01:10:41,103
and understanding.
1112
01:10:44,890 --> 01:10:45,970
After the high day session,
1113
01:10:45,970 --> 01:10:49,910
Andy went back to that early
place of wounding feeling
1114
01:10:49,910 --> 01:10:51,840
unwanted by his father.
1115
01:10:51,840 --> 01:10:53,910
He then with marks helping integration
1116
01:10:53,910 --> 01:10:55,310
has been able to progress forward
1117
01:10:55,310 --> 01:10:57,590
and stop focusing more on his
feelings around his mother
1118
01:10:57,590 --> 01:11:00,720
in the criticism and
control of his childhood.
1119
01:11:00,720 --> 01:11:03,100
We hope with a bit of time and will work,
1120
01:11:03,100 --> 01:11:04,710
you'll be able to progress forward
1121
01:11:04,710 --> 01:11:06,410
to that third stage he did experience
1122
01:11:06,410 --> 01:11:10,110
which was more about the
acceptance and love for himself
1123
01:11:10,110 --> 01:11:11,473
and for his parents.
1124
01:11:14,540 --> 01:11:16,530
The wonderful thing about
this treatment is that
1125
01:11:16,530 --> 01:11:18,020
it's able to take you on this journey
1126
01:11:18,020 --> 01:11:19,870
in the space of a day actually
1127
01:11:19,870 --> 01:11:21,130
with the integration afterwards
1128
01:11:21,130 --> 01:11:23,330
whereas antidepressants
could never do that.
1129
01:11:24,340 --> 01:11:26,140
Antidepressants don't give you any insight
1130
01:11:26,140 --> 01:11:27,680
as to why you're depressed.
1131
01:11:27,680 --> 01:11:29,020
And once you knew why you're depressed,
1132
01:11:29,020 --> 01:11:31,020
you know what it is inside,
1133
01:11:31,020 --> 01:11:32,860
then there's a possibility
of processing it
1134
01:11:32,860 --> 01:11:34,860
and actually potentially getting better.
1135
01:11:37,920 --> 01:11:40,720
- Psychedelic therapy is
not pharmacological therapy
1136
01:11:40,720 --> 01:11:41,610
is not that we're going
to have an experience
1137
01:11:41,610 --> 01:11:44,000
and then that aggression
is going to be gone.
1138
01:11:44,000 --> 01:11:46,260
The task of breaching what we learned
1139
01:11:46,260 --> 01:11:48,260
in the psychedelic experience into changes
1140
01:11:48,260 --> 01:11:50,450
that actually have an
influence in our physical
1141
01:11:50,450 --> 01:11:51,560
and daily life.
1142
01:11:51,560 --> 01:11:54,890
That is the part that it's
for me extremely important
1143
01:11:54,890 --> 01:11:55,723
and how to do that.
1144
01:11:55,723 --> 01:11:57,920
It's something that we
still don't really know.
1145
01:11:57,920 --> 01:11:59,310
And I think that is where the challenge
1146
01:11:59,310 --> 01:12:01,803
for the next two years come.
1147
01:12:14,110 --> 01:12:15,849
- Sort of out of it.
1148
01:12:15,849 --> 01:12:19,873
How do you feel glad it's
done slightly exhausted,
1149
01:12:20,810 --> 01:12:23,402
pleased it went so well.
1150
01:12:23,402 --> 01:12:27,140
On the other hand, a little
frustrated that the fact
1151
01:12:27,140 --> 01:12:29,320
that we can't deliver this treatment,
1152
01:12:29,320 --> 01:12:30,917
you know when people need it
1153
01:12:30,917 --> 01:12:33,310
and just being here in central London
1154
01:12:33,310 --> 01:12:35,300
and being so busy,
1155
01:12:35,300 --> 01:12:37,890
they say one in 10 people are
suffering from depression.
1156
01:12:37,890 --> 01:12:41,120
That's likely a few people
around us right now.
1157
01:12:41,120 --> 01:12:42,290
It's a massive problem.
1158
01:12:42,290 --> 01:12:44,307
- So what are the results?
1159
01:12:44,307 --> 01:12:47,840
- Andy, Mark and john
Andy and john showed quite
1160
01:12:47,840 --> 01:12:50,960
a good initial response, especially john,
1161
01:12:50,960 --> 01:12:53,270
but then they did back So on average,
1162
01:12:53,270 --> 01:12:55,270
they were the best responders.
1163
01:12:55,270 --> 01:12:57,560
But if you take the whole
group at three weeks,
1164
01:12:57,560 --> 01:12:59,070
roughly half were in remission,
1165
01:12:59,070 --> 01:13:01,120
meaning essentially their depression free
1166
01:13:01,120 --> 01:13:05,103
After on average, about
18 years of depression,
1167
01:13:06,140 --> 01:13:09,010
six months six, still depression free.
1168
01:13:09,010 --> 01:13:11,250
So it's quite promising really.
1169
01:13:11,250 --> 01:13:13,100
And now they're only depression free sort
1170
01:13:13,100 --> 01:13:14,410
of two years later.
1171
01:13:14,410 --> 01:13:16,770
Yeah, yeah, there are. Yeah.
1172
01:13:16,770 --> 01:13:19,310
So people's lives have
just been transformed.
1173
01:13:19,310 --> 01:13:22,120
It suggests the treatment
seems to work at least
1174
01:13:22,120 --> 01:13:24,350
as well as conventional treatments.
1175
01:13:24,350 --> 01:13:26,190
What we want to do next is compare it
1176
01:13:26,190 --> 01:13:27,630
against conventional treatments.
1177
01:13:27,630 --> 01:13:30,710
We need bigger trials, more
rigorously designed trials,
1178
01:13:30,710 --> 01:13:33,410
double blind randomized control trials.
1179
01:13:33,410 --> 01:13:35,310
Unfortunately, that's happening now.
1180
01:13:35,310 --> 01:13:39,370
So a few teams around the world
are running these studies,
1181
01:13:39,370 --> 01:13:42,340
major investments coming
in as a multi site trial
1182
01:13:42,340 --> 01:13:45,060
across Europe, and the US and Canada.
1183
01:13:45,060 --> 01:13:46,430
15 different countries.
1184
01:13:46,430 --> 01:13:50,520
So for things to be expanding to the scale
1185
01:13:50,520 --> 01:13:52,893
that they are right
now is really exciting.
1186
01:14:03,160 --> 01:14:04,673
- It's definitely one.
1187
01:14:10,970 --> 01:14:13,650
Speaking to guys on the trial afterwards,
1188
01:14:13,650 --> 01:14:16,120
I said, Yeah, probably if
you'd had a stronger dose
1189
01:14:16,120 --> 01:14:20,000
or a third dose, you would
have had, a breakthrough.
1190
01:14:20,000 --> 01:14:23,190
But I don't know if I can
risk going picking a load
1191
01:14:23,190 --> 01:14:25,570
of these and sitting in my bedroom
1192
01:14:27,290 --> 01:14:31,240
tripping my nuts off and
going, I've got no support.
1193
01:14:31,240 --> 01:14:33,413
I don't you know, I
don't know what to do in.
1194
01:14:34,460 --> 01:14:35,810
I did feel as though I failed.
1195
01:14:35,810 --> 01:14:38,670
I failed the test. Did it not work at all?
1196
01:14:38,670 --> 01:14:39,503
I mean, obviously,
1197
01:14:39,503 --> 01:14:42,460
I experienced a major
amount of weirdness but
1198
01:14:45,470 --> 01:14:47,880
it opened up a lot of questions about my
1199
01:14:50,419 --> 01:14:52,563
like my illness, but it never,
1200
01:14:54,399 --> 01:14:59,250
never really kind of pointed
me in the right direction
1201
01:14:59,250 --> 01:15:00,330
have any answers?
1202
01:15:00,330 --> 01:15:02,010
And maybe there aren't any answers.
1203
01:15:02,010 --> 01:15:04,243
And that's just something I got deal with.
1204
01:15:30,570 --> 01:15:33,339
- Has that been in the
last couple of months?
1205
01:15:33,339 --> 01:15:35,510
- Well, in the past couple
of months has not been
1206
01:15:35,510 --> 01:15:36,680
as good as it was before,
1207
01:15:36,680 --> 01:15:41,583
but is still the same person as he was
1208
01:15:43,510 --> 01:15:45,628
four or five years before.
1209
01:15:45,628 --> 01:15:49,663
And we just saw that same
person again, a few months back.
1210
01:15:50,510 --> 01:15:55,510
So it was nice that they would do again,
1211
01:15:56,670 --> 01:15:59,570
it would be nice to have
1212
01:15:59,570 --> 01:16:01,400
- Do you believe in psilocybin?
1213
01:16:01,400 --> 01:16:02,420
- Oh yeah, because
1214
01:16:04,000 --> 01:16:08,510
I've seen what was done and
it will make a miracle really
1215
01:16:09,750 --> 01:16:12,210
we never thought it would be like again
1216
01:16:12,210 --> 01:16:16,970
and then he took the
trial and it was great.
1217
01:16:16,970 --> 01:16:21,970
Yeah, was was really good.
1218
01:16:23,437 --> 01:16:25,063
- A few months after the
trial that was really good
1219
01:16:25,063 --> 01:16:27,020
and it was really good to see him happy
1220
01:16:27,020 --> 01:16:28,580
and the rest of us happy.
1221
01:16:28,580 --> 01:16:30,340
I think it made him feel happy
1222
01:16:30,340 --> 01:16:32,510
that everyone else was happy as well.
1223
01:16:32,510 --> 01:16:33,603
But I don't think it was a bad thing
1224
01:16:33,603 --> 01:16:36,393
that we saw it like it was nice to see it.
1225
01:16:37,400 --> 01:16:39,320
But and their memories
that we're all going
1226
01:16:39,320 --> 01:16:41,333
to keep forever asleep.
1227
01:16:42,450 --> 01:16:44,900
Better seeing those memories
and not having them.
1228
01:16:52,440 --> 01:16:53,361
- Every week
thousands of people
1229
01:16:53,361 --> 01:16:56,770
who could benefit
1230
01:16:56,770 --> 01:16:59,830
from interventions with
these drugs are denied access
1231
01:17:00,860 --> 01:17:04,380
and that means they will
continue with their depressions
1232
01:17:04,380 --> 01:17:05,940
and their addictions.
1233
01:17:05,940 --> 01:17:07,630
That is outrageous it,
1234
01:17:07,630 --> 01:17:11,300
there is no need to limit
access of these drugs
1235
01:17:11,300 --> 01:17:12,467
for medical research.
1236
01:17:12,467 --> 01:17:15,870
But the current regulations
make it almost impossible
1237
01:17:15,870 --> 01:17:17,283
for anyone to use them.
1238
01:17:22,107 --> 01:17:23,720
In some respects is worse than before.
1239
01:17:23,720 --> 01:17:28,720
And we'll some videos that
will help this frustration that
1240
01:17:30,490 --> 01:17:34,590
I can't really take
full advantage of that,
1241
01:17:34,590 --> 01:17:37,060
who's benefited from that level of benefit
1242
01:17:37,060 --> 01:17:38,642
because I'm ,
1243
01:17:38,642 --> 01:17:40,380
my children won't benefit
because I'm not walking
1244
01:17:40,380 --> 01:17:43,380
and showing them what proper
father a proper person
1245
01:17:43,380 --> 01:17:44,870
should be doing with a
life to be a productive
1246
01:17:44,870 --> 01:17:45,890
part of society.
1247
01:17:45,890 --> 01:17:47,210
Other people who need help to
1248
01:17:47,210 --> 01:17:49,330
and benefit because
money's been spent on me
1249
01:17:49,330 --> 01:17:50,630
when I can be back a work.
1250
01:17:54,370 --> 01:17:56,030
- You want me to do the apology
1251
01:17:56,030 --> 01:17:58,627
at the top the bit of golden rules.
92916
Can't find what you're looking for?
Get subtitles in any language from opensubtitles.com, and translate them here.