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good afternoon to all of you thank you
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for joining me today for this important
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topic of prostate health solutions
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backed by research today the topic of
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prostate health and prostate cancer it's
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a huge topic and if I would go in detail
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into what I want to touch on today it
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will take me hours so I will pick a few
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important point share with you some
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important updates on the research that
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I've been involved in for almost 25
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years and now some very important
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studies that just came out you may
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clinical trials but I will try to use
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very simple conditions that in on
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prostate health such as BP age and
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prostate cancer a little bit [ __ ] light
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about the about there about the larger
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context of positive so we can start with
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talking about BPH benign prostatic
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hypertrophy so we discuss contributing
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factors integrative solution and also a
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very important paper that was just
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published that was just published and
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they share share the results and then we
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also talk about prostate cancer a little
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bit about the facts integrative options
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and we'll discuss they're very exciting
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result of modified sit respected a
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multicenter clinical trial in
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biochemical relapse that where i
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presented the results in a scott gu in
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San Francisco in February so I will get
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going
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so BPH is a very common condition it's
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really a physiological condition it's
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something that happens over time in age
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for men and it's a basically a swelling
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of the prostate that puts pressure on
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there on the urethra and as the results
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causes different symptoms urinary
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symptoms pain and sexual dysfunction
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sometimes and the question is what makes
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it to come sooner rather than later and
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how can we prevent it and treat it so
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with
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actually we'll be developing these
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issues from a point of view of
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understanding the prostate is an
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independent organ which is really how
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it's done in Western medicine to really
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understanding what else in the body
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effects the prostate if we can
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understand the health of a certain organ
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from more of a global holistic approach
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this model is what makes the difference
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between an okay treatment and a gray
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treatment
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so again BPH as I mentioned is a very
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common condition you can see about 50
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percent between age 51 and 60 and then
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90 percent when we are older than 80 so
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as we age the prostate grows and swells
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and I won't go into all the mechanisms
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of action mainly because of limitation
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of time you can understand there are so
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many people who are millions of mean
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intensive terms of million of mental
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health issues so when the when the vp8
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pressurizes the urethra it creates what
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we call lots lower urinary tract
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symptoms that include the urinary
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frequency and urgency frequency needing
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to urinate many time urgency we can't
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hold the urine nocturia getting up
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frequently at night to urinate the
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nocturia for example is the factor that
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will affect our quality of life because
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we are not sleeping well in the same
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time stress anxiety emotional issues
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other imbalances that affect our sleep
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will cause us to already get up to pee
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because when we awake we are more
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quickly aware of the need to pee even if
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it's a little bit but an example for
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example about the connection between the
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heart which relates to sleep in Chinese
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medicine and the bladder and interesting
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there are they actually coupled there is
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there is a connection building between
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them and there are certain herbs an
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acupuncture point let's tie into this
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relationship some of the Chinese wisdom
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there is a symptom of hesitancy where
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it's how to start peeing and it's
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interrupted in the stream is weak and
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incomplete bladder emptying which can be
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initially to lead to
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secondary infections straining decreased
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force extreme dribbling and the find
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operations of the points on the wrist
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line prostatic problem that can affect
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ejaculation causing pain in the sexual
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dysfunction but these are symptoms that
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many many men experience in one way or
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another and just for you when you have
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it you want to pay attention what makes
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a difference
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didn't I need a good night's sleep make
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a difference did what you eat in the
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last few days make a difference did if
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you exercise did it make a difference
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and start seeing what affects you one
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thing is know what effect somebody
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statistically but really medicine is a
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medicine in modern medicine as a
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medicine of statistics real medicine
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live medicine is medicine of N equals
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one is what works for each of us that
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matters for each of us so if we look at
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the BP agent we see what contribute to
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BPH and we can go from genetic
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predisposition to hormonal imbalances to
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diet and lifestyle to toxicity to
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metabolic dysfunction to aging and the
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king of everything chronic inflammation
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when we look at this we can really very
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quickly see and understand that the
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prostate is really a reflection of
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multiple health system that can affect
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so many other organs and it is very very
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interesting because classically BPH is
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being treated sometime by your primary
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care but offered by a urologist which is
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very organ and system specific but we
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can see it especially for prostate it's
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unusual how many other systems can
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affect the prostate so I wanna I wanna a
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little bit expand on it in the context
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of BPH but please take these comments
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into prostate cancer which is much more
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critical so the genetic predisposition
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is one thing we can determine these days
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and I'll touch it I'll touch I'll go
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back to it in a moment but I want talk
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about hormonal imbalances and no moral
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imbalances accrued to powers it includes
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the whole Oh
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kornel deficiencies or exercise when you
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test your hormones are too high or too
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low but also how are you breaking down
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your hormones what is happening to your
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hormones when you break them down it's
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very important and this is the place
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where genetic predisposition can affect
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if you have certain mutation certain
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snip pair changes MTHFR etc etc then you
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will get hormones are being processed
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for example in the liver broken up to
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less healthy hormones and in men while
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we focus on testosterone in DHT we have
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to remember that many to age 55 has the
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same level of estrogen sometimes higher
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than women and if we have an inability
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to break our estrogens properly in the
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liver and we have very high f4h
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is to estradiol or high ratio of of 16
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to 2 estradiol and these are unhealthy
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ratios this will increase our chances
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for prostrate heal health issues and
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specifically for prostate cancer but
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also will make the cancer more
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aggressive so when we look at these it's
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just an example but when we visit picked
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hormonal imbalances we're aware that the
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process is stimulated and being enlarged
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by testosterone but especially by
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dehydrogenase customer and when we look
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at the production of behaviour
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testosterone it's very interesting it
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can be produced in the testes on a local
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level it can be converted in the
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prostate it's produced it's significant
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amount by the adrenals it's incense and
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production of the liver the Sun
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production is the brain and there are
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some production in fatty tissues
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depending on different enzymes a 5 alpha
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reductase or aroma change how we are
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shifting the testosterone so you can see
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our multiple system are affecting the
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prostate if we look at atomic Li if I go
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back for a moment and I look
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anatomically at the prostate imagine
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that a bath is a prostate you got your
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whole body right this is like the bottom
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photos which means that everything that
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we have in our body funnels down into
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this area we can often see it in the
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different cancer that we get and I'll
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touch on it toxicity is very important
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for the prostate and we'll talk about it
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more in prostate cancer metabolic
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dysfunction I touched a little bit in
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hormone but I will touch later more in
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aging especially for the pH so the goals
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with me pH is first of all to relieve
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the symptoms of BPH to reduce the lower
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urinary tract symptoms to improve
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quality of life to reduce the prostate
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size and if needed different surgical
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intervention which are we kind becoming
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more and more refined but offer have to
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be repeated so if we look at this as the
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general level of the prostate hill then
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the goal initially in prostate health is
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to address BPH reduce prostate size of
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course there's the whole area of
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prostatitis that can clearly contribute
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to prostate cancer more than BPH but we
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decided not to touch on it today because
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of a issue of time and then of course
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how do we prevent the development of
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positivism and when we look at prostate
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cancer and I'll talk about it in a
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separate ways so we also want to
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understand the prostate cancer is really
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a wide array of serious conditions where
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it can be very physiological or can be
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very aggressive when we look at the
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prevention of development of prostate
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cancer we want to look at restoring your
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hormonal balance which is what I call
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hormonal modulation
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differend and hormonal replacement we
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want to look at improved metabolic
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health very specific metabolic syndrome
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adrenal support and is key ones balance
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between the adrenaline the thyroid and
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the metabolic from the point of view of
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glucose metabolism is critical because
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elevated igf-1 insulin
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because elevated insulin because of
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obesity all of these have an important
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effect of the prostate and um cancers in
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general of the pelvis in both men and
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women one look at tides the Demont
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inflammatory gluten-free low glycemic
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index high protein not fried food and no
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soft wings etc you want to address what
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we ate nutrient deficiencies establish
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regular exercise routine is very
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important there is no better medicine
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than exercise I mean it's remarkable
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when we look at the change in survival
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after initial cancer treatment between
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people who walk regularly and on it's
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50% reduction it's unreal it's a best
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medicine to ever be discovered and
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totally free and within within it we
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want to look at the detoxification of
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heavy metals and environmental toxins
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which will touch on a little bit later
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and stress reduction now it's
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interesting we are showing this on the
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level of prevention of the development
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of prostate cancer but all of these will
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also contribute to be pre agent to
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prostatitis in the package so we can
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have targeted natural compound the
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nutrients to support this process and of
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course we have medication silica and
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other interventions more in this in this
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context today we're gonna focus on the
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pH and of course similar of course for
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00:12:44,539 --> 00:12:54,099
prostate cancer so when we look at the
277
00:12:51,110 --> 00:12:59,149
classical categories for treating the pH
278
00:12:54,100 --> 00:13:02,240
often there is spasm of the of the
279
00:12:59,149 --> 00:13:04,129
muscle of the of the bottom of the
280
00:13:02,240 --> 00:13:06,919
bladder which hasn't let the urine flow
281
00:13:04,129 --> 00:13:09,709
well when the upper part is too relaxed
282
00:13:06,919 --> 00:13:12,708
it doesn't push the urine out and for
283
00:13:09,708 --> 00:13:13,969
this we use alpha blockers there are
284
00:13:12,708 --> 00:13:18,918
different ones
285
00:13:13,970 --> 00:13:21,139
I mean floor mats Hydra dura I mean I've
286
00:13:18,918 --> 00:13:24,889
been around for many years
287
00:13:21,139 --> 00:13:26,749
and they can help relatively quickly the
288
00:13:24,889 --> 00:13:29,269
problem that they have multiple side
289
00:13:26,749 --> 00:13:31,759
effects because you can control the
290
00:13:29,269 --> 00:13:33,639
block the alpha blocker they can reduce
291
00:13:31,759 --> 00:13:35,839
your blood pressure cause dizziness
292
00:13:33,639 --> 00:13:37,850
abnormal ejaculation erectile
293
00:13:35,839 --> 00:13:39,889
dysfunction addict or so static
294
00:13:37,850 --> 00:13:42,889
hypotension that they just mentioned and
295
00:13:39,889 --> 00:13:45,649
fatigue and also study guide potential
296
00:13:42,889 --> 00:13:48,558
can be very significant in the alpha
297
00:13:45,649 --> 00:13:50,539
blockers because the Alpha system is is
298
00:13:48,558 --> 00:13:52,999
the sympathetic system that comes it is
299
00:13:50,539 --> 00:13:56,988
our emergency system our response system
300
00:13:52,999 --> 00:13:59,778
if it's blocked and we get up and now we
301
00:13:56,989 --> 00:14:03,918
leave the blood the pressure to go up
302
00:13:59,778 --> 00:14:06,048
and sustain our circulation that has to
303
00:14:03,918 --> 00:14:08,058
fight gravity now if you don't get a
304
00:14:06,048 --> 00:14:14,328
response you can fade you can feel
305
00:14:08,058 --> 00:14:17,298
light-headed Knesset's it another
306
00:14:14,328 --> 00:14:19,248
category that is very commonly used is
307
00:14:17,298 --> 00:14:21,470
the 5 alpha reductase inhibitors
308
00:14:19,249 --> 00:14:23,058
inhibitors so these are important drug
309
00:14:21,470 --> 00:14:25,910
is that inhibits the movement from
310
00:14:23,058 --> 00:14:30,528
testosterone to dihydrotestosterone they
311
00:14:25,909 --> 00:14:32,118
have an effect on B pH of course and
312
00:14:30,528 --> 00:14:34,489
they also have an important effect in
313
00:14:32,119 --> 00:14:36,949
prostate cancer for people who use
314
00:14:34,489 --> 00:14:38,720
combined hormonal therapy the prostate
315
00:14:36,948 --> 00:14:40,878
cancer has been a movement since the
316
00:14:38,720 --> 00:14:43,129
early 90s and now it's been getting more
317
00:14:40,879 --> 00:14:46,639
and more established you know you use a
318
00:14:43,129 --> 00:14:50,329
in LH our age agonist that stops the
319
00:14:46,639 --> 00:14:55,159
excretion of testosterone like you
320
00:14:50,328 --> 00:14:58,278
pro-lite in an example and then you use
321
00:14:55,159 --> 00:15:00,409
a product that blocks the effect on
322
00:14:58,278 --> 00:15:01,989
there in the confusion on the prostate
323
00:15:00,409 --> 00:15:04,578
like gas or eggs
324
00:15:01,989 --> 00:15:06,589
standee and then i use something that
325
00:15:04,578 --> 00:15:09,288
specifically block the conversion from
326
00:15:06,589 --> 00:15:11,389
testosterone to the hyper distrust the
327
00:15:09,288 --> 00:15:13,428
problem is that when you block it you
328
00:15:11,389 --> 00:15:17,749
have a movement to the other direction
329
00:15:13,428 --> 00:15:19,548
with increased level of estrogens and so
330
00:15:17,749 --> 00:15:22,278
there is some erectile dysfunction not
331
00:15:19,548 --> 00:15:23,838
the same like when you block the
332
00:15:22,278 --> 00:15:26,328
expression of testosterone but a
333
00:15:23,839 --> 00:15:28,699
significant percentage of normal
334
00:15:26,328 --> 00:15:31,099
ejaculation decreased libido depression
335
00:15:28,698 --> 00:15:33,708
anxiety breast enlargement can be severe
336
00:15:31,100 --> 00:15:34,710
for some people and it may increase the
337
00:15:33,708 --> 00:15:37,469
risk of
338
00:15:34,710 --> 00:15:43,410
that cancer especially the work was done
339
00:15:37,470 --> 00:15:46,290
with Bosco so there are some classical
340
00:15:43,409 --> 00:15:49,819
herbs for prostate health that you see
341
00:15:46,289 --> 00:15:53,189
many formulas saw palmetto or by Geum a
342
00:15:49,820 --> 00:15:54,900
pumpkin seed stinging nettle and these
343
00:15:53,190 --> 00:15:58,710
are herbs that have an anti-inflammatory
344
00:15:54,899 --> 00:16:01,829
or monel modulation effects on the
345
00:15:58,710 --> 00:16:06,300
prostate and they will have a benefit in
346
00:16:01,830 --> 00:16:08,250
within a benign Empress in the pH and
347
00:16:06,299 --> 00:16:11,639
also have some benefit in prostitutes
348
00:16:08,250 --> 00:16:13,470
there's some studies showing quercetin
349
00:16:11,639 --> 00:16:17,340
is a remarkable ingredient it's much
350
00:16:13,470 --> 00:16:19,889
bigger than the prostate quercetin is an
351
00:16:17,340 --> 00:16:22,950
anti-inflammatory effect has a
352
00:16:19,889 --> 00:16:26,129
detoxification effect as the regulatory
353
00:16:22,950 --> 00:16:30,120
effects on simple quercetin will prevent
354
00:16:26,129 --> 00:16:32,870
resistance to chemotherapy in different
355
00:16:30,120 --> 00:16:36,990
cancers breast cancer adjacent
356
00:16:32,870 --> 00:16:38,580
quercetin will allow a circulating tumor
357
00:16:36,990 --> 00:16:40,769
cells to become less aggressive
358
00:16:38,580 --> 00:16:43,290
worsening is a very important compound
359
00:16:40,769 --> 00:16:46,590
in the prostate specifically it has an
360
00:16:43,289 --> 00:16:53,819
effect on prostatitis specifically in
361
00:16:46,590 --> 00:16:57,389
someone BPH so if we look at if we look
362
00:16:53,820 --> 00:16:59,760
at how how to really address prostate
363
00:16:57,389 --> 00:17:01,699
health we have all this multiple
364
00:16:59,759 --> 00:17:04,829
category that I showed you a little bit
365
00:17:01,700 --> 00:17:06,809
earlier it has all the categories of
366
00:17:04,829 --> 00:17:10,379
hormonal modulation to addressing
367
00:17:06,809 --> 00:17:13,588
toxicity addressing immunity unless in
368
00:17:10,380 --> 00:17:16,260
circulation addressing inflammation so
369
00:17:13,588 --> 00:17:19,588
this is really the approach that needs
370
00:17:16,259 --> 00:17:21,569
to be taken care of when you go to a
371
00:17:19,588 --> 00:17:24,809
holistic doctor who sees the prostate
372
00:17:21,569 --> 00:17:26,429
bigger than the prostate but there is
373
00:17:24,809 --> 00:17:28,799
also a way to reflect this in
374
00:17:26,430 --> 00:17:31,230
formulation for example in this specific
375
00:17:28,799 --> 00:17:35,369
formula that has multiple published
376
00:17:31,230 --> 00:17:36,990
papers a that's the idea using 33
377
00:17:35,369 --> 00:17:39,209
different ingredients to address the
378
00:17:36,990 --> 00:17:40,980
different categories now the
379
00:17:39,210 --> 00:17:42,720
presentation not specifically on this
380
00:17:40,980 --> 00:17:44,789
formula but if you look at such a
381
00:17:42,720 --> 00:17:47,910
formula we see how the different organs
382
00:17:44,789 --> 00:17:48,690
which address an issue our address space
383
00:17:47,910 --> 00:17:51,869
by
384
00:17:48,690 --> 00:17:54,659
by different ingredients so the study of
385
00:17:51,868 --> 00:17:59,298
the prostate health supplements if it
386
00:17:54,659 --> 00:18:02,278
was a retrospective study on 65 men
387
00:17:59,298 --> 00:18:05,940
evaluating their change in lower urinary
388
00:18:02,278 --> 00:18:09,269
tract symptoms 65 men 20 with prostate
389
00:18:05,940 --> 00:18:11,849
cancer 13 with pph to anyone who is
390
00:18:09,269 --> 00:18:12,558
multiple diagnosis meaning vpa prostate
391
00:18:11,848 --> 00:18:15,509
cancer
392
00:18:12,558 --> 00:18:18,148
Titus maybe and 11 with no formal
393
00:18:15,509 --> 00:18:20,339
diagnosis but this specific formula for
394
00:18:18,148 --> 00:18:21,358
most serious conditions you go up to 12
395
00:18:20,339 --> 00:18:24,348
capsules a day
396
00:18:21,358 --> 00:18:28,259
but interesting some of the subjects to
397
00:18:24,348 --> 00:18:30,358
address just during urinary issues used
398
00:18:28,259 --> 00:18:33,960
only two capsules a day was unusual
399
00:18:30,358 --> 00:18:37,079
literally two twice a day and still we
400
00:18:33,960 --> 00:18:39,058
gained benefits and at least two months
401
00:18:37,079 --> 00:18:40,618
was the inclusion criteria but most of
402
00:18:39,058 --> 00:18:42,928
the people on this study had been using
403
00:18:40,618 --> 00:18:45,509
this for years so we are seeing a
404
00:18:42,929 --> 00:18:47,460
long-term benefit it's something
405
00:18:45,509 --> 00:18:49,798
important when you design a formula in a
406
00:18:47,460 --> 00:18:52,288
synergistic way you don't lose the
407
00:18:49,798 --> 00:18:54,388
benefits over time compared to a drug
408
00:18:52,288 --> 00:18:57,538
where you often get tolerance so that's
409
00:18:54,388 --> 00:19:00,418
another very unique feature of natural
410
00:18:57,538 --> 00:19:03,509
holistic approach that is important to
411
00:19:00,419 --> 00:19:05,429
recognize so when we looked at the
412
00:19:03,509 --> 00:19:07,649
improvement in symptoms based on
413
00:19:05,429 --> 00:19:09,690
questionnaires giving to the 65 subject
414
00:19:07,648 --> 00:19:11,638
we saw sixty point seven percent
415
00:19:09,690 --> 00:19:14,570
improving staining is to understand
416
00:19:11,638 --> 00:19:17,069
about 44 percent in intermittency
417
00:19:14,569 --> 00:19:20,720
similar effect in with improvement of
418
00:19:17,069 --> 00:19:23,038
extreme incomplete emptying and then
419
00:19:20,720 --> 00:19:26,519
significant improvement in or urgency
420
00:19:23,038 --> 00:19:29,638
knocked or and frequency and although
421
00:19:26,519 --> 00:19:33,089
the percentage was four for urgency may
422
00:19:29,638 --> 00:19:35,278
look lower compared to two what the
423
00:19:33,089 --> 00:19:40,168
placebo or does it actually was very
424
00:19:35,278 --> 00:19:42,509
significant so we understand that benign
425
00:19:40,169 --> 00:19:44,609
prostatic health is universal is a
426
00:19:42,509 --> 00:19:47,159
significant impact on quality of life
427
00:19:44,608 --> 00:19:49,769
but it does not sweat in your life it
428
00:19:47,159 --> 00:19:52,169
does not lead directly to prostate
429
00:19:49,769 --> 00:19:55,278
cancer but we really have to be
430
00:19:52,169 --> 00:19:58,729
concerned about and be aware of his
431
00:19:55,278 --> 00:19:58,729
prostate cancer
432
00:19:58,769 --> 00:20:05,049
and prostate cancer is the second most
433
00:20:01,180 --> 00:20:08,440
common cancer in men and the other than
434
00:20:05,049 --> 00:20:13,389
skin cancer is the most common cancer in
435
00:20:08,440 --> 00:20:16,840
the US and about one in seven men will
436
00:20:13,390 --> 00:20:18,580
be diagnosed with cancer and the
437
00:20:16,839 --> 00:20:20,559
estimated number of many ways prostate
438
00:20:18,579 --> 00:20:22,629
cancer is now close to three million
439
00:20:20,559 --> 00:20:27,099
people two million seven hundred
440
00:20:22,630 --> 00:20:29,830
thousand if caught early like many other
441
00:20:27,099 --> 00:20:32,709
cancers it is one of the most visible
442
00:20:29,829 --> 00:20:35,049
malignancies and it's a qualified
443
00:20:32,710 --> 00:20:36,900
statement though certain prostate
444
00:20:35,049 --> 00:20:39,460
cancers that are so aggressive that
445
00:20:36,900 --> 00:20:41,560
they're going to show up regardless of
446
00:20:39,460 --> 00:20:43,900
what you've got a reoccurring goddess of
447
00:20:41,559 --> 00:20:45,940
what we do but we don't have time to
448
00:20:43,900 --> 00:20:46,360
avoid this greater detail we can touch
449
00:20:45,940 --> 00:20:50,500
it
450
00:20:46,359 --> 00:20:51,939
what's really important is they you know
451
00:20:50,500 --> 00:20:53,769
underst why we understand it's the
452
00:20:51,940 --> 00:21:00,070
second leading cause of cancer deaths in
453
00:20:53,769 --> 00:21:02,049
American men behind lung cancer and we
454
00:21:00,069 --> 00:21:04,569
want to look at its average age so the
455
00:21:02,049 --> 00:21:06,990
average is it's 66 percent which still
456
00:21:04,569 --> 00:21:09,669
seem like it's an disease of all people
457
00:21:06,990 --> 00:21:13,000
it comes know you should say all people
458
00:21:09,670 --> 00:21:14,830
but not they young people but we have to
459
00:21:13,000 --> 00:21:16,150
understand we look at this data we
460
00:21:14,829 --> 00:21:22,059
really have to understand it's what's
461
00:21:16,150 --> 00:21:24,430
happening so our our survival that goes
462
00:21:22,059 --> 00:21:28,629
out many more people leads to the 80s
463
00:21:24,430 --> 00:21:31,570
into the 90s and just like BPH many men
464
00:21:28,630 --> 00:21:34,090
as they age and get older into the 80s
465
00:21:31,569 --> 00:21:36,000
90s can come up with what I often call
466
00:21:34,089 --> 00:21:39,129
physiological prostate cancer and
467
00:21:36,000 --> 00:21:40,390
low-grade Gleason 6 prostate cancer
468
00:21:39,130 --> 00:21:42,220
Gleason is the reflection of the
469
00:21:40,390 --> 00:21:45,280
aggressiveness of the prostate cancer
470
00:21:42,220 --> 00:21:47,559
with the lowest one being diagnosed as
471
00:21:45,279 --> 00:21:50,950
cancer is six in a very aggressive one
472
00:21:47,559 --> 00:21:53,529
is 10 it relates to genetic mutation and
473
00:21:50,950 --> 00:21:56,830
aggressiveness of the consumer so if we
474
00:21:53,529 --> 00:21:59,349
can look at 66 is a it's an average and
475
00:21:56,829 --> 00:22:03,039
we have two men who got prostate cancer
476
00:21:59,349 --> 00:22:06,429
at age 80 they will actually balance
477
00:22:03,039 --> 00:22:09,460
somebody's age 38 that got prostate
478
00:22:06,430 --> 00:22:10,660
cancer and we see now men in their
479
00:22:09,460 --> 00:22:13,569
thirties coming
480
00:22:10,660 --> 00:22:16,390
with prostate cancer very often more
481
00:22:13,569 --> 00:22:18,849
aggressive posture kids why the prostate
482
00:22:16,390 --> 00:22:22,180
cancer more aggressive one because the
483
00:22:18,849 --> 00:22:22,750
person metabolism physiology activity is
484
00:22:22,180 --> 00:22:25,210
faster
485
00:22:22,750 --> 00:22:27,460
everything is moving faster and second
486
00:22:25,210 --> 00:22:31,450
because more extreme factors were needed
487
00:22:27,460 --> 00:22:34,210
to produce prostate cancer over a
488
00:22:31,450 --> 00:22:35,799
shorter period of time we also have to
489
00:22:34,210 --> 00:22:39,160
remember we look at these statistics
490
00:22:35,799 --> 00:22:42,700
that now is PSA very commonly done
491
00:22:39,160 --> 00:22:44,800
compared to 34 years ago we are finding
492
00:22:42,700 --> 00:22:47,200
this benign non aggressive prostate
493
00:22:44,799 --> 00:22:49,240
cancer at later age we would have not
494
00:22:47,200 --> 00:22:51,279
found in the past people when just died
495
00:22:49,240 --> 00:22:54,339
was posted cancer that nobody knew about
496
00:22:51,279 --> 00:22:58,139
and this also skews the age to a higher
497
00:22:54,339 --> 00:23:00,669
age so the take-home takeaway point is
498
00:22:58,140 --> 00:23:03,840
don't disregard the possibility of
499
00:23:00,670 --> 00:23:05,950
having prostate cancer at a young age
500
00:23:03,839 --> 00:23:08,319
the other thing is a team dedicated
501
00:23:05,950 --> 00:23:12,509
slight when I want to end is the whole
502
00:23:08,319 --> 00:23:17,230
story of PSA so for me personally always
503
00:23:12,509 --> 00:23:19,839
PSA is great value PSA testing is great
504
00:23:17,230 --> 00:23:22,000
value when done appropriately going
505
00:23:19,839 --> 00:23:25,029
where it's done one in the contest of
506
00:23:22,000 --> 00:23:27,460
how big is the prostate because if the
507
00:23:25,029 --> 00:23:29,740
PSA is high with a very large prostate
508
00:23:27,460 --> 00:23:31,809
it's less worrisome because we can
509
00:23:29,740 --> 00:23:34,029
explain the PSA so if you have somebody
510
00:23:31,809 --> 00:23:36,250
were the digital rectal exam on
511
00:23:34,029 --> 00:23:40,690
ultrasound show the small and 30ml
512
00:23:36,250 --> 00:23:44,380
prostate 20 ml even 25 you will really
513
00:23:40,690 --> 00:23:48,730
expect these people to have under to PSA
514
00:23:44,380 --> 00:23:50,650
and the camera is 4.5 it's a concern but
515
00:23:48,730 --> 00:23:55,210
if somebody is a huge prostate which is
516
00:23:50,650 --> 00:23:56,920
80 ml and the PSA is 5.6 or 6 it can all
517
00:23:55,210 --> 00:23:59,559
expert be explained by the normal
518
00:23:56,920 --> 00:24:02,400
excretion from the tissue the other part
519
00:23:59,559 --> 00:24:05,950
is a type II assay with urinary symptoms
520
00:24:02,400 --> 00:24:09,040
is less worrisome than high PSA without
521
00:24:05,950 --> 00:24:11,110
M C because again we can explain it so
522
00:24:09,039 --> 00:24:12,849
in my perspective I use PSA to
523
00:24:11,109 --> 00:24:15,639
understand the patient and then I look
524
00:24:12,849 --> 00:24:18,759
at many other metabolites and many other
525
00:24:15,640 --> 00:24:23,490
factors both in the one-on-one care and
526
00:24:18,759 --> 00:24:23,490
both of us formulate products
527
00:24:24,970 --> 00:24:30,919
so what is the integrative approach to
528
00:24:28,460 --> 00:24:34,370
to to prostate cancer which I touched
529
00:24:30,919 --> 00:24:36,500
about a little bit before so we can see
530
00:24:34,369 --> 00:24:39,649
the approach to prostate cancer is
531
00:24:36,500 --> 00:24:42,798
multi-pronged I want to emphasize it
532
00:24:39,650 --> 00:24:44,419
from a from a conventional medicine
533
00:24:42,798 --> 00:24:46,339
point of view there's a lot of exciting
534
00:24:44,419 --> 00:24:47,690
new treatment I just did a chance to
535
00:24:46,339 --> 00:24:50,928
present an Oscar
536
00:24:47,690 --> 00:24:52,669
gee you asked genitourinary annual
537
00:24:50,929 --> 00:24:56,120
conference in San Francisco in February
538
00:24:52,669 --> 00:24:58,070
our study modified it was picked in
539
00:24:56,119 --> 00:25:01,278
which I will share in a moment and there
540
00:24:58,069 --> 00:25:04,759
were some very big news about some new
541
00:25:01,278 --> 00:25:06,380
drug extended for long term prostate
542
00:25:04,759 --> 00:25:11,720
cancer patient or failing hormonal
543
00:25:06,380 --> 00:25:14,778
therapy and this is good news but the
544
00:25:11,720 --> 00:25:17,990
drug that you are going to get is not
545
00:25:14,778 --> 00:25:20,390
driven by who you are but what but by
546
00:25:17,990 --> 00:25:23,778
which mechanisms of action are driving
547
00:25:20,390 --> 00:25:27,070
your treatment it's sometime remarkable
548
00:25:23,778 --> 00:25:30,288
for example if we look at the field of
549
00:25:27,069 --> 00:25:33,769
immunotherapy like PDL 1 inhibitor of
550
00:25:30,288 --> 00:25:37,669
CTL foreign immatures you check for the
551
00:25:33,769 --> 00:25:39,079
receptors for these molecules and I
552
00:25:37,669 --> 00:25:42,980
won't go into the detail of what they
553
00:25:39,079 --> 00:25:45,288
are but even if make a large Institute's
554
00:25:42,980 --> 00:25:48,500
you know the largest Cancer Institute
555
00:25:45,288 --> 00:25:50,750
they will not try to understand the
556
00:25:48,500 --> 00:25:52,940
immune system in a deeper more
557
00:25:50,750 --> 00:25:55,819
comprehensive way because it's not
558
00:25:52,940 --> 00:25:59,240
needed it's not indicated to give the
559
00:25:55,819 --> 00:26:01,879
drug so this is as we made progress
560
00:25:59,240 --> 00:26:03,740
these drugs are important but we really
561
00:26:01,880 --> 00:26:06,049
want to understand what is driving the
562
00:26:03,740 --> 00:26:08,890
condition because for each of us there
563
00:26:06,048 --> 00:26:11,119
are different things so as I often say
564
00:26:08,890 --> 00:26:13,100
conventional treatments for cancer can
565
00:26:11,119 --> 00:26:15,379
get very good results so let's say we
566
00:26:13,099 --> 00:26:18,469
look at at the breast cancer we do not
567
00:26:15,380 --> 00:26:20,330
the topic or often a chemotherapy is a
568
00:26:18,470 --> 00:26:23,028
very late stage in prostate cancer but a
569
00:26:20,329 --> 00:26:24,769
certain treatment that is a 70% response
570
00:26:23,028 --> 00:26:26,839
it doesn't matter
571
00:26:24,769 --> 00:26:30,019
which doctor you go to you're gonna get
572
00:26:26,839 --> 00:26:32,839
the same treatment with 70% it will take
573
00:26:30,019 --> 00:26:35,839
an integrative doctor a lot of work
574
00:26:32,839 --> 00:26:40,428
creativity and unique know how to take
575
00:26:35,839 --> 00:26:44,359
up from let's say 70 to 72 or 75 of 80
576
00:26:40,429 --> 00:26:48,019
or 82 in order to take it up to 80 when
577
00:26:44,359 --> 00:26:51,918
you reduced the risk you improve the
578
00:26:48,019 --> 00:26:54,528
response the survival of the 30% by 1/3
579
00:26:51,919 --> 00:26:56,960
but what's so important that when we do
580
00:26:54,528 --> 00:26:59,750
it we have a very important side effect
581
00:26:56,960 --> 00:27:01,700
we feel better emotionally we feel
582
00:26:59,750 --> 00:27:03,919
better physically we are more productive
583
00:27:01,700 --> 00:27:06,140
we are happier there's part of an
584
00:27:03,919 --> 00:27:08,570
integrative approach I want to emphasize
585
00:27:06,140 --> 00:27:11,059
this because you can always integrate it
586
00:27:08,569 --> 00:27:12,558
into your care so looking at these
587
00:27:11,058 --> 00:27:16,428
factors now you want to look at some
588
00:27:12,558 --> 00:27:19,700
important issues so immune enhancement
589
00:27:16,429 --> 00:27:24,350
is very important it's not as important
590
00:27:19,700 --> 00:27:26,929
in hormonal driven tumors but we do
591
00:27:24,349 --> 00:27:28,490
whenever good in your response and we
592
00:27:26,929 --> 00:27:32,750
want to make sure that the immune
593
00:27:28,490 --> 00:27:35,058
response can get to the cancer cell what
594
00:27:32,750 --> 00:27:38,000
do I mean we're gonna have a strong
595
00:27:35,058 --> 00:27:41,778
immune response and let's say we
596
00:27:38,000 --> 00:27:43,369
increase certainly a compound that can
597
00:27:41,778 --> 00:27:47,750
kill cancer like tumor necrosis
598
00:27:43,369 --> 00:27:50,209
factor-alpha TNF alpha if the tumor is
599
00:27:47,750 --> 00:27:53,648
shielding itself from the system its
600
00:27:50,210 --> 00:27:57,649
coating itself with the system the the
601
00:27:53,648 --> 00:28:00,048
compound will not be able to get to the
602
00:27:57,648 --> 00:28:02,319
cancer and if the cancer in children and
603
00:28:00,048 --> 00:28:05,210
creates a micro environment with its own
604
00:28:02,319 --> 00:28:07,990
metabolic environment its own PA
605
00:28:05,210 --> 00:28:11,269
its own growth factor it becomes an
606
00:28:07,990 --> 00:28:13,190
independent entity within our body and
607
00:28:11,269 --> 00:28:15,769
our immune system doesn't live the way
608
00:28:13,190 --> 00:28:18,288
to address it so immune enhancement is
609
00:28:15,769 --> 00:28:19,849
not such a simple concept and we now see
610
00:28:18,288 --> 00:28:22,730
it we see it for example with
611
00:28:19,849 --> 00:28:26,058
immunotherapies that can give benefits
612
00:28:22,730 --> 00:28:28,099
but the benefits are related also to
613
00:28:26,058 --> 00:28:31,278
side-effects to inflammatory side
614
00:28:28,099 --> 00:28:33,408
effects because because there is no
615
00:28:31,278 --> 00:28:35,119
change in the local tissues if you fight
616
00:28:33,409 --> 00:28:37,669
it and there's already inflammation will
617
00:28:35,119 --> 00:28:40,609
become worse the other part which is
618
00:28:37,669 --> 00:28:43,490
very important in prostate it's hormonal
619
00:28:40,609 --> 00:28:47,509
and metabolic modulation and modulation
620
00:28:43,490 --> 00:28:49,430
is beyond just hormonal therapy we have
621
00:28:47,509 --> 00:28:51,799
to understand the patient
622
00:28:49,430 --> 00:28:53,600
or Monali before you take your first
623
00:28:51,799 --> 00:28:56,000
treatment I always say this is the map
624
00:28:53,599 --> 00:28:58,279
this is a baseline and if we don't take
625
00:28:56,000 --> 00:29:01,609
a good picture we can never come back
626
00:28:58,279 --> 00:29:04,670
so for numbering the clinic I will run a
627
00:29:01,609 --> 00:29:07,899
lot of lunches no of course this Joss
628
00:29:04,670 --> 00:29:11,570
Stone and the in DHT and total esposende
629
00:29:07,900 --> 00:29:16,340
in the different estrogen and igf-1 and
630
00:29:11,569 --> 00:29:17,659
prolactin and the hemoglobin a1c and I
631
00:29:16,339 --> 00:29:20,059
want to see the relationship between
632
00:29:17,660 --> 00:29:22,340
them I will look at different a
633
00:29:20,059 --> 00:29:24,579
different compound that can affect them
634
00:29:22,339 --> 00:29:27,859
and then I will look at metabolic
635
00:29:24,579 --> 00:29:33,169
factors thyroid function adrenal
636
00:29:27,859 --> 00:29:35,449
function cortisol and see how they
637
00:29:33,170 --> 00:29:37,880
relate to each other in the specific
638
00:29:35,450 --> 00:29:40,130
person why is this so important if
639
00:29:37,880 --> 00:29:44,240
you're gonna give the same drug because
640
00:29:40,130 --> 00:29:46,760
if you take a good sniff shot of what
641
00:29:44,240 --> 00:29:50,059
happened before you start treating you
642
00:29:46,759 --> 00:29:53,210
are being shown the road that cut you
643
00:29:50,059 --> 00:29:55,700
into this situation and then when you
644
00:29:53,210 --> 00:29:58,039
want to backtrack make the treatment
645
00:29:55,700 --> 00:30:00,860
more effective or continue holistic
646
00:29:58,039 --> 00:30:03,740
approaches after formal therapy that's
647
00:30:00,859 --> 00:30:06,829
so important to really understand very I
648
00:30:03,740 --> 00:30:08,390
can't emphasize this enough and they're
649
00:30:06,829 --> 00:30:12,740
not done often enough
650
00:30:08,390 --> 00:30:16,670
I regret because we live because of cost
651
00:30:12,740 --> 00:30:18,170
insurance driven medicine so then when
652
00:30:16,670 --> 00:30:20,660
we look at this when you look at direct
653
00:30:18,170 --> 00:30:24,320
cytotoxicity how can we directly attack
654
00:30:20,660 --> 00:30:28,310
the cancer if it's botanicals if it's
655
00:30:24,319 --> 00:30:31,009
other compounds etcetera so driving
656
00:30:28,309 --> 00:30:33,169
cytotoxicity INRI differentiation are
657
00:30:31,009 --> 00:30:35,629
closely related one of them tries to
658
00:30:33,170 --> 00:30:38,269
kill and one of them tries to make the
659
00:30:35,630 --> 00:30:41,870
sale normal so for example certain
660
00:30:38,269 --> 00:30:44,180
things like vitamin D vitamin a sodium
661
00:30:41,869 --> 00:30:46,839
vanilla Beauty rate or no key on which
662
00:30:44,180 --> 00:30:49,279
is key helped in we differentiation
663
00:30:46,839 --> 00:30:51,409
modified citrus pectin also does it
664
00:30:49,279 --> 00:30:54,379
because the mother is an expression of
665
00:30:51,410 --> 00:30:56,660
collecting 3 the more that cancer is in
666
00:30:54,380 --> 00:30:58,100
the female of cells in the cancer stem
667
00:30:56,660 --> 00:31:01,190
cells become more aggressive
668
00:30:58,099 --> 00:31:03,079
exactly key mechanism we want to balance
669
00:31:01,190 --> 00:31:05,659
addressing both of them
670
00:31:03,079 --> 00:31:07,278
either in the same time or if you're
671
00:31:05,659 --> 00:31:10,850
getting a certain treatment within the
672
00:31:07,278 --> 00:31:13,159
treatment cycle for example my a my
673
00:31:10,849 --> 00:31:15,949
clinic I adjust the supplements based
674
00:31:13,159 --> 00:31:18,649
someone is doing in a dynamic way where
675
00:31:15,950 --> 00:31:19,940
it changes over let's say somebody gets
676
00:31:18,648 --> 00:31:22,849
a certain treatment every three weeks
677
00:31:19,940 --> 00:31:25,460
the supplements will change again I try
678
00:31:22,849 --> 00:31:27,469
to reflect this as much as I came in in
679
00:31:25,460 --> 00:31:30,860
a sleeper supplement that's why you need
680
00:31:27,470 --> 00:31:33,829
so many Gideon's we also want to
681
00:31:30,859 --> 00:31:36,229
recognize detoxification heavy-metal
682
00:31:33,829 --> 00:31:39,168
environmental toxins have direct effect
683
00:31:36,230 --> 00:31:42,620
on the prostate why because heavy metals
684
00:31:39,169 --> 00:31:45,380
are heavy the process is the lowest part
685
00:31:42,619 --> 00:31:48,199
in our torso so naturally heavy metal
686
00:31:45,380 --> 00:31:53,690
will sink into this area if we look at
687
00:31:48,200 --> 00:31:56,750
cancer in men in children we can get of
688
00:31:53,690 --> 00:31:59,630
course different bone marrow cancers you
689
00:31:56,750 --> 00:32:01,960
know in central nervous system cancer
690
00:31:59,630 --> 00:32:06,528
that relate a little bit to the same
691
00:32:01,960 --> 00:32:09,340
system Chinese medicine and then we can
692
00:32:06,528 --> 00:32:12,798
get osteosarcoma cancer of the bones
693
00:32:09,339 --> 00:32:14,569
below the pelvis beautifully and then
694
00:32:12,798 --> 00:32:18,500
the first cancer we get is we get to
695
00:32:14,569 --> 00:32:20,808
stick with our cancer and afterwards
696
00:32:18,500 --> 00:32:25,069
we'll start moving upward and we get
697
00:32:20,808 --> 00:32:27,379
frost occurs similary minutes in their
698
00:32:25,069 --> 00:32:29,720
cancers so we can see a little sis it is
699
00:32:27,380 --> 00:32:31,700
sinking into the bathroom and that's
700
00:32:29,720 --> 00:32:34,130
where dietary changes detoxification
701
00:32:31,700 --> 00:32:37,399
herb removal of heavy metals can be very
702
00:32:34,130 --> 00:32:40,429
important in the same category with
703
00:32:37,398 --> 00:32:42,859
conditions with with related importance
704
00:32:40,429 --> 00:32:46,070
is addressing circulation in hyper
705
00:32:42,859 --> 00:32:48,259
viscosity if the blood is too thick if
706
00:32:46,069 --> 00:32:51,558
the circulation is not normal we'll get
707
00:32:48,259 --> 00:32:53,599
tissue which is his hype oxidation
708
00:32:51,558 --> 00:32:56,509
doesn't have enough oxygen it becomes
709
00:32:53,599 --> 00:33:00,678
more synthetic more lactic acid lactic
710
00:32:56,509 --> 00:33:03,109
acid increases hypoxia and using factors
711
00:33:00,679 --> 00:33:05,028
which again shuts down the mitochondria
712
00:33:03,109 --> 00:33:06,619
because about economy our consumption
713
00:33:05,028 --> 00:33:10,220
there's no oxygen that can produce
714
00:33:06,619 --> 00:33:12,439
energy and now it's a vicious cycle and
715
00:33:10,220 --> 00:33:15,970
for example a drug like metformin is
716
00:33:12,440 --> 00:33:18,269
very important in addressing it and
717
00:33:15,970 --> 00:33:21,870
more effective is on opioid doctor we
718
00:33:18,269 --> 00:33:24,819
specifically addressed the metabolic
719
00:33:21,869 --> 00:33:26,319
component that will affect we
720
00:33:24,819 --> 00:33:30,609
differentiation from the point of view
721
00:33:26,319 --> 00:33:32,919
of re-establishing normal mitochondrial
722
00:33:30,609 --> 00:33:35,740
function turning an abnormal cell into a
723
00:33:32,920 --> 00:33:39,519
normal cell but also because there is
724
00:33:35,740 --> 00:33:42,220
not a see more cyclic a and P being
725
00:33:39,519 --> 00:33:44,470
produced there is more normal function
726
00:33:42,220 --> 00:33:46,900
of the cell a little example of one
727
00:33:44,470 --> 00:33:49,600
compound like Pinocchio that can work in
728
00:33:46,900 --> 00:33:53,980
so many places and is this very unique
729
00:33:49,599 --> 00:33:56,230
quality to to recognize cancer cell in
730
00:33:53,980 --> 00:33:58,539
three different and then prevention of
731
00:33:56,230 --> 00:34:00,400
metastasis and your Genesis where
732
00:33:58,539 --> 00:34:04,269
modified is respecting is the leading
733
00:34:00,400 --> 00:34:08,619
compound with soly data in vitro in vivo
734
00:34:04,269 --> 00:34:10,329
and multiple human clinical trials so
735
00:34:08,619 --> 00:34:12,789
let's talk a little bit about galatians
736
00:34:10,329 --> 00:34:14,650
being motivated respecting that's a
737
00:34:12,789 --> 00:34:19,599
field that we've been involved with for
738
00:34:14,650 --> 00:34:22,150
almost almost 25 years for 23 years now
739
00:34:19,599 --> 00:34:24,250
and i'll share with you just some
740
00:34:22,150 --> 00:34:29,680
highlights because there's too much to
741
00:34:24,250 --> 00:34:33,309
share a few minutes a modified c2
742
00:34:29,679 --> 00:34:36,969
expecting binds and blocks the adverse
743
00:34:33,309 --> 00:34:41,559
effect of collectively collecting three
744
00:34:36,969 --> 00:34:44,980
is a protein that binds carbohydrate so
745
00:34:41,559 --> 00:34:48,130
it binds oxidized glycolipids like a
746
00:34:44,980 --> 00:34:51,429
proteins and when it binded to create a
747
00:34:48,130 --> 00:34:54,010
lattice formation covering the cover
748
00:34:51,429 --> 00:34:57,069
that covers the tumor cells and allow
749
00:34:54,010 --> 00:35:00,460
the tumors to height they cover that
750
00:34:57,070 --> 00:35:02,769
allows that shuts down the response of
751
00:35:00,460 --> 00:35:04,389
the immune cells and there's a lot of
752
00:35:02,769 --> 00:35:07,269
other effects of inflammation in
753
00:35:04,389 --> 00:35:09,369
fibrosis but specifically in cancer
754
00:35:07,269 --> 00:35:11,530
exposure log electives we will promote
755
00:35:09,369 --> 00:35:13,869
as you can see in the slide aggregation
756
00:35:11,530 --> 00:35:16,480
of cancer cells tumor growth invasion
757
00:35:13,869 --> 00:35:18,460
and migration of the tumor immunization
758
00:35:16,480 --> 00:35:21,940
explained greatly how by surrounding
759
00:35:18,460 --> 00:35:24,929
they say as a tumor cell angiogenesis
760
00:35:21,940 --> 00:35:27,130
growth of new blood vessel because PGs
761
00:35:24,929 --> 00:35:29,779
father endothelial growth factor
762
00:35:27,130 --> 00:35:32,300
attaches to the galatians we
763
00:35:29,780 --> 00:35:35,240
vision of apoptosis cell cannot just
764
00:35:32,300 --> 00:35:38,150
diet keeps living emitters metastasis
765
00:35:35,239 --> 00:35:40,209
the initial work in modifies it
766
00:35:38,150 --> 00:35:42,470
respecting most specifically metastasis
767
00:35:40,210 --> 00:35:46,070
newspapers published in the leading
768
00:35:42,469 --> 00:35:48,159
journals so ladies we really is a master
769
00:35:46,070 --> 00:35:50,960
conductor of the tumor microenvironment
770
00:35:48,159 --> 00:35:53,659
it's similar to refer to proliferation
771
00:35:50,960 --> 00:35:56,420
in inhibit apoptosis intracellular
772
00:35:53,659 --> 00:35:59,420
effects it stimulate migration promotes
773
00:35:56,420 --> 00:36:01,909
invasion metastasis formation cell to
774
00:35:59,420 --> 00:36:05,180
cell interaction and stimulates at
775
00:36:01,909 --> 00:36:08,509
Genesis inhibits immune surveillance and
776
00:36:05,179 --> 00:36:11,419
bio mentally regulation so you can see
777
00:36:08,510 --> 00:36:14,240
how the levels are coming from benefits
778
00:36:11,420 --> 00:36:16,579
inside the cell our cell to cell
779
00:36:14,239 --> 00:36:19,489
interaction and how they're in effects
780
00:36:16,579 --> 00:36:23,239
that effects the whole system very
781
00:36:19,489 --> 00:36:25,479
unique so while collecting three inside
782
00:36:23,239 --> 00:36:28,699
the nucleus of the cell has important
783
00:36:25,480 --> 00:36:31,639
issues when it comes into the cytoplasm
784
00:36:28,699 --> 00:36:35,359
of the cell when it comes outside it
785
00:36:31,639 --> 00:36:37,309
really serves to repair injury and it
786
00:36:35,360 --> 00:36:39,769
repairs injury by causing inflammation
787
00:36:37,309 --> 00:36:42,409
and fibrosis the attended the trial
788
00:36:39,769 --> 00:36:44,059
mental effect on every chronic condition
789
00:36:42,409 --> 00:36:46,159
and the initial interest was
790
00:36:44,059 --> 00:36:47,960
specifically on cancer and we've been
791
00:36:46,159 --> 00:36:50,589
studying now the effect of corrected to
792
00:36:47,960 --> 00:36:58,400
be blocker mod affected expected in
793
00:36:50,590 --> 00:37:00,860
prostate cancer for 23 years so this is
794
00:36:58,400 --> 00:37:02,539
really how we talked about these tweaks
795
00:37:00,860 --> 00:37:04,220
we categorize and you can see how
796
00:37:02,539 --> 00:37:07,579
together they will just make cancer
797
00:37:04,219 --> 00:37:09,339
survive and become more aggressive so
798
00:37:07,579 --> 00:37:11,329
what is more effective especially
799
00:37:09,340 --> 00:37:14,809
picketing is a low
800
00:37:11,329 --> 00:37:17,420
complex chain of a polysaccharide fiber
801
00:37:14,809 --> 00:37:18,230
electronic acid you can see it below the
802
00:37:17,420 --> 00:37:20,659
blue chart
803
00:37:18,230 --> 00:37:23,420
most of it is terrified the one in green
804
00:37:20,659 --> 00:37:27,109
and a few of them are not as terrifying
805
00:37:23,420 --> 00:37:29,240
and it is neutral sugars like randos
806
00:37:27,110 --> 00:37:31,750
arabinose which are very many components
807
00:37:29,239 --> 00:37:35,299
like new recognition or detoxification
808
00:37:31,750 --> 00:37:37,099
also is ramlak electron and - I mean our
809
00:37:35,300 --> 00:37:38,620
specific modified citrus pectin we
810
00:37:37,099 --> 00:37:41,779
published with the USDA
811
00:37:38,619 --> 00:37:43,670
10% from the electron and - which is a
812
00:37:41,780 --> 00:37:47,359
compound present in mistletoe which
813
00:37:43,670 --> 00:37:50,389
meaning Union answer so in order for it
814
00:37:47,358 --> 00:37:52,548
to be beneficial we have to cut it to a
815
00:37:50,389 --> 00:37:55,759
very low molecular weight so it didn't
816
00:37:52,548 --> 00:37:57,679
get easily absorbed by the GI tract and
817
00:37:55,760 --> 00:38:00,290
we have to create a certain structure
818
00:37:57,679 --> 00:38:02,659
that will be biologically active and
819
00:38:00,289 --> 00:38:05,960
will exert its benefits and we have
820
00:38:02,659 --> 00:38:08,808
shown now by developing an antibody to
821
00:38:05,960 --> 00:38:12,619
our modifies it was effective that it
822
00:38:08,809 --> 00:38:16,670
can actually be absorbed into the blood
823
00:38:12,619 --> 00:38:19,059
work and create its benefit and let me
824
00:38:16,670 --> 00:38:23,000
say a word about modified it was good
825
00:38:19,059 --> 00:38:25,220
it's really a generic chain name because
826
00:38:23,000 --> 00:38:26,960
every patient is to be modified to be
827
00:38:25,219 --> 00:38:31,519
produced it is to be pulled out of the
828
00:38:26,960 --> 00:38:33,679
peel and is our research continues as we
829
00:38:31,519 --> 00:38:37,130
now just finishing two double-a clinical
830
00:38:33,679 --> 00:38:39,739
trials on osteoarthritis in hypertension
831
00:38:37,130 --> 00:38:42,858
with Harvard is we published more than
832
00:38:39,739 --> 00:38:45,318
40 papers on our specific motivated
833
00:38:42,858 --> 00:38:47,779
respect in Invictus or see there's a lot
834
00:38:45,318 --> 00:38:49,009
of powered science so you really want to
835
00:38:47,780 --> 00:38:51,079
make sure that you are using the
836
00:38:49,010 --> 00:38:53,540
specific preparation that was research
837
00:38:51,079 --> 00:38:56,900
entities whether the discoveries were
838
00:38:53,539 --> 00:39:00,079
were made of because it's a really
839
00:38:56,900 --> 00:39:03,230
important dietary supplement fiber which
840
00:39:00,079 --> 00:39:04,970
is a must for every person so I'm just
841
00:39:03,230 --> 00:39:06,260
touching very briefly of the research
842
00:39:04,969 --> 00:39:08,568
and what offensive respect and in
843
00:39:06,260 --> 00:39:11,869
prostate cancer especially on their two
844
00:39:08,568 --> 00:39:14,029
most important you're maintaining that
845
00:39:11,869 --> 00:39:16,818
our phase two pilot study was done on
846
00:39:14,030 --> 00:39:21,079
ten men with biochemical posted cancer
847
00:39:16,818 --> 00:39:24,230
relapse using 15 percent 15 gram and
848
00:39:21,079 --> 00:39:27,230
days for one year these patients were
849
00:39:24,230 --> 00:39:30,079
off any drugs for six months and we had
850
00:39:27,230 --> 00:39:30,530
a very significant improvement in the
851
00:39:30,079 --> 00:39:32,900
study
852
00:39:30,530 --> 00:39:34,790
these are study with biochemical relapse
853
00:39:32,900 --> 00:39:39,048
which means the prostate was removed
854
00:39:34,789 --> 00:39:40,849
there is no prostate and PSA zero or
855
00:39:39,048 --> 00:39:45,679
next to zero and then it starts coming
856
00:39:40,849 --> 00:39:50,750
back as a cancer occurs and it reoccurs
857
00:39:45,679 --> 00:39:52,940
the speed of elevation of L fare of PSA
858
00:39:50,750 --> 00:39:55,309
is proportional to the growth of cancer
859
00:39:52,940 --> 00:39:57,200
well-established and we're able to slow
860
00:39:55,309 --> 00:39:59,450
it down to increase
861
00:39:57,199 --> 00:40:01,578
the time it takes for the PSA to double
862
00:39:59,449 --> 00:40:05,539
in seven out of ten men
863
00:40:01,579 --> 00:40:10,970
his p-value under 0.01 with the AIDS one
864
00:40:05,539 --> 00:40:13,309
in there if it was under 0.05 so you can
865
00:40:10,969 --> 00:40:14,809
see that even there even a pro patient
866
00:40:13,309 --> 00:40:17,570
number four still and it's slowing down
867
00:40:14,809 --> 00:40:19,759
of the process but it wasn't under 0.01
868
00:40:17,570 --> 00:40:21,800
and these are all patient with seeking
869
00:40:19,760 --> 00:40:24,740
clinically significant prostate cancer
870
00:40:21,800 --> 00:40:25,579
which is growing fast why is this so
871
00:40:24,739 --> 00:40:28,279
important
872
00:40:25,579 --> 00:40:31,359
that's another compounded came down PSA
873
00:40:28,280 --> 00:40:34,220
because if we do it in a non hormonal
874
00:40:31,358 --> 00:40:36,469
mechanism we do it without manipulating
875
00:40:34,219 --> 00:40:40,848
the hormonal picture because once we
876
00:40:36,469 --> 00:40:42,649
change so model expression of constant
877
00:40:40,849 --> 00:40:45,470
cancer we start messing up with the
878
00:40:42,650 --> 00:40:48,139
biology of the cancer modified it to
879
00:40:45,469 --> 00:40:53,419
speak is so unique that it binds to
880
00:40:48,139 --> 00:40:55,848
collected 3 it it shuts down all of this
881
00:40:53,420 --> 00:40:58,460
aggressive mechanisms it enhances the
882
00:40:55,849 --> 00:41:02,240
immune system it removes heavy metals
883
00:40:58,460 --> 00:41:06,318
and it can do it on a long-term basis
884
00:41:02,239 --> 00:41:10,989
because not hormonal e involved we
885
00:41:06,318 --> 00:41:16,539
developed hormonal adjustments so
886
00:41:10,989 --> 00:41:16,539
interesting the same data was presented
887
00:41:17,019 --> 00:41:20,869
actually no this is a different slide I
888
00:41:19,159 --> 00:41:22,848
was going to show you another flap adult
889
00:41:20,869 --> 00:41:26,838
secretion in this time there's an
890
00:41:22,849 --> 00:41:29,599
example of one of the patients so if we
891
00:41:26,838 --> 00:41:31,578
were just affecting the metastasis you
892
00:41:29,599 --> 00:41:33,980
get a straight line because the primary
893
00:41:31,579 --> 00:41:36,380
tumor will still grow but you can see
894
00:41:33,980 --> 00:41:38,389
where the error is at the moment we
895
00:41:36,380 --> 00:41:39,980
start eating modified it respected we
896
00:41:38,389 --> 00:41:42,679
checked it for six months before it was
897
00:41:39,980 --> 00:41:46,309
a straight line linear increase it
898
00:41:42,679 --> 00:41:48,199
immediately affects the PSA rise which
899
00:41:46,309 --> 00:41:50,869
means it's affecting the growth of the
900
00:41:48,199 --> 00:41:52,669
primary tumor and the metastatic process
901
00:41:50,869 --> 00:41:55,220
and that's because of its anti
902
00:41:52,670 --> 00:41:57,619
angiogenesis and will develop these
903
00:41:55,219 --> 00:42:00,289
patients 20 months look how it's
904
00:41:57,619 --> 00:42:01,608
flattening at the end so you understand
905
00:42:00,289 --> 00:42:04,099
every day
906
00:42:01,608 --> 00:42:07,519
the modified retrospective slows down
907
00:42:04,099 --> 00:42:10,220
the growth of cancer is an eighth day of
908
00:42:07,519 --> 00:42:11,389
life because we are not messing with the
909
00:42:10,219 --> 00:42:14,028
hormonal mechanic
910
00:42:11,389 --> 00:42:21,409
which creates mutated tumors and more
911
00:42:14,028 --> 00:42:23,298
questions so we are now we've been
912
00:42:21,409 --> 00:42:25,058
engaged now for four years in what was
913
00:42:23,298 --> 00:42:27,288
supposed to be a shade three
914
00:42:25,059 --> 00:42:28,940
double-blind clinical trial but because
915
00:42:27,289 --> 00:42:32,299
it's low in treatment was changed to
916
00:42:28,940 --> 00:42:34,548
face to be multicenter perspective they
917
00:42:32,298 --> 00:42:36,739
study that he's testing the
918
00:42:34,548 --> 00:42:39,199
effectiveness of motivated inspecting in
919
00:42:36,739 --> 00:42:40,788
the treatment of PSA dynamics in all
920
00:42:39,199 --> 00:42:42,889
metastatic biochemically we'll have to
921
00:42:40,789 --> 00:42:47,619
post it again I'm just reading you the
922
00:42:42,889 --> 00:42:52,058
title from the ASCO 2018 poster
923
00:42:47,619 --> 00:42:58,690
presentation and this was a pre-planned
924
00:42:52,059 --> 00:42:58,690
analysis of fare 50% of the patients and
925
00:42:59,289 --> 00:43:07,130
so after we have 50% of more than 50% of
926
00:43:02,989 --> 00:43:10,308
the patient finished six months we are
927
00:43:07,130 --> 00:43:13,039
presenting it and we expect in these
928
00:43:10,309 --> 00:43:16,190
patients that 80% of the patients will
929
00:43:13,039 --> 00:43:18,650
progress in six months and right now we
930
00:43:16,190 --> 00:43:21,159
already had 45 patient enrolled and we
931
00:43:18,650 --> 00:43:25,400
hope to publish data on 50 patients so
932
00:43:21,159 --> 00:43:27,739
longer term data so what did we do in
933
00:43:25,400 --> 00:43:29,930
this study we took patient with
934
00:43:27,739 --> 00:43:32,000
biochemically when limits relapse
935
00:43:29,929 --> 00:43:33,980
prostate cancer after primary tumor
936
00:43:32,000 --> 00:43:38,298
treatment either surgery radiation of
937
00:43:33,980 --> 00:43:41,150
both we confirmed rising PSA monthly
938
00:43:38,298 --> 00:43:43,369
time 3 so we had a straight line and we
939
00:43:41,150 --> 00:43:45,108
could calculate the doubling time we
940
00:43:43,369 --> 00:43:47,930
confirmed that testosterone is at normal
941
00:43:45,108 --> 00:43:51,170
levels there is no unwritten deprivation
942
00:43:47,929 --> 00:43:52,759
treatments for at least 3 months and the
943
00:43:51,170 --> 00:43:56,000
PET scan of Vaughn scan
944
00:43:52,759 --> 00:43:59,028
law CT scans are negative patient were
945
00:43:56,000 --> 00:44:02,000
evaluated monthly and they were
946
00:43:59,028 --> 00:44:04,989
receiving 6 months of oral mCP therapy
947
00:44:02,000 --> 00:44:08,028
for my Datagram 3 times a day and
948
00:44:04,989 --> 00:44:10,459
disease status piercing scams at 6
949
00:44:08,028 --> 00:44:12,949
months and then we divided it - no
950
00:44:10,460 --> 00:44:15,139
progression which means it stopped going
951
00:44:12,949 --> 00:44:19,268
up remember hundred percent of these
952
00:44:15,139 --> 00:44:22,038
patients are progressive right now and
953
00:44:19,268 --> 00:44:25,159
if they progress they were taken of the
954
00:44:22,039 --> 00:44:25,880
study and when we in progression we
955
00:44:25,159 --> 00:44:29,750
define
956
00:44:25,880 --> 00:44:33,260
25% increase in PSA from baseline our
957
00:44:29,750 --> 00:44:35,239
skin progression on limiting toxicity
958
00:44:33,260 --> 00:44:36,770
and I want to mention it's a little bit
959
00:44:35,239 --> 00:44:39,049
of an issue because if you can have
960
00:44:36,769 --> 00:44:41,900
somebody and if somebody who's PC is
961
00:44:39,050 --> 00:44:45,289
going up very quickly you improve them
962
00:44:41,900 --> 00:44:47,780
but they still went up by 25% during the
963
00:44:45,289 --> 00:44:50,690
six four months let's say because before
964
00:44:47,780 --> 00:44:52,820
they will go up by 50% and still they
965
00:44:50,690 --> 00:44:56,179
will not qualify even if you're actually
966
00:44:52,820 --> 00:45:00,080
helping so the results were fascinating
967
00:44:56,179 --> 00:45:02,449
first of all in general 79% of the 34
968
00:45:00,079 --> 00:45:05,679
patient benefited from modified citrus
969
00:45:02,449 --> 00:45:10,969
pectin which is remarkable out of these
970
00:45:05,679 --> 00:45:12,949
out of these patients a 62 percent of
971
00:45:10,969 --> 00:45:15,889
the hundred percent out of the 79
972
00:45:12,949 --> 00:45:19,009
percent most of them create 60 percent
973
00:45:15,889 --> 00:45:21,319
out of a hundred that was the PI of 79%
974
00:45:19,010 --> 00:45:23,900
and I can't show you in the pointer
975
00:45:21,320 --> 00:45:28,610
because it's on your screen 62 percent
976
00:45:23,900 --> 00:45:31,010
the PSA became slept or went down 17
977
00:45:28,610 --> 00:45:34,970
percent it continued to go up but slower
978
00:45:31,010 --> 00:45:37,880
than before only 21% of the patient did
979
00:45:34,969 --> 00:45:40,669
no PSA doubling time improvement most of
980
00:45:37,880 --> 00:45:45,340
them just the PSA going up and only nine
981
00:45:40,670 --> 00:45:45,340
percent had a change in finding the skin
982
00:45:46,000 --> 00:45:54,469
so this very strongly confirmed our
983
00:45:52,099 --> 00:45:56,239
observation of the benefit of modified
984
00:45:54,469 --> 00:45:58,129
citrus pectin so again to summarize
985
00:45:56,239 --> 00:45:59,899
they're all patient and persecuting
986
00:45:58,130 --> 00:46:03,579
rightly VPSA
987
00:45:59,900 --> 00:46:06,320
62 percent had no progression 2134
988
00:46:03,579 --> 00:46:08,779
stable or decreasing PSA levels and
989
00:46:06,320 --> 00:46:10,820
there were no safety issues the most
990
00:46:08,780 --> 00:46:14,180
common side effect was bloating which is
991
00:46:10,820 --> 00:46:16,940
dose dependent it usually goes away so
992
00:46:14,179 --> 00:46:19,669
very exciting very exciting confirmation
993
00:46:16,940 --> 00:46:22,849
of the benefits of but what was
994
00:46:19,670 --> 00:46:24,590
interesting for us is they to here what
995
00:46:22,849 --> 00:46:26,059
is the impression of some patients who
996
00:46:24,590 --> 00:46:28,640
have been involved in the study for a
997
00:46:26,059 --> 00:46:30,230
long time the studies for six months if
998
00:46:28,639 --> 00:46:33,799
you get results you continue for one
999
00:46:30,230 --> 00:46:35,510
year but as you can see people who are
1000
00:46:33,800 --> 00:46:36,400
done with the stylus keep on using the
1001
00:46:35,510 --> 00:46:38,870
product
1002
00:46:36,400 --> 00:46:39,760
insane even some people who didn't get
1003
00:46:38,869 --> 00:46:42,739
for one reason
1004
00:46:39,760 --> 00:46:45,589
which supposedly progressed end of
1005
00:46:42,739 --> 00:46:48,469
subtitle so it's interesting to read
1006
00:46:45,588 --> 00:46:50,480
like you know if the the first person in
1007
00:46:48,469 --> 00:46:52,189
the last two years I consume because all
1008
00:46:50,480 --> 00:46:54,800
see three times a day I feel energetic
1009
00:46:52,190 --> 00:46:56,269
this good moded appetite the overall
1010
00:46:54,800 --> 00:46:59,480
feeling is much better than the previous
1011
00:46:56,269 --> 00:47:03,289
period Pierce has been stable for 18
1012
00:46:59,480 --> 00:47:06,318
months and interesting but what's
1013
00:47:03,289 --> 00:47:08,239
interesting for us is that it's a
1014
00:47:06,318 --> 00:47:11,029
reflection of this approach of the
1015
00:47:08,239 --> 00:47:13,068
wisdom of nature the decide effect of of
1016
00:47:11,030 --> 00:47:15,440
using something like modified it
1017
00:47:13,068 --> 00:47:17,539
respective for unique to modifies it
1018
00:47:15,440 --> 00:47:21,260
respected and it somebody feels more
1019
00:47:17,539 --> 00:47:23,960
energetic in Goodwood and overall
1020
00:47:21,260 --> 00:47:27,890
feeling is much better the other person
1021
00:47:23,960 --> 00:47:31,130
he took MCT consistently for two years
1022
00:47:27,889 --> 00:47:33,889
and after three months this PSA was
1023
00:47:31,130 --> 00:47:36,440
better and no skin evidence of I mean
1024
00:47:33,889 --> 00:47:38,088
humor until today two years but he said
1025
00:47:36,440 --> 00:47:41,300
I literally feel an improvement in my
1026
00:47:38,088 --> 00:47:44,719
health and fitness feel good stop for
1027
00:47:41,300 --> 00:47:47,660
two months PSA went up and then when it
1028
00:47:44,719 --> 00:47:49,669
restarted it stopped again what's
1029
00:47:47,659 --> 00:47:51,048
interesting about it is this feeling
1030
00:47:49,670 --> 00:47:53,750
good feeling better
1031
00:47:51,048 --> 00:47:56,690
less joint pain better memory better
1032
00:47:53,750 --> 00:47:59,780
mood it all relates to blocking the
1033
00:47:56,690 --> 00:48:02,030
effects of collectings me that's why if
1034
00:47:59,780 --> 00:48:02,750
you look at charts of my patient seven
1035
00:48:02,030 --> 00:48:05,359
eight years ago
1036
00:48:02,750 --> 00:48:06,889
I recommend of course - I said respect
1037
00:48:05,358 --> 00:48:08,750
him but you would not see it at the top
1038
00:48:06,889 --> 00:48:11,900
of the lease it was one of her important
1039
00:48:08,750 --> 00:48:14,239
things I now feel strongly that every
1040
00:48:11,900 --> 00:48:16,579
person needs to take motivated
1041
00:48:14,239 --> 00:48:18,618
respecting because what I started
1042
00:48:16,579 --> 00:48:21,019
respecting is directly related to aging
1043
00:48:18,619 --> 00:48:23,390
into every chronic disease the topic
1044
00:48:21,019 --> 00:48:25,608
today is prostate cancer a budget and
1045
00:48:23,389 --> 00:48:28,578
there that's what we'll focus with the
1046
00:48:25,608 --> 00:48:31,940
dosing but for me it's the number one
1047
00:48:28,579 --> 00:48:33,950
supplement that people need to take so
1048
00:48:31,940 --> 00:48:34,519
if we look at how to use modified citrus
1049
00:48:33,949 --> 00:48:38,929
pectin
1050
00:48:34,519 --> 00:48:41,659
there for people with active prostate
1051
00:48:38,929 --> 00:48:43,848
issues especially cellular issues you
1052
00:48:41,659 --> 00:48:46,368
can use one scoop three times a day or
1053
00:48:43,849 --> 00:48:50,119
one and a half scoops twice a day which
1054
00:48:46,369 --> 00:48:52,068
is equivalent to six capsules or calling
1055
00:48:50,119 --> 00:48:53,329
or Connie to guidance from your own
1056
00:48:52,068 --> 00:48:58,338
health pearl
1057
00:48:53,329 --> 00:49:01,219
petitioner and you can also you can also
1058
00:48:58,338 --> 00:49:03,048
when using depict us or see if using it
1059
00:49:01,219 --> 00:49:05,599
just for prevention from good health
1060
00:49:03,048 --> 00:49:08,088
then five grams is very effective it's
1061
00:49:05,599 --> 00:49:10,910
really useful it's important to
1062
00:49:08,088 --> 00:49:13,548
understand it and good to be taken on
1063
00:49:10,909 --> 00:49:15,129
empty stomach but even 15 20 minutes
1064
00:49:13,548 --> 00:49:17,869
before food is okay
1065
00:49:15,130 --> 00:49:20,209
and if across decades for posted health
1066
00:49:17,869 --> 00:49:22,009
because an active serious condition you
1067
00:49:20,208 --> 00:49:25,848
can go up to six capsules twice a day
1068
00:49:22,009 --> 00:49:27,798
maintenance is two capsules vitally and
1069
00:49:25,849 --> 00:49:30,380
we have published on the synergistic
1070
00:49:27,798 --> 00:49:36,349
effect between poster Kade and pizza
1071
00:49:30,380 --> 00:49:41,390
sauce so to summarize our webinar better
1072
00:49:36,349 --> 00:49:45,440
post a BPH benign prostatic hypertrophy
1073
00:49:41,389 --> 00:49:46,150
and take 50% of men over 50 90 % of men
1074
00:49:45,440 --> 00:49:48,739
over 80
1075
00:49:46,150 --> 00:49:51,318
bps symptoms significantly impact
1076
00:49:48,739 --> 00:49:52,909
quality of slides posted cancer is the
1077
00:49:51,318 --> 00:49:55,518
most common cancer in men we talked a
1078
00:49:52,909 --> 00:49:57,288
little bit a little bit in depths in a
1079
00:49:55,518 --> 00:49:58,758
quick way about a little bit of a
1080
00:49:57,289 --> 00:50:02,028
different way of looking at constant
1081
00:49:58,759 --> 00:50:04,548
concern and we talked to the evidence
1082
00:50:02,028 --> 00:50:07,849
about the benefits of course decade we
1083
00:50:04,548 --> 00:50:13,068
create and manifested respecting so
1084
00:50:07,849 --> 00:50:15,619
important in prostate cancer so I thank
1085
00:50:13,068 --> 00:50:19,038
you very much if you need any questions
1086
00:50:15,619 --> 00:50:20,869
please say please the same to influence
1087
00:50:19,039 --> 00:50:23,509
better publishing I want to think better
1088
00:50:20,869 --> 00:50:25,489
of publishing from hosting me I got
1089
00:50:23,509 --> 00:50:28,159
quite a few questions which I will
1090
00:50:25,489 --> 00:50:29,869
answer may be in writing but one
1091
00:50:28,159 --> 00:50:33,618
question that I got a few of them is
1092
00:50:29,869 --> 00:50:36,798
which I kind of answered is is the use
1093
00:50:33,619 --> 00:50:38,660
of mod affected respecting restricted to
1094
00:50:36,798 --> 00:50:40,670
prostate cancer and the answer is
1095
00:50:38,659 --> 00:50:42,558
obviously not it's not restricted just
1096
00:50:40,670 --> 00:50:44,449
to prostate cancer with evidence
1097
00:50:42,559 --> 00:50:47,059
multiple cancers because of the
1098
00:50:44,449 --> 00:50:49,670
collecting 3 but it really addresses
1099
00:50:47,059 --> 00:50:52,430
inflammation and fibrosis which drives
1100
00:50:49,670 --> 00:50:54,528
chronic disease the other part is does
1101
00:50:52,429 --> 00:50:56,958
modified see prospective remove heavy
1102
00:50:54,528 --> 00:50:58,699
metal it's another question yes if a
1103
00:50:56,958 --> 00:51:00,889
number of clinical trials showing the
1104
00:50:58,699 --> 00:51:03,920
body size in perspective and we move
1105
00:51:00,889 --> 00:51:06,318
heavy metals with late being a leading
1106
00:51:03,920 --> 00:51:08,989
one but also mercury other
1107
00:51:06,318 --> 00:51:11,119
once anyone that now positively charged
1108
00:51:08,989 --> 00:51:16,099
so I want to thank everybody for your
1109
00:51:11,119 --> 00:51:20,509
time and we will after reading after
1110
00:51:16,099 --> 00:51:22,609
reading the questions we'll get back to
1111
00:51:20,509 --> 00:51:25,309
you in writing and I hope to see you or
1112
00:51:22,608 --> 00:51:28,458
hear us out for you to join me again for
1113
00:51:25,309 --> 00:51:31,329
other topics which I hope to offer now
1114
00:51:28,458 --> 00:51:31,328
more frequently
84764
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