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Would you like to inspect the original subtitles? These are the user uploaded subtitles that are being translated: 1 00:00:01,779 --> 00:00:04,014 Freeman: Death will someday come for us all. 2 00:00:04,016 --> 00:00:06,082 [ Thunder crashes ] 3 00:00:06,084 --> 00:00:10,420 But are the dead really gone forever? 4 00:00:10,422 --> 00:00:14,557 Advances in medicine and bold leaps in computer science 5 00:00:14,559 --> 00:00:18,561 may soon allow the dead to walk the earth again... 6 00:00:18,563 --> 00:00:22,632 or survive in some other strange, new form. 7 00:00:22,634 --> 00:00:25,869 Can we resurrect the dead? 8 00:00:31,242 --> 00:00:36,246 Space, time, life itself. 9 00:00:38,149 --> 00:00:43,119 The secrets of the cosmos lie through the wormhole. 10 00:00:43,121 --> 00:00:47,121 ♪ Through the Wormhole 03x06 ♪ Can We Resurrect the Dead? Original Air Date on July 11, 2012 11 00:00:47,146 --> 00:00:51,146 == sync, corrected by elderman == 12 00:00:56,075 --> 00:01:00,245 Death is our ultimate destination, 13 00:01:00,247 --> 00:01:04,249 a place from which no one ever returns. 14 00:01:04,251 --> 00:01:07,452 But what if death was not the end? 15 00:01:07,454 --> 00:01:09,954 We each have a genetic blueprint, 16 00:01:09,956 --> 00:01:12,257 one that science can now read. 17 00:01:12,259 --> 00:01:17,529 Soon, it may be possible to reproduce my body after I die. 18 00:01:17,531 --> 00:01:20,732 But what about the lifetime of knowledge and experience 19 00:01:20,734 --> 00:01:22,834 contained in here? 20 00:01:22,836 --> 00:01:24,736 Will we ever have the tools 21 00:01:24,738 --> 00:01:28,506 to raise body and soul from the dead? 22 00:01:33,145 --> 00:01:38,249 All of us must eventually come face-to-face with death. 23 00:01:38,251 --> 00:01:42,120 No matter how hard we wish to hold on to someone we love, 24 00:01:42,122 --> 00:01:47,225 sometimes, we just have to let go. 25 00:01:47,227 --> 00:01:50,995 I had a dog I loved to go exploring with. 26 00:01:53,566 --> 00:01:54,599 [ Whines ] 27 00:01:54,601 --> 00:01:57,702 But worms had eaten away at his heart. 28 00:02:06,979 --> 00:02:11,649 The pain of saying goodbye forever cuts deep, 29 00:02:11,651 --> 00:02:13,985 but it is unavoidable. 30 00:02:18,257 --> 00:02:20,625 Or is it? 31 00:02:20,627 --> 00:02:22,594 [ Breathes deeply ] 32 00:02:27,066 --> 00:02:29,033 [ Flatline ] 33 00:02:32,504 --> 00:02:35,440 Freeman: This patient is dead. 34 00:02:35,442 --> 00:02:38,576 He has no heartbeat, no respiration, 35 00:02:38,578 --> 00:02:42,080 no blood flowing through his heart. 36 00:02:42,082 --> 00:02:47,785 But today, he will be brought back to life by this man, 37 00:02:47,787 --> 00:02:53,424 heart surgeon John Elefteriades of Yale-New Haven hospital. 38 00:02:53,426 --> 00:02:59,264 John regularly kills his patients, then resurrects them. 39 00:02:59,266 --> 00:03:04,402 Once I got to medical school and residency, 40 00:03:04,404 --> 00:03:06,938 heart surgery was the only thing I ever wanted to do. 41 00:03:06,940 --> 00:03:11,109 At that time, it was kind of like being a fighter pilot 42 00:03:11,111 --> 00:03:13,077 within medicine, if you know what I mean. 43 00:03:13,079 --> 00:03:16,314 It was exploring the frontiers. It was high-risk. 44 00:03:16,316 --> 00:03:21,552 Freeman: John still flies at the edge of the surgical horizon. 45 00:03:23,055 --> 00:03:27,225 Today, he's trying to repair a severely damaged heart, 46 00:03:27,227 --> 00:03:32,230 a heart that can't be fixed while blood flows through it. 47 00:03:34,900 --> 00:03:38,670 The heart must be shut down, but doing so 48 00:03:38,672 --> 00:03:41,472 will cut off the blood supply to the patient's brain, 49 00:03:41,474 --> 00:03:43,841 starving it of oxygen. 50 00:03:46,512 --> 00:03:50,848 John needs 45 minutes to operate. 51 00:03:50,850 --> 00:03:52,383 At normal temperatures, 52 00:03:52,385 --> 00:03:55,453 the brain will begin to die after just five minutes. 53 00:03:57,956 --> 00:04:00,258 John's radical solution 54 00:04:00,260 --> 00:04:04,595 is to freeze the patient into a state of suspended animation. 55 00:04:04,597 --> 00:04:06,898 [ Flatline ] 56 00:04:06,900 --> 00:04:09,000 The brain doesn't tolerate 57 00:04:09,002 --> 00:04:12,737 more than a momentary interruption of blood flow. 58 00:04:12,739 --> 00:04:14,706 If the interruption of blood flow 59 00:04:14,708 --> 00:04:16,274 goes beyond several minutes, 60 00:04:16,276 --> 00:04:18,276 then the brain cells start to die, 61 00:04:18,278 --> 00:04:22,080 and that's where the protection of low temperature 62 00:04:22,082 --> 00:04:24,749 gives us the opportunity to protect 63 00:04:24,751 --> 00:04:26,617 the very vulnerable brain. 64 00:04:26,619 --> 00:04:30,988 Freeman: The patient's warm blood has been drained from his body, 65 00:04:30,990 --> 00:04:34,258 run through a bypass machine filled with ice, 66 00:04:34,260 --> 00:04:38,496 then pumped back through his veins and arteries. 67 00:04:38,498 --> 00:04:42,934 This has gradually cooled him down to 18 degrees Centigrade -- 68 00:04:42,936 --> 00:04:46,604 55 Fahrenheit. 69 00:04:46,606 --> 00:04:52,009 The activity of his cells and neurons cannot be measured. 70 00:04:54,213 --> 00:04:57,281 If you had a general practitioner 71 00:04:57,283 --> 00:05:00,351 or a cardiologist or somebody come in 72 00:05:00,353 --> 00:05:04,188 and use their regular criteria for life or death, 73 00:05:04,190 --> 00:05:06,591 all the criteria for death would be fulfilled. 74 00:05:06,593 --> 00:05:10,828 At this point, the heart-lung machine and the respirator -- 75 00:05:10,830 --> 00:05:14,866 the devices that keep him alive -- are shut off -- 76 00:05:14,868 --> 00:05:18,202 no breathing, no blood pumping -- 77 00:05:18,204 --> 00:05:22,840 a condition virtually identical to death. 78 00:05:22,842 --> 00:05:24,742 [ Flatline ] 79 00:05:25,878 --> 00:05:29,881 John has 45 minutes to operate in safety. 80 00:05:29,883 --> 00:05:33,384 After an hour, brain damage will set in. 81 00:05:33,386 --> 00:05:37,121 Now his decades of experience come into play. 82 00:05:37,123 --> 00:05:40,425 We're still in suspended animation. 83 00:05:43,429 --> 00:05:46,597 So we've got 15 minutes to go for safety. 84 00:05:48,434 --> 00:05:50,101 Freeman: Finally, 85 00:05:50,103 --> 00:05:52,870 John and his team manage to complete the repairs 86 00:05:52,872 --> 00:05:55,440 with seven minutes to spare. 87 00:05:55,442 --> 00:05:59,877 The patient has been virtually dead for 38 minutes. 88 00:05:59,879 --> 00:06:02,880 They slowly bring back life support, 89 00:06:02,882 --> 00:06:04,982 returning him to the land of the living with 90 00:06:04,984 --> 00:06:07,618 no damage to the brain. 91 00:06:11,190 --> 00:06:15,293 Each and every day, I'm amazed that this can be done. 92 00:06:15,295 --> 00:06:18,830 The definition of death has changed, really, 93 00:06:18,832 --> 00:06:21,265 and death is death when it's permanent. 94 00:06:21,267 --> 00:06:22,567 But those criteria 95 00:06:22,569 --> 00:06:26,938 in this very, very special high-technology scenario 96 00:06:26,940 --> 00:06:30,107 of suspended animation or deep hypothermic arrest -- 97 00:06:30,109 --> 00:06:32,944 those criteria for death don't really apply. 98 00:06:32,946 --> 00:06:35,913 Freeman: But can we bring life back 99 00:06:35,915 --> 00:06:39,550 to those who die in less controlled situations? 100 00:06:39,552 --> 00:06:42,019 [ Thunder crashes ] 101 00:06:45,691 --> 00:06:48,893 Lance Becker is the director of the University of Pennsylvania's 102 00:06:48,895 --> 00:06:51,929 Center for Resuscitation Science. 103 00:06:51,931 --> 00:06:55,066 He believes the key to resurrection 104 00:06:55,068 --> 00:06:57,735 is buried deep within our cells. 105 00:06:57,737 --> 00:07:01,739 Well, what we've known for just literally thousands of years 106 00:07:01,741 --> 00:07:07,011 is that, if you keep meat cold, it keeps longer. 107 00:07:07,013 --> 00:07:11,182 The decay process, which is actually that death process -- 108 00:07:11,184 --> 00:07:16,053 [slowly] All of those things are slowed down 109 00:07:16,055 --> 00:07:18,122 in the cold setting. 110 00:07:18,124 --> 00:07:19,790 [ Normal voice ] When the temperature comes down, 111 00:07:19,792 --> 00:07:21,826 the cells don't need as much oxygen, 112 00:07:21,828 --> 00:07:25,296 they don't metabolize as much, 113 00:07:25,298 --> 00:07:31,402 and they essentially sort of go into slow-mo, hibernation-style. 114 00:07:33,105 --> 00:07:38,643 Freeman: Your body is made of tens of trillions of living cells. 115 00:07:38,645 --> 00:07:42,847 Regulatory genes tell these cells how to behave. 116 00:07:42,849 --> 00:07:46,851 Think of them as the cells' operating system. 117 00:07:46,853 --> 00:07:50,221 At the end of a cell's life, the genes produce 118 00:07:50,223 --> 00:07:53,691 destructive enzymes that tear the cell apart. 119 00:07:53,693 --> 00:07:59,530 Every day, roughly 50 billion of your cells die. 120 00:08:01,600 --> 00:08:04,101 When something goes very wrong -- 121 00:08:04,103 --> 00:08:07,605 say, you suffer a cardiac arrest -- 122 00:08:07,607 --> 00:08:11,108 the injured cells sound an alarm, 123 00:08:11,110 --> 00:08:16,047 telling their healthy neighbors it's time to die. 124 00:08:16,049 --> 00:08:18,983 This sets off a wave of cellular suicide 125 00:08:18,985 --> 00:08:21,819 that spreads rapidly across the body. 126 00:08:22,888 --> 00:08:26,424 We don't die by accident. 127 00:08:26,426 --> 00:08:31,862 There's biological programming 128 00:08:31,864 --> 00:08:36,167 that actually controls the way we die. 129 00:08:36,169 --> 00:08:38,569 And in that programming 130 00:08:38,571 --> 00:08:42,873 is the opportunity for modifying that program 131 00:08:42,875 --> 00:08:45,843 so that we can alter the outcome -- 132 00:08:45,845 --> 00:08:47,545 bring someone back to life. 133 00:08:47,547 --> 00:08:51,415 Freeman: To find out what triggers the death program, 134 00:08:51,417 --> 00:08:55,920 Lance took healthy cells and starved them of oxygen. 135 00:08:55,922 --> 00:08:59,857 He expected most of the cells to die 136 00:08:59,859 --> 00:09:05,096 and the survivors to flourish when oxygen was restored. 137 00:09:05,098 --> 00:09:06,497 Dr. Becker: So, what I found 138 00:09:06,499 --> 00:09:10,134 was the opposite of what we thought we would find, 139 00:09:10,136 --> 00:09:12,403 which is the cells without oxygen 140 00:09:12,405 --> 00:09:15,006 just sort of laid there. 141 00:09:15,008 --> 00:09:18,643 They didn't do anything, but they didn't die. 142 00:09:18,645 --> 00:09:22,780 But what happened was, when we reoxygenated those cells, 143 00:09:22,782 --> 00:09:25,650 that's when cell death occurred. 144 00:09:25,652 --> 00:09:27,885 So it is a little bit ironic 145 00:09:27,887 --> 00:09:32,990 that oxygen, the molecule that we love and that we live with, 146 00:09:32,992 --> 00:09:37,228 becomes the molecule that drives death. 147 00:09:37,230 --> 00:09:42,099 Freeman: Somehow, reintroducing oxygen into cells 148 00:09:42,101 --> 00:09:44,435 triggers the death signal 149 00:09:44,437 --> 00:09:47,538 that causes them to commit mass suicide. 150 00:09:47,540 --> 00:09:48,739 [ Grunting ] 151 00:09:48,741 --> 00:09:52,410 Freezing seems to interrupt this process. 152 00:09:52,412 --> 00:09:54,245 Lance pressed on, 153 00:09:54,247 --> 00:09:57,548 knowing that, if he found the death signal's source, 154 00:09:57,550 --> 00:10:00,451 he might be able to stop it from transmitting 155 00:10:00,453 --> 00:10:03,320 without the need for freezing. 156 00:10:03,322 --> 00:10:05,356 As we began to ask ourselves, 157 00:10:05,358 --> 00:10:08,926 "What could explain this sort of bizarre behavior?" 158 00:10:08,928 --> 00:10:12,229 We started seeing cellular pathways. 159 00:10:12,231 --> 00:10:17,168 All of the paths led us to the organelle inside our cells 160 00:10:17,170 --> 00:10:19,770 that we call the mitochondria. 161 00:10:21,440 --> 00:10:26,977 Freeman: Mitochondria lie deep within every single cell of your body. 162 00:10:26,979 --> 00:10:30,514 They take the food you eat and the oxygen you breathe 163 00:10:30,516 --> 00:10:33,984 and convert them into chemical energy. 164 00:10:33,986 --> 00:10:39,623 Dr. Becker: In some ways, it's a little bit like a nuclear power plant. 165 00:10:39,625 --> 00:10:42,059 And you know how, in a nuclear power plant, 166 00:10:42,061 --> 00:10:45,496 there are rods that come together and they produce the heat, 167 00:10:45,498 --> 00:10:47,231 and if you don't control that process, 168 00:10:47,233 --> 00:10:49,900 you end up with Chernobyl. 169 00:10:49,902 --> 00:10:54,739 What happens is, after one mitochondria goes nuclear, 170 00:10:54,741 --> 00:10:57,908 it starts to trigger a chain reaction 171 00:10:57,910 --> 00:11:00,411 that amplifies the death signal, 172 00:11:00,413 --> 00:11:04,648 and that death signal can be spread throughout the body. 173 00:11:04,650 --> 00:11:05,716 [ Gags ] 174 00:11:05,718 --> 00:11:08,853 Freeman: Lance and his team suspect 175 00:11:08,855 --> 00:11:12,656 we might be able to stop this chain reaction 176 00:11:12,658 --> 00:11:15,092 by poisoning our mitochondria 177 00:11:15,094 --> 00:11:19,430 with sulfide, cyanide, and carbon monoxide. 178 00:11:19,432 --> 00:11:22,466 A finely calibrated dose of these toxins 179 00:11:22,468 --> 00:11:24,235 might disarm the death signal. 180 00:11:24,237 --> 00:11:26,370 It will be quicker than freezing, 181 00:11:26,372 --> 00:11:30,341 and it could reverse a cellular meltdown. 182 00:11:33,011 --> 00:11:35,412 So, ideally, what we'd like to do 183 00:11:35,414 --> 00:11:39,083 is we'd like to get a few of those molecules on board 184 00:11:39,085 --> 00:11:42,353 as we're beginning to bring oxygen back to the patient. 185 00:11:42,355 --> 00:11:45,556 We think we can restart that mitochondria, 186 00:11:45,558 --> 00:11:49,627 have it convert back to producing energy 187 00:11:49,629 --> 00:11:53,464 instead of producing death. 188 00:11:53,466 --> 00:11:56,734 Freeman: These treatments are still highly experimental. 189 00:11:56,736 --> 00:12:00,204 But if doctors can silence the death signal, 190 00:12:00,206 --> 00:12:02,373 it may soon be commonplace 191 00:12:02,375 --> 00:12:05,910 to revive the dying and the recently dead. 192 00:12:05,912 --> 00:12:06,944 [ Thunder crashes ] 193 00:12:06,946 --> 00:12:09,180 Medical science has already proven 194 00:12:09,182 --> 00:12:10,915 that the dead can live again 195 00:12:10,917 --> 00:12:14,819 under a very controlled set of circumstances. 196 00:12:14,821 --> 00:12:17,087 But can it take us further? 197 00:12:18,290 --> 00:12:21,392 What if we could grow the dead back to life? 198 00:12:23,423 --> 00:12:26,091 Imagine how much richer humanity might be 199 00:12:27,084 --> 00:12:31,120 if we could raise Einstein or Mozart from the grave 200 00:12:31,122 --> 00:12:34,523 or how much it would mean to us personally 201 00:12:34,525 --> 00:12:38,794 if we could bring back the loved ones we have lost? 202 00:12:41,064 --> 00:12:43,632 It may be possible. 203 00:12:43,634 --> 00:12:48,337 Cloning has opened up a new road to resurrection... 204 00:12:48,339 --> 00:12:50,739 But should we take it? 205 00:12:52,208 --> 00:12:56,946 Bob Lanza was born into a working-class Boston family. 206 00:12:56,948 --> 00:12:59,915 Today, he owns an island in Massachusetts 207 00:12:59,917 --> 00:13:02,384 and lives in a sprawling compound 208 00:13:02,386 --> 00:13:06,355 that's part house, part natural-history museum. 209 00:13:06,357 --> 00:13:11,427 These are the fruits of a career in biotechnology. 210 00:13:11,429 --> 00:13:13,862 Lanza: Here's a brontosaurus femur. 211 00:13:13,864 --> 00:13:16,098 One of the first things people ask me when they come into the house 212 00:13:16,100 --> 00:13:17,866 is, "Bob, are you gonna clone that?" 213 00:13:17,868 --> 00:13:19,969 And I tell them, "you can't clone from stone. 214 00:13:19,971 --> 00:13:21,103 You need a living cell." 215 00:13:21,105 --> 00:13:24,740 Freeman: Over the last decade, 216 00:13:24,742 --> 00:13:29,878 Bob has successfully cloned mice, cows, cats, dogs, 217 00:13:29,880 --> 00:13:33,549 pigs, sheep, and horses. 218 00:13:33,551 --> 00:13:37,886 In 2001, he used frozen cells to successfully resurrect 219 00:13:37,888 --> 00:13:42,958 an extinct southeast Asian ox called a Gaur, 220 00:13:42,960 --> 00:13:47,196 using an American cow as a surrogate mother. 221 00:13:47,198 --> 00:13:48,731 Everyone said, "no, that won't work. 222 00:13:48,733 --> 00:13:51,066 You can't clone one species using the egg from another one." 223 00:13:51,068 --> 00:13:53,235 And I said, "no, no, no. If we do it and it's close enough, 224 00:13:53,237 --> 00:13:54,436 we should get it to work." 225 00:13:54,438 --> 00:13:56,538 So I actually took skin cells from the Gaur, 226 00:13:56,540 --> 00:13:59,441 and I actually put the DNA into an ordinary cow egg. 227 00:13:59,443 --> 00:14:02,611 And then we created these spectacular little Gaur embryos, 228 00:14:02,613 --> 00:14:04,680 and we shipped them off to Iowa, 229 00:14:04,682 --> 00:14:07,016 where they were implanted into an ordinary cow. 230 00:14:07,018 --> 00:14:08,784 And it turns out that, 10 months later, 231 00:14:08,786 --> 00:14:12,021 we had this beautiful little baby Gaur that was born. 232 00:14:12,023 --> 00:14:14,456 It looked like a little baby reindeer -- just adorable. 233 00:14:14,458 --> 00:14:19,995 Freeman: But where Bob sees beauty, others see monstrosity. 234 00:14:19,997 --> 00:14:23,799 Opponents of cloning say he's playing God. 235 00:14:23,801 --> 00:14:26,735 Bob doesn't see it that way. 236 00:14:26,737 --> 00:14:29,304 Cloning really isn't all that unusual. 237 00:14:29,306 --> 00:14:32,441 For thousands of years, people have been cloning plants. 238 00:14:32,443 --> 00:14:35,744 You can actually start by taking a clipping from a plant -- 239 00:14:35,746 --> 00:14:38,514 you get some of the genetic material -- 240 00:14:38,516 --> 00:14:42,184 and then add a little nutrients... 241 00:14:44,387 --> 00:14:45,621 ...get it to root, 242 00:14:45,623 --> 00:14:49,224 and to basically clone an entire new organism. 243 00:14:50,560 --> 00:14:54,063 Freeman: Humanity has mastered the cloning of plants, 244 00:14:54,065 --> 00:14:57,699 and we are now working our way through the animal kingdom. 245 00:14:57,701 --> 00:15:00,869 Could we someday take the DNA of dead people 246 00:15:00,871 --> 00:15:03,038 and bring their bodies back to life? 247 00:15:03,040 --> 00:15:06,942 Can we cultivate a garden of resurrected humans? 248 00:15:06,944 --> 00:15:09,745 [ Owl hooting ] 249 00:15:09,747 --> 00:15:11,747 Imagine a world 250 00:15:11,749 --> 00:15:14,583 where a woman could bring back her deceased husband 251 00:15:14,585 --> 00:15:16,919 by giving birth to him... 252 00:15:16,921 --> 00:15:19,088 or a man could bring back his mother 253 00:15:19,090 --> 00:15:21,890 and raise her as his daughter. 254 00:15:21,892 --> 00:15:24,893 If we have a living cell of a dead person, 255 00:15:24,895 --> 00:15:28,263 certainly, we could, in theory, clone that individual. 256 00:15:28,265 --> 00:15:31,100 We published a paper about a year or two ago 257 00:15:31,102 --> 00:15:34,470 where we show we can actually now create human embryos 258 00:15:34,472 --> 00:15:38,207 that are genetically identical to a normal embryo. 259 00:15:38,209 --> 00:15:40,209 The only way you would really know 260 00:15:40,211 --> 00:15:42,344 whether you could clone a human being 261 00:15:42,346 --> 00:15:44,346 is to actually implant that embryo 262 00:15:44,348 --> 00:15:46,515 into the uterus of a surrogate mother. 263 00:15:46,517 --> 00:15:47,983 Of course, we cannot implant those -- 264 00:15:47,985 --> 00:15:49,418 that would be considered unethical -- 265 00:15:49,420 --> 00:15:51,086 so it's unclear whether or not they would -- 266 00:15:51,088 --> 00:15:52,321 would give rise to a human being. 267 00:15:53,656 --> 00:15:59,628 Freeman: Society has vehemently rejected reproductive human cloning. 268 00:15:59,630 --> 00:16:02,831 In this climate, it is extremely difficult 269 00:16:02,833 --> 00:16:07,369 for geneticists to obtain funding for their research. 270 00:16:07,371 --> 00:16:10,239 There is also a shortage of material. 271 00:16:10,241 --> 00:16:12,574 Lanza: So, one of the problems with human cloning 272 00:16:12,576 --> 00:16:13,675 is the supply of eggs. 273 00:16:13,677 --> 00:16:15,077 So, with a mouse or a cow, 274 00:16:15,079 --> 00:16:17,913 we can get literally hundreds, if not thousands, of eggs. 275 00:16:17,915 --> 00:16:19,915 We can go to the slaughterhouse, for instance, 276 00:16:19,917 --> 00:16:21,216 and get them for a dollar each 277 00:16:21,218 --> 00:16:22,851 and get thousands of these cow eggs. 278 00:16:22,853 --> 00:16:26,822 With the humans, it took us over a year just to get five eggs. 279 00:16:26,824 --> 00:16:29,124 Freeman: Even if you had the eggs, 280 00:16:29,126 --> 00:16:31,527 it could take hundreds of pregnancies 281 00:16:31,529 --> 00:16:34,096 to perfect human cloning, 282 00:16:34,098 --> 00:16:35,531 a process that could result 283 00:16:35,533 --> 00:16:39,935 in scores of babies with horrific genetic damage. 284 00:16:39,937 --> 00:16:41,236 Lanza: It'd be very much like -- 285 00:16:41,238 --> 00:16:43,238 if you wanted to clone your child, 286 00:16:43,240 --> 00:16:45,274 it'd be like sending him up in a rocket 287 00:16:45,276 --> 00:16:47,176 with a 50-50 chance it would blow up. 288 00:16:47,178 --> 00:16:52,481 Freeman: In most of the world, cloning humans is not illegal. 289 00:16:52,483 --> 00:16:57,753 One day, a rogue scientist will pull it off. 290 00:16:57,755 --> 00:17:04,293 But cloning a person is not the same as duplicating a person. 291 00:17:06,863 --> 00:17:09,431 Lanza: A lot of people, you know, who have their pets -- 292 00:17:09,433 --> 00:17:12,034 they want to often clone them, and they want Fluffy back. 293 00:17:12,036 --> 00:17:14,570 And what I tell them is, "you're not gonna get Fluffy back." 294 00:17:14,572 --> 00:17:17,639 As a matter of fact, we actually clone entire herds of cows 295 00:17:17,641 --> 00:17:19,875 from a single cell from the same animal, 296 00:17:19,877 --> 00:17:21,810 and they develop a whole hierarchy, 297 00:17:21,812 --> 00:17:23,212 just like we do in humans. 298 00:17:23,214 --> 00:17:25,514 So you have timid cows and aggressive cows, 299 00:17:25,516 --> 00:17:26,748 and they're all clones. 300 00:17:26,750 --> 00:17:29,084 So they develop their own behavioral patters. 301 00:17:29,086 --> 00:17:30,319 So the environment 302 00:17:30,321 --> 00:17:33,922 has a very profound impact on your development. 303 00:17:33,924 --> 00:17:38,961 Freeman: Let's say we decide to take DNA from Einstein's hair 304 00:17:38,963 --> 00:17:42,030 and grow some new Einsteins. 305 00:17:42,032 --> 00:17:47,336 Those clones would not be the man who wrote "E = MC squared." 306 00:17:47,338 --> 00:17:49,805 Each would have a unique personality 307 00:17:49,807 --> 00:17:52,040 shaped by his environment. 308 00:17:52,042 --> 00:17:53,508 [ Cellphone rings ] [ Speaking indistinctly ] 309 00:17:53,510 --> 00:17:59,014 Clones are like identical twins born years apart -- 310 00:17:59,016 --> 00:18:04,953 they may be similar, but they will not be the same. 311 00:18:04,955 --> 00:18:07,689 Perhaps the key to life after death 312 00:18:07,691 --> 00:18:10,425 is not to grow an entirely new body, 313 00:18:10,427 --> 00:18:12,527 but to resurrect the one you have. 314 00:18:16,580 --> 00:18:19,982 At the moment, our society does not permit human cloning, 315 00:18:21,860 --> 00:18:23,827 but that could change. 316 00:18:23,829 --> 00:18:25,562 In the meantime, 317 00:18:25,564 --> 00:18:29,799 biotechnologists have another trick up their sleeves -- 318 00:18:29,801 --> 00:18:33,636 resurrecting people piece by piece. 319 00:18:33,638 --> 00:18:37,707 It's an approach that could transform medical science 320 00:18:37,709 --> 00:18:42,612 and blur the line between life and death. 321 00:18:42,614 --> 00:18:45,749 The revolution begins here, 322 00:18:45,751 --> 00:18:48,918 in a laboratory the University of Minnesota. 323 00:18:48,920 --> 00:18:52,288 This is where Dr. Doris Taylor 324 00:18:52,290 --> 00:18:55,492 breathes life back into the dead. 325 00:18:55,494 --> 00:18:57,861 Dr. Taylor: I just want to change the world. 326 00:18:57,863 --> 00:19:00,563 I want to change the world for people with disease. 327 00:19:00,565 --> 00:19:03,400 I also have a brother who's chronically ill, 328 00:19:03,402 --> 00:19:07,270 and that's probably influenced everything I've done in my life. 329 00:19:07,272 --> 00:19:11,274 Tipler: Doris is changing the world by growing new body parts 330 00:19:11,276 --> 00:19:13,543 from the shells of old ones. 331 00:19:13,545 --> 00:19:17,614 She takes organs from cadavers and reanimates them 332 00:19:17,616 --> 00:19:23,219 using a method drawn from an unlikely source -- architecture. 333 00:19:28,859 --> 00:19:30,527 Dr. Taylor: The bricks in a building 334 00:19:30,529 --> 00:19:33,029 are just like the cells in an organ -- 335 00:19:33,031 --> 00:19:35,298 different kinds, different shapes. 336 00:19:35,300 --> 00:19:36,800 And they make rooms, 337 00:19:36,802 --> 00:19:40,170 and the rooms are like the chambers of a heart. 338 00:19:40,172 --> 00:19:43,673 They're connected by doorways, like the valves. 339 00:19:43,675 --> 00:19:46,376 They have hallways, like the arteries and veins. 340 00:19:46,378 --> 00:19:49,379 Essentially, you can think of an organ 341 00:19:49,381 --> 00:19:51,881 just like you think of a building. 342 00:19:52,817 --> 00:19:57,053 Freeman: Just as buildings can be rebuilt brick by brick, 343 00:19:57,055 --> 00:20:01,758 Doris believes bodies can be rebuilt cell by cell. 344 00:20:01,760 --> 00:20:05,361 In building construction, they use a scaffold that -- 345 00:20:05,363 --> 00:20:06,863 like you see here -- 346 00:20:06,865 --> 00:20:12,068 to essentially provide access to otherwise inaccessible areas 347 00:20:12,070 --> 00:20:15,672 and to create a framework for what they're gonna build. 348 00:20:15,674 --> 00:20:19,509 We essentially do the same thing in the laboratory with an organ. 349 00:20:19,511 --> 00:20:22,479 We create a framework on which we can put cells. 350 00:20:22,481 --> 00:20:27,517 Freeman: Doris reanimates major organs, 351 00:20:27,519 --> 00:20:31,488 including livers, lungs, and hearts. 352 00:20:34,091 --> 00:20:36,493 Dr. Taylor: This is a ghost heart. 353 00:20:36,495 --> 00:20:40,029 This is essentially the framework, or scaffold, 354 00:20:40,031 --> 00:20:41,898 on which the cells sit. 355 00:20:41,900 --> 00:20:45,001 And by washing out all the cells, 356 00:20:45,003 --> 00:20:47,704 what we have left is a scaffold 357 00:20:47,706 --> 00:20:52,742 that we can repopulate with cells to now build a new organ. 358 00:20:52,744 --> 00:20:56,779 So, essentially, this scaffold is what tells cells 359 00:20:56,781 --> 00:21:00,149 how to join together and become a heart. 360 00:21:02,353 --> 00:21:04,854 Freeman: What happens when you put fresh cells 361 00:21:04,856 --> 00:21:07,857 into a decellularized heart? 362 00:21:09,293 --> 00:21:13,296 This -- a modern miracle. 363 00:21:14,331 --> 00:21:17,100 Right now, if you need a body part, 364 00:21:17,102 --> 00:21:20,537 you face the grim prospect of organ rejection, 365 00:21:20,539 --> 00:21:25,708 but Doris' replacement organs -- heart, kidneys, and livers -- 366 00:21:25,710 --> 00:21:28,878 will be tailor-made for your body. 367 00:21:28,880 --> 00:21:33,516 We'll take an organ from a pig, strip all the cells, 368 00:21:33,518 --> 00:21:36,519 take your stem cells, put them in that organ, 369 00:21:36,521 --> 00:21:39,088 and build something that matches you. 370 00:21:39,090 --> 00:21:41,791 Freeman: So, if Doris and her team 371 00:21:41,793 --> 00:21:44,928 can bring hearts and livers back from the dead, 372 00:21:44,930 --> 00:21:48,598 could they also reanimate a human brain? 373 00:21:48,600 --> 00:21:53,202 Dr. Taylor: Now, could we build a cluster of neurons 374 00:21:53,204 --> 00:21:54,671 and glial cells 375 00:21:54,673 --> 00:21:58,575 and everything that looks like part of a brain or a brain? 376 00:21:58,577 --> 00:22:02,612 I have no doubt that, one day, we'll be able to do that. 377 00:22:02,614 --> 00:22:08,585 Can we resurrect you and who you are -- your personality? 378 00:22:08,587 --> 00:22:11,321 I don't think we know how to do that yet. 379 00:22:11,323 --> 00:22:15,158 Freeman: It's more likely this technology will be used 380 00:22:15,160 --> 00:22:17,994 to replace damaged sections of the brain, 381 00:22:17,996 --> 00:22:22,398 perhaps even extending its life beyond the rest of the body. 382 00:22:22,400 --> 00:22:26,402 [ Thunder crashing ] But can we go even further? 383 00:22:26,404 --> 00:22:31,040 As we die, could we have our brains transplanted 384 00:22:31,042 --> 00:22:34,177 into healthy donor bodies? 385 00:22:34,179 --> 00:22:36,412 [ Thunder crashes ] 386 00:22:36,414 --> 00:22:40,583 I suspect the biggest challenge to a brain transplant 387 00:22:40,585 --> 00:22:43,620 is keeping it alive 388 00:22:43,622 --> 00:22:49,759 during the time of removing it from an individual 389 00:22:49,761 --> 00:22:54,297 and all the connections that would have to be recapitulated 390 00:22:54,299 --> 00:22:56,499 in a transplanted individual, 391 00:22:56,501 --> 00:22:58,368 because unlike the heart, 392 00:22:58,370 --> 00:23:00,370 it's not just about hooking up the blood supply. 393 00:23:00,372 --> 00:23:04,674 It'd also be about hooking up the spinal cord, 394 00:23:04,676 --> 00:23:07,110 hooking up all the nerves. 395 00:23:07,112 --> 00:23:12,148 I can't imagine how we could make all those connections 396 00:23:12,150 --> 00:23:16,185 in a timely way that maintain function. 397 00:23:16,187 --> 00:23:20,923 Freeman: But do we even need to have physical brains? 398 00:23:22,359 --> 00:23:24,761 The key to resurrection 399 00:23:24,763 --> 00:23:28,431 is to restore what fundamentally makes us unique -- 400 00:23:28,433 --> 00:23:31,401 the contents of our minds. 401 00:23:31,403 --> 00:23:35,571 As technology advances, the prospect of copying our brains 402 00:23:35,573 --> 00:23:38,041 becomes more and more likely. 403 00:23:38,043 --> 00:23:42,011 Bringing the dead back to life may just be a matter 404 00:23:42,013 --> 00:23:46,115 of combining the right zeroes and ones. 405 00:23:49,997 --> 00:23:53,366 Our lives are continually monitored by technology. 406 00:23:54,801 --> 00:23:59,638 Almost everything we do leaves a digital trail. 407 00:23:59,640 --> 00:24:02,173 This immense library of information 408 00:24:02,175 --> 00:24:05,577 may still exist long after we die. 409 00:24:05,579 --> 00:24:10,248 If we gathered up a lifetime of these digital footprints, 410 00:24:10,250 --> 00:24:15,253 could we use them to bring someone back from the dead? 411 00:24:20,393 --> 00:24:21,860 These students 412 00:24:21,862 --> 00:24:25,630 could be the first humans to rise from the dead. 413 00:24:25,632 --> 00:24:30,001 They call themselves extreme lifeloggers. 414 00:24:30,003 --> 00:24:34,906 And they are digitally archiving their existence. 415 00:24:36,175 --> 00:24:40,812 Everything they see and hear, wherever they go, 416 00:24:40,814 --> 00:24:44,316 whomever they are with, how fast their hearts beat, 417 00:24:44,318 --> 00:24:46,685 even how much they sweat -- 418 00:24:46,687 --> 00:24:50,021 it's all recorded onto hard drives 419 00:24:50,023 --> 00:24:52,324 at Dublin City University. 420 00:24:52,326 --> 00:24:53,491 This is the brainchild 421 00:24:53,493 --> 00:24:58,263 of search-engine specialist Cathal Gurrin. 422 00:24:58,265 --> 00:25:00,632 Hey, how did it go? Pretty well. 423 00:25:00,634 --> 00:25:01,866 Woman: It was fun. 424 00:25:01,868 --> 00:25:03,935 How about the weather -- was it cold? Bit cold. 425 00:25:03,937 --> 00:25:06,071 You got the devices. We can have a look? Yes. 426 00:25:06,073 --> 00:25:08,540 Accelerometer. Yes, accelerometer. 427 00:25:08,542 --> 00:25:10,275 Here is mine. Oh, thank you. 428 00:25:10,277 --> 00:25:12,210 And the camera. Camera. Great. 429 00:25:12,212 --> 00:25:13,945 Thanks. Let's have a look. 430 00:25:13,947 --> 00:25:19,284 Freeman: Cathal has recorded his own life for 5 1/2 years. 431 00:25:19,286 --> 00:25:21,553 So far, he has gathered 432 00:25:21,555 --> 00:25:26,458 over 8 1/2 million images and sensor readings. 433 00:25:26,460 --> 00:25:29,127 So here's, for example, a typical day in my life -- 434 00:25:29,129 --> 00:25:30,395 on the 10th of November. 435 00:25:30,397 --> 00:25:32,731 Here you can see what I did on that day. 436 00:25:32,733 --> 00:25:35,166 I got up in the morning. I made breakfast. 437 00:25:35,168 --> 00:25:36,401 I went to my office. 438 00:25:36,403 --> 00:25:39,504 I worked pretty much all of the day, with a coffee break, 439 00:25:39,506 --> 00:25:41,239 and then, driving home at night, 440 00:25:41,241 --> 00:25:43,174 going by a restaurant on the way. 441 00:25:43,176 --> 00:25:44,509 The software we have 442 00:25:44,511 --> 00:25:48,480 has managed to take about 3,000 pictures on that day 443 00:25:48,482 --> 00:25:50,281 and summarized them down 444 00:25:50,283 --> 00:25:52,584 into this collection of about 30 pictures. 445 00:25:52,586 --> 00:25:57,689 Freeman: Cathal is creating an auxiliary memory -- 446 00:25:57,691 --> 00:25:59,557 something that can be searched 447 00:25:59,559 --> 00:26:02,527 when his biological memory fails him, 448 00:26:02,529 --> 00:26:08,933 preserved in a medium far more accurate than the human brain. 449 00:26:08,935 --> 00:26:10,802 When you're faced with this kind of data 450 00:26:10,804 --> 00:26:12,737 about your life -- your life in the past -- 451 00:26:12,739 --> 00:26:15,740 then you start to identify times you make mistakes in your memory. 452 00:26:15,742 --> 00:26:16,875 It becomes very apparent 453 00:26:16,877 --> 00:26:18,676 when you remember an event in the past 454 00:26:18,678 --> 00:26:21,479 and you go back to look at it -- the differences in the reality 455 00:26:21,481 --> 00:26:23,214 versus what you actually see itself. 456 00:26:23,216 --> 00:26:25,383 And that's where a life log can really help you 457 00:26:25,385 --> 00:26:27,886 to identify the truth about what's happened in the past, 458 00:26:27,888 --> 00:26:29,654 not just your memory's version of it, 459 00:26:29,656 --> 00:26:32,690 which we know, from research, that we'll have inaccuracies -- 460 00:26:32,692 --> 00:26:34,626 we'll have flaws in that memory. 461 00:26:36,228 --> 00:26:39,798 Freeman: Anyone who's spent time on social-networking sites 462 00:26:39,800 --> 00:26:42,066 knows that a basic form of lifelogging 463 00:26:42,068 --> 00:26:45,670 is already practiced by millions of people, 464 00:26:45,672 --> 00:26:48,640 anxious to share their every passing thought, 465 00:26:48,642 --> 00:26:50,742 no matter how trivial. 466 00:26:50,744 --> 00:26:53,311 It's estimated 467 00:26:53,313 --> 00:26:57,382 that humanity today generates more data in two days 468 00:26:57,384 --> 00:27:03,855 than it produced in all of history up to the year 2003. 469 00:27:03,857 --> 00:27:08,493 And this data stream is expected to increase exponentially 470 00:27:08,495 --> 00:27:09,894 in the future. 471 00:27:09,896 --> 00:27:11,863 Extreme lifelogging will add 472 00:27:11,865 --> 00:27:14,399 an enormous amount of new imagery and data 473 00:27:14,401 --> 00:27:18,837 to the vast amount that already floods the Internet. 474 00:27:18,839 --> 00:27:20,371 Gurrin: We will typically capture 475 00:27:20,373 --> 00:27:23,041 at least a million photographs a year for an individual person. 476 00:27:23,043 --> 00:27:25,109 So that's an incredibly huge data set 477 00:27:25,111 --> 00:27:27,011 to be handled by a search engine. 478 00:27:27,013 --> 00:27:29,481 And that's one of the issues about lifelogging 479 00:27:29,483 --> 00:27:31,983 that we are trying to solve in this research -- 480 00:27:31,985 --> 00:27:34,486 how to handle a million photographs a year for people, 481 00:27:34,488 --> 00:27:37,121 how to handle many hundreds of millions of sensor values, 482 00:27:37,123 --> 00:27:40,291 make sense of this, organize this, 483 00:27:40,293 --> 00:27:43,495 and take this enormous quantity of big, big data about people 484 00:27:43,497 --> 00:27:47,799 and make it useable and easy for the people 485 00:27:47,801 --> 00:27:50,268 to access their content from within that archive. 486 00:27:50,270 --> 00:27:52,370 Freeman: Cathal and his students 487 00:27:52,372 --> 00:27:54,272 are creating backup drives 488 00:27:54,274 --> 00:27:57,976 for their entire life's experience -- 489 00:27:57,978 --> 00:28:00,945 black boxes of the mind. 490 00:28:00,947 --> 00:28:05,517 Someday, we might all have these personal life recorders -- 491 00:28:05,519 --> 00:28:08,253 initially, to enhance our memories, 492 00:28:08,255 --> 00:28:13,358 but after death, our survivors could take our black boxes 493 00:28:13,360 --> 00:28:17,028 and hand them over for uploading. 494 00:28:17,030 --> 00:28:18,963 Gurrin: Essentially, memory defines us. 495 00:28:18,965 --> 00:28:20,598 A person's personality is based 496 00:28:20,600 --> 00:28:22,967 on their memories and their experiences over time. 497 00:28:22,969 --> 00:28:25,103 By gathering all this type of data, 498 00:28:25,105 --> 00:28:27,939 we're able to hopefully, in the future, re-create 499 00:28:27,941 --> 00:28:30,742 that person's personality in the digital memory. 500 00:28:30,744 --> 00:28:32,677 We're able to re-create how that person reacts 501 00:28:32,679 --> 00:28:34,412 to a certain stimulus in the environment, 502 00:28:34,414 --> 00:28:36,714 how that person reacts to interactions with other people. 503 00:28:36,716 --> 00:28:38,983 We'd be able to take the digital memory data 504 00:28:38,985 --> 00:28:41,252 and by enhancing our artificial-intelligence 505 00:28:41,254 --> 00:28:43,354 algorithms and search engines right now, 506 00:28:43,356 --> 00:28:44,756 be able to re-create 507 00:28:44,758 --> 00:28:47,792 a fairly good representation of that person's personality 508 00:28:47,794 --> 00:28:49,260 from the digital memory. 509 00:28:49,262 --> 00:28:53,631 Freeman: This would not create a perfect mirror of the mind, 510 00:28:53,633 --> 00:28:57,902 but it would reflect the stuff our minds are attracted to. 511 00:28:57,904 --> 00:29:01,706 A computer algorithm would sort through your likes and dislikes 512 00:29:01,708 --> 00:29:06,544 and extrapolate a personality based on your experiences. 513 00:29:07,947 --> 00:29:10,315 Cathal's route to resurrection 514 00:29:10,317 --> 00:29:13,284 might bring something similar to you back to life. 515 00:29:13,286 --> 00:29:19,424 But is there a way to exactly re-create your inner self? 516 00:29:19,426 --> 00:29:22,460 This man says yes. 517 00:29:23,395 --> 00:29:27,298 We just need the right tools for the job. 518 00:29:31,258 --> 00:29:33,893 Your mind is the product 519 00:29:33,895 --> 00:29:38,965 of 100 trillion neural connections in your brain. 520 00:29:38,967 --> 00:29:42,935 This dense pattern is you. 521 00:29:42,937 --> 00:29:47,406 And when the brain dies, you die. 522 00:29:47,408 --> 00:29:50,643 What if we could separate the contents of our minds 523 00:29:50,645 --> 00:29:53,045 from our brains? 524 00:29:53,047 --> 00:29:56,282 If we could pull the essence of who you are 525 00:29:56,284 --> 00:29:59,318 out of the fragile biology of your brain 526 00:29:59,320 --> 00:30:01,988 and put it into another container, 527 00:30:01,990 --> 00:30:05,358 you could live again. 528 00:30:05,360 --> 00:30:07,193 [ Train whistle blows ] 529 00:30:09,096 --> 00:30:12,965 By day, Ken Hayworth is a neuroscientist 530 00:30:12,967 --> 00:30:16,602 at a prestigious Massachusetts University. 531 00:30:16,604 --> 00:30:20,639 In his off hours, he runs the Brain Preservation Foundation, 532 00:30:20,641 --> 00:30:25,011 which looks for ways to resurrect our minds after death. 533 00:30:25,013 --> 00:30:28,514 I want to see the future, and death is preventing that. 534 00:30:28,516 --> 00:30:33,386 But if we can preserve and map our brains, we can get there. 535 00:30:33,388 --> 00:30:35,187 [ Train whistle blows ] 536 00:30:40,327 --> 00:30:43,896 The wiring of your brain is like this train track, 537 00:30:43,898 --> 00:30:47,099 only the total length of wires in your brain 538 00:30:47,101 --> 00:30:49,802 is actually billions of times longer 539 00:30:49,804 --> 00:30:52,405 than the length of this toy track. 540 00:30:52,407 --> 00:30:55,341 And the number of switching points in your brain 541 00:30:55,343 --> 00:30:58,310 numbers in the hundreds of trillions. 542 00:31:00,547 --> 00:31:04,050 We call this set of wires and switches in a human brain 543 00:31:04,052 --> 00:31:05,718 the connectome. 544 00:31:05,720 --> 00:31:08,587 The connectome is the seat of all of our memory, 545 00:31:08,589 --> 00:31:14,727 and it is the generator of our thought and our consciousness. 546 00:31:14,729 --> 00:31:19,298 If we could copy this set of trillions of connections, 547 00:31:19,300 --> 00:31:26,172 we could re-create you, even after your body has died. 548 00:31:26,174 --> 00:31:28,974 Freeman: The way to rescue 549 00:31:28,976 --> 00:31:33,879 all the information held in the connectome, Ken says, 550 00:31:33,881 --> 00:31:37,583 is to treat the brain like a computer. 551 00:31:37,585 --> 00:31:39,852 So, this is a dead computer. 552 00:31:39,854 --> 00:31:41,620 It's way out of date. 553 00:31:41,622 --> 00:31:43,756 It has a burned-out motherboard, 554 00:31:43,758 --> 00:31:46,959 and there's really essentially nothing I can do 555 00:31:46,961 --> 00:31:48,961 to repair this computer. 556 00:31:48,963 --> 00:31:52,798 And I'm really sad about that, because this particular computer 557 00:31:52,800 --> 00:31:55,701 has all my wedding photographs, my PhD thesis, 558 00:31:55,703 --> 00:31:57,636 and I'm going to just toss it 559 00:31:57,638 --> 00:32:00,139 into the trash and lose it forever. 560 00:32:00,141 --> 00:32:02,241 But, of course, that's not true. 561 00:32:02,243 --> 00:32:04,043 Those pieces of information 562 00:32:04,045 --> 00:32:06,812 are stored digitally on this hard drive, 563 00:32:06,814 --> 00:32:11,484 and I can copy that information onto another hard drive. 564 00:32:11,486 --> 00:32:16,388 Now, what I'm saying is that neuroscience has told us 565 00:32:16,390 --> 00:32:19,058 that we, in essence, are digital information 566 00:32:19,060 --> 00:32:22,828 stored in the synaptic connections within our brain. 567 00:32:22,830 --> 00:32:25,798 If we preserve that brain at our death, 568 00:32:25,800 --> 00:32:29,568 then that information that makes us unique -- 569 00:32:29,570 --> 00:32:32,505 all of those memories -- they're not lost, 570 00:32:32,507 --> 00:32:35,107 and they can be potentially brought back 571 00:32:35,109 --> 00:32:38,611 just the same way digital information can be brought back 572 00:32:38,613 --> 00:32:40,779 by putting it in a new computer. 573 00:32:40,781 --> 00:32:45,718 Freeman: Software is physically written onto a hard drive. 574 00:32:45,720 --> 00:32:48,387 Make an exact copy of a drive, 575 00:32:48,389 --> 00:32:53,192 and you have an exact copy of the information it contains. 576 00:32:53,194 --> 00:32:56,862 Ken believes all the information in your brain 577 00:32:56,864 --> 00:32:58,831 can also be copied and stored. 578 00:32:58,833 --> 00:33:01,167 All you have to do to preserve 579 00:33:01,169 --> 00:33:03,502 the connectome's trillions of neural connections 580 00:33:03,504 --> 00:33:05,471 is to copy the brain's hardware... 581 00:33:07,641 --> 00:33:09,508 ...one slice at a time. 582 00:33:09,510 --> 00:33:13,946 Ken's brain-scanning assembly line would work like this. 583 00:33:13,948 --> 00:33:15,915 At the moment of death, 584 00:33:15,917 --> 00:33:20,252 the brain is extracted and preserved in plastic. 585 00:33:20,254 --> 00:33:24,523 The brain is then chopped by a heated diamond knife 586 00:33:24,525 --> 00:33:31,130 into 20-micron cubes 40,000 times thinner than a human hair. 587 00:33:31,132 --> 00:33:35,901 These tiny slices are sliced again, 1,000 times thinner, 588 00:33:35,903 --> 00:33:39,505 then scanned by ion beams. 589 00:33:39,507 --> 00:33:42,841 The process is repeated millions of times 590 00:33:42,843 --> 00:33:45,744 until the entire brain is digitized. 591 00:33:45,746 --> 00:33:47,479 Hmm? Hmm? 592 00:33:47,481 --> 00:33:50,549 It is technology that exists today. 593 00:33:50,551 --> 00:33:53,852 We mapped small bits of neural tissue 594 00:33:53,854 --> 00:33:56,822 at this ultimate resolution already. 595 00:33:56,824 --> 00:33:58,958 Freeman: The resolution is so high 596 00:33:58,960 --> 00:34:03,329 that we cannot only see the connections between neurons -- 597 00:34:03,331 --> 00:34:07,533 we can also determine their strength and type. 598 00:34:07,535 --> 00:34:11,503 Once we have the ability to map a human brain 599 00:34:11,505 --> 00:34:14,039 and once we have the knowledge 600 00:34:14,041 --> 00:34:17,209 of how that generates a human mind, 601 00:34:17,211 --> 00:34:23,983 we will be able to simulate that brain in a computer substrate 602 00:34:23,985 --> 00:34:28,721 and bring that individual back to life 603 00:34:28,723 --> 00:34:31,824 inside of a computer simulation. 604 00:34:31,826 --> 00:34:34,760 Freeman: Mapping the human mind today 605 00:34:34,762 --> 00:34:39,598 would require an enormously expensive Apollo-sized project. 606 00:34:39,600 --> 00:34:44,236 But as technology gets cheaper, that could change. 607 00:34:44,238 --> 00:34:48,374 So, whereas it's tens of billions of dollars today 608 00:34:48,376 --> 00:34:50,209 to map a whole human mind, 609 00:34:50,211 --> 00:34:54,713 it will be thousands of dollars 100 years from now. 610 00:34:54,715 --> 00:34:59,618 Anybody that wants to get to that future technology 611 00:34:59,620 --> 00:35:03,489 just 100 years from now can get their brain preserved. 612 00:35:03,491 --> 00:35:08,661 Freeman: Imagine the future in which every hospital is equipped 613 00:35:08,663 --> 00:35:11,797 to preserve your brain if you dip near death. 614 00:35:11,799 --> 00:35:16,068 Thousands of brains, sliced and scanned, 615 00:35:16,070 --> 00:35:20,506 will be ready to form a new population of the formerly dead. 616 00:35:20,508 --> 00:35:22,941 Hayworth: That person's brain 617 00:35:22,943 --> 00:35:25,411 that's sitting there on the shelf for the last 100 years 618 00:35:25,413 --> 00:35:29,214 can be taken off, sliced, imaged, 619 00:35:29,216 --> 00:35:32,618 and downloaded into a computer simulation. 620 00:35:32,620 --> 00:35:37,823 And that person wakes up like they were in a long sleep. 621 00:35:39,592 --> 00:35:46,131 Freeman: And if we live on as digital copies of ourselves, what then? 622 00:35:46,133 --> 00:35:49,601 What would life be like as a computer program? 623 00:35:49,603 --> 00:35:52,237 How would we relate to each other? 624 00:35:52,239 --> 00:35:56,342 Could we bear to live without physical sensation? 625 00:35:58,144 --> 00:35:59,645 To bring back a brain 626 00:35:59,647 --> 00:36:02,147 and just leave it in some computer 627 00:36:02,149 --> 00:36:05,184 without legs, without arms, without eyes -- 628 00:36:05,186 --> 00:36:09,655 of course, that would be an experience worse than death. 629 00:36:09,657 --> 00:36:13,459 Freeman: Resurrecting the mind may not be enough. 630 00:36:13,461 --> 00:36:17,029 To truly live again, we will want to see the world around us 631 00:36:17,031 --> 00:36:18,897 and touch the ones we love. 632 00:36:18,899 --> 00:36:22,601 The challenges of restoring a mind to a biological body 633 00:36:22,603 --> 00:36:24,737 seem insurmountable. 634 00:36:24,739 --> 00:36:28,006 But there is another option. 635 00:36:28,008 --> 00:36:30,476 Perhaps we could build new bodies 636 00:36:30,478 --> 00:36:33,379 to carry our resurrected minds -- 637 00:36:33,381 --> 00:36:37,683 robot bodies, like these. 638 00:36:41,932 --> 00:36:46,068 Someday, we may be able to preserve our minds, 639 00:36:46,070 --> 00:36:48,971 but our resurrection will be incomplete 640 00:36:48,973 --> 00:36:50,840 if we don't have bodies -- 641 00:36:50,842 --> 00:36:53,542 not these fragile bags of chemicals, 642 00:36:53,544 --> 00:36:56,979 but perfect replicas of ourselves that never age 643 00:36:56,981 --> 00:36:59,682 and can be constantly upgraded -- 644 00:36:59,684 --> 00:37:04,653 robot vessels to carry our digitized minds. 645 00:37:04,655 --> 00:37:06,655 Think of it. 646 00:37:17,834 --> 00:37:22,605 In Japan, robots are a part of daily life. 647 00:37:22,607 --> 00:37:24,306 Most of them work in factories 648 00:37:24,308 --> 00:37:28,043 and don't look too different from the machines they build. 649 00:37:28,045 --> 00:37:32,148 But Japan also leads the world in building androids 650 00:37:32,150 --> 00:37:36,452 that straddle the line between humans and machines. 651 00:37:38,588 --> 00:37:42,525 If Hiroshi Ishiguro has his way, the world of the future 652 00:37:42,527 --> 00:37:45,694 will be filled with replicants so realistic, 653 00:37:45,696 --> 00:37:49,932 you can't tell them apart from flesh-and-blood people. 654 00:38:06,716 --> 00:38:12,755 Hiroshi's lab tests how much or how little humanity 655 00:38:12,757 --> 00:38:17,726 androids need to be accepted by humans. 656 00:38:17,728 --> 00:38:20,896 They have produced a line of robots 657 00:38:20,898 --> 00:38:22,898 ranging from near human 658 00:38:22,900 --> 00:38:26,902 to these almost impressionistic creatures. 659 00:38:41,852 --> 00:38:44,587 The Elfoid robots have a bare minimum 660 00:38:44,589 --> 00:38:46,088 of human characteristics, 661 00:38:46,090 --> 00:38:49,492 yet people are able to relate to them. 662 00:38:49,494 --> 00:38:53,996 In the future, this might be the low-budget option 663 00:38:53,998 --> 00:38:55,898 for your robot body. 664 00:38:55,900 --> 00:38:59,368 It's simple, but it does the job. 665 00:38:59,370 --> 00:39:01,270 [ Speaking Japanese ] 666 00:39:01,272 --> 00:39:04,406 Freeman: For now, the Elfoid is remote-controlled, 667 00:39:04,408 --> 00:39:07,076 like all of Hiroshi's robots. 668 00:39:07,078 --> 00:39:10,980 Software reads the facial expressions of the operator 669 00:39:10,982 --> 00:39:13,883 and transmits them to tiny actuators 670 00:39:13,885 --> 00:39:16,986 under the android's synthetic skin. 671 00:39:16,988 --> 00:39:21,190 These mimic human facial muscles. 672 00:39:21,192 --> 00:39:23,192 [ Speaking Japanese ] 673 00:39:29,232 --> 00:39:33,469 At the other end of the ladder are the Geminoids, 674 00:39:33,471 --> 00:39:36,672 meant to mirror humans as closely as possible. 675 00:39:36,674 --> 00:39:40,976 The Geminoids are replicas of real people. 676 00:39:40,978 --> 00:39:44,313 Imagine a body like this 677 00:39:44,315 --> 00:39:48,584 loaded with the contents of your digitized mind, 678 00:39:48,586 --> 00:39:50,953 or perhaps your disembodied consciousness 679 00:39:50,955 --> 00:39:53,556 would operate the android from a mainframe, 680 00:39:53,558 --> 00:39:58,093 just as these robots are controlled from a distance. 681 00:39:58,095 --> 00:40:01,797 Hiroshi is already working on the technology 682 00:40:01,799 --> 00:40:07,069 to connect our minds to the androids. 683 00:40:07,071 --> 00:40:08,504 Ishiguro: If possible... 684 00:40:18,748 --> 00:40:23,052 Freeman: If Hiroshi does perfect a brain/machine interface, 685 00:40:23,054 --> 00:40:26,589 he will probably first test it on himself -- 686 00:40:26,591 --> 00:40:31,393 or, more precisely, his replicant. 687 00:40:31,395 --> 00:40:33,729 Yeah, yeah. He's restarting -- restarting. 688 00:40:33,731 --> 00:40:34,930 Okay. 689 00:40:34,932 --> 00:40:36,832 Yeah, we have come -- we have come back now. 690 00:40:36,834 --> 00:40:38,634 [ Laughs ] 691 00:40:38,636 --> 00:40:39,668 Okay. 692 00:40:39,670 --> 00:40:41,637 Now it's okay. Can you look at me? 693 00:40:41,639 --> 00:40:43,539 Mm-hmm. All right. 694 00:40:43,541 --> 00:40:46,575 Hiroshi often sends his doppelganger to other countries 695 00:40:46,577 --> 00:40:48,010 to represent him 696 00:40:48,012 --> 00:40:52,748 or to teach classes that he's too busy to attend in the flesh. 697 00:40:52,750 --> 00:40:55,150 How do people respond to this and me? 698 00:40:55,152 --> 00:40:57,019 Well -- well, maybe they were -- 699 00:40:57,021 --> 00:40:59,922 in the first contact, they were a little bit nervous, 700 00:40:59,924 --> 00:41:01,156 but, you know, once -- 701 00:41:01,158 --> 00:41:03,492 as you know that, once you start to talk, 702 00:41:03,494 --> 00:41:06,962 they can concentrate on the -- in a conversation. 703 00:41:08,932 --> 00:41:14,336 Hiroshi has essentially created a robot version of himself, 704 00:41:14,338 --> 00:41:17,072 and the better his hardware gets, 705 00:41:17,074 --> 00:41:20,476 the more his androids pass for real people. 706 00:41:27,450 --> 00:41:30,686 The Geminoid "F" is an android so lifelike, 707 00:41:30,688 --> 00:41:33,355 it has performed onstage in plays, 708 00:41:33,357 --> 00:41:37,526 but its inventor is never satisfied. 709 00:41:47,504 --> 00:41:50,839 Thank you for answering my questions, Professor. 710 00:41:50,841 --> 00:41:52,374 You're welcome. 711 00:41:52,376 --> 00:41:55,744 Freeman: This could be the future face of the living dead -- 712 00:41:55,746 --> 00:41:59,682 not decaying corpses, but smooth silicon flesh -- 713 00:41:59,684 --> 00:42:05,854 robots carrying the minds of our long-lost loved ones. 714 00:42:15,131 --> 00:42:17,866 [ Breathes deeply ] 715 00:42:17,868 --> 00:42:24,840 The day when we never have to say goodbye may soon be at hand. 716 00:42:24,842 --> 00:42:28,944 But what would it be like to see your dead grandmother again, 717 00:42:28,946 --> 00:42:32,347 living inside a synthetic body? 718 00:42:32,349 --> 00:42:36,585 Would she still be the woman you knew? 719 00:42:36,587 --> 00:42:39,354 We won't know until it happens. 720 00:42:39,356 --> 00:42:41,857 The human race may one day be filled 721 00:42:41,859 --> 00:42:45,094 with new and unfamiliar ethnic groups. 722 00:42:45,096 --> 00:42:49,064 The people next door might be the robotic undead, 723 00:42:49,066 --> 00:42:51,834 and the great divide in society 724 00:42:51,836 --> 00:42:56,105 would be between those who have lived only once 725 00:42:56,107 --> 00:43:00,437 and those who are on their second or fifth body. 726 00:43:00,438 --> 00:43:04,438 == sync, corrected by elderman ==59310

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